Guide to the Human Genome
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Name: SMPD1 Sequence: fasta or formatted (631aa) NCBI GI: 56117840
Description:

sphingomyelin phosphodiesterase 1, acid lysosomal isoform 1 precursor

Referenced in:

Sphingomyelin, Ceramides, and Glycolipids
Lysosomes and Related Organelles

Other entries for this name:
alt prot [587aa] sphingomyelin phosphodiesterase 1, acid lysosomal isoform 2 precu...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.7         55           2
 C cysteine            2.9         18           2
 D aspartate           4.3         27           2
 E glutamate           4.1         26           2
 F phenylalanine       3.3         21           2
 G glycine             7.8         49           2
 H histidine           3.6         23           1
 I isoleucine          3.6         23           2
 K lysine              2.1         13           2
 L leucine            12.8         81           3
 M methionine          1.4          9           1
 N asparagine          3.2         20           1
 P proline            10.0         63           3
 Q glutamine           3.0         19           1
 R arginine            6.0         38           2
 S serine              6.7         42           2
 T threonine           4.6         29           2
 V valine              5.1         32           2
 W tryptophan          3.3         21           1
 Y tyrosine            3.5         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sphingomyelin phosphodiesterase 1, acid lysosomal is... 
SMPD1                 0.895   sphingomyelin phosphodiesterase 1, acid lysosomal is...
SMPDL3B               0.128   acid sphingomyelinase-like phosphodiesterase 3B isof...
SMPDL3A               0.115   acid sphingomyelinase-like phosphodiesterase 3A [Hom...
SMPDL3B               0.093   acid sphingomyelinase-like phosphodiesterase 3B isof...
WHAMM                 0.012   WAS protein homolog associated with actin, golgi me...
ROBO4                 0.009   roundabout homolog 4, magic roundabout 
JMY                   0.008   junction-mediating and regulatory protein 
SETD1B                0.008   SET domain containing 1B 
CAMTA2                0.008   calmodulin binding transcription activator 2 
ZFHX3                 0.008   AT-binding transcription factor 1 
WASF3                 0.008   WAS protein family, member 3 
VASP                  0.007   vasodilator-stimulated phosphoprotein 
HS3ST4                0.007   heparan sulfate D-glucosaminyl 3-O-sulfotransferase...
LMTK3                 0.007   lemur tyrosine kinase 3 
KDM6B                 0.006   lysine (K)-specific demethylase 6B 
SCAF1                 0.006   SR-related CTD-associated factor 1 
ZFHX4                 0.006   zinc finger homeodomain 4 
RAPH1                 0.006   Ras association and pleckstrin homology domains 1 is...
MLL4                  0.006   myeloid/lymphoid or mixed-lineage leukemia 4 
YLPM1                 0.006   YLP motif containing 1 
KLF16                 0.006   BTE-binding protein 4 
LOC100128074          0.006   PREDICTED: hypothetical protein 
PCLO                  0.006   piccolo isoform 2 
PCLO                  0.006   piccolo isoform 1 
EPS15L1               0.006   epidermal growth factor receptor pathway substrate 1...
KRBA1                 0.006   KRAB A domain containing 1 
FNBP4                 0.005   formin binding protein 4 
BCL6B                 0.005   B-cell CLL/lymphoma 6, member B (zinc finger protein...
MYO16                 0.005   myosin heavy chain Myr 8 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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