NGEF 6860

Name: NGEF	Sequence: fasta or formatted (618aa)		NCBI GI: 166197690
Description: neuronal guanine nucleotide exchange factor isoform 2		Referenced in: Neurons Rho and Rac
Other entries for this name: alt prot [710aa] neuronal guanine nucleotide exchange factor isoform 1
Composition: Amino acid Percentage Count Longest homopolymer A alanine 6.0 37 3 C cysteine 1.6 10 1 D aspartate 5.3 33 2 E glutamate 11.0 68 11 F phenylalanine 3.6 22 1 G glycine 2.9 18 1 H histidine 2.4 15 1 I isoleucine 5.7 35 2 K lysine 5.0 31 2 L leucine 11.7 72 2 M methionine 2.4 15 1 N asparagine 3.6 22 1 P proline 5.0 31 2 Q glutamine 5.7 35 2 R arginine 7.3 45 2 S serine 8.4 52 3 T threonine 4.7 29 2 V valine 4.4 27 2 W tryptophan 1.1 7 1 Y tyrosine 2.3 14 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 neuronal guanine nucleotide exchange factor isoform... NGEF 0.944 neuronal guanine nucleotide exchange factor isoform... ARHGEF5 0.287 rho guanine nucleotide exchange factor 5 ARHGEF19 0.286 Rho guanine nucleotide exchange factor (GEF) 19 [Hom... ARHGEF16 0.248 Rho guanine exchange factor 16 SGEF 0.243 Src homology 3 domain-containing guanine nucleotide... ARHGEF15 0.215 Rho guanine exchange factor 15 ITSN1 0.068 intersectin 1 isoform ITSN-l ITSN2 0.065 intersectin 2 isoform 3 ITSN2 0.065 intersectin 2 isoform 1 FGD1 0.061 faciogenital dysplasia protein FGD4 0.060 FYVE, RhoGEF and PH domain containing 4 ARHGEF12 0.051 Rho guanine nucleotide exchange factor (GEF) 12 [Homo... FGD3 0.049 FYVE, RhoGEF and PH domain containing 3 FGD3 0.049 FYVE, RhoGEF and PH domain containing 3 VAV2 0.048 vav 2 guanine nucleotide exchange factor isoform 2 [... PLEKHG5 0.047 pleckstrin homology domain containing family G membe... PLEKHG5 0.047 pleckstrin homology domain containing family G memb... PLEKHG5 0.047 pleckstrin homology domain containing family G memb... PLEKHG5 0.047 pleckstrin homology domain containing family G memb... PLEKHG5 0.047 pleckstrin homology domain containing family G memb... FGD2 0.047 FYVE, RhoGEF and PH domain containing 2 ARHGEF11 0.046 Rho guanine nucleotide exchange factor (GEF) 11 isof... ARHGEF11 0.046 Rho guanine nucleotide exchange factor (GEF) 11 isofo... ARHGEF1 0.046 Rho guanine nucleotide exchange factor 1 isoform 1 [... ARHGEF1 0.046 Rho guanine nucleotide exchange factor 1 isoform 3 [... ARHGEF1 0.046 Rho guanine nucleotide exchange factor 1 isoform 2 [... VAV2 0.046 vav 2 guanine nucleotide exchange factor isoform 1 ... PREX1 0.039 phosphatidylinositol-3,4,5-trisphosphate-dependent R... PREX2 0.039 DEP domain containing 2 isoform b Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.