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Search of human proteins with 194097386
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1
[Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 976 0.0
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 668 0.0
gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Hom... 556 e-158
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 330 1e-90
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 330 1e-90
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 322 6e-88
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 318 7e-87
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 311 6e-85
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 302 4e-82
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 287 1e-77
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 275 5e-74
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 275 7e-74
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 7e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 7e-74
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 273 3e-73
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 268 1e-71
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 266 3e-71
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 262 6e-70
gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precur... 262 6e-70
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 253 3e-67
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 252 6e-67
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 251 1e-66
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 250 2e-66
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 248 9e-66
gi|4504023 glycine receptor, beta [Homo sapiens] 246 4e-65
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 241 8e-64
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 241 1e-63
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 241 1e-63
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 237 2e-62
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 233 4e-61
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 976 bits (2523), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI 60
MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI
Sbjct: 1 MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI 60
Query: 61 LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM 120
LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM
Sbjct: 61 LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM 120
Query: 121 TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV 180
TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV
Sbjct: 121 TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV 180
Query: 181 QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD 240
QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD
Sbjct: 181 QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD 240
Query: 241 ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW 300
ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW
Sbjct: 241 ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW 300
Query: 301 VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL 360
VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL
Sbjct: 301 VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL 360
Query: 361 EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP 420
EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP
Sbjct: 361 EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP 420
Query: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 479
DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
Sbjct: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 479
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 668 bits (1724), Expect = 0.0
Identities = 331/445 (74%), Positives = 380/445 (85%), Gaps = 7/445 (1%)
Query: 41 RPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVG 100
+P+R+R + K S + +++ D+TK K +QLLR+D+HDFSMRP FGGPAIPVG
Sbjct: 47 KPKRKRWTGQVEMPKP-SHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVG 105
Query: 101 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFF 160
VDVQVESLDSISEVDMDFTMTLYLRHYWKDERL+F S +N SMTFDGRLVKKIWVPD+FF
Sbjct: 106 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFF 165
Query: 161 VHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYA 220
VHSKRSF HDTTTDN+MLRV PDG VLYS+R+TVTAMCNMDFS FPLD+QTCSLE+ESYA
Sbjct: 166 VHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYA 225
Query: 221 YTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRH 280
YT++DLMLYWK G++SLKTDE+ISLSQFLIQ+FHTT++LAFYSSTGWYNRLYINFTLRRH
Sbjct: 226 YTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRH 285
Query: 281 IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSY 340
IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARV LGITTVLTM+TIITGVNASMPRVSY
Sbjct: 286 IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSY 345
Query: 341 IKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGN 400
+KAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE+KLREK PC G+ +T MLDG+
Sbjct: 346 VKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGS 405
Query: 401 YSDGEVNDLDNY----MPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRI--DTHA 454
YS+ E N L Y + E+ D+++V L L+ E ++ ++K RI +THA
Sbjct: 406 YSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHA 465
Query: 455 IDKYSRIIFPAAYILFNLIYWSIFS 479
IDKYSR+IFPA+YI FNLIYWS+FS
Sbjct: 466 IDKYSRLIFPASYIFFNLIYWSVFS 490
>gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Homo
sapiens]
Length = 467
Score = 556 bits (1433), Expect = e-158
Identities = 275/418 (65%), Positives = 325/418 (77%), Gaps = 2/418 (0%)
Query: 63 RSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTL 122
+ D TK+ K EQLL I+D+DF+MRPGFGG +PVG+DV VES+DSISE +MDFTMT
Sbjct: 49 KKDDSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTF 108
Query: 123 YLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQP 182
YLRHYWKDERLSFPST N SMTFD RL +KIWVPD+FFVHSKRSFIHDTT +N+MLRV P
Sbjct: 109 YLRHYWKDERLSFPSTANKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHP 168
Query: 183 DGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDER 242
DG VL SLR+TV+AMC MDFSRFPLDTQ CSLE+ESYAY EDDLMLYWK GN SL T+E
Sbjct: 169 DGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEH 228
Query: 243 ISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVS 302
+SLSQF I++F ++ LAFYSSTGWYNRL+INF LRRH+FFF+LQTYFPA LMVMLSWVS
Sbjct: 229 MSLSQFFIEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVS 288
Query: 303 FWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEY 362
FWIDRRAVPARV LGITTVLTMSTIIT V+ASMP+VSY+KAVD+YLWVS +FVFLSV+EY
Sbjct: 289 FWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEY 348
Query: 363 AAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDR 422
AAVNYLTTV+ERK+ K K+ + + DG Y D E++ + N E R
Sbjct: 349 AAVNYLTTVEERKQFKKTGKISRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDFMR 408
Query: 423 MMVQLTLASERSSPQRKSQRSSYVSMRI--DTHAIDKYSRIIFPAAYILFNLIYWSIF 478
+ +++ S +R+ +V I + H ID YSRI+FP YILFNL YW ++
Sbjct: 409 RKSICSPSTDSSRIKRRKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVY 466
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 330 bits (847), Expect = 1e-90
Identities = 176/423 (41%), Positives = 268/423 (63%), Gaps = 33/423 (7%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + YW+D+RL++ S L++
Sbjct: 48 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY-SGIPLNL 106
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ ++WVPD +F++ K+SF+H T N M+R+ PDG VLY LR+T TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
R+PLD Q C+LEIESY YT DD+ YW+ G+ ++ ERI L QF I E ++ +
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVF- 225
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
+TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV LGITTVLT
Sbjct: 226 ATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 285
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKEQKLREK 382
M+TI T + ++P++ Y+KA+D+YL FVFVFL++LEYA VNY+ + ++++KL EK
Sbjct: 286 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEK 345
Query: 383 LPC---------TSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP---DRMMVQLTLA 430
++ + +L E+N++ + + D +Q
Sbjct: 346 TAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQ 405
Query: 431 S-----------ERSSPQRKS---QRSSYVSMRI----DTHAIDKYSRIIFPAAYILFNL 472
S +RS P +K+ +RSS + ++I D +AID++SRI+FP + LFNL
Sbjct: 406 SMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNL 465
Query: 473 IYW 475
+YW
Sbjct: 466 VYW 468
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 330 bits (847), Expect = 1e-90
Identities = 176/423 (41%), Positives = 268/423 (63%), Gaps = 33/423 (7%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + YW+D+RL++ S L++
Sbjct: 48 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY-SGIPLNL 106
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ ++WVPD +F++ K+SF+H T N M+R+ PDG VLY LR+T TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
R+PLD Q C+LEIESY YT DD+ YW+ G+ ++ ERI L QF I E ++ +
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVF- 225
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
+TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV LGITTVLT
Sbjct: 226 ATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 285
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKEQKLREK 382
M+TI T + ++P++ Y+KA+D+YL FVFVFL++LEYA VNY+ + ++++KL EK
Sbjct: 286 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEK 345
Query: 383 LPC---------TSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP---DRMMVQLTLA 430
++ + +L E+N++ + + D +Q
Sbjct: 346 TAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQ 405
Query: 431 S-----------ERSSPQRKS---QRSSYVSMRI----DTHAIDKYSRIIFPAAYILFNL 472
S +RS P +K+ +RSS + ++I D +AID++SRI+FP + LFNL
Sbjct: 406 SMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNL 465
Query: 473 IYW 475
+YW
Sbjct: 466 VYW 468
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 322 bits (824), Expect = 6e-88
Identities = 174/428 (40%), Positives = 260/428 (60%), Gaps = 41/428 (9%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + W+D+RLS+ + L++
Sbjct: 47 YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY-NVIPLNL 105
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ ++WVPD +F++ K+SF+H T N M+R+ PDG VLY LR+T TA C MD
Sbjct: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
R+PLD Q C+LEIESY YT DD+ YW+ ++++ +I L QF I ++ TK +
Sbjct: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVF- 224
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
STG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV LGITTVLT
Sbjct: 225 STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKL 383
M+TI T + ++P++ Y+KA+D+YL FVFVF+++LEYA VNY+ + + QK +
Sbjct: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEK 344
Query: 384 PCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGE-----------KPDRMMVQLTLAS- 431
++ R LD N D N L + + E P M+ +S
Sbjct: 345 AASANNEKMR---LDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSI 401
Query: 432 -----------------ERSSPQRKS---QRSSYVSMRI----DTHAIDKYSRIIFPAAY 467
ER Q+KS +R+S + + I D +AID++SRI FP +
Sbjct: 402 QYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVF 461
Query: 468 ILFNLIYW 475
FN++YW
Sbjct: 462 SFFNIVYW 469
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 318 bits (815), Expect = 7e-87
Identities = 175/431 (40%), Positives = 252/431 (58%), Gaps = 48/431 (11%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGGP + VG+ + V S+D +SEV+MD+T+T+Y + WKD+RLS+ S L++
Sbjct: 48 YDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSY-SGIPLNL 106
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ ++WVPD +F++ K+SF+H T N M+R+ PDG VLY LR+T TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
R+PLD Q C+LEIESY YT DD+ YW G ++ +I L QF I ++ +K ++
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFT 226
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
TG Y RL ++F L+R+I +F+LQTY P+TL+ +LSWVSFWI+ A ARV LGITTVLT
Sbjct: 227 -TGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLT 285
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNY---------------- 367
M+TI T + ++P++ Y+KA+DIYL FVFVFL++LEYA VNY
Sbjct: 286 MTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQD 345
Query: 368 -----------------------LTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDG 404
L+T++ R E E L S P+ M YS
Sbjct: 346 QSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVS---DPKATM----YSYD 398
Query: 405 EVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFP 464
+ + E R + + + S+ +R SQ + D ++IDK+SR+ FP
Sbjct: 399 SASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFP 458
Query: 465 AAYILFNLIYW 475
+ LFN++YW
Sbjct: 459 ITFSLFNVVYW 469
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 311 bits (798), Expect = 6e-85
Identities = 153/401 (38%), Positives = 247/401 (61%), Gaps = 11/401 (2%)
Query: 87 SMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFD 146
+ RPG GGP + V + ++V S+D ISE +M++TMT++L W+D RLS+ TN ++ D
Sbjct: 54 NFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNE-TLGLD 112
Query: 147 GRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFP 206
R V K+W+PD F V++K ++ HD T +N ++R+QPDG +LYS+R+T T C+MD +++P
Sbjct: 113 SRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYP 172
Query: 207 LDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTG 266
+D Q C L++ESY Y+ +D++ YW + + + +++ L+QF I + TT+L + S G
Sbjct: 173 MDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAG 232
Query: 267 WYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMST 326
+ RL ++F LRR+ +++Q+Y P+ L+V +SWVSFWI + AVPARV LGITTVLTM+T
Sbjct: 233 QFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTT 292
Query: 327 IITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCT 386
++ +S+PR S IKA+D+Y W+ +VFVF +++EYA ++ RK+QK + K+
Sbjct: 293 LMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHF--NADYRKKQKAKVKVSRP 350
Query: 387 SGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMM-------VQLTLASERSSPQRK 439
R A++ + S V P +M V+ + + +
Sbjct: 351 RAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSG 410
Query: 440 SQRSSYVSMR-IDTHAIDKYSRIIFPAAYILFNLIYWSIFS 479
Q +R ID ID Y+R +FPAA+ N+IYW+ ++
Sbjct: 411 GQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAYA 451
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 302 bits (774), Expect = 4e-82
Identities = 142/295 (48%), Positives = 210/295 (71%), Gaps = 2/295 (0%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + W+D+RLS+ + L++
Sbjct: 47 YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY-NVIPLNL 105
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ ++WVPD +F++ K+SF+H T N M+R+ PDG VLY LR+T TA C MD
Sbjct: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
R+PLD Q C+LEIESY YT DD+ YW+ ++++ +I L QF I ++ TK +
Sbjct: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVF- 224
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
STG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV LGITTVLT
Sbjct: 225 STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQK 378
M+TI T + ++P++ Y+KA+D+YL FVFVF+++LEYA VNY+ + + QK
Sbjct: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
Score = 42.7 bits (99), Expect = 7e-04
Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 8/109 (7%)
Query: 368 LTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQL 427
L+T++ + E E + GL PR+ ML Y + +P + R ++
Sbjct: 406 LSTLEIKNEMATSEAV---MGLGDPRSTMLA--YDASSIQYRKAGLPRHSF--GRNALER 458
Query: 428 TLASERSSPQRK-SQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
+A ++S +R+ SQ + D +AID++SRI FP + FN++YW
Sbjct: 459 HVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYW 507
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 287 bits (735), Expect = 1e-77
Identities = 151/409 (36%), Positives = 242/409 (59%), Gaps = 41/409 (10%)
Query: 88 MRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDG 147
+RP FGG + + + + + S+ SISE +MD+T T+YLR W D+RL F N S T D
Sbjct: 52 LRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--NKSFTLDA 109
Query: 148 RLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPL 207
RLV+ +WVPD + V SK+SF+H+ T N ++R+ +G VLY+LR+T T CNMD S++P+
Sbjct: 110 RLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPM 169
Query: 208 DTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGW 267
DTQTC L++ES+ Y +D+ W +GNDS++ E + L+Q+ I+ + T + TG
Sbjct: 170 DTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRS-QQETGN 228
Query: 268 YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTI 327
Y RL + F LRR++ +F+L+TY P+T +V+LSWVSFWI +VPAR +G+TTVL+M+T+
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 328 ITGVNASMPRVS-YIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ----ERKEQKLREK 382
+ G S+P + +IKA+D+YL + F FVF ++LEYA +Y + Q +R K E+
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGTTKEVEE 348
Query: 383 LPCTSGLPPPRTAML-------------DGNYSDGEVNDLDNYMPENGEKPDRMMVQLTL 429
+ T+ + ++ + +YSD + D + EK R++ T+
Sbjct: 349 VSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVFREKMGRIVDYFTI 408
Query: 430 ASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIF 478
+ + +D YS+++FP ++L N+ YW+ +
Sbjct: 409 QNPSN--------------------VDHYSKLLFPLIFMLANVFYWAYY 437
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 5e-74
Identities = 151/416 (36%), Positives = 240/416 (57%), Gaps = 16/416 (3%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
+ P T SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 36 KQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 95
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + HD TTDN +LR+
Sbjct: 96 IFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIS 155
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+GKVLYS+R+T+T C MD FP+D QTC++++ES+ YT +DL+ W + ++ E
Sbjct: 156 KNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEW-LSDGPVQVAE 214
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QF+++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 215 GLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421
YAAVN+++ Q ++ +LR + R + + N M + D
Sbjct: 335 YAAVNFVSR-QHKEFLRLRRR--------QKRQNKEEDVTRESRFNFSGYGMGHCLQVKD 385
Query: 422 RMMVQLTLASERSSPQRKSQ--RSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
V+ T A+ P + + +V ID SR FP A+++FN+ YW
Sbjct: 386 GTAVKATPANPLPQPPKDGDAIKKKFVDR---AKRIDTISRAAFPLAFLIFNIFYW 438
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 275 bits (703), Expect = 7e-74
Identities = 151/421 (35%), Positives = 243/421 (57%), Gaps = 9/421 (2%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 30 RSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVN 89
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 90 IFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRIS 149
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W++ +++ +
Sbjct: 150 RNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVAD 208
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QF+++E + +TG + + F L R + ++L+Q Y P+ L+V+LSW+
Sbjct: 209 GLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWI 268
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 269 SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 328
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYM-PENGEKP 420
YAAVN+ V + ++ LR + P + +G N M P +
Sbjct: 329 YAAVNF---VSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAK 385
Query: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRI---DTHAIDKYSRIIFPAAYILFNLIYWSI 477
D + V+ S ++P +S ++ IDK SRI FP A+++FN+ YW I
Sbjct: 386 DGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWII 445
Query: 478 F 478
+
Sbjct: 446 Y 446
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (703), Expect = 7e-74
Identities = 150/416 (36%), Positives = 240/416 (57%), Gaps = 16/416 (3%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
+ P T SP ++L+ R +D +RP F GP + V ++ + S S++E MD+ +
Sbjct: 36 KQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVN 95
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + HD TTDN +LR+
Sbjct: 96 IFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIS 155
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+GKVLYS+R+T+T C MD FP+D QTC++++ES+ YT +DL+ W + ++ E
Sbjct: 156 KNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEW-LSDGPVQVAE 214
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QF+++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 215 GLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421
YAAVN+++ Q ++ +LR + R + + N M + D
Sbjct: 335 YAAVNFVSR-QHKEFLRLRRR--------QKRQNKEEDVTRESRFNFSGYGMGHCLQVKD 385
Query: 422 RMMVQLTLASERSSPQRKSQ--RSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
V+ T A+ P + + +V ID SR FP A+++FN+ YW
Sbjct: 386 GTAVKATPANPLPQPPKDGDAIKKKFVDR---AKRIDTISRAAFPLAFLIFNIFYW 438
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (703), Expect = 7e-74
Identities = 150/416 (36%), Positives = 240/416 (57%), Gaps = 16/416 (3%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
+ P T SP ++L+ R +D +RP F GP + V ++ + S S++E MD+ +
Sbjct: 36 KQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVN 95
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + HD TTDN +LR+
Sbjct: 96 IFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIS 155
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+GKVLYS+R+T+T C MD FP+D QTC++++ES+ YT +DL+ W + ++ E
Sbjct: 156 KNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEW-LSDGPVQVAE 214
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QF+++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 215 GLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421
YAAVN+++ Q ++ +LR + R + + N M + D
Sbjct: 335 YAAVNFVSR-QHKEFLRLRRR--------QKRQNKEEDVTRESRFNFSGYGMGHCLQVKD 385
Query: 422 RMMVQLTLASERSSPQRKSQ--RSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
V+ T A+ P + + +V ID SR FP A+++FN+ YW
Sbjct: 386 GTAVKATPANPLPQPPKDGDAIKKKFVDR---AKRIDTISRAAFPLAFLIFNIFYW 438
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 273 bits (698), Expect = 3e-73
Identities = 151/421 (35%), Positives = 244/421 (57%), Gaps = 17/421 (4%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 30 RSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVN 89
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 90 IFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRIS 149
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W++ +++ +
Sbjct: 150 RNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVAD 208
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QF+++E + +TG + + F L R + ++L+Q Y P+ L+V+LSW+
Sbjct: 209 GLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWI 268
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 269 SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 328
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYM-PENGEKP 420
YAAVN+++ Q ++ + R K R + +G N M P +
Sbjct: 329 YAAVNFVSR-QHKELLRFRRK----------RRHHKEDEAGEGRFNFSAYGMGPACLQAK 377
Query: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRI---DTHAIDKYSRIIFPAAYILFNLIYWSI 477
D + V+ S ++P +S ++ IDK SRI FP A+++FN+ YW I
Sbjct: 378 DGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWII 437
Query: 478 F 478
+
Sbjct: 438 Y 438
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 268 bits (684), Expect = 1e-71
Identities = 150/418 (35%), Positives = 239/418 (57%), Gaps = 18/418 (4%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 35 RSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 94
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 95 IFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIF 154
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W + ++ E
Sbjct: 155 KNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QDEAPVQVAE 213
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QFL++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 214 GLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV 273
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 274 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 333
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGE-VNDLDNYMPENGEKP 420
YAAVN+++ + + R++ + R + Y G + D P+ P
Sbjct: 334 YAAVNFVSRQHKELLRFRRKRKNKDDEVRESRFSFT--AYGMGPCLQAKDGMTPKGPNHP 391
Query: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIF 478
++M + SP R ++ ID SR FP A+++FN+ YW I+
Sbjct: 392 VQVMPK--------SPD--EMRKVFIDR---AKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 266 bits (680), Expect = 3e-71
Identities = 148/420 (35%), Positives = 235/420 (55%), Gaps = 7/420 (1%)
Query: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 35 RSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 94
Query: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 95 IFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIF 154
Query: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W + ++ E
Sbjct: 155 KNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QDEAPVQVAE 213
Query: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
++L QFL++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 214 GLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV 273
Query: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 274 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 333
Query: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421
YAAVN+++ + + R++ T + D EV + G P
Sbjct: 334 YAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSD--MDDEVRESRFSFTAYGMGPC 391
Query: 422 RMMVQLTLASERSSPQRKSQRSSYVSMRI---DTHAIDKYSRIIFPAAYILFNLIYWSIF 478
+ P + +S ++ ID SR FP A+++FN+ YW I+
Sbjct: 392 LQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 262 bits (669), Expect = 6e-70
Identities = 152/416 (36%), Positives = 233/416 (56%), Gaps = 16/416 (3%)
Query: 64 SPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLY 123
+P I + +T+ L + +D +RP G + DV V S+ + ++M++T+ +
Sbjct: 56 APKIHEGDITQILNSL-LQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII 114
Query: 124 LRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPD 183
W D RL F ST + M + +V KIW+PD FF +S++S H TT N +LR+ D
Sbjct: 115 FAQTWFDSRLKFNSTMKVLM-LNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWND 173
Query: 184 GKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERI 243
G+VLY+LR+T+ A C + FP+D +C LE SY Y ++++ WKK + + +
Sbjct: 174 GRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
Query: 244 SLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSF 303
L QF +T++ ++ +G Y + I F L R + +F +QTY P L V+LSWVSF
Sbjct: 234 RLYQFAFVGLRNSTEIT-HTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSF 292
Query: 304 WIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYA 363
WI++ AVPAR LGITTVLTM+T+ T S+P+VSY+ A+D+++ V F+FVF +++EY
Sbjct: 293 WINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYG 352
Query: 364 AVNYLTTVQE----RKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEK 419
++Y T+ Q+ K++KL+ K T GL P T + N S V D+Y + E
Sbjct: 353 TLHYFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNIS---VPQEDDYGYQCLEG 409
Query: 420 PDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
D R+ R+ + + I ID YSRI FP A+ LFNL+YW
Sbjct: 410 KDCASFFCCFEDCRTGSWREGR------IHIRIAKIDSYSRIFFPTAFALFNLVYW 459
>gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precursor
[Homo sapiens]
Length = 632
Score = 262 bits (669), Expect = 6e-70
Identities = 124/324 (38%), Positives = 202/324 (62%), Gaps = 2/324 (0%)
Query: 84 HDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSM 143
+D +RP FGG +PV + + V S++ ISE++MD+T+T++ WKD RL++ T L++
Sbjct: 70 YDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETT-LNL 128
Query: 144 TFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFS 203
T D R+ +K+WVPD +F++SK +F+HD T +N + ++ PDG V Y +R+T TA C++D
Sbjct: 129 TLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLH 188
Query: 204 RFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYS 263
+FP+D Q C+L +ESY YT +D++L+W +++ E + + QF T T Y
Sbjct: 189 KFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLG-RTITSKEVYF 247
Query: 264 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT 323
TG Y RL + F ++R + +L+Q Y+P L + SW+SFW++ + ARV +G+T++L
Sbjct: 248 YTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLI 307
Query: 324 MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKL 383
++TI + + +P +S IKA+DIY+ V FVFLS+LEY +NYL + + Q R +
Sbjct: 308 LTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRR 367
Query: 384 PCTSGLPPPRTAMLDGNYSDGEVN 407
P ++ GN DG +N
Sbjct: 368 PRRVIARYRYQQVVVGNVQDGLIN 391
Score = 35.8 bits (81), Expect = 0.088
Identities = 12/21 (57%), Positives = 18/21 (85%)
Query: 455 IDKYSRIIFPAAYILFNLIYW 475
+DK+SR +FP A+ LFN++YW
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYW 627
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 253 bits (646), Expect = 3e-67
Identities = 121/303 (39%), Positives = 197/303 (65%), Gaps = 1/303 (0%)
Query: 80 RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTN 139
R +D +RP F GP + V ++ + S SI++ MD+ + ++LR W D RLS+
Sbjct: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYP 113
Query: 140 NLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCN 199
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+ +G VLYS+R+T+ C
Sbjct: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCL 173
Query: 200 MDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKL 259
MD FP+D QTC++++ES+ YT DL+ W + +++ E ++L QF++++
Sbjct: 174 MDLKNFPMDIQTCTMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCC 233
Query: 260 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGIT 319
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV LGIT
Sbjct: 234 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGIT 293
Query: 320 TVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKL 379
TVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LEYAA+N+++ Q ++ +L
Sbjct: 294 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSR-QHKEFIRL 352
Query: 380 REK 382
R +
Sbjct: 353 RRR 355
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 252 bits (643), Expect = 6e-67
Identities = 137/396 (34%), Positives = 225/396 (56%), Gaps = 9/396 (2%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
++ +D +RP G + D+ V S+ ++ ++M++T+ ++ W D RL F ST
Sbjct: 74 LEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIK 133
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + + +V KIW+PD FF +SK++ H TT N MLR+ DG+VLY+LR+T+ A C +
Sbjct: 134 V-LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQL 192
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLA 260
FP+D +C LE SY Y ++++ WK+ + + L QF TT++
Sbjct: 193 QLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 261 FYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITT 320
+++G Y + + F L R + +F +QTY P TL+V+LSWVSFWI++ AVPAR LGITT
Sbjct: 253 -KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 321 VLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE-RKEQKL 379
VLTM+T+ T S+P+VSY+ A+D+++ V F+FVF +++EY ++Y + ++ K++
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDK 371
Query: 380 REKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRK 439
++K P + PR+A + N + + Y E + D R+ R
Sbjct: 372 KKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRH 431
Query: 440 SQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
+ + I +D Y+RI FP A+ LFNL+YW
Sbjct: 432 GR------IHIRIAKMDSYARIFFPTAFCLFNLVYW 461
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 251 bits (640), Expect = 1e-66
Identities = 152/455 (33%), Positives = 238/455 (52%), Gaps = 31/455 (6%)
Query: 41 RPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVG 100
R ++ + +ED+ +L T L ++ LLR ++D +RP G +
Sbjct: 18 RSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNK-LLR--EYDKKLRPDIGIKPTVID 74
Query: 101 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFF 160
VD+ V S+ +S ++M++ + ++ W D RL F ST + +T + +V IW+PD F
Sbjct: 75 VDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKI-LTLNSNMVGLIWIPDTIF 133
Query: 161 VHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYA 220
+SK + H TT N +LR+ DGK+LY+LR+T+ A C + FP+D +C L SY
Sbjct: 134 RNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYG 193
Query: 221 YTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRH 280
Y +++++ W+K + + L QF TT++ +S G Y + I F L R
Sbjct: 194 YPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVT-TSAGDYVVMTIYFELSRR 252
Query: 281 IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSY 340
+ +F +QTY P L V+LSWVSFWI + A PAR LGITTVLTM+T+ T S+PRVSY
Sbjct: 253 MGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSY 312
Query: 341 IKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKL--PCTS----------- 387
+ A+D+++ V F+FVF +++EYA +NY ++ ++ K L P +S
Sbjct: 313 VTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQA 372
Query: 388 -------GLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKS 440
+ PP TAM+ N S D + E + D +S RK
Sbjct: 373 PSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKG 432
Query: 441 QRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
+ + ID +D YSR+ FP +++LFNL+YW
Sbjct: 433 R------IHIDILELDSYSRVFFPTSFLLFNLVYW 461
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 250 bits (638), Expect = 2e-66
Identities = 144/413 (34%), Positives = 226/413 (54%), Gaps = 27/413 (6%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
++ +D +RPGFGG V D+ V S +S+V+M++TM ++ R W DERL F
Sbjct: 40 LEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTE 99
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ ++ + +V KIW PD FF + K+S H+ TT N + R+ +G +LY++R+T+ A C M
Sbjct: 100 I-LSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPM 158
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGN--DSLKTDERISLSQF-LIQEFHTTT 257
FP+D C L+ SYAY + +++ WKKG +E SL Q+ LI + T +
Sbjct: 159 RLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQ--TVS 216
Query: 258 KLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLG 317
S+TG Y + + F L+R + +F++Q Y P + V+LS VSFWI++ +VPAR G
Sbjct: 217 SETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFG 276
Query: 318 ITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQ 377
ITTVLTM+T+ S+P+VSY A+D ++ V F FVF +++E+AAVNY T +Q +K +
Sbjct: 277 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAK 336
Query: 378 KLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQ 437
+ + PP T + E+ P++ + + L+L SS
Sbjct: 337 RKAQ-----FAAPPTVTISKATEPLEAEI----VLHPDSKYHLKKRITSLSLPIVSSSEA 387
Query: 438 RKSQRSSYVSMRI------------DTHAIDKYSRIIFPAAYILFNLIYWSIF 478
K + + T ID+YSRI+FP A+ FNL+YW ++
Sbjct: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 248 bits (633), Expect = 9e-66
Identities = 139/404 (34%), Positives = 225/404 (55%), Gaps = 17/404 (4%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
++ +D +RP G + D+ V S+ ++ ++M++T+ ++ W D RL F ST
Sbjct: 74 LEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIK 133
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + + +V KIW+PD FF +SK++ H TT N MLR+ DG+VLY+LR+T+ A C +
Sbjct: 134 V-LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQL 192
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLA 260
FP+D +C LE SY Y ++++ WK+ + + L QF TT++
Sbjct: 193 QLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 261 FYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITT 320
+++G Y + + F L R + +F +QTY P TL+V+LSWVSFWI++ AVPAR LGITT
Sbjct: 253 -KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 321 VLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLR 380
VLTM+T+ T S+P+VSY+ A+D+++ V F+FVF +++EY ++Y + ++ + K +
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDK 371
Query: 381 EK----LPCTSGLPP-----PRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLAS 431
+K L S P PR+A + N + + Y E + D
Sbjct: 372 KKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFED 431
Query: 432 ERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
R+ R + + I +D Y+RI FP A+ LFNL+YW
Sbjct: 432 CRTGAWRHGR------IHIRIAKMDSYARIFFPTAFCLFNLVYW 469
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 246 bits (627), Expect = 4e-65
Identities = 161/488 (32%), Positives = 260/488 (53%), Gaps = 64/488 (13%)
Query: 37 SKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLR--IDDHDFSMRPGFGG 94
SKKG+ ++++ + P + + D+ + P + +L + +D +RP F G
Sbjct: 27 SKKGKGKKKQ---------YLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKG 77
Query: 95 PAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPST--NNLSMTFDGRLVKK 152
+ V V++ + S SI E MD+ + ++LR W D RL PS + ++T D + K
Sbjct: 78 IPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKC 137
Query: 153 IWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTC 212
+W PD+FF + K + HD T +N++L + DG VL S+R+++T C +D + FP+DTQ C
Sbjct: 138 LWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRC 197
Query: 213 SLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQ----EFHTTTKLAFYSSTGWY 268
+++ES+ YT DDL W+ G D ++ E+I+L QF I+ E+ TK +Y TG+Y
Sbjct: 198 KMQLESFGYTTDDLRFIWQSG-DPVQL-EKIALPQFDIKKEDIEYGNCTK--YYKGTGYY 253
Query: 269 NRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTII 328
+ + FTLRR + F+++ Y P L+V+LSW+SFWI+ A ARVPLGI +VL++++
Sbjct: 254 TCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASEC 313
Query: 329 TGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE-QKLR------- 380
T + A +P+VSY+KA+D++L +F F S++EYA V + +R E +K R
Sbjct: 314 TTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQA 373
Query: 381 -------EKLPCTSGLPPP-----------RTAMLDGNYSDGEVNDLD--NYMPENGE-- 418
K +G P R + + SD ND +P + E
Sbjct: 374 DGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELS 433
Query: 419 ------KPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHA--IDKYSRIIFPAAYILF 470
KP + V L ++ +K + V I T A ID Y+R +FP ++ F
Sbjct: 434 NYDCYGKP--IEVNNGLGKSQAKNNKKPPPAKPV---IPTAAKRIDLYARALFPFCFLFF 488
Query: 471 NLIYWSIF 478
N+IYWSI+
Sbjct: 489 NVIYWSIY 496
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 241 bits (616), Expect = 8e-64
Identities = 144/428 (33%), Positives = 233/428 (54%), Gaps = 20/428 (4%)
Query: 65 PDITKSPLTKSEQLLR--IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTL 122
PD + +T ++L +D +D +RPG G V D+ V S +S+ DM++T+ +
Sbjct: 57 PDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDV 116
Query: 123 YLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQP 182
+ R W DERL F + + + L KIW PD FF + K+S H+ TT N +LR+
Sbjct: 117 FFRQTWHDERLKFDGPMKI-LPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVD 175
Query: 183 DGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKG-NDSLKTDE 241
+G +LY++R+T+ A C M FP+D C L+ SYAYT +++ W G N S++ +
Sbjct: 176 NGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQ 235
Query: 242 RIS-LSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW 300
S L+Q+ + T++ SSTG Y + +F L+R I +F++QTY P + V+LS
Sbjct: 236 DGSRLNQYDLLGHVVGTEI-IRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 294
Query: 301 VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL 360
VSFW++R +VPAR G+TTVLTM+T+ S+P+V+Y A+D ++ V + FVF +++
Sbjct: 295 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 354
Query: 361 EYAAVNYLT----TVQERKEQKLREKLPCTSGLPPPRTA----MLDGNYSDGEVNDLDNY 412
E+A VNY T + +K + E T P +T+ ++ Y D +
Sbjct: 355 EFATVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFS 414
Query: 413 MPENGEKPDRMMVQLTLASERSSPQRKS--QRSSYVSMRIDTHAIDKYSRIIFPAAYILF 470
G P +AS +++ + S + +Y S+ +DK SRIIFP + +F
Sbjct: 415 TISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSV----SKVDKISRIIFPVLFAIF 470
Query: 471 NLIYWSIF 478
NL+YW+ +
Sbjct: 471 NLVYWATY 478
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 241 bits (614), Expect = 1e-63
Identities = 137/414 (33%), Positives = 221/414 (53%), Gaps = 39/414 (9%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
+D +D +RPG G V ++ V S +S+ DM++T+ ++ R WKDERL F N
Sbjct: 50 LDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMN 109
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + + + KIW PD FF + K+S H+ T N +LR+Q DG +LY++R+TV A C M
Sbjct: 110 I-LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPM 168
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWK-KGNDSLKT---DERISLSQFLIQEFHTT 256
FP+D +C L+ SYAYT ++ W +DS++ R++ L Q
Sbjct: 169 HLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKE 228
Query: 257 TKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPL 316
T SSTG Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR
Sbjct: 229 T---IKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVF 285
Query: 317 GITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT------- 369
G+TTVLTM+T+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T
Sbjct: 286 GVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWD 345
Query: 370 ---TVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQ 426
V ++K++K + M+ N + NY P + P ++
Sbjct: 346 GKSVVNDKKKEK--------------ASVMIQNN---AYAVAVANYAPNLSKDP--VLST 386
Query: 427 LTLASERSSPQRKSQRSSYVSMRI--DTHAIDKYSRIIFPAAYILFNLIYWSIF 478
++ ++ P +K + + + ID+ SRI+FP + FNL+YW+ +
Sbjct: 387 ISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 241 bits (614), Expect = 1e-63
Identities = 137/414 (33%), Positives = 221/414 (53%), Gaps = 39/414 (9%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
+D +D +RPG G V ++ V S +S+ DM++T+ ++ R WKDERL F N
Sbjct: 50 LDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMN 109
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + + + KIW PD FF + K+S H+ T N +LR+Q DG +LY++R+TV A C M
Sbjct: 110 I-LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPM 168
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWK-KGNDSLKT---DERISLSQFLIQEFHTT 256
FP+D +C L+ SYAYT ++ W +DS++ R++ L Q
Sbjct: 169 HLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKE 228
Query: 257 TKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPL 316
T SSTG Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR
Sbjct: 229 T---IKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVF 285
Query: 317 GITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT------- 369
G+TTVLTM+T+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T
Sbjct: 286 GVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWD 345
Query: 370 ---TVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQ 426
V ++K++K + M+ N + NY P + P ++
Sbjct: 346 GKSVVNDKKKEK--------------ASVMIQNN---AYAVAVANYAPNLSKDP--VLST 386
Query: 427 LTLASERSSPQRKSQRSSYVSMRI--DTHAIDKYSRIIFPAAYILFNLIYWSIF 478
++ ++ P +K + + + ID+ SRI+FP + FNL+YW+ +
Sbjct: 387 ISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 237 bits (604), Expect = 2e-62
Identities = 135/412 (32%), Positives = 221/412 (53%), Gaps = 34/412 (8%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
+D +D +RPG G V D+ V S +S+ +M++T+ ++ R WKDERL F
Sbjct: 57 LDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQ 116
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + L KIW PD FF + K+S H+ TT N +LR++ DG +LY++R+T++A C M
Sbjct: 117 -RLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPM 175
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDS--LKTDERISLSQFLIQEFHTTTK 258
FP+D C L+ SYAY +++ W G+ + ++ L+Q+ + T+
Sbjct: 176 QLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTE 235
Query: 259 LAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGI 318
+STG Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR G+
Sbjct: 236 -NISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGV 294
Query: 319 TTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT--------- 369
TTVLTM+T+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T
Sbjct: 295 TTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGK 354
Query: 370 -TVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPEN--GEKPDRMMVQ 426
++ K +K RE + S ++ G+++ N E + V
Sbjct: 355 KALEAAKIKKKREVILNKS----------TNAFTTGKMSHPPNIPKEQTPAGTSNTTSVS 404
Query: 427 LTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIF 478
+ + E++S +K+ S IDK SRI+FP + FNL+YW+ +
Sbjct: 405 VKPSEEKTSESKKTYNS--------ISKIDKMSRIVFPVLFGTFNLVYWATY 448
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 233 bits (593), Expect = 4e-61
Identities = 119/307 (38%), Positives = 184/307 (59%), Gaps = 6/307 (1%)
Query: 81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNN 140
+D +D +RPGFGGP V D+ V S +S+V+M++TM ++ R W D+RL +
Sbjct: 56 LDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIE 115
Query: 141 LSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNM 200
+ + + +V K+W PD FF + K+S H+ T N + R+ +G +LY++R+T++A C M
Sbjct: 116 I-LRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPM 174
Query: 201 DFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEF---HTTT 257
FP+D C L+ SYAY + +++ W KG + K+ E S L+Q T +
Sbjct: 175 RLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPE--KSVEVPKESSSLVQYDLIGQTVS 232
Query: 258 KLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLG 317
S TG Y + + F LRR + +F++QTY P + V+LS VSFWI++ +VPAR G
Sbjct: 233 SETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFG 292
Query: 318 ITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQ 377
ITTVLTM+T+ S+P+VSY A+D ++ V F FVF +++E+AAVNY T +Q K +
Sbjct: 293 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMEKAK 352
Query: 378 KLREKLP 384
+ K P
Sbjct: 353 RKTSKPP 359
Score = 38.1 bits (87), Expect = 0.018
Identities = 13/27 (48%), Positives = 20/27 (74%)
Query: 452 THAIDKYSRIIFPAAYILFNLIYWSIF 478
T IDKY+RI+FP + FN++YW ++
Sbjct: 515 TSKIDKYARILFPVTFGAFNMVYWVVY 541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,618,590
Number of Sequences: 37866
Number of extensions: 764660
Number of successful extensions: 2744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2561
Number of HSP's gapped (non-prelim): 97
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.