Guide to the Human Genome
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Name: ARHGEF5 Sequence: fasta or formatted (1597aa) NCBI GI: 50959191
Description:

rho guanine nucleotide exchange factor 5

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6        106           2
 C cysteine            1.3         21           1
 D aspartate           3.8         61           2
 E glutamate          10.1        162           5
 F phenylalanine       2.8         44           1
 G glycine             5.9         95           2
 H histidine           2.8         45           2
 I isoleucine          2.6         41           2
 K lysine              3.4         55           2
 L leucine             8.7        139           3
 M methionine          1.6         25           1
 N asparagine          2.6         42           3
 P proline            10.1        162           5
 Q glutamine           6.5        104           2
 R arginine            7.0        112           2
 S serine             11.5        184           2
 T threonine           5.0         80           2
 V valine              4.8         77           3
 W tryptophan          1.2         19           1
 Y tyrosine            1.4         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   rho guanine nucleotide exchange factor 5 
ARHGEF5L              0.292   Rho guanine nucleotide exchange factor (GEF) 5-like ...
ARHGEF19              0.146   Rho guanine nucleotide exchange factor (GEF) 19 [Hom...
NGEF                  0.108   neuronal guanine nucleotide exchange factor isoform...
NGEF                  0.108   neuronal guanine nucleotide exchange factor isoform...
ARHGEF16              0.084   Rho guanine exchange factor 16 
SGEF                  0.082   Src homology 3 domain-containing guanine nucleotide...
ARHGEF15              0.076   Rho guanine exchange factor 15 
FGD2                  0.020   FYVE, RhoGEF and PH domain containing 2 
FGD4                  0.018   FYVE, RhoGEF and PH domain containing 4 
FLJ22184              0.018   PREDICTED: hypothetical protein LOC80164 
FGD1                  0.018   faciogenital dysplasia protein 
FLJ22184              0.018   PREDICTED: hypothetical protein FLJ22184 
ITSN2                 0.018   intersectin 2 isoform 3 
ITSN2                 0.018   intersectin 2 isoform 1 
FLJ22184              0.017   PREDICTED: hypothetical protein FLJ22184 
ARHGEF11              0.017   Rho guanine nucleotide exchange factor (GEF) 11 isof...
ARHGEF11              0.017   Rho guanine nucleotide exchange factor (GEF) 11 isofo...
MDC1                  0.017   mediator of DNA-damage checkpoint 1 
ITSN1                 0.017   intersectin 1 isoform ITSN-l 
ECT2                  0.017   epithelial cell transforming sequence 2 oncogene pro...
PRG4                  0.016   proteoglycan 4 isoform D 
PRG4                  0.016   proteoglycan 4 isoform C 
PRG4                  0.016   proteoglycan 4 isoform B 
PRG4                  0.016   proteoglycan 4 isoform A 
MUC2                  0.015   mucin 2 precursor 
RPGR                  0.015   retinitis pigmentosa GTPase regulator isoform C [Hom...
SETD1B                0.015   SET domain containing 1B 
MLL2                  0.015   myeloid/lymphoid or mixed-lineage leukemia 2 
ARHGEF1               0.015   Rho guanine nucleotide exchange factor 1 isoform 1 [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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