Guide to the Human Genome
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Search of human proteins with 116734696

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116734696 RNA binding motif protein 23 isoform 1 [Homo
sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]    869   0.0  
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]    826   0.0  
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]    776   0.0  
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]      474   e-134
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]     472   e-133
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...    95   1e-19
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...    95   1e-19
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...    92   7e-19
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...    84   3e-16
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s...    84   3e-16
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa...    83   4e-16
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    82   7e-16
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s...    82   1e-15
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor...    81   2e-15
gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo...    81   2e-15
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     80   3e-15
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    79   8e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    79   8e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    79   8e-15
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]              77   2e-14
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                     77   2e-14
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                77   3e-14
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      77   3e-14
gi|20373175 musashi 2 isoform a [Homo sapiens]                         77   4e-14
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     76   7e-14
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo...    76   7e-14
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      75   9e-14
gi|25121993 musashi 2 isoform b [Homo sapiens]                         75   2e-13
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    74   2e-13
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ...    74   2e-13

>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
          Length = 439

 Score =  869 bits (2246), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60
           MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK
Sbjct: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60

Query: 61  KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120
           KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
Sbjct: 61  KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120

Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180
           EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR
Sbjct: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180

Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240
           DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA
Sbjct: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
Sbjct: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360
           GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL
Sbjct: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360

Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420
           GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
Sbjct: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420

Query: 421 LNLASQCFQLSSLFTPQTM 439
           LNLASQCFQLSSLFTPQTM
Sbjct: 421 LNLASQCFQLSSLFTPQTM 439


>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
          Length = 423

 Score =  826 bits (2134), Expect = 0.0
 Identities = 422/439 (96%), Positives = 423/439 (96%), Gaps = 16/439 (3%)

Query: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60
           MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS 
Sbjct: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59

Query: 61  KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120
                          +RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
Sbjct: 60  ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104

Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180
           EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR
Sbjct: 105 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 164

Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240
           DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA
Sbjct: 165 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 224

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
Sbjct: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360
           GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL
Sbjct: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 344

Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420
           GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
Sbjct: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 404

Query: 421 LNLASQCFQLSSLFTPQTM 439
           LNLASQCFQLSSLFTPQTM
Sbjct: 405 LNLASQCFQLSSLFTPQTM 423


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score =  776 bits (2003), Expect = 0.0
 Identities = 404/439 (92%), Positives = 405/439 (92%), Gaps = 34/439 (7%)

Query: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60
           MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS 
Sbjct: 1   MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59

Query: 61  KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120
                          +RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
Sbjct: 60  ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104

Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180
           EDRVHYRSPPLATG                  EPVDNLSPEERDARTVFCMQLAARIRPR
Sbjct: 105 EDRVHYRSPPLATG------------------EPVDNLSPEERDARTVFCMQLAARIRPR 146

Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240
           DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA
Sbjct: 147 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 206

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
Sbjct: 207 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 266

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360
           GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL
Sbjct: 267 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 326

Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420
           GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
Sbjct: 327 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 386

Query: 421 LNLASQCFQLSSLFTPQTM 439
           LNLASQCFQLSSLFTPQTM
Sbjct: 387 LNLASQCFQLSSLFTPQTM 405


>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
          Length = 524

 Score =  474 bits (1220), Expect = e-134
 Identities = 274/465 (58%), Positives = 327/465 (70%), Gaps = 71/465 (15%)

Query: 7   DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66
           DI IEAMLEAPYKK+E++                S++N   E S         K+K+S+S
Sbjct: 4   DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40

Query: 67  HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126
            ++S +RKRS+S++R R R R  R +S  R+ R RSRS +RR  S SRSRD R   R  Y
Sbjct: 41  RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95

Query: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168
           RSP                   +    R   SKSP  ++KSPVREP+DNL+PEERDARTV
Sbjct: 96  RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155

Query: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228
           FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG
Sbjct: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215

Query: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288
           QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+
Sbjct: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275

Query: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348
           I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D  + 
Sbjct: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335

Query: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404
            +F D D+     +DLG+  GR QLMA+LAEG G+Q+P  A           ALQ++G++
Sbjct: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385

Query: 405 PLGAL-----------NPAALTALSPALNLASQCFQLSSLFTPQT 438
             GA+             +AL A +    LA+QCFQLS++F PQT
Sbjct: 386 AFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 430


>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
          Length = 530

 Score =  472 bits (1214), Expect = e-133
 Identities = 274/471 (58%), Positives = 327/471 (69%), Gaps = 77/471 (16%)

Query: 7   DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66
           DI IEAMLEAPYKK+E++                S++N   E S         K+K+S+S
Sbjct: 4   DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40

Query: 67  HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126
            ++S +RKRS+S++R R R R  R +S  R+ R RSRS +RR  S SRSRD R   R  Y
Sbjct: 41  RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95

Query: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168
           RSP                   +    R   SKSP  ++KSPVREP+DNL+PEERDARTV
Sbjct: 96  RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155

Query: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228
           FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG
Sbjct: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215

Query: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288
           QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+
Sbjct: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275

Query: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348
           I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D  + 
Sbjct: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335

Query: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404
            +F D D+     +DLG+  GR QLMA+LAEG G+Q+P  A           ALQ++G++
Sbjct: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385

Query: 405 PLGAL-----------------NPAALTALSPALNLASQCFQLSSLFTPQT 438
             GA+                   +AL A +    LA+QCFQLS++F PQT
Sbjct: 386 AFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)

Query: 154 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 209
           P+ +++ + + A  + C      I     ED     F+  G ++ + +  D  + + KG 
Sbjct: 70  PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129

Query: 210 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 269
           A+VE+   ++  LA+      +LG   I     +   +   + + L +      R+YV S
Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189

Query: 270 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 329
           +H ++++D ++ +FE FGKI +  L +D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249

Query: 330 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 389
            G+ +RVG           +T P                 M  L       LP  AA AA
Sbjct: 250 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 283

Query: 390 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 424
           AAA      Q  + GA  LG L    L  +SPAL LA
Sbjct: 284 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 318


>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)

Query: 154 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 209
           P+ +++ + + A  + C      I     ED     F+  G ++ + +  D  + + KG 
Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172

Query: 210 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 269
           A+VE+   ++  LA+      +LG   I     +   +   + + L +      R+YV S
Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232

Query: 270 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 329
           +H ++++D ++ +FE FGKI +  L +D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292

Query: 330 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 389
            G+ +RVG           +T P                 M  L       LP  AA AA
Sbjct: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326

Query: 390 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 424
           AAA      Q  + GA  LG L    L  +SPAL LA
Sbjct: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%)

Query: 186 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 245
           F+  G ++ + +  D  + + KG A+VE+   ++  LA+      +LG   I     +  
Sbjct: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191

Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305
            +   + + L +      R+YV S+H ++++D ++ +FE FGKI +  L +D  TG+ KG
Sbjct: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 365
           YGFI +  ++ ++ A+  +N F+L G+ +RVG           +T P             
Sbjct: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289

Query: 366 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 423
               M  L       LP  AA AAAAA      Q  + GA  LG L    L  +SPAL L
Sbjct: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343

Query: 424 A 424
           A
Sbjct: 344 A 344



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 37/98 (37%), Positives = 56/98 (57%)

Query: 240 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 299
           A Q ++     MA   Q+      R+YVGS+++ + ED +R  F PFG I +I +  DS 
Sbjct: 89  AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148

Query: 300 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 337
           T + KG+ F+ +   E A+ ALEQ+N   L GR ++VG
Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 15/65 (23%), Positives = 32/65 (49%)

Query: 155 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 214
           +D L+ E R    ++   +   +   D++  F A GK++   +  D  + + KG  ++E+
Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257

Query: 215 CEIQS 219
            + QS
Sbjct: 258 EKAQS 262


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 86/332 (25%), Positives = 139/332 (41%), Gaps = 83/332 (25%)

Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75

Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNR 247
             GK+ ++ ++ DR +   KG A++ +CE +S   A               Q++  E+  
Sbjct: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKA---------------QSALHEQKT 120

Query: 248 LAAMANNLQ------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTG 301
           L  M   +Q      +  G   +L+VG L+   +ED +R +FE FG I+   +++  D G
Sbjct: 121 LPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-G 179

Query: 302 RSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE- 357
            SKG  F+ +S    A+ A+  L+G             ++ + G +    + F D D+E 
Sbjct: 180 NSKGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKER 226

Query: 358 -------------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAA 390
                              +  G+ G   Q        LMA +A+G    L   AA AAA
Sbjct: 227 TMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAA 284

Query: 391 AAAQAAALQLNG--AVPL----GALNPAALTA 416
              Q AAL +NG  A P+    G   P  +TA
Sbjct: 285 QMQQMAALNMNGLAAAPMTPTSGGSTPPGITA 316


>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 485

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 85/327 (25%), Positives = 142/327 (43%), Gaps = 64/327 (19%)

Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75

Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 245
             GK+ ++ ++ DR +   KG A++ +CE +S   A     ++  L G+   +Q   A+ 
Sbjct: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135

Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305
                 ++ L++      +L+VG L+   +ED +R +FE FG I+   +++  D G SKG
Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 357
             F+ +S    A+ A+  L+G             ++ + G +    + F D D+E     
Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240

Query: 358 ---------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAAQA 395
                          +  G+ G   Q       LMA +A+G    L   AA AAA   Q 
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQQM 298

Query: 396 AALQLNG--AVPL----GALNPAALTA 416
           AAL +NG  A P+    G   P  +TA
Sbjct: 299 AALNMNGLAAAPMTPTSGGSTPPGITA 325



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 9/31 (29%), Positives = 22/31 (70%)

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336
           +GF++F +   A+ A++ +NGF++  + ++V
Sbjct: 443 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 473


>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%)

Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75

Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 245
             GK+ ++ ++ DR +   KG A++ +CE +S   A     ++  L G+   +Q   A+ 
Sbjct: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135

Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305
                 ++ L++      +L+VG L+   +ED +R +FE FG I+   +++  D G SKG
Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 357
             F+ +S    A+ A+  L+G             ++ + G +    + F D D+E     
Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240

Query: 358 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 394
                          +  G+ G   Q        LMA +A+G    L   AA AAA   Q
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298

Query: 395 AAALQLNG--AVPL----GALNPAALTA 416
            AAL +NG  A P+    G   P  +TA
Sbjct: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 9/31 (29%), Positives = 22/31 (70%)

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336
           +GF++F +   A+ A++ +NGF++  + ++V
Sbjct: 444 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 474


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 51/178 (28%), Positives = 99/178 (55%), Gaps = 8/178 (4%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 226
           VF   L   I  + L + FSA GK+   +++SD   + SKG A+V F    +   AI  +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157

Query: 227 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 286
            G+ L G  + V   +  K+R A + +   +       +Y+ +   ++ ++ L+ +F  +
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTN----VYIKNFGGDMDDERLKDVFSKY 213

Query: 287 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344
           GK  ++ +M DS +G+SKG+GF++F   E A++A+E++NG ++ G+ + VG   ++++
Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 12/163 (7%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L+D FS  GK   V++++D +S +SKG  +V F   ++   A+  + G+ + G  I V  
Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264

Query: 241 SQAEKNRLAAMANNLQ-------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIV 293
           +Q +  R A +    +       +G  G ++LY+ +L   I ++ LR  F  FG I  + 
Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323

Query: 294 LMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336
           +M++   G+SKG+G I FS  E A +A+ ++NG  L  +P+ +
Sbjct: 324 VMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364



 Score = 65.9 bits (159), Expect = 7e-11
 Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 11/159 (6%)

Query: 186 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 245
           FS VG V  +RI  D+ +RRS G AYV F ++     A+      ++         + + 
Sbjct: 30  FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDII---------KGKS 80

Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305
            RL     +      G   +++ +L  +I    L   F  FGKI +  +M D D G SKG
Sbjct: 81  IRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD-DQG-SKG 138

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344
           Y F+ F +   A RA+E++NG  L G  + VG    R D
Sbjct: 139 YAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 26/72 (36%), Positives = 43/72 (59%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TED+L   F   G + +I + +D  T RS GY ++ F     A++AL+ +
Sbjct: 12  LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71

Query: 325 NGFELAGRPMRV 336
           N   + G+ +R+
Sbjct: 72  NFDIIKGKSIRL 83


>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
           sapiens]
          Length = 484

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 87/329 (26%), Positives = 142/329 (43%), Gaps = 69/329 (20%)

Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75

Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLA-IGLTGQRLL---GVPIIVQASQA 243
             GK+ ++ ++ DR +   KG A++ +CE +S   A   L  Q+ L     PI V+ + +
Sbjct: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135

Query: 244 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 303
           E        ++  +      +L+VG L+   +ED +R +FE FG I+   +++  D G S
Sbjct: 136 ESRG----GSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNS 190

Query: 304 KGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE--- 357
           KG  F+ +S    A+ A+  L+G             ++ + G +    + F D D+E   
Sbjct: 191 KGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTM 237

Query: 358 -----------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAA 393
                            +  G+ G   Q       LMA +A+G    L   AA AAA   
Sbjct: 238 RRMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQ 295

Query: 394 QAAALQLNG--AVPL----GALNPAALTA 416
           Q AAL +NG  A P+    G   P  +TA
Sbjct: 296 QMAALNMNGLAAAPMTPTSGGSTPPGITA 324



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 9/31 (29%), Positives = 22/31 (70%)

Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336
           +GF++F +   A+ A++ +NGF++  + ++V
Sbjct: 442 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 472


>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
           [Homo sapiens]
          Length = 475

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 88/337 (26%), Positives = 141/337 (41%), Gaps = 50/337 (14%)

Query: 57  ETSKKKRSRSHNKSRDRKR-SRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRS 115
           E   +KRS S ++SRDRKR SRSRDR R R + S SR   R+ +  +R     HG   RS
Sbjct: 21  ENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRS 79

Query: 116 RDHRREDRV--HYRSPPLA----TGYRYGHSKS--------------PHFREKSPVREPV 155
             H ++ +V  ++  PP      T  +Y   ++              P     +P   PV
Sbjct: 80  PRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPV 139

Query: 156 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSR 204
              S   R AR ++   +   I    + DFF+A  +           V  V+I  D+N  
Sbjct: 140 VG-SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-- 196

Query: 205 RSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM- 263
                A++EF  +     A+   G    G  + ++    +   L  M+ N      G + 
Sbjct: 197 ----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVS 251

Query: 264 --------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315
                   +L++G L   + +D ++ +   FG +    L+KDS TG SKGY F  + D  
Sbjct: 252 TVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDIN 311

Query: 316 CARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFP 352
              +A+  LNG +L  + + V   +      T ++ P
Sbjct: 312 VTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPP 348


>gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform
           b [Homo sapiens]
          Length = 471

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 86/321 (26%), Positives = 136/321 (42%), Gaps = 50/321 (15%)

Query: 57  ETSKKKRSRSHNKSRDRKR-SRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRS 115
           E   +KRS S ++SRDRKR SRSRDR R R + S SR   R+ +  +R     HG   RS
Sbjct: 21  ENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRS 79

Query: 116 RDHRREDRV--HYRSPPLA----TGYRYGHSKS--------------PHFREKSPVREPV 155
             H ++ +V  ++  PP      T  +Y   ++              P     +P   PV
Sbjct: 80  PRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPV 139

Query: 156 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSR 204
              S   R AR ++   +   I    + DFF+A  +           V  V+I  D+N  
Sbjct: 140 VG-SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-- 196

Query: 205 RSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM- 263
                A++EF  +     A+   G    G  + ++    +   L  M+ N      G + 
Sbjct: 197 ----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVS 251

Query: 264 --------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315
                   +L++G L   + +D ++ +   FG +    L+KDS TG SKGY F  + D  
Sbjct: 252 TVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDIN 311

Query: 316 CARRALEQLNGFELAGRPMRV 336
              +A+  LNG +L  + + V
Sbjct: 312 VTDQAIAGLNGMQLGDKKLLV 332


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 66/189 (34%), Positives = 88/189 (46%), Gaps = 33/189 (17%)

Query: 31  KKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRS-----RSHNKSRDRKRSRSRDRDRYR 85
           +++Y    + S S SG+      +   T  + RS     RS +KSR R  SRSR R   R
Sbjct: 6   EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65

Query: 86  RRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHF 145
           R  +RSRS       RSRS  RR  S S SRD+RR               R+ HS SP  
Sbjct: 66  RHYTRSRS-------RSRS-HRRSRSRSYSRDYRR---------------RHSHSHSPMS 102

Query: 146 REKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRR 205
             +   R   +  +P+      VF + L      RDL + FS  G + DV I+ D+ SRR
Sbjct: 103 TRR---RHVGNRANPDPNCCLGVFGLSLYT--TERDLREVFSKYGPIADVSIVYDQQSRR 157

Query: 206 SKGIAYVEF 214
           S+G A+V F
Sbjct: 158 SRGFAFVYF 166



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 27/72 (37%), Positives = 42/72 (58%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           L V  L    TE  LR +F  +G I ++ ++ D  + RS+G+ F+ F + + A+ A E+ 
Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179

Query: 325 NGFELAGRPMRV 336
           NG EL GR +RV
Sbjct: 180 NGMELDGRRIRV 191


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)

Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179
           GY Y + + P   E++            P+R       P  R +    VF   L   I  
Sbjct: 53  GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112

Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238
           + L D FSA G +   +++ D N   SKG A+V F   ++   AI  + G  L    + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298
              ++ K R A +    ++       +Y+ +    + ++ L+ +F  FGK  ++ +M+D 
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226

Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344
           + G+SKG+GF+++   E A +A+E++NG E++G+ + VG   ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)

Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211
           +E    L  + ++   V+       +    L++ FS  GK   V+++ D N + SKG  +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235

Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264
           V + + +    A+  + G+ + G  I V  +Q +  R A +    ++           + 
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LY+ +L   I ++ LR  F PFG I +  +M +   GRSKG+GF+ FS  E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 325 NGFELAGRPMRV 336
           NG  +  +P+ V
Sbjct: 354 NGRIVGSKPLYV 365



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L + FS  G V  +R+  D  +RRS G AYV F +      A+  +    + G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I +  ++   D 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342
             SKGY F+ F   E A +A+E++NG  L  R + VG    R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 29/72 (40%), Positives = 43/72 (59%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TE ML   F P G + +I + +D  T RS GY ++ F     A RAL+ +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 325 NGFELAGRPMRV 336
           N   + G+P+R+
Sbjct: 73  NFDVIKGKPIRI 84


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)

Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179
           GY Y + + P   E++            P+R       P  R +    VF   L   I  
Sbjct: 53  GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112

Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238
           + L D FSA G +   +++ D N   SKG A+V F   ++   AI  + G  L    + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298
              ++ K R A +    ++       +Y+ +    + ++ L+ +F  FGK  ++ +M+D 
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226

Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344
           + G+SKG+GF+++   E A +A+E++NG E++G+ + VG   ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)

Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211
           +E    L  + ++   V+       +    L++ FS  GK   V+++ D N + SKG  +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235

Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264
           V + + +    A+  + G+ + G  I V  +Q +  R A +    ++           + 
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LY+ +L   I ++ LR  F PFG I +  +M +   GRSKG+GF+ FS  E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 325 NGFELAGRPMRV 336
           NG  +  +P+ V
Sbjct: 354 NGRIVGSKPLYV 365



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L + FS  G V  +R+  D  +RRS G AYV F +      A+  +    + G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I +  ++   D 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342
             SKGY F+ F   E A +A+E++NG  L  R + VG    R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 29/72 (40%), Positives = 43/72 (59%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TE ML   F P G + +I + +D  T RS GY ++ F     A RAL+ +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 325 NGFELAGRPMRV 336
           N   + G+P+R+
Sbjct: 73  NFDVIKGKPIRI 84


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)

Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179
           GY Y + + P   E++            P+R       P  R +    VF   L   I  
Sbjct: 53  GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112

Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238
           + L D FSA G +   +++ D N   SKG A+V F   ++   AI  + G  L    + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298
              ++ K R A +    ++       +Y+ +    + ++ L+ +F  FGK  ++ +M+D 
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226

Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344
           + G+SKG+GF+++   E A +A+E++NG E++G+ + VG   ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)

Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211
           +E    L  + ++   V+       +    L++ FS  GK   V+++ D N + SKG  +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235

Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264
           V + + +    A+  + G+ + G  I V  +Q +  R A +    ++           + 
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LY+ +L   I ++ LR  F PFG I +  +M +   GRSKG+GF+ FS  E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 325 NGFELAGRPMRV 336
           NG  +  +P+ V
Sbjct: 354 NGRIVGSKPLYV 365



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L + FS  G V  +R+  D  +RRS G AYV F +      A+  +    + G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I +  ++   D 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342
             SKGY F+ F   E A +A+E++NG  L  R + VG    R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 29/72 (40%), Positives = 43/72 (59%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TE ML   F P G + +I + +D  T RS GY ++ F     A RAL+ +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 325 NGFELAGRPMRV 336
           N   + G+P+R+
Sbjct: 73  NFDVIKGKPIRI 84


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 11/183 (6%)

Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220
           ++   RT++   L+  +    +   FS +G  +  ++I++  S  +    +VEF E +  
Sbjct: 4   DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61

Query: 221 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 279
             A+  + G+++LG  +        K   A   ++ +K       ++VG L   IT + +
Sbjct: 62  AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113

Query: 280 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 339
           +  F PFGKI +  ++KD  TG+SKGYGF++F +   A  A+  + G  L GR +R    
Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173

Query: 340 TER 342
           T +
Sbjct: 174 TRK 176



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 23/182 (12%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227
           VF   L+  I   D++  F+  GK+ D R++ D  + +SKG  +V F        AI   
Sbjct: 99  VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158

Query: 228 GQRLLG--------------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFN 273
           G + LG               P   Q +  ++ R   + N     N     +Y G +   
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKN---CTVYCGGIASG 215

Query: 274 ITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 333
           +T+ ++R  F PFG+I  I +  +      KGY F+ FS  E A  A+  +NG  + G  
Sbjct: 216 LTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHV 269

Query: 334 MR 335
           ++
Sbjct: 270 VK 271



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 255 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 314
           + + +G P  LYVG+L  ++TE ++  +F   G   +  ++ +  +  +  Y F+ F + 
Sbjct: 1   MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEH 58

Query: 315 ECARRALEQLNGFELAGRPMRVGHVT 340
             A  AL  +NG ++ G+ ++V   T
Sbjct: 59  RDAAAALAAMNGRKILGKEVKVNWAT 84



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 15/98 (15%)

Query: 127 RSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFF 186
           R PP     +  ++K   F +       V+  SP+     TV+C  +A+ +  + +   F
Sbjct: 175 RKPPAPKSTQENNTKQLRFEDV------VNQSSPKNC---TVYCGGIASGLTDQLMRQTF 225

Query: 187 SAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAI 224
           S  G++ ++R+  +      KG ++V F   +S   AI
Sbjct: 226 SPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAI 257


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 11/183 (6%)

Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220
           E+   +T++   L+  +    +   FS +G  ++ ++I D  +  +    +VEF E +  
Sbjct: 2   EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59

Query: 221 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 279
             A+  + G++++G  +        K   A   ++ +K       ++VG L   IT + +
Sbjct: 60  AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111

Query: 280 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 339
           +  F PFG+I +  ++KD  TG+SKGYGF++F +   A  A++Q+ G  L GR +R    
Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171

Query: 340 TER 342
           T +
Sbjct: 172 TRK 174



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227
           VF   L+  I   D++  F+  G++ D R++ D  + +SKG  +V F        AI   
Sbjct: 97  VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156

Query: 228 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276
           G + LG            P   +++     +  +    + + +     +Y G +   +TE
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216

Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336
            ++R  F PFG+I  I +  D      KGY F+ F+  E A  A+  +NG  + G  ++ 
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 270

Query: 337 GHVTERLD 344
               E LD
Sbjct: 271 YWGKETLD 278


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 14/187 (7%)

Query: 158 LSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEI 217
           +S   +DA TV+   L  ++    L + F   G V +  +  DR + + +G  +VEF   
Sbjct: 6   ISERNQDA-TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64

Query: 218 QSVPLAIGLTGQ-RLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276
           +    AI +    +L G PI V  + A    L   AN           +++G+L   I E
Sbjct: 65  EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGAN-----------IFIGNLDPEIDE 113

Query: 277 DMLRGIFEPFGKI-DNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 335
            +L   F  FG I     +M+D DTG SKGY FI F+  + +  A+E +NG  L  RP+ 
Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173

Query: 336 VGHVTER 342
           V +  ++
Sbjct: 174 VSYAFKK 180



 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 34/98 (34%), Positives = 55/98 (56%), Gaps = 3/98 (3%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           +YVG L   ++E +L  +F   G + N  + KD  TG+ +GYGF+ F   E A  A++ +
Sbjct: 15  VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74

Query: 325 NGFELAGRPMRVGHVT---ERLDGGTDITFPDGDQELD 359
           N  +L G+P+RV   +   + LD G +I   + D E+D
Sbjct: 75  NMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEID 112


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 59/231 (25%), Positives = 112/231 (48%), Gaps = 22/231 (9%)

Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179
           GY Y + + P   E++            PVR       P  R +    +F   L   I  
Sbjct: 53  GYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDN 112

Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238
           + L D FSA G +   +++ D N   SKG  +V F   ++   AI  + G  L    + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170

Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298
              ++ K R A +    ++       +Y+ +   ++ ++ L+ +F  FG   ++ +M D 
Sbjct: 171 GRFKSRKEREAELGARAKEFTN----VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD- 225

Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDI 349
           ++G+SKG+GF++F   E A++A++++NG EL G+ + VG   ++++  T++
Sbjct: 226 ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL 276



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%)

Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211
           +E    L    ++   V+       +    L+D F   G    V++++D  S +SKG  +
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235

Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 264
           V F   +    A+  + G+ L G  I V  +Q +  R   +    ++     +       
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN 295

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYV +L   I ++ LR  F PFG I +  +M +   GRSKG+GF+ FS  E A +A+ ++
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 325 NGFELAGRPMRV 336
           NG  +A +P+ V
Sbjct: 354 NGRIVATKPLYV 365



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 13/162 (8%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L + FS  G +  +R+  D  +RRS G AYV F +      A+  +    + G P+ +  
Sbjct: 27  LYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMW 86

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I +  ++   D 
Sbjct: 87  SQRDP--------SLRKSGVG--NIFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134

Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342
             SKGYGF+ F   E A RA+E++NG  L  R + VG    R
Sbjct: 135 NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 30/72 (41%), Positives = 43/72 (59%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TE ML   F P G I +I + +D  T RS GY ++ F     A RAL+ +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 325 NGFELAGRPMRV 336
           N   + G+P+R+
Sbjct: 73  NFDVIKGKPVRI 84


>gi|20373175 musashi 2 isoform a [Homo sapiens]
          Length = 328

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 64/263 (24%), Positives = 114/263 (43%), Gaps = 23/263 (8%)

Query: 162 ERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVP 221
           + D   +F   L+ +  P  L D+FS  G++R+  ++ D  ++RS+G  +V F +  SV 
Sbjct: 17  QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75

Query: 222 LAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRG 281
                   ++LG P     S+    ++A       K      +++VG L  N   + ++ 
Sbjct: 76  -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128

Query: 282 IFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTE 341
            FE FGK+++ +LM D  T R +G+GF+TF + +   +  E ++  E+  + +       
Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE-IHFHEINNKMVECKKAQP 187

Query: 342 RLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGI----QLPSTAAAAAAAAAQAAA 397
           +     ++ FP G +    G A G    M     G G+       +T        A +  
Sbjct: 188 K-----EVMFPPGTR----GRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYG 238

Query: 398 LQLNGAVPLGALNPAALTALSPA 420
            Q  G  P  A  P A  A++ A
Sbjct: 239 YQFPG-FPAAAYGPVAAAAVAAA 260



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 25/80 (31%), Positives = 42/80 (52%)

Query: 244 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 303
           E N     + +       P ++++G L +  + D LR  F  FG+I   ++M+D  T RS
Sbjct: 2   EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61

Query: 304 KGYGFITFSDSECARRALEQ 323
           +G+GF+TF+D     + L Q
Sbjct: 62  RGFGFVTFADPASVDKVLGQ 81


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 8/187 (4%)

Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220
           E+   +T++   L+  +    +   FS +G  ++ ++I D  +  +    +VEF E +  
Sbjct: 2   EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59

Query: 221 PLAIG-LTGQRLLGVPIIVQ----ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNIT 275
             A+  + G++++G  + V      S  +K+  ++   + Q+       ++VG L   IT
Sbjct: 60  AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDH-FHVFVGDLSPEIT 118

Query: 276 EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 335
            + ++  F PFG+I +  ++KD  TG+SKGYGF++F +   A  A++Q+ G  L GR +R
Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178

Query: 336 VGHVTER 342
               T +
Sbjct: 179 TNWATRK 185



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227
           VF   L+  I   D++  F+  G++ D R++ D  + +SKG  +V F        AI   
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167

Query: 228 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276
           G + LG            P   +++     +  +    + + +     +Y G +   +TE
Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227

Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336
            ++R  F PFG+I  I +  D      KGY F+ F+  E A  A+  +NG  + G  ++ 
Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 281

Query: 337 GHVTERLD 344
               E LD
Sbjct: 282 YWGKETLD 289


>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
           sapiens]
          Length = 420

 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 70/262 (26%), Positives = 114/262 (43%), Gaps = 32/262 (12%)

Query: 76  SRSRDRDRYRRRNSRSRSPGRQC--------RHRSRSWDRRHGSES---RSRDHRREDRV 124
           S +R   R  +R+  ++ P R          R R     RRH   S   RS       R 
Sbjct: 48  SSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRT 107

Query: 125 HYRSPPLATGYRYG----HSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180
             + PP  +         +S    F E S +     N S  ++D   +F   L+     +
Sbjct: 108 ARQHPPADSSVTMEDMNEYSNIEEFAEGSKI-----NASKNQQDDGKMFIGGLSWDTSKK 162

Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240
           DL ++ S  G+V D  I +D  + RS+G  +V F +  SV   + L   +L G  I  + 
Sbjct: 163 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR 222

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
           ++A             KG   P +++VG L  + +E+ ++  F  FG+I+NI L  D+ T
Sbjct: 223 AKA------------LKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKT 270

Query: 301 GRSKGYGFITFSDSECARRALE 322
              +G+ FIT++D E  ++ LE
Sbjct: 271 NERRGFCFITYTDEEPVKKLLE 292


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 75.5 bits (184), Expect = 9e-14
 Identities = 49/183 (26%), Positives = 96/183 (52%), Gaps = 8/183 (4%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 226
           +F   L   I  + L D  SA G +    ++ D N   SKG  +V F   ++   AI  +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158

Query: 227 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 286
            G  L G  + V   ++ K R A +    ++       +Y+ +   ++ ++ L+ +F  F
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPN----VYIKNFGEDMDDERLKDLFGKF 214

Query: 287 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGG 346
           G   ++ +M D ++G+SKG+GF++F   E A++A++++NG EL G+ + VG   ++++  
Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273

Query: 347 TDI 349
           T++
Sbjct: 274 TEL 276



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%)

Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211
           +E    L    ++   V+       +    L+D F   G    V++++D  S +SKG  +
Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235

Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 264
           V F   +    A+  + G+ L G  I V  +Q +  R   +    ++     +       
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 295

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYV +L   I ++ LR  F PFG I +  +M +   GRSKG+GF+ FS  E A +A+ ++
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 325 NGFELAGRPMRV 336
           NG  +A +P+ V
Sbjct: 354 NGRIVATKPLYV 365



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 17/164 (10%)

Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240
           L + FS  G +  +RI  D  +  S   AYV F   +    A+  +    + G P+ +  
Sbjct: 27  LYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMW 86

Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKI--DNIVLMKDS 298
           SQ +         +L+K   G   ++V +L  +I    L      FG I   N+V     
Sbjct: 87  SQRDP--------SLRKSGVG--NIFVKNLDKSINNKALYDTVSAFGNILSCNVV----C 132

Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342
           D   SKGYGF+ F   E A RA++++NG  L GR + VG    R
Sbjct: 133 DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSR 176



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 27/72 (37%), Positives = 42/72 (58%)

Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324
           LYVG LH ++TE ML   F P G I +I + +D  T  S  Y ++ F  ++ A  AL+ +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72

Query: 325 NGFELAGRPMRV 336
           N   + G+P+R+
Sbjct: 73  NFDVIKGKPVRI 84


>gi|25121993 musashi 2 isoform b [Homo sapiens]
          Length = 251

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 8/155 (5%)

Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227
           +F   L+ +  P  L D+FS  G++R+  ++ D  ++RS+G  +V F +  SV       
Sbjct: 19  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71

Query: 228 GQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFG 287
             ++LG P     S+    ++A       K      +++VG L  N   + ++  FE FG
Sbjct: 72  -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130

Query: 288 KIDNIVLMKDSDTGRSKGYGFITFSDSECARRALE 322
           K+++ +LM D  T R +G+GF+TF + +   +  E
Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 22/60 (36%), Positives = 37/60 (61%)

Query: 264 RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 323
           ++++G L +  + D LR  F  FG+I   ++M+D  T RS+G+GF+TF+D     + L Q
Sbjct: 18  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 8/170 (4%)

Query: 147 EKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRS 206
           EK+    P++    E+   R +F   L+       L +++   GK+ D  ++ D  S+RS
Sbjct: 2   EKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS 61

Query: 207 KGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMR-L 265
           +G  +V F  +  V  A+          P  +     E  R  A   + + G    ++ L
Sbjct: 62  RGFGFVTFSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKL 114

Query: 266 YVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315
           +VG +  +  E  LR  FE +GKID I ++ D  +G+ +G+GF+TF D +
Sbjct: 115 FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD 164


>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
           [Homo sapiens]
          Length = 285

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 157 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 216
           N S  E DA  +F   L+     +DL+D+F+  G+V D  I  D N+ RS+G  ++ F +
Sbjct: 61  NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120

Query: 217 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276
             SV   +     RL G  I       +  +  AM  +  K      +++VG L+   TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167

Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 323
           + +R  F  FG+I+ I L  D    + +G+ FITF + E  ++ LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,470,709
Number of Sequences: 37866
Number of extensions: 776501
Number of successful extensions: 12468
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 457
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 5546
Number of HSP's gapped (non-prelim): 3128
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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