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Search of human proteins with 199559779
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|199559779 coiled-coil domain containing 8 [Homo sapiens] 1075 0.0
gi|52486265 paraneoplastic antigen MA1 [Homo sapiens] 73 6e-13
gi|156766054 PNMA-like 1 isoform b [Homo sapiens] 69 1e-11
gi|39780597 PNMA-like 1 isoform a [Homo sapiens] 69 1e-11
gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo sa... 67 3e-11
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 59 9e-09
gi|11464969 paraneoplastic antigen MA2 [Homo sapiens] 58 2e-08
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 56 7e-08
gi|60097902 filaggrin [Homo sapiens] 54 4e-07
gi|156766066 paraneoplastic antigen like 5 [Homo sapiens] 54 4e-07
gi|156766064 paraneoplastic antigen like 5 [Homo sapiens] 54 4e-07
gi|24308384 paraneoplastic antigen like 5 [Homo sapiens] 54 4e-07
gi|30795231 brain abundant, membrane attached signal protein 1 [... 52 1e-06
gi|153070260 myristoylated alanine-rich protein kinase C substra... 51 3e-06
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 50 7e-06
gi|24415404 MDN1, midasin homolog [Homo sapiens] 49 1e-05
gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 49 1e-05
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 48 2e-05
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 47 3e-05
gi|19923584 modulator of apoptosis 1 [Homo sapiens] 47 3e-05
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi... 47 3e-05
gi|239508698 PREDICTED: similar to mucin [Homo sapiens] 47 4e-05
gi|4502805 chromogranin A precursor [Homo sapiens] 47 6e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 47 6e-05
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 45 1e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 45 1e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 45 1e-04
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 45 2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 2e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 45 2e-04
>gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
Length = 538
Score = 1075 bits (2781), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME
Sbjct: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
Query: 61 KSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQG 120
KSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQG
Sbjct: 61 KSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQG 120
Query: 121 PRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQEKQPSAPPARRRVNLPVPMF 180
PRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQEKQPSAPPARRRVNLPVPMF
Sbjct: 121 PRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQEKQPSAPPARRRVNLPVPMF 180
Query: 181 EDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAP 240
EDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAP
Sbjct: 181 EDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAP 240
Query: 241 EGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAA 300
EGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAA
Sbjct: 241 EGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAA 300
Query: 301 DSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQR 360
DSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQR
Sbjct: 301 DSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQR 360
Query: 361 EEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAP 420
EEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAP
Sbjct: 361 EEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAP 420
Query: 421 AVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVRF 480
AVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVRF
Sbjct: 421 AVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVRF 480
Query: 481 QTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEARAEAEQGEQEDQL 538
QTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEARAEAEQGEQEDQL
Sbjct: 481 QTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEARAEAEQGEQEDQL 538
>gi|52486265 paraneoplastic antigen MA1 [Homo sapiens]
Length = 353
Score = 73.2 bits (178), Expect = 6e-13
Identities = 36/75 (48%), Positives = 48/75 (64%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
+L++ VDY IPRE+ GGVW+V+ KP T +AEF ERL FL EG T++DVAR++
Sbjct: 65 LLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLG 124
Query: 61 KSTPHPPQPPKKPKE 75
P P P+ P E
Sbjct: 125 FQNPTPTPGPEMPAE 139
>gi|156766054 PNMA-like 1 isoform b [Homo sapiens]
Length = 378
Score = 68.6 bits (166), Expect = 1e-11
Identities = 32/75 (42%), Positives = 49/75 (65%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
++++GE V+ IPRE GGVWRV+ + T++AEF + L +FL+ EGRT EDV R+++
Sbjct: 70 LIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDVVRLLQ 129
Query: 61 KSTPHPPQPPKKPKE 75
+ P Q +P E
Sbjct: 130 LNHPTLSQNQHQPPE 144
>gi|39780597 PNMA-like 1 isoform a [Homo sapiens]
Length = 439
Score = 68.6 bits (166), Expect = 1e-11
Identities = 32/75 (42%), Positives = 49/75 (65%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
++++GE V+ IPRE GGVWRV+ + T++AEF + L +FL+ EGRT EDV R+++
Sbjct: 70 LIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDVVRLLQ 129
Query: 61 KSTPHPPQPPKKPKE 75
+ P Q +P E
Sbjct: 130 LNHPTLSQNQHQPPE 144
>gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo
sapiens]
Length = 463
Score = 67.4 bits (163), Expect = 3e-11
Identities = 29/63 (46%), Positives = 42/63 (66%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
+L++ +D+DY L+PRE+ GG W VI KP + EF RL +FLEEE RT+ D+ R++
Sbjct: 66 LLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDMNRVLG 125
Query: 61 KST 63
T
Sbjct: 126 SDT 128
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 59.3 bits (142), Expect = 9e-09
Identities = 68/284 (23%), Positives = 109/284 (38%), Gaps = 25/284 (8%)
Query: 198 VSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCV 257
+ Q+ K G A PG ST G S G + D
Sbjct: 1689 LQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEG 1748
Query: 258 PQASPRRWRPKINWA-----SFRRRRKEQTAPTGQGADI-EADQGGEAADSQREEAIAD- 310
Q R PK+ A + R K + T G+++ EA+Q GE + E
Sbjct: 1749 SQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGS 1808
Query: 311 ------QREGAAGNQRAGAPAD--QGAEAADNQREEAADNQRAGAPAEEGAEAADNQREE 362
Q E AAG + +D +G EA + + E +++ AP EG +A + + E
Sbjct: 1809 GHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEG-DAQEAEGEA 1867
Query: 363 AADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQRE--------EAVHD 414
+++ EAP + ++ E + + P +G+E + ++E EA+
Sbjct: 1868 QPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALET 1927
Query: 415 QRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSA 458
+ E P +GA+ Q A+ A Q AE + QEAE A
Sbjct: 1928 EGEDEPESEGAEAQEAE-EAAQEAEGQTQPESEVIESQEAEEEA 1970
Score = 57.0 bits (136), Expect = 4e-08
Identities = 71/327 (21%), Positives = 125/327 (38%), Gaps = 32/327 (9%)
Query: 145 ESEDDEELVEAFLRRQEKQPSAPPARRRVNLPVPMFEDNLGPQLSKADRWREYVSQVSWG 204
ESED E L E + QE + A P V P E + ++ + S G
Sbjct: 1973 ESEDVEAL-EVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031
Query: 205 KLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRR 264
+ + V+G + G+A+ S VE APE +A P
Sbjct: 2032 EEAQEVEGETQKTE---GDAQPESDGVE------APEAEEEAQEAEGEVQEAEGEAHPES 2082
Query: 265 WRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAI-ADQREGAAGNQRAG- 322
A + + P +G + +G ++Q+ E I A + EG A + G
Sbjct: 2083 EDVDAQEA------EGEAQPESEGVEAPEAEG----EAQKAEGIEAPETEGEAQPESEGI 2132
Query: 323 -APADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTD 381
AP +G +++ EA D + P EG EA + + E + + EAP +
Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP--------E 2184
Query: 382 NHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEA- 440
E +++ EAP +G + + EA + E P +G + A+ A +E
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGE 2244
Query: 441 AHNQRAGAPGIQEAEVSAAQGTTGTAP 467
++ G+P + + + + + ++P
Sbjct: 2245 TQGEKKGSPQVSLGDGQSEEASESSSP 2271
Score = 45.8 bits (107), Expect = 1e-04
Identities = 57/256 (22%), Positives = 96/256 (37%), Gaps = 30/256 (11%)
Query: 222 GEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRW-------RPKINWASF 274
GEA+ S VE+ + + G+ + DV P+A P+ W
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQ-EAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEW--- 1897
Query: 275 RRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADN 334
+ P +GA EA + + A + E A + EG + GA A + EAA
Sbjct: 1898 ------EVQPESEGA--EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAA-- 1947
Query: 335 QREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPAD-QRSQGTDNHREEAADNQRA 393
+EA + + E EA + + E+ D + E + Q ++G E +++
Sbjct: 1948 --QEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG-----EAQPESEDV 2000
Query: 394 EAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQ- 452
EAP +G + + D E P +G + Q + + A + G +
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEA 2060
Query: 453 EAEVSAAQGTTGTAPG 468
E E A+G A G
Sbjct: 2061 EEEAQEAEGEVQEAEG 2076
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 18/202 (8%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQRE--EAADNQR 344
+ D+EA + A + E+ + E + GA A + + A + E EA + +
Sbjct: 1870 ESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG 1929
Query: 345 AGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVT 404
P EGAEA + EEAA Q ++G E ++Q AE A SE
Sbjct: 1930 EDEPESEGAEA--QEAEEAA----------QEAEGQTQPESEVIESQEAEEEAQPESEDV 1977
Query: 405 DNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQ---EAEVSAAQG 461
+ E V Q A +++ A G+ EA + + G++ ++E AQ
Sbjct: 1978 E-ALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQE 2036
Query: 462 TTGTAPGARARKQVKTVRFQTP 483
G Q ++ + P
Sbjct: 2037 VEGETQKTEGDAQPESDGVEAP 2058
Score = 32.3 bits (72), Expect = 1.1
Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 308 IADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQ 367
+AD+ GAAG G D G D+ E + +AG + EG D + E A
Sbjct: 975 LADETTGAAGGGLRGPEVDPG---DDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGA---- 1027
Query: 368 RAEAPADQRSQGTDNHREEAADNQRAEAPADQGSE 402
+D Q + + AA +EAPA+ G++
Sbjct: 1028 -LLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAGAD 1061
>gi|11464969 paraneoplastic antigen MA2 [Homo sapiens]
Length = 364
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/97 (36%), Positives = 49/97 (50%)
Query: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
+L++ ED D IP EV+ GGVW+VI K ++ EF ERL FLE+EG+T+ + R +
Sbjct: 66 LLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALG 125
Query: 61 KSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTY 97
+ P P E Q M P L+ Y
Sbjct: 126 QEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRY 162
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 56.2 bits (134), Expect = 7e-08
Identities = 68/294 (23%), Positives = 108/294 (36%), Gaps = 37/294 (12%)
Query: 200 QVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQ 259
Q + G +RR G +P A + + A E A + A + DR A VP
Sbjct: 42 QPAGGTGQRRGSGSSPSA-----DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPT 96
Query: 260 ASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQ 319
+S R R+R + Q P G + +AD QR + D+ E AA
Sbjct: 97 SSGHRTEK-------RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQ---DREEEAAA-- 144
Query: 320 RAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQG 379
A P +G +R++ G G+ ++ + ++ A ++ EA A
Sbjct: 145 -APVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTS 203
Query: 380 TDNHREEAADNQRAEAPA--------DQGSEVTDNQREEAVHDQRERAPA-------VQG 424
+ E+ Q PA + S D QR + ++ APA +
Sbjct: 204 RGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEK 263
Query: 425 ADNQRAQAR----AGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQ 474
Q+ Q R GQR + ++ A G Q+ E AA T+ G R K+
Sbjct: 264 RKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKR 317
Score = 45.1 bits (105), Expect = 2e-04
Identities = 49/209 (23%), Positives = 79/209 (37%), Gaps = 40/209 (19%)
Query: 292 EADQGGEAADSQREEAIADQRE------GAAGNQRAGAPADQGAEAADNQREEAADNQRA 345
E+ +G + ++++ + + Q++ G G +R + +AD Q + + + A
Sbjct: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSG----SSPSADQQGAQDREEEAA 72
Query: 346 GAPAEEGAEAADNQREEAA------DNQRAE---------APADQRSQGTDNHREEAADN 390
APA + A D + E AA R E PA Q + +AD
Sbjct: 73 AAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQ 132
Query: 391 QRA-----EAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQR 445
QRA EA A ++ E+ Q +R PA GQR + +
Sbjct: 133 QRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPA----------GGTGQRRGSGSSPS 182
Query: 446 AGAPGIQEAEVSAAQGTTGTAPGARARKQ 474
A G Q+ E AA T+ G R K+
Sbjct: 183 ADQQGAQDREEEAAAAPAPTSRGHRTEKR 211
Score = 30.8 bits (68), Expect = 3.3
Identities = 44/189 (23%), Positives = 67/189 (35%), Gaps = 28/189 (14%)
Query: 216 RAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFR 275
R+ P + R E+A +AP TS G R PQ RR R
Sbjct: 231 RSSPSADQQRAQDREEEAA---AAPAPTSRGHRTEKRK----PQQPQRR---PAGGTGQR 280
Query: 276 RRRKEQTAPTGQGADIEADQG---------GEAADSQREEAIADQREGAAGNQR-AGAPA 325
R + QGA ++ G + ++ + Q G G +R +G +
Sbjct: 281 RGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS 340
Query: 326 DQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHRE 385
+ A ++ EEAA A P G ++ E+ Q PA Q +
Sbjct: 341 SANQQGAQDREEEAA---AAPVPTSSG-----HRTEKRKPQQPQRRPAAGTGQRRGSGSS 392
Query: 386 EAADNQRAE 394
+AD QRA+
Sbjct: 393 PSADQQRAQ 401
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 53.9 bits (128), Expect = 4e-07
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 28/217 (12%)
Query: 284 PTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQ 343
P G ++D G + DS+R R G+A G+ +Q + + + R D
Sbjct: 2238 PRGSSVSQDSDSEGHSEDSER-------RSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA 2290
Query: 344 RAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTD---NHREEAADNQR-------- 392
G AE ++ + E ++ Q A + RS + +H +++AD+ R
Sbjct: 2291 GHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ 2350
Query: 393 -AEAPAD------QGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQR 445
+ A D GS+ +D++ D + + Q +Q++ + + A + R
Sbjct: 2351 ASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGR 2410
Query: 446 AGAPGIQ---EAEVSAAQGTTGTAPGARARKQVKTVR 479
+G+ Q + +A G TGT+ G R K R
Sbjct: 2411 SGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQAR 2447
Score = 46.6 bits (109), Expect = 6e-05
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 19/194 (9%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
RR + Q + Q +D E G + DS+R G+A G+ +Q + + +
Sbjct: 2882 RRSRRQGSSVSQDSDSE----GHSEDSERWS-------GSASRNHHGSAQEQLRDGSRHP 2930
Query: 336 REEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEA 395
R D G A+ ++ + ++ Q A + RS + H + + A
Sbjct: 2931 RSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH----GSHHQQSA 2986
Query: 396 PADQGSEVTDNQREEAVHDQRERA-PAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEA 454
+ + S + Q AV D R Q +DN+ + ++ +AH Q A Q++
Sbjct: 2987 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQ---AGSHQQS 3043
Query: 455 EVSAAQGTTGTAPG 468
+A+G +G G
Sbjct: 3044 HQESARGRSGETSG 3057
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/243 (20%), Positives = 87/243 (35%), Gaps = 47/243 (19%)
Query: 227 ASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTG 286
AS+ +S+G S +G S G R NW G
Sbjct: 2537 ASSRADSSGHSQVGQGQSEGPRTSR------------------NW--------------G 2564
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
++D G + DS+R G+A G+ +Q + + + R D G
Sbjct: 2565 SSFSQDSDSQGHSEDSERWS-------GSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2617
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDN 406
A+ ++ + ++ Q A + RS + H + + A + + S +
Sbjct: 2618 HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH----GSHHQQSADSSRHSGIGHG 2673
Query: 407 QREEAVHDQRERA-PAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGT 465
Q AV D R Q +DN+ + ++ +AH Q A Q++ +A+G +G
Sbjct: 2674 QASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQ---AGSHQQSHQESARGRSGE 2730
Query: 466 APG 468
G
Sbjct: 2731 TSG 2733
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/213 (22%), Positives = 89/213 (41%), Gaps = 28/213 (13%)
Query: 276 RRRKEQTAPTGQGAD---------IEADQGGEAADSQRE-EAIADQREGAAGNQRAGAPA 325
R +E A G A+ E GG+AA SQ + + +R G+ Q A +
Sbjct: 1634 RSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSST 1693
Query: 326 DQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHRE 385
D G +R++++ +G G++A+D++ + ++ + Q +H +
Sbjct: 1694 DSGT----GRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH-Q 1748
Query: 386 EAADNQRAEAPADQGS---EVTDNQREEAVHDQ-------RERAPAVQGADNQRAQA-RA 434
E+ Q E GS +V+ +++ E+ H + R+R+ Q D+ R A +
Sbjct: 1749 ESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQE 1808
Query: 435 GQRAEAAH--NQRAGAPGIQEAEVSAAQGTTGT 465
GQ H + R G G + + G +G+
Sbjct: 1809 GQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGS 1841
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/216 (21%), Positives = 85/216 (39%), Gaps = 32/216 (14%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
R RK + + Q D E G + DS+R G+A G+ +Q + + +
Sbjct: 288 RTRKRRGSRVSQDRDSE----GHSEDSERHS-------GSASRNHHGSAWEQSRDGSRHP 336
Query: 336 REEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNH---REEAADNQR 392
R D G A+ ++ E ++ Q A + RS + H +++AD+ R
Sbjct: 337 RSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR 396
Query: 393 ---------AEAPADQGSEVTDNQR--EEAVHDQRERAPAVQGADNQRAQARAGQRAEAA 441
+ A +D+G + + + H + +V G + ++ Q +
Sbjct: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRG 456
Query: 442 HN-QRAGAPGIQEAEVS------AAQGTTGTAPGAR 470
+ +R+G G +VS +A G TGT+ G R
Sbjct: 457 RSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGR 492
Score = 42.7 bits (99), Expect = 8e-04
Identities = 35/182 (19%), Positives = 70/182 (38%), Gaps = 10/182 (5%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
QG+ + D +DSQ +++ G+A G+ +Q + + + D G
Sbjct: 1914 QGSSVSQD-----SDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHG 1968
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDN 406
A+ ++ E ++ Q A + RS + H + +Q A + + S +
Sbjct: 1969 HSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH---GSHHQLQSADSSRHSGIGHG 2025
Query: 407 QREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTA 466
Q AV D R + A + + + +AG Q++ +A+G +G +
Sbjct: 2026 QASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPH--QQSHKESARGQSGES 2083
Query: 467 PG 468
G
Sbjct: 2084 SG 2085
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/159 (20%), Positives = 64/159 (40%), Gaps = 10/159 (6%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
QG+ + D +DSQ +++ G+A G+ +Q + + + D G
Sbjct: 3535 QGSSVSQD-----SDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG 3589
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDN 406
AE ++ + E ++ Q A + RS + H + + A + + S +
Sbjct: 3590 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERH----GSHHQQSADSSRHSGIGHG 3645
Query: 407 QREEAVHDQRER-APAVQGADNQRAQARAGQRAEAAHNQ 444
Q AV D R + Q +D++ + ++ +AH Q
Sbjct: 3646 QASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQ 3684
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/182 (18%), Positives = 69/182 (37%), Gaps = 11/182 (6%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
QG+ + D +DS+R +++ G+A G+ +Q + + + D G
Sbjct: 1266 QGSSVSQD-----SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDN 406
A+ ++ + E ++ Q + RS + H + A + + S +
Sbjct: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERH----GSRHQQSADSSRHSGIGHR 1376
Query: 407 QREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTA 466
Q AV D R + N + + + +AG Q++ +A+G +G +
Sbjct: 1377 QASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPH--QQSHKESARGQSGES 1434
Query: 467 PG 468
G
Sbjct: 1435 SG 1436
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/206 (17%), Positives = 79/206 (38%), Gaps = 27/206 (13%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
QG+ + D +DSQ +++ G+A G+ +Q + + + R D G
Sbjct: 617 QGSSVSQD-----SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 671
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTD----NHREEAADNQRAEAP------ 396
A+ ++ + ++ Q A + RS + H+ ++AD+ R
Sbjct: 672 HSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQAS 731
Query: 397 ---------ADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAG 447
GS+ TD++ D + + Q +Q++ + + ++R+G
Sbjct: 732 SAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSG 791
Query: 448 APGIQ---EAEVSAAQGTTGTAPGAR 470
+ Q + ++ G TG + G R
Sbjct: 792 SFLYQVSTHKQSESSHGWTGPSTGVR 817
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/190 (21%), Positives = 71/190 (37%), Gaps = 18/190 (9%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
RR + Q + Q +D E G + DS+R G+A G+ +Q + +
Sbjct: 3206 RRSRRQGSSVSQDSDSE----GHSEDSERWS-------GSASRNHRGSVQEQSRHGSRHP 3254
Query: 336 REEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEA 395
R D G A+ ++ E ++ Q A + RS + H + A
Sbjct: 3255 RSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERH----GSRHQQSA 3310
Query: 396 PADQGSEVTDNQREEAVHDQRE-RAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEA 454
+ + S + Q AV D R + Q +D++ + ++ + H Q P Q
Sbjct: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ--AGPHQQSH 3368
Query: 455 EVSAAQGTTG 464
+ SA + G
Sbjct: 3369 QESARDRSGG 3378
Score = 39.7 bits (91), Expect = 0.007
Identities = 42/219 (19%), Positives = 84/219 (38%), Gaps = 24/219 (10%)
Query: 277 RRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQR 336
RR Q + Q D G + + + +D G +G++ A + N+
Sbjct: 849 RRGRQGSHHEQSVDRSGHSGSHHSHTT-SQGRSDASRGQSGSRSA-------SRTTRNEE 900
Query: 337 EEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAP 396
+ ++ +G+ E + AD R A ++E R QG+ ++ ++ ++
Sbjct: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960
Query: 397 ADQGSEVTDNQ---REEAVHDQR-------ERAPAVQGADNQR------AQARAGQRAEA 440
GS +++ +E++ H R +RA AD+ R A+ +G +A +
Sbjct: 961 RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS 1020
Query: 441 AHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVR 479
+H Q +PG + + G R+ VR
Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVR 1059
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/205 (19%), Positives = 80/205 (39%), Gaps = 26/205 (12%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
QG+ + D +DS+ +++ G+A G+ +Q + + R D G
Sbjct: 942 QGSSVSQD-----SDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHG 996
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNH---REEAADNQR---------AE 394
A+ ++ E ++ Q A + RS + H +++AD+ R +
Sbjct: 997 HSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASS 1056
Query: 395 APAD------QGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGA 448
A D GS+ +D++ D + + Q +Q++ + + + R+G+
Sbjct: 1057 AVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGS 1116
Query: 449 PGIQ---EAEVSAAQGTTGTAPGAR 470
Q + +A G T T+ G R
Sbjct: 1117 FIYQVSTHEQSESAHGRTRTSTGRR 1141
Score = 35.0 bits (79), Expect = 0.17
Identities = 48/226 (21%), Positives = 84/226 (37%), Gaps = 26/226 (11%)
Query: 281 QTAPTGQGADIEADQGGEAADSQREEAIADQRE---GAAGNQRAGAPADQGAEAADNQRE 337
QTAP+ G + + +A +S R A D ++ G G+ R G ++ D
Sbjct: 1457 QTAPSTGGR--QGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGH 1514
Query: 338 EAADNQRA-------GAPAEEGAEAADNQ---REEAADNQRAEAPADQRSQ---GTDNHR 384
+ + + G +A Q E++ D R G+ H
Sbjct: 1515 SGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHS 1574
Query: 385 EEA-ADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQ---RAQARAGQRAEA 440
+ ++ ++ QGS V+ ++ E + ER ++ R Q+R G R
Sbjct: 1575 QVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPR 1634
Query: 441 AHNQRAGAPGIQEAEVSAAQGT--TGTAPGARARKQVKTVRFQTPG 484
+H + + G AE S GT T+ G +A + R +PG
Sbjct: 1635 SHQEDRASHG-HSAESSRQSGTRHAETSSGGQAASSQEQAR-SSPG 1678
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/223 (18%), Positives = 78/223 (34%), Gaps = 44/223 (19%)
Query: 277 RRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQR 336
RR Q + Q D G + + + +D G +G++ A ++ D R
Sbjct: 3442 RRGRQGSHYEQSVDRSGHSGSHHSHTT-SQGRSDASRGQSGSRSASRQTRNDEQSGDGSR 3500
Query: 337 EEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTD--------------- 381
+ + E + AD+ R + ++ P R+QG+
Sbjct: 3501 HSWSHHH-------EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
Query: 382 --------NHREEAADNQR---------AEAPADQGSEVTDNQREEAVHDQRERAPAVQG 424
NHR A + R E A G ++ R+ H +
Sbjct: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHS-AESSRQSGTHHAENSSGGQAA 3612
Query: 425 ADNQRAQARAGQRAEAAHNQRAGA---PGIQEAEVSAAQGTTG 464
+ +++A++ AG+R + H Q A + GI + S+A +G
Sbjct: 3613 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3655
Score = 33.9 bits (76), Expect = 0.39
Identities = 36/169 (21%), Positives = 71/169 (42%), Gaps = 14/169 (8%)
Query: 297 GEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAA 356
G S E+++ R G +G+ + + ++A+ Q + ++ A ++
Sbjct: 3767 GGRQGSYHEQSV--DRSGHSGSHHSHTTSQGRSDASHGQ----SGSRSASRETRNEEQSG 3820
Query: 357 DNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQR 416
D R + + A AD S+ + + + E+A ++R+ QGS V+ + EA +
Sbjct: 3821 DGSRHSGSRHHEASTQADS-SRHSQSGQGESAGSRRSRR---QGSSVSQDSDSEAYPEDS 3876
Query: 417 ERAPAVQGADNQ---RAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGT 462
ER ++ R Q+R G R + R A +Q + V + T
Sbjct: 3877 ERRSESASRNHHGSSREQSRDGSR-HPGSSHRDTASHVQSSPVQSDSST 3924
Score = 33.1 bits (74), Expect = 0.66
Identities = 38/188 (20%), Positives = 66/188 (35%), Gaps = 21/188 (11%)
Query: 298 EAADSQREEAIADQRE---GAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAE 354
+A DS R A + ++ G++R G ++ D + + + A
Sbjct: 1148 QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1207
Query: 355 AADNQREEAADNQRAEAPADQRSQGTDNHREEA---ADNQR-----------AEAPADQG 400
+ A+ R + + S+ + + EA AD+ R + QG
Sbjct: 1208 HGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQG 1267
Query: 401 SEVTDNQREEAVHDQRERAPAVQGAD---NQRAQARAGQRAEAAHNQRAGAPGIQEAEVS 457
S V+ + E D ER + + R Q+R G R H + + G A+ S
Sbjct: 1268 SSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG-HSADSS 1326
Query: 458 AAQGTTGT 465
GT T
Sbjct: 1327 RQSGTHHT 1334
Score = 33.1 bits (74), Expect = 0.66
Identities = 32/159 (20%), Positives = 61/159 (38%), Gaps = 25/159 (15%)
Query: 309 ADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQR 368
+D G +G++ A ++ D R +G+ E + AD+ +
Sbjct: 2501 SDASHGHSGSRSASRQTRNDEQSGDGSRH-------SGSRHHEASSRADSSGHSQVGQGQ 2553
Query: 369 AEAPADQRSQGT-----DNHREEAADNQRAEAPADQG------SEVTDNQREEAVHDQRE 417
+E P R+ G+ + + + D++R A + ++ D R H Q +
Sbjct: 2554 SEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSH-QED 2612
Query: 418 RAPAVQGADNQR------AQARAGQRAEAAHNQRAGAPG 450
RA AD+ R Q +G +A ++H Q + G
Sbjct: 2613 RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2651
Score = 32.7 bits (73), Expect = 0.86
Identities = 35/167 (20%), Positives = 63/167 (37%), Gaps = 27/167 (16%)
Query: 322 GAPADQGAEAADNQREEAADNQR-AGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGT 380
G + A E++ D R +G+ E + AD+ R ++ P R+QG+
Sbjct: 560 GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGS 619
Query: 381 -----DNHREEAADNQRAEAPADQG------SEVTDNQREEAVHDQRERAPAVQGADNQR 429
+ + + D++R A + + D R H + +RA AD+ R
Sbjct: 620 SVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHE-DRAGHGHSADSSR 678
Query: 430 ------AQARAGQRAEAAHNQRAGAPG--------IQEAEVSAAQGT 462
Q + +A ++H Q + G +Q A+ S GT
Sbjct: 679 KSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGT 725
Score = 32.7 bits (73), Expect = 0.86
Identities = 34/185 (18%), Positives = 73/185 (39%), Gaps = 23/185 (12%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAG 346
Q D G + + +E +D G +G++ + N+++ ++ +G
Sbjct: 1831 QSVDSSGHSGSHHSHTTSQER-SDVSRGQSGSRSV-------SRQTRNEKQSGDGSRHSG 1882
Query: 347 APAEEGAEAADNQREEAADNQRAEAPADQRSQGT-----DNHREEAADNQRAEAPADQG- 400
+ E + AD+ R ++ P R+QG+ + + + D++R A +
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 1942
Query: 401 -----SEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAE 455
+ D R H + +RA AD+ R ++G R + ++ A ++A
Sbjct: 1943 LGSAWEQSRDGSRHPGSHHE-DRAGHGHSADSSR---QSGTRHTESSSRGQAASSHEQAR 1998
Query: 456 VSAAQ 460
SA +
Sbjct: 1999 SSAGE 2003
Score = 32.0 bits (71), Expect = 1.5
Identities = 40/202 (19%), Positives = 71/202 (35%), Gaps = 23/202 (11%)
Query: 281 QTAPTGQGADIEADQGGEAADSQREEAIADQRE---GAAGNQRAGAPADQGAEAADNQRE 337
Q+AP+ G + +A DS R A + ++ G G R G ++ D
Sbjct: 2106 QSAPSTGGR--QGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGH 2163
Query: 338 EAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEA---ADNQR-- 392
+ + + A + A+ + + S+ + +H EA AD+ R
Sbjct: 2164 SGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHS 2223
Query: 393 ---------AEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQ---RAQARAGQRAEA 440
+GS V+ + E + ER ++ + Q+R G R
Sbjct: 2224 LVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPR 2283
Query: 441 AHNQRAGAPGIQEAEVSAAQGT 462
+H++ G AE S GT
Sbjct: 2284 SHHEDRAGHG-HSAESSRQSGT 2304
Score = 30.0 bits (66), Expect = 5.6
Identities = 48/237 (20%), Positives = 86/237 (36%), Gaps = 51/237 (21%)
Query: 278 RKEQTAPTGQGADIEADQGGEAADS-----QREEAIADQREGAAGNQRAGAPADQG---- 328
R Q + +GQ A A + Q + A + + G Q + A D G
Sbjct: 683 RHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGS 742
Query: 329 --AEAADNQ-REEAADNQRAGAPAEEGAEAADNQ---REEAADNQRAEA----------- 371
++A D++ E +D Q + G +Q R+ + + R
Sbjct: 743 SGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQ 802
Query: 372 ---------PADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAV 422
P+ QG+ H E+A DN R A D D R +R R
Sbjct: 803 SESSHGWTGPSTGVRQGS--HHEQARDNSRHSASQDG----QDTIRGHPGSSRRGR---- 852
Query: 423 QGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVR 479
QG+ ++++ R+G +H+ + G + A++G +G+ +R + + R
Sbjct: 853 QGSHHEQSVDRSGH--SGSHHSHTTSQGRSD----ASRGQSGSRSASRTTRNEEQSR 903
>gi|156766066 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 15/104 (14%)
Query: 2 LQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVAR---- 57
+++ + V+Y +P + GG W V+ KP + EF RL FL++EGR++ DVAR
Sbjct: 67 IELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDVARALGC 126
Query: 58 -----------IMEKSTPHPPQPPKKPKEPRVRRRVQQMVTPPP 90
+M + P +PPK+ R + +P P
Sbjct: 127 CSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSP 170
>gi|156766064 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 15/104 (14%)
Query: 2 LQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVAR---- 57
+++ + V+Y +P + GG W V+ KP + EF RL FL++EGR++ DVAR
Sbjct: 67 IELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDVARALGC 126
Query: 58 -----------IMEKSTPHPPQPPKKPKEPRVRRRVQQMVTPPP 90
+M + P +PPK+ R + +P P
Sbjct: 127 CSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSP 170
>gi|24308384 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 15/104 (14%)
Query: 2 LQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVAR---- 57
+++ + V+Y +P + GG W V+ KP + EF RL FL++EGR++ DVAR
Sbjct: 67 IELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDVARALGC 126
Query: 58 -----------IMEKSTPHPPQPPKKPKEPRVRRRVQQMVTPPP 90
+M + P +PPK+ R + +P P
Sbjct: 127 CSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSP 170
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 52.0 bits (123), Expect = 1e-06
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 25/235 (10%)
Query: 204 GKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPR 263
GKL ++ KG+ V + + ++ G ++ EGT A + +A
Sbjct: 3 GKLSKKKKGY------NVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPA--EAKEG 54
Query: 264 RWRPKINW---ASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQR 320
+ +P + A + K+ A + E ++ AA+++ E A ++E AA
Sbjct: 55 KEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPA 114
Query: 321 AGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAA-DNQREEAADNQRAEAPADQRSQG 379
AG A + AEA A APAE A AA + +E + ++ EAPA +Q
Sbjct: 115 AGGEAPKAAEA-------------AAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQE 161
Query: 380 TDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARA 434
T + A+D++ + A S+ T E + + PA + + +A A
Sbjct: 162 TKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAPA 216
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 50.8 bits (120), Expect = 3e-06
Identities = 78/266 (29%), Positives = 109/266 (40%), Gaps = 66/266 (24%)
Query: 214 APRAG--------PGVGEARL--ASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQAS-- 261
AP AG P GEA + TA E S+A +SP A D P S
Sbjct: 95 APEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP-----KAEDGATPSPSNE 149
Query: 262 -PRRWRP--------KINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQR 312
P++ + K++ SF++ +KE G+G + EA AA+ ++EA
Sbjct: 150 TPKKKKKRFSFKKSFKLSGFSFKKNKKE----AGEGGEAEAP----AAEGGKDEA----- 196
Query: 313 EGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAP 372
AG A AEA E+AA A EEGA D Q EA + A AP
Sbjct: 197 --------AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQ--EAKPQEAAVAP 246
Query: 373 ADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRE-RAP--AVQGADNQR 429
+ A+D +A A++ S+V + + EEA AP A GA ++
Sbjct: 247 ----------EKPPASDETKA---AEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQ 293
Query: 430 AQARAGQRAEAAHNQRAGAPGIQEAE 455
A A + A AA + AP QEA+
Sbjct: 294 EAAPAEEPAAAAASSACAAPS-QEAQ 318
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 30/200 (15%)
Query: 291 IEADQGGEAADSQREEAI--------ADQREGAAGNQRAGAP--ADQGAEAADNQREEAA 340
+ D AA+S +E + AD+ E AA A +P A++G AA E A
Sbjct: 41 VNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGA 100
Query: 341 DNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQ- 399
APAE EAA+ AA+ + A A + S ++ + N+ + +
Sbjct: 101 SPVEKEAPAE--GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRF 158
Query: 400 ---------GSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAE--AAHNQRAGA 448
G N++E + E APA +G ++ A A AE AA ++A A
Sbjct: 159 SFKKSFKLSGFSFKKNKKEAGEGGEAE-APAAEGGKDEAAGGAAAAAAEAGAASGEQAAA 217
Query: 449 PGIQEAEVSAAQGTTGTAPG 468
PG + AA G G A G
Sbjct: 218 PGEE-----AAAGEEGAAGG 232
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 49.7 bits (117), Expect = 7e-06
Identities = 73/284 (25%), Positives = 99/284 (34%), Gaps = 58/284 (20%)
Query: 219 PGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPR-RWRPKINWASFRRR 277
P GE + VE A +G G+ D P+ RP++ S
Sbjct: 96 PQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGE 155
Query: 278 RK-------------EQTAPTGQGADIEA------DQGGEAADS-QREEAIAD--QREGA 315
E P G + E D G A DS E + D Q EG
Sbjct: 156 AGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP 215
Query: 316 AGNQ-----RAGAPADQGAEAADNQREEA--ADNQRAGAPAEEGAEAADNQREEAADNQR 368
AG+ R G D A D+ E D+ AG PA +G EA A D+
Sbjct: 216 AGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAG----VPAGDSVE 271
Query: 369 AEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQ 428
AE P A D+ AE PA + V+ ++ +A A++ A +
Sbjct: 272 AEGP--------------AGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
Query: 429 RAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPG-ARA 471
A G+ A A +EAEV +G+ APG ARA
Sbjct: 318 SAGRSPGELAWDA---------AEEAEVPGVKGSEEAAPGDARA 352
Score = 43.1 bits (100), Expect = 6e-04
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 20/183 (10%)
Query: 284 PTGQGADI--EADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAAD 341
P G+ + E Q G+ + S + EAI E AAG +P + +AA+
Sbjct: 285 PAGRARRVSGEPQQSGDGSLSPQAEAI----EVAAGESAGRSPGELAWDAAEEAEVPGVK 340
Query: 342 NQRAGAPAEEGAEAADN------QREEAADNQRAE-APADQRSQGTDNHREEAADN---- 390
AP + A+A ++ Q+E D +R E +P R + EE+ D+
Sbjct: 341 GSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHG 400
Query: 391 QRAEAPADQGSEVTDNQREEAVHDQRERAPAVQG--ADNQRAQARA-GQRAEAAHNQRAG 447
+ + A+ ++++++ EE + A V G D + ++ RA GQ + +AG
Sbjct: 401 EASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAG 460
Query: 448 APG 450
G
Sbjct: 461 YDG 463
Score = 42.7 bits (99), Expect = 8e-04
Identities = 66/258 (25%), Positives = 90/258 (34%), Gaps = 46/258 (17%)
Query: 230 AVESAGVSSAPEGTS---------PGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKE 280
A E GV+ P+G PG+ G+ P+ S
Sbjct: 4 AAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGS----------------EGA 47
Query: 281 QTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAA 340
+ AP G A EA GG + EA A GA G A A +GAE E +
Sbjct: 48 EEAPRGAAAVKEAGGGGP---DRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSG 104
Query: 341 DNQRAGAPAEEGAEA-----ADNQREEAADNQRAEAPADQRSQGTDNHRE-EAADNQRAE 394
Q GA GA+ A + E++A +R E A+QR + + EA D+ AE
Sbjct: 105 AQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQE-EAEQRPEVPEGSASGEAGDSVDAE 163
Query: 395 APADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEA----AHNQRAGAPG 450
P E E D E V D+ A+ AG +A N +A P
Sbjct: 164 GPLGDNIEA-----EGPAGDSVEAEGRV--GDSVDAEGPAGDSVDAEGPLGDNIQAEGPA 216
Query: 451 IQEAEVSAAQGTTGTAPG 468
+ G + A G
Sbjct: 217 GDSVDAEGRVGDSVDAEG 234
Score = 38.9 bits (89), Expect = 0.012
Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 12/159 (7%)
Query: 284 PTGQGADIEADQGGEAADSQREEAIADQREGAAGNQR--AGAPADQGAEAADNQRE--EA 339
P G G + G++ +++ + EG AG R +G P G + Q E E
Sbjct: 255 PAGDGVEAGVP-AGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEV 313
Query: 340 ADNQRAG-APAEEGAEAADNQREEAADNQRAEAPADQRSQ------GTDNHREEAADNQR 392
A + AG +P E +AA+ AP D R+ G +E D +R
Sbjct: 314 AAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEER 373
Query: 393 AEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQ 431
E + E EE D A +GA AQ
Sbjct: 374 RERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQ 412
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/286 (22%), Positives = 101/286 (35%), Gaps = 47/286 (16%)
Query: 279 KEQTAPTGQGADIEADQGGEAADS---QREEAIADQREGAA--GNQRA-------GAPAD 326
K Q + + EAD GG+ D Q +E D+ E GNQ P D
Sbjct: 4825 KSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDD 4884
Query: 327 QGAEAADNQREEAADNQR---------------AGAPAEEGAEAADNQREEAADNQRAEA 371
++ D E DN+ AG AEE E +Q E + + E
Sbjct: 4885 LNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEG 4944
Query: 372 PADQRSQGTDNHREEAADNQRAEAP------ADQGSEVTDNQREEAVHDQRERAPAVQGA 425
P++ + + AD+Q +A +++ + + + +EA + E PA QG
Sbjct: 4945 PSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGF 5004
Query: 426 DNQRAQAR--------AGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAP----GARARK 473
Q + R + E + G G++ + + A G AP G
Sbjct: 5005 QPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHG 5064
Query: 474 QVKTVRFQTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLR 519
Q G S F + + HT + KR P G+A N R
Sbjct: 5065 SGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP--GQADNER 5108
>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
Length = 555
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 8/161 (4%)
Query: 281 QTAPTGQGADIEADQGGEAADSQREE------AIADQREGAAGNQRAGAPADQGAEAADN 334
++ P + + A QGG AAD Q E A A EG R P + E A+
Sbjct: 44 ESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEV 103
Query: 335 QREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAE 394
EE A + P E AEA + E+AA+ + A D AA E
Sbjct: 104 GAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETE 163
Query: 395 APADQGSEVTDNQREEAVHDQR--ERAPAVQGADNQRAQAR 433
+ + + QR+ A +R E PA + +R R
Sbjct: 164 RVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGR 204
Score = 38.9 bits (89), Expect = 0.012
Identities = 45/175 (25%), Positives = 58/175 (33%), Gaps = 24/175 (13%)
Query: 294 DQGGEAADSQREEAIADQREGAAGNQRAGAP---------------ADQGAEAADNQRE- 337
D GGE D + A + + ++G + P A QG AAD Q E
Sbjct: 10 DPGGEGGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEA 69
Query: 338 ----EAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRA 393
AA+ P E G A E AE PA Q G EA
Sbjct: 70 PKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPA-QPEPGAGPEELEAEAGAEE 128
Query: 394 EAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGA 448
A +G EV E A A A+ +R + G+ + QR GA
Sbjct: 129 LEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVE---GEEEDKEETQRDGA 180
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 280 EQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQ-RAGAPADQGAEAADNQREE 338
E+ A G D +A+ GG REEA EG+ + AG ++ EA +Q E
Sbjct: 650 EEQACWEVGEDKQAEPGGRL--DIREEA-----EGSPETKVEAGKASEDRGEAGGSQ--E 700
Query: 339 AADNQRAGAPAEEGAEAADNQREEAADNQRA----EAPADQRSQGTDNHREEAADNQRAE 394
R G+ E A+ ++ ++ AD+ A E D+ + + E D QR E
Sbjct: 701 TKVRLREGSREETEAKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREE 760
Query: 395 APADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQR 445
A + G ++ +E+ V +++ Q A+ R GQR + H R
Sbjct: 761 AQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEAR 811
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 19/200 (9%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
R E + T A ++ GEA SQ E REG+ A +G + AD+
Sbjct: 672 REEAEGSPETKVEAGKASEDRGEAGGSQ--ETKVRLREGSREETEAKEEKSKGQKKADSM 729
Query: 336 R----EEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQ 391
EE ++ +E D QREEA + + + E Q
Sbjct: 730 EAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQ 789
Query: 392 RAEAPADQGSEVTDNQREEAVHDQRE--------RAP--AVQGADNQRAQARAGQRAEAA 441
AE + + QRE+ H+ R+ R+P A +G + ++ R EA
Sbjct: 790 EAEGVREDEDK---GQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERESGDGEAE 846
Query: 442 HNQRAGAPGIQEAEVSAAQG 461
+QRAG ++E +S G
Sbjct: 847 GDQRAGGYYLEEDTLSEGSG 866
>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
Length = 306
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/287 (23%), Positives = 105/287 (36%), Gaps = 42/287 (14%)
Query: 189 SKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDR 248
S+ D+W E + K P+ P + + A + G S+P G +
Sbjct: 19 SEGDQWLE----------NEKTKPLRPQQQP---QCQPAGGTGQRRGSGSSPSADQQGAQ 65
Query: 249 LGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAI 308
P + R R + R+ ++ Q P G + +AD Q +
Sbjct: 66 DREEEAAAAPAPTSRGHRTEK-----RKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQ-- 118
Query: 309 ADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGA---EAADNQREEAAD 365
D+ E AA A AP G + ++ AG G+ +AD QR + +
Sbjct: 119 -DREEEAAA---APAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDRE 174
Query: 366 NQRAEAPADQRSQGTDNHREEAADNQRAEA-PAD-----QGSEVTDNQREEAVHDQRERA 419
+ AP S HR E + + PA +GS + +++ QR +
Sbjct: 175 EEATAAPVPTSS----GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGS 230
Query: 420 PAVQGADNQRAQARAGQRAEAAHNQR--AGAPGIQEAEVSAAQGTTG 464
+ AD QRAQ R EAA QR AG G + +A TTG
Sbjct: 231 RSSPSADQQRAQDR---EEEAAQPQRRPAGGTGQRRGTAAAPVPTTG 274
Score = 40.0 bits (92), Expect = 0.005
Identities = 58/227 (25%), Positives = 84/227 (37%), Gaps = 32/227 (14%)
Query: 286 GQGADIEADQGGEAADSQREEAIADQREGAAGN--------QRAGAPADQGAEAADNQRE 337
G G+ ADQ G A + EEA A + G+ Q PA + ++
Sbjct: 52 GSGSSPSADQQG--AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSS 109
Query: 338 EAADNQRAGAPAEEGAEA-ADNQREEAADNQRAEAPADQRSQGTDNHR----EEAADNQR 392
+AD Q A EE A A A + ++ + P + + GT R +AD QR
Sbjct: 110 SSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQR 169
Query: 393 A-----EAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARA----------GQR 437
A EA A + ++ E+ Q + PA G QR +R+ GQR
Sbjct: 170 AQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPA--GGTGQRRGSRSSPSRQPAGGTGQR 227
Query: 438 AEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVRFQTPG 484
+ + A Q+ E AAQ A G R+ T G
Sbjct: 228 RGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTG 274
>gi|19923584 modulator of apoptosis 1 [Homo sapiens]
Length = 351
Score = 47.4 bits (111), Expect = 3e-05
Identities = 20/53 (37%), Positives = 33/53 (62%)
Query: 7 DVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIM 59
+ + L+P+E+ GG+WRVI KP + F RL +FL EG T+ +++R +
Sbjct: 72 ETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGELSRAL 124
>gi|167234429 zinc finger and BTB domain containing 17 [Homo
sapiens]
Length = 803
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 15/180 (8%)
Query: 237 SSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKE-QTAPTGQGADIEADQ 295
S A TSPG GNA + R K+ ++ R + ++ P G D++ ++
Sbjct: 113 SLAEPATSPG---GNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEER 169
Query: 296 GGEAADS-----QREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAE 350
GG+A + Q E+A A RE + + A A+ E+++ + PA
Sbjct: 170 GGQAQSAASGAEQTEKADAP-REPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPAR 228
Query: 351 EGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAE--APADQGSEVTDNQR 408
+G E Q+E+ + PA+ + +G+ EA + E A D G E+ R
Sbjct: 229 KGEE---EQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEAR 285
>gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
Length = 265
Score = 47.0 bits (110), Expect = 4e-05
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 40/209 (19%)
Query: 292 EADQGGEAADSQREEAIADQRE------GAAGNQRAGAPADQGAEAADNQREEAADNQRA 345
E+ +G + ++++ + + Q++ G G +R + +AD Q + + + A
Sbjct: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSG----SSPSADQQGAQDREEEAA 72
Query: 346 GAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEA-PAD-----Q 399
AP AAD QR + + + A APA S HR E Q+ + PA +
Sbjct: 73 AAP------AADQQRAQDREEEAAAAPAPTSS----GHRTEKRKPQQPQCRPAGGTGQRR 122
Query: 400 GSEVTDNQREEAVHDQRERAPAVQGADN--------------QRAQARAGQRAEAAHNQR 445
GS + + ++ D+ E A A + +R A GQR + +
Sbjct: 123 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPS 182
Query: 446 AGAPGIQEAEVSAAQGTTGTAPGARARKQ 474
A G Q+ E AA T+ G R K+
Sbjct: 183 ADQQGAQDREEEAAAAPVPTSRGHRTEKR 211
Score = 42.7 bits (99), Expect = 8e-04
Identities = 61/247 (24%), Positives = 89/247 (36%), Gaps = 43/247 (17%)
Query: 200 QVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQ 259
Q + G +RR G +P A + + A E A + A + DR A P
Sbjct: 42 QPAGGTGQRRGSGSSPSA-----DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPT 96
Query: 260 ASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQ 319
+S R R+ ++ Q P G +AD Q + D+ E AA
Sbjct: 97 SSGHRTEK-------RKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQ---DREEEAAA-- 144
Query: 320 RAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQG 379
A AP +G + ++ AG G+ R+ ADQ QG
Sbjct: 145 -APAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGS--------------RSSPSADQ--QG 187
Query: 380 TDNHREEAADNQRAEAPADQGSEVTDNQREE------AVHDQRERAPAVQGADNQRAQAR 433
+ EEAA A P +G +R++ A QR + + AD QRAQ R
Sbjct: 188 AQDREEEAA---AAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDR 244
Query: 434 AGQRAEA 440
+ A A
Sbjct: 245 EEEAAAA 251
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 25/151 (16%)
Query: 399 QGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEA----AHNQRAGAPGIQEA 454
+GS + + ++ D+ E A A AD QRAQ R + A A + R Q+
Sbjct: 51 RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQP 110
Query: 455 EVSAAQGT-----TGTAP-----GARARKQVKTVRFQTPGRFSWFCKRRRAFWHTPRLPT 504
+ A GT +G++P GA+ R++ P S R R P
Sbjct: 111 QCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAA---APAPTS------RGHRTEKRKPQ 161
Query: 505 LPKRVPRAGEARNLRVLRAEARAEAEQGEQE 535
P+R P AG + R R+ A+ +QG Q+
Sbjct: 162 QPQRRPAAGTGQR-RGSRSSPSAD-QQGAQD 190
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/173 (23%), Positives = 68/173 (39%), Gaps = 18/173 (10%)
Query: 292 EADQGGEAADSQREEAIAD--QREGAAGNQRAGAPADQGAEAADNQREEAA-DNQRAGAP 348
EA++ GEA D R +A+ + Q A GN +A ++ E A N A+ +Q+ P
Sbjct: 138 EAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGP 197
Query: 349 AEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQR 408
EG +Q + + P Q + + EE A+ P ++G V N
Sbjct: 198 QAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPH 257
Query: 409 EEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQG 461
+ + + + R+EA AG PG +EA+ +G
Sbjct: 258 PSLGYKEIRKGES---------------RSEALAVDGAGKPGAEEAQDPEGKG 295
Score = 30.0 bits (66), Expect = 5.6
Identities = 31/158 (19%), Positives = 60/158 (37%), Gaps = 26/158 (16%)
Query: 331 AADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAP--------------ADQR 376
A +E A ++ +E +E +NQ +A + E P A++
Sbjct: 83 ALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKS 142
Query: 377 SQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQ 436
+ TD R +A E+ A+ ++ + EE PA + +Q G
Sbjct: 143 GEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPA-----SLPSQKYPGP 197
Query: 437 RAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQ 474
+AE + G+ + V +G + PG +A+++
Sbjct: 198 QAE------GDSEGLSQGLVDREKGLS-AEPGWQAKRE 228
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 46.6 bits (109), Expect = 6e-05
Identities = 86/457 (18%), Positives = 167/457 (36%), Gaps = 47/457 (10%)
Query: 60 EKSTPHPPQPPKKPKEPRVRRRVQQMVTP-----PPRLVVG-TYDSSNASDSEFSDFETS 113
+ S+ P +KPK V + Q P P++ G SS++S S S ++
Sbjct: 172 DSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Query: 114 RDKSRQGPR----RGKKVRKMPVSYLGS---KFLGSDLESEDDEELVEAFLRRQE----- 161
+K+ P+ + + V K PV + K S+ S D+EE + ++ +
Sbjct: 232 EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 162 -KQPSAPPARRRVNLPVPMFEDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPG 220
PSAPP ++ + P + ++ + S + K K +A
Sbjct: 292 VPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
Query: 221 VGEA-RLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRK 279
A + A ++ +S+ S+ + +P G + A + P + A+ ++
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTK-SPAVKPAAAPKQ-- 408
Query: 280 EQTAPTGQGADI---EADQGGEAADSQREEAIADQREGAAGNQRAGAPAD---QGAEAAD 333
P G G + +AD +S E ++ A +A A A +A
Sbjct: 409 ----PVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ 464
Query: 334 NQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRA 393
R+ ++D+ ++ + EE + + + G + +A +A
Sbjct: 465 GSRDSSSDSD----------SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKA 514
Query: 394 EAPADQGSEVTDNQREEAVHDQ---RERAPAVQGADNQRAQ-ARAGQRAEAAHNQRAGAP 449
E+ S+ + + EE + + R +AP G AQ +A + +E ++ A
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574
Query: 450 GIQEAEVSAAQGTTGTAPGARARKQVKTVRFQTPGRF 486
+ S + A Q K ++ QTP F
Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTF 611
Score = 40.4 bits (93), Expect = 0.004
Identities = 87/492 (17%), Positives = 174/492 (35%), Gaps = 47/492 (9%)
Query: 69 PPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKS--RQGPRRGKK 126
P KK P R + PP + +SS++ +S D E + K ++G + K
Sbjct: 101 PAKKAAVPAKR-----VGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAK 155
Query: 127 VRKMPVSYLGSKFLGSDLESEDDE------ELVEAFLRRQEKQPSAPP--ARRRVNLPVP 178
K P S SD SED+ ++ ++ Q K P P A + N
Sbjct: 156 AAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAA 215
Query: 179 MFEDNLGPQLSKADRWREYVSQVSWGKL-KRRVKGWAPRAGPGVGEARLASTAVESAGVS 237
+ S D E + + K++V AP R +S++ +S+
Sbjct: 216 SSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP-VKAATTPTRKSSSSEDSSSDE 274
Query: 238 SAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRR---KEQTAPTGQGADIEAD 294
+ ++ G V P A P PK + + ++ K+Q + + + E+D
Sbjct: 275 EEEQKKPMKNKPGPYSSVPPPSAPP----PKKSLGTQPPKKAVEKQQPVESSEDSSDESD 330
Query: 295 QGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAE 354
E +A+ + + A + + +D+ ++ A ++ AG +
Sbjct: 331 SSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390
Query: 355 AADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHD 414
A + A + A Q G AD+ +E ++ S + + ++ V
Sbjct: 391 PAVTTKSPAV---KPAAAPKQPVGGGQKLLTRKADSSSSE---EESSSSEEEKTKKMVAT 444
Query: 415 QRERAPAVQGADNQRAQARAGQRAEAA---------HNQRAGAPGIQEAEVSAAQGTTGT 465
+ +A A QA G R ++ ++ +++ A G +
Sbjct: 445 TKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPS 504
Query: 466 APGARARKQVKTVRFQTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEA 525
P + + + ++ + S + + +PR P+A +A L A+
Sbjct: 505 KPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPR--------PQAPKANGTSALTAQN 556
Query: 526 RAEAEQGEQEDQ 537
A+ E+E++
Sbjct: 557 GKAAKNSEEEEE 568
Score = 39.7 bits (91), Expect = 0.007
Identities = 84/442 (19%), Positives = 150/442 (33%), Gaps = 55/442 (12%)
Query: 13 IPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIMEKSTPHPPQPPKK 72
+P++ +A + + P K + + + EE+ + +++ P PPKK
Sbjct: 243 VPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKK 302
Query: 73 PKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQGPRR---GKKVRK 129
+ T PP+ V +S+ + ++S ++ ++ P + K K
Sbjct: 303 -----------SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
Query: 130 MPVSYLG--SKFLGSDLESEDDEELVEAFLRRQEKQPSAP------PARRRVNLPVPMFE 181
P + S SD +S +D+E + + P PA + P
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG 411
Query: 182 DNLGPQLSKAD--RWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSA 239
KAD E S K K+ V P+A + A A + + SS+
Sbjct: 412 GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS 471
Query: 240 PEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEA 299
+S + + P++ A K +A G+ E+ +
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQK------VAGGAAPSKPASAKKGKA---ESSNSSSS 522
Query: 300 ADSQREEAIADQREGAAGNQRAGAP--------ADQGAEAADNQREEAADNQRAGAPAEE 351
DS EE +++ G+ R AP Q +AA N EE + ++A +
Sbjct: 523 DDSSEEE---EEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSK 579
Query: 352 GAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAP--------ADQGSEV 403
++ EAA + Q + + +RA +P + S V
Sbjct: 580 SGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRV 639
Query: 404 TDNQ---REEAVHDQRERAPAV 422
DN + A D ERA V
Sbjct: 640 ADNSFDAKRGAAGDWGERANQV 661
Score = 35.4 bits (80), Expect = 0.13
Identities = 64/320 (20%), Positives = 112/320 (35%), Gaps = 37/320 (11%)
Query: 101 NASDSEFSDFETSRDKSRQGPRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQ 160
+A+ S D + KS + P R K PV+ K S +SED E +
Sbjct: 44 DANASSLLDIYSFWLKSAKVPER-KLQANGPVAKKAKKKASSS-DSEDSSE--------E 93
Query: 161 EKQPSAPPARRRVNLPVPMFEDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPG 220
E++ PPA++ VP L P + A S+ S + P
Sbjct: 94 EEEVQGPPAKKAA---VPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGV 150
Query: 221 VGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKE 280
+A+ A + A S + +S D P+ +PKI + + + K
Sbjct: 151 KPQAKAAKAPPKKAKSSDSDSDSSSEDE------------PPKNQKPKITPVTVKAQTKA 198
Query: 281 QTAPTGQGADIEADQGGEAADSQREEAIAD--QREGAAGNQRAGAPADQGAEAADNQREE 338
P I + ++ S + +D + E AA + P Q A +
Sbjct: 199 PPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKA-- 256
Query: 339 AADNQRAGAPAEEGAEAADNQREEAADNQRA--------EAPADQRSQGTDNHREEAADN 390
A R + +E+ + + ++++ N+ AP ++S GT ++
Sbjct: 257 ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQ 316
Query: 391 QRAEAPADQGSEVTDNQREE 410
Q E+ D E + EE
Sbjct: 317 QPVESSEDSSDESDSSSEEE 336
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 21/182 (11%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAA---------GNQRAG---A 323
+ RK++ G + + + G+ ++ + A AD REG G QR
Sbjct: 2035 QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVG 2094
Query: 324 PADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNH 383
P ++ E D Q + D +R + D R D R + S+ D +
Sbjct: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDK----DSSRDWDRN 2150
Query: 384 REEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHN 443
RE +A+ R E AD+G E D RE + + +RER + D R+++R R +A
Sbjct: 2151 RERSANRDR-EREADRGKE-WDRSRERSRNRERERD---RRRDRDRSRSRERDRDKARDR 2205
Query: 444 QR 445
+R
Sbjct: 2206 ER 2207
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/162 (17%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 317 GNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQR 376
G++R G D+ A + +E +++ G+ E G+ + +++ +N+ D
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED-- 208
Query: 377 SQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQ 436
+ E D + E + G E + + EE ++ E Q +Q+ +
Sbjct: 209 ---VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
Query: 437 RAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTV 478
A + + + + V + GT G+ + RK+ + +
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGI 307
Score = 37.4 bits (85), Expect = 0.035
Identities = 30/163 (18%), Positives = 61/163 (37%), Gaps = 17/163 (10%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
RR K T + +E D+ + +E + + G+ + +D+ +N+
Sbjct: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENE 201
Query: 336 REEAADNQRAGAPAEEGAEA----------------ADNQREEAADNQRAEAPADQRSQG 379
E ++ EE AE + + EE + + + DQ+ +G
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 380 TD-NHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPA 421
D + R EA+D+ GS + + + + ++ER A
Sbjct: 262 NDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRA 304
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/162 (17%), Positives = 64/162 (39%), Gaps = 5/162 (3%)
Query: 317 GNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQR 376
G++R G D+ A + +E +++ G+ E G+ + +++ +N+ D
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED-- 208
Query: 377 SQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQ 436
+ E D + E + G E + + EE ++ E Q +Q+ +
Sbjct: 209 ---VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
Query: 437 RAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTV 478
A + + + + V + GT G+ + RK+ + +
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGI 307
Score = 37.4 bits (85), Expect = 0.035
Identities = 30/163 (18%), Positives = 61/163 (37%), Gaps = 17/163 (10%)
Query: 276 RRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQ 335
RR K T + +E D+ + +E + + G+ + +D+ +N+
Sbjct: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENE 201
Query: 336 REEAADNQRAGAPAEEGAEA----------------ADNQREEAADNQRAEAPADQRSQG 379
E ++ EE AE + + EE + + + DQ+ +G
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 380 TD-NHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPA 421
D + R EA+D+ GS + + + + ++ER A
Sbjct: 262 NDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRA 304
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 45.1 bits (105), Expect = 2e-04
Identities = 49/229 (21%), Positives = 78/229 (34%), Gaps = 16/229 (6%)
Query: 208 RRVKGWAPRA-GPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWR 266
R VKGW PR G G+G R V S + TS D P P R R
Sbjct: 182 RTVKGWRPRRLGGGLGGTRRGGADVNIR--HSGRDDTSRYDERPG------PSPLPHRDR 233
Query: 267 PKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPAD 326
+ R R +E+ + D+ + +EE + ++ +
Sbjct: 234 DRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSS 293
Query: 327 QGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREE 386
+ E A +RE + + G E +EA D ++ P + G D E+
Sbjct: 294 RSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG-------PPGELGPDGPDGPEEK 346
Query: 387 AADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAG 435
D R + + R+ RE +G++ R +AR G
Sbjct: 347 GRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGG 395
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/203 (22%), Positives = 89/203 (43%), Gaps = 27/203 (13%)
Query: 279 KEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAP----ADQGAEAADN 334
+E+ A +G + E + EA + E E A+ + A +P A AEA
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 335 QREEAADN------QRAGAPAEEGA----EAADNQREEAADNQRAEAPADQRSQGTDNHR 384
++EEA ++A +PA+E A EA ++EEA ++P +S + +
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 385 EEAADN----------QRAEAPADQGSEVTDNQRE--EAVHDQRERAPAVQGADNQRAQA 432
A + A++PA+ S V + + E ++ ++P + A + +A
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE-KA 652
Query: 433 RAGQRAEAAHNQRAGAPGIQEAE 455
++ ++ EA ++A +P EA+
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAK 675
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/197 (23%), Positives = 96/197 (48%), Gaps = 27/197 (13%)
Query: 279 KEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGA----EAADN 334
KE +P + EA EA ++EEA + ++A +PA + A EA
Sbjct: 514 KEAKSPVKE----EAKSPAEAKSPEKEEAKSPAE--VKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 335 QREEAADN------QRAGAPAEEGA----EAADNQREEAADNQRAEAPADQRSQGTDNHR 384
++EEA ++A +PA+E A EA ++ ++ + A++PA+ +S + +
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 385 E--EAADNQRAEAPADQGSEVTDN----QREEAVHDQRERAPAVQGADNQRAQARAGQRA 438
E ++A++P + ++ + ++EEA ++ ++P V+ +A++ +A
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP-VKAEAKSPEKAKSPVKA 686
Query: 439 EAAHNQRAGAPGIQEAE 455
EA ++A +P +EA+
Sbjct: 687 EAKSPEKAKSPVKEEAK 703
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/211 (18%), Positives = 86/211 (40%), Gaps = 11/211 (5%)
Query: 279 KEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRA--GAPADQGA----EAA 332
+EQT T ++ ++ EA + + +E + E A G + PA++ A EA
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 333 DNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQR 392
+EEA A +P +E A++ E ++A++PA + ++ + + +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSP----AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573
Query: 393 AEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQ 452
+ A + +EEA ++P + + +A++ A++ + A +P
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 453 EAEVSAAQGTTGTAPGARARKQVKTVRFQTP 483
++ A T A K + ++P
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/387 (17%), Positives = 146/387 (37%), Gaps = 34/387 (8%)
Query: 53 EDVARIMEKSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFET 112
E+ +++EKS ++ +E +V V + + G + + E
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Query: 113 SRDKSRQGPRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQEKQPSAPPARRR 172
++ + +K K PV E+ + EA +E+ S +
Sbjct: 501 TKSPPAEEAASPEKEAKSPVK-------------EEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 173 VNLPVPMFEDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARL---AST 229
P E+ P +K+ E S K + K A EA+ A +
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV-KSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 230 AVESAGVSSAPEGTSPGDRLGNAGDVCVPQA--SPRRWRPKINWASFRRRRKEQTAPTGQ 287
V+ S A + + + +V P+ SP + K + ++E +P
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 288 GADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQR----EEAADNQ 343
+ ++A+ E+A + + A ++A +P + A++ + + EEA +
Sbjct: 667 KSPVKAEA------KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 344 RAGAPAEEGAEAADNQR----EEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQ 399
+A +P +E A+ + + EEA ++A++P ++ + + + A +PAD+
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Query: 400 GSEVTDNQ-REEAVHDQRERAPAVQGA 425
E + +EE ++ ++P + A
Sbjct: 781 FPEKAKSPVKEEVKSPEKAKSPLKEDA 807
Score = 33.5 bits (75), Expect = 0.50
Identities = 89/502 (17%), Positives = 174/502 (34%), Gaps = 49/502 (9%)
Query: 16 EVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIMEKSTPHPPQPPKKPKE 75
E GG S PA + A + ++EE ++ + A+ EK P K P++
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE-AKSPEKEEAKSPAEVKSPEK 549
Query: 76 PRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQGPRRGKKVRKMPVSYL 135
+ + + P + S A ++ + + P K K
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 136 GSKFLGSDLESEDDEEL---VEAFLRRQEKQPSAPPARRRVNLPVPMFEDNLGPQLSKAD 192
++ +S EE E + K P+ A+ P E+ P+ +K+
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669
Query: 193 RWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNA 252
E S K K VK A + + + E A E SP
Sbjct: 670 VKAEAKSPE---KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA---K 723
Query: 253 GDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEA--------DQGGEAADSQR 304
V +P + + + + + K ++ + D+++ ++ AD
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEA-KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782
Query: 305 EEAIADQREGAAGNQRAGAPADQGAEAADNQ------------REEAADNQRAGAP---A 349
E+A + +E ++A +P + A+A + + EE + P A
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 350 EEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQRE 409
EE A + EE D+++ EAP + + ++E A + E+ + E +++++
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 410 EAVHDQRERAPA-------------VQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEV 456
V + APA + A + A+A + ++ A + A E
Sbjct: 903 --VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 457 SAAQGTTGTAPGARARKQVKTV 478
A + A+A++ KT+
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTL 982
Score = 30.8 bits (68), Expect = 3.3
Identities = 33/172 (19%), Positives = 72/172 (41%), Gaps = 15/172 (8%)
Query: 298 EAADSQREEAIADQREGAAGNQRAGAPADQGAEA-ADNQREEAADNQRAGAPAEEGAEAA 356
E DS++EEA + ++ ++ E+ + ++EEA D ++ P +E A A
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE-APAK 913
Query: 357 DNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQR 416
+E+A ++ E + + A+ + A AP E D + E+A +
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA-AP-----EKKDTKEEKAKKPEE 967
Query: 417 ERAPAVQGADNQRAQARAGQRAEA-------AHNQRAGAPGIQEAEVSAAQG 461
+ + ++ + ++ + +A + +Q+ P + E AA+G
Sbjct: 968 KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/248 (22%), Positives = 92/248 (37%), Gaps = 30/248 (12%)
Query: 219 PGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRR 278
P V A++ +++V + + +PG GDV PQ P A ++
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPG----KVGDV-TPQVKGGALPP----AKRAKKP 266
Query: 279 KEQTAPTGQGADIEADQ-GGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQRE 337
+E++ + +G++ E + G + + E I R AA G P A +
Sbjct: 267 EEESESSEEGSESEEEAPAGTRSQVKASEKILQVR--AASAPAKGTPGKGATPAPPGKAG 324
Query: 338 EAADNQRAGAPAEEGA----EAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQR- 392
A +AG P E+ E++D++ E A +A A ++ A ++ R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 393 ------------AEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEA 440
A A A G D+Q D E APA + Q RA A A
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS-APA 443
Query: 441 AHNQRAGA 448
+ R GA
Sbjct: 444 KESPRKGA 451
Score = 35.8 bits (81), Expect = 0.10
Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 25/281 (8%)
Query: 261 SPRRW-RPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQ 319
SPR+ P N +E + P A ADS E+ + E +
Sbjct: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
Query: 320 RAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQG 379
+ PA +A+ +E+ + A AP + G + +RA+ P ++
Sbjct: 216 PSVKPAQ--VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS 273
Query: 380 TDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAE 439
EE ++++ EAPA S+V + E+ + + APA A G+
Sbjct: 274 -----EEGSESEE-EAPAGTRSQVKAS--EKILQVRAASAPAKGTPGKGATPAPPGKAGA 325
Query: 440 AAHNQRAGAPGIQEAEVSAAQGTTG--TAPGARARKQVKTVRFQTPGRFSWFCKRRRAFW 497
A +AG P +++E S+ + + P A+A Q K G+ S
Sbjct: 326 VASQTKAGKPE-EDSESSSEESSDSEEETPAAKALLQAK-----ASGKTSQVGAASAPAK 379
Query: 498 HTPRLPTLPKRVPRAGEARNLRVLRAEA--RAEAEQGEQED 536
+PR P + G A V +A+A R E Q E+
Sbjct: 380 ESPRKGAAPAPPGKTGPA----VAKAQAGKREEDSQSSSEE 416
Score = 33.9 bits (76), Expect = 0.39
Identities = 31/170 (18%), Positives = 67/170 (39%), Gaps = 14/170 (8%)
Query: 287 QGADIEADQGGEAADSQREEAIADQREGAAGN---------QRAGAPADQGAEAADNQRE 337
+ ++ +++ +++D + A+A +E + GN G P G A + E
Sbjct: 543 EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
Query: 338 EAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPA 397
+ DN + +EE +++AD++ AA PA + Q ++ AP
Sbjct: 603 KPMDNSES---SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659
Query: 398 DQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAG 447
G++ ++ +PAV G + A+ + + ++ G
Sbjct: 660 RVGTQAP--RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Score = 33.9 bits (76), Expect = 0.39
Identities = 46/249 (18%), Positives = 92/249 (36%), Gaps = 38/249 (15%)
Query: 217 AGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRR 276
A V R+ + A AG +++P G+SP G
Sbjct: 652 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT------------------------- 686
Query: 277 RRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQG-AEAADNQ 335
+R + + + + +D E ++ G A + +++ + A + QG A +
Sbjct: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 336 REEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEA 395
+A E E +++ EE+ + A +PA ++ + + A+ A A
Sbjct: 747 TGPTVTQVKA-----EKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARA 799
Query: 396 PADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAE 455
P+ +G+ + A ++R+P+ + R Q + A P + +A
Sbjct: 800 PSAKGTISAPGKVVTAAAQAKQRSPS-----KVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 456 VSAAQGTTG 464
+AAQ TG
Sbjct: 855 ATAAQAQTG 863
Score = 32.7 bits (73), Expect = 0.86
Identities = 52/266 (19%), Positives = 87/266 (32%), Gaps = 23/266 (8%)
Query: 279 KEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREE 338
K + + ++ E+D AA + + + + A A AP+ +G +A +
Sbjct: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
Query: 339 AADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPAD 398
AA + +P++ + Q A P+ ++ T A A
Sbjct: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT-------------AAQAQ 861
Query: 399 QGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGA----PGIQEA 454
G E EE + E Q + + A A + R GA PG +
Sbjct: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG--KT 919
Query: 455 EVSAAQGTTGTAPGARARKQVKTVRFQTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGE 514
SAAQ G+ + + + K F R P P P +
Sbjct: 920 GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 979
Query: 515 A----RNLRVLRAEARAEAEQGEQED 536
A R R + AR+ + + E ED
Sbjct: 980 AASTPRKARASESTARSSSSESEDED 1005
Score = 29.6 bits (65), Expect = 7.3
Identities = 31/164 (18%), Positives = 60/164 (36%), Gaps = 11/164 (6%)
Query: 316 AGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEG-------AEAADNQREEAADNQR 368
A + G D G+ ++ EE A+ P+ + A A ++ R+ AA
Sbjct: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
Query: 369 AEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQ--REEAVHDQRERAPAVQGAD 426
+ G + + + ++ +++ + + VT Q + + R+PA A
Sbjct: 917 GKTGPSAAQAGKQD--DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAAT 974
Query: 427 NQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGAR 470
+AQA + R A A + + + T PG R
Sbjct: 975 PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,105,804
Number of Sequences: 37866
Number of extensions: 1223931
Number of successful extensions: 9423
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 480
Number of HSP's that attempted gapping in prelim test: 7158
Number of HSP's gapped (non-prelim): 1887
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.