Guide to the Human Genome
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Name: NEFH Sequence: fasta or formatted (1020aa) NCBI GI: 32483416
Description:

neurofilament, heavy polypeptide 200kDa

Referenced in:

Cytoskeleton
Neurons

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            14.1        144           3
 C cysteine            0.4          4           1
 D aspartate           3.2         33           2
 E glutamate          18.4        188           4
 F phenylalanine       1.0         10           1
 G glycine             3.8         39           3
 H histidine           1.1         11           2
 I isoleucine          1.6         16           1
 K lysine             16.2        165           3
 L leucine             4.9         50           2
 M methionine          0.9          9           2
 N asparagine          0.6          6           1
 P proline             8.0         82           2
 Q glutamine           3.6         37           3
 R arginine            4.3         44           2
 S serine              8.5         87           3
 T threonine           3.4         35           2
 V valine              4.8         49           2
 W tryptophan          0.3          3           1
 Y tyrosine            0.8          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neurofilament, heavy polypeptide 200kDa 
NEFM                  0.257   neurofilament, medium polypeptide 150kDa isoform 1 ...
INA                   0.164   internexin neuronal intermediate filament protein, a...
NEFL                  0.143   neurofilament, light polypeptide 68kDa 
VIM                   0.139   vimentin 
DES                   0.133   desmin 
GFAP                  0.125   glial fibrillary acidic protein isoform 1 
PRPH                  0.124   peripherin 
GFAP                  0.124   glial fibrillary acidic protein isoform 2 
NEFM                  0.100   neurofilament, medium polypeptide 150kDa isoform 2 ...
KRT8                  0.088   keratin 8 
KRT7                  0.083   keratin 7 
KRT17                 0.081   keratin 17 
KRT75                 0.079   keratin 75 
KRT12                 0.078   keratin 12 
KRT14                 0.077   keratin 14 
TTN                   0.076   titin isoform N2-A 
KRT19                 0.076   keratin 19 
KRT6C                 0.075   keratin 6C 
KRT84                 0.075   keratin, hair, basic, 4 
KRT5                  0.075   keratin 5 
KRT3                  0.075   keratin 3 
KRT15                 0.075   keratin 15 
KRT6B                 0.075   keratin 6B 
KRT6A                 0.075   keratin 6A 
TRDN                  0.075   triadin 
KRT76                 0.074   keratin 76 
KRT13                 0.074   keratin 13 isoform a 
KRT85                 0.073   keratin 85 
LOC100293351          0.072   PREDICTED: hypothetical protein isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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