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Search of human proteins with 239746419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239746419 PREDICTED: hypothetical protein XP_002344218 [Homo
sapiens]
(532 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239746419 PREDICTED: hypothetical protein XP_002344218 [Homo ... 1098 0.0
gi|239757417 PREDICTED: similar to hCG2019710 [Homo sapiens] 1046 0.0
gi|239751934 PREDICTED: hypothetical protein XP_002348043 [Homo ... 1046 0.0
gi|169217521 PREDICTED: similar to signal-regulatory protein bet... 143 4e-34
gi|18426911 signal-regulatory protein alpha precursor [Homo sapi... 117 3e-26
gi|91105767 signal-regulatory protein alpha precursor [Homo sapi... 117 3e-26
gi|91105764 signal-regulatory protein alpha precursor [Homo sapi... 117 3e-26
gi|209529703 signal-regulatory protein beta 1 isoform 3 precurso... 117 3e-26
gi|144953876 signal-regulatory protein beta 1 isoform 1 precurso... 116 4e-26
gi|94538339 signal-regulatory protein gamma isoform 3 precursor ... 114 2e-25
gi|94538335 signal-regulatory protein gamma isoform 1 precursor ... 114 2e-25
gi|144953878 signal-regulatory protein beta 1 isoform 2 precurso... 114 3e-25
gi|239751927 PREDICTED: similar to signal-regulatory protein bet... 113 5e-25
gi|94538337 signal-regulatory protein gamma isoform 2 precursor ... 113 5e-25
gi|30425382 signal-regulatory protein delta [Homo sapiens] 79 8e-15
gi|171906611 signal-regulatory protein beta 2 isoform 1 [Homo sa... 54 4e-07
gi|198386341 signal-regulatory protein beta 2 isoform 2 [Homo sa... 53 6e-07
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 41 0.003
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ... 40 0.005
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 40 0.007
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 38 0.026
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 37 0.045
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 37 0.045
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 37 0.045
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 37 0.045
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 36 0.077
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 36 0.10
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 36 0.10
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 35 0.13
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 35 0.13
>gi|239746419 PREDICTED: hypothetical protein XP_002344218 [Homo
sapiens]
Length = 532
Score = 1098 bits (2841), Expect = 0.0
Identities = 532/532 (100%), Positives = 532/532 (100%)
Query: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF
Sbjct: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
Query: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT
Sbjct: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
Query: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG
Sbjct: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
Query: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY
Sbjct: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
Query: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVVWRAPYPALFSTG 300
NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVVWRAPYPALFSTG
Sbjct: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVVWRAPYPALFSTG 300
Query: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN
Sbjct: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
Query: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG
Sbjct: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
Query: 421 EEELRVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
EEELRVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT
Sbjct: 421 EEELRVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
Query: 481 GTYNCVKFWKGGPDMELKSGPGTELSVHSEYSVGLLRPPVCDNKSIVTPSIH 532
GTYNCVKFWKGGPDMELKSGPGTELSVHSEYSVGLLRPPVCDNKSIVTPSIH
Sbjct: 481 GTYNCVKFWKGGPDMELKSGPGTELSVHSEYSVGLLRPPVCDNKSIVTPSIH 532
>gi|239757417 PREDICTED: similar to hCG2019710 [Homo sapiens]
Length = 651
Score = 1046 bits (2706), Expect = 0.0
Identities = 506/508 (99%), Positives = 508/508 (100%)
Query: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF
Sbjct: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
Query: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT
Sbjct: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
Query: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG
Sbjct: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
Query: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY
Sbjct: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
Query: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVVWRAPYPALFSTG 300
NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYL+EPMTVVWRAPYPALFSTG
Sbjct: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLREPMTVVWRAPYPALFSTG 300
Query: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN
Sbjct: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
Query: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG
Sbjct: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
Query: 421 EEELRVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
EEEL+VIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT
Sbjct: 421 EEELQVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
Query: 481 GTYNCVKFWKGGPDMELKSGPGTELSVH 508
GTYNCVKFWKGGPDMELKSGPGTELSVH
Sbjct: 481 GTYNCVKFWKGGPDMELKSGPGTELSVH 508
Score = 84.3 bits (207), Expect = 2e-16
Identities = 41/82 (50%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Query: 427 IQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCV 486
+ P +WF+G GQ+LIYS K H P++ ISD KRN+TD+S+ I+SIT + GTY C+
Sbjct: 544 VGPIQWFRGACPGQKLIYSPKRCHSPRVTTISDQRKRNSTDYSIRISSITLEDAGTYYCM 603
Query: 487 KFWKGGP-DMELKSGPGTELSV 507
K + P ++E+KSGPGT++SV
Sbjct: 604 KLRRAIPANVEIKSGPGTQMSV 625
>gi|239751934 PREDICTED: hypothetical protein XP_002348043 [Homo
sapiens]
Length = 651
Score = 1046 bits (2706), Expect = 0.0
Identities = 506/508 (99%), Positives = 508/508 (100%)
Query: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF
Sbjct: 1 MATTPGRALGSLLPTLLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDF 60
Query: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT
Sbjct: 61 NVTWLKDSDEHPASAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHRALAEPLKT 120
Query: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG
Sbjct: 121 TMNLSQATRNPDGTYSLEHTWQAEATLEEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
Query: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY
Sbjct: 181 QSVQPYKLQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHTY 240
Query: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVVWRAPYPALFSTG 300
NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYL+EPMTVVWRAPYPALFSTG
Sbjct: 241 NVTSSVLVPLMDDDVFSHVVCHVEHKLTWFFQKTTGLDQYLREPMTVVWRAPYPALFSTG 300
Query: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN
Sbjct: 301 TTPVTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKN 360
Query: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG
Sbjct: 361 NDRSYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
Query: 421 EEELRVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
EEEL+VIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT
Sbjct: 421 EEELQVIQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANT 480
Query: 481 GTYNCVKFWKGGPDMELKSGPGTELSVH 508
GTYNCVKFWKGGPDMELKSGPGTELSVH
Sbjct: 481 GTYNCVKFWKGGPDMELKSGPGTELSVH 508
Score = 84.3 bits (207), Expect = 2e-16
Identities = 41/82 (50%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Query: 427 IQPEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCV 486
+ P +WF+G GQ+LIYS K H P++ ISD KRN+TD+S+ I+SIT + GTY C+
Sbjct: 544 VGPIQWFRGACPGQKLIYSPKRCHSPRVTTISDQRKRNSTDYSIRISSITLEDAGTYYCM 603
Query: 487 KFWKGGP-DMELKSGPGTELSV 507
K + P ++E+KSGPGT++SV
Sbjct: 604 KLRRAIPANVEIKSGPGTQMSV 625
>gi|169217521 PREDICTED: similar to signal-regulatory protein beta 1
[Homo sapiens]
Length = 160
Score = 143 bits (360), Expect = 4e-34
Identities = 76/142 (53%), Positives = 92/142 (64%), Gaps = 27/142 (19%)
Query: 417 GAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSSKGGH 450
G AGE+EL+VIQPEK WF+G G+ELIY+ K GH
Sbjct: 9 GVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGH 68
Query: 451 FPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGP-DMELKSGPGTELSVHS 509
FP++ +S++TKRNN DFS+ I++IT A+ GTY CVKF KG P D+E KSG GTELSV
Sbjct: 69 FPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRG 128
Query: 510 EYSVGLLRPPVCDNKSIVTPSI 531
EYSVGLL P VCDN SI+T SI
Sbjct: 129 EYSVGLLCPLVCDNNSIITLSI 150
>gi|18426911 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 117 bits (292), Expect = 3e-26
Identities = 72/161 (44%), Positives = 91/161 (56%), Gaps = 34/161 (21%)
Query: 388 MEHEGQPPKRAN--LVLSTAAHTAYKPIGSTGAAGEEELRVIQPEK-------------- 431
ME G P R L L AA A+ +G AGEEEL+VIQP+K
Sbjct: 1 MEPAGPAPGRLGPLLCLLLAASCAW-----SGVAGEEELQVIQPDKSVLVAAGETATLRC 55
Query: 432 ------------WFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRAN 479
WF+G G+ELIY+ K GHFP++ +SD+TKRNN DFS+ I +IT A+
Sbjct: 56 TATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPAD 115
Query: 480 TGTYNCVKFWKGGP-DMELKSGPGTELSVHSEYSVGLLRPP 519
GTY CVKF KG P D+E KSG GTELSV ++ S ++ P
Sbjct: 116 AGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGP 156
Score = 103 bits (257), Expect = 4e-22
Identities = 75/236 (31%), Positives = 108/236 (45%), Gaps = 30/236 (12%)
Query: 188 LQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH--TYNVTSS 245
+ GP R+ P + T S GFS +T+ W KN +EL + QT+V G +Y++ S+
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHST 212
Query: 246 VLVPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTP 303
V L +DV S V+C V H + T L + ++ P T+ T
Sbjct: 213 AKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTL-----------EVTQQ 261
Query: 304 VTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDR 363
RA V VTC V++FYPQ + L WLE+ + + T+ +N D
Sbjct: 262 PVRAENQ-------------VNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDG 308
Query: 364 SYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAA 419
+Y LLVN S + LTC +EH+GQP + L +AH K GS AA
Sbjct: 309 TYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHP--KEQGSNTAA 362
Score = 59.3 bits (142), Expect = 8e-09
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 29 LTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASAQRLVPDNGGNDF- 87
++GP+ R +P +V F C + F+ RD + W K+ +E + P +
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSP----RDITLKWFKNGNELSDFQTNVDPVGESVSYS 208
Query: 88 ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDGTYSLEHTWQAEAT 146
I S A V LTR+DV S++ CEV H L +PL+ T NLS+ R P +LE T Q
Sbjct: 209 IHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPP---TLEVTQQPVRA 265
Query: 147 LEEREFACWV 156
+ C V
Sbjct: 266 ENQVNVTCQV 275
>gi|91105767 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 117 bits (292), Expect = 3e-26
Identities = 72/161 (44%), Positives = 91/161 (56%), Gaps = 34/161 (21%)
Query: 388 MEHEGQPPKRAN--LVLSTAAHTAYKPIGSTGAAGEEELRVIQPEK-------------- 431
ME G P R L L AA A+ +G AGEEEL+VIQP+K
Sbjct: 1 MEPAGPAPGRLGPLLCLLLAASCAW-----SGVAGEEELQVIQPDKSVLVAAGETATLRC 55
Query: 432 ------------WFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRAN 479
WF+G G+ELIY+ K GHFP++ +SD+TKRNN DFS+ I +IT A+
Sbjct: 56 TATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPAD 115
Query: 480 TGTYNCVKFWKGGP-DMELKSGPGTELSVHSEYSVGLLRPP 519
GTY CVKF KG P D+E KSG GTELSV ++ S ++ P
Sbjct: 116 AGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGP 156
Score = 103 bits (257), Expect = 4e-22
Identities = 75/236 (31%), Positives = 108/236 (45%), Gaps = 30/236 (12%)
Query: 188 LQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH--TYNVTSS 245
+ GP R+ P + T S GFS +T+ W KN +EL + QT+V G +Y++ S+
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHST 212
Query: 246 VLVPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTP 303
V L +DV S V+C V H + T L + ++ P T+ T
Sbjct: 213 AKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTL-----------EVTQQ 261
Query: 304 VTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDR 363
RA V VTC V++FYPQ + L WLE+ + + T+ +N D
Sbjct: 262 PVRAENQ-------------VNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDG 308
Query: 364 SYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAA 419
+Y LLVN S + LTC +EH+GQP + L +AH K GS AA
Sbjct: 309 TYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHP--KEQGSNTAA 362
Score = 59.3 bits (142), Expect = 8e-09
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 29 LTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASAQRLVPDNGGNDF- 87
++GP+ R +P +V F C + F+ RD + W K+ +E + P +
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSP----RDITLKWFKNGNELSDFQTNVDPVGESVSYS 208
Query: 88 ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDGTYSLEHTWQAEAT 146
I S A V LTR+DV S++ CEV H L +PL+ T NLS+ R P +LE T Q
Sbjct: 209 IHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPP---TLEVTQQPVRA 265
Query: 147 LEEREFACWV 156
+ C V
Sbjct: 266 ENQVNVTCQV 275
>gi|91105764 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 117 bits (292), Expect = 3e-26
Identities = 72/161 (44%), Positives = 91/161 (56%), Gaps = 34/161 (21%)
Query: 388 MEHEGQPPKRAN--LVLSTAAHTAYKPIGSTGAAGEEELRVIQPEK-------------- 431
ME G P R L L AA A+ +G AGEEEL+VIQP+K
Sbjct: 1 MEPAGPAPGRLGPLLCLLLAASCAW-----SGVAGEEELQVIQPDKSVLVAAGETATLRC 55
Query: 432 ------------WFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRAN 479
WF+G G+ELIY+ K GHFP++ +SD+TKRNN DFS+ I +IT A+
Sbjct: 56 TATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPAD 115
Query: 480 TGTYNCVKFWKGGP-DMELKSGPGTELSVHSEYSVGLLRPP 519
GTY CVKF KG P D+E KSG GTELSV ++ S ++ P
Sbjct: 116 AGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGP 156
Score = 103 bits (257), Expect = 4e-22
Identities = 75/236 (31%), Positives = 108/236 (45%), Gaps = 30/236 (12%)
Query: 188 LQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH--TYNVTSS 245
+ GP R+ P + T S GFS +T+ W KN +EL + QT+V G +Y++ S+
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHST 212
Query: 246 VLVPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTP 303
V L +DV S V+C V H + T L + ++ P T+ T
Sbjct: 213 AKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTL-----------EVTQQ 261
Query: 304 VTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDR 363
RA V VTC V++FYPQ + L WLE+ + + T+ +N D
Sbjct: 262 PVRAENQ-------------VNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDG 308
Query: 364 SYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAA 419
+Y LLVN S + LTC +EH+GQP + L +AH K GS AA
Sbjct: 309 TYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHP--KEQGSNTAA 362
Score = 59.3 bits (142), Expect = 8e-09
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 29 LTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASAQRLVPDNGGNDF- 87
++GP+ R +P +V F C + F+ RD + W K+ +E + P +
Sbjct: 153 VSGPAARATPQHTVSFTCESHGFSP----RDITLKWFKNGNELSDFQTNVDPVGESVSYS 208
Query: 88 ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDGTYSLEHTWQAEAT 146
I S A V LTR+DV S++ CEV H L +PL+ T NLS+ R P +LE T Q
Sbjct: 209 IHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPP---TLEVTQQPVRA 265
Query: 147 LEEREFACWV 156
+ C V
Sbjct: 266 ENQVNVTCQV 275
>gi|209529703 signal-regulatory protein beta 1 isoform 3 precursor
[Homo sapiens]
Length = 398
Score = 117 bits (292), Expect = 3e-26
Identities = 63/131 (48%), Positives = 81/131 (61%), Gaps = 27/131 (20%)
Query: 416 TGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSSKGG 449
TG AGEEEL+VIQP+K WF+G G+ELIY+ K G
Sbjct: 25 TGVAGEEELQVIQPDKSISVAAGESATLHCTVTSLIPVGPIQWFRGAGPGRELIYNQKEG 84
Query: 450 HFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGPD-MELKSGPGTELSVH 508
HFP++ +SD+TKRNN DFS+ I++IT A+ GTY CVKF KG PD +E KSG GTELSV
Sbjct: 85 HFPRVTTVSDLTKRNNMDFSIRISNITPADAGTYYCVKFRKGSPDHVEFKSGAGTELSVR 144
Query: 509 SEYSVGLLRPP 519
++ S ++ P
Sbjct: 145 AKPSAPVVSGP 155
Score = 105 bits (263), Expect = 8e-23
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 30/237 (12%)
Query: 188 LQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH--TYNVTSS 245
+ GP R+ P + T S GFS +T+ W KN +EL + QT+V +G +Y++ S+
Sbjct: 152 VSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHST 211
Query: 246 VLVPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTP 303
V L +DV S V+C V H + T L + ++ P T+ T
Sbjct: 212 AKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTL-----------EVTQQ 260
Query: 304 VTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDR 363
RA V VTC V++FYPQ + L WLE+ + + TL +N D
Sbjct: 261 PVRAENQ-------------VNVTCQVRKFYPQRLQLTWLENGNVSRTETASTLTENKDG 307
Query: 364 SYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAHTAYKPIGSTGAAG 420
+Y LLVN S + LTC +EH+GQP + L +AH K GS A G
Sbjct: 308 TYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHP--KEQGSNTAPG 362
Score = 60.1 bits (144), Expect = 5e-09
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 29 LTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASAQRLVPDNGGNDF- 87
++GP+ R +P +V F C + F+ RD + W K+ +E + P +
Sbjct: 152 VSGPAARATPQHTVSFTCESHGFSP----RDITLKWFKNGNELSDFQTNVDPAGDSVSYS 207
Query: 88 ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDGTYSLEHTWQAEAT 146
I S A V LTR+DV S++ CEV H L +PL+ T NLS+ R P +LE T Q
Sbjct: 208 IHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPP---TLEVTQQPVRA 264
Query: 147 LEEREFACWV 156
+ C V
Sbjct: 265 ENQVNVTCQV 274
>gi|144953876 signal-regulatory protein beta 1 isoform 1 precursor
[Homo sapiens]
Length = 398
Score = 116 bits (291), Expect = 4e-26
Identities = 62/131 (47%), Positives = 81/131 (61%), Gaps = 27/131 (20%)
Query: 416 TGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSSKGG 449
TG AGE+EL+VIQPEK WF+G G+ELIY+ K G
Sbjct: 25 TGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEG 84
Query: 450 HFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGP-DMELKSGPGTELSVH 508
HFP++ +S++TKRNN DFS+ I++IT A+ GTY CVKF KG P D+E KSG GTELSV
Sbjct: 85 HFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVR 144
Query: 509 SEYSVGLLRPP 519
++ S ++ P
Sbjct: 145 AKPSAPVVSGP 155
Score = 95.9 bits (237), Expect = 8e-20
Identities = 67/224 (29%), Positives = 101/224 (45%), Gaps = 28/224 (12%)
Query: 188 LQGPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHT--YNVTSS 245
+ GP R+ P + T S GFS +T+ W KN +EL + QT+V +G + Y++ S+
Sbjct: 152 VSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHST 211
Query: 246 VLVPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTP 303
V L DV S V+C + H + T L + ++ P T+
Sbjct: 212 ARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTL---------------E 256
Query: 304 VTRASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDR 363
VT+ Q + VTC V FYP+ + L WLE+ + + TL +N D
Sbjct: 257 VTQ---------QPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDG 307
Query: 364 SYTLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAH 407
+Y LLVN + VLTC +EH+GQ + L +AH
Sbjct: 308 TYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAH 351
Score = 60.1 bits (144), Expect = 5e-09
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 29 LTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASAQRLVPDNGGNDF- 87
++GP+ R +P +V F C + F+ RD + W K+ +E + P +
Sbjct: 152 VSGPAVRATPEHTVSFTCESHGFSP----RDITLKWFKNGNELSDFQTNVDPAGDSVSYS 207
Query: 88 ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDGTYSLEHTWQAEAT 146
I S A V LTR DV S++ CE+ H L +PL+ T NLS+A R P +LE T Q
Sbjct: 208 IHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPP---TLEVTQQPMRA 264
Query: 147 LEEREFACWV 156
+ C V
Sbjct: 265 ENQANVTCQV 274
>gi|94538339 signal-regulatory protein gamma isoform 3 precursor
[Homo sapiens]
Length = 276
Score = 114 bits (286), Expect = 2e-25
Identities = 61/134 (45%), Positives = 83/134 (61%), Gaps = 27/134 (20%)
Query: 413 IGSTGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSS 446
+G T AGEEEL++IQPEK WF+G G+ELIY+
Sbjct: 21 LGLTEVAGEEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQ 80
Query: 447 KGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGPD-MELKSGPGTEL 505
K GHFP++ +SD+TKRNN DFS+ I+SIT A+ GTY CVKF KG P+ +E KSGPGTE+
Sbjct: 81 KEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEM 140
Query: 506 SVHSEYSVGLLRPP 519
++ ++ S ++ P
Sbjct: 141 ALGAKPSAPVVLGP 154
Score = 57.0 bits (136), Expect = 4e-08
Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 8/118 (6%)
Query: 16 LLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASA 75
+ LG P + GP+ RT+P +V F C + F+ RD + W K+ +E
Sbjct: 140 MALGAKPSAPVV--LGPAARTTPEHTVSFTCESHGFS----PRDITLKWFKNGNELSDFQ 193
Query: 76 QRLVPDNGGNDF-ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNP 131
+ P + I S A V L DV S++ CEV H L +PL+ T NLS+A R P
Sbjct: 194 TNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRGP 251
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 190 GPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHT--YNVTSSVL 247
GP R+ P + T S GFS +T+ W KN +EL + QT+V +G + Y++ S+
Sbjct: 153 GPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTAR 212
Query: 248 VPLMDDDVFSHVVCHVEH 265
V L DV S V+C V H
Sbjct: 213 VVLDPWDVRSQVICEVAH 230
>gi|94538335 signal-regulatory protein gamma isoform 1 precursor
[Homo sapiens]
Length = 387
Score = 114 bits (286), Expect = 2e-25
Identities = 61/134 (45%), Positives = 83/134 (61%), Gaps = 27/134 (20%)
Query: 413 IGSTGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSS 446
+G T AGEEEL++IQPEK WF+G G+ELIY+
Sbjct: 21 LGLTEVAGEEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQ 80
Query: 447 KGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGPD-MELKSGPGTEL 505
K GHFP++ +SD+TKRNN DFS+ I+SIT A+ GTY CVKF KG P+ +E KSGPGTE+
Sbjct: 81 KEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEM 140
Query: 506 SVHSEYSVGLLRPP 519
++ ++ S ++ P
Sbjct: 141 ALGAKPSAPVVLGP 154
Score = 97.4 bits (241), Expect = 3e-20
Identities = 69/222 (31%), Positives = 102/222 (45%), Gaps = 28/222 (12%)
Query: 190 GPLQRSEPGTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGHT--YNVTSSVL 247
GP R+ P + T S GFS +T+ W KN +EL + QT+V +G + Y++ S+
Sbjct: 153 GPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTAR 212
Query: 248 VPLMDDDVFSHVVCHVEHKLTWF--FQKTTGLDQYLQEPMTVVWRAPYPALFSTGTTPVT 305
V L DV S V+C V H + T L + ++ P T+ VT
Sbjct: 213 VVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTL---------------EVT 257
Query: 306 RASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDRSY 365
+ Q + V VTC V++FYPQ++ L W E+ + + TL +N D +Y
Sbjct: 258 Q---------QPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTY 308
Query: 366 TLEKLLLVNASVQGPERVLTCMMEHEGQPPKRANLVLSTAAH 407
LVN S Q + VLTC ++H+GQ L L H
Sbjct: 309 NWTSWFLVNISDQRDDVVLTCQVKHDGQLAVSKRLALEVTVH 350
Score = 56.2 bits (134), Expect = 7e-08
Identities = 46/143 (32%), Positives = 65/143 (45%), Gaps = 11/143 (7%)
Query: 16 LLLGLTAGQPFISLTGPSHRTSPGDSVPFNCTAVPFNSQDFSRDFNVTWLKDSDEHPASA 75
+ LG P + GP+ RT+P +V F C + F+ RD + W K+ +E
Sbjct: 140 MALGAKPSAPVV--LGPAARTTPEHTVSFTCESHGFS----PRDITLKWFKNGNELSDFQ 193
Query: 76 QRLVPDNGGNDF-ITSKAWVTLTRQDVSSEITCEVTHRAL-AEPLKTTMNLSQATRNPDG 133
+ P + I S A V L DV S++ CEV H L +PL+ T NLS+A R P
Sbjct: 194 TNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPP- 252
Query: 134 TYSLEHTWQAEATLEEREFACWV 156
+LE T Q + C V
Sbjct: 253 --TLEVTQQPMRVGNQVNVTCQV 273
>gi|144953878 signal-regulatory protein beta 1 isoform 2 precursor
[Homo sapiens]
Length = 181
Score = 114 bits (284), Expect = 3e-25
Identities = 60/119 (50%), Positives = 75/119 (63%), Gaps = 27/119 (22%)
Query: 416 TGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSSKGG 449
TG AGE+EL+VIQPEK WF+G G+ELIY+ K G
Sbjct: 25 TGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEG 84
Query: 450 HFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGP-DMELKSGPGTELSV 507
HFP++ +S++TKRNN DFS+ I++IT A+ GTY CVKF KG P D+E KSG GTELSV
Sbjct: 85 HFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSV 143
>gi|239751927 PREDICTED: similar to signal-regulatory protein beta 1
[Homo sapiens]
Length = 136
Score = 113 bits (282), Expect = 5e-25
Identities = 59/121 (48%), Positives = 76/121 (62%), Gaps = 27/121 (22%)
Query: 417 GAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSSKGGH 450
G AGE+EL+VIQPEK WF+G G+ELIY+ K GH
Sbjct: 9 GVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGH 68
Query: 451 FPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGP-DMELKSGPGTELSVHS 509
FP++ +S++TKRNN DFS+ I++IT A+ GTY CVKF KG P D+E KSG GTELSV +
Sbjct: 69 FPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRA 128
Query: 510 E 510
+
Sbjct: 129 D 129
>gi|94538337 signal-regulatory protein gamma isoform 2 precursor
[Homo sapiens]
Length = 170
Score = 113 bits (282), Expect = 5e-25
Identities = 59/122 (48%), Positives = 77/122 (63%), Gaps = 27/122 (22%)
Query: 413 IGSTGAAGEEELRVIQPEK--------------------------WFKGTETGQELIYSS 446
+G T AGEEEL++IQPEK WF+G G+ELIY+
Sbjct: 21 LGLTEVAGEEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQ 80
Query: 447 KGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKFWKGGPD-MELKSGPGTEL 505
K GHFP++ +SD+TKRNN DFS+ I+SIT A+ GTY CVKF KG P+ +E KSGPGTE+
Sbjct: 81 KEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEM 140
Query: 506 SV 507
++
Sbjct: 141 AL 142
>gi|30425382 signal-regulatory protein delta [Homo sapiens]
Length = 197
Score = 79.3 bits (194), Expect = 8e-15
Identities = 43/91 (47%), Positives = 55/91 (60%), Gaps = 4/91 (4%)
Query: 429 PEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKF 488
P WFKGT ++LIY+ K G+FP++ I D TK NTDFS I I+ A+ GTY CVKF
Sbjct: 61 PVLWFKGTGPNRKLIYNFKQGNFPRVKEIGDTTKPGNTDFSTRIREISLADAGTYYCVKF 120
Query: 489 WKGGPDMELKSGPGTELSVHSEYSVGLLRPP 519
KG E +SG GT++ V + RPP
Sbjct: 121 IKGRAIKEYQSGRGTQVFVTEQNP----RPP 147
>gi|171906611 signal-regulatory protein beta 2 isoform 1 [Homo
sapiens]
Length = 342
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 431 KWFKGTETGQELIYSSKGGHFPKIA-CISDITKRNNTDFSMCITSITRANTGTYNCVKFW 489
KW K + Q+ IY+ K G FP + I ++ N D+S+ I ++TR +TGTY+CV+F
Sbjct: 72 KWVKVSTQDQQEIYNFKRGSFPGVMPMIQRTSEPLNCDYSIYIHNVTREHTGTYHCVRFD 131
Query: 490 KGGPDMELKSGPGTELSV 507
E+KS GT + V
Sbjct: 132 GLSEHSEMKSDEGTSVLV 149
Score = 53.1 bits (126), Expect = 6e-07
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 429 PEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKF 488
P +WF+G +E IY+ G PK + + +N DFS+ + +++ + GTY CVKF
Sbjct: 190 PIRWFQGAGLSREAIYNFGGISHPKETAV----QASNNDFSILLQNVSSEDAGTYYCVKF 245
Query: 489 WKGGPDMELKSGPGTELSVHSE 510
+ P+ + SG GT L V ++
Sbjct: 246 QR-KPNRQYLSGQGTSLKVKAK 266
>gi|198386341 signal-regulatory protein beta 2 isoform 2 [Homo
sapiens]
Length = 244
Score = 53.1 bits (126), Expect = 6e-07
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 429 PEKWFKGTETGQELIYSSKGGHFPKIACISDITKRNNTDFSMCITSITRANTGTYNCVKF 488
P +WF+G +E IY+ G PK + + +N DFS+ + +++ + GTY CVKF
Sbjct: 92 PIRWFQGAGLSREAIYNFGGISHPKETAV----QASNNDFSILLQNVSSEDAGTYYCVKF 147
Query: 489 WKGGPDMELKSGPGTELSVHSE 510
+ P+ + SG GT L V ++
Sbjct: 148 QR-KPNRQYLSGQGTSLKVKAK 168
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 40.8 bits (94), Expect = 0.003
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 324 VAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDRSYTLEKLLLVNASVQGPERV 383
+ VTC FYP+N+ L W +D +L Q D + T + + QG E+
Sbjct: 221 ITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIR-QGEEQR 279
Query: 384 LTCMMEHEG 392
TC MEH G
Sbjct: 280 FTCYMEHSG 288
>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
sapiens]
Length = 264
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 326 VTCLVQRFYPQNVHLAWLEDCHTLK-GTEQPTLKKNNDRSYTLEKLLLVNASVQGPERVL 384
+ CL+ FYP V +AW D +K G E T K ++ Y L + R
Sbjct: 184 LVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSY 243
Query: 385 TCMMEHEG 392
+C + HEG
Sbjct: 244 SCQVTHEG 251
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 39.7 bits (91), Expect = 0.007
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 4/99 (4%)
Query: 324 VAVTCLVQRFYPQNVHLAWLEDCHTLKGTEQPTLKKNNDRSYTLEKLLLVNASVQGPERV 383
+ VTC FYP N+ L+W +D +L Q D + T + + QG E+
Sbjct: 221 ITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRI-CQGEEQR 279
Query: 384 LTCMMEHEGQ---PPKRANLVLSTAAHTAYKPIGSTGAA 419
TC MEH G P + VL +H + + AA
Sbjct: 280 FTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAA 318
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 37.7 bits (86), Expect = 0.026
Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 10/148 (6%)
Query: 251 MDDDVF---SHVVCHVEHKLTWFFQKTTGLDQYLQEPMTVV-WRAPYPALFSTGTTPVTR 306
+DD +F H VE + W + + +LQ ++ W + F T
Sbjct: 53 VDDQLFVFYDHESRRVEPRTPWVSSRISS-QMWLQLSQSLKGWDHMFTVDFWTIMENHNH 111
Query: 307 ASTPGVFHSQVLLFSCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRS 364
+ P + + S + + C +YPQN+ + WL+D + K E + N D +
Sbjct: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
Query: 365 YTLEKLLLVNASVQGPERVLTCMMEHEG 392
Y + + A G E+ TC +EH G
Sbjct: 172 Y---QGWITLAVPPGEEQRYTCQVEHPG 196
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 321 SCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQ 378
S + + C +YPQN+ + WL+D + K E + N D +Y + + A
Sbjct: 38 SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPP 94
Query: 379 GPERVLTCMMEHEG 392
G E+ TC +EH G
Sbjct: 95 GEEQRYTCQVEHPG 108
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 321 SCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQ 378
S + + C +YPQN+ + WL+D + K E + N D +Y + + A
Sbjct: 195 SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPP 251
Query: 379 GPERVLTCMMEHEG 392
G E+ TC +EH G
Sbjct: 252 GEEQRYTCQVEHPG 265
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 321 SCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQ 378
S + + C +YPQN+ + WL+D + K E + N D +Y + + A
Sbjct: 130 SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPP 186
Query: 379 GPERVLTCMMEHEG 392
G E+ TC +EH G
Sbjct: 187 GEEQRYTCQVEHPG 200
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 321 SCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQ 378
S + + C +YPQN+ + WL+D + K E + N D +Y + + A
Sbjct: 218 SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPP 274
Query: 379 GPERVLTCMMEHEG 392
G E+ TC +EH G
Sbjct: 275 GEEQRYTCQVEHPG 288
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 36.2 bits (82), Expect = 0.077
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 321 SCLVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQ 378
S + + C +YPQN+ + WL+D + K E + N D +Y + + A
Sbjct: 112 SKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPP 168
Query: 379 GPERVLTCMMEHEG 392
G E+ TC +EH G
Sbjct: 169 GEEQRYTCQVEHPG 182
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 323 LVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQGP 380
+ + C +YPQN+ + WL+D + K E + N D +Y + + A G
Sbjct: 118 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPPGE 174
Query: 381 ERVLTCMMEHEG 392
E+ TC +EH G
Sbjct: 175 EQRYTCQVEHPG 186
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 323 LVAVTCLVQRFYPQNVHLAWLEDCHTL--KGTEQPTLKKNNDRSYTLEKLLLVNASVQGP 380
+ + C +YPQN+ + WL+D + K E + N D +Y + + A G
Sbjct: 206 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY---QGWITLAVPPGE 262
Query: 381 ERVLTCMMEHEG 392
E+ TC +EH G
Sbjct: 263 EQRYTCQVEHPG 274
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 31/207 (14%)
Query: 74 SAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHR-----ALAEPLKTTMNLSQAT 128
SA L+P G + T VT+ +V++ I+C+V L P + T+
Sbjct: 34 SAAALIPTGDGQNLFTKD--VTVIEGEVAT-ISCQVNKSDDSVIQLLNPNRQTIYFRDFR 90
Query: 129 RNPDGTYSLEHTWQAEATL--------EEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
D + L + +E + +E + C + D PP ++ T+ V
Sbjct: 91 PLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD--PPQESYTTITVLV------ 142
Query: 181 QSVQPYKLQGPLQRSEP--GTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH 238
P L +Q+ G I + + S T+ W K EL ++ V+
Sbjct: 143 ---PPRNLMIDIQKDTAVEGEEIEVNCTAMA-SKPATTIRWFKGNTELKG-KSEVEEWSD 197
Query: 239 TYNVTSSVLVPLMDDDVFSHVVCHVEH 265
Y VTS +++ + +D V+C VEH
Sbjct: 198 MYTVTSQLMLKVHKEDDGVPVICQVEH 224
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 31/207 (14%)
Query: 74 SAQRLVPDNGGNDFITSKAWVTLTRQDVSSEITCEVTHR-----ALAEPLKTTMNLSQAT 128
SA L+P G + T VT+ +V++ I+C+V L P + T+
Sbjct: 34 SAAALIPTGDGQNLFTKD--VTVIEGEVAT-ISCQVNKSDDSVIQLLNPNRQTIYFRDFR 90
Query: 129 RNPDGTYSLEHTWQAEATL--------EEREFACWVVHDEQPPLKANVTLQAQVRRQGKG 180
D + L + +E + +E + C + D PP ++ T+ V
Sbjct: 91 PLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD--PPQESYTTITVLV------ 142
Query: 181 QSVQPYKLQGPLQRSEP--GTRIRLTYASSGFSTHQVTVTWLKNKHELPNPQTSVQYSGH 238
P L +Q+ G I + + S T+ W K EL ++ V+
Sbjct: 143 ---PPRNLMIDIQKDTAVEGEEIEVNCTAMA-SKPATTIRWFKGNTELKG-KSEVEEWSD 197
Query: 239 TYNVTSSVLVPLMDDDVFSHVVCHVEH 265
Y VTS +++ + +D V+C VEH
Sbjct: 198 MYTVTSQLMLKVHKEDDGVPVICQVEH 224
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,507,420
Number of Sequences: 37866
Number of extensions: 1119618
Number of successful extensions: 2967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 2800
Number of HSP's gapped (non-prelim): 173
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.