Guide to the Human Genome
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Search of human proteins with 241982780

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|241982780 programmed cell death 6 interacting protein
isoform 2 [Homo sapiens]
         (873 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|241982780 programmed cell death 6 interacting protein isoform...  1741   0.0  
gi|22027538 programmed cell death 6 interacting protein isoform ...  1723   0.0  
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...   257   4e-68
gi|239752482 PREDICTED: similar to programmed cell death 6 inter...   237   4e-62
gi|119120915 rhophilin 1 [Homo sapiens]                                96   1e-19
gi|228008333 rhophilin, Rho GTPase binding protein 2 [Homo sapiens]    89   2e-17
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     74   5e-13
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     74   5e-13
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    70   1e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 68   4e-11
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               67   6e-11
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    67   7e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          67   7e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          67   7e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          67   7e-11
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                67   9e-11
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     66   1e-10
gi|160707881 formin 2 [Homo sapiens]                                   66   2e-10
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    65   2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is...    65   3e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    65   4e-10
gi|210032580 SET domain containing 1B [Homo sapiens]                   64   6e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    64   6e-10
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   63   1e-09
gi|150170670 piccolo isoform 2 [Homo sapiens]                          63   1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          63   1e-09
gi|157168329 formin 1 [Homo sapiens]                                   62   2e-09
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    62   2e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens]                62   2e-09
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    62   2e-09

>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 1741 bits (4509), Expect = 0.0
 Identities = 873/873 (100%), Positives = 873/873 (100%)

Query: 1   MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK 60
           MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
Sbjct: 1   MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK 60

Query: 61  HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK 120
           HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
Sbjct: 61  HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK 120

Query: 121 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS 180
           SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
Sbjct: 121 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS 180

Query: 181 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKY 240
           PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKY
Sbjct: 181 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKY 240

Query: 241 FYFQEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV 300
           FYFQEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV
Sbjct: 241 FYFQEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV 300

Query: 301 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF 360
           NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF
Sbjct: 301 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF 360

Query: 361 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ 420
           EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ
Sbjct: 361 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ 420

Query: 421 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER 480
           SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER
Sbjct: 421 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER 480

Query: 481 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP 540
           WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP
Sbjct: 481 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP 540

Query: 541 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN 600
           SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN
Sbjct: 541 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN 600

Query: 601 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN 660
           EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN
Sbjct: 601 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN 660

Query: 661 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 720
           LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR
Sbjct: 661 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 720

Query: 721 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS 780
           EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS
Sbjct: 721 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS 780

Query: 781 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 840
           PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP
Sbjct: 781 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 840

Query: 841 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873
           VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
Sbjct: 841 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 1723 bits (4462), Expect = 0.0
 Identities = 868/873 (99%), Positives = 868/873 (99%), Gaps = 5/873 (0%)

Query: 1   MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK 60
           MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
Sbjct: 1   MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK 60

Query: 61  HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK 120
           HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
Sbjct: 61  HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK 120

Query: 121 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS 180
           SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
Sbjct: 121 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS 180

Query: 181 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKY 240
           PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK 
Sbjct: 181 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK- 239

Query: 241 FYFQEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV 300
               EVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV
Sbjct: 240 ----EVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV 295

Query: 301 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF 360
           NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF
Sbjct: 296 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF 355

Query: 361 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ 420
           EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ
Sbjct: 356 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ 415

Query: 421 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER 480
           SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER
Sbjct: 416 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER 475

Query: 481 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP 540
           WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP
Sbjct: 476 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP 535

Query: 541 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN 600
           SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN
Sbjct: 536 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN 595

Query: 601 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN 660
           EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN
Sbjct: 596 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN 655

Query: 661 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 720
           LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR
Sbjct: 656 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR 715

Query: 721 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS 780
           EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS
Sbjct: 716 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS 775

Query: 781 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 840
           PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP
Sbjct: 776 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 835

Query: 841 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873
           VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
Sbjct: 836 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 868


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23
           [Homo sapiens]
          Length = 1636

 Score =  257 bits (656), Expect = 4e-68
 Identities = 238/895 (26%), Positives = 408/895 (45%), Gaps = 66/895 (7%)

Query: 5   ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGA 64
           I + LK+  +      + KF+ + Y   GE    Y    ++L  LR+ AV  P D  EG 
Sbjct: 10  IWLDLKEAGDFHFQPAVKKFVLKNY---GENPEAYNEELKKLELLRQNAVRVPRD-FEGC 65

Query: 65  LETLLRYYDQICSIEPKFPFSENQ-ICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCV 123
              L +Y  Q+  ++ + P    Q   +  TW + F   S+    +K       YE++C+
Sbjct: 66  -SVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIK-------YEQACI 117

Query: 124 LFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDT 183
           L+N  AL S + A     ++EG+K++  H+Q A+GAF +++E    A S    VD+S   
Sbjct: 118 LYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYS----VDMSRQI 173

Query: 184 VGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKYFYF 243
           +     +ML QAQE    K+  D  K  ++A+++ Q  DY+ +A +  +  DT       
Sbjct: 174 LTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRI 233

Query: 244 QEVFPVLA-AKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAA----ELIKTVASRYDE 298
           Q+ +  L   K     A A  H    A++Q+KFGE +A  Q A     E IK    + D 
Sbjct: 234 QKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDT 293

Query: 299 YVNVKDFS-DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFT 357
             +   F+ D I     +AKKDNDFIYH+ VP L  L P+  A LVK  PVN P     T
Sbjct: 294 VQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVN-PTDPAVT 352

Query: 358 --DLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNL-PAAIEDVS 414
             D+F K+VP++  ++ + Y++ KA L+   +A++ +   + +  + S+ L P  ++++ 
Sbjct: 353 GPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLD 412

Query: 415 G-DTVPQSILTKSRSV-IEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDND 472
               +P  ++ K  ++ +    ++ + Q ++ L  +       L +   LL+E+E     
Sbjct: 413 AYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDEL---- 468

Query: 473 LRAKFKERWQR------TPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIV 526
           L  KF+E   +      T   EL + +R E   +  V +KA   + ++      H   + 
Sbjct: 469 LEQKFQEAVGQAGAISITSKAELAE-VRREWAKYMEVHEKASFTNSELHRAMNLHVGNLR 527

Query: 527 LLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSV--NFD 584
           LL  P  ++ AA+P+  PA + +   V+  LK +L+ + E++ +R  LE  L+ +    D
Sbjct: 528 LLSGPLDQVRAALPT--PALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDD 585

Query: 585 MTSKFLTA-LAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSK 643
           +T+  +T   ++   + EE L      + Y  L   ++++L  Q+ +L  +  ++ +++ 
Sbjct: 586 ITASLVTTDHSEMKKLFEEQL------KKYDQLKVYLEQNLAAQDRVLCALTEANVQYAA 639

Query: 644 MKQSNNEANLR-EEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFA 702
           +++  ++ + +    L+ L  +Y+ + +L+   +EG  FY +L   +     +      A
Sbjct: 640 VRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQA 699

Query: 703 RKTERDELL-KDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 761
           R+  R +LL ++L++     P+AP    P  + S A   A  PP    R++PP     P 
Sbjct: 700 REAARQQLLDRELKKKPPPRPTAPKPLLPRREESEA-VEAGDPPEEL-RSLPPDMVAGPR 757

Query: 762 RPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMP 821
              P     +  P    PSP  + T  P P    G  PP    GP     P  PG   MP
Sbjct: 758 L--PDTFLGSATPLHFPPSPFPSST-GPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMP 814

Query: 822 MPMGYNPYAYGQYNMPYPPVYHQSPG----QAPY----PGPQQPSYPFPQPPQQS 868
           +  G   Y    Y      V   SP      +PY    P P     P   PPQ S
Sbjct: 815 VAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFS 869



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 46/170 (27%), Positives = 61/170 (35%), Gaps = 23/170 (13%)

Query: 725  PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA 784
            P+  T     +P   H    P P P   PP  P PP +P P             P+    
Sbjct: 879  PATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHF 938

Query: 785  GTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGY---------------NPY 829
             +  PA    P   P PQ    P+P+    P   Q P+P+ +               +PY
Sbjct: 939  SSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998

Query: 830  AY----GQYNMPYPPVYHQ-SPGQAPYPGPQQPS---YPFPQPPQQSYYP 871
             Y    G    P PP++ Q  PG A  P P       +P P PPQ  + P
Sbjct: 999  PYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPP 1048



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 52/163 (31%), Positives = 65/163 (39%), Gaps = 21/163 (12%)

Query: 718  IAREPSAPSIPTPAYQSSPAGGHAPTP-------PTPAPRTMPPTKPQPPA-------RP 763
            I  +P     P P+    P     P P       P  AP  +PP  P P A       +P
Sbjct: 951  IGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQP 1010

Query: 764  PPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAP-PPQAQGPPYPTYPGYPGYCQMPM 822
            PPP+        A  P P  +G A P PS  P   P PP A GP   T P  P    + +
Sbjct: 1011 PPPLHTQLYPGPAQDPLPAHSG-ALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI 1069

Query: 823  PMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
                 P + GQ + P P +   SP  +P PGP  P  P  +PP
Sbjct: 1070 ---RGPSSAGQ-STPSPHLV-PSPAPSPGPGPVPPRPPAAEPP 1107



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 47/157 (29%), Positives = 62/157 (39%), Gaps = 16/157 (10%)

Query: 726 SIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP-----ARPPPPVLPANRAPSATAPS 780
           S P     SSP  G  P PP     + PP +   P      RP    + + +AP  +  +
Sbjct: 837 SSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTA 896

Query: 781 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 840
           P    T AP P   P   PPPQ    P PT   YP   + P+P  ++  +      P P 
Sbjct: 897 PRPNPTPAPPPPCFP--VPPPQ----PLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPR 950

Query: 841 VYHQ-SPGQAPYP----GPQQPSYPFPQPPQQSYYPQ 872
           +  Q  P   P+P    GPQ P  P P      + PQ
Sbjct: 951 IGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQ 987



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 34/93 (36%), Positives = 40/93 (43%), Gaps = 17/93 (18%)

Query: 728  PTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR--PPPPVLPAN-RAPSATAPSPVGA 784
            P PA    PA  H+   P P+P   PP  P PP    P P   P   +A   T   P  A
Sbjct: 1020 PGPAQDPLPA--HSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSA 1075

Query: 785  GTA--------APAPSQTPGSAP--PPQAQGPP 807
            G +        +PAPS  PG  P  PP A+ PP
Sbjct: 1076 GQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPP 1108



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 10/80 (12%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSP 781
            P  P  P P     PA    P  P  AP T+        + P P ++P      + APSP
Sbjct: 1039 PGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP------SPAPSP 1092

Query: 782  VGAGTAAPAPSQTPGSAPPP 801
             G G   P P + P + PPP
Sbjct: 1093 -GPG---PVPPRPPAAEPPP 1108



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 14/112 (12%)

Query: 696  CSDIVFARKTERDELLKDLQQ----------SIAREPSAPSIPTPAYQSSPAG---GHAP 742
            C  +  A  ++++ L +D Q           SI    +  SI  P    SP     G A 
Sbjct: 1466 CKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAE 1525

Query: 743  TPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQT 794
             P  P P ++P + P P + PPP   P   AP      PV    ++  PS +
Sbjct: 1526 PPGLP-PASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 4/79 (5%)

Query: 738  GGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGS 797
            GG  P     A       +P      P   LP    P    P+ +   T  P+ S  P S
Sbjct: 1490 GGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLS 1549

Query: 798  APPPQA----QGPPYPTYP 812
            +P P+A    + PP P  P
Sbjct: 1550 SPLPEAPQPKEEPPVPEAP 1568


>gi|239752482 PREDICTED: similar to programmed cell death 6
           interacting protein [Homo sapiens]
          Length = 128

 Score =  237 bits (604), Expect = 4e-62
 Identities = 124/128 (96%), Positives = 124/128 (96%)

Query: 585 MTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKM 644
           MTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKM
Sbjct: 1   MTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKM 60

Query: 645 KQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARK 704
           KQSNNEANLREEVLKNLATA DNFVELVAN KEGTKFYNELTEILVRFQNKCSDIV A K
Sbjct: 61  KQSNNEANLREEVLKNLATACDNFVELVANSKEGTKFYNELTEILVRFQNKCSDIVLAWK 120

Query: 705 TERDELLK 712
           TERDELLK
Sbjct: 121 TERDELLK 128


>gi|119120915 rhophilin 1 [Homo sapiens]
          Length = 670

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 70/196 (35%), Positives = 102/196 (52%), Gaps = 16/196 (8%)

Query: 5   ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGA 64
           I + LK+T E+D + PL + I   +   GE+ A Y     EL  LR+A   R   ++E  
Sbjct: 110 IPLGLKETKELDWSTPLKELISVHF---GEDGASYEAEIRELEALRQAM--RTPSRNESG 164

Query: 65  LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVL 124
           LE L  YY+Q+C ++ +F      + L F W D     SL G  V     +L +EK  VL
Sbjct: 165 LELLTAYYNQLCFLDARFLTPARSLGLFFHWYD-----SLTG--VPAQQRALAFEKGSVL 217

Query: 125 FNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTV 184
           FN  AL +QI A Q+    EG + A + +Q A+GAF  ++E      S  P+ D+S  ++
Sbjct: 218 FNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLREN----FSHAPSPDMSAASL 273

Query: 185 GTLSLIMLAQAQEVFF 200
             L  +M+AQAQE  F
Sbjct: 274 CALEQLMMAQAQECVF 289


>gi|228008333 rhophilin, Rho GTPase binding protein 2 [Homo sapiens]
          Length = 686

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 74/228 (32%), Positives = 117/228 (51%), Gaps = 19/228 (8%)

Query: 5   ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGA 64
           I + LK+T +VD A  L  FI + Y    E+   Y     +L  LR+A   R   + E  
Sbjct: 113 IPLGLKETKDVDFAVVLKDFILEHY---SEDGYLYEDEIADLMDLRQAC--RTPSRDEAG 167

Query: 65  LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVL 124
           +E L+ Y+ Q+  +E +F     Q+ L FTW D     SL G  V ++  +L  EK+ VL
Sbjct: 168 VELLMTYFIQLGFVESRFFPPTRQMGLLFTWYD-----SLTG--VPVSQQNLLLEKASVL 220

Query: 125 FNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTV 184
           FN  AL +QI    +     GL+ A   +Q A+G   ++K+T     +  P+ D+SP  +
Sbjct: 221 FNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDT----FTHTPSYDMSPAML 276

Query: 185 GTLSLIMLAQAQEVFFLKATRDKMKDA--IIAKLANQAADYFGDAFKQ 230
             L  +MLAQAQE  F K +   +++   ++ K+A +AA   G+ ++Q
Sbjct: 277 SVLVKMMLAQAQESVFEKISLPGIRNEFFMLVKVAQEAAK-VGEVYQQ 323


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 84/316 (26%), Positives = 117/316 (37%), Gaps = 72/316 (22%)

Query: 618 TKVQESLKKQEGLLKNIQ----VSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVA 673
           TKV++S  K   L K +       H+   +MK+  ++   + + L+    A  +  + +A
Sbjct: 463 TKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIA 522

Query: 674 NLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPS-IPTPAY 732
             K+  +   E++++         ++  A+K    E+      +I   PS PS  P P  
Sbjct: 523 TEKQDLEA--EVSQLTGEVAKLTKELEDAKK----EMASLSAAAITVPPSVPSRAPVPPA 576

Query: 733 QSSP--AGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPAN-------RAPSATA----- 778
              P  +G   P PP P   T PP  P PP  PPPP LP           P  TA     
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSLPGGTAISPPP 634

Query: 779 ----------PSPVGAGTAAPAPSQTPGSA---PPPQAQG-----PPYPTYPG------- 813
                     P P+  G   P+PS  PG     PPP   G     PP P  PG       
Sbjct: 635 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694

Query: 814 ---YPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPG--------------PQQ 856
               PG   MP P    P   G   +P PP +   PG  P P               P  
Sbjct: 695 PPPLPGEAGMPPP---PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 751

Query: 857 PSYPFPQPPQQSYYPQ 872
           P  PF   P++ Y P+
Sbjct: 752 PVLPFGLTPKKLYKPE 767


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 84/316 (26%), Positives = 117/316 (37%), Gaps = 72/316 (22%)

Query: 618 TKVQESLKKQEGLLKNIQ----VSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVA 673
           TKV++S  K   L K +       H+   +MK+  ++   + + L+    A  +  + +A
Sbjct: 472 TKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIA 531

Query: 674 NLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPS-IPTPAY 732
             K+  +   E++++         ++  A+K    E+      +I   PS PS  P P  
Sbjct: 532 TEKQDLEA--EVSQLTGEVAKLTKELEDAKK----EMASLSAAAITVPPSVPSRAPVPPA 585

Query: 733 QSSP--AGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPAN-------RAPSATA----- 778
              P  +G   P PP P   T PP  P PP  PPPP LP           P  TA     
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSLPGGTAISPPP 643

Query: 779 ----------PSPVGAGTAAPAPSQTPGSA---PPPQAQG-----PPYPTYPG------- 813
                     P P+  G   P+PS  PG     PPP   G     PP P  PG       
Sbjct: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703

Query: 814 ---YPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPG--------------PQQ 856
               PG   MP P    P   G   +P PP +   PG  P P               P  
Sbjct: 704 PPPLPGEAGMPPP---PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 760

Query: 857 PSYPFPQPPQQSYYPQ 872
           P  PF   P++ Y P+
Sbjct: 761 PVLPFGLTPKKLYKPE 776


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 53/167 (31%), Positives = 65/167 (38%), Gaps = 24/167 (14%)

Query: 722 PSAPSIPTPAYQS------SPAGGHAPTPPTPAPRTMPPTKPQPPAR---PPPPVLPANR 772
           P  P  P PA Q+       P G   P  P P  + +PP    PP R   PPPPVL   +
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282

Query: 773 APSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPT---YPGYPGYCQMPMPMGYNPY 829
                   P+  G   P P   P   PPP  QGPP P     P  PG    P+ +   P+
Sbjct: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342

Query: 830 AYGQYNMPYPPVYHQSPGQAPYP-----------GPQQPSYPFPQPP 865
             G      PP  H +P   P P           GP  P+ P+ +PP
Sbjct: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGRPP 388



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 41/131 (31%), Positives = 43/131 (32%), Gaps = 17/131 (12%)

Query: 720 REPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPV------------ 767
           R P     P   +   P G   P PP P P   PP  P PP + PPP             
Sbjct: 272 RPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPL 331

Query: 768 -LPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGY 826
             P   AP    P P   G   PAP   P   PPP   G P     G P       P   
Sbjct: 332 GPPLTLAPPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--- 387

Query: 827 NPYAYGQYNMP 837
            PY  G Y  P
Sbjct: 388 PPYDRGDYGPP 398



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 48/137 (35%), Positives = 55/137 (40%), Gaps = 39/137 (28%)

Query: 736 PAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTP 795
           PAG   P PP PA +T     P+PP  PP P  P         P P   G   P P    
Sbjct: 220 PAGPGGPPPPFPAGQT----PPRPPLGPPGPPGP---------PGPPPPGQVLPPPL--- 263

Query: 796 GSAPPPQAQGPPYPT-YPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP 854
            + PP +   PP P  +PG P + Q P+     P   G    P PPV    PG  P PGP
Sbjct: 264 -AGPPNRGDRPPPPVLFPGQP-FGQPPL----GPLPPG----PPPPV----PGYGPPPGP 309

Query: 855 QQPSYPFPQPPQQSYYP 871
                    PPQQ   P
Sbjct: 310 P--------PPQQGPPP 318



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 43/140 (30%), Positives = 50/140 (35%), Gaps = 12/140 (8%)

Query: 733 QSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVG--AGTAAPA 790
           Q     G  P       R   P  P      PPP  PA + P      P G       P 
Sbjct: 199 QGGRGRGRFPGAVPGGDRFPGPAGPG----GPPPPFPAGQTPPRPPLGPPGPPGPPGPPP 254

Query: 791 PSQT---PGSAPPPQAQGPPYPT-YPGYP-GYCQM-PMPMGYNPYAYGQYNMPYPPVYHQ 844
           P Q    P + PP +   PP P  +PG P G   + P+P G  P   G    P PP   Q
Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQ 314

Query: 845 SPGQAPYPGPQQPSYPFPQP 864
            P   P P P +P  P   P
Sbjct: 315 GPPPPPGPFPPRPPGPLGPP 334



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 42/132 (31%), Positives = 49/132 (37%), Gaps = 18/132 (13%)

Query: 744 PPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQA 803
           PP  + R   P   +   R P  V   +R P         AG   P P    G  PP   
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP-------AGPGGPPPPFPAGQTPPRPP 240

Query: 804 QGPPYPTYPGYPGYCQ----MPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSY 859
            GPP P  PG PG       +P P+   P    + + P PPV    PGQ     P  P  
Sbjct: 241 LGPPGP--PGPPGPPPPGQVLPPPLAGPP---NRGDRPPPPVLF--PGQPFGQPPLGPLP 293

Query: 860 PFPQPPQQSYYP 871
           P P PP   Y P
Sbjct: 294 PGPPPPVPGYGP 305


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 55/174 (31%), Positives = 67/174 (38%), Gaps = 21/174 (12%)

Query: 702 ARKTERDELLKDLQQSIAREPSAP--SIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQ- 758
           ++K  ++E   D   + + +  AP  S+P    Q+ P  G  P  P PAP   PP  P  
Sbjct: 370 SQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTG 429

Query: 759 -----PPARPP---PPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPT 810
                PP  PP   PP +P  R P      P       P P + PG  P P    PP P 
Sbjct: 430 LPPGPPPGAPPFLRPPGMPGLRGPLPRLLPP------GPPPGRPPGPPPGPPPGLPPGPP 483

Query: 811 YPGYPGYCQMPMPMGYNPYAYGQYNMP-YPPVYHQSPG---QAPYPGPQQPSYP 860
             G P     P P G  P   G    P  PP+    PG    AP P P   S P
Sbjct: 484 PRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAP 537



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 35/102 (34%), Positives = 37/102 (36%), Gaps = 15/102 (14%)

Query: 720 REPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
           R P  P +  P  +  P G     PP P P   P   P PP R PPP LP    P    P
Sbjct: 443 RPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPP 502

Query: 780 -------------SPVGAGTAAPAPSQTPG--SAPPPQAQGP 806
                         P   G   PAP   PG  SAPP   Q P
Sbjct: 503 RPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 29/223 (13%)

Query: 646 QSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKT 705
           + N E +  EE    L+     F ++    ++  K   ELT +           +     
Sbjct: 291 RDNGERDNNEEKKSGLSV---RFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGR 347

Query: 706 ERDELLKDLQQSIAREPSAPSIPTPAYQS---SPAGGHAPTPPTPAPRTMPPTKPQPPAR 762
           E +E  +D  +  + +  A       ++    S     A +     P+++PP++ Q P  
Sbjct: 348 EVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPM 407

Query: 763 PPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPM 822
           P PP L    AP    P P         P+  P   PPP A  PP+   PG PG  + P+
Sbjct: 408 PGPPPLGPPPAPPLRPPGP---------PTGLP-PGPPPGA--PPFLRPPGMPG-LRGPL 454

Query: 823 PMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
           P            +P  P   + PG  P P P  P  P P+ P
Sbjct: 455 PR----------LLPPGPPPGRPPGPPPGPPPGLPPGPPPRGP 487



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 39/187 (20%), Positives = 77/187 (41%), Gaps = 25/187 (13%)

Query: 624 LKKQEGLLKNIQ-VSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFY 682
           +K  + ++++++ +   EF+ ++Q      + ++  K L   ++  + L    KE    Y
Sbjct: 47  MKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYE--KENPDIY 104

Query: 683 NELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAP 742
            EL ++ V ++ K + +     ++  + +K+     A+     SIP P    +P+  +  
Sbjct: 105 KELRKLEVEYEQKRAQL-----SQYFDAVKN-----AQHVEVESIPLPDMPHAPS--NIL 152

Query: 743 TPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQ 802
               P P   PP+  +  +   PP    +  P       +G G     P   PG  PP  
Sbjct: 153 IQDIPLPGAQPPSILKKTSAYGPPTRAVSILPL------LGHGV----PRLPPGRKPPGP 202

Query: 803 AQGPPYP 809
             GPP P
Sbjct: 203 PPGPPPP 209


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 59/174 (33%), Positives = 68/174 (39%), Gaps = 35/174 (20%)

Query: 720 REPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
           R P   S+P P     P GG  P PP      MPPT P P   P PP LP   AP    P
Sbjct: 244 RPPLPESLPPP-----PPGG-LPLPP------MPPTGPAPSGPPGPPQLPP-PAPGVHPP 290

Query: 780 SPV----GAGTAAPAPS----------QTPGSAPPPQAQGPPYP-TYPGYPGY------C 818
           +PV     +G   PAP             PG  PP     PP P  +P  PG        
Sbjct: 291 APVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGV 350

Query: 819 QMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQ 872
             P P G +P A G +  P   V+ Q+PG  P      P  P   PP    +PQ
Sbjct: 351 HPPAP-GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQ 403



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 57/156 (36%), Positives = 65/156 (41%), Gaps = 18/156 (11%)

Query: 722 PSAPSIPTPAYQSSPA--GGHAPTPPT--PAPRTMPPTK----PQPPARPPPP-VLPANR 772
           P AP +  PA    P   G H P P    PAP   PPT     P P   PP P V P   
Sbjct: 289 PPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPP-- 346

Query: 773 APSATAPSPVGAGTAAPAPSQTPGSAPPPQAQG--PPYP-TYPGYPGYCQMPMPMGYNPY 829
           AP    P+P G    AP     P +   PQA G  P  P  +P  PG    P   G +P 
Sbjct: 347 APGVHPPAP-GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGV--HPPAPGMHPQ 403

Query: 830 AYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
           A G +  P P V+  +PG  P P    PS P   PP
Sbjct: 404 APGVHPQP-PGVHPSAPGVHPQPPGVHPSNPGVHPP 438



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 13/140 (9%)

Query: 740 HAPTPPTPAPRTMPPTKPQPPARPPPPVL----PANRAPSATAPSPVGAGTAAPAPSQTP 795
           H      PAP ++ P  P    RPPPP++    P    P +  P P G     P P   P
Sbjct: 211 HFKMEKPPAPPSL-PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGP 269

Query: 796 GSAPPPQAQGPPY--PTYPGY--PGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPY 851
             + PP   GPP   P  PG   P     P   G +P A G  + P P V+  +PG  P 
Sbjct: 270 APSGPP---GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPG-VHPPAPGVHPPAPGVHPP 325

Query: 852 PGPQQPSYPFPQPPQQSYYP 871
                P  P   PP    +P
Sbjct: 326 TSGVHPPAPGVHPPAPGVHP 345



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 57/172 (33%), Positives = 65/172 (37%), Gaps = 33/172 (19%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTP-----APRTMPPTK----PQPPARPPPPVLPANR 772
           P  P  PT    S P G     PP P     AP   PP      P P   PP P +    
Sbjct: 260 PLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVH--- 316

Query: 773 APSATAPSPVGAGTAAPAPS---QTPGSAPPPQAQGPPYP-TYPGYPGYCQMPMPMGYNP 828
            P A    P  +G   PAP      PG  PP     PP P  +P  PG    P   G +P
Sbjct: 317 -PPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV-HPPPSAGVHP 374

Query: 829 YAYGQY------NMPYPPVYHQSPG---QAPYPGPQ----QPSYP--FPQPP 865
            A G +      +   P V+  +PG   QAP   PQ     PS P   PQPP
Sbjct: 375 QAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPP 426



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 50/155 (32%), Positives = 57/155 (36%), Gaps = 31/155 (20%)

Query: 722 PSAPSI--PTPAYQSSPAGGHAPTPPT--PAPRTMPPTK----PQPPARPPP-----PVL 768
           P AP +  PT        G H P P    PAP   PP      P P   PPP     P  
Sbjct: 317 PPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQA 376

Query: 769 PANRAPSATAPSPVGAGTAAPAPS---QTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMG 825
           P    P+A A  P   G   PAP    Q PG  P P         +P  PG    P P G
Sbjct: 377 PGVH-PAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPG------VHPSAPGV--HPQPPG 427

Query: 826 YNPYAYGQY------NMPYPPVYHQSPGQAPYPGP 854
            +P   G +       M  PP+  + PG  P P P
Sbjct: 428 VHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 50/164 (30%), Positives = 59/164 (35%), Gaps = 27/164 (16%)

Query: 733 QSSPAGGHAPTPPTPAPRTMPPTKPQPPARPP---------------PPVLPANRAPSAT 777
           +  PA    P  P    R  PP     P RPP               PP+ P   APS  
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGP 274

Query: 778 AP----SPVGAGTAAPAPSQTP---GSAPPPQAQGPPYP-TYPGYPGYCQMPMPMGYNPY 829
                  P   G   PAP   P   G  PP     PP P  +P  PG    P   G +P 
Sbjct: 275 PGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGV--HPPTSGVHPP 332

Query: 830 AYGQYNMPYPPVYHQSPG-QAPYPGPQQPSYPFPQPPQQSYYPQ 872
           A G  + P P V+  +PG   P PG   P+     PP    +PQ
Sbjct: 333 APG-VHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQ 375



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 719 AREPSAPSIPTPAYQSSP-AGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSAT 777
           A  P AP +  PA    P A G  P PP   P + P   PQPP      V P+N  P   
Sbjct: 385 AVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP-SAPGVHPQPPG-----VHPSN--PGVH 436

Query: 778 APSPVGAGTAAPAPSQTPGSAPPP 801
            P+P+      P PS+ PG+ PPP
Sbjct: 437 PPTPMPPMLRPPLPSEGPGNIPPP 460


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 53/163 (32%), Positives = 61/163 (37%), Gaps = 18/163 (11%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP--PARPPPPVLPANRAPSATAP 779
           P  P  P P +Q          PP   P   PP  PQP    +PPPP   +++   A  P
Sbjct: 56  PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115

Query: 780 SPV-GAGTAAPAPSQTPGSAPP----PQAQGP-PYPTYP-----GYPGYCQMPMPMGYNP 828
            P  G G+A PA S  P + PP    P   GP P PT P       PG      P    P
Sbjct: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP 175

Query: 829 YAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
               Q   P PP     P   P PGP     P P  P+    P
Sbjct: 176 TTPPQAGGPPPP-----PAAVPGPGPGPKQGPGPGGPKGGKMP 213



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 47/148 (31%), Positives = 58/148 (39%), Gaps = 29/148 (19%)

Query: 723 SAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPV 782
           SAP    P   + P  G  PTP      T PP     P   PPP  P++  P+    +P 
Sbjct: 130 SAPPATPPTSGAPPGSGPGPTP------TPPPAVTSAPPGAPPPTPPSSGVPT----TPP 179

Query: 783 GAGTAAPAPSQTPGSAP-PPQAQGPPYP---TYPGYP------------GYCQMPMPMGY 826
            AG   P P+  PG  P P Q  GP  P     PG P            G+ + P   G 
Sbjct: 180 QAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGG 239

Query: 827 NPYAYGQYNMPYPPVYHQSPGQAPYPGP 854
            P    Q++ PY   +HQ P   P  GP
Sbjct: 240 EPRGGRQHHPPYHQQHHQGP---PPGGP 264



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 46/148 (31%), Positives = 56/148 (37%), Gaps = 29/148 (19%)

Query: 738 GGHAPTPPTPAP-----RTMPPTKPQPPARPPPPVLPANRAP-SATAPSPVGAGTAAPAP 791
           G   P PP P P     +  PP +  PP +PPP   P +  P     P P    ++ P  
Sbjct: 52  GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVV 111

Query: 792 SQTP------GSAPPPQAQGPPY--PTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYH 843
           +Q P      GSAPP  +  PP   PT    PG    P P               PP   
Sbjct: 112 AQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP-------------PPAVT 158

Query: 844 QSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
            +P  AP P P  PS   P  P Q+  P
Sbjct: 159 SAPPGAPPPTP--PSSGVPTTPPQAGGP 184



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 20/121 (16%)

Query: 762 RPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAP--PPQAQGPPYPTYPGYPGYCQ 819
           R PPP +  N+      P P  +G   P P   P      PP  Q PP    P       
Sbjct: 32  RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP------H 85

Query: 820 MPMPMGYNPYAYGQYNMPYP------PVYHQSPGQAPYPG---PQQPSYPFPQPPQQSYY 870
            P P   +P  + Q   P P      PV  Q PG AP  G   P   S P   PP     
Sbjct: 86  QPPP---HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAP 142

Query: 871 P 871
           P
Sbjct: 143 P 143


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 62/193 (32%), Positives = 74/193 (38%), Gaps = 48/193 (24%)

Query: 712 KDLQQSIAREPSAPSIPTPA--------------YQSSPAGGHAPTPPTPAPRTMPPTKP 757
           KD+ Q      ++PSIP+P                Q+ P    APT  TPAP + PP  P
Sbjct: 148 KDIDQD--NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 205

Query: 758 QPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPG-----------SAPPPQAQGP 806
           Q P   P         PSATA  P G+ TA+ AP+Q               AP    Q P
Sbjct: 206 QLPTPGP--------TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 257

Query: 807 PYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSP--GQAPYPGPQQ----PSYP 860
           P P  P +P       P+       G    P  P + Q P  GQ P PGP      P   
Sbjct: 258 PSPHPPPHPSPHPPLQPL------TGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQ 310

Query: 861 FPQPPQQSYYPQQ 873
            P PPQ    P Q
Sbjct: 311 HPGPPQPFGLPPQ 323



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/157 (31%), Positives = 54/157 (34%), Gaps = 38/157 (24%)

Query: 731 AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA----PSATAPSPVGAGT 786
           A QS       P PP  AP  MP  KP P    P P LPA +A    P  + PSP     
Sbjct: 352 ALQSQQPPREQPLPP--APLAMPHIKPPPTT--PIPQLPAPQAHKHPPHLSGPSPFSMNA 407

Query: 787 AAPAP-----------SQTPGSAPPP---QAQGPPYPTYPGYPGYCQMPMPMGYNPYAYG 832
             P P              P + PPP     Q  P P+ P  P            P    
Sbjct: 408 NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP------------PGLTQ 455

Query: 833 QYNMPYPPVYHQSPG---QAPYPG-PQQPSYPFPQPP 865
             N+P PP  H   G    AP P   Q P  P   PP
Sbjct: 456 SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 492



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 10/114 (8%)

Query: 725 PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA 784
           P+ P P   +  A  H P    P+P +M    P PPA  P   L  +  PSA  P     
Sbjct: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437

Query: 785 GTAAPAPS---QTPG-----SAPPPQAQGPPYPTY--PGYPGYCQMPMPMGYNP 828
             + P PS   Q PG     + PPP A  PP   +     P + Q P   G  P
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/170 (27%), Positives = 60/170 (35%), Gaps = 26/170 (15%)

Query: 721 EPSAPSIPTP---------AYQSSPAGGHAPTPPTPAPRTMPPT----KPQPPARPPPPV 767
           +P AP+ P P          +   P   H P  P+P P   P T    +P  P+   PP+
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292

Query: 768 LPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQG-PPYPTYP--GYPGYCQMPMPM 824
               + P        G     P P Q P   PP  +QG  P  T P   YP +  + +P 
Sbjct: 293 --HGQGPPGPHSLQAGPLLQHPGPPQ-PFGLPPQASQGQAPLGTSPAAAYP-HTSLQLPA 348

Query: 825 GYNPYAYGQ--YNMPYPPVYHQSPGQAPYPGPQQPSYPFPQ----PPQQS 868
             +     Q     P PP     P   P P    P  P PQ    PP  S
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 17/154 (11%)

Query: 728 PTPAYQ--SSPAGGHAPTPPTPAPRTMPPTKPQP--PARPPPPVLPANRAPSATAPSPVG 783
           P PA +  SS +  H P+   P  + MP ++P P  PA+PP      N  P   +  P G
Sbjct: 411 PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 470

Query: 784 AGTAAPAP-----SQTPGSAPP-PQAQGPPYPTYPGYPGYCQMPMPMG---YNPYAYGQY 834
               AP P        PG  PP      P   T P  PG    P   G         G  
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 530

Query: 835 NMPYPPVYHQ----SPGQAPYPGPQQPSYPFPQP 864
           + P P V  +       + P   P  P  P P+P
Sbjct: 531 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 564



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 24/124 (19%)

Query: 724 APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVG 783
           AP  P   +   P G    TPPT    + PP  P   A+PP        + +A +   + 
Sbjct: 475 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP-------CSGAAASGGSIA 527

Query: 784 AGTAAPAP-----------SQTPGSAPPPQAQGPPYPTYPGYPGYCQMP------MPMGY 826
            G++ P P           ++ P S PPP     P PT    P +          +  GY
Sbjct: 528 GGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGY 587

Query: 827 NPYA 830
           N  A
Sbjct: 588 NSCA 591



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPA--PRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
           P A   P      SP   +A  PP PA  P +   T   P A PPP  L     P  ++P
Sbjct: 388 PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 447

Query: 780 S-PVG---AGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPG 816
           + P G   +    P P+  P +     A  PP+  +P  PG
Sbjct: 448 AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 62/193 (32%), Positives = 74/193 (38%), Gaps = 48/193 (24%)

Query: 712 KDLQQSIAREPSAPSIPTPA--------------YQSSPAGGHAPTPPTPAPRTMPPTKP 757
           KD+ Q      ++PSIP+P                Q+ P    APT  TPAP + PP  P
Sbjct: 702 KDIDQD--NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 758 QPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPG-----------SAPPPQAQGP 806
           Q P   P         PSATA  P G+ TA+ AP+Q               AP    Q P
Sbjct: 760 QLPTPGP--------TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 811

Query: 807 PYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSP--GQAPYPGPQQ----PSYP 860
           P P  P +P       P+       G    P  P + Q P  GQ P PGP      P   
Sbjct: 812 PSPHPPPHPSPHPPLQPL------TGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQ 864

Query: 861 FPQPPQQSYYPQQ 873
            P PPQ    P Q
Sbjct: 865 HPGPPQPFGLPPQ 877



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/157 (31%), Positives = 54/157 (34%), Gaps = 38/157 (24%)

Query: 731  AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA----PSATAPSPVGAGT 786
            A QS       P PP  AP  MP  KP P    P P LPA +A    P  + PSP     
Sbjct: 906  ALQSQQPPREQPLPP--APLAMPHIKPPPTT--PIPQLPAPQAHKHPPHLSGPSPFSMNA 961

Query: 787  AAPAP-----------SQTPGSAPPP---QAQGPPYPTYPGYPGYCQMPMPMGYNPYAYG 832
              P P              P + PPP     Q  P P+ P  P            P    
Sbjct: 962  NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP------------PGLTQ 1009

Query: 833  QYNMPYPPVYHQSPG---QAPYPG-PQQPSYPFPQPP 865
              N+P PP  H   G    AP P   Q P  P   PP
Sbjct: 1010 SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 10/114 (8%)

Query: 725  PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA 784
            P+ P P   +  A  H P    P+P +M    P PPA  P   L  +  PSA  P     
Sbjct: 932  PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991

Query: 785  GTAAPAPS---QTPG-----SAPPPQAQGPPYPTY--PGYPGYCQMPMPMGYNP 828
              + P PS   Q PG     + PPP A  PP   +     P + Q P   G  P
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/170 (27%), Positives = 60/170 (35%), Gaps = 26/170 (15%)

Query: 721 EPSAPSIPTP---------AYQSSPAGGHAPTPPTPAPRTMPPT----KPQPPARPPPPV 767
           +P AP+ P P          +   P   H P  P+P P   P T    +P  P+   PP+
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846

Query: 768 LPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQG-PPYPTYP--GYPGYCQMPMPM 824
               + P        G     P P Q P   PP  +QG  P  T P   YP +  + +P 
Sbjct: 847 --HGQGPPGPHSLQAGPLLQHPGPPQ-PFGLPPQASQGQAPLGTSPAAAYP-HTSLQLPA 902

Query: 825 GYNPYAYGQ--YNMPYPPVYHQSPGQAPYPGPQQPSYPFPQ----PPQQS 868
             +     Q     P PP     P   P P    P  P PQ    PP  S
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 17/154 (11%)

Query: 728  PTPAYQ--SSPAGGHAPTPPTPAPRTMPPTKPQP--PARPPPPVLPANRAPSATAPSPVG 783
            P PA +  SS +  H P+   P  + MP ++P P  PA+PP      N  P   +  P G
Sbjct: 965  PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 784  AGTAAPAP-----SQTPGSAPP-PQAQGPPYPTYPGYPGYCQMPMPMG---YNPYAYGQY 834
                AP P        PG  PP      P   T P  PG    P   G         G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 1084

Query: 835  NMPYPPVYHQ----SPGQAPYPGPQQPSYPFPQP 864
            + P P V  +       + P   P  P  P P+P
Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 24/124 (19%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVG 783
            AP  P   +   P G    TPPT    + PP  P   A+PP        + +A +   + 
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP-------CSGAAASGGSIA 1081

Query: 784  AGTAAPAP-----------SQTPGSAPPPQAQGPPYPTYPGYPGYCQMP------MPMGY 826
             G++ P P           ++ P S PPP     P PT    P +          +  GY
Sbjct: 1082 GGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGY 1141

Query: 827  NPYA 830
            N  A
Sbjct: 1142 NSCA 1145



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPA--PRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
            P A   P      SP   +A  PP PA  P +   T   P A PPP  L     P  ++P
Sbjct: 942  PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001

Query: 780  S-PVG---AGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPG 816
            + P G   +    P P+  P +     A  PP+  +P  PG
Sbjct: 1002 AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 62/193 (32%), Positives = 74/193 (38%), Gaps = 48/193 (24%)

Query: 712 KDLQQSIAREPSAPSIPTPA--------------YQSSPAGGHAPTPPTPAPRTMPPTKP 757
           KD+ Q      ++PSIP+P                Q+ P    APT  TPAP + PP  P
Sbjct: 702 KDIDQD--NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 758 QPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPG-----------SAPPPQAQGP 806
           Q P   P         PSATA  P G+ TA+ AP+Q               AP    Q P
Sbjct: 760 QLPTPGP--------TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 811

Query: 807 PYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSP--GQAPYPGPQQ----PSYP 860
           P P  P +P       P+       G    P  P + Q P  GQ P PGP      P   
Sbjct: 812 PSPHPPPHPSPHPPLQPL------TGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQ 864

Query: 861 FPQPPQQSYYPQQ 873
            P PPQ    P Q
Sbjct: 865 HPGPPQPFGLPPQ 877



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/157 (31%), Positives = 54/157 (34%), Gaps = 38/157 (24%)

Query: 731  AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA----PSATAPSPVGAGT 786
            A QS       P PP  AP  MP  KP P    P P LPA +A    P  + PSP     
Sbjct: 906  ALQSQQPPREQPLPP--APLAMPHIKPPPTT--PIPQLPAPQAHKHPPHLSGPSPFSMNA 961

Query: 787  AAPAP-----------SQTPGSAPPP---QAQGPPYPTYPGYPGYCQMPMPMGYNPYAYG 832
              P P              P + PPP     Q  P P+ P  P            P    
Sbjct: 962  NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP------------PGLTQ 1009

Query: 833  QYNMPYPPVYHQSPG---QAPYPG-PQQPSYPFPQPP 865
              N+P PP  H   G    AP P   Q P  P   PP
Sbjct: 1010 SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 10/114 (8%)

Query: 725  PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA 784
            P+ P P   +  A  H P    P+P +M    P PPA  P   L  +  PSA  P     
Sbjct: 932  PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991

Query: 785  GTAAPAPS---QTPG-----SAPPPQAQGPPYPTY--PGYPGYCQMPMPMGYNP 828
              + P PS   Q PG     + PPP A  PP   +     P + Q P   G  P
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/170 (27%), Positives = 60/170 (35%), Gaps = 26/170 (15%)

Query: 721 EPSAPSIPTP---------AYQSSPAGGHAPTPPTPAPRTMPPT----KPQPPARPPPPV 767
           +P AP+ P P          +   P   H P  P+P P   P T    +P  P+   PP+
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846

Query: 768 LPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQG-PPYPTYP--GYPGYCQMPMPM 824
               + P        G     P P Q P   PP  +QG  P  T P   YP +  + +P 
Sbjct: 847 --HGQGPPGPHSLQAGPLLQHPGPPQ-PFGLPPQASQGQAPLGTSPAAAYP-HTSLQLPA 902

Query: 825 GYNPYAYGQ--YNMPYPPVYHQSPGQAPYPGPQQPSYPFPQ----PPQQS 868
             +     Q     P PP     P   P P    P  P PQ    PP  S
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 17/154 (11%)

Query: 728  PTPAYQ--SSPAGGHAPTPPTPAPRTMPPTKPQP--PARPPPPVLPANRAPSATAPSPVG 783
            P PA +  SS +  H P+   P  + MP ++P P  PA+PP      N  P   +  P G
Sbjct: 965  PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 784  AGTAAPAP-----SQTPGSAPP-PQAQGPPYPTYPGYPGYCQMPMPMG---YNPYAYGQY 834
                AP P        PG  PP      P   T P  PG    P   G         G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 1084

Query: 835  NMPYPPVYHQ----SPGQAPYPGPQQPSYPFPQP 864
            + P P V  +       + P   P  P  P P+P
Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 24/124 (19%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVG 783
            AP  P   +   P G    TPPT    + PP  P   A+PP        + +A +   + 
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP-------CSGAAASGGSIA 1081

Query: 784  AGTAAPAP-----------SQTPGSAPPPQAQGPPYPTYPGYPGYCQMP------MPMGY 826
             G++ P P           ++ P S PPP     P PT    P +          +  GY
Sbjct: 1082 GGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGY 1141

Query: 827  NPYA 830
            N  A
Sbjct: 1142 NSCA 1145



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPA--PRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
            P A   P      SP   +A  PP PA  P +   T   P A PPP  L     P  ++P
Sbjct: 942  PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001

Query: 780  S-PVG---AGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPG 816
            + P G   +    P P+  P +     A  PP+  +P  PG
Sbjct: 1002 AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 51/163 (31%), Positives = 64/163 (39%), Gaps = 23/163 (14%)

Query: 716 QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPP---PPVLPANR 772
           Q  A  P  PS P P   S  +G   P P  P P + PP     P  PP   PP +P   
Sbjct: 209 QLFADAPPPPSAPNPVVSSLGSG--LPPPGMPPPGSFPP-----PVPPPGALPPGIPPAM 261

Query: 773 APSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPG---YPGYCQMPMPMGYNPY 829
            P    P P GA    P  + TPG+  P      P+P  PG   +PG  QM +       
Sbjct: 262 PP---PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA------ 312

Query: 830 AYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQ 872
            +G + + +P       G  P P P  P  P P PP     P+
Sbjct: 313 HHGPHGLGHPHAGPPGSGGQPPPRP-PPGMPHPGPPPMGMPPR 354



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 15/132 (11%)

Query: 727 IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGT 786
           +P P         H P          P +  QPP RPPP +      P    P     G 
Sbjct: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPR----GP 356

Query: 787 AAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNM------PYPP 840
              +P   PG  PP   +GPP P  P + GY   P P    PY Y +  +      P PP
Sbjct: 357 PFGSPMGHPGPMPPHGMRGPP-PLMPPH-GYTGPPRP---PPYGYQRGPLPPPRPTPRPP 411

Query: 841 VYHQSPGQAPYP 852
           V  + P + P P
Sbjct: 412 VPPRGPLRGPLP 423



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 14/104 (13%)

Query: 765 PPVLPANRAPSATAPSPV--GAGTAAPAPSQ-TPGSAPPPQAQGPPYPTYPGY-PGYCQM 820
           P  L A+  P  +AP+PV    G+  P P    PGS PPP    PP    PG  P     
Sbjct: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVP--PPGALPPGIPPAMPPP 264

Query: 821 PMP---MGYNPYAYGQYNMPYPPVYHQ-----SPGQAPYPGPQQ 856
           PMP    G+ P + G     +P   H       PG  P+PG  Q
Sbjct: 265 PMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQ 308



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 3/82 (3%)

Query: 725 PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA 784
           P +P P     P G     PP  +P   P   P    R PPP++P +       P P G 
Sbjct: 339 PGMPHPG--PPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGY 396

Query: 785 GTAAPAPSQTPGSAPPPQAQGP 806
               P P   P   PP   +GP
Sbjct: 397 -QRGPLPPPRPTPRPPVPPRGP 417


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 51/150 (34%), Positives = 57/150 (38%), Gaps = 18/150 (12%)

Query: 720 REPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAP 779
           R  + P  P  A + +PA   A  PP   P   PP  P P A   P   P   A +ATAP
Sbjct: 103 RRGATPPAPPRAPRGAPAAAAAAAPP---PTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159

Query: 780 SPVGAGTAAP-APSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPY 838
              G     P A    P +APPP    PP    P  P     P      P        P 
Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREP--------PL 211

Query: 839 PPVYHQSPGQAPY-PGPQQPSYPFPQPPQQ 867
           PP     P Q P  P  QQP  P PQPP +
Sbjct: 212 PP-----PPQPPAPPQQQQPPPPQPQPPPE 236



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 33/91 (36%), Positives = 38/91 (41%), Gaps = 13/91 (14%)

Query: 719 AREPSAPSIPTPAYQSSPAGGHAPTPPTPA--PRTMPPTKPQPPARPPPPVLPANRAPSA 776
           A  P +P    P  ++  A   A  PP PA  P   PP  P+   R PPP + A   P  
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR---RAPPPAVAAREPPLP 212

Query: 777 TAPSPVGAGTAAPAPSQTPGSAPPPQAQGPP 807
             P P       PAP Q     PPPQ Q PP
Sbjct: 213 PPPQP-------PAPPQQQ-QPPPPQPQPPP 235



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 26/57 (45%), Positives = 29/57 (50%), Gaps = 7/57 (12%)

Query: 718 IAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMP-PTKPQPPARP----PPPVLP 769
           +A  P AP+ P PA  + PAG     PP  A R  P P  PQPPA P    PPP  P
Sbjct: 177 LAAPPPAPAAP-PAV-APPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQP 231



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 3/57 (5%)

Query: 725 PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTK--PQPPARPPPPVLPANRAPSATAP 779
           P+ P  A   + A    P PP P P   PP +  P PP   PPP   A RA  A  P
Sbjct: 193 PAGPRRAPPPAVAAREPPLPPPPQPPA-PPQQQQPPPPQPQPPPEGGAVRAGGAARP 248


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 57/166 (34%), Positives = 63/166 (37%), Gaps = 31/166 (18%)

Query: 722  PSAPSIP-TPAYQSSPAGGHAPTPPTPAPRTMPPTKP-----QPPAR-------PPPPVL 768
            PS P +P T +  S P  G  P PP P P    PT P     QPP         PPPP L
Sbjct: 856  PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915

Query: 769  PANRAP-------SATAPSPVGAGTAAPAPSQTPGSA--PPPQAQGPPYPTYPGYPGYCQ 819
            P    P       +   P P   G   P P   PG+A  PPP   G   P  P  PG   
Sbjct: 916  PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG-AG 974

Query: 820  MPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
            +P P    P   G    P PP+    PG    P P  P    P PP
Sbjct: 975  IPPP----PPLPGAGIPPPPPL----PGAGIPPPPPLPGAGIPPPP 1012



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 53/151 (35%), Positives = 58/151 (38%), Gaps = 15/151 (9%)

Query: 717  SIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPS 775
            +I   P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P 
Sbjct: 952  AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIP- 1009

Query: 776  ATAPSPV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQY 834
               P P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G  
Sbjct: 1010 --PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPP----PPLPGAG 1062

Query: 835  NMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
              P PP+    PG    P P  P    P PP
Sbjct: 1063 IPPPPPL----PGAGIPPPPPLPGAGIPPPP 1089



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 52/146 (35%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS 780
            P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P    P 
Sbjct: 979  PPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPP---PP 1034

Query: 781  PV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYP 839
            P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G    P P
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPP----PPLPGAGIPPPP 1089

Query: 840  PVYHQSPGQAPYPGPQQPSYPFPQPP 865
            P+    PG    P P  P    P PP
Sbjct: 1090 PL----PGAGIPPPPPLPGVGIPPPP 1111



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 52/146 (35%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS 780
            P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P    P 
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPP---PP 1067

Query: 781  PV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYP 839
            P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G    P P
Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-VGIPPP----PPLPGAGIPPPP 1122

Query: 840  PVYHQSPGQAPYPGPQQPSYPFPQPP 865
            P+    PG    P P  P    P PP
Sbjct: 1123 PL----PGAGIPPPPPLPGAGIPPPP 1144



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 52/146 (35%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS 780
            P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P    P 
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVG-IPPPPPLPGAGIPPPPPLPGAGIPP---PP 1133

Query: 781  PV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYP 839
            P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G    P P
Sbjct: 1134 PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG-AGIPPP----PPLPGVGIPPPP 1188

Query: 840  PVYHQSPGQAPYPGPQQPSYPFPQPP 865
            P+    PG    P P  P    P PP
Sbjct: 1189 PL----PGVGIPPPPPLPGAGIPPPP 1210



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 51/146 (34%), Positives = 55/146 (37%), Gaps = 15/146 (10%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS 780
            P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P    P 
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGVGIPP---PP 1111

Query: 781  PV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYP 839
            P+ GAG   P P    G  PPP   G   P  P  P    +P P    P   G    P P
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-RVGIPPP----PPLPGAGIPPPP 1166

Query: 840  PVYHQSPGQAPYPGPQQPSYPFPQPP 865
            P+    PG    P P  P    P PP
Sbjct: 1167 PL----PGAGIPPPPPLPGVGIPPPP 1188



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 52/153 (33%), Positives = 57/153 (37%), Gaps = 21/153 (13%)

Query: 722  PSAPSIPTPAYQSS------PAGGHAPTPPTPAPRTMPPTKPQPPAR--PPPPVLPANRA 773
            P A  +P P    +      P  G A  PP P P    P  P  P    PPPP LP    
Sbjct: 927  PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGI 986

Query: 774  PSATAPSPV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYG 832
            P    P P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G
Sbjct: 987  P---PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPP----PPLPG 1038

Query: 833  QYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
                P PP+    PG    P P  P    P PP
Sbjct: 1039 AGIPPPPPL----PGAGIPPPPPLPGAGIPPPP 1067



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 41/107 (38%), Positives = 44/107 (41%), Gaps = 5/107 (4%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS 780
            P  P    P     P  G  P PP P    +PP  P P A  PPPP LP    P A AP 
Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPGVG-IPPPPPLPGAGIPPPPPLPGMGIPPAPAPP 1224

Query: 781  PVGAGTAAPAPSQTPGSAPP--PQAQGPPYPTYPGYPGYCQMPMPMG 825
                GT  P P   P S PP  PQ      PT P   G+   P+P G
Sbjct: 1225 LPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT-PQVCGFLPPPLPSG 1270



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 51/147 (34%), Positives = 56/147 (38%), Gaps = 13/147 (8%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRT-MPPTKPQPPAR-PPPPVLPANRAPSATAP 779
            P  P +  P     P  G  P  P P P   +PP  P P A  PPPP LP    P    P
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP---PP 1154

Query: 780  SPV-GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPY 838
             P+ GAG   P P    G  PPP   G   P  P  PG   +P P    P   G    P 
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-VGIPPP----PPLPGAGIPPP 1209

Query: 839  PPVYHQSPGQAPYPGPQQPSYPFPQPP 865
            PP+       AP P    P    P PP
Sbjct: 1210 PPLPGMGIPPAPAPPLPPPGTGIPPPP 1236



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 51/148 (34%), Positives = 56/148 (37%), Gaps = 15/148 (10%)

Query: 727  IPTPAYQSSPAGGHAPTPPTPAPRT-MPPTKPQPPAR-PPPPVLPANRAPSATAPSPV-G 783
            IP P     P  G    PP P PR  +PP  P P A  PPPP LP    P    P P+ G
Sbjct: 1129 IPPPP----PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPG 1181

Query: 784  AGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYH 843
             G   P P    G  PPP   G   P  P  PG    P P    P       +P PP+  
Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA--PPLPPPGTGIPPPPLL- 1238

Query: 844  QSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
              P   P   PQ  S   P P    + P
Sbjct: 1239 --PVSGPPLLPQVGSSTLPTPQVCGFLP 1264



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 60/260 (23%), Positives = 96/260 (36%), Gaps = 60/260 (23%)

Query: 594 AQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANL 653
           +++ V++ +AL   ELD  +  LT     SL   E  L + + +             A  
Sbjct: 93  SREDVLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPGPAEA 152

Query: 654 REEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKD 713
           R   +     A D  VE  A  ++G +  +     +  F +          TE+++LL D
Sbjct: 153 R---VGGRPIAED--VETAAGAQDGQRTSSGSDTDIYSFHSA---------TEQEDLLSD 198

Query: 714 LQQSI-------------------------AREPSAPSI---PTPA-------YQSSPAG 738
           +QQ+I                         A EP+AP     P P        +   P+G
Sbjct: 199 IQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSG 258

Query: 739 GHAPTPPTP-------APRTMPPT---KPQPPARPPPPV-LPANRAPSATAPSPVGAGTA 787
           G    P +P       A   +P +   +P+ P +PP P  LP + APS  A  P    + 
Sbjct: 259 GAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSP 318

Query: 788 APAPSQTPGSAPPPQAQGPP 807
           +      P + P  +A G P
Sbjct: 319 SSTAFPFPEAGPGEEAAGAP 338



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 40/183 (21%)

Query: 711 LKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPA-PRTMPPTKPQPP--ARPPPPV 767
           L DL +S+A EP  P  P       P+ G  P    P+ P   P  K  P   A P P  
Sbjct: 276 LSDLPESLAAEPREPQQP-------PSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEA 328

Query: 768 LPANRAPSATA----------------PSPVGAGTAAPAPS------QTPGSAPPPQAQG 805
            P   A  A                   +P G+     AP       Q  G  P  +AQG
Sbjct: 329 GPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQG 388

Query: 806 PPYPTYPGYPG------YCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSY 859
           P  P     PG       C  P P+    Y          P  + SP Q+P   P+    
Sbjct: 389 PDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSP--NHSPSQSPNQSPRIKRR 446

Query: 860 PFP 862
           P P
Sbjct: 447 PEP 449


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 57/156 (36%), Positives = 65/156 (41%), Gaps = 22/156 (14%)

Query: 722 PSAPS-----IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP-PARPPPPVLPANRAPS 775
           PSAPS     +P  A  S+   G APT   P+   +PPT P P P  P PP  P+   P 
Sbjct: 43  PSAPSSVPSGLPPSATPSTVPFGPAPTGMYPS---VPPTGPPPGPPAPFPPSGPSCPPPG 99

Query: 776 ATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYA---YG 832
              P+P   G     P  TP    P   +    PT P   G       M   P+A    G
Sbjct: 100 GPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGG 159

Query: 833 QY---NMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
           QY   NMPYP     SPG  PYP P  P  P   PP
Sbjct: 160 QYPTPNMPYP-----SPG--PYPAPPPPQAPGAAPP 188



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 49/154 (31%), Positives = 55/154 (35%), Gaps = 17/154 (11%)

Query: 722 PSAPSIPTPA--YQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP---SA 776
           PS PS P P   Y +    G  PT P P P    P  P+P   P  P       P    +
Sbjct: 90  PSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMS 149

Query: 777 TAPSPVGAGTAAPAPSQT-PGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYN 835
           + P   G G   P P+   P   P P    PP P  PG       P+P G  P       
Sbjct: 150 SGPWAPGMGGQYPTPNMPYPSPGPYP---APPPPQAPG----AAPPVPWGTVPPGAWGPP 202

Query: 836 MPYPPVYHQSPGQAPYPGP----QQPSYPFPQPP 865
            PYP      P    YP P    Q PS P   PP
Sbjct: 203 APYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPP 236



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 38/119 (31%), Positives = 44/119 (36%), Gaps = 24/119 (20%)

Query: 718 IAREPSAPSIPTPAYQSSP------------AGGHAPTP----PTPAPRTMPPTKPQPPA 761
           + R   AP+ P  A    P             GG  PTP    P+P P   PP    P A
Sbjct: 126 LPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGA 185

Query: 762 RPPPP---VLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPP--YPTYPGYP 815
            PP P   V P    P A  P+P G   + P P   P  + P Q    P   P  PG P
Sbjct: 186 APPVPWGTVPPGAWGPPAPYPAPTG---SYPTPGLYPTPSNPFQVPSGPSGAPPMPGGP 241



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 9/95 (9%)

Query: 738 GGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGA-GTAAPAPSQTPG 796
           GG  PTP  P P       P P   PPPP  P    P      P GA G  AP P+ T G
Sbjct: 158 GGQYPTPNMPYP------SPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPT-G 210

Query: 797 SAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAY 831
           S P P     P   +    G    P PM   P++Y
Sbjct: 211 SYPTPGLYPTPSNPFQVPSGPSGAP-PMPGGPHSY 244


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 62/213 (29%), Positives = 83/213 (38%), Gaps = 39/213 (18%)

Query: 690 VRFQNKCSDI---VFARKTERDELLKDLQQSIAREPSA---PSIPTPAYQSSPAGGHAPT 743
           VR Q+  S +    + R T+ +E  K   +S+ R  ++   P  P P   + P     P+
Sbjct: 567 VRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVT-PYTASQPS 625

Query: 744 PPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPV-----------------GAGT 786
           PP P P   PP  P PP  PPPP LP+  APSA + +P+                 GA  
Sbjct: 626 PPLPPPPPPPPPPPPPPP-PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684

Query: 787 AAPAPSQTPGSAPPPQ--------AQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPY 838
             P P      +  PQ           PP P  P  PG     +       +  Q++ P 
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP 744

Query: 839 PP-----VYHQSPGQAPYPGPQQPSYPFPQPPQ 866
           PP     V H +    P P P  P  P P PPQ
Sbjct: 745 PPLKIHQVQHITQVAPPTP-PPPPPIPAPLPPQ 776



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 48/155 (30%), Positives = 56/155 (36%), Gaps = 24/155 (15%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSP 781
           P APS+P  +    P   H     T   +  PPT P PP  P P    A   P  T P+P
Sbjct: 732 PCAPSLPQFSAPPPPLKIHQVQHIT---QVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788

Query: 782 VGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP- 840
               T AP  +Q            PP PT P  P   Q   P  Y P +     +P PP 
Sbjct: 789 TSTKTVAPVVTQA----------APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPP 838

Query: 841 --VYHQSPGQAPYPGPQQP--------SYPFPQPP 865
                QS    P P P  P        +  FP PP
Sbjct: 839 TLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP 873



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 46/158 (29%), Positives = 60/158 (37%), Gaps = 24/158 (15%)

Query: 717 SIAREPSAPSIPTPAYQSSPAGGHAPTPPT---PA--PRTMPPTKPQPPARPPPPVLPAN 771
           +I    S  ++     Q++P     P PP    PA     +PP+ P PP   PPP LP  
Sbjct: 784 TIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQ 843

Query: 772 RAPSATAPSPVGAGTAAPAP-SQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYA 830
           ++  A  P         P+P S  P       +Q PP PT P        P+P    P +
Sbjct: 844 QSFCAKPP---------PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894

Query: 831 YGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
                   PP     P   P   P  PS  FP PP +S
Sbjct: 895 --------PPAVKAKPKWQPSSIP-VPSPDFPPPPPES 923



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 25/169 (14%)

Query: 716 QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP---ARPPP-PVLP-- 769
           Q+    P+ P  P     + PA    P+PPTP     PPT P+     A+PPP P+ P  
Sbjct: 800 QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP 859

Query: 770 ------ANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMP 823
                 A++ P    P  + +    P P+     +PP     P +           +P+P
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP-------SSIPVP 912

Query: 824 MGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQP-PQQSYYP 871
               P    + ++ +PP     P  +P P P  P  P   P P +S  P
Sbjct: 913 SPDFPPPPPESSLVFPP-----PPPSPVPAPPPPPPPTASPTPDKSGSP 956



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 47/161 (29%), Positives = 58/161 (36%), Gaps = 25/161 (15%)

Query: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPP--PPVLPANR 772
           Q   A+ P +P  P P+     A    P PPTP      P KP P    P  PP + A  
Sbjct: 844 QSFCAKPPPSPLSPVPSVVKQIAS-QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP 902

Query: 773 --------APSATAPSPVGAGTAA-----PAPSQTPGSAPPPQAQGPPYPTYPGYPG--Y 817
                    PS   P P    +       P+P   P   PPP A   P P   G PG   
Sbjct: 903 KWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS--PTPDKSGSPGKKT 960

Query: 818 CQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPS 858
            +   P G  P    Q N        +S   A +P P++PS
Sbjct: 961 SKTSSPGGKKPPPTPQRNSSI-----KSSSGAEHPEPKRPS 996



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 38/152 (25%), Positives = 55/152 (36%), Gaps = 9/152 (5%)

Query: 711  LKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPA 770
            LK +  ++A +        P +Q S     +P  P P P +     P PP+  P P  P 
Sbjct: 883  LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP- 941

Query: 771  NRAPSATAPSPVGAGTAAPAPSQT--PGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNP 828
               P   +P+P  +G+     S+T  PG   PP    P   +        + P P    P
Sbjct: 942  --PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT--PQRNSSIKSSSGAEHPEPK--RP 995

Query: 829  YAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYP 860
                  +   PP    SP +   P P  P  P
Sbjct: 996  SVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 18/48 (37%), Positives = 19/48 (39%), Gaps = 5/48 (10%)

Query: 821 PMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
           P P    PY   Q + P PP     P   P P P  P  P P  P QS
Sbjct: 611 PQPKIVTPYTASQPSPPLPP-----PPPPPPPPPPPPPPPPPPLPSQS 653


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 55/161 (34%), Positives = 64/161 (39%), Gaps = 21/161 (13%)

Query: 725 PSIPTPAYQSSPAG---GHAPTPPTPAP----------RTMPPTKPQPPARPPPPVLPAN 771
           PS+  P  Q++ A     H  TPP PAP           T PP  P   A PPP   PA 
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598

Query: 772 RAPSATA-PSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQM--PMPMGYNP 828
            +P     PSP  +  A P P   P  A PP  Q PP P  P  P    +  P P   N 
Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-LQAPPSP--PASPPLSPLATPSPQAPNA 655

Query: 829 YAYGQYNMPYPPVYHQSPGQAPYPGPQQPSY-PFPQPPQQS 868
            A      P+ P     P QAP+  P  P   P   PP Q+
Sbjct: 656 LAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQA 695



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 56/173 (32%), Positives = 70/173 (40%), Gaps = 20/173 (11%)

Query: 714 LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTM--PPTK--PQPPARPP--PPV 767
           LQ   +  PS P     +  +SP    + TPP+ AP ++  PP +  P PPA PP  P  
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720

Query: 768 LPANRAPSATAPSPVGAGTAAPA-----PSQTPGSAPPPQAQGPPYPTYPGYPGYCQM-- 820
            P  +AP   A  P+    + PA     PS TP    PP    PP    P  P    M  
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780

Query: 821 ---PMPMGYNPYAYGQYN-MPYPPVYHQSPGQAPY-PGPQQPSYPFPQPPQQS 868
              P P      A      +P PP     PGQAP+ P    P  P   PP Q+
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPA--SFPGQAPFSPSASLPMSPLATPPPQA 831



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 51/165 (30%), Positives = 63/165 (38%), Gaps = 28/165 (16%)

Query: 722 PSAPSIP------TPAYQSSPAGG----HAPTPPTPAPRTMPPTKPQPPARPP--PPVLP 769
           PS P+ P      TP+ Q+  A       AP  P P+P    P  P  PA PP  P   P
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--PASPPVSPSATP 691

Query: 770 ANRAPSATAPSPVGAGTAAPA-----PSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPM 824
            ++AP + A  P+    + PA     PS TP    PP    PP    P  P     PM  
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP--ASPPMSP 749

Query: 825 GYNPYAYGQYNMPYPPVYHQSPGQA-PYPGPQQPSYPFPQPPQQS 868
              P          PP+    P Q  P P    P  P  +PP Q+
Sbjct: 750 SATP------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/177 (30%), Positives = 67/177 (37%), Gaps = 32/177 (18%)

Query: 717 SIAREP--SAPSIPTPAYQSSPAGGHAP--TPPTPAPRTMP-PTKPQPPARPPPPVLPAN 771
           SIA  P  + P++ +P  Q  P+   +P  TPP  AP  +  P    PP+ P  P L   
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 772 RAPSATAPS-----------------PVGAGTAAPA-----PSQTPGSAPPPQAQGPPYP 809
             PS  AP+                 PV A  + PA     PS TP S  PP    PP  
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705

Query: 810 TYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPS-YPFPQPP 865
             P  P     PM     P       +  PP+  Q P   P   P  PS  P P+ P
Sbjct: 706 VPPSPP--ASPPMSPSATPPPQAPPPLAAPPL--QVPPSPPASPPMSPSATPPPRVP 758



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 28/129 (21%)

Query: 709 ELLKDLQQSIAREPSAPSI----PTPAYQSSPAGGHA-PTPP-----TPAPRTMPPTKP- 757
           + L+  Q +  R+ +AP++     +P    SP+G  A P PP     TP P T+PP+ P 
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 758 ------QPPARPPPPVLPANRAPSATAPSPVGAGTAAP-----------APSQTPGSAPP 800
                  PP+   PP L    +P AT PS        P            P Q P S   
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 801 PQAQGPPYP 809
           P  Q PP P
Sbjct: 398 PSLQAPPSP 406



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 45/174 (25%), Positives = 56/174 (32%), Gaps = 26/174 (14%)

Query: 714 LQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA 773
           L     R+ S P+  TP+   +     A T     PR  P  +P+PP   P   + +   
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTE-VGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 774 PSATAPSP-------VGAGTAAPAPSQTPGSAPP---PQAQGPPYPTYPGYPGYCQMPMP 823
            S T PSP        G G   PA      SA P   P   GP     P  P +   P P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 824 MGYNPYAYGQYNMP------------YPPVYHQSPG---QAPYPGPQQPSYPFP 862
            G       Q   P              P+   SP      P P P   + P P
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 49/176 (27%), Positives = 61/176 (34%), Gaps = 32/176 (18%)

Query: 711 LKDLQQSIAREPSAPS----IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPP 766
           L+ L    +  P AP     +P    QSS A     TPP  A  T PP +  P   PPP 
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP--ASLTTPPLENLPSLAPPP- 545

Query: 767 VLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPP----------------PQAQGPPYPT 810
                   +A+AP         P P+  P  APP                P  Q PP   
Sbjct: 546 ------LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599

Query: 811 YPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQP-SYPFPQPP 865
            P   G    P+     P       +  PP+  Q+P   P   P  P + P PQ P
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPL--QAPPSPPASPPLSPLATPSPQAP 653



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 46/151 (30%), Positives = 58/151 (38%), Gaps = 44/151 (29%)

Query: 722 PSAPSIPTPAYQSSPAGGHAP---TPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATA 778
           PS P+ P  +  ++P     P    PP   P + P + P  P   PPP     +AP A A
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP-----QAPPALA 793

Query: 779 PSPVGAGTAAPA--PSQTPGS-----------APPPQAQGPPYPTYPGYPGYCQMPMPMG 825
             P+ A  + PA  P Q P S            PPPQA  PP    P      Q+P    
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA--PPVLAAP----LLQVP---- 843

Query: 826 YNPYAYGQYNMPYPPVYH--QSPGQAPYPGP 854
                      P PP     Q+P + P PGP
Sbjct: 844 -----------PSPPASPTLQAPRRPPTPGP 863



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 36/174 (20%)

Query: 728 PTPAYQSSPAGG------------HAPTPPTPAPRTMP-----PTKPQPPARPPPPVLPA 770
           P+PA +  P+ G             + TP +   R+ P     P  P  P++P P  L A
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279

Query: 771 NRAPSATAP--------SPVGAG-TAAPAPSQTPG-SAPPPQAQGPPYP-TYPGYPGYCQ 819
            R P  T P         P+ +   A P+PS T     PPP     P P T P  P    
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA- 338

Query: 820 MPMPMG-YNPYA-YGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
            P+P+   +P A      +P PP     P QAP   P   + P   PP     P
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPA--TPPSQAP---PSMTTPPMQAPPSLQTIP 387



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/154 (30%), Positives = 59/154 (38%), Gaps = 20/154 (12%)

Query: 720 REPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLP-ANRAPSAT- 777
           R P+ PS      Q  P G  A  P    P+  PP K   PA  P    P A  +PS T 
Sbjct: 264 RAPAHPS------QPKPKGLQALRP----PQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 778 -APSPVGAGTAAPAPSQTPGSAP--PPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQY 834
             P P     A P P+  P S P   P    PP P+ P  P    +P P    P +    
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP--PSLQTLPSPPA-TPPSQAPP 370

Query: 835 NMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
           +M  PP+  Q+P       P Q  +    P  Q+
Sbjct: 371 SMTTPPM--QAPPSLQTIPPIQVPHSLTSPSLQA 402



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 34/104 (32%), Positives = 39/104 (37%), Gaps = 28/104 (26%)

Query: 737 AGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPA-----------NRAPSATAPSPVGAG 785
           AG  A TP   AP  + P  P  P RPPPPV PA            R P A     +G  
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 786 T------------AAPAPSQTPGSAPPPQAQG----PPYPTYPG 813
           T            +A   S+ P S PP   +G    P   T PG
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 33/139 (23%)

Query: 722 PSAPSI-PTPAYQSSPAGGHAPT------PPTPAPRT----------MPPTKPQPPARPP 764
           P AP +   P  Q  P+   +PT      PPTP P T          + P  P PP+R P
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888

Query: 765 PPVLP----ANRAPSATA---------PSPVGAGTAAPAP-SQTPGSAPPPQAQGPPYP- 809
              L     A  + SAT+           P G   A+P P ++     P   ++GP  P 
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948

Query: 810 TYPGYPGYCQMPMPMGYNP 828
            + G PG   +P P    P
Sbjct: 949 AFRGAPG-APLPWPPATGP 966



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 40/151 (26%), Positives = 52/151 (34%), Gaps = 20/151 (13%)

Query: 734 SSPAGGHAPTPPTPAPRTMPPTKP--------QPPARPPPPVLPANRAPSATAPSP-VGA 784
           S PA     +PP  AP ++P + P          P   P  + P     S  + SP    
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504

Query: 785 GTAAPAPSQTPGSAPPPQAQGPP----YPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP 840
            +    P +T  S  PP  Q PP     P     P     P+     P      ++  PP
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT--TPHLETPP 562

Query: 841 VYHQSPGQAP-----YPGPQQPSYPFPQPPQ 866
                P QAP      P P+ PS     PPQ
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 26/115 (22%)

Query: 718 IAREP--SAPSIPTPAYQSSPAG-----GHAPTPP----------TPAPRTMP----PTK 756
           +A+ P  + P++ TP  Q+ P+      G AP  P          TP P+  P    P  
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 757 PQPPARPPPPVLPANRAPSATAPSPVGAG-----TAAPAPSQTPGSAPPPQAQGP 806
             PP+ P  P L A R P    P    +G       AP P   P  +P     GP
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 39/138 (28%), Positives = 53/138 (38%), Gaps = 32/138 (23%)

Query: 722 PSAPSIPTP-AYQSSPAGGHAPTPPTPAP---RTMPP-------TKPQPPARPPP----- 765
           PS  ++P+P A   S A     TPP  AP   +T+PP       T P   A P P     
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411

Query: 766 ---------PVLPANRAPSATAPSPVGAGTAAPA-PSQTPGSAPPPQA-----QGPPYPT 810
                    P L A  +    +P    A   +P+ P+ TP  +PP QA       PP  T
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471

Query: 811 YPGYPGYCQMPMPMGYNP 828
               P    +  P+  +P
Sbjct: 472 SLS-PAVSPLSSPLTIHP 488



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 31/97 (31%), Positives = 37/97 (38%), Gaps = 22/97 (22%)

Query: 723 SAPSIPTP--AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS 780
           SA S P     Y S P GG A +PP  A   +    P   +R P P L    AP A  P 
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSRGPAPPLAFRGAPGAPLPW 960

Query: 781 PVGAG-----------------TAAPAP-SQTPGSAP 799
           P   G                 +A PAP +  PG +P
Sbjct: 961 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 1/82 (1%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSP 781
           P +PS P P+ Q+ P+    P    P   T PP +  P  +  PP+   +   S +  +P
Sbjct: 345 PPSPSAP-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403

Query: 782 VGAGTAAPAPSQTPGSAPPPQA 803
                 +   + T   +P  QA
Sbjct: 404 PSPLALSSLQATTSLGSPTLQA 425



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 21/106 (19%)

Query: 726 SIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQ----PPAR--PPPPVLPANRAPSATAP 779
           +IP  A ++ P      +   PA R  PP   +    PPA+   P PV    RA   T P
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 780 SPVGA-------------GTAAPAPSQTPGSAPPPQAQGPPYPTYP 812
            P+G              G A  AP ++  SA   +    P P  P
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 52/163 (31%), Positives = 59/163 (36%), Gaps = 43/163 (26%)

Query: 723 SAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPV 782
           +APS+  P     P  G  P PP P P    P  P PP  PPPP  P    P+ T P P 
Sbjct: 670 AAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPP- 728

Query: 783 GAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQM--------------PMPMGYNP 828
                 PAP   PG  PPP    PP P +P  PG   +               MPM +  
Sbjct: 729 ----PLPAP---PGVPPPPIL--PPLPPFP--PGLFPVMQVDMSHVLGGQWGGMPMSFQM 777

Query: 829 YAY-------GQYNMPYPPVYHQSPGQA----------PYPGP 854
                     GQ   PYPP    +   A          PY GP
Sbjct: 778 QTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGP 820



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 18/120 (15%)

Query: 754 PTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPG 813
           P+ P   A  P P++    A +  APS +      P P   P   PPP    PP P  PG
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP----PPPPPQPG 702

Query: 814 YPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQ--PPQQSYYP 871
           +P    MP P+   P        P PP  H +    P P P  P  P P   PP   + P
Sbjct: 703 FP----MPPPLPPPP--------PPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 27/131 (20%)

Query: 712 KDLQQSIAREPSAP----SIPTPAYQSSPAGGHA------PTPPTPAPRTMPPTKPQPPA 761
           +D++ S    PSAP      P P   +  A   A      PT P P P   PP  P PP 
Sbjct: 637 EDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPP 696

Query: 762 RPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQG----PPYPTYPGYPGY 817
            PP P  P         P P+      P P+    + PPP        PP P  P  P  
Sbjct: 697 PPPQPGFPM--------PPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP-- 746

Query: 818 CQMPMPMGYNP 828
              P P G  P
Sbjct: 747 ---PFPPGLFP 754



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 78/250 (31%)

Query: 687 EILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPT 746
           E+L++ Q   + ++F R+ + D  L+     I+   S  S   P   +S  G   PTPP+
Sbjct: 504 EMLLKEQR--TKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPS 561

Query: 747 PAPRT-----MPPTK---------------PQPPARPPPP-------------------- 766
             P +     + PT                P+PP  P PP                    
Sbjct: 562 SRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDR 621

Query: 767 -----------------------VLPANRAPSATAPSPV-----GAGTAAPA------PS 792
                                   +P+    SA  P P+      A  AAP+      P 
Sbjct: 622 TPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPL 681

Query: 793 QTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYP 852
             P   PP     PP P  PG+P    +P P    P A+    +P PP+   +P   P P
Sbjct: 682 PPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPP 739

Query: 853 GPQQPSYPFP 862
               P  PFP
Sbjct: 740 PILPPLPPFP 749



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/156 (25%), Positives = 52/156 (33%), Gaps = 41/156 (26%)

Query: 716  QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTM-----PPTKPQP----------- 759
            Q+ A  P  P +P P     P     P  P  +P +M     P  +P             
Sbjct: 1450 QARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLL 1509

Query: 760  PARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQ 819
            P +P  PV P+   P         AG  AP P   P   PPP    PP P  P       
Sbjct: 1510 PGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPP----PPPPVEP------- 1558

Query: 820  MPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQ 855
                            +P+  + +Q P +A  PGP+
Sbjct: 1559 --------------TKLPFKELDNQWPSEAIPPGPR 1580



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 41/186 (22%), Positives = 56/186 (30%), Gaps = 22/186 (11%)

Query: 706  ERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP 765
            ER  +L +    +  E  A S   P        G     P P  + +    P  P R P 
Sbjct: 1202 ERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPE 1261

Query: 766  PVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTY----------PGYP 815
              L     P    P P+      P P + P   P P+     +P+           P  P
Sbjct: 1262 HDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321

Query: 816  GYCQM-----------PMPMGYNPYAYGQYNMPY-PPVYHQSPGQAPYPGPQQPSYPFPQ 863
            G C               P G  P + G   +    P    SP   P P P   S   P+
Sbjct: 1322 GLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPR 1381

Query: 864  PPQQSY 869
             P + +
Sbjct: 1382 TPGRDF 1387



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 48/178 (26%), Positives = 63/178 (35%), Gaps = 34/178 (19%)

Query: 721  EPSAPSI----PTPAYQSSPAGGHAPTP---------PTPAPRTMPPTKP---QPPARPP 764
            EPS P +    P P  +     G   +P         P P P  +P   P   +  AR P
Sbjct: 1395 EPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAP 1454

Query: 765  PPVLPANRAPSATAPSPVGAGTAAPA---PSQTPGSAP---PPQ--AQGPPYPTYPGYPG 816
             P+ P   AP A+ P P+      P    PS      P   PP   A G      PG P 
Sbjct: 1455 TPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQP- 1513

Query: 817  YCQMPM-PMGYNP------YAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQ 867
              Q P+ P  ++P      +       P PP+  Q P   P P  +    PF +   Q
Sbjct: 1514 --QTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQ 1569



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 44/174 (25%), Positives = 62/174 (35%), Gaps = 31/174 (17%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKP-------------QPPARP--PPP 766
            P  P  P P  +++ A  H   PP P     PP  P               PA P   PP
Sbjct: 1287 PPRPPSPPPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345

Query: 767  VLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPY---PTYPGYPGYCQM--- 820
            +   +   S ++P   G+  + PAPS +  S   P+  G  +   PT+    G   +   
Sbjct: 1346 LSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVC 1405

Query: 821  PMPMGYNPYAYG--------QYNMPYP-PVYHQSPGQAPYPGPQQPSYPFPQPP 865
            P+P G      G        +  +P P P+    P   P     Q   P P PP
Sbjct: 1406 PLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP 1459



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 38/138 (27%), Positives = 45/138 (32%), Gaps = 28/138 (20%)

Query: 733 QSSPAGGHAPTPP--TPAPRTMPPTKP-QPPAR--PPPPVLPANRAPSAT--------AP 779
           Q S    H P P   TPAP       P Q P    PPPP  P   A            AP
Sbjct: 373 QDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAP 432

Query: 780 SPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYP 839
           +P     A P   + PG+ P P           G P +   P P           + P  
Sbjct: 433 APPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPC----------DSPGT 482

Query: 840 PVYHQSPGQAPYPGPQQP 857
           P    SP      GP++P
Sbjct: 483 PTLESSPA-----GPEKP 495



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 36/108 (33%), Positives = 40/108 (37%), Gaps = 22/108 (20%)

Query: 707  RDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPP 766
            R+ LL   Q      PS     T       AG  AP PP      +PP  P PP  PPPP
Sbjct: 1504 RELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP------LPPQPPPPP--PPPP 1555

Query: 767  VLPA--------NRAPS-ATAPSPVGAGTAAP-----APSQTPGSAPP 800
            V P         N+ PS A  P P G           A S+ P   PP
Sbjct: 1556 VEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPP 1603



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 29/118 (24%), Positives = 40/118 (33%), Gaps = 32/118 (27%)

Query: 722 PSAPSIPTPAYQSS-----PAGGHAPTPP-------------------TPAPRTMPPTKP 757
           P A + P P ++S+         H P PP                    PAP  +PP +P
Sbjct: 383 PPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEP 442

Query: 758 ---QPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYP 812
              + P  PP P  P   +         G    +P P  +PG+  P     P  P  P
Sbjct: 443 LAKEKPGTPPGPPPPDTNSMELGGRPTFG---WSPEPCDSPGT--PTLESSPAGPEKP 495



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 43/179 (24%), Positives = 65/179 (36%), Gaps = 25/179 (13%)

Query: 700  VFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP 759
            V AR+ E +E   + ++ +A E  A + P    Q       AP  P      M     + 
Sbjct: 1138 VVAREEEEEE---EEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGME----EE 1190

Query: 760  PARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPY--PTYPGYPGY 817
                   V P  R PS     P+  G   PA S+ P   P    +G     P  P     
Sbjct: 1191 VDIETEAVAPEER-PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVE 1249

Query: 818  CQMPMPMGYNPYAYGQYNM---PYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873
             + P+    +P    ++++   P PP+          P P QP  P P+PP+    P +
Sbjct: 1250 ARPPL----SPERAPEHDLEVEPEPPMM--------LPLPLQPPLPPPRPPRPPSPPPE 1296


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 62/184 (33%), Positives = 75/184 (40%), Gaps = 39/184 (21%)

Query: 716  QSIAREPSAPSIPTP--AYQSSPAGGHA-------PTPPT---PAPRTMPPTK-----PQ 758
            + I   PS    PTP  A   SP GG A       PTPP    P+P+  P T      P 
Sbjct: 928  KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987

Query: 759  PPARPPP-----PVLPANRA----PSATAPSPVGAGTAAPAP--SQTPGSAPPPQAQGPP 807
            PPA  PP     P  P+ +     P+ T PSP G+  A P P  + TP +A PP  +G P
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047

Query: 808  YPT-----YPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPS-YPF 861
              T      P  P    +P P G  P        P PP    +   +P  GP  PS    
Sbjct: 1048 AATPLPKGAPTTPA-ATLPSPKG-GPATPSLKGAPTPPA---ATPPSPKGGPATPSPKGA 1102

Query: 862  PQPP 865
            P PP
Sbjct: 1103 PMPP 1106



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 56/157 (35%), Positives = 63/157 (40%), Gaps = 20/157 (12%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP---ARPPPPVLPANRAPSATAPS 780
            AP+ P  A   SP GG A   P  AP T   T P P    A P P   P    P+AT PS
Sbjct: 1194 APTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT--TPAATPPS 1250

Query: 781  PVGAGTAAPAP--SQTPGSAPPPQAQG----PPYPTYPGYPGYCQMPMPMGYNPYAYGQY 834
            P G G A P P  + TP +A PP  +G    PP+   P  P     P P G  P      
Sbjct: 1251 PKG-GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN-PAVVTPPSPKG-GPATSPPK 1307

Query: 835  NMPYPPVY-----HQSPGQAPYPGPQQPSYPFPQPPQ 866
              P PP         SPG  P  G   P    P  P+
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 52/160 (32%), Positives = 59/160 (36%), Gaps = 25/160 (15%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP---ARPPPPVLPANRAPSATA 778
            P    +P  A   SP GG A  P   AP T   T P P    A PPP   P    P+AT 
Sbjct: 1099 PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT--TPAATP 1156

Query: 779  PSPVGAGTAAPAPS---QTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYN 835
            PSP G G A P P     TP + PP    G   P+  G P       P    P   G   
Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP-----TTPAATPPSPKGGLA 1210

Query: 836  MPYPPVYHQSPGQAPYPGPQ----------QPSYPFPQPP 865
             P P     +P   P P P+           P+ P   PP
Sbjct: 1211 TPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPP 1249



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 50/168 (29%), Positives = 58/168 (34%), Gaps = 27/168 (16%)

Query: 722  PSAPSIPTP--AYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLP--ANRAPSAT 777
            PS    PTP  A   SP GG A   P  AP     T P P   P     P  A+  P+AT
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 778  APSPVGAGTAAPAPSQTP--------------------GSAPPPQAQGPPYPTYPGYPGY 817
             PSP G+  A P P   P                    G+  PP A  P     P  P  
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 818  CQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
               PMP    P +  +  +  PP  H+     P   P  P      PP
Sbjct: 1100 KGAPMPPAATPPS-PKGGLATPP--HKGAPTTPAATPPSPKGGLATPP 1144



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 53/155 (34%), Positives = 61/155 (39%), Gaps = 16/155 (10%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP---ARPPPPVLPANRAPSATAPS 780
            AP+ P  A   SP GG A  PP  AP T   T P P    A P P   P    P+AT PS
Sbjct: 1148 APTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT--TPAATPPS 1204

Query: 781  PVGAGTAAPAPS---QTPGSAPPPQAQGPPYPTYPGYP--GYCQMPMPMG--YNPYAYGQ 833
            P G G A P+P     TP + PP    G   P+  G P       P P G    P   G 
Sbjct: 1205 PKG-GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263

Query: 834  YNMP--YPPVYHQSPGQAPYPGPQQPSYPFPQPPQ 866
               P   PP         P+ G   P+   P  P+
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK 1298



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 52/155 (33%), Positives = 60/155 (38%), Gaps = 20/155 (12%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP----ARPPPPVLPANRAPSATAP 779
            AP+ P  A   SP GG A TPP     T P   P  P    A PPP   P    P+AT P
Sbjct: 1125 APTTPA-ATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGGLATPPPKGAPT--TPAATPP 1180

Query: 780  SPVGAGTAAPAPS---QTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNM 836
            SP G G A P+P     TP + PP    G   P+  G P       P    P   G    
Sbjct: 1181 SPKG-GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-----TTPAATPPSPKGGLAT 1234

Query: 837  PYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
            P P     +P   P   P     P   PP+ +  P
Sbjct: 1235 PSPKGAPTTPAATP---PSPKGGPATPPPKGAPTP 1266



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 56/175 (32%), Positives = 71/175 (40%), Gaps = 44/175 (25%)

Query: 722  PSAPSIP-------TPAYQSSPAGGHAPTPP-----TPAPRTMPPTKPQPPARPPPPVLP 769
            PS  ++P       TPA + +PA     + P     TPAP+ +P + P P   P PP   
Sbjct: 888  PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS-PSPKGAPTPP--- 943

Query: 770  ANRAPSATAPSPVGAGTAAPAP--SQTPGSAPPPQAQG------------PPYPTYPGYP 815
                 +AT PSP G G A P+P  + TP +A PP  +G            PP  T P   
Sbjct: 944  -----AATPPSPKG-GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 816  GYCQMPMPMGY-NPYAYGQYNMPYPPVYHQSPGQAPYP-GPQQPSYPFPQPPQQS 868
            G    P P G   P A        PP    SP   P+P G   P    P  P+ S
Sbjct: 998  GGPATPSPKGAPTPPAV------TPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 52/160 (32%), Positives = 57/160 (35%), Gaps = 23/160 (14%)

Query: 722  PSAPSIPTP--AYQSSPAGGHAPTPPTPAPRTMPPTKPQPP-ARPPPPVLPANRAPSATA 778
            PS    PTP  A   SP GG A   P  AP     T P P      PP   A   P+AT 
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 779  PSPVGAGTAAPAPS---QTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYN 835
            PSP G G A P P     TP + PP    G   P   G P       P    P   G   
Sbjct: 1134 PSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP-----TTPAATPPSPKGGLA 1187

Query: 836  MPYPPVYHQSPGQAPYPGPQ----------QPSYPFPQPP 865
             P P     +P   P P P+           P+ P   PP
Sbjct: 1188 TPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPP 1226



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 54/161 (33%), Positives = 60/161 (37%), Gaps = 24/161 (14%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP----ARPPP---PVLPANRAPS- 775
            AP+ P  A   SP GG A   P  AP T P   P  P    A P P   P  PA   PS 
Sbjct: 1171 APTTPA-ATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228

Query: 776  ---ATAPSPVGAGT----AAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGY-N 827
                  PSP GA T      P+P   P + PP  A  PP  T P   G    P   G  N
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288

Query: 828  PYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
            P       +  PP     P  +P  G   P    P  P+ S
Sbjct: 1289 P------AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 51/157 (32%), Positives = 60/157 (38%), Gaps = 38/157 (24%)

Query: 733 QSSPAGGHAPTPPT----PAPRTMPPTKPQ----PPARPPPPVL---------PANRAP- 774
           + SPA  H+PTPP+    P P  + P  P+    PP   P P +         PA  AP 
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906

Query: 775 -----SATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPY 829
                S T+ SP  A  A PAP   P S  P  A  PP  T P   G    P P      
Sbjct: 907 QAPALSMTSSSPKKA-RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW---- 961

Query: 830 AYGQYNMPYPPVYHQSPGQAPYPGPQQPS-YPFPQPP 865
                  P PP    +   +P  GP  PS    P PP
Sbjct: 962 ------APTPPA---ATPPSPKGGPATPSPKGAPTPP 989



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 44/119 (36%), Positives = 45/119 (37%), Gaps = 15/119 (12%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTP-PTPAPRTMPPTKPQP---PARP-------PPPVLPA 770
            P   S P  A   SP G  A TP P  AP T   T P P   PA P       PP   P 
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 771  NRAPSATAPSPVGA--GTAAPAPSQTPGSAPPPQAQGP--PYPTYPGYPGYCQMPMPMG 825
            +       PSP GA    AA  PS   G A PP    P  P  T P   G    P P G
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG 1147



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 47/152 (30%), Positives = 58/152 (38%), Gaps = 20/152 (13%)

Query: 722  PSAPSIPTPAYQSSPA--GGHAPTPPTPAPRTMPPTKPQPPARP---PPPVLPANRAPSA 776
            P     PTP   + P+  GG A  P   AP     T P P   P   PP   P    P+A
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT--PPAA 1315

Query: 777  TAPSPVGA-GTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYN 835
            T PSP G+ GT  P  + TP +  PP  +G   PT P        P   G  P       
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT--PTLP-----ATTPSSKG-GPTTPSSKE 1367

Query: 836  MPYPPV----YHQSPGQAPYPGPQQPSYPFPQ 863
             P PP     +   P   P    + P+ P P+
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 50/159 (31%), Positives = 65/159 (40%), Gaps = 20/159 (12%)

Query: 722  PSAPSIPTPAYQS--SPAGGHAPTPPTPAPRTMP-PTKPQPPARPPPPVLPANRAPSAT- 777
            PS    PTP+  +  SP G   P   TP P  +  P   + PA P P   PA    S++ 
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 778  -----APSPVGAGTAAPAP--SQTPGSAPPPQAQG---PPYPTYPGYPGYCQMPMPMGYN 827
                  P+P G   A+P+P  + TP +A PP  +G    P P +   P     P P G  
Sbjct: 919  KKARATPAPKGI-PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG-G 976

Query: 828  PYAYGQYNMPYPPVYHQSPGQAPYPGPQQPS-YPFPQPP 865
            P        P PP    +   +P  GP  PS    P PP
Sbjct: 977  PATPSPKGAPTPPA---ATPPSPKGGPATPSPKGAPTPP 1012



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 34/94 (36%), Positives = 41/94 (43%), Gaps = 7/94 (7%)

Query: 725  PSIPTPAYQ-SSPAGGHAPTPPTPAPRTM-----PPTKPQPPARPPPPVLPANRAPSATA 778
            P+IPTP    ++P+   A +PP   P T      P     PPA   P    A   P+ T 
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621

Query: 779  PSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYP 812
            PSP   G A PAP  TP S P   +     PT P
Sbjct: 1622 PSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 3/97 (3%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPP-PPVLPANRAPSATAPS 780
            P     P  A   SP G     PP  AP     T P P   P  P   P+++    T  S
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 781  PVGAGTAAPAPSQTPGSA--PPPQAQGPPYPTYPGYP 815
              G    A  PS   G A  PP   +GP  P+  G P
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPP--TPAPRTMPPTKPQPPARP-PPPVLPANRAPSATA 778
            PS   +  P   +SP+   APTPP  TP      P  P P   P  PPV P++   S T+
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653

Query: 779  PSPVGAGTAAPAPSQTPGSAPPPQAQGP 806
            P+ V     A  P  + G    P  +GP
Sbjct: 1654 PASVTCKMGATVPQASKGL---PAKKGP 1678



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 51/161 (31%), Positives = 59/161 (36%), Gaps = 32/161 (19%)

Query: 724  APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP-----PARPPPPVLPANRAPSATA 778
            AP+ P  A   SP GG  P  P+      PP    P     PA P P   P    P+AT 
Sbjct: 1056 APTTPA-ATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPSPKGAP--MPPAATP 1110

Query: 779  PSPVGAGTAAP----APSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQY 834
            PSP G G A P    AP+ TP + PP    G   P   G P       P    P   G  
Sbjct: 1111 PSPKG-GLATPPHKGAPT-TPAATPPSPKGGLATPPPKGAP-----TTPAATPPSPKGGL 1163

Query: 835  NMPYPPVYHQSPGQAPYPGPQ----------QPSYPFPQPP 865
              P P     +P   P P P+           P+ P   PP
Sbjct: 1164 ATPPPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPP 1203



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/161 (26%), Positives = 56/161 (34%), Gaps = 19/161 (11%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPP--TPAPRTMPPTKPQPPARPPPPVLPANRA-PSATA 778
            P     PTP   + P+    PT P  TP+ +  P T        PP   P+++  P+ T 
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386

Query: 779  PSPVGAGTAAPAPSQTPGS------------APPPQAQGPPYPTYPGYPGYCQMPMPMGY 826
            PSP   G A P+P   P S            A P   +G   P+          P+ +  
Sbjct: 1387 PSPK-RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 827  NPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQ 867
             P        P  P    S G    P    PS   P  P+Q
Sbjct: 1446 APATSAPKGGPATP---SSKGDPTLPAVTPPSPKEPPAPKQ 1483



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/105 (29%), Positives = 39/105 (37%), Gaps = 28/105 (26%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA-------- 773
            P A ++P+P            TP  P P+  P T     A  PP V P+           
Sbjct: 1550 PPAMTVPSPK----------KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 774  ---PSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYP 815
               P+ T+PSP      AP P   P   PP   +GP  P   G P
Sbjct: 1600 LIPPAVTSPSP----KEAPTP---PAVTPPSPEKGPATPAPKGTP 1637



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 27/170 (15%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPA--NRAPSATAP 779
            PS+   PT    + P+    P P   A  + P   P  PA    P LPA    +P     
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518

Query: 780  SPVG-----AGTAAPAPSQTPGSAPPPQAQGPPYPTY---------------PGYPGYCQ 819
            +P       A TA     +TP +  P +A  PP  T                P  P   +
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578

Query: 820  MPMPMGYNPYAYGQYNMPY-----PPVYHQSPGQAPYPGPQQPSYPFPQP 864
               P    P  Y     P      P V   SP +AP P    P  P   P
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 6/82 (7%)

Query: 734  SSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATA---PSPVGAGTAAPA 790
            S+P GG A TP +    T+P   P  P  PP P   A  +    A   P+P+GA T    
Sbjct: 1450 SAPKGGPA-TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508

Query: 791  PSQTPGSAP--PPQAQGPPYPT 810
               +P   P  P   + P  PT
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPT 1530



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 11/105 (10%)

Query: 745 PTPAPRTMPPTK---PQPPARPPPPVLPANRAPSATA----PSPVGAGTAAPAPSQTPGS 797
           P  A  T+P T+   PQP A     VLP + A S TA    P P      +PAP Q P S
Sbjct: 2   PGEATETVPATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLS 59

Query: 798 APPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVY 842
           A    +  P   T    P   ++P P   +  A      P  P +
Sbjct: 60  AANQASPFPSPSTIASTP--LEVPFPQSSSGTALPLGTAPEAPTF 102



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 35/146 (23%), Positives = 48/146 (32%), Gaps = 19/146 (13%)

Query: 730  PAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP-SATAPSPVGAGTAA 788
            PA +S+P       P    P+T   +   PP  P P     ++ P S  AP+P+      
Sbjct: 1688 PAPESTPI---ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL-----L 1739

Query: 789  PAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQ 848
            P    +  +A    A   P        G    P      P     +    P     S   
Sbjct: 1740 PVQKDSSKTAKGKDASHSP-------KGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 849  APYPGPQQPSYPFP---QPPQQSYYP 871
            AP P    P  P P    PP+Q + P
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLP 1818



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 717 SIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTM-PPTKPQPPARPPPPVLPANR-AP 774
           +IA  P     P  +  ++   G AP  PT  P  + PP  P   A   P + P  +  P
Sbjct: 72  TIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTP 131

Query: 775 SATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPP 807
           S++AP  + A   AP   Q   + PP     PP
Sbjct: 132 SSSAPLALVA--LAPHSVQKSSAFPPNLLTSPP 162



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 34/136 (25%), Positives = 48/136 (35%), Gaps = 13/136 (9%)

Query: 722  PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSP 781
            PS+P    PA  SS     APT    + +T     P+    PP   +P+ +   A     
Sbjct: 1510 PSSPK-EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568

Query: 782  VGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP- 840
                T +   + +P +  P   +G P P     P     P P             P PP 
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK----------EAPTPPA 1618

Query: 841  VYHQSPGQAP-YPGPQ 855
            V   SP + P  P P+
Sbjct: 1619 VTPPSPEKGPATPAPK 1634



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 33/132 (25%), Positives = 49/132 (37%), Gaps = 20/132 (15%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSP 781
           P+ P   +PA Q  P        P P+P T+  T  + P             P +++ + 
Sbjct: 43  PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP------------FPQSSSGTA 90

Query: 782 VGAGTAAPAPSQTPGSAPPP-----QAQGPPY--PTYPGYPGYCQMPMPMGYNPYAYGQY 834
           +  GTA  AP+  P    PP      A   P   PT  G P        +   P++  Q 
Sbjct: 91  LPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSV-QK 149

Query: 835 NMPYPPVYHQSP 846
           +  +PP    SP
Sbjct: 150 SSAFPPNLLTSP 161


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 53/170 (31%), Positives = 62/170 (36%), Gaps = 23/170 (13%)

Query: 722  PSAPSIP------TPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPS 775
            PSA S P      TP  Q  PA    P  P P     PPT+P PP RPPPP   +  +P 
Sbjct: 1074 PSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ 1133

Query: 776  A--TAPSPVGAGTAAPAPSQTPGSAPPPQAQG----------PPYPTYPGYPGYCQMPMP 823
            A    P P G  TA P      G    PQ+                T     G   +P P
Sbjct: 1134 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1193

Query: 824  MGYNPYAYGQYNMPYPPVYHQSP-----GQAPYPGPQQPSYPFPQPPQQS 868
            +        Q ++P P    Q P        P  GPQ      PQPP +S
Sbjct: 1194 LKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS 1243



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 44/142 (30%), Positives = 57/142 (40%), Gaps = 18/142 (12%)

Query: 727  IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP--PVLPANRAPSAT------A 778
            +P     SS +G    T P+ +PRT P   P     P P  P+ P +RAPS T       
Sbjct: 1021 LPQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQ 1077

Query: 779  PSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPY 838
             SP+ A  A P P + P     P+   PP P  P        P P    P   G+ + P 
Sbjct: 1078 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP-----TRPAPPQRPPPPSGR-SQPS 1131

Query: 839  PPVYHQSPGQAPYPGPQQPSYP 860
            P      PG A Y    +P+ P
Sbjct: 1132 PQAGLAGPGPAGY-STARPTIP 1152



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 5/66 (7%)

Query: 721  EPSAPSIPTPAYQS-SPAGGHAPTPPTPAPRTMPPTKPQP----PARPPPPVLPANRAPS 775
            EP  P    P   S  P       P  P    MP + PQP    P +PPP    ++  PS
Sbjct: 1192 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPS 1251

Query: 776  ATAPSP 781
              +  P
Sbjct: 1252 EASSQP 1257


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 51/164 (31%), Positives = 63/164 (38%), Gaps = 9/164 (5%)

Query: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPT----PPTPAPRTMPPTKPQPPARPPPPVLPA 770
           QQ   + P+    PT      P  G  P     P   + +   PTKP  P++ P P  P 
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP--PSQLPGPAKPP 480

Query: 771 NRAPSATAPSPVGAGTAAPAPSQTPGSA-PPPQAQGPPYPTYPGYPGYCQMPMPMGYNPY 829
            + P    P P   G+A P PSQ PGS  PPPQ  GP  P+ P  PG  + P     +  
Sbjct: 481 PQQPGPAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAK 538

Query: 830 AYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873
              Q   P  P   QS       G  +P  P    P     P Q
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 50/160 (31%), Positives = 61/160 (38%), Gaps = 26/160 (16%)

Query: 716 QSIAREPSAPSIPT--------PAYQSSPAGGHAP-TPPTPAPRTMP-PTKPQP----PA 761
           QS A+ P     P         PA Q+ P    A  T PT  P  +P P KP P    PA
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 762 RPPPP----VLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPT----YPG 813
           +PPP       P ++ P +T P P   G A P+P Q   + PP Q  G   P+     P 
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547

Query: 814 YPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPG 853
            P   Q   P+       G      PP    S  Q P  G
Sbjct: 548 KPSAQQSTKPVSQT----GSGKPLQPPTVSPSAKQPPSQG 583



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 68/228 (29%), Positives = 79/228 (34%), Gaps = 65/228 (28%)

Query: 691 RFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSI--PTPAYQSSPAGGHAPTPPTPA 748
           R Q K +DIV      R E +K    S    PS P I  PTP    +   GH  + P PA
Sbjct: 280 RPQTKQADIV------RGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329

Query: 749 ---------------------PRTMPPTKPQPPARP-----PPPVLPANRAPSATAPSPV 782
                                P   PP   +PPA+P     PP     +  PS+  P P 
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389

Query: 783 GAGT---AAPAPSQTPGSAPPPQAQ-GPPYP--TYPGYPGYCQMPMP------------- 823
                      P+Q PG A PP  Q G P P    PG     + P P             
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 824 ----MGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQ 867
                G    +  Q     PP   Q PG A  P PQQP  P   PPQQ
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPP--SQLPGPAK-PPPQQPG-PAKPPPQQ 493



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 51/164 (31%), Positives = 60/164 (36%), Gaps = 16/164 (9%)

Query: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP 774
           QQ    +P    + TP   +   G  +P    P P   P  +P P   P     P   + 
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 775 SATAPSPVGAGTAAPA--PSQTPGSA-PPPQAQGPPYPTYPGYPGYC----QMPMPMGYN 827
             T P+   +    PA  P Q PG A PPPQ  G   P     PG      Q P P   +
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP-SQQPGSTKPPPQQPGPAKPS 520

Query: 828 PYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
           P   G    P      Q PG A  P  QQPS P     QQS  P
Sbjct: 521 PQQPGSTKPP-----SQQPGSAK-PSAQQPS-PAKPSAQQSTKP 557



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 723  SAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPV 782
            S P+ P P ++SS     A  PP P P   PP  P P   PPPP LP   +P  T     
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPP---PPPPPLPPPTSPKPTILPKK 2441

Query: 783  GAGTAAPAPSQTP 795
                A+P  + TP
Sbjct: 2442 KLTVASPVTTATP 2454



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 54/217 (24%), Positives = 82/217 (37%), Gaps = 23/217 (10%)

Query: 667 NFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELL-------KDLQQSIA 719
           N  EL+ ++ E   F N  TE      + C        TE  E L       + L   +A
Sbjct: 593 NTTELLLHVPEKANF-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 720 REPSAPSIP---TPAYQSSPAGGHAPTPPTPAPRT-----MPPTKPQPPARPPPPVL--P 769
             PS+P       P   +S     +P P   +P+         +K   P +PPP V    
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 770 ANRAPSATAPSPVGAGT-AAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNP 828
            + +PSA A  P  A + + PAP + P S P  Q + P     P  P   +    +  + 
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEP-SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 829 YAYGQYNMPYPPVYHQSPGQAPYP---GPQQPSYPFP 862
            A  + ++P   V  Q+  +   P      +PS  FP
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 12/90 (13%)

Query: 725 PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP-PARPPPPVLPANRAPSATAP-SPV 782
           P  P PA + SP    +  PP+  P +  P+  QP PA+P         A  +T P S  
Sbjct: 511 PQQPGPA-KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP--------SAQQSTKPVSQT 561

Query: 783 GAGTAAPAPSQTPGSAPPPQAQGPPYPTYP 812
           G+G     P+ +P +  PP +QG P    P
Sbjct: 562 GSGKPLQPPTVSPSAKQPP-SQGLPKTICP 590



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 58/269 (21%), Positives = 89/269 (33%), Gaps = 71/269 (26%)

Query: 644 MKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR 703
           +K+S +  +L+EE   ++   + + V  ++ +      +N              D++   
Sbjct: 135 LKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF------------DLISDS 182

Query: 704 KTERDELLKDLQQSIAREPSAPS--IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 761
           +  ++E  K  Q+ + +E   P   I  P  Q          PP P P+   P +  P  
Sbjct: 183 EASQEETTKK-QKVVQKEQGKPEGIIKPPLQQQ---------PPKPIPKQQGPGR-DPLQ 231

Query: 762 RPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTP-------------------------- 795
           +   P   +++ P      P G G     P+QTP                          
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291

Query: 796 ---------GSAPPPQ--AQGPPYPTYPGY----PGYCQMP-MPMGYNPYAYGQYNMPYP 839
                     S PP Q    G P    PG+    PG  + P  P G       Q     P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351

Query: 840 PVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
           PV  Q PG      P QP  P   P QQ+
Sbjct: 352 PV--QPPGTT--KPPAQPLGPAKPPAQQT 376



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 29/83 (34%), Positives = 33/83 (39%), Gaps = 15/83 (18%)

Query: 728  PTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP-----ARPPP----PVLPANRAPSATA 778
            P P  QS P    AP    PAP + PPT   PP     A P P    PV    +AP+A  
Sbjct: 952  PGPHSQSGPG---APMKQAPAP-SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007

Query: 779  PSPVGAGTAAPAPSQTPGSAPPP 801
              P      AP   +T     PP
Sbjct: 1008 LEP--KAEQAPTVKRTETEKKPP 1028



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 38/130 (29%), Positives = 44/130 (33%), Gaps = 51/130 (39%)

Query: 728 PTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP---------------------P 766
           P P  +  P G  +PTPP P P T   T P P   P P                     P
Sbjct: 864 PKPDAKPMPKG--SPTPPGPRP-TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920

Query: 767 VLP-------------------ANRAPSATAPSP---VGAGTA---APAPSQTPGSAPPP 801
             P                   +N   +A  P P    G G     APAPSQ P S  PP
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP 980

Query: 802 QA--QGPPYP 809
           ++  Q PP P
Sbjct: 981 KSTGQAPPAP 990



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 37/165 (22%), Positives = 50/165 (30%), Gaps = 24/165 (14%)

Query: 726 SIPTPAYQSSPAGGHAPTPPT-------PAPRTMPPTKPQPPARPPPPVLPANR-APSAT 777
           +IP PA  S       P+  +       P  +   P K Q    P P   P  + +P+  
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 778 APSPVGAGTAAPAPSQTPGSAPPPQAQGPPY-----------PTYPGYPGYCQMPMPMGY 826
            P P  AG   P P Q    +P PQ Q   +            + P  P         G+
Sbjct: 880 GPRPT-AGQTVPTPQQ----SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGF 934

Query: 827 NPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
               + Q +          P     PG      P P  P  S  P
Sbjct: 935 GASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 716  QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPS 775
            ++  +E  A  +P+     SP+    P  P P  R+        P  PPPP  P    P 
Sbjct: 2365 ETFGQEKPASQLPS----GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420

Query: 776  ATAPSPVGAGTAAPAPSQTP 795
               P P+   T +P P+  P
Sbjct: 2421 PPPPPPLPPPT-SPKPTILP 2439



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 18/57 (31%), Positives = 20/57 (35%), Gaps = 1/57 (1%)

Query: 754  PTKPQPPARPPPPVLPANRAPSATAPS-PVGAGTAAPAPSQTPGSAPPPQAQGPPYP 809
            P    P   P    LPA   P   + S  + A    P P   P   PPP    PP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 51/164 (31%), Positives = 63/164 (38%), Gaps = 9/164 (5%)

Query: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPT----PPTPAPRTMPPTKPQPPARPPPPVLPA 770
           QQ   + P+    PT      P  G  P     P   + +   PTKP  P++ P P  P 
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP--PSQLPGPAKPP 480

Query: 771 NRAPSATAPSPVGAGTAAPAPSQTPGSA-PPPQAQGPPYPTYPGYPGYCQMPMPMGYNPY 829
            + P    P P   G+A P PSQ PGS  PPPQ  GP  P+ P  PG  + P     +  
Sbjct: 481 PQQPGPAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAK 538

Query: 830 AYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 873
              Q   P  P   QS       G  +P  P    P     P Q
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 50/160 (31%), Positives = 61/160 (38%), Gaps = 26/160 (16%)

Query: 716 QSIAREPSAPSIPT--------PAYQSSPAGGHAP-TPPTPAPRTMP-PTKPQP----PA 761
           QS A+ P     P         PA Q+ P    A  T PT  P  +P P KP P    PA
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 762 RPPPP----VLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPT----YPG 813
           +PPP       P ++ P +T P P   G A P+P Q   + PP Q  G   P+     P 
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547

Query: 814 YPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPG 853
            P   Q   P+       G      PP    S  Q P  G
Sbjct: 548 KPSAQQSTKPVSQT----GSGKPLQPPTVSPSAKQPPSQG 583



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 68/228 (29%), Positives = 79/228 (34%), Gaps = 65/228 (28%)

Query: 691 RFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSI--PTPAYQSSPAGGHAPTPPTPA 748
           R Q K +DIV      R E +K    S    PS P I  PTP    +   GH  + P PA
Sbjct: 280 RPQTKQADIV------RGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329

Query: 749 ---------------------PRTMPPTKPQPPARP-----PPPVLPANRAPSATAPSPV 782
                                P   PP   +PPA+P     PP     +  PS+  P P 
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389

Query: 783 GAGT---AAPAPSQTPGSAPPPQAQ-GPPYP--TYPGYPGYCQMPMP------------- 823
                      P+Q PG A PP  Q G P P    PG     + P P             
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 824 ----MGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQ 867
                G    +  Q     PP   Q PG A  P PQQP  P   PPQQ
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPP--SQLPGPAK-PPPQQPG-PAKPPPQQ 493



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 51/164 (31%), Positives = 60/164 (36%), Gaps = 16/164 (9%)

Query: 715 QQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP 774
           QQ    +P    + TP   +   G  +P    P P   P  +P P   P     P   + 
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 775 SATAPSPVGAGTAAPA--PSQTPGSA-PPPQAQGPPYPTYPGYPGYC----QMPMPMGYN 827
             T P+   +    PA  P Q PG A PPPQ  G   P     PG      Q P P   +
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP-SQQPGSTKPPPQQPGPAKPS 520

Query: 828 PYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
           P   G    P      Q PG A  P  QQPS P     QQS  P
Sbjct: 521 PQQPGSTKPP-----SQQPGSAK-PSAQQPS-PAKPSAQQSTKP 557



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 723  SAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPV 782
            S P+ P P ++SS     A  PP P P   PP  P P   PPPP LP   +P  T     
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPP---PPPPPLPPPTSPKPTILPKK 2441

Query: 783  GAGTAAPAPSQTP 795
                A+P  + TP
Sbjct: 2442 KLTVASPVTTATP 2454



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 54/217 (24%), Positives = 82/217 (37%), Gaps = 23/217 (10%)

Query: 667 NFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELL-------KDLQQSIA 719
           N  EL+ ++ E   F N  TE      + C        TE  E L       + L   +A
Sbjct: 593 NTTELLLHVPEKANF-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 720 REPSAPSIP---TPAYQSSPAGGHAPTPPTPAPRT-----MPPTKPQPPARPPPPVL--P 769
             PS+P       P   +S     +P P   +P+         +K   P +PPP V    
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 770 ANRAPSATAPSPVGAGT-AAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNP 828
            + +PSA A  P  A + + PAP + P S P  Q + P     P  P   +    +  + 
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEP-SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 829 YAYGQYNMPYPPVYHQSPGQAPYP---GPQQPSYPFP 862
            A  + ++P   V  Q+  +   P      +PS  FP
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 12/90 (13%)

Query: 725 PSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQP-PARPPPPVLPANRAPSATAP-SPV 782
           P  P PA + SP    +  PP+  P +  P+  QP PA+P         A  +T P S  
Sbjct: 511 PQQPGPA-KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP--------SAQQSTKPVSQT 561

Query: 783 GAGTAAPAPSQTPGSAPPPQAQGPPYPTYP 812
           G+G     P+ +P +  PP +QG P    P
Sbjct: 562 GSGKPLQPPTVSPSAKQPP-SQGLPKTICP 590



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 58/269 (21%), Positives = 89/269 (33%), Gaps = 71/269 (26%)

Query: 644 MKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR 703
           +K+S +  +L+EE   ++   + + V  ++ +      +N              D++   
Sbjct: 135 LKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF------------DLISDS 182

Query: 704 KTERDELLKDLQQSIAREPSAPS--IPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPA 761
           +  ++E  K  Q+ + +E   P   I  P  Q          PP P P+   P +  P  
Sbjct: 183 EASQEETTKK-QKVVQKEQGKPEGIIKPPLQQQ---------PPKPIPKQQGPGR-DPLQ 231

Query: 762 RPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTP-------------------------- 795
           +   P   +++ P      P G G     P+QTP                          
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291

Query: 796 ---------GSAPPPQ--AQGPPYPTYPGY----PGYCQMP-MPMGYNPYAYGQYNMPYP 839
                     S PP Q    G P    PG+    PG  + P  P G       Q     P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351

Query: 840 PVYHQSPGQAPYPGPQQPSYPFPQPPQQS 868
           PV  Q PG      P QP  P   P QQ+
Sbjct: 352 PV--QPPGTT--KPPAQPLGPAKPPAQQT 376



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 29/83 (34%), Positives = 33/83 (39%), Gaps = 15/83 (18%)

Query: 728  PTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPP-----ARPPP----PVLPANRAPSATA 778
            P P  QS P    AP    PAP + PPT   PP     A P P    PV    +AP+A  
Sbjct: 952  PGPHSQSGPG---APMKQAPAP-SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007

Query: 779  PSPVGAGTAAPAPSQTPGSAPPP 801
              P      AP   +T     PP
Sbjct: 1008 LEP--KAEQAPTVKRTETEKKPP 1028



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 38/130 (29%), Positives = 44/130 (33%), Gaps = 51/130 (39%)

Query: 728 PTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPP---------------------P 766
           P P  +  P G  +PTPP P P T   T P P   P P                     P
Sbjct: 864 PKPDAKPMPKG--SPTPPGPRP-TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920

Query: 767 VLP-------------------ANRAPSATAPSP---VGAGTA---APAPSQTPGSAPPP 801
             P                   +N   +A  P P    G G     APAPSQ P S  PP
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP 980

Query: 802 QA--QGPPYP 809
           ++  Q PP P
Sbjct: 981 KSTGQAPPAP 990



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 37/165 (22%), Positives = 50/165 (30%), Gaps = 24/165 (14%)

Query: 726 SIPTPAYQSSPAGGHAPTPPT-------PAPRTMPPTKPQPPARPPPPVLPANR-APSAT 777
           +IP PA  S       P+  +       P  +   P K Q    P P   P  + +P+  
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 778 APSPVGAGTAAPAPSQTPGSAPPPQAQGPPY-----------PTYPGYPGYCQMPMPMGY 826
            P P  AG   P P Q    +P PQ Q   +            + P  P         G+
Sbjct: 880 GPRPT-AGQTVPTPQQ----SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGF 934

Query: 827 NPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
               + Q +          P     PG      P P  P  S  P
Sbjct: 935 GASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 716  QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPS 775
            ++  +E  A  +P+     SP+    P  P P  R+        P  PPPP  P    P 
Sbjct: 2365 ETFGQEKPASQLPS----GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420

Query: 776  ATAPSPVGAGTAAPAPSQTP 795
               P P+   T +P P+  P
Sbjct: 2421 PPPPPPLPPPT-SPKPTILP 2439



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 18/57 (31%), Positives = 20/57 (35%), Gaps = 1/57 (1%)

Query: 754  PTKPQPPARPPPPVLPANRAPSATAPS-PVGAGTAAPAPSQTPGSAPPPQAQGPPYP 809
            P    P   P    LPA   P   + S  + A    P P   P   PPP    PP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 37/96 (38%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 716 QSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRA-- 773
           Q  A  P   SIP P    S  G  +P PP P     PP  P PP  PPPP+ P + A  
Sbjct: 641 QQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP--PPPPLPPPSSAGP 698

Query: 774 PSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYP 809
           P    P P+    A P P   P + PPP    PP P
Sbjct: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPP 734



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 54/177 (30%), Positives = 63/177 (35%), Gaps = 33/177 (18%)

Query: 692 FQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIP-----TPAYQSSPAGGH-----A 741
           F+N C       +T+R+  LK  +       S   +P     +   Q SP   H     A
Sbjct: 577 FRNVCV------QTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAA 630

Query: 742 PTPPTPAPRTMPPTKPQPPAR-PPPPVLPANRAPSATAPS--PVGAGTAAPAPSQTPGSA 798
             P            P PPA  PPPP LP+     + AP   PV AG   P P   P   
Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690

Query: 799 PPPQ-AQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP 854
           PPP  A  PP P  P  P     P P G             PP     PG AP P P
Sbjct: 691 PPPSSAGPPPPPPPPPLPNSPAPPNPGG-------------PPPAPPPPGLAPPPPP 734



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 27/94 (28%), Positives = 31/94 (32%), Gaps = 4/94 (4%)

Query: 718 IAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSAT 777
           ++  P  P  P P     P     P PP P P    P  P PP    PP  PA   P   
Sbjct: 674 VSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPL--PNSPAPPNPGGPP--PAPPPPGLA 729

Query: 778 APSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTY 811
            P P G      + S      P  +   P  P Y
Sbjct: 730 PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLY 763


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 57/155 (36%), Positives = 67/155 (43%), Gaps = 38/155 (24%)

Query: 701 FARKTERDELLKDLQQSIAREPSAPSI------PTPAYQSSPA-----GGHAPTPP---- 745
           F  KT   E +K+  +  A  P  PS       P P + S P      G  AP PP    
Sbjct: 258 FIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA 317

Query: 746 -TPAPRTMPPTKPQ------PPAR---PPPPVLPANRAPSATAPSP---VGAGTAAPAPS 792
            T AP   PP++P       PP R   PPPP LP++ APS   P P   +G G  AP P 
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS-APSGPPPPPPSVLGVGPVAPPP- 375

Query: 793 QTPGSAPPPQAQGPPYPTYPGYP--GYCQMPMPMG 825
                 PPP   GPP P  PG P  G  Q+P   G
Sbjct: 376 ----PPPPPPPPGPPPP--PGLPSDGDHQVPTTAG 404



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 43/125 (34%), Positives = 47/125 (37%), Gaps = 12/125 (9%)

Query: 741 APTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPP 800
           AP PP P+ R  PP  P PP    PP  PA            G G   P PS+ P +APP
Sbjct: 276 APPPPPPS-RGGPPPPPPPPHNSGPPPPPAR-----------GRGAPPPPPSRAPTAAPP 323

Query: 801 PQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYP 860
           P     P    P  P     P P    P +      P PP        AP P P  P  P
Sbjct: 324 PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP 383

Query: 861 FPQPP 865
            P PP
Sbjct: 384 GPPPP 388



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 7/73 (9%)

Query: 799 PPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPS 858
           PPP ++G P P  P  P +   P P    P A G+   P PP         P P P +PS
Sbjct: 279 PPPPSRGGPPPPPP--PPHNSGPPP----PPARGR-GAPPPPPSRAPTAAPPPPPPSRPS 331

Query: 859 YPFPQPPQQSYYP 871
              P PP    YP
Sbjct: 332 VAVPPPPPNRMYP 344



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 9/79 (11%)

Query: 717 SIAREPSAPSI----PTPAYQSSPAGGHAPTPPTP---APRTMPPTKPQPPARPPPPVLP 769
           S+A  P  P+     P PA  SS   G  P PP+     P   PP  P PP  PP P  P
Sbjct: 331 SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP--PPPPPPPPGPPPP 388

Query: 770 ANRAPSATAPSPVGAGTAA 788
                      P  AG  A
Sbjct: 389 PGLPSDGDHQVPTTAGNKA 407


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 47/141 (33%), Positives = 60/141 (42%), Gaps = 30/141 (21%)

Query: 724 APSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVG 783
           +PS P PA    P G    +PP P P   PP  P PP   PPP++          P PVG
Sbjct: 296 SPSHPPPA---PPLG----SPPGPKPGFAPPPAPPPP---PPPMIGI-----PPPPPPVG 340

Query: 784 AGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYH 843
            G        +PG+ PPP       P++P +P +   P P    P A     +P PP+  
Sbjct: 341 FG--------SPGTPPPPSP-----PSFPPHPDFAAPPPPP--PPPAADYPTLPPPPLSQ 385

Query: 844 QSPGQAPYPGPQQPSYPFPQP 864
            + G  P P P  P  P P P
Sbjct: 386 PTGGAPPPPPPPPPPGPPPPP 406



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 35/105 (33%), Positives = 40/105 (38%), Gaps = 11/105 (10%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKP--QPPARPPPPVLPANRAPSATAP 779
           P  P I  P        G   TPP P+P + PP      PP  PPPP       P     
Sbjct: 325 PPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLS 384

Query: 780 SPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPM 824
            P G    AP P       PPP   GPP P + G  G   +P P+
Sbjct: 385 QPTG---GAPPP------PPPPPPPGPPPPPFTGADGQPAIPPPL 420



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 53/168 (31%), Positives = 60/168 (35%), Gaps = 31/168 (18%)

Query: 724 APSIPTPAYQSSPAGGHAPT------PPTPAPRTMPPTKPQP-----PARP-------PP 765
           A S P P  QS  A   +P+      PP PA  + P    +      P R        PP
Sbjct: 243 ASSYPPPP-QSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301

Query: 766 PVLPANRAPSATAPSPVGAGTAAPAPSQTP--GSAPPPQAQG------PPYPTYPGYPGY 817
           P  P    P    P P  A   AP P   P  G  PPP   G      PP P+ P +P +
Sbjct: 302 PAPPLGSPPG---PKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH 358

Query: 818 CQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPP 865
                P    P     Y    PP   Q  G AP P P  P  P P PP
Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAP-PPPPPPPPPGPPPP 405


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 50/150 (33%), Positives = 61/150 (40%), Gaps = 12/150 (8%)

Query: 719 AREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVL--PANRAPSA 776
           A  P+ PS+PT    S+P    A     P P + PP+ P P + P P  L  P +  P A
Sbjct: 257 ALAPAPPSVPTLISDSNPLSVSASVL-VPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLA 315

Query: 777 T--APSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQY 834
              AP P  A T   AP  TP  AP P +  P  P  P  P    MP P    P +    
Sbjct: 316 LIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP----MPTP---TPSSGPPS 368

Query: 835 NMPYPPVYHQSPGQAPYPGPQQPSYPFPQP 864
                P +  +P  AP P P     P P P
Sbjct: 369 TPTLIPAFAPTPVPAPTPAPIFTPAPTPMP 398



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 45/154 (29%), Positives = 57/154 (37%), Gaps = 28/154 (18%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTPP---TPAPRTMPPTKPQPPARPPPPVLPANRAPS--- 775
           P    I  P   S+P    AP P     P P + PP  P PP+ P P   P++  PS   
Sbjct: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPT 371

Query: 776 ---ATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPT--------------YPGYPGYC 818
              A AP+PV A T  PAP  TP   P P A     PT              +P      
Sbjct: 372 LIPAFAPTPVPAPT--PAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPA 429

Query: 819 QMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYP 852
              +P+ + P   G    P  P+ +  P     P
Sbjct: 430 MQKVPLSFQP---GTVLTPSQPLVYIPPPSCGQP 460



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 47/160 (29%), Positives = 54/160 (33%), Gaps = 20/160 (12%)

Query: 722 PSAPSIPTPAYQSSPAGGHAPTP-----PTPAPRTMPPTKPQPPARPPPPVLPANRAPSA 776
           P A  +P       P  G  P       P P+    PP  P P   P PP +P     S 
Sbjct: 218 PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS----PPLAPVPALAPAPPSVPT--LISD 271

Query: 777 TAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYP----GYCQMPMPMGYNPYAYG 832
           + P  V A    P P+  P S P P +   P P             Q P+P    P A  
Sbjct: 272 SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP----PSAPT 327

Query: 833 QYNMPYP-PVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYP 871
               P P PV    P   P   P  PS P P P   S  P
Sbjct: 328 LVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPP 367



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 33/122 (27%), Positives = 39/122 (31%), Gaps = 5/122 (4%)

Query: 747 PAPRTMP--PTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQ 804
           P   T+P   T   P   P  P  P + +   + P       + PAP    G  P   A 
Sbjct: 184 PVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVAT 243

Query: 805 GPPYPTYPGYPGYCQMPMPMGYNPYAYGQYN--MPYPPVYHQSPGQAPYPGPQQPSYPFP 862
             P P+ P  P     P P    P      N       V    P  AP  GP   S P P
Sbjct: 244 SVPAPSPPLAPVPALAPAPPSV-PTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAP 302

Query: 863 QP 864
            P
Sbjct: 303 AP 304



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 20/90 (22%), Positives = 34/90 (37%), Gaps = 2/90 (2%)

Query: 717 SIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSA 776
           S   +P+   +P P   +S     A   PTP P    P+    P  P P  +P+      
Sbjct: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP--PHPAKMPSGTEQQT 591

Query: 777 TAPSPVGAGTAAPAPSQTPGSAPPPQAQGP 806
              S   +   +P   +   ++PP  ++ P
Sbjct: 592 EGTSVTFSPLKSPPQLEREMASPPECSEMP 621


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,732,062
Number of Sequences: 37866
Number of extensions: 2288432
Number of successful extensions: 52904
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 933
Number of HSP's successfully gapped in prelim test: 2054
Number of HSP's that attempted gapping in prelim test: 15500
Number of HSP's gapped (non-prelim): 17702
length of query: 873
length of database: 18,247,518
effective HSP length: 111
effective length of query: 762
effective length of database: 14,044,392
effective search space: 10701826704
effective search space used: 10701826704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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