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Search of human proteins with 215599015
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215599015 dyskerin isoform 2 [Homo sapiens]
(509 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215599015 dyskerin isoform 2 [Homo sapiens] 1008 0.0
gi|4503337 dyskerin isoform 1 [Homo sapiens] 1001 0.0
gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo sa... 67 4e-11
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 45 2e-04
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 44 3e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 44 5e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 44 5e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 44 5e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 44 5e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 44 5e-04
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 43 8e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 42 0.001
gi|4557509 cylicin 2 [Homo sapiens] 42 0.001
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 42 0.002
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 41 0.002
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 41 0.002
gi|5803092 methionyl aminopeptidase 2 [Homo sapiens] 40 0.005
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 39 0.009
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 39 0.009
gi|28274705 family with sequence similarity 9, member A [Homo sa... 39 0.009
gi|168229156 NFKB activating protein [Homo sapiens] 39 0.011
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 39 0.011
gi|9257180 adducin 2 isoform c [Homo sapiens] 39 0.011
gi|9257192 adducin 2 isoform a [Homo sapiens] 39 0.011
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ... 39 0.011
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ... 39 0.011
gi|125656165 THO complex 2 [Homo sapiens] 39 0.015
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 38 0.019
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 38 0.019
gi|169169855 PREDICTED: similar to hCG34808 [Homo sapiens] 38 0.025
>gi|215599015 dyskerin isoform 2 [Homo sapiens]
Length = 509
Score = 1008 bits (2607), Expect = 0.0
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD
Sbjct: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
Query: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH
Sbjct: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
Query: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL
Sbjct: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
Query: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG
Sbjct: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
Query: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV
Sbjct: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
Query: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH
Sbjct: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKK 420
GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKK
Sbjct: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKK 420
Query: 421 EVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLES 480
EVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLES
Sbjct: 421 EVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLES 480
Query: 481 GAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
GAEPGDGDSDTTKKKKKKKKAKEVELVSE
Sbjct: 481 GAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
>gi|4503337 dyskerin isoform 1 [Homo sapiens]
Length = 514
Score = 1001 bits (2587), Expect = 0.0
Identities = 508/514 (98%), Positives = 509/514 (99%), Gaps = 5/514 (0%)
Query: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD
Sbjct: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
Query: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH
Sbjct: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
Query: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL
Sbjct: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
Query: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG
Sbjct: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
Query: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV
Sbjct: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
Query: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH
Sbjct: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQD----- 415
GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ+
Sbjct: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS 420
Query: 416 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 475
ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK
Sbjct: 421 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 480
Query: 476 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE
Sbjct: 481 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
>gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo
sapiens]
Length = 349
Score = 67.0 bits (162), Expect = 4e-11
Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 54/258 (20%)
Query: 89 TGFINLDKPSNPSSHEVV----------------AWIRRILRVEKTGHSGTLDPKVTGCL 132
+G + KP P+S E++ W +R + K GH GTLD G L
Sbjct: 69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128
Query: 133 IVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRA-----------------LET 175
+V I T+++ S S K Y I L A + R L+
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188
Query: 176 LTGALFQRPPLIAAVKRQ-LRVRTIYE-SKMIEYDPERRLGIFWVS-------------- 219
TG + Q PPL +A+K+ R+ T+ + +++E P R + ++ +S
Sbjct: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248
Query: 220 CEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDE 279
C G YIR+L +G L + EL R + G + ++H + + +W D+
Sbjct: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALP-----EDKWTIDDIAQS 303
Query: 280 SYLRRVVYPLEKLLTSHK 297
++P E L K
Sbjct: 304 LEHCSSLFPAELALKKSK 321
>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
Length = 529
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/85 (34%), Positives = 42/85 (49%)
Query: 418 AKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAG 477
+KK + +V K ++ + AK AK K + E E +E + K+KKK K K K
Sbjct: 440 SKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEE 499
Query: 478 LESGAEPGDGDSDTTKKKKKKKKAK 502
S EP + + +KKKKKK K
Sbjct: 500 PLSEEEPCTSTAIASPEKKKKKKKK 524
Score = 32.3 bits (72), Expect = 1.0
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
Query: 437 AKTAKRKRESESES-----DETPPAAP------QLIKKEKKKSKKDKKAK--AGLESGAE 483
AKT K + +SE ++ D T P Q+ K+++ KK KKAK +E E
Sbjct: 414 AKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEE 473
Query: 484 PGDGDSDTTKKKKKKKKAKEVELVSE 509
+ + T KKKKK+ K+ + E
Sbjct: 474 EKVAEEEETSVKKKKKRGKKKHIKEE 499
Score = 31.6 bits (70), Expect = 1.8
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 16/93 (17%)
Query: 389 KKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRE--- 445
KK I+Q +DK + T+ K+ + AK +V E + +V E + K+K++
Sbjct: 441 KKRKIEQ--VDKEDEITE------KKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGK 492
Query: 446 -----SESESDETPPAAPQLIKKEKKKSKKDKK 473
E S+E P + + EKKK KK K+
Sbjct: 493 KKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKR 525
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 28/130 (21%)
Query: 404 PTDSTPATWKQDESAK-------KEVVAEVVKAPQVVAEAAKTAKRKRESE--------S 448
PT+ P+ KQ +K K V+++ K +VV E AK A+ + E
Sbjct: 305 PTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAK 364
Query: 449 ESDETPPAAP-----------QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKK--K 495
ES E PP P + +K EK+K KDK K L+ + D KK K
Sbjct: 365 ESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIK 424
Query: 496 KKKKKAKEVE 505
K++K+ K+ E
Sbjct: 425 KERKELKKDE 434
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQ 431
E P K K K+ + +K GK + + + AK E E+ K
Sbjct: 1298 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS-------QGAKDEPEEELQKGMG 1350
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V ++ + ++ + +SD+ KK+K+K +K KKAK A D +S +
Sbjct: 1351 TVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKAKK-----ASTKDSESPS 1397
Query: 492 TKKKKKKKKAKE 503
KKKKKKKK E
Sbjct: 1398 QKKKKKKKKTAE 1409
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQ 431
E P K K K+ + +K GK + + + AK E E+ K
Sbjct: 1337 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS-------QGAKDEPEEELQKGMG 1389
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V ++ + ++ + +SD+ KK+K+K +K KKAK A D +S +
Sbjct: 1390 TVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKAKK-----ASTKDSESPS 1436
Query: 492 TKKKKKKKKAKE 503
KKKKKKKK E
Sbjct: 1437 QKKKKKKKKTAE 1448
Score = 31.6 bits (70), Expect = 1.8
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 2/123 (1%)
Query: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRE 445
A+ K M+ G D + T S+ + D K V VKA V + + K
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSD--ETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
Query: 446 SESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
D TP + K+ K ++++++ E + + T + K +K +V
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
Query: 506 LVS 508
S
Sbjct: 302 AAS 304
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQ 431
E P K K K+ + +K GK + + + AK E E+ K
Sbjct: 1374 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS-------QGAKDEPEEELQKGMG 1426
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V ++ + ++ + +SD+ KK+K+K +K KKAK A D +S +
Sbjct: 1427 TVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKAKK-----ASTKDSESPS 1473
Query: 492 TKKKKKKKKAKE 503
KKKKKKKK E
Sbjct: 1474 QKKKKKKKKTAE 1485
Score = 31.6 bits (70), Expect = 1.8
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 2/123 (1%)
Query: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRE 445
A+ K M+ G D + T S+ + D K V VKA V + + K
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSD--ETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
Query: 446 SESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
D TP + K+ K ++++++ E + + T + K +K +V
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
Query: 506 LVS 508
S
Sbjct: 302 AAS 304
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQ 431
E P K K K+ + +K GK + + + AK E E+ K
Sbjct: 1297 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS-------QGAKDEPEEELQKGMG 1349
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V ++ + ++ + +SD+ KK+K+K +K KKAK A D +S +
Sbjct: 1350 TVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKAKK-----ASTKDSESPS 1396
Query: 492 TKKKKKKKKAKE 503
KKKKKKKK E
Sbjct: 1397 QKKKKKKKKTAE 1408
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQ 431
E P K K K+ + +K GK + + + AK E E+ K
Sbjct: 1336 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS-------QGAKDEPEEELQKGMG 1388
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V ++ + ++ + +SD+ KK+K+K +K KKAK A D +S +
Sbjct: 1389 TVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKAKK-----ASTKDSESPS 1435
Query: 492 TKKKKKKKKAKE 503
KKKKKKKK E
Sbjct: 1436 QKKKKKKKKTAE 1447
Score = 31.6 bits (70), Expect = 1.8
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 2/123 (1%)
Query: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRE 445
A+ K M+ G D + T S+ + D K V VKA V + + K
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSD--ETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
Query: 446 SESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
D TP + K+ K ++++++ E + + T + K +K +V
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
Query: 506 LVS 508
S
Sbjct: 302 AAS 304
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 42.7 bits (99), Expect = 8e-04
Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Query: 371 MERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAP 430
+E D P+ L +A ++++GL +K G T A K+ +K V + K P
Sbjct: 1299 VETDKKPQGKQLQTRADYLLKLLRKGL-EKKGAVTGGEEAKLKK----RKPRVKKENKVP 1353
Query: 431 QVVAEAAKTAKRKRESESESDETPPAAPQLIK---KEKKKSKKDKKAKAGLESGAEPGDG 487
++ E R S++ S+E L K K+K+K K++K+ K S + +G
Sbjct: 1354 RLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEG 1413
Query: 488 DSDTTKKKKKKKKAK 502
D + K K KK+K K
Sbjct: 1414 DKERKKSKDKKEKPK 1428
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 435 EAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLES-GAEPGDGDSDTTK 493
+ K AK+ ++ESE + + +KK KK K K K ES AE GD +
Sbjct: 287 DTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 346
Query: 494 KKKKKKKAKE 503
KK KKK K+
Sbjct: 347 TKKDKKKLKK 356
Score = 35.0 bits (79), Expect = 0.16
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 413 KQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 472
K+D K+ V + K V + T +S+ E +T +L K +KKK K
Sbjct: 307 KKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKY 366
Query: 473 KAKAGLESG-AEPGDGDSDTTKKKK----KKKKAKEV 504
ESG A+ DS KK KKK AK++
Sbjct: 367 PESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Score = 31.2 bits (69), Expect = 2.3
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 13/120 (10%)
Query: 399 DKHGKPTDSTPATWKQDES--AKKEVVAEVVKAPQVVAEAAKTAKR---KRESESESDET 453
DK TD+ + +ES A E + K + + K +K+ K++++ ++ T
Sbjct: 425 DKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAEST 484
Query: 454 PPAAPQLIKK------EKKKSKKD--KKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
+ +KK EKK SKKD K A+ ES D S T K K K + E
Sbjct: 485 EMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544
Score = 30.8 bits (68), Expect = 3.0
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query: 398 LDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAA 457
L K K D K S E E ++ + + K +K + ++DE A
Sbjct: 387 LKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDA 446
Query: 458 PQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
K + KK KKD+K G + D KKK KK A+ E+ S+
Sbjct: 447 DSEPKGDSKKGKKDEK------KGKKDSKKDD---KKKDAKKNAESTEMESD 489
Score = 30.8 bits (68), Expect = 3.0
Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 7/115 (6%)
Query: 399 DKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAP 458
DK T +T + E KE + K + K + + E +++D P
Sbjct: 395 DKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDS 454
Query: 459 QLIKKEKKK-------SKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVEL 506
+ KK++KK K K AK ES D + KK K+KK + ++
Sbjct: 455 KKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDI 509
Score = 29.6 bits (65), Expect = 6.8
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 23/119 (19%)
Query: 385 KASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKR 444
K KK K+ +K G P K+D K A ++ Q+V E K
Sbjct: 107 KTHLKKAEYKKSKDEKGGTPL-------KKDSKKKGGSYATNPESKQIVEE-------KT 152
Query: 445 ESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 503
+ ++E+D+TP K ++++ KK+K+ E+ P +S T K +K K+
Sbjct: 153 KRQNEADKTP-------LKSSHENEQSKKSKSSSET--NPESQNSKTVSKNCSQKDKKD 202
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 5/94 (5%)
Query: 413 KQDESAKKEVVA---EVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSK 469
K+D K++ E + A + + K A++ ++S +ES++ A + KK+KK S
Sbjct: 138 KKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSN 197
Query: 470 KDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 503
K K + ES E G + D+ K KK KK K+
Sbjct: 198 KGK--DSATESEGEKGGTEKDSKKGKKDSKKGKD 229
Score = 37.0 bits (84), Expect = 0.043
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 11/113 (9%)
Query: 403 KPTDSTPATWKQDESAKK----EVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAP 458
KPT + K E KK + + + + K +K+ ++ E +E A
Sbjct: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDA-- 157
Query: 459 QLIKKEKKKSKKD--KKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
KK+ KK KKD K + ES E G D K KK K K+ SE
Sbjct: 158 ---KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESE 207
Score = 35.4 bits (80), Expect = 0.12
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 394 KQGLLD-KHGKPT----DSTPATWKQDESAKKEVVA--EVVKAPQVVAEAAKTAK-RKRE 445
K+G D K GK + + A K+DE KK+ E A + E K K +K+
Sbjct: 218 KKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKP 277
Query: 446 SESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKK--KKKAKE 503
S ++SD + + K+ KK + KD K A ++ E D D K KK KK AK+
Sbjct: 278 SSTDSD----SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKK 333
Score = 33.1 bits (74), Expect = 0.61
Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 383 GPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVK--APQVVAEAAKTA 440
G K S+K I++G +K DS ++ +E K A + + K +
Sbjct: 137 GKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS 196
Query: 441 KRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLES----GAEPGDGDSDTTK--- 493
+ ++S +ES+ + KK KK SKK K + L++ + DG D K
Sbjct: 197 NKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDE 256
Query: 494 KKKKKKKAKEVE 505
K KK AKE++
Sbjct: 257 SKDAKKDAKEIK 268
Score = 33.1 bits (74), Expect = 0.61
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 393 IKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDE 452
IK+G DK K ST + K D KKE + K + VA K K ++S+ D
Sbjct: 267 IKKGKKDK--KKPSSTDSDSKDD--VKKESKKDATKDAKKVA---KKDTEKESADSKKDA 319
Query: 453 TPPAAPQLIKKEKKKSKKDKKAKA 476
A K KK +KKD+K A
Sbjct: 320 KKNAKKDAKKDAKKNAKKDEKKDA 343
Score = 30.0 bits (66), Expect = 5.2
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 4/110 (3%)
Query: 399 DKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAP 458
D + D K ++ KK+ A + E T K ++ + +S + +A
Sbjct: 173 DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAI 232
Query: 459 QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTT---KKKKKKKKAKEVE 505
+L + K KKD+ K G E D D K KK KKK +
Sbjct: 233 EL-QAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTD 281
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 403 KPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIK 462
K D TP K++E KKE V + VK E K K++ + E + + P + +K
Sbjct: 662 KKEDKTPI--KKEEKPKKEEVKKEVKK-----EIKKEEKKEPKKEVKKETPPKEVKKEVK 714
Query: 463 KEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKA 501
KE+KK K ++ + E P D +T + KK A
Sbjct: 715 KEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPA 753
Score = 37.7 bits (86), Expect = 0.025
Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 367 KRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEV 426
K +M + P K P ++K++ K+ + + K + +K V E
Sbjct: 583 KEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKET 642
Query: 427 VKAPQVVAEAAKTAKRKRESESESDETP------PAAPQLIKKEKKKSKKDKKAKAGLES 480
P+ E + K K+E + D+TP P ++ K+ KK+ KK++K + E
Sbjct: 643 KVKPEDKKEEKE--KPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEV 700
Query: 481 GAEPGDGDSDTTKKKKKKKKAKEVE 505
E + KK++KK+ K+ E
Sbjct: 701 KKETPPKEVKKEVKKEEKKEVKKEE 725
Score = 37.4 bits (85), Expect = 0.033
Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 25/132 (18%)
Query: 387 SQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKE---VVAEVVK--APQVVAEAAKTAK 441
S++K+M+K+ DK K T++ P+ +++ +K+E V AEV + A V +AAK
Sbjct: 582 SKEKVMVKK---DKPIK-TETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKT 637
Query: 442 RKRES----ESESDETPPAAPQLIKKEK----KKSKKDKKAKAGLESGAEPGDGDSDTTK 493
K+E+ E + +E ++ KKE KK +K KK + E E K
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKE--------IK 689
Query: 494 KKKKKKKAKEVE 505
K++KK+ KEV+
Sbjct: 690 KEEKKEPKKEVK 701
Score = 33.5 bits (75), Expect = 0.47
Identities = 37/150 (24%), Positives = 60/150 (40%), Gaps = 19/150 (12%)
Query: 367 KRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPT------DSTPATWKQD--ESA 418
K V + D P K PK + K +K+ + + K ++ P K++ +
Sbjct: 658 KEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEE 717
Query: 419 KKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGL 478
KKEV E + + + + K AK+ SE+ + P++ KKE+ K A
Sbjct: 718 KKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPK 777
Query: 479 ESGAEPGDGDSDTTKKKKKKKKAKEVELVS 508
E G K K KK+ K E V+
Sbjct: 778 EKG-----------KIKVIKKEGKAAEAVA 796
Score = 29.3 bits (64), Expect = 8.9
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Query: 425 EVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEP 484
EV K P AE+ E E E ++TP + K+ +K + AG E +E
Sbjct: 883 EVTKGP---AESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSET 939
Query: 485 GDGDSDTTKKKKKKKKAKEVE 505
GD ++K + ++A+E E
Sbjct: 940 GD-----YEEKAETEEAEEPE 955
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 402 GKPTDSTPATW-----KQDESAKKEVVAEVVKAPQVVAEAAKT----AKRKRES----ES 448
GKP + T K+ S+ A+ K P+++++ + + K K ES +
Sbjct: 156 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
Query: 449 ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
ES+E PP + K+EK K K K+K ++S A DS TTKK + K KE E
Sbjct: 216 ESEEEPPK--KTAKREKPKQKATSKSKKSVKS-ANVKKADSSTTKKNQNSSK-KESE 268
Score = 30.0 bits (66), Expect = 5.2
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 414 QDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQL-IKKEKKKSKKDK 472
+DE KE ++ KTAKR++ + + ++ + +KK + K
Sbjct: 200 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKN 259
Query: 473 KAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
+ + ES +E D KK KK +E++
Sbjct: 260 QNSSKKESESEDSSDDEPLIKKLKKPPTDEELK 292
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 402 GKPTDSTPATW-----KQDESAKKEVVAEVVKAPQVVAEAAKT----AKRKRES----ES 448
GKP + T K+ S+ A+ K P+++++ + + K K ES +
Sbjct: 190 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 249
Query: 449 ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
ES+E PP + K+EK K K K+K ++S A DS TTKK + K KE E
Sbjct: 250 ESEEEPPK--KTAKREKPKQKATSKSKKSVKS-ANVKKADSSTTKKNQNSSK-KESE 302
Score = 30.0 bits (66), Expect = 5.2
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 414 QDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQL-IKKEKKKSKKDK 472
+DE KE ++ KTAKR++ + + ++ + +KK + K
Sbjct: 234 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKN 293
Query: 473 KAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
+ + ES +E D KK KK +E++
Sbjct: 294 QNSSKKESESEDSSDDEPLIKKLKKPPTDEELK 326
>gi|5803092 methionyl aminopeptidase 2 [Homo sapiens]
Length = 478
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 429 APQVVAEAAKTAKRKRES--------ESESDETPPAAPQLIKKEKKKSK-KDKKAKAGLE 479
A EAAK +RK++ E E D+ A+ + ++ ++S +DK+ E
Sbjct: 27 AASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDE 86
Query: 480 SGAEPGDGDSDTTKKKKKKKKAKEVE 505
G GDG + KKKKKKK+ +V+
Sbjct: 87 DGDGDGDGATGKKKKKKKKKRGPKVQ 112
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 39.3 bits (90), Expect = 0.009
Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 10/108 (9%)
Query: 400 KHGKPTDSTPATWKQDESA--KKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAA 457
K + T+ T T +++E +KE E K + + +T KRK + E E
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK---- 63
Query: 458 PQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
+K KKK +++++ + E E + + + +++KKKKK + E
Sbjct: 64 ----RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Score = 38.5 bits (88), Expect = 0.015
Identities = 24/106 (22%), Positives = 50/106 (47%)
Query: 400 KHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQ 459
K K T+ T T + +E +KE + + + + K ++ E E +E +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 460 LIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
KK+K++ +++++ + E E + KKKKK+++ +E E
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 37.0 bits (84), Expect = 0.043
Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 399 DKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAP 458
+K GK + K+ E KK E K + + K ++K++ E E +E
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 459 QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 503
+ ++E+K+ + +K K E + KKKK+++K K+
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEE------EEEKKKKRRRKTKK 122
Score = 36.2 bits (82), Expect = 0.073
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 438 KTAKRKRESESESDETPPAAPQLIKKEKKKSKK-----DKKAKAGLESGAEPGDGDSDTT 492
K K+K++ E++ET + K+ K+K K+ +K+ K + + + + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 493 KKKKKKKKAKEVE 505
K+K+K+KK KE E
Sbjct: 61 KRKRKRKKKKEEE 73
Score = 35.0 bits (79), Expect = 0.16
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 438 KTAKRKRESES-----ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTT 492
K K+K+E+E E++E + +K K+K K+ +K K E+ + +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 493 KKKKKKKKAKEVELVSE 509
+K+K+KKK +E E E
Sbjct: 62 RKRKRKKKKEEEEREEE 78
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 39.3 bits (90), Expect = 0.009
Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 371 MERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKP-TDSTPATWKQDESA--KKEVVAEVV 427
+E DT +K K +++K +K KP +D T +++E+ K + V +
Sbjct: 11 LESDTAMKKGETLRKQTEEK--------EKKEKPKSDKTEEIAEEEETVFPKAKQVKKKA 62
Query: 428 KAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAG-LESGAEPGD 486
+ +V + K+ K K++ E ++ P L KK++ KK +K + EP +
Sbjct: 63 EPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSE 122
Query: 487 GDSDTTKKKKKKKK 500
+ D K KK KK+
Sbjct: 123 EEIDAPKPKKMKKE 136
Score = 31.2 bits (69), Expect = 2.3
Identities = 26/127 (20%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 384 PKASQKKLMIKQGLLDKHG---KPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTA 440
PKA Q K + +D + K + D S K + + + + + ++KT
Sbjct: 53 PKAKQVKKKAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTK 112
Query: 441 KRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESG---AEPGDGDSDTTKKKKK 497
K + E +E P+ +KKEK+ + + ++ L++G EP S+ ++
Sbjct: 113 KVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESN 172
Query: 498 KKKAKEV 504
+ +E+
Sbjct: 173 SEIEQEI 179
Score = 30.8 bits (68), Expect = 3.0
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 11/78 (14%)
Query: 438 KTAKRKRESESESDETP-PAAPQLIKKEK-----KKSKKDKKAKAGLESGAEPGDGD-SD 490
K K E +E +ET P A Q+ KK + S K KKAK EP D S
Sbjct: 35 KPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAK----KKEEPSQNDISP 90
Query: 491 TTKKKKKKKKAKEVELVS 508
TK +KKK+ E ++VS
Sbjct: 91 KTKSLRKKKEPIEKKVVS 108
Score = 30.0 bits (66), Expect = 5.2
Identities = 20/68 (29%), Positives = 32/68 (47%)
Query: 441 KRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKK 500
K + ++ ESD L K+ ++K KK+K E AE + K+ KKK +
Sbjct: 4 KLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAE 63
Query: 501 AKEVELVS 508
EV++ S
Sbjct: 64 PSEVDMNS 71
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 39.3 bits (90), Expect = 0.009
Identities = 34/154 (22%), Positives = 75/154 (48%), Gaps = 18/154 (11%)
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATW-----KQD 415
G+ AK + + +++ Y + +A +KK + +Q +H + + + K D
Sbjct: 130 GLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDD 189
Query: 416 ESAKKEVVA---EVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 472
E+ + E A E A + A AA+ + E E E +E ++EK++ +++
Sbjct: 190 EAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEE---------EEEKEEEEEEG 240
Query: 473 KAKAGLESGAE-PGDGDSDTTKKKKKKKKAKEVE 505
+ + G E G E G G+ + T++++++++ +E E
Sbjct: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEE 274
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 25/126 (19%)
Query: 377 PRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEA 436
P WGL PK + DS T +DE KK + A
Sbjct: 143 PEVWGLSPKNPEP----------------DSDEHTPVEDEEPKKSTTS---------AST 177
Query: 437 AKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKK 496
++ K+K+ S S+ + K++ KK +D + + E+ + D K KK
Sbjct: 178 SEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKK 237
Query: 497 KKKKAK 502
K+KK K
Sbjct: 238 KEKKKK 243
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 38.9 bits (89), Expect = 0.011
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 34/145 (23%)
Query: 359 DHGIVAKIKRVIMERDTYPRKWGLG-PKASQKKLMIKQGLLDKHGKPTDSTPATWKQDES 417
D G+ + VI E+++ W G K + KK K+ + K K T T K
Sbjct: 5 DKGVAMEKVHVITEKES---AWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTK---- 57
Query: 418 AKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAG 477
KK E K ++++E E E ++ +KEK+K KK KK K
Sbjct: 58 TKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEK---------EKEKEKKKKKKKKK-- 106
Query: 478 LESGAEPGDGDSDTTKKKKKKKKAK 502
KKKKKK AK
Sbjct: 107 ---------------KKKKKKLNAK 116
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 413 KQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 472
K+ KK+ + K + + T K K+ + + T + K+++K+ +K+K
Sbjct: 29 KKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEK 88
Query: 473 KAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVEL 506
+ + + + + KKKKKKKK K+ +L
Sbjct: 89 EKEK---------EKEKEKKKKKKKKKKKKKKKL 113
Score = 29.3 bits (64), Expect = 8.9
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 432 VVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDT 491
V+ E KR R+ ++ + K+KKK+ KK + + T
Sbjct: 15 VITEKESAWKRGRKKKTTKKKKKKKTTM---KKKKKTTTKKKTTTKTKKRTTTTKKTTTT 71
Query: 492 TKKKKKKKKAKEVELVSE 509
T K+K+K+K KE E E
Sbjct: 72 TTKEKEKEKEKEKEKEKE 89
>gi|9257180 adducin 2 isoform c [Homo sapiens]
Length = 420
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/114 (23%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 385 KASQKKLMI---KQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAK 441
+ +KKL + K+ ++ G P S PA+ Q + + E + +V + + E K +
Sbjct: 265 EVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTE 324
Query: 442 RKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKK 495
+ + +E + T P + +E++++ ++ +K GL D D DT+K K
Sbjct: 325 TSKAATTEPETTQPEGVVVNGREEEQTAEEILSK-GLSQMTTSADTDVDTSKDK 377
>gi|9257192 adducin 2 isoform a [Homo sapiens]
Length = 726
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/114 (23%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 385 KASQKKLMI---KQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAK 441
+ +KKL + K+ ++ G P S PA+ Q + + E + +V + + E K +
Sbjct: 571 EVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTE 630
Query: 442 RKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKK 495
+ + +E + T P + +E++++ ++ +K GL D D DT+K K
Sbjct: 631 TSKAATTEPETTQPEGVVVNGREEEQTAEEILSK-GLSQMTTSADTDVDTSKDK 683
>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 38.9 bits (89), Expect = 0.011
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 12/120 (10%)
Query: 393 IKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDE 452
+K+ G +ST + + KK E P+V +T KRKR S +++
Sbjct: 251 MKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEV-----RTGKRKRSSSEDAES 305
Query: 453 TPPAAP-------QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
P + +IK+ + SK+++ + E + GD + K K+K K K E
Sbjct: 306 LAPRSKVKKIIQKDIIKEASEASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKE 365
Score = 31.6 bits (70), Expect = 1.8
Identities = 27/135 (20%), Positives = 55/135 (40%), Gaps = 7/135 (5%)
Query: 377 PRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEA 436
PRK G+ PK + K + ++++ K K+D KE +
Sbjct: 194 PRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNT-----SI 248
Query: 437 AKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESG--AEPGDGDSDTTKK 494
+K + + SE E+ Q KK+KK+ + + + + +G D+++
Sbjct: 249 SKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAP 308
Query: 495 KKKKKKAKEVELVSE 509
+ K KK + +++ E
Sbjct: 309 RSKVKKIIQKDIIKE 323
>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
sapiens]
Length = 582
Score = 38.9 bits (89), Expect = 0.011
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 12/120 (10%)
Query: 393 IKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDE 452
+K+ G +ST + + KK E P+V +T KRKR S +++
Sbjct: 251 MKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEV-----RTGKRKRSSSEDAES 305
Query: 453 TPPAAP-------QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 505
P + +IK+ + SK+++ + E + GD + K K+K K K E
Sbjct: 306 LAPRSKVKKIIQKDIIKEASEASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKE 365
Score = 31.6 bits (70), Expect = 1.8
Identities = 27/135 (20%), Positives = 55/135 (40%), Gaps = 7/135 (5%)
Query: 377 PRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEA 436
PRK G+ PK + K + ++++ K K+D KE +
Sbjct: 194 PRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNT-----SI 248
Query: 437 AKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESG--AEPGDGDSDTTKK 494
+K + + SE E+ Q KK+KK+ + + + + +G D+++
Sbjct: 249 SKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAP 308
Query: 495 KKKKKKAKEVELVSE 509
+ K KK + +++ E
Sbjct: 309 RSKVKKIIQKDIIKE 323
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 38.5 bits (88), Expect = 0.015
Identities = 30/124 (24%), Positives = 49/124 (39%)
Query: 375 TYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVA 434
T P LG +K + +K + + TP + K+ E KKE A+ K V
Sbjct: 1288 TTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVP 1347
Query: 435 EAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKK 494
A + ++RE E E A ++ KE K + L+S D ++
Sbjct: 1348 NAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQ 1407
Query: 495 KKKK 498
K++K
Sbjct: 1408 KRRK 1411
Score = 37.0 bits (84), Expect = 0.043
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
Query: 413 KQDESAKKEVVAEVVKAPQVVAEAAKTA-KRKRESESE-SDETPPAAPQLIKKEKKKSKK 470
K+ E KKE +V+ + K K +R ++ E + ET P+ KEK+K KK
Sbjct: 1275 KEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKS-DKEKEKFKK 1333
Query: 471 DKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
++KAK P T +++++K+ ++E ++ E
Sbjct: 1334 EEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKE 1372
Score = 30.4 bits (67), Expect = 4.0
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 438 KTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKK-K 496
K ++++E + ++ T P A L K K+K K+++ K + SD K+K K
Sbjct: 1273 KGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFK 1332
Query: 497 KKKKAKE 503
K++KAK+
Sbjct: 1333 KEEKAKD 1339
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 38.1 bits (87), Expect = 0.019
Identities = 28/146 (19%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 365 KIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVA 424
+I R + T + GP + + ++ D+ K D ++ ++++ V
Sbjct: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 231
Query: 425 EV-VKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAE 483
+ + P+ +T K + E E + K+K K + D++A+AG+++
Sbjct: 232 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA--- 288
Query: 484 PGDGDSDTTKKKKKKKKAKEVELVSE 509
D D D +K +KK +++ +L ++
Sbjct: 289 --DEDEDGDEKDEKKHRSQPKDLAAK 312
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 38.1 bits (87), Expect = 0.019
Identities = 28/146 (19%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 365 KIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVA 424
+I R + T + GP + + ++ D+ K D ++ ++++ V
Sbjct: 156 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 215
Query: 425 EV-VKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAE 483
+ + P+ +T K + E E + K+K K + D++A+AG+++
Sbjct: 216 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA--- 272
Query: 484 PGDGDSDTTKKKKKKKKAKEVELVSE 509
D D D +K +KK +++ +L ++
Sbjct: 273 --DEDEDGDEKDEKKHRSQPKDLAAK 296
>gi|169169855 PREDICTED: similar to hCG34808 [Homo sapiens]
Length = 483
Score = 37.7 bits (86), Expect = 0.025
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 43/161 (26%)
Query: 390 KLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVA----------EAAKT 439
K ++ L K T +T A Q+ AK+ +A + PQV A E +
Sbjct: 140 KQIVTAFLGKNRNKTTMTTHAFTIQERFAKR--MAALKNKPQVAAPGPDISKTQVECKRG 197
Query: 440 AKRKRESESESDET-PPAAPQLIKKEKKKSKKDKKAKA---------------------- 476
KR +E+ ++ E+ PP P+ + ++ K K+DK K+
Sbjct: 198 KKRNKEATGKNGESYPPTQPKAKRPKEGKPKRDKVQKSASKEKRARTDGQCRGLCWEESS 257
Query: 477 -----GLESGAEPGDGDSDTTKKKK---KKKKAKEVELVSE 509
G + +P DG T K KK KKK AK VE+ +
Sbjct: 258 EASAQGAGNCVQPPDGQDFTLKPKKTRGKKKAAKPVEVAMD 298
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,353,318
Number of Sequences: 37866
Number of extensions: 866374
Number of successful extensions: 8025
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 5668
Number of HSP's gapped (non-prelim): 1636
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.