Search of human proteins with 217035095

Search of human proteins with 217035095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217035095 tripartite motif-containing 62 [Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217035095 tripartite motif-containing 62 [Homo sapiens]            969   0.0  
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   253   3e-67
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   247   2e-65
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   236   3e-62
gi|30023818 tripartite motif protein 50A [Homo sapiens]               219   4e-57
gi|5730009 ret finger protein [Homo sapiens]                          214   2e-55
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            211   9e-55
gi|15208660 tripartite motif protein 21 [Homo sapiens]                206   5e-53
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             204   1e-52
gi|37622899 ring finger protein 137 [Homo sapiens]                    203   2e-52
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    197   1e-50
gi|56605981 tripartite motif-containing 72 [Homo sapiens]             196   4e-50
gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   187   2e-47
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             187   2e-47
gi|22749269 ring finger protein 129 [Homo sapiens]                    186   5e-47
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    185   9e-47
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    185   9e-47
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              180   3e-45
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]   176   5e-44
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            172   8e-43
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   169   7e-42
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    169   7e-42
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   166   6e-41
gi|63054855 erythroblast membrane-associated protein precursor [...   160   2e-39
gi|19923536 erythroblast membrane-associated protein precursor [...   160   2e-39
gi|149193331 tripartite motif protein 15 [Homo sapiens]               152   8e-37
gi|4557743 Mediterranean fever protein [Homo sapiens]                 149   4e-36
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   147   3e-35
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      146   5e-35
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      146   5e-35

>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  969 bits (2504), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEP 60
           MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEP
Sbjct: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEP 60

Query: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALH 120
           ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALH
Sbjct: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALH 120

Query: 121 EQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGE 180
           EQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGE
Sbjct: 121 EQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGE 180

Query: 181 AFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETD 240
           AFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETD
Sbjct: 181 AFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETD 240

Query: 241 RHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLD 300
           RHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLD
Sbjct: 241 RHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLD 300

Query: 301 PGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEK 360
           PGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEK
Sbjct: 301 PGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEK 360

Query: 361 TQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFL 420
           TQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFL
Sbjct: 361 TQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFL 420

Query: 421 DYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI 475
           DYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI
Sbjct: 421 DYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI 475


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  253 bits (645), Expect = 3e-67
 Identities = 152/468 (32%), Positives = 237/468 (50%), Gaps = 9/468 (1%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63
           +L+ E  CS+CL   ++PV + C H FC+ CIT  W  ++ +    CP CR+T    +L 
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW--EDLERDFPCPVCRKTSRYRSLR 79

Query: 64  PSLKLANIVERYSSFPLDAILNARRAARPC-QAHDKVKLFCLTDRALLCFFCDEPALHEQ 122
           P+ +L ++VE      L A+    R    C Q H+ + LFC  D+  +C  C     H  
Sbjct: 80  PNRQLGSMVEIAKQ--LQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRA 137

Query: 123 HQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAF 182
           H V  +DDA  E + +L+  L+ L+   +E T      +++  E K   +S R  I   F
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 183 ERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRH 242
           E LHR L E Q+ +L  LE +    L  + +       + R +   A  ++ +  ++   
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFE 257

Query: 243 TFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPG 302
                 ++L +  K K  E      +   +    P QY   + + + +    A +TLDP 
Sbjct: 258 MLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI---ADVTLDPE 314

Query: 303 TAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQ 362
           TAH  L+LS+D   V +     + L D+P+RF     VL +E F+SG HYWEV V +KT 
Sbjct: 315 TAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTH 374

Query: 363 WVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDY 422
           W +G+  ++ SRKG +   P  G++ + + +G++Y+A T P+T L+++ K  +VG+FLDY
Sbjct: 375 WAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDY 434

Query: 423 DQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           + G L FYN  D S +YTF + F  KL   F PG   A  KN  PL I
Sbjct: 435 EAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPG-IRAGRKNAAPLTI 481


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  247 bits (630), Expect = 2e-65
 Identities = 160/499 (32%), Positives = 246/499 (49%), Gaps = 41/499 (8%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63
           +L+ E  CS+CL   ++PV + C H FC+ CIT  W  ++ +    CP CR+T    +L 
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW--EDLERDFPCPVCRKTSRYRSLR 79

Query: 64  PSLKLANIVERYSSFPLDAILNARRAARPC-QAHDKVKLFCLTDRALLCFFCDEPALHEQ 122
           P+ +L ++VE      L A+    R    C Q H+ + LFC  D+  +C  C     H  
Sbjct: 80  PNRQLGSMVEIAKQ--LQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRA 137

Query: 123 HQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAF 182
           H V  +DDA  E + +L+  L+ L+   +E T      +++  E K   +S R  I   F
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 183 ERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKV------------QEGAQ 230
           E LHR L E Q+ +L  LE +    L  + +       + R +            Q G +
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFE 257

Query: 231 ILQERLAETDRHTFLAGVASLS-------ERLKGKIHETNLTYEDFPTSKYTG------- 276
           +L++  +  +++       SLS       + L G + E N   E   T + T        
Sbjct: 258 MLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRC-EKVKTMEVTSVSIELEK 316

Query: 277 -----PLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSP 331
                P QY   + + + +    A +TLDP TAH  L+LS+D   V +     + L D+P
Sbjct: 317 NFSNFPRQYFALRKILKQLI---ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTP 373

Query: 332 KRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVM 391
           +RF     VL +E F+SG HYWEV V +KT W +G+  ++ SRKG +   P  G++ + +
Sbjct: 374 RRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRL 433

Query: 392 HDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCS 451
            +G++Y+A T P+T L+++ K  +VG+FLDY+ G L FYN  D S +YTF + F  KL  
Sbjct: 434 WNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWP 493

Query: 452 YFSPGQSHANGKNVQPLRI 470
            F PG   A  KN  PL I
Sbjct: 494 LFYPG-IRAGRKNAAPLTI 511


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  236 bits (602), Expect = 3e-62
 Identities = 149/469 (31%), Positives = 232/469 (49%), Gaps = 16/469 (3%)

Query: 8   ELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLK 67
           EL C +C   ++DP+ L C H FC  CI + W  Q  +    CPEC+          +  
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF--CPECKMLCQYNNCTFNPV 95

Query: 68  LANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALH--EQHQ 124
           L  +VE+    PL       +    C  H + +KLF   D  L+CF C +  L   +  +
Sbjct: 96  LDKLVEKIKKLPL------LKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKE 149

Query: 125 VTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFER 184
              I DA      EL  Q   L+ + +E      + K  +A  K +   L+  +   F +
Sbjct: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLK 209

Query: 185 LHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTF 244
           LH+ L  ++K +L EL  +      ++E  + +  +Q    ++    +Q +  + +   F
Sbjct: 210 LHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDF 269

Query: 245 LAGVASLSERLKG--KIHETN-LTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDP 301
           L  + +L   L+   K+  T  L        +Y GP+QY +W+ +   + P  + LTLDP
Sbjct: 270 LKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDP 329

Query: 302 GTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKT 361
            TAH  L+LS   T V +G++  + + D P+RFD  V+VLGS  F+SG  YWEV VA+KT
Sbjct: 330 KTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 388

Query: 362 QWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLD 421
           +W +G+  E+  RKGS  + P +GF+ + + +     A   P   L + + LDKVG++LD
Sbjct: 389 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLD 448

Query: 422 YDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           Y+ G L FYNA  M+ +YTF   F  KL  YF P  +   G+N +PL I
Sbjct: 449 YEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLND-GGENKEPLHI 496


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  219 bits (558), Expect = 4e-57
 Identities = 140/471 (29%), Positives = 222/471 (47%), Gaps = 19/471 (4%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAP 64
           L+D L C ICL ++++P+ L C H +C+ C+       +A+    CP CR+     +  P
Sbjct: 10  LEDWLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAE--LRCPVCRQAVDGSSSLP 67

Query: 65  SLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQH 123
           ++ LA ++E          L      + C  H + + LFC  D+ L+C  C     H+ H
Sbjct: 68  NVSLARVIEALR-------LPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120

Query: 124 QVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183
            VT +   +  ++ EL   +  L+  +++  E +  L        + +      I   F+
Sbjct: 121 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 180

Query: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243
            LH L+ E +   LE +   T   +  ++ ++++ +Q  R+    A+ + E+    D H 
Sbjct: 181 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQ-AQGTRERLAQAECVLEQFGNEDHHK 239

Query: 244 FLA---GVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLD 300
           F+     +AS +E  + +  E   +   F    +   ++ T+WK LF+ + P P  L LD
Sbjct: 240 FIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLD 299

Query: 301 PGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEK 360
           P TAH  L LS   T+V  G L  Q     P+RFD    VL S  FS G HYWEVVV  K
Sbjct: 300 PATAHPLLELSKGNTVVQCGLL-AQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSK 358

Query: 361 TQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFL 420
           + W +G+    ASRKG +   P  G + I + +G  Y A   P   L V     ++G++L
Sbjct: 359 SDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYL 418

Query: 421 DYDQGLLIFYNA---DDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPL 468
            Y+QG L F++A   DD+  LYTF+  F GKL         H  G N  P+
Sbjct: 419 HYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCW-HERGSNSLPM 468


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  214 bits (544), Expect = 2e-55
 Identities = 142/485 (29%), Positives = 227/485 (46%), Gaps = 24/485 (4%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAP 64
           L+ E  C +CL  + +P+ L C H  C  C+   W   E   +  CP+CR TF +  + P
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVS--CPQCRETFPQRHMRP 67

Query: 65  SLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQH 123
           +  LAN+ +       +           C+ H + +KL+C  D+  +C  CD    H  H
Sbjct: 68  NRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGH 127

Query: 124 QVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183
            V  +++A +  + ++++QL  L+  +          ++  AE  S T+  R  I   FE
Sbjct: 128 SVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFE 187

Query: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243
           +L+  L+E +  +L  LE         I   + ++S  +  +      L+E+  +  R  
Sbjct: 188 QLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTREL 247

Query: 244 FLAGVASLSERLKGKIHETNLTYEDFPTS----------------KYTGPLQYTIWK-SL 286
                 +LS   + +I E  +T  D                    ++T  +Q  + K   
Sbjct: 248 LQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQE 307

Query: 287 FQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAF 346
            ++       +TLDP TA+  LILSD+   V Y  L  Q L D+P+RF++   VLGS  F
Sbjct: 308 LREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQ-QDLPDNPERFNLFPCVLGSPCF 366

Query: 347 SSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTR 406
            +G HYWEV V +K +W IG+  ++  RKG +   P  GF+ + +  G +Y A T P T 
Sbjct: 367 IAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTA 426

Query: 407 LNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTF-REKFPGKLCSYFSPGQSHANGKNV 465
           L +R  L +VG+FLDYD G + FYN  +    +TF    F G +  YFS   S++ GK+ 
Sbjct: 427 LPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFS--LSYSGGKSA 484

Query: 466 QPLRI 470
            PL I
Sbjct: 485 APLII 489


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  211 bits (538), Expect = 9e-55
 Identities = 141/457 (30%), Positives = 213/457 (46%), Gaps = 26/457 (5%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQ--GARDCPECRRTFAEPAL 62
           L+++  C +CL   Q+PVS+ C H FC RCI+E   + +    G   CP+CR  F     
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 63  APSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQ 122
            P+ +LA +VE      L A   ARR AR     + +  FC  D A LC+ CD    H  
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARRCARH---GEDLSRFCEEDEAALCWVCDAGPEHRT 126

Query: 123 HQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAF 182
           H+   + +A    Q +L+  L+ ++    +       + ++    K   +  R      F
Sbjct: 127 HRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEF 186

Query: 183 ERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRH 242
           E+    L + ++  L  LEA+   TL  + +   R  QQ + ++E A  LQER  +    
Sbjct: 187 EKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQER-CQRPAL 245

Query: 243 TFLAGVASLSERLKGKIHETNLTYEDFPTSKYTG---PLQYTIWKSLFQDIHPVPAALTL 299
             L GV  +  R K     T L  E+ P    T    P +  + +    D+        L
Sbjct: 246 GLLEGVRGVLSRSKAV---TRLEAENIPMELKTACCIPGRRELLRKFQVDVK-------L 295

Query: 300 DPGTAHQRLILSDDCTIVAYGNLHPQPLQD---SPKRFDVEVSVLGSEAFSSGVHYWEVV 356
           DP TAH  L+L+ D   V  G    +P +D   +P+RFD    +LG ++FSSG HYWEV+
Sbjct: 296 DPATAHPSLLLTADLRSVQDG----EPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVL 351

Query: 357 VAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKV 416
           V E  +W +G+  +   RKG     P  G + + +  GN+Y     P   L   +    +
Sbjct: 352 VGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCI 411

Query: 417 GVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYF 453
           G+FLDY+ G + FYN  D S++YTF + F G L  YF
Sbjct: 412 GIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYF 448


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  206 bits (523), Expect = 5e-53
 Identities = 148/476 (31%), Positives = 233/476 (48%), Gaps = 27/476 (5%)

Query: 7   DELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSL 66
           +E+ C ICL  + +PVS+ C H FC+ CI++        G   CP CR+ F    L P+ 
Sbjct: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQ----VGKGGGSVCPVCRQRFLLKNLRPNR 67

Query: 67  KLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQHQV 125
           +LAN+V        +A    +     C  H +++ LFC  D   LC+ C +   H  H +
Sbjct: 68  QLANMVNNLKEISQEAREGTQ--GERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125

Query: 126 TGIDDAFDELQRELKDQLQALQDSER--EHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183
             +++A  E Q +L+  L  L+  +   E  E    +KR  A+ K + ++ ++ I   F 
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKR--ADWKKTVETQKSRIHAEFV 183

Query: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243
           +    L E ++  L+ELE D    L  + +K  + +QQ       +Q LQE ++E DR  
Sbjct: 184 QQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQ-------SQALQELISELDRRC 236

Query: 244 FLAGVASLSERL--KGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDP 301
             + +  L E +    +    NL   D  + +          K +   +      +TLDP
Sbjct: 237 HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKM---LRTCAVHITLDP 293

Query: 302 GTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKT 361
            TA+  LILS+D   V  G+   Q +  + +RFD    VLG++ F SG HYWEV V  K 
Sbjct: 294 DTANPWLILSEDRRQVRLGDTQ-QSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKE 352

Query: 362 QWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLD 421
            W +G+  ++  RKG   +    GF+ I + +  +Y A T P T L+++    +VG+FLD
Sbjct: 353 AWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLD 412

Query: 422 YDQGLLIFYN-ADDMSWLYTFRE-KFPGKLCSYFSPGQSHANGKNVQPLRINTVRI 475
           Y+ G++ FYN  D  S +Y+F E  F G L  +FSPG  +  GKN  PL +  + I
Sbjct: 413 YEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPG-FNDGGKNTAPLTLCPLNI 467


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  204 bits (520), Expect = 1e-52
 Identities = 154/471 (32%), Positives = 226/471 (47%), Gaps = 48/471 (10%)

Query: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEP 60
           ++ +L++E  C+ICL  + DPV   C H FCR CI   W + E  G   CPECR    + 
Sbjct: 6   LSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPE--GPYACPECRELSPQR 63

Query: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARP-------CQAH-DKVKLFCLTDRALLCF 112
            L P+  LA + E            ARR   P       C AH + +  FC  +  LLC 
Sbjct: 64  NLRPNRPLAKMAEM-----------ARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCA 112

Query: 113 FCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAET----K 168
            C+    H  H+V  + DA ++L+ +L+  L+ L    R+  +   L + Q  ET    +
Sbjct: 113 ACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHL----RKQMQDALLFQAQADETCVLWQ 168

Query: 169 SSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEG 228
              +S R  +   FERL RLL E ++ +L+ LE +    L  + +      QQ       
Sbjct: 169 KMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQ------- 221

Query: 229 AQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQY-TIWK--S 285
           +  L E +AE +    L  +  L + +K  +          P      P++  T+ +   
Sbjct: 222 SAHLAELIAELEGRCQLPALGLLQD-IKDALRRVQDVKLQPPE---VVPMELRTVCRVPG 277

Query: 286 LFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEA 345
           L + +      +TLDP TA+  LILS+D   V  G+L  Q L DSP+RFD    VLG E 
Sbjct: 278 LVETLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLR-QALPDSPERFDPGPCVLGQER 336

Query: 346 FSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWT 405
           F+SG HYWEV V ++T W +G+  E  +RK   ++    GF+ +V   G+ Y++      
Sbjct: 337 FTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFL-GSYYNSSERALA 395

Query: 406 RLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFRE-KFPGKLCSYFSP 455
            L  RD   +VG+FLDY+ G L FY+A D S L+ F E  F G L   FSP
Sbjct: 396 PL--RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSP 444


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  203 bits (517), Expect = 2e-52
 Identities = 145/483 (30%), Positives = 244/483 (50%), Gaps = 29/483 (6%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHW-VRQEAQG-ARDCPECRRTFAEPA 61
           ++ +E+ C IC++  ++P+S+ C H FC  C++  W +  E+Q     CP CR       
Sbjct: 9   AIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRN 68

Query: 62  LAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALH 120
           L P+ +LAN+VE+     L   +  +     C+ H +K+K+FC  D  ++C  C +   H
Sbjct: 69  LRPNWQLANVVEKVRLLRLHPGMGLKGDL--CERHGEKLKMFCKEDVLIMCEACSQSPEH 126

Query: 121 EQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGE 180
           E H V  ++D   E + EL + L+ L+  + E  +     +++ A  K   ++ + +I  
Sbjct: 127 EAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVW 186

Query: 181 AFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLR----KVQEGAQILQERL 236
            FE+  RLL ++Q     +L A+ A  L  ++++     Q+L     ++ + +Q+L   +
Sbjct: 187 EFEKYQRLLEKKQPPH-RQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMI 245

Query: 237 AETDRHT------FLAGVASLSERLKG-KIHETNLTYEDFPTSKYTGPLQYTIWKSLFQD 289
           AE    +       L  +  +  R K   + +      +  T      L+  I K+   D
Sbjct: 246 AELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLR-EILKTYAAD 304

Query: 290 IHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSG 349
           +        LDP TA+ RLI+S+D   V YG+ + Q L D+P+RF     VLGS+  SSG
Sbjct: 305 VR-------LDPDTAYSRLIVSEDRKRVHYGDTN-QKLPDNPERFYRYNIVLGSQCISSG 356

Query: 350 VHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNV 409
            HYWEV V ++++W +G+  +   RK  + + P  GF+ I +  GN+Y A T+ +  L++
Sbjct: 357 RHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSL 416

Query: 410 RDKLDKVGVFLDYDQGLLIFYNADDM-SWLYTF-REKFPGKLCSYFSPGQSHANGKNVQP 467
                +VG+F+DY+   + FYN  D  S ++TF R  FPG+L  YFSP  S     N  P
Sbjct: 417 PVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYS-IGTNNTAP 475

Query: 468 LRI 470
           L I
Sbjct: 476 LAI 478


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  197 bits (502), Expect = 1e-50
 Identities = 157/496 (31%), Positives = 226/496 (45%), Gaps = 57/496 (11%)

Query: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGAR----------DC 50
           +A  L+ E  CSICL ++++PVS+ C H FCR CI   W R  A               C
Sbjct: 19  LAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPC 78

Query: 51  PECRRTFAEPALAPSLKLANIVERYSSFPLDAILN---------ARRAARPCQAH-DKVK 100
           P+CR       L P+ +LA +      F L A            AR AA  C  H +  K
Sbjct: 79  PQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFK 138

Query: 101 LFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQAL----QDSE----RE 152
           L+C  D   +C  CD    H +H V  +D+A  E +  L+ +L+ L    +D E     E
Sbjct: 139 LYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTE 198

Query: 153 HTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAML---EELEADTAR--- 206
             E+ +LLK+  AE +         +G  F+ L   L E++  +L   EEL  + A+   
Sbjct: 199 KKESKELLKQMAAEQEK--------VGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQN 250

Query: 207 -TLTDIEQKVQRYSQQLRKVQEGAQ-----ILQERLAETDRHTFLAGV--ASLSERLKGK 258
             L  +  ++ + S+   ++QE AQ      LQE  +   R + + G    ++S  +K K
Sbjct: 251 ENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNK 310

Query: 259 IHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVA 318
           +   N++ + F         +  +   L ++       LTLDP TA+ RLILS D   V 
Sbjct: 311 VW--NVSLKTFVLKGMLKKFKEDLRGELEKE---EKVELTLDPDTANPRLILSLDLKGVR 365

Query: 319 YGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSI 378
            G    Q L + P RFD    VL S  FSSG H+WEV V  K  W  G+A E+  RKG  
Sbjct: 366 LGE-RAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLT 424

Query: 379 QIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWL 438
              P  G + + + +G QY A T P         L +V V LD + G + FY  +DM  L
Sbjct: 425 PFTPEEGVWALQL-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHL 483

Query: 439 YTFREKFPGKLCSYFS 454
           YTFR  F  ++   FS
Sbjct: 484 YTFRVNFQERVFPLFS 499


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score =  196 bits (498), Expect = 4e-50
 Identities = 124/472 (26%), Positives = 223/472 (47%), Gaps = 20/472 (4%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAP 64
           L  EL C +CL ++  PV+  C H FCR C+        A G   CP C+      AL+ 
Sbjct: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67

Query: 65  SLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQH 123
           +L+LA +VE  +  P             C+ H D + ++C  DRAL+C  C     H  H
Sbjct: 68  NLQLARLVEGLAQVPQGH----------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117

Query: 124 QVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183
           ++    +A   L+ +L  Q   LQ++     +++ +L+ QL E + + +  R  +GE   
Sbjct: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLG 177

Query: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243
           ++   L   + ++  E E         + +++   +  L ++++  ++L+E +A+  +  
Sbjct: 178 KMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEE-VADKPQTE 236

Query: 244 FLAGVASLSERLKGKIHETNLTYE-DFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPG 302
           FL     ++ RL+  + E+      D      +   ++ +W+ +F+ + P    LT DP 
Sbjct: 237 FLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPS 296

Query: 303 TAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQ 362
           +AH  L++S     V        P  + P++FD  V+V+  +  S G HYWEV V +K +
Sbjct: 297 SAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPR 356

Query: 363 WVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSA---CTEPWTRLNVRDKLDKVGVF 419
           W +G+    A R+G +   PS+G + + + +G    A     EP    +   +  ++G++
Sbjct: 357 WALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLY 416

Query: 420 LDYDQGLLIFYNADD---MSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPL 468
           L +  G+L FY+A D   +  L+ F E+ P  +  +F     H  GKN QPL
Sbjct: 417 LSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCW-HDKGKNAQPL 467


>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  187 bits (474), Expect = 2e-47
 Identities = 111/339 (32%), Positives = 179/339 (52%), Gaps = 5/339 (1%)

Query: 135 LQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQK 194
           ++ EL  Q   L+ + +E      + K  +A  K +   L+  +   F +LH+ L  ++K
Sbjct: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK 60

Query: 195 AMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSER 254
            +L EL  +      ++E  + +  +Q    ++    +Q +  + +   FL  + +L   
Sbjct: 61  DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS 120

Query: 255 LKG--KIHETN-LTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILS 311
           L+   K+  T  L        +Y GP+QY +W+ +   + P  + LTLDP TAH  L+LS
Sbjct: 121 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS 180

Query: 312 DDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEA 371
              T V +G++  + + D P+RFD  V+VLGS  F+SG  YWEV VA+KT+W +G+  E+
Sbjct: 181 KSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRES 239

Query: 372 ASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYN 431
             RKGS  + P +GF+ + + +     A   P   L + + LDKVG++LDY+ G L FYN
Sbjct: 240 IIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYN 299

Query: 432 ADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           A  M+ +YTF   F  KL  YF P  +   G+N +PL I
Sbjct: 300 AKTMTHIYTFSNTFMEKLYPYFCPCLND-GGENKEPLHI 337


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  187 bits (474), Expect = 2e-47
 Identities = 130/469 (27%), Positives = 218/469 (46%), Gaps = 18/469 (3%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63
           +L++EL C ICL  +  PV+  C H FC  C+   W  +E      CPEC RT   P   
Sbjct: 9   NLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSW--EEHNTPLSCPECWRTLEGPHFQ 66

Query: 64  PSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQH 123
            + +L  +           + +        +     K     ++    F       H  +
Sbjct: 67  SNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQS---HGAN 123

Query: 124 QVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183
           +V    +A +  + +L++ L  L+   +E    L   K ++   +  TK+ +  +   + 
Sbjct: 124 RVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYM 183

Query: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243
           ++H+ L+E ++  L+ LE +    +  +     + +QQ+R        L + +A+ +  +
Sbjct: 184 KMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRS-------LSKMIAQIESSS 236

Query: 244 FLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGT 303
             +   SL E ++G +  +       P +  T  L       + + +      +TLDP T
Sbjct: 237 QSSAFESLEE-VRGALERSEPLLLQCPEATTT-ELSLCRITGMKEMLRKFSTEITLDPAT 294

Query: 304 AHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQW 363
           A+  L+LS+D   V YG    Q L D+P+RFD   +VLG++ F+SG HYWEV V  KT+W
Sbjct: 295 ANAYLVLSEDLKSVKYGGSRQQ-LPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEW 353

Query: 364 VIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSA-CTEPWTRLNVRDKLDKVGVFLDY 422
            +G+  ++ SRKG++   P   F  I +  G+ YS   + P    +VR+ + KVGVFLDY
Sbjct: 354 EVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDY 413

Query: 423 DQGLLIFYNADDMSWLYTF-REKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           + G + FYN  D S +Y+F +  F   L   FSP   +  G N  PL I
Sbjct: 414 ESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPN-EGTNTDPLTI 461


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  186 bits (471), Expect = 5e-47
 Identities = 135/477 (28%), Positives = 224/477 (46%), Gaps = 26/477 (5%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63
           +L++E  C ICL   +DPV++ C H FCR C++  W  ++      CP CR  F   +  
Sbjct: 9   NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSW--KDLDDTFPCPVCRFCFPYKSFR 66

Query: 64  PSLKLANIVERYSSFPLDAILNARRAARP-CQAHDK-VKLFCLTDRALLCFFCDEPALHE 121
            + +L N+ E      +      R+     C+ H++ + LFC+ D  +LC  C     H+
Sbjct: 67  RNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQ 126

Query: 122 QHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA 181
           +H +  I  A    +  L+  L+ L+++     + + L   +  E K   +  R  I   
Sbjct: 127 KHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSE 186

Query: 182 FERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDR 241
           FE++   L+  Q+ +L +++ +    L  +       ++ L ++ +    L+  L E + 
Sbjct: 187 FEQIRLFLQNEQEMILRQIQDEEMNILAKL-------NENLVELSDYVSTLKHLLREVEG 239

Query: 242 HTFLAGVASLSERLKGKIHETNLTYED---FPTSKY--TGPLQYTIWKSLFQDIHPVPAA 296
            +  + +  L++         NL   +   F  +KY  + P QY+    L + I P    
Sbjct: 240 KSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYS---GLDRIIKPFQVD 296

Query: 297 LTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVV 356
           + LD  TAH +L++S+D   V Y         D P+RF V  +VLGS+ FSSG HYWEV 
Sbjct: 297 VILDLNTAHPQLLVSEDRKAVRYERKKRNICYD-PRRFYVCPAVLGSQRFSSGRHYWEVE 355

Query: 357 VAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKV 416
           V  K +W++G+  +   R    Q     GF+ I  +  + Y A     T+L    K  K+
Sbjct: 356 VGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKI 415

Query: 417 GVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTV 473
           G+FLDY+ G L FYN +D S LYTF + F   +  YF        G + +PL+I +V
Sbjct: 416 GIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYF------YTGTDSEPLKICSV 466


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  185 bits (469), Expect = 9e-47
 Identities = 139/477 (29%), Positives = 229/477 (48%), Gaps = 37/477 (7%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCIT----EHWVRQEAQGARDCPECRRTFAEP 60
           +++E+ C ICL +  +P+S+ C H FC+ CIT    E  + QE  G R CP C+ ++   
Sbjct: 9   IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE--GERSCPVCQTSYQPG 66

Query: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPAL 119
            L P+  LANIV R     L      +  A  C  H +K++LFC  D  ++C+ C+    
Sbjct: 67  NLRPNRHLANIVRRLREVVLGP--GKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 124

Query: 120 HEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179
           H  H    +++   E Q + ++ L+ L++ E+E  +    ++ +    K+  +  R  I 
Sbjct: 125 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 184

Query: 180 EAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAET 239
             F +L  +L   ++  L++LE +  + L  IE+       Q + ++E    L ER  + 
Sbjct: 185 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL-ERRCQG 243

Query: 240 DRHTFLAGVASLSERLKGKIHETNLTYEDFPT---SKYTGP---LQYTIWKSLFQDIHPV 293
                L  V+ ++ER +     T    E  PT   S +  P       + + L  D+   
Sbjct: 244 STMELLQDVSDVTERSE---FWTLRKPEALPTKLRSMFRAPDLKRMLRVCREL-TDVQSY 299

Query: 294 PAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYW 353
              +TL+P TA+  L+L+ +   V +            K +D   SVLGS+ FSSG HYW
Sbjct: 300 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD--CSVLGSQHFSSGKHYW 357

Query: 354 EVVVAEKTQWVIGLA-----------HEAASRKGSIQIQPSRGFYCIVMHDGNQYSAC-- 400
           EV VA+KT W++G+            H A +     + QP  G++ I +   ++Y A   
Sbjct: 358 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 417

Query: 401 TEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSW-LYTF-REKFPGKLCSYFSP 455
           + P   L++     +VGVFLDY+ G + FYN  +  + +YTF +  FP  LC YF+P
Sbjct: 418 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  185 bits (469), Expect = 9e-47
 Identities = 139/477 (29%), Positives = 229/477 (48%), Gaps = 37/477 (7%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCIT----EHWVRQEAQGARDCPECRRTFAEP 60
           +++E+ C ICL +  +P+S+ C H FC+ CIT    E  + QE  G R CP C+ ++   
Sbjct: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE--GERSCPVCQTSYQPG 94

Query: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPAL 119
            L P+  LANIV R     L      +  A  C  H +K++LFC  D  ++C+ C+    
Sbjct: 95  NLRPNRHLANIVRRLREVVLGP--GKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152

Query: 120 HEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179
           H  H    +++   E Q + ++ L+ L++ E+E  +    ++ +    K+  +  R  I 
Sbjct: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212

Query: 180 EAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAET 239
             F +L  +L   ++  L++LE +  + L  IE+       Q + ++E    L ER  + 
Sbjct: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL-ERRCQG 271

Query: 240 DRHTFLAGVASLSERLKGKIHETNLTYEDFPT---SKYTGP---LQYTIWKSLFQDIHPV 293
                L  V+ ++ER +     T    E  PT   S +  P       + + L  D+   
Sbjct: 272 STMELLQDVSDVTERSE---FWTLRKPEALPTKLRSMFRAPDLKRMLRVCREL-TDVQSY 327

Query: 294 PAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYW 353
              +TL+P TA+  L+L+ +   V +            K +D   SVLGS+ FSSG HYW
Sbjct: 328 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD--CSVLGSQHFSSGKHYW 385

Query: 354 EVVVAEKTQWVIGLA-----------HEAASRKGSIQIQPSRGFYCIVMHDGNQYSAC-- 400
           EV VA+KT W++G+            H A +     + QP  G++ I +   ++Y A   
Sbjct: 386 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 445

Query: 401 TEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSW-LYTF-REKFPGKLCSYFSP 455
           + P   L++     +VGVFLDY+ G + FYN  +  + +YTF +  FP  LC YF+P
Sbjct: 446 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 502


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  180 bits (456), Expect = 3e-45
 Identities = 137/467 (29%), Positives = 216/467 (46%), Gaps = 44/467 (9%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARD----CPECRRTFAEP 60
           + +E  CSICLS+  +PVS+ C H +C  CIT+ +     +  R     CP+CR  F   
Sbjct: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69

Query: 61  ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPAL 119
           +L P+ +L +++E          L        C+ H ++  LFC  +  L+C+ C+    
Sbjct: 70  SLRPNKQLGSLIEA---------LKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ 120

Query: 120 HEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179
           H+ H    ++D     + +L+  +  L+  E   TE       ++ + K   +  R  I 
Sbjct: 121 HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR 180

Query: 180 EAFERLHRLLRERQKAMLEELEADTARTLT---DIEQKVQRYSQQLR--------KVQEG 228
             F+ L   L E +K+ L  LE +  +TL+   D E  +   S +L+        K Q  
Sbjct: 181 SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS 240

Query: 229 AQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQ 288
           AQ L + + +T           LS     K+  +     +  T      L + + K L  
Sbjct: 241 AQKLLQNVNDT-----------LSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRS 289

Query: 289 DIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQD-SPKRFDVEVSVLGSEAFS 347
             H V  ++TLDP TAH  LILS+D   V  G  + Q  QD S +RF     VLG E F+
Sbjct: 290 --HQV--SVTLDPDTAHHELILSEDRRQVTRG--YTQENQDTSSRRFTAFPCVLGCEGFT 343

Query: 348 SGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRL 407
           SG  Y+EV V E T W +G+  E   R   ++ +P  GF+ + +     Y A T P T L
Sbjct: 344 SGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSL 403

Query: 408 NVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTF-REKFPGKLCSYF 453
           ++ ++   VG+FLDY+ G++ FYN +    ++TF +  F   L  YF
Sbjct: 404 HLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450


>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
          Length = 493

 Score =  176 bits (445), Expect = 5e-44
 Identities = 133/489 (27%), Positives = 221/489 (45%), Gaps = 34/489 (6%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63
           S K+ELLC++C   ++D V+L C H FCR C++  W   E Q +  CP C+   +   L 
Sbjct: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW---EVQVSPTCPVCKDRASPADLR 70

Query: 64  PSLKLANIVERYSSFPLD-AILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHE 121
            +  L N+VE+      + A   + R +R C+ H  ++ LFCL D+ LLC  C     H+
Sbjct: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130

Query: 122 QHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA 181
            H+V  + D   + + + ++   AL++  +      +  +      +     L   I + 
Sbjct: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190

Query: 182 FERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDR 241
           F++L   LR  ++A+L+ +  +T +     ++K+++ +++   +    + LQ  + E D 
Sbjct: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDD- 249

Query: 242 HTFLAGVASLSERLKGKIHETNLTYEDFPTS--------KYTGPLQYTIWKSLFQDIHPV 293
                   S   + K +      T E  P          KY G LQY +WK +   +  V
Sbjct: 250 -------VSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV 302

Query: 294 PAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYW 353
           P   + DP TA   L +SDD T V       Q   ++P+RF     +LGS  FS G H W
Sbjct: 303 P--FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAW 358

Query: 354 EVVVAEKTQWVIGLAH-----EAASRKGSIQIQPSRGFYCIVMHDGNQYSAC--TEPWTR 406
           EV +     W +G+        A     S       GF+ +    G +   C  ++P T 
Sbjct: 359 EVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418

Query: 407 LNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQ 466
             V     ++ V L+ ++G L FY+A+    LYTF  +F G++  YF  G +   G   +
Sbjct: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYLGGARGAGP-PE 476

Query: 467 PLRINTVRI 475
           PLRI  + I
Sbjct: 477 PLRICPLHI 485


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  172 bits (435), Expect = 8e-43
 Identities = 133/478 (27%), Positives = 214/478 (44%), Gaps = 34/478 (7%)

Query: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAP 64
           L+ E  CSICL    DPV++ C H FCR CI + W+  + Q    CP CR    E     
Sbjct: 10  LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWL--DLQELFPCPVCRHQCQEGHFRS 67

Query: 65  SLKLANIVERYSSFPLDAILNARRAARP--CQAHDK-VKLFCLTDRALLCFFCDEPALHE 121
           + +L  ++E  +        N R+      C+ H++ + +FC  D  +LC  C +P  H+
Sbjct: 68  NTQLGRMIE-IAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQ 126

Query: 122 QHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA 181
            H V  I+ A    ++     +Q L+    +  + +    ++  E +   ++ R  +   
Sbjct: 127 GHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSSE 186

Query: 182 FERLHRLLRERQKAMLEEL---EADTARTLTDIEQKVQRYS----QQLRKVQEGAQILQE 234
           FE L++ L   Q+A+L  L   E D  + L+        YS     QL KV E +++ + 
Sbjct: 187 FEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSEL 246

Query: 235 RLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVP 294
            L    +  + +   S        +     ++          P QY+   +L + I    
Sbjct: 247 ELLSQIKIFYESENESSPSIFSIHLKRDGCSF----------PPQYS---ALQRIIKKFK 293

Query: 295 AALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWE 354
             + LDP TAH  LI+S+D   V +     Q +   PKRF V+  VLG   F SG H+WE
Sbjct: 294 VEIILDPETAHPNLIVSEDKKRVRFTK-RKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWE 352

Query: 355 VVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLD 414
           + V +K++W IG+  ++   K        +  + I + D   ++    P T L +  K  
Sbjct: 353 IEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFP-TPLLLEVKAR 411

Query: 415 KVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINT 472
            +G+FLDY+ G + FYN  + S + TF + F G L  YF        G + QPLRI T
Sbjct: 412 AIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYV------GPDSQPLRICT 463


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  169 bits (427), Expect = 7e-42
 Identities = 125/468 (26%), Positives = 209/468 (44%), Gaps = 26/468 (5%)

Query: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWV-------RQEAQGARDCPEC 53
           +A  L++E  CSICL  + DPV   C H FCR CI   W        R++ +G+  CPEC
Sbjct: 6   LARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPEC 65

Query: 54  RRTFAEPALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCF 112
           R    +  L P+  L  + E     P        +    CQ H + +KLFC  D++ +C 
Sbjct: 66  REMSPQRNLLPNRLLTKVAEMAQQHP------GLQKQDLCQEHHEPLKLFCQKDQSPICV 119

Query: 113 FCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQ-LAETKSST 171
            C E   H  H+V   ++A    + +L++ ++ L++ +   T  LQ  + Q LAE +   
Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLRE-QITRTGNLQAREEQSLAEWQGKV 178

Query: 172 KSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQI 231
           K  R  I   FE+++  L E ++ +L+ LE +   T + + + V    +Q   ++     
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 232 LQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIH 291
           L+ER  +            LS +    +    +     P +    P Q  + +   +D+ 
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVV 298

Query: 292 PVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVH 351
           P       D  +A+  L+L +       G+        S  RF      +G  AFSSG H
Sbjct: 299 P-------DATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRH 351

Query: 352 YWEVV--VAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNV 409
           YWEV   +     W +G+  +  SRK  +   P  GF+ + +  G +Y +     T + +
Sbjct: 352 YWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML 411

Query: 410 RDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFRE-KFPGKLCSYFSPG 456
            +    +G+FLD++ G + FY+  D S L+T+ +  FPG L  +F  G
Sbjct: 412 MEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLG 459


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  169 bits (427), Expect = 7e-42
 Identities = 125/468 (26%), Positives = 209/468 (44%), Gaps = 26/468 (5%)

Query: 1   MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWV-------RQEAQGARDCPEC 53
           +A  L++E  CSICL  + DPV   C H FCR CI   W        R++ +G+  CPEC
Sbjct: 6   LARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPEC 65

Query: 54  RRTFAEPALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCF 112
           R    +  L P+  L  + E     P        +    CQ H + +KLFC  D++ +C 
Sbjct: 66  REMSPQRNLLPNRLLTKVAEMAQQHP------GLQKQDLCQEHHEPLKLFCQKDQSPICV 119

Query: 113 FCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQ-LAETKSST 171
            C E   H  H+V   ++A    + +L++ ++ L++ +   T  LQ  + Q LAE +   
Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLRE-QITRTGNLQAREEQSLAEWQGKV 178

Query: 172 KSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQI 231
           K  R  I   FE+++  L E ++ +L+ LE +   T + + + V    +Q   ++     
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 232 LQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIH 291
           L+ER  +            LS +    +    +     P +    P Q  + +   +D+ 
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVV 298

Query: 292 PVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVH 351
           P       D  +A+  L+L +       G+        S  RF      +G  AFSSG H
Sbjct: 299 P-------DATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRH 351

Query: 352 YWEVV--VAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNV 409
           YWEV   +     W +G+  +  SRK  +   P  GF+ + +  G +Y +     T + +
Sbjct: 352 YWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML 411

Query: 410 RDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFRE-KFPGKLCSYFSPG 456
            +    +G+FLD++ G + FY+  D S L+T+ +  FPG L  +F  G
Sbjct: 412 MEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLG 459


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  166 bits (419), Expect = 6e-41
 Identities = 129/468 (27%), Positives = 215/468 (45%), Gaps = 26/468 (5%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWV--RQEAQGARDCPECRRTFAEPA 61
           SL DE+ C IC    ++PV++ C H FCR C+T +      + + +  CP C+  F   +
Sbjct: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68

Query: 62  LAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALH 120
             P+ +LAN+VE      L + L        CQ H +K+  FC  D   LC  C E   H
Sbjct: 69  FRPNWQLANVVENIERLQLVSTLGLGEED-VCQEHGEKIYFFCEDDEMQLCVVCREAGEH 127

Query: 121 EQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQL---LKRQLAETKSSTKSLRTT 177
             H +  ++DA    + ++   L+ L+  ERE  + +Q     + Q+  T+ STK  R  
Sbjct: 128 ATHTMRFLEDAAAPYREQIHKCLKCLR-KEREEIQEIQSRENKRMQVLLTQVSTK--RQQ 184

Query: 178 IGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQ-------KVQRYSQQLRKVQEGAQ 230
           +   F  L + L E+Q  +L +LE+     L   ++       ++ R+S  + +++E  +
Sbjct: 185 VISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNE 244

Query: 231 ILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTI---WKSLF 287
                L    R T +        +      E      DFP      PLQ  +    + L 
Sbjct: 245 RPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQAL--PLQREMKMFLEKLC 302

Query: 288 QDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFS 347
            ++   PA ++LDP T+H +L+LS+D     + +   Q   D+P+RFD    VL     +
Sbjct: 303 FELDYEPAHISLDPQTSHPKLLLSEDHQRAQF-SYKWQNSPDNPQRFDRATCVLAHTGIT 361

Query: 348 SGVHYWEVVV--AEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWT 405
            G H W V +  A      +G+  E   RKG ++++P  G + + +  G   +  + P T
Sbjct: 362 GGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFP-T 420

Query: 406 RLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYF 453
           RL ++++  +V V LDY+ G + F NA     +YTF   F  K+  +F
Sbjct: 421 RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  160 bits (406), Expect = 2e-39
 Identities = 79/175 (45%), Positives = 111/175 (63%), Gaps = 2/175 (1%)

Query: 296 ALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEV 355
           A+TLDP TAH +LILS+D   V  G+   QP+ D+P+RFD  VS+LGSE F++G HYWEV
Sbjct: 239 AVTLDPDTAHPKLILSEDQRCVRLGDRR-QPVPDNPQRFDFVVSILGSEYFTTGCHYWEV 297

Query: 356 VVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDK 415
            V +KT+W++G+  E+ SRKG +   P+ G + +    GN+Y A T P T   +++    
Sbjct: 298 YVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRC 357

Query: 416 VGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           VG+FLDY+ G++ FYN  + S ++TF   F G L  +F P   H  GKN  PL I
Sbjct: 358 VGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEP-CLHDGGKNTAPLVI 411


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  160 bits (406), Expect = 2e-39
 Identities = 79/175 (45%), Positives = 111/175 (63%), Gaps = 2/175 (1%)

Query: 296 ALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEV 355
           A+TLDP TAH +LILS+D   V  G+   QP+ D+P+RFD  VS+LGSE F++G HYWEV
Sbjct: 239 AVTLDPDTAHPKLILSEDQRCVRLGDRR-QPVPDNPQRFDFVVSILGSEYFTTGCHYWEV 297

Query: 356 VVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDK 415
            V +KT+W++G+  E+ SRKG +   P+ G + +    GN+Y A T P T   +++    
Sbjct: 298 YVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRC 357

Query: 416 VGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470
           VG+FLDY+ G++ FYN  + S ++TF   F G L  +F P   H  GKN  PL I
Sbjct: 358 VGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEP-CLHDGGKNTAPLVI 411


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  152 bits (383), Expect = 8e-37
 Identities = 126/466 (27%), Positives = 214/466 (45%), Gaps = 50/466 (10%)

Query: 11  CSICLSIYQDPVSLGCEHYFCRRCIT--EHWVRQEAQGARDCPECRRTF-AEPALAPSLK 67
           C++C    +D V++ C H FCR C+        Q +     CP C+    AE  +AP + 
Sbjct: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAP-VP 74

Query: 68  LANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQHQVT 126
           L  + E Y                 C+ H +K+  FC  D   LC FC E   H+ H V 
Sbjct: 75  LGPLGETY-----------------CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVG 117

Query: 127 GIDDAFDELQRELKDQLQAL-------QDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179
            +D+A    +  L+ +L+AL       +D + +  + LQ+L  Q+   K   ++    + 
Sbjct: 118 FLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQ 177

Query: 180 EAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQE-----GAQILQE 234
           +  E+   LL  R + + +++  +    +T + ++V R   Q+++++E      +++LQ+
Sbjct: 178 QELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQD 237

Query: 235 ---RLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIW-KSLFQDI 290
                +  +  TF++  A +S  L  KI        DF     T P    ++ ++L   +
Sbjct: 238 VRVNQSRCEMKTFVSPEA-ISPDLVKKI-------RDFHRKILTLPEMMRMFSENLAHHL 289

Query: 291 HPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGV 350
                 +TLDP TA + L+LS+D   V Y     + L DSP RFD   +VLG   FSSG 
Sbjct: 290 EIDSGVITLDPQTASRSLVLSEDRKSVRY-TRQKKSLPDSPLRFDGLPAVLGFPGFSSGR 348

Query: 351 HYWEV--VVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLN 408
           H W+V   + +     +G+A E   RKG + +    G + +++    Q  A T P T L 
Sbjct: 349 HRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVII-SHQQCWASTSPGTDLP 407

Query: 409 VRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFS 454
           + +    V V LDY+ G +  +NA     ++TF   F GK+  +F+
Sbjct: 408 LSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFA 453


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  149 bits (377), Expect = 4e-36
 Identities = 113/403 (28%), Positives = 190/403 (47%), Gaps = 30/403 (7%)

Query: 93  CQAHDKVK--LFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSE 150
           C+ H K    LFC      +C  C     H+ H+V  I++   E +++++ QL+ L+   
Sbjct: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434

Query: 151 REHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTD 210
           +   E     + +       T++L+  +    E+++  L +++   +  LE D  + +  
Sbjct: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLE-DVGQMVGQ 493

Query: 211 IEQKVQ-RYSQQL------------RKVQEGAQILQE-----RLAET----DRHTFLAGV 248
           I +    R SQ +            ++ Q   ++LQ+       A+T    ++ T    +
Sbjct: 494 IRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEI 553

Query: 249 ASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRL 308
               + L  K      + + F  +  +    + + + +    H V   + LD  TA+  L
Sbjct: 554 KQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVN--VILDAETAYPNL 611

Query: 309 ILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLA 368
           I SDD   V  GN   + L D P+RFD  + VLGS +F SG  YWEV V +KT W++G  
Sbjct: 612 IFSDDLKSVRLGNKWER-LPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGAC 670

Query: 369 HEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLI 428
             + SRKG++ + P  G++ ++M   N+Y A + P TRL +++   +VG+F+DY  G + 
Sbjct: 671 KTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSIS 730

Query: 429 FYNADDMSWLYTFRE-KFPGKLCSYFSPGQSHANGKNVQPLRI 470
           FYN    S +YTF    F G L   FSPG +   GKN  PL I
Sbjct: 731 FYNVTARSHIYTFASCSFSGPLQPIFSPG-TRDGGKNTAPLTI 772


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  147 bits (370), Expect = 3e-35
 Identities = 114/443 (25%), Positives = 194/443 (43%), Gaps = 26/443 (5%)

Query: 26  CEHYFCRRCITEHWV-------RQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSSF 78
           C H FCR CI   W        R++ +G+  CPECR    +  L P+  L  + E     
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63

Query: 79  PLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQR 137
           P        +    CQ H + +KLFC  D++ +C  C E   H  H+V   ++A    + 
Sbjct: 64  P------GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKL 117

Query: 138 ELKDQLQALQDSEREHTEALQLLKRQ-LAETKSSTKSLRTTIGEAFERLHRLLRERQKAM 196
           +L++ ++ L++ +   T  LQ  + Q LAE +   K  R  I   FE+++  L E ++ +
Sbjct: 118 KLEEDMEYLRE-QITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRL 176

Query: 197 LEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLK 256
           L+ LE +   T + + + V    +Q   ++     L+ER  +            LS +  
Sbjct: 177 LQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNN 236

Query: 257 GKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTI 316
             +    +     P +    P Q  + +   +D+ P       D  +A+  L+L +    
Sbjct: 237 VSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVP-------DATSAYPYLLLYESRQR 289

Query: 317 VAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVV--VAEKTQWVIGLAHEAASR 374
              G+        S  RF      +G  AFSSG HYWEV   +     W +G+  +  SR
Sbjct: 290 RYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSR 349

Query: 375 KGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADD 434
           K  +   P  GF+ + +  G +Y +     T + + +    +G+FLD++ G + FY+  D
Sbjct: 350 KDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD 409

Query: 435 MSWLYTFRE-KFPGKLCSYFSPG 456
            S L+T+ +  FPG L  +F  G
Sbjct: 410 GSHLHTYSQATFPGPLQPFFCLG 432


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  146 bits (368), Expect = 5e-35
 Identities = 128/485 (26%), Positives = 218/485 (44%), Gaps = 51/485 (10%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQ----GARDCPECRRTFAE 59
           ++++E+ C ICL +  +P+SL C H  CR CIT     +EA     G   CP C  +++ 
Sbjct: 8   NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVS--NKEAVTSMGGKSSCPVCGISYSF 65

Query: 60  PALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPA 118
             L  +  LANIVER     L      +R    C  H +K+ LFC  DR ++C+ C+   
Sbjct: 66  EHLQANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQ 123

Query: 119 LHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTI 178
            H  H     ++ F E Q +L+  L+ L+  E E  +    ++ +    K   ++ R  I
Sbjct: 124 EHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRI 183

Query: 179 GEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAE 238
              F++L  +L   ++  L+ LE +  +TL    +      QQ + V+E    ++ R   
Sbjct: 184 QTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQW 243

Query: 239 TDRHTF--LAGVASLSE--RLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVP 294
           +       ++G+   SE  RLK    +  +  +   T  +   L   +   +F+++  V 
Sbjct: 244 STMELLQDMSGIMKWSEIWRLK----KPKMVSKKLKTVFHAPDLSRML--QMFRELTAVR 297

Query: 295 ---AALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVH 351
                +TL+    +  L+LS+D   V    + P    +          VLGS+ FSSG H
Sbjct: 298 CYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN--------YGVLGSQYFSSGKH 349

Query: 352 YWEVVVAEKTQWVIGLAHEAASRKGSIQI-------------QPSRGFYCIVMHDGNQYS 398
           YWEV V++KT W++G+     SR     +             +P  G++ I + +  +Y 
Sbjct: 350 YWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 409

Query: 399 ACTEPWT------RLNVRDKLDKVGVFLDYDQGLLIFYNADDM-SWLYTFRE-KFPGKLC 450
              E  +       L++     +VGVFLDY+ G++ F+N     S +Y F +  F   + 
Sbjct: 410 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 469

Query: 451 SYFSP 455
            YF+P
Sbjct: 470 PYFNP 474


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  146 bits (368), Expect = 5e-35
 Identities = 128/485 (26%), Positives = 218/485 (44%), Gaps = 51/485 (10%)

Query: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQ----GARDCPECRRTFAE 59
           ++++E+ C ICL +  +P+SL C H  CR CIT     +EA     G   CP C  +++ 
Sbjct: 8   NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVS--NKEAVTSMGGKSSCPVCGISYSF 65

Query: 60  PALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPA 118
             L  +  LANIVER     L      +R    C  H +K+ LFC  DR ++C+ C+   
Sbjct: 66  EHLQANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQ 123

Query: 119 LHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTI 178
            H  H     ++ F E Q +L+  L+ L+  E E  +    ++ +    K   ++ R  I
Sbjct: 124 EHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRI 183

Query: 179 GEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAE 238
              F++L  +L   ++  L+ LE +  +TL    +      QQ + V+E    ++ R   
Sbjct: 184 QTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQW 243

Query: 239 TDRHTF--LAGVASLSE--RLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVP 294
           +       ++G+   SE  RLK    +  +  +   T  +   L   +   +F+++  V 
Sbjct: 244 STMELLQDMSGIMKWSEIWRLK----KPKMVSKKLKTVFHAPDLSRML--QMFRELTAVR 297

Query: 295 ---AALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVH 351
                +TL+    +  L+LS+D   V    + P    +          VLGS+ FSSG H
Sbjct: 298 CYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN--------YGVLGSQYFSSGKH 349

Query: 352 YWEVVVAEKTQWVIGLAHEAASRKGSIQI-------------QPSRGFYCIVMHDGNQYS 398
           YWEV V++KT W++G+     SR     +             +P  G++ I + +  +Y 
Sbjct: 350 YWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 409

Query: 399 ACTEPWT------RLNVRDKLDKVGVFLDYDQGLLIFYNADDM-SWLYTFRE-KFPGKLC 450
              E  +       L++     +VGVFLDY+ G++ F+N     S +Y F +  F   + 
Sbjct: 410 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 469

Query: 451 SYFSP 455
            YF+P
Sbjct: 470 PYFNP 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,623,138
Number of Sequences: 37866
Number of extensions: 850334
Number of successful extensions: 5916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 561
Number of HSP's that attempted gapping in prelim test: 3952
Number of HSP's gapped (non-prelim): 2006
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.