Guide to the Human Genome
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Search of human proteins with 239749194

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo
sapiens]
         (221 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]           451   e-127
gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo ...   451   e-127
gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo ...   451   e-127
gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]           451   e-127
gi|122937323 transmembrane protein 202 [Homo sapiens]                  43   2e-04
gi|62000698 transmembrane protein 225 [Homo sapiens]                   42   3e-04
gi|188528658 transmembrane protein 182 [Homo sapiens]                  33   0.25 
gi|14211851 G protein-coupled receptor 81 [Homo sapiens]               32   0.33 
gi|116812579 transmembrane BAX inhibitor motif containing 4 [Hom...    31   0.96 
gi|28144908 clarin 1 isoform a [Homo sapiens]                          30   2.1  
gi|16506281 clarin 1 isoform c [Homo sapiens]                          30   2.1  
gi|46877066 plasticity related gene 3 [Homo sapiens]                   30   2.1  
gi|46877064 plasticity related gene 3 [Homo sapiens]                   30   2.1  
gi|7656981 claudin 15 [Homo sapiens]                                   29   2.8  
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...    28   4.7  
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]            28   6.2  

>gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score =  451 bits (1160), Expect = e-127
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60
           MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA
Sbjct: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60

Query: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA
Sbjct: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
           CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL
Sbjct: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180

Query: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221
           LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI
Sbjct: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221


>gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo
           sapiens]
          Length = 221

 Score =  451 bits (1160), Expect = e-127
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60
           MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA
Sbjct: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60

Query: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA
Sbjct: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
           CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL
Sbjct: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180

Query: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221
           LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI
Sbjct: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221


>gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo
           sapiens]
          Length = 221

 Score =  451 bits (1160), Expect = e-127
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60
           MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA
Sbjct: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60

Query: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA
Sbjct: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
           CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL
Sbjct: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180

Query: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221
           LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI
Sbjct: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221


>gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score =  451 bits (1160), Expect = e-127
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60
           MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA
Sbjct: 1   MLTLEDKDMKGFSWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA 60

Query: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA
Sbjct: 61  KCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
           CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL
Sbjct: 121 CAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180

Query: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221
           LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI
Sbjct: 181 LSTSQSMEEDHGSLYLDNLESLGGEPSSVQKETQVTAETVI 221


>gi|122937323 transmembrane protein 202 [Homo sapiens]
          Length = 273

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/172 (22%), Positives = 78/172 (45%), Gaps = 18/172 (10%)

Query: 25  YLIILVVSIFPF-WVRLTNEESHEVFFSGLFENCFNAKCWK--PRPLSIYIILGRVFLLS 81
           + +++++++ P  WV+    ++    ++GL+  C +  CW   P+P   Y+   R F L 
Sbjct: 66  FSLLMLIAMSPLNWVQFLVIKNGLELYAGLWTLCNHELCWSHTPKP-PYYLQYSRAFFLI 124

Query: 82  AVFLAFVTTFIMMPFASEFFPR---TWKQNFVLACISFFTGACAFLALVLHALEIKALRM 138
           +VF   + T +   F+S    R   T   +  ++ +SF +  C  L L L   ++     
Sbjct: 125 SVFT--ILTGLGWLFSSWILNRGSMTTNLDLKVSMLSFISATCLLLCLNLFVAQVH--WH 180

Query: 139 KLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVCPCWHLLSTSQSMEED 190
               ++  +LW YY+       ++ AG I L+        +L S S + +E+
Sbjct: 181 TRDAMESDLLWTYYLNWCSDIFYMFAGIISLLN-------YLTSRSPACDEN 225


>gi|62000698 transmembrane protein 225 [Homo sapiens]
          Length = 225

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 41/209 (19%), Positives = 82/209 (39%), Gaps = 19/209 (9%)

Query: 13  SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
           SWA+V        L+++ +++   WV L +E+         +  C  A  W    L +  
Sbjct: 18  SWAVV--------LMVMGITLDK-WVELISEDERAKMNHSPWMMCCPA-LWPEDDLKVV- 66

Query: 73  ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHALE 132
              R+ + S++ L+F+   I+    +   P+          +SFF+G     AL+L+  +
Sbjct: 67  ---RIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNK 123

Query: 133 IKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTI----CLIQEMVCPCWHLLSTSQSME 188
           +K     +    + + W  Y     +F   V G +    C +    C C ++  +    +
Sbjct: 124 LKQ-GQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECK 182

Query: 189 EDHGSLYLDNLESLGGEPSSVQKETQVTA 217
           E   S+   +L      P S+ +   V +
Sbjct: 183 ESENSIEDISLPECTAMPRSIVRAHTVNS 211


>gi|188528658 transmembrane protein 182 [Homo sapiens]
          Length = 229

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 14/120 (11%)

Query: 70  IYIILGRVFLLSAVFLAFVTTFIMM---PFASEFFPRTWKQNFVLACISFFTGACAFLAL 126
           IY     V +L  V    + +F+++   PFAS F  +    +++ A I F      ++  
Sbjct: 111 IYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIW 170

Query: 127 VLHALEIKALR-MKLGP-LQF--SVL--WPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
           V    ++++ R MK+   L F  SVL  W +++   GIF  ++AG + L+       WH+
Sbjct: 171 VQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVG-----WHI 225


>gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
          Length = 346

 Score = 32.3 bits (72), Expect = 0.33
 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 24/137 (17%)

Query: 57  CFNAKCWKPRPLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFF--PRTWKQNFVLACI 114
           CF+ K WKP  + ++ +    FLL           I +PF ++++   R W    +   +
Sbjct: 41  CFHMKTWKPSTVYLFNLAVADFLL----------MICLPFRTDYYLRRRHWAFGDIPCRV 90

Query: 115 SFFTGACAFLALVLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMV 174
             FT A      ++    + A R       F V+ P++ +   I   + AG +C +  +V
Sbjct: 91  GLFTLAMNRAGSIVFLTVVAADR------YFKVVHPHHAVN-TISTRVAAGIVCTLWALV 143

Query: 175 CPCWHLLSTSQSMEEDH 191
                +L T   + E+H
Sbjct: 144 -----ILGTVYLLLENH 155


>gi|116812579 transmembrane BAX inhibitor motif containing 4 [Homo
           sapiens]
          Length = 238

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 16/95 (16%)

Query: 67  PLSIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLAL 126
           PL++Y++ G   LL A+ +A V TF  +            Q F+L    FF        L
Sbjct: 95  PLNLYLLFGFT-LLEALTVAVVVTFYDVYIIL--------QAFILTTTVFF-------GL 138

Query: 127 VLHALEIKALRMKLGPLQFSVLWPYYVLGFGIFLF 161
            ++ L+ K    K G   F++LW   + GF  F F
Sbjct: 139 TVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFF 173


>gi|28144908 clarin 1 isoform a [Homo sapiens]
          Length = 232

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 91  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 146

Query: 121 CAFLALVLHALEIK 134
           C  L ++L A E+K
Sbjct: 147 CGCLVMILFASEVK 160


>gi|16506281 clarin 1 isoform c [Homo sapiens]
          Length = 120

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 15  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 70

Query: 121 CAFLALVLHALEIK 134
           C  L ++L A E+K
Sbjct: 71  CGCLVMILFASEVK 84


>gi|46877066 plasticity related gene 3 [Homo sapiens]
          Length = 325

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 24/119 (20%), Positives = 51/119 (42%), Gaps = 4/119 (3%)

Query: 13  SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
           S++I+P    +  +I+    +  ++   T  ++ +V   G F  C +    KP P +   
Sbjct: 10  SYSIIPCFIFVELVIMAGTVLLAYYFECT--DTFQVHIQGFF--CQDGDLMKPYPGTEEE 65

Query: 73  ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHAL 131
                 +L  V  A  T  I +   S +F ++ +++ +    +  TG C +L  +L  +
Sbjct: 66  SFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAQEKTILTGECCYLNPLLRRI 124


>gi|46877064 plasticity related gene 3 [Homo sapiens]
          Length = 325

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 24/119 (20%), Positives = 51/119 (42%), Gaps = 4/119 (3%)

Query: 13  SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
           S++I+P    +  +I+    +  ++   T  ++ +V   G F  C +    KP P +   
Sbjct: 10  SYSIIPCFIFVELVIMAGTVLLAYYFECT--DTFQVHIQGFF--CQDGDLMKPYPGTEEE 65

Query: 73  ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHAL 131
                 +L  V  A  T  I +   S +F ++ +++ +    +  TG C +L  +L  +
Sbjct: 66  SFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAQEKTILTGECCYLNPLLRRI 124


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 36/175 (20%), Positives = 68/175 (38%), Gaps = 20/175 (11%)

Query: 20  LTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNA---------KCWK-PRPLS 69
           + ++G L++ V     +W R++    + +  + +FEN + +          CW+ P  L+
Sbjct: 12  MATVGLLMLGVTLPNSYW-RVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLA 70

Query: 70  I--YIILGRVFLLSAVFLAFVTTFIMMP------FASEFFPRTWKQNFVLACISFFTGAC 121
           +  YI   R  +++A+ L F+   + +              R  K       +    G C
Sbjct: 71  LSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGIC 130

Query: 122 AFLALVLHALEI-KALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTICLIQEMVC 175
             +A+  +A  I +     L P     L P   LG+   L  + G +CL     C
Sbjct: 131 GMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSACCC 185


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 10/68 (14%)

Query: 110  VLACISFFTGACAFLALVLHALEI-KALR----MKLGPLQFSVLWPYYVLGFGIFLFIVA 164
            V+A +  F   C F   +L AL + +AL     +  GP++F     YY+LG+G+  FI  
Sbjct: 2441 VIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRF-----YYMLGWGVPAFITG 2495

Query: 165  GTICLIQE 172
              + L  E
Sbjct: 2496 LAVGLDPE 2503


>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
          Length = 1053

 Score = 28.1 bits (61), Expect = 6.2
 Identities = 13/36 (36%), Positives = 23/36 (63%)

Query: 177 CWHLLSTSQSMEEDHGSLYLDNLESLGGEPSSVQKE 212
           C + L+  Q   +D+GS YL  +E +G + +S++KE
Sbjct: 344 CEYKLTGLQQQCDDYGSSYLGVIELIGEKETSLRKE 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.142    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,756,017
Number of Sequences: 37866
Number of extensions: 299943
Number of successful extensions: 882
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 16
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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