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Search of human proteins with 21361103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
(678 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 1348 0.0
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 1053 0.0
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 1052 0.0
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 214 2e-55
gi|13899342 solute carrier [Homo sapiens] 202 8e-52
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 126 8e-29
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 118 2e-26
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 117 5e-26
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 116 8e-26
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 115 2e-25
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 115 2e-25
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 114 3e-25
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 110 3e-24
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 108 1e-23
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 108 2e-23
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 104 3e-22
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 104 3e-22
gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 102 9e-22
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 102 1e-21
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 102 1e-21
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 101 2e-21
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 101 2e-21
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 101 2e-21
gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 100 3e-21
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 100 3e-21
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 100 4e-21
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 99 2e-20
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 97 6e-20
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 97 6e-20
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 96 1e-19
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 1348 bits (3490), Expect = 0.0
Identities = 678/678 (100%), Positives = 678/678 (100%)
Query: 1 MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLL 60
MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLL
Sbjct: 1 MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLL 60
Query: 61 AGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTII 120
AGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTII
Sbjct: 61 AGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTII 120
Query: 121 HHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGL 180
HHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGL
Sbjct: 121 HHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGL 180
Query: 181 DFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLA 240
DFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLA
Sbjct: 181 DFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLA 240
Query: 241 GTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGAL 300
GTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGAL
Sbjct: 241 GTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGAL 300
Query: 301 PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360
PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS
Sbjct: 301 PYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360
Query: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420
GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR
Sbjct: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420
Query: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL 480
DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL
Sbjct: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL 480
Query: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPAD 540
YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPAD
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPAD 540
Query: 541 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600
VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL
Sbjct: 541 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600
Query: 601 LQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKF 660
LQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKF
Sbjct: 601 LQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKF 660
Query: 661 KSPSVAVVQPKAAVAATQ 678
KSPSVAVVQPKAAVAATQ
Sbjct: 661 KSPSVAVVQPKAAVAATQ 678
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 1053 bits (2723), Expect = 0.0
Identities = 521/666 (78%), Positives = 586/666 (87%), Gaps = 3/666 (0%)
Query: 2 AVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLA 61
A KV TKR DP ELR IFL+YAS E +GE +M+P DFV RYL ++ + NPK V+LL+
Sbjct: 3 AAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLS 62
Query: 62 GVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 121
GV DQTKDGLIS+QEF+AFESVLCAPD++F+VAFQLFDK+G GEVTFE+VK++FGQT IH
Sbjct: 63 GVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIH 122
Query: 122 HHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 181
HIPFNWD EF++LHFG RK+HL Y EFTQFL E+QLEHA+QAF +D +++G ++ +D
Sbjct: 123 QHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAID 182
Query: 182 FSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAG 241
F DIMVTIR H+LTPFVEE LV+AAGG+ SHQVSFSYFN FNSLLNNMEL+RKIYSTLAG
Sbjct: 183 FRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAG 242
Query: 242 TRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALP 301
TRKDVEVTKEEF +A ++GQVTP+E+DIL+QLADLY GR+TLADIERIAPL EG LP
Sbjct: 243 TRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLP 302
Query: 302 YNLAELQRQQSPG-LGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360
+NLAE QRQ++ G RP+ LQ+AESAYRF LGSVAGAVGATAVYPIDLVKTRMQNQR +
Sbjct: 303 FNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRST 362
Query: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420
GS VGELMYKNSFDCFKKVLRYEGFFGLYRGL+PQL+GVAPEKAIKLTVNDFVRDKF +
Sbjct: 363 GSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHK 422
Query: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL 480
DGSVPL AE+LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL+V+RDLG FG+
Sbjct: 423 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGI 482
Query: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPAD 540
YKGAKACFLRDIPFSAIYFP YAH K A+E+G V +LL AGA+AG+PAASLVTPAD
Sbjct: 483 YKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPAD 542
Query: 541 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600
VIKTRLQVAARAGQTTYSGVIDCFRKILREEGP A WKG ARVFRSSPQFGVTL+TYEL
Sbjct: 543 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
Query: 601 LQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKF 660
LQRWFYIDFGG+KP GSEP PKSRI +LP NPDH+GGY+LA ATFAGIENKFGLYLP F
Sbjct: 603 LQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLF 661
Query: 661 KSPSVA 666
K PSV+
Sbjct: 662 K-PSVS 666
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 1052 bits (2721), Expect = 0.0
Identities = 522/667 (78%), Positives = 585/667 (87%), Gaps = 4/667 (0%)
Query: 2 AVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLA 61
A KV TKR DP ELR IFL+YAS E +GE +M+P DFV RYL ++ + NPK V+LL+
Sbjct: 3 AAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLS 62
Query: 62 GVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 121
GV DQTKDGLIS+QEF+AFESVLCAPD++F+VAFQLFDK+G GEVTFE+VK++FGQT IH
Sbjct: 63 GVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIH 122
Query: 122 HHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 181
HIPFNWD EF++LHFG RK+HL Y EFTQFL E+QLEHA+QAF +D +++G ++ +D
Sbjct: 123 QHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAID 182
Query: 182 FSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAG 241
F DIMVTIR H+LTPFVEE LV+AAGG+ SHQVSFSYFN FNSLLNNMEL+RKIYSTLAG
Sbjct: 183 FRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAG 242
Query: 242 TRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALP 301
TRKDVEVTKEEF +A ++GQVTP+E+DIL+QLADLY GR+TLADIERIAPL EG LP
Sbjct: 243 TRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLP 302
Query: 302 YNLAELQRQQ--SPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRG 359
+NLAE QRQQ S RP+ LQ+AESAYRF LGSVAGAVGATAVYPIDLVKTRMQNQR
Sbjct: 303 FNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRS 362
Query: 360 SGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTR 419
+GS VGELMYKNSFDCFKKVLRYEGFFGLYRGL+PQL+GVAPEKAIKLTVNDFVRDKF
Sbjct: 363 TGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH 422
Query: 420 RDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFG 479
+DGSVPL AE+LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL+V+RDLG FG
Sbjct: 423 KDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFG 482
Query: 480 LYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPA 539
+YKGAKACFLRDIPFSAIYFP YAH K A+E+G V +LL AGA+AG+PAASLVTPA
Sbjct: 483 IYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPA 542
Query: 540 DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYE 599
DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGP A WKG ARVFRSSPQFGVTL+TYE
Sbjct: 543 DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602
Query: 600 LLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPK 659
LLQRWFYIDFGG+KP GSEP PKSRI +LP NPDH+GGY+LA ATFAGIENKFGLYLP
Sbjct: 603 LLQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPL 661
Query: 660 FKSPSVA 666
FK PSV+
Sbjct: 662 FK-PSVS 667
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 214 bits (545), Expect = 2e-55
Identities = 132/300 (44%), Positives = 168/300 (56%), Gaps = 38/300 (12%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G +AG +G T V+PIDL KTR+QNQ+ G+ +Y + DC K +R EG+FG+YRG
Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQN-----GQRVYTSMSDCLIKTVRSEGYFGMYRGA 69
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
L V PEKAIKL NDF R + ++ + L E+LAG AG QVI T P+E++KI
Sbjct: 70 AVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKI 129
Query: 453 RLQVAGEIT-------------------------TGPRVSALNVLRDL----GIFGLYKG 483
+LQ AG I PR +A + RDL GI GLYKG
Sbjct: 130 QLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKG 189
Query: 484 AKACFLRDIPFSAIYFPVYAHCKLL--LADENGHVGGLNLLAAGAMAGVPAASLVTPADV 541
A LRD+PFS +YFP++A+ L A E ++ L AG +AG AA V P DV
Sbjct: 190 LGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFL-AGCVAGSAAAVAVNPCDV 248
Query: 542 IKTRLQVAAR-AGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600
+KTRLQ R + TYSG++DC RKILR EGPSAF KG R +P FG+ V Y L
Sbjct: 249 VKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFL 308
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/141 (34%), Positives = 67/141 (47%), Gaps = 17/141 (12%)
Query: 264 TPLEIDILYQ--LADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWL 321
T L D+L +A LY G L D+ P + P A L + LGRP
Sbjct: 171 TQLTRDLLRSRGIAGLYKGLGATLLRDV----PFSVVYFPL-FANLNQ-----LGRPASE 220
Query: 322 QIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQN-QRGSGSVVGELMYKNSFDCFKKVL 380
+ + F G VAG+ A AV P D+VKTR+Q+ QRG V E Y DC +K+L
Sbjct: 221 EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRG----VNEDTYSGILDCARKIL 276
Query: 381 RYEGFFGLYRGLIPQLIGVAP 401
R+EG +G + + +AP
Sbjct: 277 RHEGPSAFLKGAYCRALVIAP 297
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 28/197 (14%)
Query: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRL---QVAGEITTGPRVSALNVLRDLGI 477
D + LPA+++ GG AG V P+++ K RL Q + T + +R G
Sbjct: 3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGY 62
Query: 478 FGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVT 537
FG+Y+GA P AI + L+ + + L + AG AG + T
Sbjct: 63 FGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTT 122
Query: 538 PADVIKTRLQVAAR----------AGQTTYSG---------------VIDCFRKILREEG 572
P +++K +LQ A R GQ + G R +LR G
Sbjct: 123 PMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRG 182
Query: 573 PSAFWKGTAARVFRSSP 589
+ +KG A + R P
Sbjct: 183 IAGLYKGLGATLLRDVP 199
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTA 581
L G +AG+ + V P D+ KTRLQ + GQ Y+ + DC K +R EG ++G A
Sbjct: 12 LINGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAA 70
Query: 582 ARVFRSSPQFGVTLVTYELLQ 602
+ +P+ + L + +
Sbjct: 71 VNLTLVTPEKAIKLAANDFFR 91
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 202 bits (514), Expect = 8e-52
Identities = 127/294 (43%), Positives = 157/294 (53%), Gaps = 34/294 (11%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G VAG VG T V+PIDL KTR+QNQ G MYK DC K R EGFFG+YRG
Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKA------MYKGMIDCLMKTARAEGFFGMYRGA 68
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
L V PEKAIKL NDF R L E+LAG AG QV+ T P+E++KI
Sbjct: 69 AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128
Query: 453 RLQVAGEI-----------------TTG---------PRVSALNVLRDLGIFGLYKGAKA 486
+LQ AG + TTG + A +LR G+ GLY+G A
Sbjct: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188
Query: 487 CFLRDIPFSAIYFPVYAHCKLLLADE-NGHVGGLNLLAAGAMAGVPAASLVTPADVIKTR 545
LRDIPFS IYFP++A+ L +E G + +G +AG AA VTP DV+KTR
Sbjct: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248
Query: 546 LQVAARA-GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTY 598
+Q + G+ YSG+ DC RK+ +EGPSAF KG R +P FG+ Y
Sbjct: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302
Score = 49.7 bits (117), Expect = 9e-06
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTA 581
L G +AG+ + V P D+ KTRLQ + G+ Y G+IDC K R EG ++G A
Sbjct: 12 LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69
Query: 582 ARVFRSSPQFGVTLVTYELLQR 603
+ +P+ + L + +R
Sbjct: 70 VNLTLVTPEKAIKLAANDFFRR 91
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 324 AESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYE 383
A A+ F G VAG++ A AV P+D++KTR+Q + +GE MY DC +K+ E
Sbjct: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275
Query: 384 GFFGLYRGLIPQLIGVAP 401
G +G + + +AP
Sbjct: 276 GPSAFMKGAGCRALVIAP 293
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 26/189 (13%)
Query: 426 LPAEVLAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALNVLRDLGIFGLYKG 483
+ A+++ GG AG V P+++ K RL Q + G + R G FG+Y+G
Sbjct: 8 ITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRG 67
Query: 484 AKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-LAAGAMAGVPAASLVTPADVI 542
A P AI + LL E+G L + + AG AG+ + P +++
Sbjct: 68 AAVNLTLVTPEKAIKLAANDFFRRLLM-EDGMQRNLKMEMLAGCGAGMCQVVVTCPMEML 126
Query: 543 KTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPSAFWKGT 580
K +LQ A R ++ +G R+ +LR +G + ++G
Sbjct: 127 KIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGL 186
Query: 581 AARVFRSSP 589
A + R P
Sbjct: 187 GATLLRDIP 195
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 126 bits (316), Expect = 8e-29
Identities = 84/292 (28%), Positives = 128/292 (43%), Gaps = 26/292 (8%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
F G ++GA+G +P D VK R+Q Q Y+ DC K+ R+E G +
Sbjct: 6 FVAGWISGALGLVLGHPFDTVKVRLQTQT---------TYRGIVDCMVKIYRHESLLGFF 56
Query: 390 RGLIPQLIGVAPEKAIKLTVND-----FVRDKFTRRDGSVPLPAEVLAGGCAGGS-QVIF 443
+G+ + +A ++ V R P + GC GG Q
Sbjct: 57 KGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYC 116
Query: 444 TNPLEIVKIRLQVAGEITT----------GPRVSALNVLRDLGIFGLYKGAKACFLRDIP 493
P +++K+RLQ E GP A ++ R+ G GL++GA A LRD P
Sbjct: 117 LAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTP 176
Query: 494 FSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAG 553
IYF Y E + +L AG AG+ + TP D+IK+R+Q+
Sbjct: 177 TVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDG-LR 235
Query: 554 QTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWF 605
+ Y G++DC +R+EG F++G R+ P VT ++YE L RW+
Sbjct: 236 RRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWW 287
Score = 69.7 bits (169), Expect = 8e-12
Identities = 55/204 (26%), Positives = 87/204 (42%), Gaps = 20/204 (9%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACF 488
E +AG +G ++ +P + VK+RLQ G + + R + G +KG
Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQ-TTYRGIVDCMVKIYRHESLLGFFKGMSFPI 63
Query: 489 LRDIPFSAIYFPVYAHCKLLLADENGH------VGGLNLLAAGAMAGVPAASLVTPADVI 542
+++ F VY++ L+L + +++ AG G A + P D+I
Sbjct: 64 ASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLI 123
Query: 543 KTRLQ----VAARAGQ--TTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLV 596
K RLQ A+ G Y G + C I REEGP ++G A R +P G+ +
Sbjct: 124 KVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFI 183
Query: 597 TYELLQRWFYIDFGGLKPAGSEPT 620
TYE L R + P G P+
Sbjct: 184 TYEGLCRQY-------TPEGQNPS 200
Score = 35.8 bits (81), Expect = 0.13
Identities = 33/129 (25%), Positives = 48/129 (37%), Gaps = 16/129 (12%)
Query: 277 LYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVA 336
L+ + LTL D + G L RQ +P P SA G A
Sbjct: 163 LFRGAWALTLRDTPTV-----GIYFITYEGLCRQYTPEGQNP------SSATVLVAGGFA 211
Query: 337 GAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQL 396
G A P+D++K+RMQ + +Y+ DC +R EG +RG+
Sbjct: 212 GIASWVAATPLDMIKSRMQMDG-----LRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINS 266
Query: 397 IGVAPEKAI 405
P A+
Sbjct: 267 ARAFPVNAV 275
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 118 bits (295), Expect = 2e-26
Identities = 87/292 (29%), Positives = 131/292 (44%), Gaps = 17/292 (5%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G VA AV TAV PI+ VK +Q Q S + E YK DC ++ R +GFF +RG
Sbjct: 27 GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP-----LPAEVLAGGCAGGSQVIFTNPL 447
+ +I P +A+ D + F A + +GG AG + + PL
Sbjct: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146
Query: 448 EIVKIRLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIPFSAIYF 499
+ + RL V +I GP L D GI GLY+G I + A YF
Sbjct: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204
Query: 500 PVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSG 559
Y K LL ++ A + + L P D ++ R+ + + + Y G
Sbjct: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVT-TCSGILSYPFDTVRRRMMMQSGEAKRQYKG 263
Query: 560 VIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGG 611
+DCF KI + EG S+F++G + V R + + LV Y+ ++ +F+ID GG
Sbjct: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314
Score = 53.5 bits (127), Expect = 6e-07
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 27/177 (15%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----NVLRDLGIFGL 480
++LAGG A P+E VK+ LQV + +I+ R + + R+ G F
Sbjct: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82
Query: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-----------LAAGAMAG 529
++G A +R P A+ F K L + G+N LA+G AG
Sbjct: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLF------MSGVNKEKQFWRWFLANLASGGAAG 136
Query: 530 VPAASLVTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPSAFWKGTAARV 584
+ +V P D +TRL V G + + G+ DC KI + +G + ++G V
Sbjct: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 117 bits (292), Expect = 5e-26
Identities = 89/286 (31%), Positives = 140/286 (48%), Gaps = 23/286 (8%)
Query: 335 VAGAVGATAV----YPIDLVKTRMQNQRGSGSVVGE-LMYKNSFDCFKKVLRYEGFFGLY 389
+AG G + +P+D VK R+Q Q S+ G+ MY +FDCF+K L EG GLY
Sbjct: 15 LAGGFGGVCLVFVGHPLDTVKVRLQTQ--PPSLPGQPPMYSGTFDCFRKTLFREGITGLY 72
Query: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFT----N 445
RG+ +IGV P A+ + + V ++ A G G +FT
Sbjct: 73 RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSG---VFTTGIMT 129
Query: 446 PLEIVKIRLQV---AGEIT-TGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPV 501
P E +K LQ+ +GE TG A + ++ GI G+YKG +RD+P S +YF
Sbjct: 130 PGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMT 189
Query: 502 YAHCKLLLADENGHVGGLN---LLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYS 558
Y K + E V L+ +L AG +AG+ ++ P DV+K+R Q A +
Sbjct: 190 YEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYP--N 247
Query: 559 GVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
G D R+++R+EG ++ +KG A + R+ P + +E+ ++
Sbjct: 248 GFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293
Score = 87.4 bits (215), Expect = 4e-17
Identities = 62/184 (33%), Positives = 89/184 (48%), Gaps = 8/184 (4%)
Query: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG--PRVSAL-----NVLRDLGIFGLYK 482
+LAGG G V +PL+ VK+RLQ G P S L GI GLY+
Sbjct: 14 LLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR 73
Query: 483 GAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGL-NLLAAGAMAGVPAASLVTPADV 541
G A + P A+ F + K L V L AAG ++GV ++TP +
Sbjct: 74 GMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGER 133
Query: 542 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELL 601
IK LQ+ A +G++ Y+G +DC +K+ +E G +KGT + R P G+ +TYE L
Sbjct: 134 IKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWL 193
Query: 602 QRWF 605
+ F
Sbjct: 194 KNIF 197
Score = 53.9 bits (128), Expect = 5e-07
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 509 LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQV--AARAGQ-TTYSGVIDCFR 565
+AD+ + L L AG GV + P D +K RLQ + GQ YSG DCFR
Sbjct: 1 MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFR 60
Query: 566 KILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600
K L EG + ++G AA + +P F V + L
Sbjct: 61 KTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGL 95
Score = 31.2 bits (69), Expect = 3.3
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSF-DCFKKVLRYEGFFGLYRG 391
G +AG P D++K+R Q Y N F D ++++R EG LY+G
Sbjct: 216 GGIAGIFNWAVAIPPDVLKSRFQTAPPG-------KYPNGFRDVLRELIRDEGVTSLYKG 268
Query: 392 LIPQLIGVAPEKA 404
+I P A
Sbjct: 269 FNAVMIRAFPANA 281
>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
Length = 308
Score = 116 bits (290), Expect = 8e-26
Identities = 94/310 (30%), Positives = 132/310 (42%), Gaps = 47/310 (15%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
F G++ G G YP+D VK R+Q E Y + C + E +G Y
Sbjct: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53
Query: 390 RGLIPQLIGVAPEKAIKL-----TVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGS-QVIF 443
RGL + V+ ++ + R ++ D P A++ GCA G +V
Sbjct: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112
Query: 444 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALNVLRD 474
T+P E+ K+RLQ +G + GP V R+
Sbjct: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172
Query: 475 LGIFGLYKGAKACFLRDIPFSAIYFPVYAH-CKLLLADENGHVGGLNLLAAGAMAGVPAA 533
G+ GLYKG+ A LRD A YF YA C+ L + +L AG AGV A
Sbjct: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAW 232
Query: 534 SLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGV 593
++ TP DVIK+RLQ + GQ Y G++ C +REEGP +KG R+ P V
Sbjct: 233 AVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
Query: 594 TLVTYELLQR 603
V YE + R
Sbjct: 292 VFVAYEAVLR 301
Score = 60.8 bits (146), Expect = 4e-09
Identities = 53/223 (23%), Positives = 88/223 (39%), Gaps = 48/223 (21%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-NVLRDL----GIFGLYKG 483
+ +AG G V PL+ VK+R+Q T P+ + + + +RD ++G Y+G
Sbjct: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55
Query: 484 AKACFLRDIPFSAIYFPVYAHC-----KLLLADENGHVGGLNLLAAGAMAGVPAASLVTP 538
S++ F Y HC +L + + ++ +G +G+ L +P
Sbjct: 56 LSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSP 115
Query: 539 ADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEGP 573
+V K RLQ +A + Y G + C + REEG
Sbjct: 116 TEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGL 175
Query: 574 SAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAG 616
+KG++A V R F ++Y +L W L PAG
Sbjct: 176 CGLYKGSSALVLRDGHSFATYFLSYAVLCEW-------LSPAG 211
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 115 bits (287), Expect = 2e-25
Identities = 83/293 (28%), Positives = 140/293 (47%), Gaps = 19/293 (6%)
Query: 323 IAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRY 382
+ E++ + G AG V ++P+D+VKTR Q QR YK+ D F+ + +
Sbjct: 10 VREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQR---CATDPNSYKSLVDSFRMIFQM 66
Query: 383 EGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEV---LAGGCAGGS 439
EG FG Y+G++P ++ P++A+K F +++ + G V L + +AG +G +
Sbjct: 67 EGLFGFYKGILPPILAETPKRAVKF----FTFEQYKKLLGYVSLSPALTFAIAGLGSGLT 122
Query: 440 QVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL------GIFGLYKGAKACFLRDIP 493
+ I NP E+VK+ LQ A T + S + R + G+ GL KG A R
Sbjct: 123 EAIVVNPFEVVKVGLQ-ANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGV 181
Query: 494 FSAIYFPVYAHCK-LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARA 552
F+ +YF Y + K ++ +++ + G ++G A+ + P DV K+R+Q
Sbjct: 182 FNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPV 241
Query: 553 -GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
G+ Y + +EEG A +KG ++ R P V L+ YE W
Sbjct: 242 PGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSW 294
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 115 bits (287), Expect = 2e-25
Identities = 88/312 (28%), Positives = 132/312 (42%), Gaps = 23/312 (7%)
Query: 327 AYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFF 386
A F G G G +P D VK R+Q Q V + Y+ + CFK +++ E
Sbjct: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56
Query: 387 GLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNP 446
GLY+GL L+G+ A+ V + R G + LAG AG Q + P
Sbjct: 57 GLYKGLGSPLMGLTFINALVFGV----QGNTLRALGHDSPLNQFLAGAAAGAIQCVICCP 112
Query: 447 LEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSAIYFPVY 502
+E+ K RLQ+ +L+ L + G+ G+ +G + LR+ P +YF Y
Sbjct: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172
Query: 503 AHCKLLLADENG-HVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVI 561
L E G + LL AG +G+ + P DV+K+RLQ G Y G++
Sbjct: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232
Query: 562 DCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTP 621
DC + R EG F +G A+ + R+ P T T ++ + G E P
Sbjct: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTY---------ARGEEAGP 283
Query: 622 KSRIADLPPANP 633
+ PA P
Sbjct: 284 EGEAVPAAPAGP 295
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 114 bits (285), Expect = 3e-25
Identities = 88/295 (29%), Positives = 135/295 (45%), Gaps = 29/295 (9%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
F G VA AV TAV PI+ VK +Q Q S + E YK DC ++ + +GF +
Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
Query: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--------LPAEVLAGGCAGGSQV 441
RG + +I P +A+ D + F G V + +GG AG + +
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFL---GGVDRHKQFWRYFAGNLASGGAAGATSL 128
Query: 442 IFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIP 493
F PL+ + RL A ++ G + L D G+ GLY+G I
Sbjct: 129 CFVYPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
Query: 494 FSAIYFPVYAHCKLLLAD-ENGHVGGLNLLAAGAMAGVPAASLVT-PADVIKTR--LQVA 549
+ A YF VY K +L D +N H+ ++A A A LV+ P D ++ R +Q
Sbjct: 187 YRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTA---VAGLVSYPFDTVRRRMMMQSG 243
Query: 550 ARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
+ Y+G +DC+RKI ++EG AF+KG + V R LV Y+ ++++
Sbjct: 244 RKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGG-AFVLVLYDEIKKY 297
Score = 48.5 bits (114), Expect = 2e-05
Identities = 46/172 (26%), Positives = 70/172 (40%), Gaps = 27/172 (15%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALNVLRDLGIFGL 480
+ LAGG A P+E VK+ LQV A + G + + ++ G
Sbjct: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70
Query: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-----------LAAGAMAG 529
++G A +R P A+ F K L +GG++ LA+G AG
Sbjct: 71 WRGNLANVIRYFPTQALNFAFKDKYKQLF------LGGVDRHKQFWRYFAGNLASGGAAG 124
Query: 530 VPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPSAFWKG 579
+ V P D +TRL V A Q + G+ DC KI + +G ++G
Sbjct: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQG 176
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 110 bits (276), Expect = 3e-24
Identities = 88/301 (29%), Positives = 135/301 (44%), Gaps = 27/301 (8%)
Query: 322 QIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLR 381
Q A F G +A A+ TAV PI+ VK +Q Q S + + YK DC ++ +
Sbjct: 4 QAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPK 63
Query: 382 YEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--------LPAEVLAG 433
+G +RG + +I P +A+ D + F G V + +G
Sbjct: 64 EQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL---GGVDKHTQFWRYFAGNLASG 120
Query: 434 GCAGGSQVIFTNPLEIVKIRLQV-AGEITTGPRVSAL-----NVLRDLGIFGLYKGAKAC 487
G AG + + F PL+ + RL G+ T L + + GI GLY+G
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVS 180
Query: 488 FLRDIPFSAIYFPVYAHCKLLLAD-ENGHVGGLNLLA--AGAMAGVPAASLVTPADVIKT 544
I + A YF VY K +L D +N H+ ++A A+AGV + P D ++
Sbjct: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGV----VSYPFDTVRR 236
Query: 545 R--LQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
R +Q + Y+G +DC+RKI R+EG AF+KG + V R LV Y+ L+
Sbjct: 237 RMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGG-AFVLVLYDELK 295
Query: 603 R 603
+
Sbjct: 296 K 296
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 108 bits (271), Expect = 1e-23
Identities = 86/304 (28%), Positives = 136/304 (44%), Gaps = 44/304 (14%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQR-----------------GSGSVVGELMYKNSFDC 375
G G VGA P++++KTR+Q+ R G+G V + F
Sbjct: 18 GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77
Query: 376 FKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGC 435
K +L EG L+RGL P L+GVAP +A+ +++F + +P +
Sbjct: 78 LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN----GIFVPNSNIVHIF 133
Query: 436 AGGSQVIFTN----PLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKAC 487
+ GS TN P+ +VK R+Q+ ++ +++ L R + GI G Y+G A
Sbjct: 134 SAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTAS 193
Query: 488 FLRDIPFSAIYFPVYAHCKLLLAD----------ENGHVGGLNLLAAGAMAGVPAASLVT 537
+ I + I F +Y K L + E L+AA A++ A+ +
Sbjct: 194 YA-GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAY 252
Query: 538 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVT 597
P +VI+TRL R T Y + R + REEG AF++G A++ R P + L T
Sbjct: 253 PHEVIRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLST 308
Query: 598 YELL 601
YEL+
Sbjct: 309 YELI 312
Score = 56.6 bits (135), Expect = 7e-08
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 34/204 (16%)
Query: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 464
+ AGGC G IFT PLE++K RLQ ++G +T G
Sbjct: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
Query: 465 RVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENG----HVGGLN 520
++L G L++G + P A+YF Y+ K NG + ++
Sbjct: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAK---EQFNGIFVPNSNIVH 131
Query: 521 LLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGT 580
+ +AG+ A + SL+ P ++KTR+Q+ + + + C R + + EG F++G
Sbjct: 132 IFSAGSAAFI-TNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
Query: 581 AARVFRSSPQFGVTLVTYELLQRW 604
A + + + YE L+++
Sbjct: 191 TAS-YAGISETIICFAIYESLKKY 213
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 24/196 (12%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQ-NQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388
F+ GS A + + + PI +VKTRMQ Q+ GS N+ C + V + EG G
Sbjct: 133 FSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRGS-----KQMNTLQCARYVYQTEGIRGF 186
Query: 389 YRGLIPQLIGVAPEK---AIKLTVNDFVRDK--FTRRDGSVP--------LPAEVLAGGC 435
YRGL G++ AI ++ ++++ + +G+ + A L+ GC
Sbjct: 187 YRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGC 246
Query: 436 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFS 495
A P E+++ RL+ G +A V R+ G Y+G A +R IP +
Sbjct: 247 AS----CIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNT 302
Query: 496 AIYFPVYAHCKLLLAD 511
AI Y LL D
Sbjct: 303 AIVLSTYELIVYLLED 318
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 108 bits (270), Expect = 2e-23
Identities = 81/289 (28%), Positives = 131/289 (45%), Gaps = 17/289 (5%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
F G VA A+ TAV PI+ VK +Q Q S + + YK DC ++ + +G +
Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
Query: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKF-----TRRDGSVPLPAEVLAGGCAGGSQVIFT 444
RG + +I P +A+ D + F R + + +GG AG + + F
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFV 131
Query: 445 NPLEIVKIRLQV------AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIY 498
PL+ + RL A G + + + GI GLY+G I + A Y
Sbjct: 132 YPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAY 191
Query: 499 FPVYAHCKLLLAD-ENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTR--LQVAARAGQT 555
F +Y K +L D +N H+ ++ + A + V A P D ++ R +Q +
Sbjct: 192 FGIYDTAKGMLPDPKNTHI-VISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGTDI 249
Query: 556 TYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
Y+G +DC+RKI R+EG AF+KG + V R LV Y+ ++++
Sbjct: 250 MYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGG-AFVLVLYDEIKKY 297
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 27/180 (15%)
Query: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----NVL 472
D +V + LAGG A P+E VK+ LQV + +IT + + +
Sbjct: 3 DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
Query: 473 RDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL----------- 521
++ G+ ++G A +R P A+ F K + +GG++
Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIF------LGGVDKRTQFWLYFAGN 116
Query: 522 LAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPSAFWKG 579
LA+G AG + V P D +TRL V + + G+ DC KI + +G ++G
Sbjct: 117 LASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQG 176
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 104 bits (259), Expect = 3e-22
Identities = 79/281 (28%), Positives = 127/281 (45%), Gaps = 8/281 (2%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQ-RGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388
F G +A +PIDL KTR+Q Q + + + E+ Y+ ++ R EG L
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 389 YRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLE 448
Y G+ P ++ A IK+ ++ F R LP V+ G +G NP +
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTD 128
Query: 449 IVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK- 506
++KIR+Q G + + +N+ + G GL+KG R + PVY K
Sbjct: 129 VLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKK 188
Query: 507 -LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTT-YSGVID 562
L+L+ G + L++ G+ A P DV++TR+ Q R G+ + Y+G +D
Sbjct: 189 HLILSGLMGDTVYTHFLSS-FTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLD 247
Query: 563 CFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
C + + EG A +KG R P + VTYE L++
Sbjct: 248 CLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 50.4 bits (119), Expect = 5e-06
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 21/187 (11%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGS--GSVVGELMYKNSFDCFKKVLRYEGFFGLYR 390
G ++G + +T P D++K RMQ Q + G ++G M + + EG GL++
Sbjct: 113 GILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFM---------NIYQQEGTRGLWK 163
Query: 391 GLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSV--PLPAEVLAGGCAGGSQVIFTNPLE 448
G+ A ++L V D + K G + + L+ G + + +NP++
Sbjct: 164 GVSLTAQRAAIVVGVELPVYDITK-KHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVD 222
Query: 449 IVKIRLQVAGEIT-------TGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPV 501
+V+ R+ + TG L ++ G F LYKG +LR P++ I+F
Sbjct: 223 VVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVT 282
Query: 502 YAHCKLL 508
Y K L
Sbjct: 283 YEQLKKL 289
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 525 GAMAGVPAASLVTPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPSAFWKG 579
G +A + A P D+ KTRLQ+ A+ + Y G++ +I REEG A + G
Sbjct: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
Query: 580 TAARVFRSSPQFGVTLVTYELLQRWF 605
A + R + + + TY+ L+R F
Sbjct: 72 IAPAMLRQASYGTIKIGTYQSLKRLF 97
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 104 bits (259), Expect = 3e-22
Identities = 85/285 (29%), Positives = 131/285 (45%), Gaps = 41/285 (14%)
Query: 343 AVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402
+VYP L++TR+Q Q+G +Y +FD F K+LR +G GLYRG + +
Sbjct: 34 SVYPFTLIRTRLQVQKGKS------LYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87
Query: 403 KAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI---------- 452
+ +T + R KF ++AGG A T P+++V
Sbjct: 88 QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145
Query: 453 --RLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIPFSAIYFPVY 502
R QV G G V A +D+ G+ G Y+G A L IP SA+++P Y
Sbjct: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
Query: 503 ----AHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYS 558
L E H+ + +G +A A+ L P DVI+TR+QV + +
Sbjct: 205 HFYAEQLSYLCPKECPHI--VFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------N 256
Query: 559 GVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
+I FR+++ EEGP KG +AR+ ++P V +V YE L++
Sbjct: 257 SIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
Score = 33.5 bits (75), Expect = 0.66
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 10/73 (13%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G +A A + P+D+++TR+Q + G S++ F++++ EG +GL +GL
Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVE-GKNSII---------LTFRQLMAEEGPWGLMKGL 278
Query: 393 IPQLIGVAPEKAI 405
++I P +
Sbjct: 279 SARIISATPSTIV 291
>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
sapiens]
Length = 246
Score = 102 bits (255), Expect = 9e-22
Identities = 69/244 (28%), Positives = 107/244 (43%), Gaps = 17/244 (6%)
Query: 378 KVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVND-----FVRDKFTRRDGSVPLPAEVLA 432
K+ R+E G ++G+ + +A ++ V R P +
Sbjct: 3 KIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFL 62
Query: 433 GGCAGGS-QVIFTNPLEIVKIRLQVAGEITT----------GPRVSALNVLRDLGIFGLY 481
GC GG Q P +++K+RLQ E GP A ++ R+ G GL+
Sbjct: 63 AGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLF 122
Query: 482 KGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADV 541
+GA A LRD P IYF Y E + +L AG AG+ + TP D+
Sbjct: 123 RGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDM 182
Query: 542 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELL 601
IK+R+Q+ + Y G++DC +R+EG F++G R+ P VT ++YE L
Sbjct: 183 IKSRMQMDG-LRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 241
Query: 602 QRWF 605
RW+
Sbjct: 242 LRWW 245
Score = 61.6 bits (148), Expect = 2e-09
Identities = 50/181 (27%), Positives = 81/181 (44%), Gaps = 7/181 (3%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGE--LMYKNSFDCFKKVLRYEGFFG 387
F G G + A + P DL+K R+QNQ + G Y+ C + R EG G
Sbjct: 61 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120
Query: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVL-AGGCAGGSQVIFTNP 446
L+RG + P I + + ++T +G P A VL AGG AG + + P
Sbjct: 121 LFRGAWALTLRDTPTVGIYFITYEGLCRQYT-PEGQNPSSATVLVAGGFAGIASWVAATP 179
Query: 447 LEIVKIRLQVAG---EITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYA 503
L+++K R+Q+ G + G ++ +R G+ ++G R P +A+ F Y
Sbjct: 180 LDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYE 239
Query: 504 H 504
+
Sbjct: 240 Y 240
Score = 35.8 bits (81), Expect = 0.13
Identities = 33/129 (25%), Positives = 48/129 (37%), Gaps = 16/129 (12%)
Query: 277 LYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVA 336
L+ + LTL D + G L RQ +P P SA G A
Sbjct: 121 LFRGAWALTLRDTPTV-----GIYFITYEGLCRQYTPEGQNP------SSATVLVAGGFA 169
Query: 337 GAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQL 396
G A P+D++K+RMQ + +Y+ DC +R EG +RG+
Sbjct: 170 GIASWVAATPLDMIKSRMQMDG-----LRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINS 224
Query: 397 IGVAPEKAI 405
P A+
Sbjct: 225 ARAFPVNAV 233
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 102 bits (254), Expect = 1e-21
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 5/183 (2%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--LNVLRDLGIFGLYKGAKA 486
++LAGG AG T PL+ +KI +QV G + + ++++ GI L++G
Sbjct: 197 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 256
Query: 487 CFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL 546
++ P +A+ F Y K LL +E +G +G+MAG A + + P +V+KTRL
Sbjct: 257 NVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRL 316
Query: 547 QVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFY 606
V + GQ YSG+ DC +KIL+ EG AF+KG + P G+ L YELL+ ++
Sbjct: 317 AVG-KTGQ--YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373
Query: 607 IDF 609
+F
Sbjct: 374 DNF 376
Score = 98.2 bits (243), Expect = 2e-20
Identities = 72/277 (25%), Positives = 126/277 (45%), Gaps = 13/277 (4%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G +AGAV T+ P+D +K MQ + N F F+++++ G L+RG
Sbjct: 201 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM------NIFGGFRQMVKEGGIRSLWRGN 254
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
+I +APE A+K + + T + ++G AG + F P+E++K
Sbjct: 255 GTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKT 314
Query: 453 RLQV--AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL-- 508
RL V G+ +G A +L+ G+ YKG L IP++ I VY K
Sbjct: 315 RLAVGKTGQY-SGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373
Query: 509 --LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRK 566
A ++ + G + LL GA++ P +++TR+Q A + ++ FR+
Sbjct: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 433
Query: 567 ILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
I+ +EG ++G + P G++ V YE +++
Sbjct: 434 IISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 92.4 bits (228), Expect = 1e-18
Identities = 110/469 (23%), Positives = 200/469 (42%), Gaps = 78/469 (16%)
Query: 95 FQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGH-NRKKHLNYTEFTQF 153
FQ D++G+G V ++E + + IP D E G N+ L++ EF ++
Sbjct: 28 FQALDRNGDGVVDIGELQE----GLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKY 83
Query: 154 LQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIR---SHMLTPFVEENLVSAAGGSI 210
L++ + + + AF DK+ G I + + T+ S + +++ ++
Sbjct: 84 LKDHE-KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTV 142
Query: 211 SHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQ-------- 262
YF FN + + E++R + D +EF + + GQ
Sbjct: 143 DWNEWRDYF-LFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAG 201
Query: 263 ----------VTPLE-IDILYQL----ADLYNASG---------------RLTLADIERI 292
PL+ + I+ Q+ +D N G R ++ +I
Sbjct: 202 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKI 261
Query: 293 APLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKT 352
AP E A+ + E ++ G+ I + RF GS+AGA T +YP++++KT
Sbjct: 262 AP--ETAVKFWAYEQYKKLLTEEGQKIG-----TFERFISGSMAGATAQTFIYPMEVMKT 314
Query: 353 RMQNQRGSGSVVGEL-MYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVND 411
R+ VG+ Y +DC KK+L++EG Y+G +P L+G+ P I L V +
Sbjct: 315 RL--------AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE 366
Query: 412 FVR----DKFTRRDGSVPLPAEVLAGGCAGGSQV---IFTNPLEIVKIRLQVAGEITTGP 464
++ D F + + P ++ GC S + + PL +V+ R+Q + P
Sbjct: 367 LLKSYWLDNFAKDSVN---PGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSP 423
Query: 465 RVSALNVLRDL----GIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL 509
+++ + + R + GI GLY+G F++ +P I + VY + K L
Sbjct: 424 QLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 102 bits (254), Expect = 1e-21
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 5/183 (2%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--LNVLRDLGIFGLYKGAKA 486
++LAGG AG T PL+ +KI +QV G + + ++++ GI L++G
Sbjct: 178 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 237
Query: 487 CFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL 546
++ P +A+ F Y K LL +E +G +G+MAG A + + P +V+KTRL
Sbjct: 238 NVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRL 297
Query: 547 QVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFY 606
V + GQ YSG+ DC +KIL+ EG AF+KG + P G+ L YELL+ ++
Sbjct: 298 AVG-KTGQ--YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
Query: 607 IDF 609
+F
Sbjct: 355 DNF 357
Score = 98.2 bits (243), Expect = 2e-20
Identities = 72/277 (25%), Positives = 126/277 (45%), Gaps = 13/277 (4%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G +AGAV T+ P+D +K MQ + N F F+++++ G L+RG
Sbjct: 182 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM------NIFGGFRQMVKEGGIRSLWRGN 235
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
+I +APE A+K + + T + ++G AG + F P+E++K
Sbjct: 236 GTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKT 295
Query: 453 RLQV--AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL-- 508
RL V G+ +G A +L+ G+ YKG L IP++ I VY K
Sbjct: 296 RLAVGKTGQY-SGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
Query: 509 --LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRK 566
A ++ + G + LL GA++ P +++TR+Q A + ++ FR+
Sbjct: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 414
Query: 567 ILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
I+ +EG ++G + P G++ V YE +++
Sbjct: 415 IISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 90.9 bits (224), Expect = 3e-18
Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 23/193 (11%)
Query: 329 RFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGEL-MYKNSFDCFKKVLRYEGFFG 387
RF GS+AGA T +YP++++KTR+ VG+ Y +DC KK+L++EG
Sbjct: 272 RFISGSMAGATAQTFIYPMEVMKTRL--------AVGKTGQYSGIYDCAKKILKHEGLGA 323
Query: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVR----DKFTRRDGSVPLPAEVLAGGCAGGSQV-- 441
Y+G +P L+G+ P I L V + ++ D F + + P ++ GC S
Sbjct: 324 FYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN---PGVMVLLGCGALSSTCG 380
Query: 442 -IFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSA 496
+ + PL +V+ R+Q + P+++ + + R + GI GLY+G F++ +P
Sbjct: 381 QLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG 440
Query: 497 IYFPVYAHCKLLL 509
I + VY + K L
Sbjct: 441 ISYVVYENMKQTL 453
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 101 bits (252), Expect = 2e-21
Identities = 77/298 (25%), Positives = 130/298 (43%), Gaps = 34/298 (11%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGS------------GSVVGELMYKNSFDCFKKVL 380
G G VGA P+++VKTR+Q+ + G+ V ++ C K +L
Sbjct: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72
Query: 381 RYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQ 440
EG L+RGL P L+GVAP +AI ++K +++ AG +
Sbjct: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132
Query: 441 VIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSA 496
+ TNP+ ++K RLQ+ R+ A +R + G+ G Y+G A + I +
Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191
Query: 497 IYFPVYAHCKLLLAD-------ENGHVG------GLNLLAAGAMAGVPAASLVTPADVIK 543
I+F +Y K L + EN + ++ A A + A ++ P +V++
Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVR 251
Query: 544 TRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELL 601
TRL R T Y +++EEG + ++G + R P + + TYEL+
Sbjct: 252 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 305
Score = 75.5 bits (184), Expect = 2e-13
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Query: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 469
+ AGGC G I T PLE+VK RLQ +AG ++ GP
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 470 NVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAG 529
+L G L++G + P AIYF Y++CK L D + + AMAG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 530 VPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSP 589
A + P +IKTRLQ+ AR G +C RK+ + +G F++G +A +
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS-YAGIS 188
Query: 590 QFGVTLVTYELLQR 603
+ + V YE +++
Sbjct: 189 ETVIHFVIYESIKQ 202
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 101 bits (252), Expect = 2e-21
Identities = 78/280 (27%), Positives = 124/280 (44%), Gaps = 7/280 (2%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGS-GSVVGELMYKNSFDCFKKVLRYEGFFGL 388
F G +A V +P+DL KTR+Q Q S + E+ Y+ F ++ + EG L
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 389 YRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLE 448
Y G+ P L+ A IK+ + ++ F R L ++ G +G NP +
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163
Query: 449 IVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK- 506
++KIR+Q G + G + S +++ + G GL++G R + PVY K
Sbjct: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223
Query: 507 -LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 563
L+L+ G L + G+ A P DV++TR+ Q A Y G +D
Sbjct: 224 HLILSGMMGDT-ILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282
Query: 564 FRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
K+ + EG A +KG R P + +TYE L+R
Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 16/184 (8%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G V+G + +T P D++K RMQ Q G L + F + + EG GL+RG+
Sbjct: 148 GVVSGVISSTIANPTDVLKIRMQAQ-------GSLFQGSMIGSFIDIYQQEGTRGLWRGV 200
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRD--GSVPLPAEVLAGGCAGGSQVIFTNPLEIV 450
+P A ++L V D + G L V + C G + + +NP+++V
Sbjct: 201 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC-GLAGALASNPVDVV 259
Query: 451 KIRLQ----VAGEITT--GPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAH 504
+ R+ + G + G L + + G F LYKG +LR P++ I+F Y
Sbjct: 260 RTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ 319
Query: 505 CKLL 508
K L
Sbjct: 320 LKRL 323
Score = 46.6 bits (109), Expect = 8e-05
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 10/134 (7%)
Query: 479 GLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL--LAAGAMAGVPAASLV 536
G++ G FLR + F+ V H K + GLN G +A + A
Sbjct: 2 GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHE--MSGLNWKPFVYGGLASIVAEFGT 58
Query: 537 TPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQF 591
P D+ KTRLQV AR + Y G+ +I +EEG A + G A + R +
Sbjct: 59 FPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYG 118
Query: 592 GVTLVTYELLQRWF 605
+ + Y+ L+R F
Sbjct: 119 TIKIGIYQSLKRLF 132
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 101 bits (252), Expect = 2e-21
Identities = 78/280 (27%), Positives = 124/280 (44%), Gaps = 7/280 (2%)
Query: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGS-GSVVGELMYKNSFDCFKKVLRYEGFFGL 388
F G +A V +P+DL KTR+Q Q S + E+ Y+ F ++ + EG L
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 389 YRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLE 448
Y G+ P L+ A IK+ + ++ F R L ++ G +G NP +
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 160
Query: 449 IVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK- 506
++KIR+Q G + G + S +++ + G GL++G R + PVY K
Sbjct: 161 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 220
Query: 507 -LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 563
L+L+ G L + G+ A P DV++TR+ Q A Y G +D
Sbjct: 221 HLILSGMMGDT-ILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 279
Query: 564 FRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
K+ + EG A +KG R P + +TYE L+R
Sbjct: 280 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 16/184 (8%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G V+G + +T P D++K RMQ Q G L + F + + EG GL+RG+
Sbjct: 145 GVVSGVISSTIANPTDVLKIRMQAQ-------GSLFQGSMIGSFIDIYQQEGTRGLWRGV 197
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRD--GSVPLPAEVLAGGCAGGSQVIFTNPLEIV 450
+P A ++L V D + G L V + C G + + +NP+++V
Sbjct: 198 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC-GLAGALASNPVDVV 256
Query: 451 KIRLQ----VAGEITT--GPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAH 504
+ R+ + G + G L + + G F LYKG +LR P++ I+F Y
Sbjct: 257 RTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ 316
Query: 505 CKLL 508
K L
Sbjct: 317 LKRL 320
Score = 43.1 bits (100), Expect = 8e-04
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 13/134 (9%)
Query: 479 GLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL--LAAGAMAGVPAASLV 536
G++ G FLR + F A + + GLN G +A + A
Sbjct: 2 GIFPGIILIFLR------VKFATAAVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGT 55
Query: 537 TPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQF 591
P D+ KTRLQV AR + Y G+ +I +EEG A + G A + R +
Sbjct: 56 FPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYG 115
Query: 592 GVTLVTYELLQRWF 605
+ + Y+ L+R F
Sbjct: 116 TIKIGIYQSLKRLF 129
>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
Length = 274
Score = 100 bits (250), Expect = 3e-21
Identities = 77/254 (30%), Positives = 112/254 (44%), Gaps = 23/254 (9%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G VAG ++P+D +KTR+Q+ +G F K GF G+Y G+
Sbjct: 13 GGVAGVSVDLILFPLDTIKTRLQSPQG----------------FNKA---GGFHGIYAGV 53
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTN-PLEIVK 451
IG P A ++V+ S P + + AG P E+VK
Sbjct: 54 PSAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVK 113
Query: 452 IRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLAD 511
R QV+ T S N+L + GI GLY+G K+ LR+IPFS + FP++ K L +
Sbjct: 114 QRAQVSASTRTFQIFS--NILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSW 171
Query: 512 ENGH-VGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILRE 570
H V GA AG AA++ TP DV KTR+ +A T V+ + R
Sbjct: 172 RQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTADGNVLSVLHGVWRS 231
Query: 571 EGPSAFWKGTAARV 584
+G + + G R+
Sbjct: 232 QGLAGLFAGVFPRM 245
Score = 61.2 bits (147), Expect = 3e-09
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 18/176 (10%)
Query: 428 AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKAC 487
A ++AGG AG S + PL+ +K RLQ S + G G+Y G +
Sbjct: 8 AALVAGGVAGVSVDLILFPLDTIKTRLQ-----------SPQGFNKAGGFHGIYAGVPSA 56
Query: 488 FLRDIPFSAIYFPVYAHCKLLL-ADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL 546
+ P +A +F Y + K L AD + ++ + + A + V A + P++V+K R
Sbjct: 57 AIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRA 116
Query: 547 QVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
QV+A + F IL EEG ++G + V R P V +E L+
Sbjct: 117 QVSAS------TRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLK 166
Score = 35.4 bits (80), Expect = 0.17
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 320 WLQ--IAESAYRFTLGSVAGAVGATAVYPIDLVKTR-MQNQRGSGSVVGELMYKNSFDCF 376
W Q + +S G+ AG A P+D+ KTR M + GS + G N
Sbjct: 171 WRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTADG-----NVLSVL 225
Query: 377 KKVLRYEGFFGLYRGLIPQLIGVA 400
V R +G GL+ G+ P++ ++
Sbjct: 226 HGVWRSQGLAGLFAGVFPRMAAIS 249
Score = 31.2 bits (69), Expect = 3.3
Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 16/89 (17%)
Query: 517 GGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAF 576
G + L AG +AGV ++ P D IKTRLQ + + G
Sbjct: 5 GFVAALVAGGVAGVSVDLILFPLDTIKTRLQSP---------------QGFNKAGGFHGI 49
Query: 577 WKGTAARVFRSSPQFGVTLVTYELLQRWF 605
+ G + S P +TYE + +WF
Sbjct: 50 YAGVPSAAIGSFPNAAAFFITYEYV-KWF 77
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 100 bits (250), Expect = 3e-21
Identities = 82/300 (27%), Positives = 132/300 (44%), Gaps = 20/300 (6%)
Query: 316 GRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDC 375
G+P + + + +F G +AG V P+DLVK RMQ G G+ E YK SF
Sbjct: 14 GKP---RTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLS-GEGAKTRE--YKTSFHA 67
Query: 376 FKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP-LPAEVLAGG 434
+L+ EG G+Y GL L+ A +L + + ++ T DG+ P + + G
Sbjct: 68 LTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGM 127
Query: 435 CAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVL-------RDLGIFGLYKGAKAC 487
AG + P E+ IR+ G + R NV R+ G+ L++G
Sbjct: 128 TAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPT 187
Query: 488 FLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLL---AAGAMAGVPAASLVTPADVIKT 544
R + +A Y+ K L D +G+ N+L A ++G+ + P D+ KT
Sbjct: 188 MARAVVVNAAQLASYSQSKQFLLD-SGYFSD-NILCHFCASMISGLVTTAASMPVDIAKT 245
Query: 545 RLQ-VAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
R+Q + G+ Y +D K++R EG + WKG R P +T + E + +
Sbjct: 246 RIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNK 305
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 100 bits (249), Expect = 4e-21
Identities = 78/276 (28%), Positives = 131/276 (47%), Gaps = 18/276 (6%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G +AG + +P + VKT++Q S Y+ DC ++ +R G GLYRGL
Sbjct: 32 GGLAGGIEICITFPTEYVKTQLQLDERSHPP----RYRGIGDCVRQTVRSHGVLGLYRGL 87
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQ-VIFTNPLEIVK 451
L G P+ A++ + +F+ + G + +L G AG ++ V+ P+E +K
Sbjct: 88 SSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIK 147
Query: 452 IRLQVAGEITTGPRVSAL-----NVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK 506
++ + + + P+ ++R+ G+ G Y+G A L+ AI F V +
Sbjct: 148 VKF-IHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLR 206
Query: 507 LLLADENGHVGGLNLLAA--GAMAGVPAASLVTPADVIKTRLQ-VAARAGQTTYSGVIDC 563
+N + L+ GA+AG + TP DVIKTR+Q + A + T+ DC
Sbjct: 207 NWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTW----DC 262
Query: 564 FRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYE 599
+IL++EG AF+KGT R+ R + V Y+
Sbjct: 263 GLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 298
Score = 75.1 bits (183), Expect = 2e-13
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 7/182 (3%)
Query: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-----NVLRDLGIFGLYKGA 484
+LAGG AGG ++ T P E VK +LQ+ E + PR + +R G+ GLY+G
Sbjct: 29 ILAGGLAGGIEICITFPTEYVKTQLQL-DERSHPPRYRGIGDCVRQTVRSHGVLGLYRGL 87
Query: 485 KACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGV-PAASLVTPADVIK 543
+ IP +A+ F ++ + D G + L G AGV A +V P + IK
Sbjct: 88 SSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIK 147
Query: 544 TRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
+ + Y G R+I+RE+G ++G A V + + L+
Sbjct: 148 VKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRN 207
Query: 604 WF 605
W+
Sbjct: 208 WY 209
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G++AGA P+D++KTRMQ Y+N++DC ++L+ EG Y+G
Sbjct: 227 GAIAGAASVFGNTPLDVIKTRMQGLEAH-------KYRNTWDCGLQILKKEGLKAFYKGT 279
Query: 393 IPQLIGVAPEKAIKLTVNDFV 413
+P+L V + AI + D V
Sbjct: 280 VPRLGRVCLDVAIVFVIYDEV 300
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 98.6 bits (244), Expect = 2e-20
Identities = 83/299 (27%), Positives = 127/299 (42%), Gaps = 37/299 (12%)
Query: 324 AESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYE 383
A + T G++AG + + +YP+D VKTRMQ S S + Y + + KK++R E
Sbjct: 43 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQ----SLSPDPKAQYTSIYGALKKIMRTE 98
Query: 384 GFFGLYRGLIPQLIGVAPEKA--------IKLTVNDFVRDKFTRRDGSVPLPAEVLAGGC 435
GF+ RG+ ++G P A +K T+ND + LA G
Sbjct: 99 GFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSH----------LANGI 148
Query: 436 AGGSQVIF----TNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRD 491
AG + NP E+VK RLQ+ V R G+ Y+ +
Sbjct: 149 AGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMN 208
Query: 492 IPFSAIYFPVYAHCKLLLADENGH--VGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVA 549
IPF +I+F Y + L N H + + +G +AG AA+ TP DV KT L
Sbjct: 209 IPFQSIHFITY---EFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ 265
Query: 550 ARAGQT------TYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
+ SG+ + FR + + G + ++KG ARV P ++ YE +
Sbjct: 266 ENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
Score = 48.1 bits (113), Expect = 3e-05
Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFW---K 578
+ AGAMAG+ S++ P D +KTR+Q + + Y+ + +KI+R EG FW +
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEG---FWRPLR 105
Query: 579 GTAARVFRSSPQFGVTLVTYELLQR 603
G + + P + YE ++R
Sbjct: 106 GVNVMIMGAGPAHAMYFACYENMKR 130
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNS--FDCFKKVLRYEGFFGLYR 390
G +AGA+ A A P+D+ KT + Q + + + S + F+ V + G G ++
Sbjct: 241 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK 300
Query: 391 GLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420
G+ ++I P AI +V +F + T+R
Sbjct: 301 GIQARVIYQMPSTAISWSVYEFFKYFLTKR 330
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 96.7 bits (239), Expect = 6e-20
Identities = 75/292 (25%), Positives = 124/292 (42%), Gaps = 28/292 (9%)
Query: 325 ESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEG 384
++A T G+ G P D +K +MQ +YK DCF K G
Sbjct: 8 QAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPD--------LYKGLTDCFLKTYAQVG 59
Query: 385 FFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEV------LAGGCAGG 438
G Y+G P L+ E ++ F + +F R+ + A++ AG A
Sbjct: 60 LRGFYKGTGPALMAYVAENSVLFMCYGFCQ-QFVRKVAGMDKQAKLSDLQTAAAGSFASA 118
Query: 439 SQVIFTNPLEIVKIRLQVAGEITTGPRVSALN---------VLRDLGIFGLYKGAKACFL 489
+ P E+VK RLQ E+ +++ + +L+ G G Y G + L
Sbjct: 119 FAALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLL 178
Query: 490 RDIPFSAIYFPVYAHCKLLLAD--ENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQ 547
+++P +F Y + A +G ++L+ +G +AG+ +V P D IK+R+Q
Sbjct: 179 QEVPGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQ 238
Query: 548 VAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYE 599
V + G+ +G I ++R EG A + G A + R+ P G V YE
Sbjct: 239 VLSMYGK--QAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYE 288
Score = 69.3 bits (168), Expect = 1e-11
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 19/190 (10%)
Query: 431 LAGGCAGGSQVIFTN-PLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFL 489
L G AGG+ + T P + +K+++Q ++ G L +G+ G YKG +
Sbjct: 13 LTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALM 72
Query: 490 RDIPFSAIYFPVYAHC-----KLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKT 544
+ +++ F Y C K+ D+ + L AAG+ A AA + P +++K
Sbjct: 73 AYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKC 132
Query: 545 RLQV---------AARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTL 595
RLQ A++ T +S V + IL+++GP F+ G ++ + + P +
Sbjct: 133 RLQTMYEMEMSGKIAKSHNTIWSVV----KGILKKDGPLGFYHGLSSTLLQEVPGYFFFF 188
Query: 596 VTYELLQRWF 605
YEL + +F
Sbjct: 189 GGYELSRSFF 198
Score = 33.1 bits (74), Expect = 0.86
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 6/82 (7%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G VAG V+P+D +K+R+Q G G + V+R EG LY GL
Sbjct: 216 GGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFI------GTLLSVVRNEGIVALYSGL 269
Query: 393 IPQLIGVAPEKAIKLTVNDFVR 414
+I P ++ R
Sbjct: 270 KATMIRAIPANGALFVAYEYSR 291
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 96.7 bits (239), Expect = 6e-20
Identities = 77/298 (25%), Positives = 129/298 (43%), Gaps = 35/298 (11%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGS------------GSVVGELMYKNSFDCFKKVL 380
G G VGA P+++VKTR+Q+ + G+ V ++ C K +L
Sbjct: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72
Query: 381 RYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQ 440
EG L+RGL P L+GVAP +AI ++K +++ AG +
Sbjct: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132
Query: 441 VIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSA 496
+ TNP+ ++K RLQ+ R+ A +R + G+ G Y+G A + I +
Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191
Query: 497 IYFPVYAHCKLLLAD-------ENGHVG------GLNLLAAGAMAGVPAASLVTPADVIK 543
I+F +Y K L + EN + ++ A A + A ++ P V++
Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250
Query: 544 TRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELL 601
TRL R T Y +++EEG + ++G + R P + + TYEL+
Sbjct: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304
Score = 75.5 bits (184), Expect = 2e-13
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Query: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 469
+ AGGC G I T PLE+VK RLQ +AG ++ GP
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 470 NVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAG 529
+L G L++G + P AIYF Y++CK L D + + AMAG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 530 VPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSP 589
A + P +IKTRLQ+ AR G +C RK+ + +G F++G +A +
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS-YAGIS 188
Query: 590 QFGVTLVTYELLQR 603
+ + V YE +++
Sbjct: 189 ETVIHFVIYESIKQ 202
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 95.9 bits (237), Expect = 1e-19
Identities = 65/203 (32%), Positives = 107/203 (52%), Gaps = 18/203 (8%)
Query: 315 LGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFD 374
LG+ L + E RF GS+AGA T +YP++++KTR+ +R YK D
Sbjct: 271 LGQQETLHVQE---RFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLD 320
Query: 375 CFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR---DGSVPLPAEVL 431
C +++L EG YRG +P ++G+ P I L V + +++ + ++ D + P +L
Sbjct: 321 CARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLL 380
Query: 432 AGGCAGGS-QVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKA 486
A G + I + PL +V+ R+Q I GP++S L +LR + G+ GLY+G
Sbjct: 381 ACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAP 440
Query: 487 CFLRDIPFSAIYFPVYAHCKLLL 509
F++ IP +I + VY + K L
Sbjct: 441 NFMKVIPAVSISYVVYENMKQAL 463
Score = 94.7 bits (234), Expect = 2e-19
Identities = 62/181 (34%), Positives = 94/181 (51%), Gaps = 9/181 (4%)
Query: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGA 484
+++AG AG T PL+ +K+ +QV T R++ L LR + GI L++G
Sbjct: 188 QLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTN--RLNILGGLRSMVLEGGIRSLWRGN 245
Query: 485 KACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKT 544
L+ P SAI F Y K + + + AG++AG A +++ P +V+KT
Sbjct: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
Query: 545 RLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
RL + R GQ Y G++DC R+IL EGP AF++G V P G+ L YE L+ W
Sbjct: 306 RLTLR-RTGQ--YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNW 362
Query: 605 F 605
+
Sbjct: 363 W 363
Score = 79.3 bits (194), Expect = 1e-14
Identities = 69/279 (24%), Positives = 117/279 (41%), Gaps = 17/279 (6%)
Query: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
G+VAGAV T P+D +K MQ + + N + ++ G L+RG
Sbjct: 192 GAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL------NILGGLRSMVLEGGIRSLWRGN 245
Query: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
++ +APE AIK + ++ + ++ + +AG AG + P+E++K
Sbjct: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
Query: 453 RLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL 508
RL + TG L+ R + G Y+G L IP++ I VY K
Sbjct: 306 RLTLR---RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNW 362
Query: 509 LADENGH----VGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCF 564
+ H G L LLA G ++ P +++TR+Q A ++
Sbjct: 363 WLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLL 422
Query: 565 RKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
R IL +EG ++G A + P ++ V YE +++
Sbjct: 423 RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,137,406
Number of Sequences: 37866
Number of extensions: 1058378
Number of successful extensions: 3356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2535
Number of HSP's gapped (non-prelim): 317
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.