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Search of human proteins with 18201888
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo
sapiens]
(382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 776 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 490 e-138
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 490 e-138
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 490 e-138
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 480 e-136
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 451 e-127
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 451 e-127
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 439 e-123
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 236 3e-62
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 236 3e-62
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 110 3e-24
gi|38201714 ELAV-like 1 [Homo sapiens] 108 8e-24
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 107 1e-23
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 104 1e-22
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 103 3e-22
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 99 5e-21
gi|55956788 nucleolin [Homo sapiens] 94 3e-19
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 90 3e-18
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 88 1e-17
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 87 2e-17
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 87 2e-17
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 87 2e-17
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 87 2e-17
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 85 1e-16
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 85 1e-16
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 85 1e-16
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 83 4e-16
gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b... 83 5e-16
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 82 8e-16
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 82 8e-16
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 776 bits (2003), Expect = 0.0
Identities = 382/382 (100%), Positives = 382/382 (100%)
Query: 1 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG 60
MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
Sbjct: 1 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG 60
Query: 61 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 120
YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
Sbjct: 61 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 120
Query: 121 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF 180
ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
Sbjct: 121 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF 180
Query: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG 240
KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
Sbjct: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG 240
Query: 241 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP 300
FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
Sbjct: 241 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP 300
Query: 301 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE 360
GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
Sbjct: 301 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE 360
Query: 361 MNGRIVGSKPLHVTLGQARRRC 382
MNGRIVGSKPLHVTLGQARRRC
Sbjct: 361 MNGRIVGSKPLHVTLGQARRRC 382
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 490 bits (1261), Expect = e-138
Identities = 243/365 (66%), Positives = 300/365 (82%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL DVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 8 YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNFD+I GKP R+MWSQ D LRKSGVGN+FIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 68 ALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
CKVVCD+NGSKGYA+VHF++ AA++AI MNG+ LN+R+V+VGRFK +ER AE+ +
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
+ FTNV++KN G+++DDE LKELF ++G T SVKV+RD +GKSKGFGFV YE HE A K
Sbjct: 188 K-EFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV +++GK I GK+++VGRAQKK+ER AEL+R+FE+L+ + SR GV +YIKNLD+TI+
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
DEKL++EFS FGSI+ AKVM+E G+ KGFG VCFSS EEATKAV EMNGRIVGSKPL+V
Sbjct: 307 DEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 153 bits (386), Expect = 3e-37
Identities = 97/285 (34%), Positives = 155/285 (54%), Gaps = 19/285 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +LD + LY F G + ++ D GY +V+F A+ A+ M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+N K F + +R + G N++IKN + +D+ +L LFS FG L
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL 218
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D NG SKG+ +V ++ AN+A+ MNG ++ + ++VGR + ER AE++
Sbjct: 219 SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR 278
Query: 193 R---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
+ R N+++KN+ D IDDEKL++ F +G S KV+ + G+SKGFGF
Sbjct: 279 KFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGF 337
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQY 382
Score = 77.8 bits (190), Expect = 2e-14
Identities = 50/183 (27%), Positives = 98/183 (53%), Gaps = 19/183 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
++ I GK + + +Q+ R GV ++IKNLD++I+++
Sbjct: 72 MNFDVIKGKPIRIMWSQRD-----------------PSLRKSGVGNVFIKNLDKSIDNKA 114
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
L + FS+FG+I KV+ + KG+ V F + E A KA+++MNG ++ + + V +
Sbjct: 115 LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK 174
Query: 378 ARR 380
+R+
Sbjct: 175 SRK 177
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
+Y LY+ +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 290 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSK--GFGFVCFSSPEEAT 347
Query: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
A+ MN ++ KP + +Q + RK+ + N +++ +
Sbjct: 348 KAVTEMNGRIVGSKPLYVALAQRKEE-RKAHLTNQYMQRV 386
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 490 bits (1261), Expect = e-138
Identities = 243/365 (66%), Positives = 300/365 (82%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL DVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 8 YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNFD+I GKP R+MWSQ D LRKSGVGN+FIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 68 ALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
CKVVCD+NGSKGYA+VHF++ AA++AI MNG+ LN+R+V+VGRFK +ER AE+ +
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
+ FTNV++KN G+++DDE LKELF ++G T SVKV+RD +GKSKGFGFV YE HE A K
Sbjct: 188 K-EFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV +++GK I GK+++VGRAQKK+ER AEL+R+FE+L+ + SR GV +YIKNLD+TI+
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
DEKL++EFS FGSI+ AKVM+E G+ KGFG VCFSS EEATKAV EMNGRIVGSKPL+V
Sbjct: 307 DEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 153 bits (386), Expect = 3e-37
Identities = 97/285 (34%), Positives = 155/285 (54%), Gaps = 19/285 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +LD + LY F G + ++ D GY +V+F A+ A+ M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+N K F + +R + G N++IKN + +D+ +L LFS FG L
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL 218
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D NG SKG+ +V ++ AN+A+ MNG ++ + ++VGR + ER AE++
Sbjct: 219 SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR 278
Query: 193 R---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
+ R N+++KN+ D IDDEKL++ F +G S KV+ + G+SKGFGF
Sbjct: 279 KFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGF 337
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQY 382
Score = 77.8 bits (190), Expect = 2e-14
Identities = 50/183 (27%), Positives = 98/183 (53%), Gaps = 19/183 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
++ I GK + + +Q+ R GV ++IKNLD++I+++
Sbjct: 72 MNFDVIKGKPIRIMWSQRD-----------------PSLRKSGVGNVFIKNLDKSIDNKA 114
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
L + FS+FG+I KV+ + KG+ V F + E A KA+++MNG ++ + + V +
Sbjct: 115 LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK 174
Query: 378 ARR 380
+R+
Sbjct: 175 SRK 177
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
+Y LY+ +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 290 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSK--GFGFVCFSSPEEAT 347
Query: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
A+ MN ++ KP + +Q + RK+ + N +++ +
Sbjct: 348 KAVTEMNGRIVGSKPLYVALAQRKEE-RKAHLTNQYMQRV 386
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 490 bits (1261), Expect = e-138
Identities = 243/365 (66%), Positives = 300/365 (82%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL DVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 8 YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNFD+I GKP R+MWSQ D LRKSGVGN+FIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 68 ALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
CKVVCD+NGSKGYA+VHF++ AA++AI MNG+ LN+R+V+VGRFK +ER AE+ +
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
+ FTNV++KN G+++DDE LKELF ++G T SVKV+RD +GKSKGFGFV YE HE A K
Sbjct: 188 K-EFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV +++GK I GK+++VGRAQKK+ER AEL+R+FE+L+ + SR GV +YIKNLD+TI+
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
DEKL++EFS FGSI+ AKVM+E G+ KGFG VCFSS EEATKAV EMNGRIVGSKPL+V
Sbjct: 307 DEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 153 bits (386), Expect = 3e-37
Identities = 97/285 (34%), Positives = 155/285 (54%), Gaps = 19/285 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +LD + LY F G + ++ D GY +V+F A+ A+ M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+N K F + +R + G N++IKN + +D+ +L LFS FG L
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL 218
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D NG SKG+ +V ++ AN+A+ MNG ++ + ++VGR + ER AE++
Sbjct: 219 SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR 278
Query: 193 R---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
+ R N+++KN+ D IDDEKL++ F +G S KV+ + G+SKGFGF
Sbjct: 279 KFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGF 337
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQY 382
Score = 77.8 bits (190), Expect = 2e-14
Identities = 50/183 (27%), Positives = 98/183 (53%), Gaps = 19/183 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
++ I GK + + +Q+ R GV ++IKNLD++I+++
Sbjct: 72 MNFDVIKGKPIRIMWSQRD-----------------PSLRKSGVGNVFIKNLDKSIDNKA 114
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
L + FS+FG+I KV+ + KG+ V F + E A KA+++MNG ++ + + V +
Sbjct: 115 LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK 174
Query: 378 ARR 380
+R+
Sbjct: 175 SRK 177
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
+Y LY+ +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 290 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSK--GFGFVCFSSPEEAT 347
Query: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
A+ MN ++ KP + +Q + RK+ + N +++ +
Sbjct: 348 KAVTEMNGRIVGSKPLYVALAQRKEE-RKAHLTNQYMQRV 386
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 480 bits (1236), Expect = e-136
Identities = 238/365 (65%), Positives = 296/365 (81%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL PDVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 8 YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNFD+I GKP R+MWSQ D LRKSGVGNIFIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 68 ALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
CKVVCD+NGSKGY +VHF++ AA RAI MNG+ LN+R+V+VGRFK +ER AE+ R
Sbjct: 128 CKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARA 187
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
+ FTNV++KN G+D+DDE+LK+LF ++GP SVKV+ D SGKSKGFGFV +E HE AQK
Sbjct: 188 K-EFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV +++GK ++GK +YVGRAQKK+ER EL+R+FE+++ +R GV +Y+KNLD+ I+
Sbjct: 247 AVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
DE+L++EFS FG+I+ AKVMME G+ KGFG VCFSS EEATKAV EMNGRIV +KPL+V
Sbjct: 307 DERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 155 bits (393), Expect = 4e-38
Identities = 102/285 (35%), Positives = 156/285 (54%), Gaps = 19/285 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +LD + LY F G + ++ D GYG+V+F AE A+ M
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKM 158
Query: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+N K F + +R + G N++IKN + +D+ L LF FG L
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPAL 218
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D++G SKG+ +V F+ A +A+ MNG LN +Q+YVGR + ER E++
Sbjct: 219 SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKR 278
Query: 193 R------DRATF---TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
+ DR T N++VKN+ D IDDE+L++ F +G S KV+ + G+SKGFGF
Sbjct: 279 KFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGF 337
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQY 382
Score = 78.2 bits (191), Expect = 1e-14
Identities = 51/183 (27%), Positives = 99/183 (54%), Gaps = 19/183 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
++ I GK + + +Q+ R GV I+IKNLD++I+++
Sbjct: 72 MNFDVIKGKPVRIMWSQRD-----------------PSLRKSGVGNIFIKNLDKSIDNKA 114
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
L + FS+FG+I KV+ + KG+G V F + E A +A+++MNG ++ + + V +
Sbjct: 115 LYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK 174
Query: 378 ARR 380
+R+
Sbjct: 175 SRK 177
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
+Y LYV +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 290 RYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSK--GFGFVCFSSPEEAT 347
Query: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
A+ MN ++ KP + +Q + R++ + N +++ +
Sbjct: 348 KAVTEMNGRIVATKPLYVALAQRKEE-RQAHLTNQYMQRM 386
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 451 bits (1161), Expect = e-127
Identities = 226/365 (61%), Positives = 284/365 (77%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL PDVTE MLY+KF PAGP+ RICRD +T Y YVNF+ DAE
Sbjct: 8 YPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEH 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNFD+I GKP R+MWSQ D LRKSGVGNIF+KNLDKSI+N+AL+ SAFGNILS
Sbjct: 68 ALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
C VVCD+NGSKGY +VHF++ AA RAI MNG+ LN R+V+VG+FK +ER AE+ R
Sbjct: 128 CNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARA 187
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
+ F NV++KN G+D+DDE+LK+LF ++GP SVKV+ D SGKSKGFGFV +E HE AQK
Sbjct: 188 K-EFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV +++GK ++GK +YVGRAQKK+ER EL+R FE+++ +R V +Y+KNLD+ I+
Sbjct: 247 AVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
DE+L++ FS FG+I+ AKVMME G+ KGFG VCFSS EEATKAV EMNGRIV +KPL+V
Sbjct: 307 DERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 157 bits (398), Expect = 1e-38
Identities = 109/315 (34%), Positives = 165/315 (52%), Gaps = 23/315 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +LD + LY G + + D GYG+V+F AE A+ M
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKKM 158
Query: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+NG K F + +R + G N++IKN + +D+ L LF FG L
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPAL 218
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D++G SKG+ +V F+ A +A+ MNG LN +Q+YVGR + ER E++
Sbjct: 219 SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKR 278
Query: 193 ------RDRAT---FTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
+DR T N++VKN+ D IDDE+L++ F +G S KV+ + G+SKGFGF
Sbjct: 279 TFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG-GRSKGFGF 337
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLA----ELRRRFERLRLKEKSRP 299
V + + E A KAV +++G+ + K LYV AQ+K ER A E +R +R R
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRA 397
Query: 300 PGVPIYIKNLDETIN 314
P ++ + +T N
Sbjct: 398 PPSGYFMTAVPQTQN 412
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/183 (25%), Positives = 94/183 (51%), Gaps = 19/183 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S+++ RD + S + +V ++ + A+ A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
++ I GK + + +Q+ R GV I++KNLD++IN++
Sbjct: 72 MNFDVIKGKPVRIMWSQRD-----------------PSLRKSGVGNIFVKNLDKSINNKA 114
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
L + S+FG+I V+ + KG+G V F + E A +A+ +MNG ++ + + V +
Sbjct: 115 LYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFK 174
Query: 378 ARR 380
+R+
Sbjct: 175 SRK 177
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
+Y LYV +LD + ++ L K F P G + ++ + G+G+V F P +A
Sbjct: 290 RYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSK--GFGFVCFSSPEEAT 347
Query: 74 WALNTMNFDLINGKPFRLMWSQ 95
A+ MN ++ KP + +Q
Sbjct: 348 KAVTEMNGRIVATKPLYVALAQ 369
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 451 bits (1159), Expect = e-127
Identities = 225/364 (61%), Positives = 289/364 (79%), Gaps = 1/364 (0%)
Query: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
KY A+LYVGDL DVTED+L++KF GP+ RICRD VTR LGY YVNF ADA+
Sbjct: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
Query: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNIL 133
AL+TMNFD+I GK RLMWSQ D LR+SG+GN+FIKNLDKSIDN+ L+ FSAFG IL
Sbjct: 66 KALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKIL 125
Query: 134 SCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTR 193
S KV+ DD GSKGYA+VHF + +AA+RAI MNG L +V+VGRFK ++R AE+R++
Sbjct: 126 SSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSK 185
Query: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQ 253
+ FTNV++KN G D+DDE+LK++F +YG T SVKV+ D+SGKSKGFGFV +++HEAA+
Sbjct: 186 -ASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
Query: 254 KAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETI 313
KAV +++G+ I+G++++VGRAQKK+ER AEL++ FE+L+ + GV +YIKNLD+TI
Sbjct: 245 KAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTI 304
Query: 314 NDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
+DEKL+ EFSSFGSISR KVM E GQ KGFG++CFSS E+ATKA+ EMNGRI+GSKPL +
Sbjct: 305 DDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
Query: 374 TLGQ 377
L Q
Sbjct: 365 ALAQ 368
Score = 144 bits (364), Expect = 1e-34
Identities = 97/283 (34%), Positives = 154/283 (54%), Gaps = 23/283 (8%)
Query: 102 KSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAAN 159
K + ++++ +L + LF FS G +LS ++ D S GYAYV+F LA A
Sbjct: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
Query: 160 RAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELF 219
+A+ MN + + + + +R A +R R+ NVF+KN+ ID++ L E F
Sbjct: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYLR---RSGIGNVFIKNLDKSIDNKTLYEHF 118
Query: 220 CEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIE 279
+G S KV+ D G SKG+ FV ++ AA +A+ +++GK + G ++VGR + + +
Sbjct: 119 SAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177
Query: 280 RLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-G 338
R AELR + +YIKN ++DE+LK+ FS +G KVM + G
Sbjct: 178 REAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSG 227
Query: 339 QGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRR 381
+ KGFG V F S E A KAV+EMNGR + + + V G+A+++
Sbjct: 228 KSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV--GRAQKK 268
Score = 138 bits (348), Expect = 7e-33
Identities = 89/273 (32%), Positives = 150/273 (54%), Gaps = 19/273 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +LD + LY+ F G + +++ D + GY +V+F+ + A+ A+ M
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEM 157
Query: 80 NFDLING-KPFRLMWSQPDDR-----LRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNIL 133
N L+ G K F + DR + S N++IKN +D+ L +FS +G L
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTL 217
Query: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
S KV+ D +G SKG+ +V FDS AA +A+ MNG +N + ++VGR + ER AE++
Sbjct: 218 SVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQ 277
Query: 193 ------RDR---ATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
R+R +++KN+ D IDDEKL+ F +G VKV+++ G+SKGFG
Sbjct: 278 MFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE-EGQSKGFGL 336
Query: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQK 276
+ + + E A KA+ +++G+ + K L + AQ+
Sbjct: 337 ICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 439 bits (1129), Expect = e-123
Identities = 216/365 (59%), Positives = 282/365 (77%), Gaps = 1/365 (0%)
Query: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Y A+LYVGDL PDVTE MLY+KF PAGP+ R+CRD TR LGY Y+NF+ PADAE
Sbjct: 8 YPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAER 67
Query: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
AL+TMNF+++ G+P R+MWSQ D LRKSGVGNIFIKNL+ SIDN+AL+ FS FGNILS
Sbjct: 68 ALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILS 127
Query: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
CKV CD++GS+G+ +VHF++ AA +AI MNG+ LN+R+V+VG FK ER AE+ R
Sbjct: 128 CKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGAR- 186
Query: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
FTN++VKN+ D+D++ L++LF ++G SVKV+RD SG S+ FGFV +E HE AQK
Sbjct: 187 ALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQK 246
Query: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
AV+ ++GK + G++LY GRAQK++ER EL+RRFE+++ R GV +Y+KNLD++I+
Sbjct: 247 AVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSID 306
Query: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
D+KL++EFS +G I+ AKVM E G KGFG VCFSS EEATKAV EMNGRIVG+KPL+V
Sbjct: 307 DDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVA 366
Query: 375 LGQAR 379
L Q +
Sbjct: 367 LAQRK 371
Score = 151 bits (381), Expect = 1e-36
Identities = 98/286 (34%), Positives = 157/286 (54%), Gaps = 21/286 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+++ +L+ + LY F G + ++ D G+G+V+F A+ A+NTM
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINTM 158
Query: 80 NFDLINGKPFRLMWSQPDDRLRKSGVG-------NIFIKNLDKSIDNRALFYLFSAFGNI 132
N L+N + + R R++ +G NI++KNL +D + L LFS FG +
Sbjct: 159 NGMLLNDRKV-FVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
Query: 133 LSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVR 191
LS KV+ D++G S+ + +V+F+ A +A+ HMNG ++ R +Y GR + ER E++
Sbjct: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELK 277
Query: 192 TR---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
R R N++VKN+ D IDD+KL++ F YG S KV+ + G SKGFG
Sbjct: 278 RRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG-GHSKGFG 336
Query: 243 FVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
FV + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 337 FVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQY 382
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/188 (26%), Positives = 98/188 (52%), Gaps = 29/188 (15%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ D+ + L E F GP S++V RD A+ +S G+ ++ ++ A++A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP------IYIKNLDET 312
++ + + G + +R+ R PG+ I+IKNL+++
Sbjct: 72 MNFEMLKG----------------------QPIRIMWSQRDPGLRKSGVGNIFIKNLEDS 109
Query: 313 INDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLH 372
I+++ L + FS+FG+I KV + +GFG V F + E A +A++ MNG ++ + +
Sbjct: 110 IDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVF 169
Query: 373 VTLGQARR 380
V ++RR
Sbjct: 170 VGHFKSRR 177
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
Query: 13 KKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADA 72
++Y LYV +LD + +D L K+F P G + ++ + G+G+V F P +A
Sbjct: 289 RRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEA 346
Query: 73 EWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
A+ MN ++ KP + +Q + RK+ + N +++ L
Sbjct: 347 TKAVTEMNGRIVGTKPLYVALAQRKEE-RKAILTNQYMQRL 386
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 236 bits (602), Expect = 3e-62
Identities = 117/196 (59%), Positives = 147/196 (75%), Gaps = 1/196 (0%)
Query: 18 AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALN 77
A+LYVGDL P+VTE MLY+KF PAGP+ RICRD +TR LGY YVN++ P DA+ AL
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 78 TMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
T+NFD+I G+P R+MWSQ D LRKSGVGN+FIKNL K+IDN+AL+ +FSAFGNILSCKV
Sbjct: 62 TLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKV 121
Query: 138 VCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRAT 197
CD+ G KGY +VHF +A RAI MNG+ LN R+++VGRFK +ER AE R +
Sbjct: 122 ACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQS 181
Query: 198 FTNVFVKNIGDDIDDE 213
T+ VK+ +D D+E
Sbjct: 182 -TSADVKDFEEDTDEE 196
Score = 81.6 bits (200), Expect = 1e-15
Identities = 55/181 (30%), Positives = 96/181 (53%), Gaps = 10/181 (5%)
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAI 162
+ ++++ +L + L+ FS G ILS ++ D S GYAYV++ A RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 163 WHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEY 222
+N + R V + +R +R ++ NVF+KN+G ID++ L +F +
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSLR---KSGVGNVFIKNLGKTIDNKALYNIFSAF 113
Query: 223 GPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLA 282
G S KV D G KG+GFV ++ E+A++A+ ++G ++ + ++VGR + ER A
Sbjct: 114 GNILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREA 172
Query: 283 E 283
E
Sbjct: 173 E 173
Score = 70.1 bits (170), Expect = 3e-12
Identities = 49/176 (27%), Positives = 89/176 (50%), Gaps = 19/176 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ ++ + L E F GP S+++ RD + +S G+ +V Y+ A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
L+ I G+ + + +Q+ R GV ++IKNL +TI+++
Sbjct: 63 LNFDVIKGRPVRIMWSQRD-----------------PSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
L FS+FG+I KV + KG+G V F E A +A+D MNG + + + V
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFV 161
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 236 bits (602), Expect = 3e-62
Identities = 117/196 (59%), Positives = 147/196 (75%), Gaps = 1/196 (0%)
Query: 18 AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALN 77
A+LYVGDL P+VTE MLY+KF PAGP+ RICRD +TR LGY YVN++ P DA+ AL
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 78 TMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
T+NFD+I G+P R+MWSQ D LRKSGVGN+FIKNL K+IDN+AL+ +FSAFGNILSCKV
Sbjct: 62 TLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKV 121
Query: 138 VCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRAT 197
CD+ G KGY +VHF +A RAI MNG+ LN R+++VGRFK +ER AE R +
Sbjct: 122 ACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQS 181
Query: 198 FTNVFVKNIGDDIDDE 213
T+ VK+ +D D+E
Sbjct: 182 -TSADVKDFEEDTDEE 196
Score = 81.6 bits (200), Expect = 1e-15
Identities = 55/181 (30%), Positives = 96/181 (53%), Gaps = 10/181 (5%)
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAI 162
+ ++++ +L + L+ FS G ILS ++ D S GYAYV++ A RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 163 WHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEY 222
+N + R V + +R +R ++ NVF+KN+G ID++ L +F +
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSLR---KSGVGNVFIKNLGKTIDNKALYNIFSAF 113
Query: 223 GPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLA 282
G S KV D G KG+GFV ++ E+A++A+ ++G ++ + ++VGR + ER A
Sbjct: 114 GNILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREA 172
Query: 283 E 283
E
Sbjct: 173 E 173
Score = 70.1 bits (170), Expect = 3e-12
Identities = 49/176 (27%), Positives = 89/176 (50%), Gaps = 19/176 (10%)
Query: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
+++V ++ ++ + L E F GP S+++ RD + +S G+ +V Y+ A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
L+ I G+ + + +Q+ R GV ++IKNL +TI+++
Sbjct: 63 LNFDVIKGRPVRIMWSQRD-----------------PSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
L FS+FG+I KV + KG+G V F E A +A+D MNG + + + V
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFV 161
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 110 bits (274), Expect = 3e-24
Identities = 69/175 (39%), Positives = 98/175 (56%), Gaps = 5/175 (2%)
Query: 18 AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALN 77
A +YVG LD V+E +L++ F AGP+ T + +D VT GYG+V F DA++A+
Sbjct: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
Query: 78 TMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
MN + GKP R+ + ++ G NIFI NLD ID + L+ FSAFG IL
Sbjct: 73 IMNMIKLYGKPIRVNKASAHNKNLDVG-ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPK 131
Query: 138 VC---DDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAE 189
+ D SKGYA+++F S A++ AI MNG L NR + V + F ++ E
Sbjct: 132 IMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGE 185
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/185 (26%), Positives = 94/185 (50%), Gaps = 21/185 (11%)
Query: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAA 252
+R V+V + + + + L ELF + GP + + +D +G+ +G+GFV + + E A
Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
Query: 253 QKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDET 312
A+ ++ + GK + V +A K+ G I+I NLD
Sbjct: 68 DYAIKIMNMIKLYGKPIRVNKASAH-----------------NKNLDVGANIFIGNLDPE 110
Query: 313 INDEKLKEEFSSFGSISRAKVMM---EVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSK 369
I+++ L + FS+FG I + +M + G KG+ + F+SF+ + A++ MNG+ + ++
Sbjct: 111 IDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNR 170
Query: 370 PLHVT 374
P+ V+
Sbjct: 171 PITVS 175
Score = 48.9 bits (115), Expect = 8e-06
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 9 AGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGP-LRFTRICRDPVTRSPLGYGYVNFR 67
A K + A +++G+LDP++ E +LY F G L+ +I RDP T + GY ++NF
Sbjct: 91 AHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFA 150
Query: 68 FPADAEWALNTMNFDLINGKPFRLMWSQPDD 98
++ A+ MN + +P + ++ D
Sbjct: 151 SFDASDAAIEAMNGQYLCNRPITVSYAFKKD 181
Score = 38.1 bits (87), Expect = 0.013
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEM 361
+Y+ LDE +++ L E F G + + + GQ +G+G V F S E+A A+ M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 362 NGRIVGSKPLHVTLGQARRR 381
N + KP+ V A +
Sbjct: 75 NMIKLYGKPIRVNKASAHNK 94
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 108 bits (270), Expect = 8e-24
Identities = 85/298 (28%), Positives = 136/298 (45%), Gaps = 48/298 (16%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
L V L ++T+D L F G + ++ RD V LGYG+VN+ DAE A+NT+
Sbjct: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
Query: 80 NFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVC 139
N + K ++ +++P + K N++I L +++ + + +FS FG I++ +V+
Sbjct: 82 NGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLV 139
Query: 140 DDNG--SKGYAYVHFDSLAAANRAIWHMNGVR----------------LNNRQVYV---- 177
D S+G A++ FD + A AI NG + N+ V +
Sbjct: 140 DQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQL 199
Query: 178 -----GRFKFPEERAAE--------VRTRDRATFTNV----------FVKNIGDDIDDEK 214
RF P A+ V + NV F+ N+G D D+
Sbjct: 200 YHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGI 259
Query: 215 LKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV 271
L ++F +G +VKVIRD + K KGFGFV +E A A+ L+G + K+L V
Sbjct: 260 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
Score = 87.4 bits (215), Expect = 2e-17
Identities = 74/310 (23%), Positives = 140/310 (45%), Gaps = 48/310 (15%)
Query: 104 GVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRA 161
G N+ + L +++ L LFS+ G + S K++ D S GY +V++ + A RA
Sbjct: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
Query: 162 IWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCE 221
I +NG+RL ++ + V + E + N+++ + + + ++++F
Sbjct: 78 INTLNGLRLQSKTIKVSYARPSSEVIKD---------ANLYISGLPRTMTQKDVEDMFSR 128
Query: 222 YGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDG-------KVLYVGR 273
+G + +V+ D +G S+G F+R++ A++A+ +G G K
Sbjct: 129 FGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPN 188
Query: 274 AQKKIERLAEL-----------------RRRFERLRLKEKSRPPGVP----------IYI 306
K + L++L R RF + + S GV I+I
Sbjct: 189 QNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Query: 307 KNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
NL + ++ L + F FG+++ KV+ + + KGFG V +++EEA A+ +NG
Sbjct: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
Query: 365 IVGSKPLHVT 374
+G K L V+
Sbjct: 309 RLGDKILQVS 318
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 107 bits (268), Expect = 1e-23
Identities = 69/264 (26%), Positives = 128/264 (48%), Gaps = 14/264 (5%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
+++ NL + + + LFS G SCK++ + + Y +V F A A+ MNG
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
Query: 168 VRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTES 227
++ ++V V P + +D + +VFV ++ +I E +K F +G
Sbjct: 71 RKILGKEVKVNWATTPSS-----QKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISD 125
Query: 228 VKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIER-LAELR 285
+V++D A+GKSKG+GFV + A+ A++ + G+ + G+ + A +K +
Sbjct: 126 ARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE 185
Query: 286 RRFERLRLKE---KSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKG 342
++LR ++ +S P +Y + + D+ +++ FS FG I +V E KG
Sbjct: 186 NNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KG 241
Query: 343 FGVVCFSSFEEATKAVDEMNGRIV 366
+ V FS+ E A A+ +NG +
Sbjct: 242 YSFVRFSTHESAAHAIVSVNGTTI 265
Score = 104 bits (260), Expect = 1e-22
Identities = 76/267 (28%), Positives = 125/267 (46%), Gaps = 24/267 (8%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
LYVG+L DVTE ++ + F GP + ++ + + P Y +V F DA AL M
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
Query: 80 NFDLINGKPFRLMWSQPDDRLRK--SGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
N I GK ++ W+ +K S ++F+ +L I + F+ FG I +V
Sbjct: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128
Query: 138 VCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKFPEERAAEVRTR 193
V D SKGY +V F + A AI HM G L RQ+ K P ++ +
Sbjct: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNT 188
Query: 194 DRATFTNV-----------FVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
+ F +V + I + D+ +++ F +G ++V + KG+
Sbjct: 189 KQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE-----KGYS 243
Query: 243 FVRYETHEAAQKAVLDLHGKSIDGKVL 269
FVR+ THE+A A++ ++G +I+G V+
Sbjct: 244 FVRFSTHESAAHAIVSVNGTTIEGHVV 270
Score = 68.6 bits (166), Expect = 9e-12
Identities = 45/173 (26%), Positives = 83/173 (47%), Gaps = 17/173 (9%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
++V N+ D+ + + +LF + GP +S K+I + + + FV + H A A+ ++
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
Query: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
G+ I GK + V A + + F +++ +L I E +K
Sbjct: 70 GRKILGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKS 115
Query: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
F+ FG IS A+V+ M G+ KG+G V F + +A A+ M G+ +G + +
Sbjct: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI 168
Score = 30.8 bits (68), Expect = 2.1
Identities = 18/84 (21%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+Y G + +T+ ++ + F P G + R+ + GY +V F A A+ ++
Sbjct: 207 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSV 260
Query: 80 NFDLINGKPFRLMWSQPDDRLRKS 103
N I G + W + + K+
Sbjct: 261 NGTTIEGHVVKCYWGKESPDMTKN 284
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 104 bits (260), Expect = 1e-22
Identities = 66/264 (25%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
+++ NL + + + LFS G +CK++ D G+ Y +V F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 168 VRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTES 227
++ ++V V P + +D + +VFV ++ +I E +K F +G
Sbjct: 69 RKIMGKEVKVNWATTPSS-----QKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISD 123
Query: 228 VKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKK----IERLA 282
+V++D A+GKSKG+GFV + A+ A+ + G+ + G+ + A +K
Sbjct: 124 ARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE 183
Query: 283 ELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKG 342
++ + +S P +Y + + ++ +++ FS FG I +V + KG
Sbjct: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KG 239
Query: 343 FGVVCFSSFEEATKAVDEMNGRIV 366
+ V F+S E A A+ +NG +
Sbjct: 240 YSFVRFNSHESAAHAIVSVNGTTI 263
Score = 97.4 bits (241), Expect = 2e-20
Identities = 74/267 (27%), Positives = 122/267 (45%), Gaps = 24/267 (8%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
LYVG+L DVTE ++ + F GP + ++ D P Y +V F A AL M
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66
Query: 80 NFDLINGKPFRLMWSQPDDRLRK--SGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
N I GK ++ W+ +K S ++F+ +L I + F+ FG I +V
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARV 126
Query: 138 VCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKFPEERAA----- 188
V D SKGY +V F + A AI M G L RQ+ K P ++
Sbjct: 127 VKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNT 186
Query: 189 ------EVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
EV + + V+ + + ++ +++ F +G ++V D KG+
Sbjct: 187 KQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KGYS 241
Query: 243 FVRYETHEAAQKAVLDLHGKSIDGKVL 269
FVR+ +HE+A A++ ++G +I+G V+
Sbjct: 242 FVRFNSHESAAHAIVSVNGTTIEGHVV 268
Score = 74.7 bits (182), Expect = 1e-13
Identities = 46/173 (26%), Positives = 85/173 (49%), Gaps = 17/173 (9%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
++V N+ D+ + + +LF + GP ++ K+I D +G + FV + H A A+ ++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
G+ I GK + V A + + F +++ +L I E +K
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKA 113
Query: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
F+ FG IS A+V+ M G+ KG+G V F + +A A+ +M G+ +G + +
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI 166
Score = 32.7 bits (73), Expect = 0.56
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+Y G + +TE ++ + F P G + R+ D GY +V F A A+ ++
Sbjct: 205 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 258
Query: 80 NFDLINGKPFRLMWSQ 95
N I G + W +
Sbjct: 259 NGTTIEGHVVKCYWGK 274
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 103 bits (256), Expect = 3e-22
Identities = 67/270 (24%), Positives = 125/270 (46%), Gaps = 15/270 (5%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
+++ NL + + + LFS G +CK++ D G+ Y +V F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 168 VRLNNRQVYVGRFKFPEERAAE------VRTRDRATFTNVFVKNIGDDIDDEKLKELFCE 221
++ ++V V P + + V T+ +VFV ++ +I E +K F
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
Query: 222 YGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKK--- 277
+G +V++D A+GKSKG+GFV + A+ A+ + G+ + G+ + A +K
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
Query: 278 -IERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME 336
++ + +S P +Y + + ++ +++ FS FG I +V +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
Query: 337 VGQGKGFGVVCFSSFEEATKAVDEMNGRIV 366
KG+ V F+S E A A+ +NG +
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
Score = 93.2 bits (230), Expect = 3e-19
Identities = 76/278 (27%), Positives = 123/278 (44%), Gaps = 35/278 (12%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
LYVG+L DVTE ++ + F GP + ++ D P Y +V F A AL M
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66
Query: 80 NFDLINGKPFRLMW-----SQPDDRLRKSGVG--------NIFIKNLDKSIDNRALFYLF 126
N I GK ++ W SQ D + V ++F+ +L I + F
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
Query: 127 SAFGNILSCKVVCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKF 182
+ FG I +VV D SKGY +V F + A AI M G L RQ+ K
Sbjct: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
Query: 183 PEERAA-----------EVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVI 231
P ++ EV + + V+ + + ++ +++ F +G ++V
Sbjct: 187 PAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVF 246
Query: 232 RDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVL 269
D KG+ FVR+ +HE+A A++ ++G +I+G V+
Sbjct: 247 PD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
Score = 71.6 bits (174), Expect = 1e-12
Identities = 45/173 (26%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
++V N+ D+ + + +LF + GP ++ K+I D +G + FV + H A A+ ++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
G+ I GK + V A + + + + +++ +L I E +K
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTS---SSTVVSTQRSQDHFHVFVGDLSPEITTEDIKA 124
Query: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
F+ FG IS A+V+ M G+ KG+G V F + +A A+ +M G+ +G + +
Sbjct: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI 177
Score = 32.7 bits (73), Expect = 0.56
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+Y G + +TE ++ + F P G + R+ D GY +V F A A+ ++
Sbjct: 216 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 269
Query: 80 NFDLINGKPFRLMWSQ 95
N I G + W +
Sbjct: 270 NGTTIEGHVVKCYWGK 285
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 99.4 bits (246), Expect = 5e-21
Identities = 72/281 (25%), Positives = 130/281 (46%), Gaps = 31/281 (11%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD------NGSKG-----------YAYV 150
+++ NL + + + LFS G SCK++ + N S G Y +V
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 151 HFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDI 210
F A A+ MNG ++ ++V V P + +D + +VFV ++ +I
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQK-----KDTSNHFHVFVGDLSPEI 125
Query: 211 DDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVL 269
E +K F +G +V++D A+GKSKG+GFV + A+ A++ + G+ + G+ +
Sbjct: 126 TTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI 185
Query: 270 YVGRAQKKIER-LAELRRRFERLRLKE---KSRPPGVPIYIKNLDETINDEKLKEEFSSF 325
A +K + ++LR ++ +S P +Y + + D+ +++ FS F
Sbjct: 186 RTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPF 245
Query: 326 GSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIV 366
G I +V E KG+ V FS+ E A A+ +NG +
Sbjct: 246 GQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTI 282
Score = 97.4 bits (241), Expect = 2e-20
Identities = 80/282 (28%), Positives = 128/282 (45%), Gaps = 37/282 (13%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTR-ICRDPVTR---SPLG-----------YGYV 64
LYVG+L DVTE ++ + F GP + + I P +R S +G Y +V
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 65 NFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRK--SGVGNIFIKNLDKSIDNRAL 122
F DA AL MN I GK ++ W+ +K S ++F+ +L I +
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 130
Query: 123 FYLFSAFGNILSCKVVCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG-- 178
F+ FG I +VV D SKGY +V F + A AI HM G L RQ+
Sbjct: 131 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 190
Query: 179 RFKFPEERAAEVRTRDRATFTNV-----------FVKNIGDDIDDEKLKELFCEYGPTES 227
K P ++ + + F +V + I + D+ +++ F +G
Sbjct: 191 TRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIME 250
Query: 228 VKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVL 269
++V + KG+ FVR+ THE+A A++ ++G +I+G V+
Sbjct: 251 IRVFPE-----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 287
Score = 63.9 bits (154), Expect = 2e-10
Identities = 48/189 (25%), Positives = 84/189 (44%), Gaps = 32/189 (16%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDAS-----GKSKGFG-----------FV 244
++V N+ D+ + + +LF + GP +S K+I + S GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 245 RYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPI 304
+ H A A+ ++G+ I GK + V A + + F +
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFH--------------V 116
Query: 305 YIKNLDETINDEKLKEEFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMN 362
++ +L I E +K F+ FG IS A+V+ M G+ KG+G V F + +A A+ M
Sbjct: 117 FVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMG 176
Query: 363 GRIVGSKPL 371
G+ +G + +
Sbjct: 177 GQWLGGRQI 185
Score = 30.8 bits (68), Expect = 2.1
Identities = 18/84 (21%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+Y G + +T+ ++ + F P G + R+ + GY +V F A A+ ++
Sbjct: 224 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSV 277
Query: 80 NFDLINGKPFRLMWSQPDDRLRKS 103
N I G + W + + K+
Sbjct: 278 NGTTIEGHVVKCYWGKESPDMTKN 301
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 93.6 bits (231), Expect = 3e-19
Identities = 86/326 (26%), Positives = 146/326 (44%), Gaps = 35/326 (10%)
Query: 61 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 120
+GYV+F D E AL + G +L + D ++ + KNL +
Sbjct: 349 FGYVDFESAEDLEKALELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQD 407
Query: 121 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQV---YV 177
L +F I ++V D SKG AY+ F + A A + G ++ R + Y
Sbjct: 408 ELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYT 464
Query: 178 GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK 237
G ++ + + + N+ +E L+E+F + +KV ++ +GK
Sbjct: 465 GEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK 521
Query: 238 SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKS 297
SKG+ F+ + + E A++A+ + + I+G+ +R + R +
Sbjct: 522 SKGYAFIEFASFEDAKEALNSCNKREIEGRA---------------IRLELQGPRGSPNA 566
Query: 298 R-PPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEA 354
R P +++K L E +E LKE F GS+ RA+++ E G KGFG V F+S E+A
Sbjct: 567 RSQPSKTLFVKGLSEDTTEETLKESFD--GSV-RARIVTDRETGSSKGFGFVDFNSEEDA 623
Query: 355 TKAVDEM-NGRIVGSKPLHVTLGQAR 379
A + M +G I G+K VTL A+
Sbjct: 624 KAAKEAMEDGEIDGNK---VTLDWAK 646
Score = 71.2 bits (173), Expect = 1e-12
Identities = 81/288 (28%), Positives = 123/288 (42%), Gaps = 34/288 (11%)
Query: 8 PAGKKKKYLKAA--LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
P GK K + A L +L VT+D L + F A +R + +D ++ G Y+
Sbjct: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKDGKSK---GIAYIE 435
Query: 66 FRFPADAEWALNTMNFDLINGKPFRLMWS-----QPDDRLRKSGVGN-----IFIKNLDK 115
F+ ADAE I+G+ L ++ D R K+ + + + NL
Sbjct: 436 FKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
Query: 116 SIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQ 174
S L +F I KV + NG SKGYA++ F S A A+ N + R
Sbjct: 496 SATEETLQEVFEKATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRA 552
Query: 175 VYV---GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVI 231
+ + G P R+ +T +FVK + +D +E LKE F G + V
Sbjct: 553 IRLELQGPRGSPNARSQPSKT--------LFVKGLSEDTTEETLKESFD--GSVRARIVT 602
Query: 232 RDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIE 279
+G SKGFGFV + + E A+ A + IDG + + A+ K E
Sbjct: 603 DRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 20/189 (10%)
Query: 183 PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
PE + +V + T N+FV N+ + +LK + + V+ G ++ FG
Sbjct: 291 PEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFG 350
Query: 243 FVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGV 302
+V +E+ E +KA L+L G + G + + + + K K
Sbjct: 351 YVDFESAEDLEKA-LELTGLKVFGNEIKLEKPKGK----------------DSKKERDAR 393
Query: 303 PIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMN 362
+ KNL + ++LKE F I +++ + G+ KG + F + +A K +E
Sbjct: 394 TLLAKNLPYKVTQDELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQ 450
Query: 363 GRIVGSKPL 371
G + + +
Sbjct: 451 GTEIDGRSI 459
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 4 GEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGY 63
G PN + K L+V L D TE+ L + F G +R RI D T S G+G+
Sbjct: 562 GSPNARSQPSK----TLFVKGLSEDTTEETLKESFD--GSVR-ARIVTDRETGSSKGFGF 614
Query: 64 VNFRFPADAEWALNTMNFDLINGKPFRLMWSQP 96
V+F DA+ A M I+G L W++P
Sbjct: 615 VDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKP 647
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 90.1 bits (222), Expect = 3e-18
Identities = 80/320 (25%), Positives = 150/320 (46%), Gaps = 61/320 (19%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ L LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 100 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 150
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDG-----KVLYVGRAQKKI 278
+ +++ D +G S+G GF+R++ A++A+ L+G+ G V + +K
Sbjct: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKT 210
Query: 279 ER--LAEL----RRRF--------ERLRLK---------EKSRP--------------PG 301
+ L++L RR+ +R RL ++ P PG
Sbjct: 211 NQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPG 270
Query: 302 VP-----IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
P I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 271 HPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEA 330
Query: 355 TKAVDEMNGRIVGSKPLHVT 374
A+ +NG +G + L V+
Sbjct: 331 AMAIASLNGYRLGDRVLQVS 350
Score = 82.0 bits (201), Expect = 8e-16
Identities = 46/153 (30%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Query: 17 KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76
K L V L ++T++ L F G + ++ RD +T LGYG+VN+ P DAE A+
Sbjct: 38 KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
Query: 77 NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136
NT+N + K ++ +++P + N+++ L K++ + L LFS +G I++ +
Sbjct: 98 NTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSR 155
Query: 137 VVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
++ D S+G ++ FD A AI +NG
Sbjct: 156 ILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 73.9 bits (180), Expect = 2e-13
Identities = 46/169 (27%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ E+LK LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 39 TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 99 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 140
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
Score = 52.8 bits (125), Expect = 5e-07
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
+FV N+ D D+ L ++F +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 260 HGKSIDGKVLYVGRAQKKIER 280
+G + +VL V K +
Sbjct: 338 NGYRLGDRVLQVSFKTNKTHK 358
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 80 N 80
N
Sbjct: 338 N 338
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 88.2 bits (217), Expect = 1e-17
Identities = 73/327 (22%), Positives = 150/327 (45%), Gaps = 62/327 (18%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G+I SCK+V D S GY +V++ A++AI
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG++L + + V + +A +R N++V + + +++++LF +YG
Sbjct: 100 LNGLKLQTKTIKV---SYARPSSASIRD------ANLYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKV--------------- 268
+ +++ D +G S+G GF+R++ A++A+ L+G+ G
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 269 -------LYVGRAQK------------KIERLAELR---RRFERLRLKEKSRPPGVP--- 303
LY A++ +++ L + +RF + + S GV
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSG 270
Query: 304 --------IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEE 353
I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++E
Sbjct: 271 GAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDE 330
Query: 354 ATKAVDEMNGRIVGSKPLHVTLGQARR 380
A A+ +NG +G + L V+ +++
Sbjct: 331 AAMAIASLNGYRLGERVLQVSFKTSKQ 357
Score = 81.3 bits (199), Expect = 1e-15
Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 4/153 (2%)
Query: 17 KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76
K L V L ++T+D F G + ++ RD +T LGYG+VN+ P DA+ A+
Sbjct: 38 KTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAI 97
Query: 77 NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136
NT+N + K ++ +++P + N+++ L K++ + + LFS +G I++ +
Sbjct: 98 NTLNGLKLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMSQKEMEQLFSQYGRIITSR 155
Query: 137 VVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
++ D S+G ++ FD A AI +NG
Sbjct: 156 ILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 72.0 bits (175), Expect = 8e-13
Identities = 46/176 (26%), Positives = 87/176 (49%), Gaps = 25/176 (14%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ ++ K LF G ES K++RD +G+S G+GFV Y A KA+
Sbjct: 39 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 98
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T++ ++
Sbjct: 99 TLNGLKLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMSQKE 140
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
+++ FS +G I ++++++ G +G G + F EA +A+ +NG+ KPL
Sbjct: 141 MEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ----KPL 192
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCD--DNGSKGYAYVHFDSLAAANRAIWHM 165
IF+ NL D L+ LF FG + + KV+ D N KG+ +V + A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 166 NGVRLNNRQVYVGRFKFPEERAA 188
NG RL R + V FK ++ A
Sbjct: 339 NGYRLGERVLQVS-FKTSKQHKA 360
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/61 (27%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L P+ E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 80 N 80
N
Sbjct: 339 N 339
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 87.0 bits (214), Expect = 2e-17
Identities = 76/320 (23%), Positives = 142/320 (44%), Gaps = 61/320 (19%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 110 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 160
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV------GRAQKK 277
+ +++ D +G S+G GF+R++ A++A+ L+G+ G + +QK
Sbjct: 161 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 220
Query: 278 IERL-------------AELRRRFERLRLKE--------KSRPP---------------- 300
+ L L + +R RL K P
Sbjct: 221 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 280
Query: 301 ----GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
G I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 281 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 340
Query: 355 TKAVDEMNGRIVGSKPLHVT 374
A+ +NG +G + L V+
Sbjct: 341 AMAIASLNGYRLGDRVLQVS 360
Score = 81.3 bits (199), Expect = 1e-15
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 6 PNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
P G K L V L ++T++ F G + ++ RD +T LGYG+VN
Sbjct: 37 PMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVN 96
Query: 66 FRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYL 125
+ P DAE A+NT+N + K ++ +++P + N+++ L K++ + L L
Sbjct: 97 YIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQL 154
Query: 126 FSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
FS +G I++ +++ D S+G ++ FD A AI +NG
Sbjct: 155 FSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 198
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 21/169 (12%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ E+ + LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 49 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 109 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 150
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 199
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
+FV N+ D D+ L +LF +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 260 HGKSIDGKVLYVGRAQKKIER 280
+G + +VL V K +
Sbjct: 348 NGYRLGDRVLQVSFKTNKAHK 368
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 80 N 80
N
Sbjct: 348 N 348
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 87.0 bits (214), Expect = 2e-17
Identities = 76/320 (23%), Positives = 142/320 (44%), Gaps = 61/320 (19%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 107 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV------GRAQKK 277
+ +++ D +G S+G GF+R++ A++A+ L+G+ G + +QK
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 278 IERL-------------AELRRRFERLRLKE--------KSRPP---------------- 300
+ L L + +R RL K P
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 301 ----GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
G I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 355 TKAVDEMNGRIVGSKPLHVT 374
A+ +NG +G + L V+
Sbjct: 338 AMAIASLNGYRLGDRVLQVS 357
Score = 81.3 bits (199), Expect = 1e-15
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 6 PNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
P G K L V L ++T++ F G + ++ RD +T LGYG+VN
Sbjct: 34 PMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVN 93
Query: 66 FRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYL 125
+ P DAE A+NT+N + K ++ +++P + N+++ L K++ + L L
Sbjct: 94 YIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQL 151
Query: 126 FSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
FS +G I++ +++ D S+G ++ FD A AI +NG
Sbjct: 152 FSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 21/169 (12%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ E+ + LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 147
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 196
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
+FV N+ D D+ L +LF +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 260 HGKSIDGKVLYVGRAQKKIER 280
+G + +VL V K +
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHK 365
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 80 N 80
N
Sbjct: 345 N 345
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 87.0 bits (214), Expect = 2e-17
Identities = 76/320 (23%), Positives = 142/320 (44%), Gaps = 61/320 (19%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 124 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 174
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV------GRAQKK 277
+ +++ D +G S+G GF+R++ A++A+ L+G+ G + +QK
Sbjct: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
Query: 278 IERL-------------AELRRRFERLRLKE--------KSRPP---------------- 300
+ L L + +R RL K P
Sbjct: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
Query: 301 ----GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
G I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
Query: 355 TKAVDEMNGRIVGSKPLHVT 374
A+ +NG +G + L V+
Sbjct: 355 AMAIASLNGYRLGDRVLQVS 374
Score = 81.3 bits (199), Expect = 1e-15
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 6 PNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
P G K L V L ++T++ F G + ++ RD +T LGYG+VN
Sbjct: 51 PMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVN 110
Query: 66 FRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYL 125
+ P DAE A+NT+N + K ++ +++P + N+++ L K++ + L L
Sbjct: 111 YIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQL 168
Query: 126 FSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
FS +G I++ +++ D S+G ++ FD A AI +NG
Sbjct: 169 FSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 21/169 (12%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ E+ + LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 123 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 164
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 213
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
+FV N+ D D+ L +LF +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 260 HGKSIDGKVLYVGRAQKKIER 280
+G + +VL V K +
Sbjct: 362 NGYRLGDRVLQVSFKTNKAHK 382
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 80 N 80
N
Sbjct: 362 N 362
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 87.0 bits (214), Expect = 2e-17
Identities = 76/320 (23%), Positives = 142/320 (44%), Gaps = 61/320 (19%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 107 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV------GRAQKK 277
+ +++ D +G S+G GF+R++ A++A+ L+G+ G + +QK
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 278 IERL-------------AELRRRFERLRLKE--------KSRPP---------------- 300
+ L L + +R RL K P
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 301 ----GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
G I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 355 TKAVDEMNGRIVGSKPLHVT 374
A+ +NG +G + L V+
Sbjct: 338 AMAIASLNGYRLGDRVLQVS 357
Score = 81.3 bits (199), Expect = 1e-15
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 6 PNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
P G K L V L ++T++ F G + ++ RD +T LGYG+VN
Sbjct: 34 PMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVN 93
Query: 66 FRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYL 125
+ P DAE A+NT+N + K ++ +++P + N+++ L K++ + L L
Sbjct: 94 YIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQL 151
Query: 126 FSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
FS +G I++ +++ D S+G ++ FD A AI +NG
Sbjct: 152 FSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 21/169 (12%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ E+ + LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 147
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 196
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
+FV N+ D D+ L +LF +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 260 HGKSIDGKVLYVGRAQKKIER 280
+G + +VL V K +
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHK 365
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 80 N 80
N
Sbjct: 345 N 345
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 84.7 bits (208), Expect = 1e-16
Identities = 58/200 (29%), Positives = 101/200 (50%), Gaps = 22/200 (11%)
Query: 183 PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGF 241
P + A R R A V+V +I ++ ++ +++ F +GP +S+ + D+ + K KGF
Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129
Query: 242 GFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR------AQKKIERLAELRRRFERLRLKE 295
FV YE EAAQ A+ ++ + G+ + VGR AQ I++LAE R F R
Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR----- 184
Query: 296 KSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEE 353
IY+ ++ + ++D+ +K F +FG I + + G+ KG+G + + +
Sbjct: 185 --------IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQS 236
Query: 354 ATKAVDEMNGRIVGSKPLHV 373
+ AV MN +G + L V
Sbjct: 237 SQDAVSSMNLFDLGGQYLRV 256
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/208 (26%), Positives = 99/208 (47%), Gaps = 10/208 (4%)
Query: 73 EWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVG-NIFIKNLDKSIDNRALFYLFSAFGN 131
+ A TM F G P + S R R + +++ ++ + + F+ FG
Sbjct: 56 QMAAVTMGF----GDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGP 111
Query: 132 ILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKF--PEERA 187
I S + D KG+A+V ++ AA A+ MN V L R + VGR +
Sbjct: 112 IKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPI 171
Query: 188 AEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRY 246
+ + F ++V ++ D+ D+ +K +F +G +S + RD +GK KG+GF+ Y
Sbjct: 172 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 231
Query: 247 ETHEAAQKAVLDLHGKSIDGKVLYVGRA 274
E +++Q AV ++ + G+ L VG+A
Sbjct: 232 EKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 70.1 bits (170), Expect = 3e-12
Identities = 51/201 (25%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 1 MGSGEP-----NPAGKKKKYLK--AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDP 53
MG G+P + A ++++ L +YVG + ++ ED + + F P GP++ + D
Sbjct: 62 MGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDS 121
Query: 54 VTRSPLGYGYVNFRFPADAEWALNTMNFDLIN------GKPFRLMWSQP-DDRLRKS--G 104
VT G+ +V + P A+ AL MN ++ G+P + +QP D+L +
Sbjct: 122 VTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARA 181
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS--KGYAYVHFDSLAAANRAI 162
I++ ++ + + + + +F AFG I SC + D KGY ++ ++ ++ A+
Sbjct: 182 FNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAV 241
Query: 163 WHMNGVRLNNRQVYVGRFKFP 183
MN L + + VG+ P
Sbjct: 242 SSMNLFDLGGQYLRVGKAVTP 262
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 84.7 bits (208), Expect = 1e-16
Identities = 58/200 (29%), Positives = 101/200 (50%), Gaps = 22/200 (11%)
Query: 183 PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGF 241
P + A R R A V+V +I ++ ++ +++ F +GP +S+ + D+ + K KGF
Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
Query: 242 GFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR------AQKKIERLAELRRRFERLRLKE 295
FV YE EAAQ A+ ++ + G+ + VGR AQ I++LAE R F R
Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR----- 227
Query: 296 KSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEE 353
IY+ ++ + ++D+ +K F +FG I + + G+ KG+G + + +
Sbjct: 228 --------IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQS 279
Query: 354 ATKAVDEMNGRIVGSKPLHV 373
+ AV MN +G + L V
Sbjct: 280 SQDAVSSMNLFDLGGQYLRV 299
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/208 (26%), Positives = 99/208 (47%), Gaps = 10/208 (4%)
Query: 73 EWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVG-NIFIKNLDKSIDNRALFYLFSAFGN 131
+ A TM F G P + S R R + +++ ++ + + F+ FG
Sbjct: 99 QMAAVTMGF----GDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGP 154
Query: 132 ILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKF--PEERA 187
I S + D KG+A+V ++ AA A+ MN V L R + VGR +
Sbjct: 155 IKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPI 214
Query: 188 AEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRY 246
+ + F ++V ++ D+ D+ +K +F +G +S + RD +GK KG+GF+ Y
Sbjct: 215 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 274
Query: 247 ETHEAAQKAVLDLHGKSIDGKVLYVGRA 274
E +++Q AV ++ + G+ L VG+A
Sbjct: 275 EKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 70.1 bits (170), Expect = 3e-12
Identities = 51/201 (25%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 1 MGSGEP-----NPAGKKKKYLK--AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDP 53
MG G+P + A ++++ L +YVG + ++ ED + + F P GP++ + D
Sbjct: 105 MGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDS 164
Query: 54 VTRSPLGYGYVNFRFPADAEWALNTMNFDLIN------GKPFRLMWSQP-DDRLRKS--G 104
VT G+ +V + P A+ AL MN ++ G+P + +QP D+L +
Sbjct: 165 VTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARA 224
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS--KGYAYVHFDSLAAANRAI 162
I++ ++ + + + + +F AFG I SC + D KGY ++ ++ ++ A+
Sbjct: 225 FNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAV 284
Query: 163 WHMNGVRLNNRQVYVGRFKFP 183
MN L + + VG+ P
Sbjct: 285 SSMNLFDLGGQYLRVGKAVTP 305
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 84.7 bits (208), Expect = 1e-16
Identities = 74/334 (22%), Positives = 145/334 (43%), Gaps = 69/334 (20%)
Query: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
N+ + L +++ LF + G+I SCK+V D S GY +V++ A++AI
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
+NG++L + + V + +A +R N++V + + +++++LF +YG
Sbjct: 100 LNGLKLQTKTIKV---SYARPSSASIRD------ANLYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGK------------------SID 265
+ +++ D +G S+G GF+R++ A++A+ L+G+
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 266 GKVLYVGRAQKKIERLA--------------------------ELRRRFERLRLKEKSRP 299
G+ L Q R A L RF + + S
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGL 270
Query: 300 PGVP-----------IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVV 346
GV I++ NL ++ L + F FG+++ KV+ + + KGFG V
Sbjct: 271 AGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFV 330
Query: 347 CFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARR 380
++++EA A+ +NG +G + L V+ +++
Sbjct: 331 TMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQ 364
Score = 81.3 bits (199), Expect = 1e-15
Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 4/153 (2%)
Query: 17 KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76
K L V L ++T+D F G + ++ RD +T LGYG+VN+ P DA+ A+
Sbjct: 38 KTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAI 97
Query: 77 NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136
NT+N + K ++ +++P + N+++ L K++ + + LFS +G I++ +
Sbjct: 98 NTLNGLKLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMSQKEMEQLFSQYGRIITSR 155
Query: 137 VVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
++ D S+G ++ FD A AI +NG
Sbjct: 156 ILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 72.0 bits (175), Expect = 8e-13
Identities = 46/176 (26%), Positives = 87/176 (49%), Gaps = 25/176 (14%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
TN+ V + ++ ++ K LF G ES K++RD +G+S G+GFV Y A KA+
Sbjct: 39 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 98
Query: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
L+G + K + V A+ + + +Y+ L +T++ ++
Sbjct: 99 TLNGLKLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMSQKE 140
Query: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
+++ FS +G I ++++++ G +G G + F EA +A+ +NG+ KPL
Sbjct: 141 MEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ----KPL 192
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCD--DNGSKGYAYVHFDSLAAANRAIWHM 165
IF+ NL D L+ LF FG + + KV+ D N KG+ +V + A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 166 NGVRLNNRQVYVGRFKFPEERAA 188
NG RL R + V FK ++ A
Sbjct: 346 NGYRLGERVLQVS-FKTSKQHKA 367
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/61 (27%), Positives = 33/61 (54%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
++V +L P+ E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 80 N 80
N
Sbjct: 346 N 346
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 83.2 bits (204), Expect = 4e-16
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 22/195 (11%)
Query: 188 AEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRY 246
A R R A V+V +I ++ ++ +++ F +GP +S+ + D+ + K KGF FV Y
Sbjct: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEY 160
Query: 247 ETHEAAQKAVLDLHGKSIDGKVLYVGR------AQKKIERLAELRRRFERLRLKEKSRPP 300
E EAAQ A+ ++ + G+ + VGR AQ I++LAE R F R
Sbjct: 161 EVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR---------- 210
Query: 301 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAV 358
IY+ ++ + ++D+ +K F +FG I + + G+ KG+G + + + + AV
Sbjct: 211 ---IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAV 267
Query: 359 DEMNGRIVGSKPLHV 373
MN +G + L V
Sbjct: 268 SSMNLFDLGGQYLRV 282
Score = 76.3 bits (186), Expect = 4e-14
Identities = 47/172 (27%), Positives = 87/172 (50%), Gaps = 5/172 (2%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHM 165
+++ ++ + + F+ FG I S + D KG+A+V ++ AA A+ M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 166 NGVRLNNRQVYVGRFKF--PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYG 223
N V L R + VGR + + + F ++V ++ D+ D+ +K +F +G
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 224 PTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRA 274
+S + RD +GK KG+GF+ YE +++Q AV ++ + G+ L VG+A
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
Score = 68.6 bits (166), Expect = 9e-12
Identities = 45/175 (25%), Positives = 85/175 (48%), Gaps = 11/175 (6%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
+YVG + ++ ED + + F P GP++ + D VT G+ +V + P A+ AL M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 80 NFDLIN------GKPFRLMWSQP-DDRLRKS--GVGNIFIKNLDKSIDNRALFYLFSAFG 130
N ++ G+P + +QP D+L + I++ ++ + + + + +F AFG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 131 NILSCKVVCDDNGS--KGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFP 183
I SC + D KGY ++ ++ ++ A+ MN L + + VG+ P
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTP 288
>gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b
[Homo sapiens]
Length = 691
Score = 82.8 bits (203), Expect = 5e-16
Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 12/178 (6%)
Query: 202 FVKNIGDDIDDEKLKELFCE-YGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
F+ NI D+ + LK+L E G V+++ DA GKS+G V ++ E+ +KA L+
Sbjct: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLN 133
Query: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
S+ G+ L V K + E RR +K+ G +++ NLD + +KLKE
Sbjct: 134 KHSLSGRPLKV-----KEDPDGEHARR-----AMQKAGRLGSTVFVANLDYKVGWKKLKE 183
Query: 321 EFSSFGSISRAKVMMEV-GQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
FS G + RA ++ + G+ +G G V F EA +A+ NG+++ +P+HV + +
Sbjct: 184 VFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDE 241
Score = 48.1 bits (113), Expect = 1e-05
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 130 GNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAA 188
G + +++ D G S+G A V F + +A +N L+ R + V E
Sbjct: 96 GEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARR 155
Query: 189 EVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYET 248
++ R T VFV N+ + +KLKE+F G ++ D GKS+G G V +E
Sbjct: 156 AMQKAGRLGST-VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQ 214
Query: 249 HEAAQKAVLDLHGKSIDGKVLYVGRAQKKIER 280
A +A+ +G+ + + ++V ++ + +
Sbjct: 215 SIEAVQAISMFNGQLLFDRPMHVKMDERALPK 246
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNG 363
I+++NL + LK++F+ G + A + ME G+ KG GVV F S E A +A MNG
Sbjct: 616 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 675
Query: 364 RIVGSKPLHVTL 375
+ + + V +
Sbjct: 676 MKLSGREIDVRI 687
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 20/166 (12%)
Query: 42 GPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDR-- 99
G + + + D +S G V F+ + A +N ++G+P ++ PD
Sbjct: 96 GEVTYVELLMDAEGKSR-GCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVK-EDPDGEHA 153
Query: 100 ---LRKSGV--GNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFD 153
++K+G +F+ NLD + + L +FS G ++ ++ D +G S+G V F+
Sbjct: 154 RRAMQKAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFE 213
Query: 154 SLAAANRAIWHMNG---------VRLNNRQVYVGRFKFPEERAAEV 190
A +AI NG V+++ R + G F FP ER ++
Sbjct: 214 QSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDF-FPPERPQQL 258
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/70 (32%), Positives = 38/70 (54%)
Query: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
IF++NL + L F+ G++L + ++ SKG V F+S A RA MNG
Sbjct: 616 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 675
Query: 168 VRLNNRQVYV 177
++L+ R++ V
Sbjct: 676 MKLSGREIDV 685
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
+FV+N+ D + LK+ F E G I+ +GKSKG G V++E+ E A++A ++
Sbjct: 616 IFVRNLPFDFTWKMLKDKFNECGHVLYAD-IKMENGKSKGCGVVKFESPEVAERACRMMN 674
Query: 261 GKSIDGKVLYV 271
G + G+ + V
Sbjct: 675 GMKLSGREIDV 685
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 82.0 bits (201), Expect = 8e-16
Identities = 55/188 (29%), Positives = 92/188 (48%), Gaps = 12/188 (6%)
Query: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK--- 237
K EE E + +F+KN+ D +EKLKE+F + G +S + + +
Sbjct: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
Query: 238 -SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEK 296
S GFGFV Y E AQKA+ L G +DG L V +++ + L R+ + R +
Sbjct: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
Query: 297 SRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRA---KVMMEVGQGKGFGVVCFSSFEE 353
S+ I ++N+ + +++E FS+FG + K M G +GFG V F + ++
Sbjct: 832 SK-----ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQD 886
Query: 354 ATKAVDEM 361
A +A + +
Sbjct: 887 AKRAFNAL 894
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/213 (23%), Positives = 97/213 (45%), Gaps = 24/213 (11%)
Query: 178 GRFKFPEERAAEVRT---RDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA 234
G+ + PE RA + ++ T V ++ ++ ++ + E P +++++R+A
Sbjct: 270 GKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPV-AIRIVRNA 328
Query: 235 SGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR---------AQKKIERLAE-- 283
G G+ FV + E ++A L + + + G+ + V R A K + +
Sbjct: 329 HGNKTGYIFVDFSNEEEVKQA-LKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGR 387
Query: 284 -LRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQG 340
L E L E R ++++NL T +E L++ FS +G +S ++ +
Sbjct: 388 ILGENEEEEDLAESGR-----LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKP 442
Query: 341 KGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
KGF + F E A KA E++G++ + LHV
Sbjct: 443 KGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
Score = 52.4 bits (124), Expect = 7e-07
Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 294 KEKSRPPGVPIYIKNLDETINDEKLKEEFSSFG-----SISRAKVMMEVGQGKGFGVVCF 348
+E+ PG ++IKNL+ +EKLKE FS G SIS+ K V GFG V +
Sbjct: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
Query: 349 SSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
E+A KA+ ++ G +V L V + +
Sbjct: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISE 810
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 23/174 (13%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPL---GYGYVNFRFPADAEWAL 76
L++ +L+ D TE+ L + F G ++ I + L G+G+V +R P A+ AL
Sbjct: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
Query: 77 NTMNFDLINGKPFRLMWSQPDDR-----------LRKSGVGNIFIKNLDKSIDNRALFYL 125
+ +++G + S+ + RK I ++N+ +R + L
Sbjct: 792 KQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIREL 851
Query: 126 FSAFGNILSCKVVCDDNGS---KGYAYVHFDSLAAANRAI------WHMNGVRL 170
FS FG + + ++ G+ +G+ +V F + A RA H+ G RL
Sbjct: 852 FSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258
+ + VKN+ + + +E+ ++LF +G + GK + FGF+ +++ E AQKA
Sbjct: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
Query: 259 LHGKSID 265
+ ID
Sbjct: 62 FNKSFID 68
Score = 38.5 bits (88), Expect = 0.010
Identities = 21/73 (28%), Positives = 36/73 (49%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
L+V +L TE+ L K F GPL D +T+ P G+ ++ F FP A A + +
Sbjct: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
Query: 80 NFDLINGKPFRLM 92
+ + G+ ++
Sbjct: 464 DGQVFQGRMLHVL 476
Score = 37.0 bits (84), Expect = 0.030
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKV-MMEVGQGKGFGVVCFSSFEEATKAVDEMN 362
+ +KNL + +E+ ++ F++FG+++ + + G+ + FG + F S EEA KA N
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 363 GRIVGSKPLHV 373
+ + + V
Sbjct: 64 KSFIDTSRITV 74
Score = 32.3 bits (72), Expect = 0.73
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIW 163
+ + +KNL + LF+AFG + C + +G + + ++ F S A +A
Sbjct: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
Query: 164 HMNGVRLNNRQVYV 177
H N ++ ++ V
Sbjct: 61 HFNKSFIDTSRITV 74
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 82.0 bits (201), Expect = 8e-16
Identities = 55/188 (29%), Positives = 92/188 (48%), Gaps = 12/188 (6%)
Query: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK--- 237
K EE E + +F+KN+ D +EKLKE+F + G +S + + +
Sbjct: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
Query: 238 -SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEK 296
S GFGFV Y E AQKA+ L G +DG L V +++ + L R+ + R +
Sbjct: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
Query: 297 SRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRA---KVMMEVGQGKGFGVVCFSSFEE 353
S+ I ++N+ + +++E FS+FG + K M G +GFG V F + ++
Sbjct: 832 SK-----ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQD 886
Query: 354 ATKAVDEM 361
A +A + +
Sbjct: 887 AKRAFNAL 894
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/213 (23%), Positives = 97/213 (45%), Gaps = 24/213 (11%)
Query: 178 GRFKFPEERAAEVRT---RDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA 234
G+ + PE RA + ++ T V ++ ++ ++ + E P +++++R+A
Sbjct: 270 GKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPV-AIRIVRNA 328
Query: 235 SGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR---------AQKKIERLAE-- 283
G G+ FV + E ++A L + + + G+ + V R A K + +
Sbjct: 329 HGNKTGYIFVDFSNEEEVKQA-LKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGR 387
Query: 284 -LRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQG 340
L E L E R ++++NL T +E L++ FS +G +S ++ +
Sbjct: 388 ILGENEEEEDLAESGR-----LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKP 442
Query: 341 KGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
KGF + F E A KA E++G++ + LHV
Sbjct: 443 KGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
Score = 52.4 bits (124), Expect = 7e-07
Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 294 KEKSRPPGVPIYIKNLDETINDEKLKEEFSSFG-----SISRAKVMMEVGQGKGFGVVCF 348
+E+ PG ++IKNL+ +EKLKE FS G SIS+ K V GFG V +
Sbjct: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
Query: 349 SSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
E+A KA+ ++ G +V L V + +
Sbjct: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISE 810
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 23/174 (13%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPL---GYGYVNFRFPADAEWAL 76
L++ +L+ D TE+ L + F G ++ I + L G+G+V +R P A+ AL
Sbjct: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
Query: 77 NTMNFDLINGKPFRLMWSQPDDR-----------LRKSGVGNIFIKNLDKSIDNRALFYL 125
+ +++G + S+ + RK I ++N+ +R + L
Sbjct: 792 KQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIREL 851
Query: 126 FSAFGNILSCKVVCDDNGS---KGYAYVHFDSLAAANRAI------WHMNGVRL 170
FS FG + + ++ G+ +G+ +V F + A RA H+ G RL
Sbjct: 852 FSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258
+ + VKN+ + + +E+ ++LF +G + GK + FGF+ +++ E AQKA
Sbjct: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
Query: 259 LHGKSID 265
+ ID
Sbjct: 62 FNKSFID 68
Score = 38.5 bits (88), Expect = 0.010
Identities = 21/73 (28%), Positives = 36/73 (49%)
Query: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
L+V +L TE+ L K F GPL D +T+ P G+ ++ F FP A A + +
Sbjct: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
Query: 80 NFDLINGKPFRLM 92
+ + G+ ++
Sbjct: 464 DGQVFQGRMLHVL 476
Score = 37.0 bits (84), Expect = 0.030
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKV-MMEVGQGKGFGVVCFSSFEEATKAVDEMN 362
+ +KNL + +E+ ++ F++FG+++ + + G+ + FG + F S EEA KA N
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 363 GRIVGSKPLHV 373
+ + + V
Sbjct: 64 KSFIDTSRITV 74
Score = 32.3 bits (72), Expect = 0.73
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIW 163
+ + +KNL + LF+AFG + C + +G + + ++ F S A +A
Sbjct: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
Query: 164 HMNGVRLNNRQVYV 177
H N ++ ++ V
Sbjct: 61 HFNKSFIDTSRITV 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,703,325
Number of Sequences: 37866
Number of extensions: 655135
Number of successful extensions: 3383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 236
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 1653
Number of HSP's gapped (non-prelim): 1083
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.