BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] (439 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 869 0.0 gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 826 0.0 gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 776 0.0 gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 474 e-134 gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 472 e-133 gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 95 1e-19 gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 95 1e-19 gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 92 7e-19 gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 84 3e-16 gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 84 3e-16 gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 83 4e-16 gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 82 7e-16 gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 82 1e-15 gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 81 2e-15 gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo... 81 2e-15 gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 80 3e-15 gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 79 8e-15 gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 79 8e-15 gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 79 8e-15 gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 77 2e-14 gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 77 2e-14 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 77 3e-14 gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 77 3e-14 gi|20373175 musashi 2 isoform a [Homo sapiens] 77 4e-14 gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 76 7e-14 gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 76 7e-14 gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 75 9e-14 gi|25121993 musashi 2 isoform b [Homo sapiens] 75 2e-13 gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 74 2e-13 gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 74 2e-13 >gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] Length = 439 Score = 869 bits (2246), Expect = 0.0 Identities = 439/439 (100%), Positives = 439/439 (100%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60 Query: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR Sbjct: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120 Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR Sbjct: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA Sbjct: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT Sbjct: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL Sbjct: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360 Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA Sbjct: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420 Query: 421 LNLASQCFQLSSLFTPQTM 439 LNLASQCFQLSSLFTPQTM Sbjct: 421 LNLASQCFQLSSLFTPQTM 439 >gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] Length = 423 Score = 826 bits (2134), Expect = 0.0 Identities = 422/439 (96%), Positives = 423/439 (96%), Gaps = 16/439 (3%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59 Query: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120 +RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR Sbjct: 60 ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104 Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR Sbjct: 105 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 164 Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA Sbjct: 165 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 224 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT Sbjct: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL Sbjct: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 344 Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA Sbjct: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 404 Query: 421 LNLASQCFQLSSLFTPQTM 439 LNLASQCFQLSSLFTPQTM Sbjct: 405 LNLASQCFQLSSLFTPQTM 423 >gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] Length = 405 Score = 776 bits (2003), Expect = 0.0 Identities = 404/439 (92%), Positives = 405/439 (92%), Gaps = 34/439 (7%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59 Query: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120 +RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR Sbjct: 60 ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104 Query: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 EDRVHYRSPPLATG EPVDNLSPEERDARTVFCMQLAARIRPR Sbjct: 105 EDRVHYRSPPLATG------------------EPVDNLSPEERDARTVFCMQLAARIRPR 146 Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA Sbjct: 147 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 206 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT Sbjct: 207 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 266 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL Sbjct: 267 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 326 Query: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA Sbjct: 327 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 386 Query: 421 LNLASQCFQLSSLFTPQTM 439 LNLASQCFQLSSLFTPQTM Sbjct: 387 LNLASQCFQLSSLFTPQTM 405 >gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] Length = 524 Score = 474 bits (1220), Expect = e-134 Identities = 274/465 (58%), Positives = 327/465 (70%), Gaps = 71/465 (15%) Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66 DI IEAMLEAPYKK+E++ S++N E S K+K+S+S Sbjct: 4 DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40 Query: 67 HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126 ++S +RKRS+S++R R R R R +S R+ R RSRS +RR S SRSRD R R Y Sbjct: 41 RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95 Query: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168 RSP + R SKSP ++KSPVREP+DNL+PEERDARTV Sbjct: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155 Query: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228 FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG Sbjct: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215 Query: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288 QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+ Sbjct: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275 Query: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348 I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + Sbjct: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335 Query: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404 +F D D+ +DLG+ GR QLMA+LAEG G+Q+P A ALQ++G++ Sbjct: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385 Query: 405 PLGAL-----------NPAALTALSPALNLASQCFQLSSLFTPQT 438 GA+ +AL A + LA+QCFQLS++F PQT Sbjct: 386 AFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 430 >gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] Length = 530 Score = 472 bits (1214), Expect = e-133 Identities = 274/471 (58%), Positives = 327/471 (69%), Gaps = 77/471 (16%) Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66 DI IEAMLEAPYKK+E++ S++N E S K+K+S+S Sbjct: 4 DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40 Query: 67 HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126 ++S +RKRS+S++R R R R R +S R+ R RSRS +RR S SRSRD R R Y Sbjct: 41 RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95 Query: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168 RSP + R SKSP ++KSPVREP+DNL+PEERDARTV Sbjct: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155 Query: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228 FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG Sbjct: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215 Query: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288 QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+ Sbjct: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275 Query: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348 I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + Sbjct: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335 Query: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404 +F D D+ +DLG+ GR QLMA+LAEG G+Q+P A ALQ++G++ Sbjct: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385 Query: 405 PLGAL-----------------NPAALTALSPALNLASQCFQLSSLFTPQT 438 GA+ +AL A + LA+QCFQLS++F PQT Sbjct: 386 AFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436 >gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo sapiens] Length = 516 Score = 94.7 bits (234), Expect = 1e-19 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%) Query: 154 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 209 P+ +++ + + A + C I ED F+ G ++ + + D + + KG Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129 Query: 210 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 269 A+VE+ ++ LA+ +LG I + + + + L + R+YV S Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189 Query: 270 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 329 +H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249 Query: 330 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 389 G+ +RVG +T P M L LP AA AA Sbjct: 250 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 283 Query: 390 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 424 AAA Q + GA LG L L +SPAL LA Sbjct: 284 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 318 >gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo sapiens] Length = 559 Score = 94.7 bits (234), Expect = 1e-19 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%) Query: 154 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 209 P+ +++ + + A + C I ED F+ G ++ + + D + + KG Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172 Query: 210 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 269 A+VE+ ++ LA+ +LG I + + + + L + R+YV S Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232 Query: 270 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 329 +H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292 Query: 330 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 389 G+ +RVG +T P M L LP AA AA Sbjct: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326 Query: 390 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 424 AAA Q + GA LG L L +SPAL LA Sbjct: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361 >gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo sapiens] Length = 542 Score = 92.4 bits (228), Expect = 7e-19 Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%) Query: 186 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 245 F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I + Sbjct: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191 Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305 + + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG Sbjct: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251 Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 365 YGFI + ++ ++ A+ +N F+L G+ +RVG +T P Sbjct: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289 Query: 366 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 423 M L LP AA AAAAA Q + GA LG L L +SPAL L Sbjct: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343 Query: 424 A 424 A Sbjct: 344 A 344 Score = 68.2 bits (165), Expect = 1e-11 Identities = 37/98 (37%), Positives = 56/98 (57%) Query: 240 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 299 A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS Sbjct: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148 Query: 300 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 337 T + KG+ F+ + E A+ ALEQ+N L GR ++VG Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186 Score = 35.0 bits (79), Expect = 0.14 Identities = 15/65 (23%), Positives = 32/65 (49%) Query: 155 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 214 +D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+ Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257 Query: 215 CEIQS 219 + QS Sbjct: 258 EKAQS 262 >gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo sapiens] Length = 448 Score = 83.6 bits (205), Expect = 3e-16 Identities = 86/332 (25%), Positives = 139/332 (41%), Gaps = 83/332 (25%) Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNR 247 GK+ ++ ++ DR + KG A++ +CE +S A Q++ E+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKA---------------QSALHEQKT 120 Query: 248 LAAMANNLQ------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTG 301 L M +Q + G +L+VG L+ +ED +R +FE FG I+ +++ D G Sbjct: 121 LPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-G 179 Query: 302 RSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE- 357 SKG F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 180 NSKGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKER 226 Query: 358 -------------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAA 390 + G+ G Q LMA +A+G L AA AAA Sbjct: 227 TMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAA 284 Query: 391 AAAQAAALQLNG--AVPL----GALNPAALTA 416 Q AAL +NG A P+ G P +TA Sbjct: 285 QMQQMAALNMNGLAAAPMTPTSGGSTPPGITA 316 >gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo sapiens] Length = 485 Score = 83.6 bits (205), Expect = 3e-16 Identities = 85/327 (25%), Positives = 142/327 (43%), Gaps = 64/327 (19%) Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 245 GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305 ++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193 Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 357 F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240 Query: 358 ---------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAAQA 395 + G+ G Q LMA +A+G L AA AAA Q Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQQM 298 Query: 396 AALQLNG--AVPL----GALNPAALTA 416 AAL +NG A P+ G P +TA Sbjct: 299 AALNMNGLAAAPMTPTSGGSTPPGITA 325 Score = 28.9 bits (63), Expect = 9.7 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 443 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 473 >gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sapiens] Length = 486 Score = 83.2 bits (204), Expect = 4e-16 Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%) Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 245 GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305 ++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193 Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 357 F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240 Query: 358 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 394 + G+ G Q LMA +A+G L AA AAA Q Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298 Query: 395 AAALQLNG--AVPL----GALNPAALTA 416 AAL +NG A P+ G P +TA Sbjct: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326 Score = 28.9 bits (63), Expect = 9.7 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 444 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 474 >gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo sapiens] Length = 370 Score = 82.4 bits (202), Expect = 7e-16 Identities = 51/178 (28%), Positives = 99/178 (55%), Gaps = 8/178 (4%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 226 VF L I + L + FSA GK+ +++SD + SKG A+V F + AI + Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157 Query: 227 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 286 G+ L G + V + K+R A + + + +Y+ + ++ ++ L+ +F + Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTN----VYIKNFGGDMDDERLKDVFSKY 213 Query: 287 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344 GK ++ +M DS +G+SKG+GF++F E A++A+E++NG ++ G+ + VG ++++ Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 12/163 (7%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L+D FS GK V++++D +S +SKG +V F ++ A+ + G+ + G I V Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264 Query: 241 SQAEKNRLAAMANNLQ-------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIV 293 +Q + R A + + +G G ++LY+ +L I ++ LR F FG I + Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323 Query: 294 LMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336 +M++ G+SKG+G I FS E A +A+ ++NG L +P+ + Sbjct: 324 VMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364 Score = 65.9 bits (159), Expect = 7e-11 Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 11/159 (6%) Query: 186 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 245 FS VG V +RI D+ +RRS G AYV F ++ A+ ++ + + Sbjct: 30 FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDII---------KGKS 80 Query: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305 RL + G +++ +L +I L F FGKI + +M D D G SKG Sbjct: 81 IRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD-DQG-SKG 138 Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344 Y F+ F + A RA+E++NG L G + VG R D Sbjct: 139 YAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177 Score = 51.6 bits (122), Expect = 1e-06 Identities = 26/72 (36%), Positives = 43/72 (59%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TED+L F G + +I + +D T RS GY ++ F A++AL+ + Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71 Query: 325 NGFELAGRPMRV 336 N + G+ +R+ Sbjct: 72 NFDIIKGKSIRL 83 >gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo sapiens] Length = 484 Score = 81.6 bits (200), Expect = 1e-15 Identities = 87/329 (26%), Positives = 142/329 (43%), Gaps = 69/329 (20%) Query: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLA-IGLTGQRLL---GVPIIVQASQA 243 GK+ ++ ++ DR + KG A++ +CE +S A L Q+ L PI V+ + + Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 244 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 303 E ++ + +L+VG L+ +ED +R +FE FG I+ +++ D G S Sbjct: 136 ESRG----GSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNS 190 Query: 304 KGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE--- 357 KG F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 191 KGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTM 237 Query: 358 -----------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAA 393 + G+ G Q LMA +A+G L AA AAA Sbjct: 238 RRMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQ 295 Query: 394 QAAALQLNG--AVPL----GALNPAALTA 416 Q AAL +NG A P+ G P +TA Sbjct: 296 QMAALNMNGLAAAPMTPTSGGSTPPGITA 324 Score = 28.9 bits (63), Expect = 9.7 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 306 YGFITFSDSECARRALEQLNGFELAGRPMRV 336 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 442 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 472 >gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a [Homo sapiens] Length = 475 Score = 81.3 bits (199), Expect = 2e-15 Identities = 88/337 (26%), Positives = 141/337 (41%), Gaps = 50/337 (14%) Query: 57 ETSKKKRSRSHNKSRDRKR-SRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRS 115 E +KRS S ++SRDRKR SRSRDR R R + S SR R+ + +R HG RS Sbjct: 21 ENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRS 79 Query: 116 RDHRREDRV--HYRSPPLA----TGYRYGHSKS--------------PHFREKSPVREPV 155 H ++ +V ++ PP T +Y ++ P +P PV Sbjct: 80 PRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPV 139 Query: 156 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSR 204 S R AR ++ + I + DFF+A + V V+I D+N Sbjct: 140 VG-SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-- 196 Query: 205 RSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM- 263 A++EF + A+ G G + ++ + L M+ N G + Sbjct: 197 ----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVS 251 Query: 264 --------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315 +L++G L + +D ++ + FG + L+KDS TG SKGY F + D Sbjct: 252 TVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDIN 311 Query: 316 CARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFP 352 +A+ LNG +L + + V + T ++ P Sbjct: 312 VTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPP 348 >gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform b [Homo sapiens] Length = 471 Score = 80.9 bits (198), Expect = 2e-15 Identities = 86/321 (26%), Positives = 136/321 (42%), Gaps = 50/321 (15%) Query: 57 ETSKKKRSRSHNKSRDRKR-SRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRS 115 E +KRS S ++SRDRKR SRSRDR R R + S SR R+ + +R HG RS Sbjct: 21 ENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRS 79 Query: 116 RDHRREDRV--HYRSPPLA----TGYRYGHSKS--------------PHFREKSPVREPV 155 H ++ +V ++ PP T +Y ++ P +P PV Sbjct: 80 PRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPV 139 Query: 156 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSR 204 S R AR ++ + I + DFF+A + V V+I D+N Sbjct: 140 VG-SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-- 196 Query: 205 RSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM- 263 A++EF + A+ G G + ++ + L M+ N G + Sbjct: 197 ----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVS 251 Query: 264 --------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315 +L++G L + +D ++ + FG + L+KDS TG SKGY F + D Sbjct: 252 TVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDIN 311 Query: 316 CARRALEQLNGFELAGRPMRV 336 +A+ LNG +L + + V Sbjct: 312 VTDQAIAGLNGMQLGDKKLLV 332 >gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] Length = 288 Score = 80.5 bits (197), Expect = 3e-15 Identities = 66/189 (34%), Positives = 88/189 (46%), Gaps = 33/189 (17%) Query: 31 KKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRS-----RSHNKSRDRKRSRSRDRDRYR 85 +++Y + S S SG+ + T + RS RS +KSR R SRSR R R Sbjct: 6 EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65 Query: 86 RRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHF 145 R +RSRS RSRS RR S S SRD+RR R+ HS SP Sbjct: 66 RHYTRSRS-------RSRS-HRRSRSRSYSRDYRR---------------RHSHSHSPMS 102 Query: 146 REKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRR 205 + R + +P+ VF + L RDL + FS G + DV I+ D+ SRR Sbjct: 103 TRR---RHVGNRANPDPNCCLGVFGLSLYT--TERDLREVFSKYGPIADVSIVYDQQSRR 157 Query: 206 SKGIAYVEF 214 S+G A+V F Sbjct: 158 SRGFAFVYF 166 Score = 51.6 bits (122), Expect = 1e-06 Identities = 27/72 (37%), Positives = 42/72 (58%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 L V L TE LR +F +G I ++ ++ D + RS+G+ F+ F + + A+ A E+ Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179 Query: 325 NGFELAGRPMRV 336 NG EL GR +RV Sbjct: 180 NGMELDGRRIRV 191 >gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo sapiens] Length = 631 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 325 NGFELAGRPMRV 336 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 325 NGFELAGRPMRV 336 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo sapiens] Length = 644 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 325 NGFELAGRPMRV 336 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 325 NGFELAGRPMRV 336 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo sapiens] Length = 660 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 344 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 264 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 325 NGFELAGRPMRV 336 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 325 NGFELAGRPMRV 336 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] Length = 375 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 11/183 (6%) Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220 ++ RT++ L+ + + FS +G + ++I++ S + +VEF E + Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61 Query: 221 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 279 A+ + G+++LG + K A ++ +K ++VG L IT + + Sbjct: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113 Query: 280 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 339 + F PFGKI + ++KD TG+SKGYGF++F + A A+ + G L GR +R Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173 Query: 340 TER 342 T + Sbjct: 174 TRK 176 Score = 68.2 bits (165), Expect = 1e-11 Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 23/182 (12%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227 VF L+ I D++ F+ GK+ D R++ D + +SKG +V F AI Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158 Query: 228 GQRLLG--------------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFN 273 G + LG P Q + ++ R + N N +Y G + Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKN---CTVYCGGIASG 215 Query: 274 ITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 333 +T+ ++R F PFG+I I + + KGY F+ FS E A A+ +NG + G Sbjct: 216 LTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHV 269 Query: 334 MR 335 ++ Sbjct: 270 VK 271 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Query: 255 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 314 + + +G P LYVG+L ++TE ++ +F G + ++ + + + Y F+ F + Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEH 58 Query: 315 ECARRALEQLNGFELAGRPMRVGHVT 340 A AL +NG ++ G+ ++V T Sbjct: 59 RDAAAALAAMNGRKILGKEVKVNWAT 84 Score = 29.6 bits (65), Expect = 5.7 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 15/98 (15%) Query: 127 RSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFF 186 R PP + ++K F + V+ SP+ TV+C +A+ + + + F Sbjct: 175 RKPPAPKSTQENNTKQLRFEDV------VNQSSPKNC---TVYCGGIASGLTDQLMRQTF 225 Query: 187 SAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAI 224 S G++ ++R+ + KG ++V F +S AI Sbjct: 226 SPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAI 257 >gi|188219593 TIA1 protein isoform 1 [Homo sapiens] Length = 375 Score = 77.4 bits (189), Expect = 2e-14 Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 11/183 (6%) Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220 E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 221 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 279 A+ + G++++G + K A ++ +K ++VG L IT + + Sbjct: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111 Query: 280 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 339 + F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171 Query: 340 TER 342 T + Sbjct: 172 TRK 174 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227 VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156 Query: 228 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276 G + LG P +++ + + + + + +Y G + +TE Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216 Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336 ++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++ Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 270 Query: 337 GHVTERLD 344 E LD Sbjct: 271 YWGKETLD 278 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 77.0 bits (188), Expect = 3e-14 Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 14/187 (7%) Query: 158 LSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEI 217 +S +DA TV+ L ++ L + F G V + + DR + + +G +VEF Sbjct: 6 ISERNQDA-TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64 Query: 218 QSVPLAIGLTGQ-RLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276 + AI + +L G PI V + A L AN +++G+L I E Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGAN-----------IFIGNLDPEIDE 113 Query: 277 DMLRGIFEPFGKI-DNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 335 +L F FG I +M+D DTG SKGY FI F+ + + A+E +NG L RP+ Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173 Query: 336 VGHVTER 342 V + ++ Sbjct: 174 VSYAFKK 180 Score = 58.9 bits (141), Expect = 9e-09 Identities = 34/98 (34%), Positives = 55/98 (56%), Gaps = 3/98 (3%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 +YVG L ++E +L +F G + N + KD TG+ +GYGF+ F E A A++ + Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74 Query: 325 NGFELAGRPMRVGHVT---ERLDGGTDITFPDGDQELD 359 N +L G+P+RV + + LD G +I + D E+D Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEID 112 >gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] Length = 636 Score = 77.0 bits (188), Expect = 3e-14 Identities = 59/231 (25%), Positives = 112/231 (48%), Gaps = 22/231 (9%) Query: 134 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 179 GY Y + + P E++ PVR P R + +F L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDN 112 Query: 180 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 238 + L D FSA G + +++ D N SKG +V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170 Query: 239 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 298 ++ K R A + ++ +Y+ + ++ ++ L+ +F FG ++ +M D Sbjct: 171 GRFKSRKEREAELGARAKEFTN----VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD- 225 Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDI 349 ++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++ T++ Sbjct: 226 ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL 276 Score = 72.8 bits (177), Expect = 6e-13 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%) Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211 +E L ++ V+ + L+D F G V++++D S +SKG + Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235 Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 264 V F + A+ + G+ L G I V +Q + R + ++ + Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN 295 Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 325 NGFELAGRPMRV 336 NG +A +P+ V Sbjct: 354 NGRIVATKPLYV 365 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 13/162 (8%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L + FS G + +R+ D +RRS G AYV F + A+ + + G P+ + Sbjct: 27 LYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMW 86 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NIFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342 SKGYGF+ F E A RA+E++NG L R + VG R Sbjct: 135 NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 57.8 bits (138), Expect = 2e-08 Identities = 30/72 (41%), Positives = 43/72 (59%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TE ML F P G I +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 325 NGFELAGRPMRV 336 N + G+P+R+ Sbjct: 73 NFDVIKGKPVRI 84 >gi|20373175 musashi 2 isoform a [Homo sapiens] Length = 328 Score = 76.6 bits (187), Expect = 4e-14 Identities = 64/263 (24%), Positives = 114/263 (43%), Gaps = 23/263 (8%) Query: 162 ERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVP 221 + D +F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV Sbjct: 17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75 Query: 222 LAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRG 281 ++LG P S+ ++A K +++VG L N + ++ Sbjct: 76 -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128 Query: 282 IFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTE 341 FE FGK+++ +LM D T R +G+GF+TF + + + E ++ E+ + + Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE-IHFHEINNKMVECKKAQP 187 Query: 342 RLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGI----QLPSTAAAAAAAAAQAAA 397 + ++ FP G + G A G M G G+ +T A + Sbjct: 188 K-----EVMFPPGTR----GRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYG 238 Query: 398 LQLNGAVPLGALNPAALTALSPA 420 Q G P A P A A++ A Sbjct: 239 YQFPG-FPAAAYGPVAAAAVAAA 260 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/80 (31%), Positives = 42/80 (52%) Query: 244 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 303 E N + + P ++++G L + + D LR F FG+I ++M+D T RS Sbjct: 2 EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61 Query: 304 KGYGFITFSDSECARRALEQ 323 +G+GF+TF+D + L Q Sbjct: 62 RGFGFVTFADPASVDKVLGQ 81 >gi|188219591 TIA1 protein isoform 2 [Homo sapiens] Length = 386 Score = 75.9 bits (185), Expect = 7e-14 Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 8/187 (4%) Query: 161 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 220 E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 221 PLAIG-LTGQRLLGVPIIVQ----ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNIT 275 A+ + G++++G + V S +K+ ++ + Q+ ++VG L IT Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDH-FHVFVGDLSPEIT 118 Query: 276 EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 335 + ++ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178 Query: 336 VGHVTER 342 T + Sbjct: 179 TNWATRK 185 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227 VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167 Query: 228 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276 G + LG P +++ + + + + + +Y G + +TE Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227 Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 336 ++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++ Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 281 Query: 337 GHVTERLD 344 E LD Sbjct: 282 YWGKETLD 289 >gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo sapiens] Length = 420 Score = 75.9 bits (185), Expect = 7e-14 Identities = 70/262 (26%), Positives = 114/262 (43%), Gaps = 32/262 (12%) Query: 76 SRSRDRDRYRRRNSRSRSPGRQC--------RHRSRSWDRRHGSES---RSRDHRREDRV 124 S +R R +R+ ++ P R R R RRH S RS R Sbjct: 48 SSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRT 107 Query: 125 HYRSPPLATGYRYG----HSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 + PP + +S F E S + N S ++D +F L+ + Sbjct: 108 ARQHPPADSSVTMEDMNEYSNIEEFAEGSKI-----NASKNQQDDGKMFIGGLSWDTSKK 162 Query: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 DL ++ S G+V D I +D + RS+G +V F + SV + L +L G I + Sbjct: 163 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR 222 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 ++A KG P +++VG L + +E+ ++ F FG+I+NI L D+ T Sbjct: 223 AKA------------LKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKT 270 Query: 301 GRSKGYGFITFSDSECARRALE 322 +G+ FIT++D E ++ LE Sbjct: 271 NERRGFCFITYTDEEPVKKLLE 292 >gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] Length = 631 Score = 75.5 bits (184), Expect = 9e-14 Identities = 49/183 (26%), Positives = 96/183 (52%), Gaps = 8/183 (4%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 226 +F L I + L D SA G + ++ D N SKG +V F ++ AI + Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158 Query: 227 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 286 G L G + V ++ K R A + ++ +Y+ + ++ ++ L+ +F F Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPN----VYIKNFGEDMDDERLKDLFGKF 214 Query: 287 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGG 346 G ++ +M D ++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++ Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273 Query: 347 TDI 349 T++ Sbjct: 274 TEL 276 Score = 73.2 bits (178), Expect = 4e-13 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%) Query: 152 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 211 +E L ++ V+ + L+D F G V++++D S +SKG + Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235 Query: 212 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 264 V F + A+ + G+ L G I V +Q + R + ++ + Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 295 Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 325 NGFELAGRPMRV 336 NG +A +P+ V Sbjct: 354 NGRIVATKPLYV 365 Score = 57.4 bits (137), Expect = 3e-08 Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 17/164 (10%) Query: 182 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 240 L + FS G + +RI D + S AYV F + A+ + + G P+ + Sbjct: 27 LYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMW 86 Query: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKI--DNIVLMKDS 298 SQ + +L+K G ++V +L +I L FG I N+V Sbjct: 87 SQRDP--------SLRKSGVG--NIFVKNLDKSINNKALYDTVSAFGNILSCNVV----C 132 Query: 299 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 342 D SKGYGF+ F E A RA++++NG L GR + VG R Sbjct: 133 DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSR 176 Score = 53.5 bits (127), Expect = 4e-07 Identities = 27/72 (37%), Positives = 42/72 (58%) Query: 265 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 324 LYVG LH ++TE ML F P G I +I + +D T S Y ++ F ++ A AL+ + Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72 Query: 325 NGFELAGRPMRV 336 N + G+P+R+ Sbjct: 73 NFDVIKGKPVRI 84 >gi|25121993 musashi 2 isoform b [Homo sapiens] Length = 251 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 8/155 (5%) Query: 168 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 227 +F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV Sbjct: 19 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71 Query: 228 GQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFG 287 ++LG P S+ ++A K +++VG L N + ++ FE FG Sbjct: 72 -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130 Query: 288 KIDNIVLMKDSDTGRSKGYGFITFSDSECARRALE 322 K+++ +LM D T R +G+GF+TF + + + E Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165 Score = 52.0 bits (123), Expect = 1e-06 Identities = 22/60 (36%), Positives = 37/60 (61%) Query: 264 RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 323 ++++G L + + D LR F FG+I ++M+D T RS+G+GF+TF+D + L Q Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77 >gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform B1 [Homo sapiens] Length = 353 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 8/170 (4%) Query: 147 EKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRS 206 EK+ P++ E+ R +F L+ L +++ GK+ D ++ D S+RS Sbjct: 2 EKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS 61 Query: 207 KGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMR-L 265 +G +V F + V A+ P + E R A + + G ++ L Sbjct: 62 RGFGFVTFSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKL 114 Query: 266 YVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315 +VG + + E LR FE +GKID I ++ D +G+ +G+GF+TF D + Sbjct: 115 FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD 164 >gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b [Homo sapiens] Length = 285 Score = 74.3 bits (181), Expect = 2e-13 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%) Query: 157 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 216 N S E DA +F L+ +DL+D+F+ G+V D I D N+ RS+G ++ F + Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120 Query: 217 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 276 SV + RL G I + + AM + K +++VG L+ TE Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167 Query: 277 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 323 + +R F FG+I+ I L D + +G+ FITF + E ++ LE+ Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,470,709 Number of Sequences: 37866 Number of extensions: 776501 Number of successful extensions: 12468 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 457 Number of HSP's successfully gapped in prelim test: 221 Number of HSP's that attempted gapping in prelim test: 5546 Number of HSP's gapped (non-prelim): 3128 length of query: 439 length of database: 18,247,518 effective HSP length: 105 effective length of query: 334 effective length of database: 14,271,588 effective search space: 4766710392 effective search space used: 4766710392 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.