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Search of human proteins with 224465182
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens] 1032 0.0
gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens] 1030 0.0
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] 1030 0.0
gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens] 955 0.0
gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact... 585 e-167
gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens] 577 e-165
gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens] 497 e-141
gi|93004092 nuclear factor I/B [Homo sapiens] 483 e-136
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 62 2e-09
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 59 1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 52 1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 52 1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 52 1e-06
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 52 2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 51 2e-06
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 51 2e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 51 2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 51 2e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 51 3e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 4e-06
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 50 5e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 50 6e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 50 6e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 50 6e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 50 6e-06
gi|50345997 E1A binding protein p300 [Homo sapiens] 49 8e-06
>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
Length = 501
Score = 1032 bits (2668), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVK 60
MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVK
Sbjct: 1 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVK 60
Query: 61 QKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWR 120
QKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWR
Sbjct: 61 QKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWR 120
Query: 121 LDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADS 180
LDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADS
Sbjct: 121 LDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADS 180
Query: 181 SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD 240
SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD
Sbjct: 181 SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD 240
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS 300
LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS
Sbjct: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS 300
Query: 301 GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTL 360
GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTL
Sbjct: 301 GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTL 360
Query: 361 HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 420
HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH
Sbjct: 361 HFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 420
Query: 421 NPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
NPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS
Sbjct: 421 NPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
Query: 481 VGPRDPSFVNIPQQTQSWYLG 501
VGPRDPSFVNIPQQTQSWYLG
Sbjct: 481 VGPRDPSFVNIPQQTQSWYLG 501
>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
Length = 554
Score = 1030 bits (2663), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ
Sbjct: 55 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 114
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 115 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 174
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS
Sbjct: 175 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 234
Query: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241
QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL
Sbjct: 235 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 294
Query: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301
ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG
Sbjct: 295 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 354
Query: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH
Sbjct: 355 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN
Sbjct: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV
Sbjct: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
Query: 482 GPRDPSFVNIPQQTQSWYLG 501
GPRDPSFVNIPQQTQSWYLG
Sbjct: 535 GPRDPSFVNIPQQTQSWYLG 554
>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
Length = 509
Score = 1030 bits (2663), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ
Sbjct: 10 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 70 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS
Sbjct: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189
Query: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241
QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL
Sbjct: 190 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 249
Query: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301
ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG
Sbjct: 250 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 309
Query: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH
Sbjct: 310 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN
Sbjct: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV
Sbjct: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489
Query: 482 GPRDPSFVNIPQQTQSWYLG 501
GPRDPSFVNIPQQTQSWYLG
Sbjct: 490 GPRDPSFVNIPQQTQSWYLG 509
>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
Length = 498
Score = 955 bits (2469), Expect = 0.0
Identities = 468/485 (96%), Positives = 469/485 (96%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ
Sbjct: 10 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 70 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS
Sbjct: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189
Query: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241
QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL
Sbjct: 190 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 249
Query: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301
ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG
Sbjct: 250 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 309
Query: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH
Sbjct: 310 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN
Sbjct: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP A+
Sbjct: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIKVAASHHPPD 489
Query: 482 GPRDP 486
P DP
Sbjct: 490 RPPDP 494
>gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor)
[Homo sapiens]
Length = 441
Score = 585 bits (1508), Expect = e-167
Identities = 303/413 (73%), Positives = 342/413 (82%), Gaps = 13/413 (3%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPE+KQ
Sbjct: 10 DEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQ 69
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIRPE+REDFVLT+TGKKPPCCVLSNPDQKGK+RRIDCLRQADKVWRL
Sbjct: 70 KWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRL 129
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERL KSPQCSNPGLCVQPHHIGV++KELDLYLAYFVH +S
Sbjct: 130 DLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESG 189
Query: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241
QS+S +Q DADIK P NGHL FQD FVTSGV++VTELVRVSQTP+A +GPNFSL+DL
Sbjct: 190 QSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADL 248
Query: 242 ESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQGRSPGSG-SQ 298
ES SYY+++ + RRS+ S STS+TKR KS++D EM+SP ++ FY G GRSP +G SQ
Sbjct: 249 ESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQ 308
Query: 299 SSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR-ASPHAT 356
SSGW ++V+ G P +LKKS K F S SQ SS AFT H PV+ G R SP AT
Sbjct: 309 SSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRAT 365
Query: 357 PSTLHFPTSPIIQQPGPYFSHPAIRY---HPQETLKEFVQLVCPD-AGQQAGQ 405
S LHFP++ IIQQ PYF+HP IRY H Q++LKEFVQ VC D +GQ GQ
Sbjct: 366 ASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQ 418
>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
Length = 499
Score = 577 bits (1488), Expect = e-165
Identities = 325/519 (62%), Positives = 379/519 (73%), Gaps = 38/519 (7%)
Query: 1 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVK 60
MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVK
Sbjct: 1 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK 60
Query: 61 QKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWR 120
QKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWR
Sbjct: 61 QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR 120
Query: 121 LDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADS 180
LDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV D+
Sbjct: 121 LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDA 180
Query: 181 SQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSL 238
QS SP +D +D FQ+SFVTSGVFSVTEL++VS+TP+ GTGPNFSL
Sbjct: 181 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSL 240
Query: 239 SDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGS 295
+L+ Y ++P + +RR+LPSTSS+ S + + S+E+++D+ +YT SP S
Sbjct: 241 GELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSS 296
Query: 296 GSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPR 350
+ SS W E +E G+ SP + +KS F+SPSP + L ++FTQHHRPVI +G
Sbjct: 297 PTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIA 355
Query: 351 ASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQ 405
SPH + S LHFPT+ I+ Q YF H AIRY +PQ+ LK+ V L C A QQ G
Sbjct: 356 RSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 414
Query: 406 VGFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPT 463
+ NGS Q K+ + L ML PPPP P +A P P TKP TTS EGGA SPT
Sbjct: 415 L-----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPT 463
Query: 464 SPTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 501
SP+YS P TSPANR FV +GPRDP+ + Q QSWYLG
Sbjct: 464 SPSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499
>gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
Length = 428
Score = 497 bits (1280), Expect = e-141
Identities = 271/423 (64%), Positives = 318/423 (75%), Gaps = 21/423 (4%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 11 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 70
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 71 KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 130
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV D+
Sbjct: 131 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 190
Query: 182 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 239
QS SP +D +D FQ+SFVTSGVFSVTEL++VS+TP+ GTGPNFSL
Sbjct: 191 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 250
Query: 240 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 296
+L+ Y ++P + +RR+LPSTSS+ S + + S+E+++D+ +YT SP S
Sbjct: 251 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 306
Query: 297 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 351
+ SS W E +E G+ SP + +KS F+SPSP + L ++FTQHHRPVI +G
Sbjct: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 365
Query: 352 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 406
SPH + S LHFPT+ I+ Q YF H AIRY +PQ+ LK+ V L C A QQ G
Sbjct: 366 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPS 424
Query: 407 GFL 409
+L
Sbjct: 425 WYL 427
>gi|93004092 nuclear factor I/B [Homo sapiens]
Length = 420
Score = 483 bits (1244), Expect = e-136
Identities = 266/412 (64%), Positives = 304/412 (73%), Gaps = 22/412 (5%)
Query: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61
DEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELLSEKPE+KQ
Sbjct: 11 DEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQ 70
Query: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121
KWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCLRQADKVWRL
Sbjct: 71 KWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRL 130
Query: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181
DLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LAY+V DS
Sbjct: 131 DLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSG 190
Query: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241
QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI GTG NF + ++
Sbjct: 191 QSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEI 244
Query: 242 ESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 299
S YY M+ G ++RSL S S+ K + S+++ M+ FY SP +GS++
Sbjct: 245 PSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS-SPAAGSRT 302
Query: 300 SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHAT--- 356
WHE + M SPTT+KK EK FSS SP +S + F QHH P I G S +T
Sbjct: 303 --WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTP 360
Query: 357 --PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQ 401
PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Q
Sbjct: 361 PPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 61.6 bits (148), Expect = 2e-09
Identities = 98/366 (26%), Positives = 132/366 (36%), Gaps = 26/366 (7%)
Query: 133 PLESTDGERLVKSPQCSNPGLCVQPHHIGVSV----KELDLYLAYFVHAADSSQSESPSQ 188
P + G SP +PG + P + S + Y + +S S SP+
Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626
Query: 189 PSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYS 248
PS + + TS +S T +P + T P++S + S SY
Sbjct: 1627 PSYSPTSPNYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPSYSP 1680
Query: 249 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 308
SP S PS S TS + S SP P T SP S S S P
Sbjct: 1681 TSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPT 1737
Query: 309 MPS--PTTLKKSEKSGF---SSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFP 363
PS PT+ S S +SPS S TS + + ++ P T P SP +PS + P
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP--TSPNYSP-TSPS--YSP 1792
Query: 364 TSPIIQQPGPYFSHPAIRYHPQE-TLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 422
TSP P +S + RY PQ T P + + P S
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 482
+ PT P P + P P + PT S SPTSPTYS S
Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTS--PTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS 1910
Query: 483 PRDPSF 488
P P++
Sbjct: 1911 PTSPTY 1916
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/307 (27%), Positives = 111/307 (36%), Gaps = 37/307 (12%)
Query: 180 SSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 239
+S S SP+ PS + + TS +S T +P + T PN+S +
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1751
Query: 240 DLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 299
S +Y SP S PS S TS S SP P T SP S S S
Sbjct: 1752 ---SPNYTPTSPSYSPTS-PSYSPTSPNYTPTSPNYSPTSPSYSP--TSPSYSPTSPSYS 1805
Query: 300 SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPST 359
P SPT S SSPS S TS T + + P +SP TP++
Sbjct: 1806 PSSPRYTP--QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP------SSPEYTPTS 1857
Query: 360 LHF-PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 418
+ PTSP P +S + Y P + +P S
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTP-----------------KYSPTSPTYSPTSP 1900
Query: 419 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRF 478
V+ P P P P P P T PT S +G SPTSP YS S + +
Sbjct: 1901 VYTPTSPK-YSPTSPTYSPTSPKYSPTSPTYSPT-SPKGSTYSPTSPGYSPTSPTYSLTS 1958
Query: 479 VSVGPRD 485
++ P D
Sbjct: 1959 PAISPDD 1965
Score = 53.1 bits (126), Expect = 6e-07
Identities = 70/265 (26%), Positives = 97/265 (36%), Gaps = 39/265 (14%)
Query: 224 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEE 283
+ TP G P + S M+PGA S PS +S +S SPG
Sbjct: 1516 AMTPWNQGATPAYGAWSPSVGS--GMTPGAAGFS-PSAASDASGF----------SPGYS 1562
Query: 284 PFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHR 343
P ++ SPGS SS P +PSP G SPS S TS +
Sbjct: 1563 PAWSPTPGSPGSPGPSS------PYIPSP--------GGAMSPSYSPTSPA----YEPRS 1604
Query: 344 PVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 403
P P++ ++ S + PTSP P +S + Y P P + +
Sbjct: 1605 PGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS------PTSPSYS 1658
Query: 404 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT 463
+P S + PT P P + P P + P+ S + SPT
Sbjct: 1659 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPT 1716
Query: 464 SPTYSTPSTSPANRFVSVGPRDPSF 488
SP+YS S S + S P PS+
Sbjct: 1717 SPSYSPTSPSYSPTSPSYSPTSPSY 1741
Score = 45.8 bits (107), Expect = 9e-05
Identities = 72/273 (26%), Positives = 98/273 (35%), Gaps = 39/273 (14%)
Query: 230 AGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRL-KSVEDEMD--SPGEEPFY 286
AGTG L D E Y P ++P + T S M SP P+
Sbjct: 1466 AGTGCFDLLLDAEKCKYGMEIP----TNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWN 1521
Query: 287 TGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS-------SPSPSQTSSLGTAFT 339
G + G+ S S G + PG + S+ SGFS SP+P S G +
Sbjct: 1522 QGATPAYGAWSPSVG-SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPS-- 1578
Query: 340 QHHRPVITGPRASPHATPSTLHFPTSPIIQ--QPGPYFSHPAIRYHPQETLKEFVQLVCP 397
P I SP S + PTSP + PG Y + + Y P P
Sbjct: 1579 ---SPYIP----SPGGAMSPSYSPTSPAYEPRSPGGY-TPQSPSYSPTS----------P 1620
Query: 398 DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP--PTTST 455
+ +PN S ++P P+ P P + P P P+ S
Sbjct: 1621 SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1680
Query: 456 EGGAASPTSPTYSTPSTSPANRFVSVGPRDPSF 488
+ SPTSP+YS S S + S P PS+
Sbjct: 1681 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1713
Score = 39.7 bits (91), Expect = 0.006
Identities = 54/197 (27%), Positives = 75/197 (38%), Gaps = 23/197 (11%)
Query: 211 TSGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPGAMRRSLPSTSSTSST 267
TS +S T +P + T P++S S S Y+ S + S PS S TS
Sbjct: 1779 TSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPK 1838
Query: 268 KRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMP--SPTTLKKSEKSGFSS 325
S SP P T SP S S + P P SPTT K S +S
Sbjct: 1839 YTPTSPSYSPSSPEYTP--TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP----TS 1892
Query: 326 PSPSQTSSLGTAFTQHHRPVI------------TGPRASPHATPSTLHFPTSPIIQQPGP 373
P+ S TS + T + + P T P SP + + + PTSP P
Sbjct: 1893 PTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSP 1952
Query: 374 YFSHPAIRYHPQETLKE 390
+S + P ++ +E
Sbjct: 1953 TYSLTSPAISPDDSDEE 1969
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 326 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 385
PS TSSL + T P + P P P P Q P HPA P
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387
Query: 386 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 445
VQ P + A + + QG+V LPPPPPPP PLP
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434
Query: 446 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 489
P +P + T A P S + TPST+P + P PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)
Query: 407 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 454
G + S P +P PPPPPP M P PVP PP +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361
Query: 455 TEGGAASPTSP 465
A P P
Sbjct: 362 ALQAPAVPPPP 372
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/51 (33%), Positives = 21/51 (41%)
Query: 425 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 475
P + P PPPPP P L + TST P P +T +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367
Score = 29.6 bits (65), Expect = 6.7
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 431 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
PPPPPPM A+P+P + + A+ +P + +P+ P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 326 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 385
PS TSSL + T P + P P P P Q P HPA P
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387
Query: 386 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 445
VQ P + A + + QG+V LPPPPPPP PLP
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434
Query: 446 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 489
P +P + T A P S + TPST+P + P PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)
Query: 407 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 454
G + S P +P PPPPPP M P PVP PP +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361
Query: 455 TEGGAASPTSP 465
A P P
Sbjct: 362 ALQAPAVPPPP 372
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/51 (33%), Positives = 21/51 (41%)
Query: 425 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 475
P + P PPPPP P L + TST P P +T +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367
Score = 29.6 bits (65), Expect = 6.7
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 431 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
PPPPPPM A+P+P + + A+ +P + +P+ P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 326 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 385
PS TSSL + T P + P P P P Q P HPA P
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387
Query: 386 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 445
VQ P + A + + QG+V LPPPPPPP PLP
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434
Query: 446 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 489
P +P + T A P S + TPST+P + P PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)
Query: 407 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 454
G + S P +P PPPPPP M P PVP PP +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361
Query: 455 TEGGAASPTSP 465
A P P
Sbjct: 362 ALQAPAVPPPP 372
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/51 (33%), Positives = 21/51 (41%)
Query: 425 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 475
P + P PPPPP P L + TST P P +T +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367
Score = 29.6 bits (65), Expect = 6.7
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 431 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
PPPPPPM A+P+P + + A+ +P + +P+ P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 326 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 385
PS TSSL + T P + P P P P Q P HPA P
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387
Query: 386 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 445
VQ P + A + + QG+V LPPPPPPP PLP
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434
Query: 446 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 489
P +P + T A P S + TPST+P + P PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)
Query: 407 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 454
G + S P +P PPPPPP M P PVP PP +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361
Query: 455 TEGGAASPTSP 465
A P P
Sbjct: 362 ALQAPAVPPPP 372
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/51 (33%), Positives = 21/51 (41%)
Query: 425 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 475
P + P PPPPP P L + TST P P +T +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367
Score = 29.6 bits (65), Expect = 6.7
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 431 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
PPPPPPM A+P+P + + A+ +P + +P+ P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 54.7 bits (130), Expect = 2e-07
Identities = 75/301 (24%), Positives = 103/301 (34%), Gaps = 61/301 (20%)
Query: 224 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 282
S P GP S+S S SP A RR S +++ L S + SP
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 283 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPT------TLKKSEKSGFSSPSPSQ--- 330
P G R+P SQ G + P +P L S ++PSPS
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 331 ---------------------TSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 369
T+SLG+ Q + P SP ATP P +P
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAP--- 358
Query: 370 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 429
P + P ++ P P A + +P + VH L P
Sbjct: 359 ---PALALPPLQAPPS-----------PPASPPLSPLATPSPQAPNALAVH--LLQAPFS 402
Query: 430 PPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRD 485
PPP PP P + P PV P PP+ + AA P S P++ P + + P+
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462
Query: 486 P 486
P
Sbjct: 463 P 463
Score = 43.1 bits (100), Expect = 6e-04
Identities = 59/255 (23%), Positives = 93/255 (36%), Gaps = 34/255 (13%)
Query: 242 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
E+ ++S GA R + P T S + +R ++ E+ P P + + G
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 299 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 357
S E PSP ++ S G P+ SS T + P +GP A TP
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS---PARSGPSA--RGTP 254
Query: 358 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 417
P+ P + G P PQ T P A +G L+ + +
Sbjct: 255 RAPAHPSQP--KPKGLQALRP-----PQVT---------PPRKDAAPALGPLSSSPLAT- 297
Query: 418 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANR 477
P+P PP P P + LP P PP+ +T + T+S + P +
Sbjct: 298 -------PSPSAPPSPSAPPSLQT-LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 478 FVSVGPRDPSFVNIP 492
+ P+ P + +P
Sbjct: 350 LATPPPQAPPALALP 364
Score = 36.2 bits (82), Expect = 0.071
Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
SP A S +TS S T L++ + SP P T ++P + + + P
Sbjct: 317 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 367
Query: 310 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 357
P+ S ++PSP ++L F+ P + P SP ATP
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427
Query: 358 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 401
+ L P SP P P + P + P + K Q P A
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 485
Query: 402 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 455
+P S G+ PF P+ LP PPP P PL PP + T
Sbjct: 486 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 456 EGGAASPTSPTYSTPSTSP 474
P +P T + P
Sbjct: 544 LQAPRRPPTPGPDTSVSGP 562
Score = 30.8 bits (68), Expect = 3.0
Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 324 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 379
+ P P +L T Q P + P +P + ++L P SP+ P P + P
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 531
Query: 380 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 439
++ P +Q A ++ P V P L + P PPPPP
Sbjct: 532 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 440 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 484
P L PD ++S EGGAA+ P + PA S GP
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 637
Query: 485 DP-SFVNIPQQTQSW 498
P +F P W
Sbjct: 638 PPLAFRGAPGAPLPW 652
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)
Query: 217 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 274
+ E +R S +P AA T N S ++ S + A S P S+ +++ S
Sbjct: 48 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 104
Query: 275 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 328
+E D + T + P S S+ G + G P + + +S S PSP
Sbjct: 105 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 164
Query: 329 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 380
SS Q P + TG +P + P P +P + PGP S A+
Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 219
Query: 381 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 440
PQ + P A Q Q P + H P L P PP P
Sbjct: 220 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 260
Query: 441 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
P P P PP G A P++P+++ P
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 290
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)
Query: 283 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 328
+P GQG PG S +G PG P P L G + SP+ P
Sbjct: 289 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347
Query: 329 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 387
+ S+L + +P+ P A PH P PT+PI Q P P HP P
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 403
Query: 388 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 434
L P A + + +P + + P +P PP PPP
Sbjct: 404 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462
Query: 435 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 483
P P L +PP GG T PT + ST PA S P
Sbjct: 463 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
Score = 33.5 bits (75), Expect = 0.46
Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)
Query: 234 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 293
P + SD +SS+ M T T + ++ +PG P T P
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 220
Query: 294 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 342
GS ++ +P P+ P + S P PS H
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 269
Query: 343 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 394
P+ +TG P A HA P LH P P Q GP HP P +
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 319
Query: 395 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 450
+ P A Q +G P+ S Q L + P P P P PL +P KP
Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 376
Query: 451 PTTSTEGGAASPTS----PTYSTPSTSPAN 476
P T+ +P + P S PS N
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)
Query: 217 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 274
+ E +R S +P AA T N S ++ S + A S P S+ +++ S
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658
Query: 275 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 328
+E D + T + P S S+ G + G P + + +S S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718
Query: 329 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 380
SS Q P + TG +P + P P +P + PGP S A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773
Query: 381 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 440
PQ + P A Q Q P + H P L P PP P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814
Query: 441 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
P P P PP G A P++P+++ P
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)
Query: 283 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 328
+P GQG PG S +G PG P P L G + SP+ P
Sbjct: 843 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901
Query: 329 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 387
+ S+L + +P+ P A PH P PT+PI Q P P HP P
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957
Query: 388 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 434
L P A + + +P + + P +P PP PPP
Sbjct: 958 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
Query: 435 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 483
P P L +PP GG T PT + ST PA S P
Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Score = 33.5 bits (75), Expect = 0.46
Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)
Query: 234 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 293
P + SD +SS+ M T T + ++ +PG P T P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774
Query: 294 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 342
GS ++ +P P+ P + S P PS H
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823
Query: 343 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 394
P+ +TG P A HA P LH P P Q GP HP P +
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873
Query: 395 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 450
+ P A Q +G P+ S Q L + P P P P PL +P KP
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930
Query: 451 PTTSTEGGAASPTS----PTYSTPSTSPAN 476
P T+ +P + P S PS N
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)
Query: 217 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 274
+ E +R S +P AA T N S ++ S + A S P S+ +++ S
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658
Query: 275 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 328
+E D + T + P S S+ G + G P + + +S S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718
Query: 329 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 380
SS Q P + TG +P + P P +P + PGP S A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773
Query: 381 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 440
PQ + P A Q Q P + H P L P PP P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814
Query: 441 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
P P P PP G A P++P+++ P
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)
Query: 283 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 328
+P GQG PG S +G PG P P L G + SP+ P
Sbjct: 843 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901
Query: 329 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 387
+ S+L + +P+ P A PH P PT+PI Q P P HP P
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957
Query: 388 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 434
L P A + + +P + + P +P PP PPP
Sbjct: 958 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
Query: 435 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 483
P P L +PP GG T PT + ST PA S P
Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Score = 33.5 bits (75), Expect = 0.46
Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)
Query: 234 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 293
P + SD +SS+ M T T + ++ +PG P T P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774
Query: 294 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 342
GS ++ +P P+ P + S P PS H
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823
Query: 343 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 394
P+ +TG P A HA P LH P P Q GP HP P +
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873
Query: 395 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 450
+ P A Q +G P+ S Q L + P P P P PL +P KP
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930
Query: 451 PTTSTEGGAASPTS----PTYSTPSTSPAN 476
P T+ +P + P S PS N
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 51.6 bits (122), Expect = 2e-06
Identities = 61/262 (23%), Positives = 93/262 (35%), Gaps = 28/262 (10%)
Query: 232 TGPNFSLSDLESSSYYSMSPGAMRRSLPS-----TSSTSSTKRLKSVEDEMDSPGEEPFY 286
T P+F+LS +SS +++P LP+ TS S+ + S+ + E
Sbjct: 1065 TSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT 1124
Query: 287 TGQGRSPGSGSQSSGWHEVEPG-MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 345
+P S + S +P P PTT + +P ++L T H P
Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDP------TMAPDPITTLNPTVTPHF-PT 1177
Query: 346 ITGPRASPHATPST--LHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 403
P +PH T T P QP +H + P T + F +
Sbjct: 1178 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237
Query: 404 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPP---------PPPMARPVPL--PVPDTKPPT 452
P+ ++ H+ +P P P P P P P P P P T P
Sbjct: 1238 TPHPTTTPHPTTI--THSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP 1295
Query: 453 TSTEGGAASPTSPTYSTPSTSP 474
T+T +P T P+T+P
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTTP 1317
Score = 38.1 bits (87), Expect = 0.019
Identities = 54/240 (22%), Positives = 73/240 (30%), Gaps = 34/240 (14%)
Query: 288 GQGRSPGS----------GSQSSGWHEVEPGMPS-----PTTLKKSEKSGFSSPSPSQTS 332
G RSPGS GS W E P P+ P T + P P+ TS
Sbjct: 965 GTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTS 1024
Query: 333 SLGTAFTQHHRPVITGPRASPHATPSTLH--FPTSPIIQQPGPYFSH--------PAIRY 382
T H +P +P T T+P + P F+ PA+
Sbjct: 1025 DSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTP 1084
Query: 383 HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN-PFLPTPMLPP--------PP 433
P T + +V L+P + P L T P
Sbjct: 1085 EPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPD 1144
Query: 434 PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQ 493
P P P P P P +T +P PT P+T+P ++ P PQ
Sbjct: 1145 PSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQ 1204
Score = 34.7 bits (78), Expect = 0.21
Identities = 43/184 (23%), Positives = 65/184 (35%), Gaps = 25/184 (13%)
Query: 310 PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 369
P PTT + + +P T++ T H P P ++P T T+ PTS +
Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPH--PTTPDPSSTPVIT--TVSLPTSLGTE 1348
Query: 370 QPGPYFSHPAIR--YHPQETLKEFVQLVCPDAGQQAGQVGFL--------NPNGSSQGKV 419
P + P ++ HPQ T P Q+ L +P+ SS
Sbjct: 1349 LSSPTLA-PTVKPSLHPQLTF------TAPAPHTSTSQIPTLEPSPALESSPSRSSTATS 1401
Query: 420 HNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFV 479
+P PP P P P P + T + SPT+ P P +
Sbjct: 1402 MDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDP----L 1457
Query: 480 SVGP 483
++GP
Sbjct: 1458 TLGP 1461
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/310 (24%), Positives = 101/310 (32%), Gaps = 49/310 (15%)
Query: 224 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 282
S P GP S+S S SP A RR S +++ L S + SP
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 283 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 339
P G R+P SQ G + P +P + G S SP T S A
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314
Query: 340 QHHRPVITG---------------PRA--SPHATPSTLHFPT--------------SPII 368
P + P A SP A PS P+ SP +
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 369 QQPGPYFSHPAI--------RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 420
Q + P + + P L P A + +P + VH
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Query: 421 NPFLPTPMLPPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPAN 476
L P PPP PP P + P PV P PP+ + AA P S P++ P +
Sbjct: 435 --LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 477 RFVSVGPRDP 486
+ P+ P
Sbjct: 493 PSATPPPQAP 502
Score = 46.6 bits (109), Expect = 5e-05
Identities = 67/271 (24%), Positives = 96/271 (35%), Gaps = 36/271 (13%)
Query: 242 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
E+ ++S GA R + P T S + +R ++ E+ P P + + G
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 299 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHR--PVITG-PRASPH 354
S E PSP ++ S G P+ SS T + R P G PRA H
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 355 AT---PSTLHFPTSPIIQQP--------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 403
+ P L P + P GP S P P L+ P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP------ 322
Query: 404 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPV--PLPVPDTKPPTTSTEGGAAS 461
P+ SS L TP LP PP P A P LP P PP+ +T +
Sbjct: 323 -----ATPHSSSL----TCQLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372
Query: 462 PTSPTYSTPSTSPANRFVSVGPRDPSFVNIP 492
T+S + P + + P+ P + +P
Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Score = 36.2 bits (82), Expect = 0.071
Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
SP A S +TS S T L++ + SP P T ++P + + + P
Sbjct: 356 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 406
Query: 310 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 357
P+ S ++PSP ++L F+ P + P SP ATP
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 358 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 401
+ L P SP P P + P + P + K Q P A
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 524
Query: 402 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 455
+P S G+ PF P+ LP PPP P PL PP + T
Sbjct: 525 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582
Query: 456 EGGAASPTSPTYSTPSTSP 474
P +P T + P
Sbjct: 583 LQAPRRPPTPGPDTSVSGP 601
Score = 30.8 bits (68), Expect = 3.0
Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 324 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 379
+ P P +L T Q P + P +P + ++L P SP+ P P + P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 570
Query: 380 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 439
++ P +Q A ++ P V P L + P PPPPP
Sbjct: 571 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 440 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 484
P L PD ++S EGGAA+ P + PA S GP
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 676
Query: 485 DP-SFVNIPQQTQSW 498
P +F P W
Sbjct: 677 PPLAFRGAPGAPLPW 691
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 51.2 bits (121), Expect = 2e-06
Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)
Query: 176 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 235
H A + + P P A K + + +L + + + P+ A G
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332
Query: 236 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 295
+ +S + P A + P S S+T+ P + G P
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375
Query: 296 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 355
G H PG P F P PS T G QH+ P P
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421
Query: 356 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 415
P + P P+ Q P HP + P P Q G P GS
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459
Query: 416 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
QGK P P M+PPPPPPP +P P P PP + P P+ S
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518
Query: 471 STSP 474
S++P
Sbjct: 519 SSTP 522
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 51.2 bits (121), Expect = 2e-06
Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)
Query: 176 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 235
H A + + P P A K + + +L + + + P+ A G
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332
Query: 236 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 295
+ +S + P A + P S S+T+ P + G P
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375
Query: 296 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 355
G H PG P F P PS T G QH+ P P
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421
Query: 356 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 415
P + P P+ Q P HP + P P Q G P GS
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459
Query: 416 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
QGK P P M+PPPPPPP +P P P PP + P P+ S
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518
Query: 471 STSP 474
S++P
Sbjct: 519 SSTP 522
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 51.2 bits (121), Expect = 2e-06
Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)
Query: 176 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 235
H A + + P P A K + + +L + + + P+ A G
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332
Query: 236 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 295
+ +S + P A + P S S+T+ P + G P
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375
Query: 296 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 355
G H PG P F P PS T G QH+ P P
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421
Query: 356 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 415
P + P P+ Q P HP + P P Q G P GS
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459
Query: 416 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
QGK P P M+PPPPPPP +P P P PP + P P+ S
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518
Query: 471 STSP 474
S++P
Sbjct: 519 SSTP 522
Score = 35.4 bits (80), Expect = 0.12
Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 6/59 (10%)
Query: 422 PFLPTPMLPPPPPPP------MARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P LP PPPPPPP M P P P P P T G P + P P
Sbjct: 575 PPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 50.8 bits (120), Expect = 3e-06
Identities = 73/291 (25%), Positives = 101/291 (34%), Gaps = 56/291 (19%)
Query: 212 SGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPG--AMRRSLPSTSSTSS 266
+G+ S T L ++ T T S + S + SM+P ++ R LP S T
Sbjct: 257 TGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM 316
Query: 267 TKRLKSVE-DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPT-TLKKSEKSGFS 324
R + D S P R+P S + +P SPT T ++ +G
Sbjct: 317 LSRTSLTKMDSTASISRTPPRASITRTPSRASPTG-----KPSTASPTGTPSRASPTG-- 369
Query: 325 SPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP 384
SPS S G + T P T PRASP TPST P P S +I
Sbjct: 370 --SPSTASLTGLSSTAS--PTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSI---- 421
Query: 385 QETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLP 444
+ +P P P PP A P P
Sbjct: 422 -----------------------------TKMDSTASPTRTPPRASPTGTPPRASPTGTP 452
Query: 445 VPDTKPPTTSTEGGAASPT-SPTYSTPSTSPANRFVSVGPRDPSFVNIPQQ 494
+ T ST ASPT SP+ ++P+ SP+ + P S P +
Sbjct: 453 SRASPTGTQST----ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSR 499
Score = 37.4 bits (85), Expect = 0.032
Identities = 74/319 (23%), Positives = 104/319 (32%), Gaps = 28/319 (8%)
Query: 181 SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD 240
S++ PS A + P L +G S L+ GT P SL
Sbjct: 9 SRASPTRTPSTASLTGTPSRASL--------TGTPSTASLMGTPSRASLTGTPPRASLKG 60
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS 300
S + +SP R SL S+S R S+ P R+ S+
Sbjct: 61 TTSMASLMVSPS--RASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPST 118
Query: 301 GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG--PRASPHATPS 358
P S TT S S S T S A T R +T PRAS TPS
Sbjct: 119 ASLTRSPSRASLTTTP-------SRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPS 171
Query: 359 TLHFPTSPIIQQPG--PYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQ 416
T +P P P + P K +A G P S
Sbjct: 172 TASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTG-TPPRASPT 230
Query: 417 GKVHNPFLPTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 472
G P M+P PP A P + + ST +P+ P+ ++P+
Sbjct: 231 GS--PPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG 288
Query: 473 SPANRFVSVGPRDPSFVNI 491
+P+ +S+ P S + +
Sbjct: 289 TPSRASLSMTPSTASLMRM 307
Score = 37.0 bits (84), Expect = 0.042
Identities = 60/247 (24%), Positives = 84/247 (34%), Gaps = 48/247 (19%)
Query: 229 AAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGE-EPFYT 287
A+ TG + S S S S + R SL T S +S +++S +P P +T
Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWT 523
Query: 288 GQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT 347
SP +GS S+ + G PS L ++ + +PS+ S + T
Sbjct: 524 PSTASP-TGSPSTA---LAMGSPSRAALTRTPSRASLTRTPSRAS------------LTT 567
Query: 348 GPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 407
RAS TPST+ P P S + P L
Sbjct: 568 PSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSAL------------------- 608
Query: 408 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 467
L S+ P P P PP A P T P ++ G SPT
Sbjct: 609 -LTKMDSTASITRTP----PRASPTETPPRASP-------TGTPPRASPTGTPPRASPTG 656
Query: 468 STPSTSP 474
+ P SP
Sbjct: 657 TPPRASP 663
Score = 30.0 bits (66), Expect = 5.1
Identities = 49/198 (24%), Positives = 68/198 (34%), Gaps = 26/198 (13%)
Query: 180 SSQSESPS-QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAG-TGPNFS 237
S + SP+ PS A + P L +S T+ + + TP A TG
Sbjct: 478 SPSTASPTGSPSRASLTRTPSRASLTKMES--TASITRTPSRASPTWTPSTASPTG---- 531
Query: 238 LSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGS 297
S + + S S A+ R+ S T + R S P R P S S
Sbjct: 532 -SPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSAS 590
Query: 298 QSSGWHEVEP-GMPSPTTLKKSEKSGFSSPSPSQTS----------------SLGTAFTQ 340
+ P GMPS L K + + + +P + S + T
Sbjct: 591 PTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPP 650
Query: 341 HHRPVITGPRASPHATPS 358
P T PRASP TPS
Sbjct: 651 RASPTGTPPRASPTGTPS 668
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/220 (24%), Positives = 80/220 (36%), Gaps = 20/220 (9%)
Query: 249 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 308
+ P A + L + + +STK + V + P P + P + P
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832
Query: 309 MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPII 368
+P P ++S + P PS S + + Q I P P+ P P+
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-----IASQFPPPPTPPAMESQPLKPVP 887
Query: 369 QQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPM 428
P S PA++ P+ + + PD P V P P+P+
Sbjct: 888 ANVAPQ-SPPAVKAKPKWQPSS-IPVPSPD----------FPPPPPESSLVFPPPPPSPV 935
Query: 429 -LPPPPPPPMARPVP--LPVPDTKPPTTSTEGGAASPTSP 465
PPPPPPP A P P P K TS+ GG P +P
Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 46.6 bits (109), Expect = 5e-05
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 409 LNPNGSSQGKVHNPFLPT----PMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTS 464
L P S Q K+ P+ + P+ PPPPPPP P P P P P ++ G+A+P
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 465 PTYST 469
YST
Sbjct: 665 VKYST 669
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/209 (25%), Positives = 70/209 (33%), Gaps = 45/209 (21%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGP---------------RA 351
P +P+P + K + P+P+ T ++ TQ P T P
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 352 SPHATPSTLHFPTSPIIQQ------PGPYFSHPAI------RYHPQET--------LKEF 391
SP P + PT P Q P P P++ ++ P T LK
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886
Query: 392 VQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP------MLPPPPPPPMARPVPLPV 445
V P + P S V +P P P + PPPPP P+ P P P
Sbjct: 887 PANVAPQSPPAVKAKPKWQP---SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP-PP 942
Query: 446 PDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P T PT G TS T S P
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKP 971
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 12/70 (17%)
Query: 418 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPP----------TTSTEGGAASPTSPTY 467
K+H T + PP PPPP P+P P+P PP +T T + +P
Sbjct: 748 KIHQVQHITQVAPPTPPPP--PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805
Query: 468 STPSTSPANR 477
TP PA +
Sbjct: 806 PTPPVPPAKK 815
Score = 37.0 bits (84), Expect = 0.042
Identities = 53/240 (22%), Positives = 81/240 (33%), Gaps = 24/240 (10%)
Query: 237 SLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSG 296
S D S S S+ G+ S+P + S S + V D +P + +S S
Sbjct: 522 SAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDT------QPAGHVRSQSIVSS 575
Query: 297 SQSSGWHEVEPGMPSPTTLKKSEKSGFSS--PSPSQTSSLGTAFTQHH-RPVITGPRASP 353
S W S +S ++S P S + T +T P + P P
Sbjct: 576 VFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP 635
Query: 354 HATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNG 413
P P P+ Q P A + T+ +A Q +G +
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL-----QNASQHSGALFKPPTPP 690
Query: 414 SSQGKVHNPFL---PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 470
Q + P + P ++PPPPPPP P P + +P+ P +S P
Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPPP-------PPPTPGSAMAQLKPAPCAPSLPQFSAP 743
Score = 33.9 bits (76), Expect = 0.35
Identities = 50/188 (26%), Positives = 65/188 (34%), Gaps = 26/188 (13%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS- 365
P P PT +KSG S+TSS G +P T R S + S P
Sbjct: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPK 993
Query: 366 -PIIQQPGPYFSHPAIRYHP-QETLKEFVQLVCPDAGQ------------QAGQVGFLNP 411
P + F+ PA P +ETL P G+ Q G V P
Sbjct: 994 RPSVDSLVSKFTPPAESGSPSKETLPP--PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051
Query: 412 NGSSQGKVHNPFLPTPM----LPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 467
S +GK P+P PPPPP P+ +P TS + +P +
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW 1111
Query: 468 STPSTSPA 475
S S A
Sbjct: 1112 SKMSVKKA 1119
Score = 29.3 bits (64), Expect = 8.7
Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 3/75 (4%)
Query: 422 PFLPTPMLPPPPPPPM-ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
P +P P+ P PP P+ P P P T +P P PA+
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 481 VGPRDPSFVNIPQQT 495
P P V +P T
Sbjct: 827 SPPTPP--VPVPPPT 839
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 50.1 bits (118), Expect = 5e-06
Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 9/131 (6%)
Query: 349 PRASPHATPSTLHFPTSPI-IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 407
P+ +PH LH PTSP+ + P P PA + P+ + + P AG G
Sbjct: 1351 PQFAPHGR-HPLHQPTSPLPLYSPAPQHP-PAHKQGPKHFIFSHHPQMMPAAGAAGGPGS 1408
Query: 408 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTK----PPTTSTEGGAASPT 463
P G S H+P P P PP P P+P P P T PPT+ AS
Sbjct: 1409 --RPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGP 1466
Query: 464 SPTYSTPSTSP 474
T + PS +P
Sbjct: 1467 PGTANPPSANP 1477
Score = 34.7 bits (78), Expect = 0.21
Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 4/84 (4%)
Query: 400 GQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGA 459
G G +G L S +H + P PPP P +P LP P +PP G
Sbjct: 1248 GHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQP-SLPPPPQQPPPLPQLGSI 1306
Query: 460 ASPTSPTYSTPSTSPANRFVSVGP 483
P + S P P F + GP
Sbjct: 1307 PPPPA---SAPPVGPHRHFHAHGP 1327
Score = 29.3 bits (64), Expect = 8.7
Identities = 13/39 (33%), Positives = 22/39 (56%)
Query: 398 DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 436
DAG++ + + + + +G V + P +PPPPPPP
Sbjct: 1149 DAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPP 1187
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 306
+P + + P + ++ + L E +P EEP T + +P + + +
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 550
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 364
P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
S +P P P+E + P P G++ + P
Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 657
Query: 425 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 482
TP P P P P KP PTT E +P P +TP PA
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 716
Query: 483 PRDPSFVNIPQQTQ 496
P S V+ P T+
Sbjct: 717 PPTTSEVSTPTTTK 730
Score = 46.6 bits (109), Expect = 5e-05
Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 310 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 364
P+PTT K + E S ++ P+ T+ A T +P T P+ TP P
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 459
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 422
++P P P+ET + + P ++ P ++ ++ P
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 474
PTP P P P + P PTT E +P P +TP T+P
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572
Score = 46.2 bits (108), Expect = 7e-05
Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 364
P P+PTT K+ + P+P+ T S T T+ P T P +P+T P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 427
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
++P P P+E + P ++ P ++ K P
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 486
Query: 425 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
P + P P P +P P P+ PTT E +P P +TP + N
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545
Query: 481 VGPRDP 486
P P
Sbjct: 546 PAPTTP 551
Score = 46.2 bits (108), Expect = 7e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
+P + P+T + K E +P E T +G +P + + + +P
Sbjct: 539 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 310 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 362
+PTT K+ + P+P T+ GTA T P T P+ +P T P+TL
Sbjct: 597 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654
Query: 363 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 422
P ++P P P P T + P + P
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 697
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 473
P P P P P P+T PPTT ST PT SP STP S
Sbjct: 698 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749
Query: 474 PANRFVSVGPRDP 486
P + + P++P
Sbjct: 750 PTPKALENSPKEP 762
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)
Query: 256 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 315
+S P+T+ + KS +P E T + +P + + + P P+PTT
Sbjct: 394 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 447
Query: 316 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 369
K+ + P+P+ T A T P T P+ + TP L PT+P +
Sbjct: 448 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 504
Query: 370 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 429
+P P P+E + P + A PN + P P P
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 558
Query: 430 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 465
P P P + P PTT E +P P
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
+E +S ++P + + P+ + ++TK L + ++ + +EP T + +
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 238
Query: 299 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 358
S+ P P+PTT K + + P+P+ T + P T A P T S
Sbjct: 239 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 293
Query: 359 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 418
PT+P ++P P P+E + P ++ + +
Sbjct: 294 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 341
Query: 419 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P P P P P P + P PTT+ E +P P +T ++P
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)
Query: 307 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
P P+PTT K+ E + + P+ T+ A T P T P+ P T +
Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 380
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
PT+P P S P P T + + +P + +
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 430
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
P P P P P P + P PTT+ + +P P +TP + +
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490
Query: 482 GPRDP 486
P P
Sbjct: 491 TPTTP 495
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 306
+P + + P + ++ + L E +P EEP T + +P + + +
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 591
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 364
P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
S +P P P+E + P P G++ + P
Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 698
Query: 425 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 482
TP P P P P KP PTT E +P P +TP PA
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 757
Query: 483 PRDPSFVNIPQQTQ 496
P S V+ P T+
Sbjct: 758 PPTTSEVSTPTTTK 771
Score = 46.6 bits (109), Expect = 5e-05
Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 310 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 364
P+PTT K + E S ++ P+ T+ A T +P T P+ TP P
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 500
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 422
++P P P+ET + + P ++ P ++ ++ P
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 474
PTP P P P + P PTT E +P P +TP T+P
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613
Score = 46.2 bits (108), Expect = 7e-05
Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 364
P P+PTT K+ + P+P+ T S T T+ P T P +P+T P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 468
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
++P P P+E + P ++ P ++ K P
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 527
Query: 425 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
P + P P P +P P P+ PTT E +P P +TP + N
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586
Query: 481 VGPRDP 486
P P
Sbjct: 587 PAPTTP 592
Score = 46.2 bits (108), Expect = 7e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
+P + P+T + K E +P E T +G +P + + + +P
Sbjct: 580 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 310 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 362
+PTT K+ + P+P T+ GTA T P T P+ +P T P+TL
Sbjct: 638 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695
Query: 363 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 422
P ++P P P P T + P + P
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 738
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 473
P P P P P P+T PPTT ST PT SP STP S
Sbjct: 739 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790
Query: 474 PANRFVSVGPRDP 486
P + + P++P
Sbjct: 791 PTPKALENSPKEP 803
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)
Query: 256 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 315
+S P+T+ + KS +P E T + +P + + + P P+PTT
Sbjct: 435 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 488
Query: 316 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 369
K+ + P+P+ T A T P T P+ + TP L PT+P +
Sbjct: 489 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 545
Query: 370 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 429
+P P P+E + P + A PN + P P P
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 599
Query: 430 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 465
P P P + P PTT E +P P
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
+E +S ++P + + P+ + ++TK L + ++ + +EP T + +
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 279
Query: 299 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 358
S+ P P+PTT K + + P+P+ T + P T A P T S
Sbjct: 280 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 334
Query: 359 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 418
PT+P ++P P P+E + P ++ + +
Sbjct: 335 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 382
Query: 419 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P P P P P P + P PTT+ E +P P +T ++P
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)
Query: 307 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
P P+PTT K+ E + + P+ T+ A T P T P+ P T +
Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 421
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
PT+P P S P P T + + +P + +
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 471
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
P P P P P P + P PTT+ + +P P +TP + +
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531
Query: 482 GPRDP 486
P P
Sbjct: 532 TPTTP 536
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 306
+P + + P + ++ + L E +P EEP T + +P + + +
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 643
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 364
P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
S +P P P+E + P P G++ + P
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 750
Query: 425 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 482
TP P P P P KP PTT E +P P +TP PA
Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 809
Query: 483 PRDPSFVNIPQQTQ 496
P S V+ P T+
Sbjct: 810 PPTTSEVSTPTTTK 823
Score = 46.6 bits (109), Expect = 5e-05
Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 310 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 364
P+PTT K + E S ++ P+ T+ A T +P T P+ TP P
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 552
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 422
++P P P+ET + + P ++ P ++ ++ P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 474
PTP P P P + P PTT E +P P +TP T+P
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665
Score = 46.2 bits (108), Expect = 7e-05
Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 364
P P+PTT K+ + P+P+ T S T T+ P T P +P+T P
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 520
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
++P P P+E + P ++ P ++ K P
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 579
Query: 425 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
P + P P P +P P P+ PTT E +P P +TP + N
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Query: 481 VGPRDP 486
P P
Sbjct: 639 PAPTTP 644
Score = 46.2 bits (108), Expect = 7e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
+P + P+T + K E +P E T +G +P + + + +P
Sbjct: 632 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 310 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 362
+PTT K+ + P+P T+ GTA T P T P+ +P T P+TL
Sbjct: 690 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Query: 363 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 422
P ++P P P P T + P + P
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 790
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 473
P P P P P P+T PPTT ST PT SP STP S
Sbjct: 791 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842
Query: 474 PANRFVSVGPRDP 486
P + + P++P
Sbjct: 843 PTPKALENSPKEP 855
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)
Query: 256 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 315
+S P+T+ + KS +P E T + +P + + + P P+PTT
Sbjct: 487 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 540
Query: 316 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 369
K+ + P+P+ T A T P T P+ + TP L PT+P +
Sbjct: 541 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 597
Query: 370 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 429
+P P P+E + P + A PN + P P P
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 651
Query: 430 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 465
P P P + P PTT E +P P
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
+E +S ++P + + P+ + ++TK L + ++ + +EP T + +
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 299 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 358
S+ P P+PTT K + + P+P+ T + P T A P T S
Sbjct: 332 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 386
Query: 359 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 418
PT+P ++P P P+E + P ++ + +
Sbjct: 387 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 434
Query: 419 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P P P P P P + P PTT+ E +P P +T ++P
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)
Query: 307 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
P P+PTT K+ E + + P+ T+ A T P T P+ P T +
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 473
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
PT+P P S P P T + + +P + +
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 523
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
P P P P P P + P PTT+ + +P P +TP + +
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583
Query: 482 GPRDP 486
P P
Sbjct: 584 TPTTP 588
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 306
+P + + P + ++ + L E +P EEP T + +P + + +
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 684
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 364
P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
S +P P P+E + P P G++ + P
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 791
Query: 425 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 482
TP P P P P KP PTT E +P P +TP PA
Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 850
Query: 483 PRDPSFVNIPQQTQ 496
P S V+ P T+
Sbjct: 851 PPTTSEVSTPTTTK 864
Score = 46.6 bits (109), Expect = 5e-05
Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 310 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 364
P+PTT K + E S ++ P+ T+ A T +P T P+ TP P
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 593
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 422
++P P P+ET + + P ++ P ++ ++ P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 474
PTP P P P + P PTT E +P P +TP T+P
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706
Score = 46.2 bits (108), Expect = 7e-05
Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)
Query: 307 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 364
P P+PTT K+ + P+P+ T S T T+ P T P +P+T P
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 561
Query: 365 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 424
++P P P+E + P ++ P ++ K P
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 620
Query: 425 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 480
P + P P P +P P P+ PTT E +P P +TP + N
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Query: 481 VGPRDP 486
P P
Sbjct: 680 PAPTTP 685
Score = 46.2 bits (108), Expect = 7e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)
Query: 250 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 309
+P + P+T + K E +P E T +G +P + + + +P
Sbjct: 673 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 310 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 362
+PTT K+ + P+P T+ GTA T P T P+ +P T P+TL
Sbjct: 731 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Query: 363 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 422
P ++P P P P T + P + P
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 831
Query: 423 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 473
P P P P P P+T PPTT ST PT SP STP S
Sbjct: 832 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883
Query: 474 PANRFVSVGPRDP 486
P + + P++P
Sbjct: 884 PTPKALENSPKEP 896
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)
Query: 256 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 315
+S P+T+ + KS +P E T + +P + + + P P+PTT
Sbjct: 528 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 581
Query: 316 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 369
K+ + P+P+ T A T P T P+ + TP L PT+P +
Sbjct: 582 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 638
Query: 370 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 429
+P P P+E + P + A PN + P P P
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 692
Query: 430 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 465
P P P + P PTT E +P P
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 241 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 298
+E +S ++P + + P+ + ++TK L + ++ + +EP T + +
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 299 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 358
S+ P P+PTT K + + P+P+ T + P T A P T S
Sbjct: 373 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 427
Query: 359 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 418
PT+P ++P P P+E + P ++ + +
Sbjct: 428 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 475
Query: 419 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 474
P P P P P P + P PTT+ E +P P +T ++P
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)
Query: 307 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361
P P+PTT K+ E + + P+ T+ A T P T P+ P T +
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 514
Query: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421
PT+P P S P P T + + +P + +
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 564
Query: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481
P P P P P P + P PTT+ + +P P +TP + +
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624
Query: 482 GPRDP 486
P P
Sbjct: 625 TPTTP 629
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 49.3 bits (116), Expect = 8e-06
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 19/169 (11%)
Query: 292 SPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRA 351
SP S G H P +P P + S SP PS+T T HH P G +
Sbjct: 805 SPIMPPGSQGSHIHCPQLPQPALHQNSP-----SPVPSRTP------TPHHTPPSIGAQQ 853
Query: 352 SPHATPSTLHFPTSPIIQQPGPYFS--HPAIRYHPQETLKEFVQLVCPD--AGQQAGQVG 407
P AT PT P + PGP HP R P + Q V P A A Q
Sbjct: 854 PP-ATTIPAPVPTPPAMP-PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911
Query: 408 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP-VPLPVPDTKPPTTST 455
P P P+LPP P P+++P V + + PP+TS+
Sbjct: 912 -QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959
Score = 35.8 bits (81), Expect = 0.093
Identities = 50/222 (22%), Positives = 81/222 (36%), Gaps = 24/222 (10%)
Query: 283 EPFYTGQGRSPG-SGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPS--PSQTSSLGTAFT 339
+P T G P S + S +++ P + + L + + + P P QT L
Sbjct: 679 QPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPL----- 733
Query: 340 QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDA 399
QHH G A P A + + P +QQP P + + + P +
Sbjct: 734 QHH-----GQLAQPGALNPPMGY--GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSS 786
Query: 400 GQQAGQVGFLNPNGSSQGKVHNPFLPTPM------LPPPPPPPMARPVPLPVPDTKPPTT 453
GQ ++ SS V++P +P P P P + + P PVP P
Sbjct: 787 GQAPVSQAQMS---SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPH 843
Query: 454 STEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQT 495
T + P + P+ P + GP+ + P+QT
Sbjct: 844 HTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT 885
Score = 32.3 bits (72), Expect = 1.0
Identities = 54/258 (20%), Positives = 85/258 (32%), Gaps = 13/258 (5%)
Query: 227 PIAAGTGPNFSLSDLESSSYYSM-SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPF 285
P++ GPN +S + P +R S+P+ T + + S + P
Sbjct: 666 PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI 725
Query: 286 YTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 345
Q Q + + P M +++ G P +Q S G T
Sbjct: 726 VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQ-TQFPSQGMNVTNIPLAP 784
Query: 346 ITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEF----VQLVCPDAGQ 401
+G A S+ P + I PG SH PQ L + V P
Sbjct: 785 SSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHH 844
Query: 402 QAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS--TEGGA 459
+G P ++ + P P +PP P P P P PPTT +
Sbjct: 845 TPPSIGAQQPPATT---IPAPVPTPPAMPPGPQSQALHPPPRQTP--TPPTTQLPQQVQP 899
Query: 460 ASPTSPTYSTPSTSPANR 477
+ P +P+ P P ++
Sbjct: 900 SLPAAPSADQPQQQPRSQ 917
Score = 30.0 bits (66), Expect = 5.1
Identities = 27/100 (27%), Positives = 32/100 (32%), Gaps = 6/100 (6%)
Query: 401 QQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAA 460
Q+ G VG G P PT P P P P P P P AA
Sbjct: 1836 QRTGVVG--QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAA 1893
Query: 461 SPTSPTYS----TPSTSPANRFVSVGPRDPSFVNIPQQTQ 496
P S + TP T P + P+ V + Q Q
Sbjct: 1894 GPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQ 1933
Score = 29.6 bits (65), Expect = 6.7
Identities = 46/205 (22%), Positives = 68/205 (33%), Gaps = 23/205 (11%)
Query: 298 QSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 357
Q +G + G+PSPT + +G P+ QT P + P TP
Sbjct: 1836 QRTGVVGQQQGLPSPTPATPTTPTG-QQPTTPQTPQ---------------PTSQPQPTP 1879
Query: 358 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 417
P P Q GP A T + Q P A ++ +
Sbjct: 1880 PNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ 1939
Query: 418 K--VHNPFLPTPML-PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTS- 473
+ H P+ PP PMA P P T+ P+ E G PT P +
Sbjct: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPG-MGPTGMQQQPPWSQG 1998
Query: 474 --PANRFVSVGPRDPSFVNIPQQTQ 496
P + + G P+ +++ Q Q
Sbjct: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQ 2023
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,158,561
Number of Sequences: 37866
Number of extensions: 1579282
Number of successful extensions: 26016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 524
Number of HSP's successfully gapped in prelim test: 864
Number of HSP's that attempted gapping in prelim test: 11661
Number of HSP's gapped (non-prelim): 7608
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.