BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] (550 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 1137 0.0 gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 1105 0.0 gi|134288906 tripartite motif-containing 67 [Homo sapiens] 692 0.0 gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 190 3e-48 gi|47174859 tripartite motif-containing 46 [Homo sapiens] 171 1e-42 gi|223890259 midline 2 isoform 2 [Homo sapiens] 163 3e-40 gi|223890257 midline 2 isoform 1 [Homo sapiens] 159 5e-39 gi|148833499 midline 1 [Homo sapiens] 149 8e-36 gi|4557753 midline 1 [Homo sapiens] 149 8e-36 gi|15451852 midline 1 [Homo sapiens] 149 8e-36 gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 91 3e-18 gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 86 7e-17 gi|89886468 fibronectin type III and SPRY domain containing 1-li... 82 1e-15 gi|223718222 fibronectin type III and SPRY domain containing 1-l... 82 1e-15 gi|124487387 ring finger protein 207 [Homo sapiens] 81 3e-15 gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 76 9e-14 gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 75 2e-13 gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 70 5e-12 gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 70 5e-12 gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 70 5e-12 gi|54792146 tripartite motif-containing 47 [Homo sapiens] 69 1e-11 gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] 65 2e-10 gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] 65 2e-10 gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 65 2e-10 gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 63 6e-10 gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 63 6e-10 gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 62 1e-09 gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet... 62 1e-09 gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph... 62 1e-09 gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 60 4e-09 >gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] Length = 550 Score = 1137 bits (2940), Expect = 0.0 Identities = 550/550 (100%), Positives = 550/550 (100%) Query: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60 Query: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV Sbjct: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120 Query: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV Sbjct: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180 Query: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY Sbjct: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240 Query: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN Sbjct: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300 Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360 Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420 Query: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD Sbjct: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480 Query: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGKALQQ 540 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGKALQQ Sbjct: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGKALQQ 540 Query: 541 YPSERELRGI 550 YPSERELRGI Sbjct: 541 YPSERELRGI 550 >gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] Length = 710 Score = 1105 bits (2859), Expect = 0.0 Identities = 534/534 (100%), Positives = 534/534 (100%) Query: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60 Query: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV Sbjct: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120 Query: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV Sbjct: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180 Query: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY Sbjct: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240 Query: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN Sbjct: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300 Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360 Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420 Query: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD Sbjct: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480 Query: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE 534 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE Sbjct: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE 534 >gi|134288906 tripartite motif-containing 67 [Homo sapiens] Length = 783 Score = 692 bits (1785), Expect = 0.0 Identities = 359/616 (58%), Positives = 425/616 (68%), Gaps = 95/616 (15%) Query: 4 MEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESES--PQ------------- 48 MEEELKCPVCGS +REPIILPCSHN+C CAR I VQTP+ E PQ Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60 Query: 49 -------SHRAA------GSGVSDYDYLD---------LDKMSLYSEADSGYGSYGGFAS 86 H AA G+G S L DK+SLYSE DSGYGSY Sbjct: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSY----- 115 Query: 87 APTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV-----PRNSCITCPQCHRSLILDDRG 141 TP KSPNGVRV P PP + + A +S ITCPQCHRS LD RG Sbjct: 116 ---TPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRG 172 Query: 142 LRGFPKNRVLEGVIDRYQQSK---------AAALKCQLCEKAPKE-ATVMCEQCDVFYCD 191 LRGF +NR+LE ++ RYQQ + AA CQLC++ P E A +CEQCDV YC Sbjct: 173 LRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCS 232 Query: 192 PCRLRCHPPRGPLAKHRLVPP-----------------AQGRVSRR-------------- 220 C+L+CHP RGP AKHRLV P AQG S Sbjct: 233 ACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGAT 292 Query: 221 --LSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLS 278 + RK TC +HE+EN+SMYCV C+ PVCY CLEEG+H+ HEVK LGAMWK HK+QLS Sbjct: 293 GGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLS 352 Query: 279 QALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARV 338 QALNG+SD+AKEAKEFLVQL+N++QQIQEN +++EACLVAQCDAL+DAL R+KA+LL +V Sbjct: 353 QALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKV 412 Query: 339 NKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTED 398 KE EHKLK+V DQI+HCT+KLRQ+TGLMEYCLEVIKENDPSGFLQISDALI+RV ++++ Sbjct: 413 TKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQE 472 Query: 399 QWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSA 458 QW KG L P+++ +FDL+LD+ PLLQ+IHQLDF+Q+K VP P+LQLE+CCT NNS Sbjct: 473 QWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCR--VPPVPLLQLEKCCTRNNSV 530 Query: 459 TLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNK 518 TL+W+ PP + P DGYILELDDG GGQFREVYVGKET+CT+DGLHFNSTYNARVKAFN Sbjct: 531 TLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNS 590 Query: 519 TGVSPYSKTLVLQTSE 534 +GV PYSKT+VLQTS+ Sbjct: 591 SGVGPYSKTVVLQTSD 606 >gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] Length = 728 Score = 190 bits (482), Expect = 3e-48 Identities = 142/542 (26%), Positives = 245/542 (45%), Gaps = 68/542 (12%) Query: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60 ++ +E EL CP C + P+ILPC H++C C + +L+ Sbjct: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTL------------------- 64 Query: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPAL--- 117 D + G S ++P + P+ P+M P Sbjct: 65 --------------DDSFNDVGSDNSNQSSPRLRLPS------PSMDKIDRINRPGWKRN 104 Query: 118 APVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK--AAALKCQLCEKAP 175 + PR + CP C + L +RG+ G +N LE +++RY+Q+ A A+ C LC+ P Sbjct: 105 SLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPP 164 Query: 176 KEATVMCEQCDVFYCDPCRLRCHPPRGPL-AKHRLVPPAQGRVSRRLSPRKVSTCTDHEL 234 +E+T C C YC+ C + H P G + A+H V P + P K+ C +HE Sbjct: 165 QESTKSCMDCSASYCNEC-FKIHHPWGTIKAQHEYVGP-----TTNFRP-KILMCPEHET 217 Query: 235 ENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEF 294 E +MYC C+ PVC+ C G H++H V + + +K K +LS+ ++ L + + K Sbjct: 218 ERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQ 277 Query: 295 LVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQIS 354 + +L ++++ + N + + + L + L RK+ +L ++ + +L + Q+ Sbjct: 278 ISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQME 337 Query: 355 HCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDF- 413 L + GL+ Y EV+KE D S F+Q + L R+ + + P T F Sbjct: 338 EYQ-GLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATE--SLKSFRPAAQTSFE 394 Query: 414 DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPAD 473 D ++ S + + +L F SS + P + E+ +NN A ++W P AD Sbjct: 395 DYVVNTSKQTELLGELSFF----SSGID-VPEINEEQSKVYNN-ALINWHHPEKD--KAD 446 Query: 474 GYILE---LDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVL 530 Y+LE ++ + + E+ V T + L +STY RV+A+ + SP S+ L+L Sbjct: 447 SYVLEYRKINRDDEMSWNEIEV-CGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELIL 505 Query: 531 QT 532 T Sbjct: 506 HT 507 >gi|47174859 tripartite motif-containing 46 [Homo sapiens] Length = 759 Score = 171 bits (434), Expect = 1e-42 Identities = 156/573 (27%), Positives = 243/573 (42%), Gaps = 86/573 (15%) Query: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQ--------TPESE------- 45 M+ ME+EL CPVC Y++P++LPC+HN+CQACAR +L Q P SE Sbjct: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83 Query: 46 -SPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPP 104 S +S R + + D LD SG+G+Y G P V +FP Sbjct: 84 PSTRSPRLSRRTLPKPDRLD-------RLLKSGFGTYPGRKRGALHP------QVIMFP- 129 Query: 105 AMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKA- 163 CP C + L +RGL G +N LE V++RY+QS + Sbjct: 130 -----------------------CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV 166 Query: 164 -AALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLS 222 A+ CQLC+ P EAT C +C +C+ C HP A+H P LS Sbjct: 167 GGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPT-------LS 219 Query: 223 PR-KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQAL 281 R K C DH+ E + YC C+ VC C HS H++ + + ++ K +L+++L Sbjct: 220 FRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSL 278 Query: 282 NGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKE 341 + + + +L V+ + + + + + L L ++A LL + + Sbjct: 279 TYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEEC 338 Query: 342 HEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWG 401 + +L + QI L +GL+ Y EV+KE D F+Q + L R+ + Sbjct: 339 QQERLARLSAQIQEHR-SLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--A 395 Query: 402 KGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 T P ++ F LD ++ + +L+F++ VP P++ + + + L Sbjct: 396 LQTFRPAASSSFRHCQLDVGREMKLLTELNFLR------VPEAPVIDTQRTFAY-DQIFL 448 Query: 461 SWKQPPLSTVPADGYILEL--------DDGNGGQFREVYVGKETMCTVDGLHFNSTYNAR 512 W+ PP S PA Y +E Q RE G T ++ S Y R Sbjct: 449 CWRLPPHSP-PAWHYTVEFRRTDVPAQPGPTRWQRREEVRG--TSALLENPDTGSVYVLR 505 Query: 513 VKAFNKTGVSPYSKTLVLQTSEGKALQQYPSER 545 V+ NK G YS+ + L T L + R Sbjct: 506 VRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSR 538 >gi|223890259 midline 2 isoform 2 [Homo sapiens] Length = 705 Score = 163 bits (413), Expect = 3e-40 Identities = 120/459 (26%), Positives = 201/459 (43%), Gaps = 54/459 (11%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165 CP C + L+ RGL G +N L+ +IDR+Q++ + Sbjct: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135 Query: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223 + CQ CE+ P++A C C+V YCD C HP + P HRLV P R + Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193 Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283 TC DHE E +MYCV +C C G+H H+V +L ++ K L L Sbjct: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249 Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343 L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ + Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309 Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403 KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV + Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367 Query: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 L P + + + +LD S + + LD++ P P ++ E C +++ T+ Sbjct: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421 Query: 461 SWKQPPLSTVPADGYILELDDGNG-GQFREVYVG----------KETMCTVDGLHFNSTY 509 W ++ Y L+ G F +Y K+ TV GL + Y Sbjct: 422 HWISDDEFSI--SSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479 Query: 510 NARVKAFNKTGVSPYSKTLVLQTSEGKALQQYPSERELR 548 VKA N+ G T + S+ L + ++L+ Sbjct: 480 IFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLK 518 >gi|223890257 midline 2 isoform 1 [Homo sapiens] Length = 735 Score = 159 bits (403), Expect = 5e-39 Identities = 100/362 (27%), Positives = 168/362 (46%), Gaps = 41/362 (11%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165 CP C + L+ RGL G +N L+ +IDR+Q++ + Sbjct: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135 Query: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223 + CQ CE+ P++A C C+V YCD C HP + P HRLV P R + Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193 Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283 TC DHE E +MYCV +C C G+H H+V +L ++ K L L Sbjct: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249 Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343 L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ + Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309 Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403 KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV + Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367 Query: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 L P + + + +LD S + + LD++ P P ++ E C +++ T+ Sbjct: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421 Query: 461 SW 462 W Sbjct: 422 HW 423 >gi|148833499 midline 1 [Homo sapiens] Length = 667 Score = 149 bits (375), Expect = 8e-36 Identities = 113/429 (26%), Positives = 182/429 (42%), Gaps = 50/429 (11%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164 CP C + L RGL G +N L+ +IDR+Q++ A Sbjct: 56 CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115 Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223 + CQ C++ P ++A C C+V YCD C HP + P HRL+ P R L Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174 Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283 C +HE E +MYCV +C C G+H H+V AL + K L L Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229 Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343 L R E + L +L Q ++ N+ EA L +CD LI+ + +R+ + ++ + Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289 Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403 +L+ + QI++C + ++ L+ +KEND + FLQ + + RV + Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347 Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 L P + + FD +LD S + + LD++ P P ++ E C ++ T+ Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401 Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511 W +V + + G + + V K+ TV GL + Y Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461 Query: 512 RVKAFNKTG 520 VKA N+ G Sbjct: 462 MVKAINQAG 470 >gi|4557753 midline 1 [Homo sapiens] Length = 667 Score = 149 bits (375), Expect = 8e-36 Identities = 113/429 (26%), Positives = 182/429 (42%), Gaps = 50/429 (11%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164 CP C + L RGL G +N L+ +IDR+Q++ A Sbjct: 56 CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115 Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223 + CQ C++ P ++A C C+V YCD C HP + P HRL+ P R L Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174 Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283 C +HE E +MYCV +C C G+H H+V AL + K L L Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229 Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343 L R E + L +L Q ++ N+ EA L +CD LI+ + +R+ + ++ + Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289 Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403 +L+ + QI++C + ++ L+ +KEND + FLQ + + RV + Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347 Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 L P + + FD +LD S + + LD++ P P ++ E C ++ T+ Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401 Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511 W +V + + G + + V K+ TV GL + Y Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461 Query: 512 RVKAFNKTG 520 VKA N+ G Sbjct: 462 MVKAINQAG 470 >gi|15451852 midline 1 [Homo sapiens] Length = 667 Score = 149 bits (375), Expect = 8e-36 Identities = 113/429 (26%), Positives = 182/429 (42%), Gaps = 50/429 (11%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164 CP C + L RGL G +N L+ +IDR+Q++ A Sbjct: 56 CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115 Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223 + CQ C++ P ++A C C+V YCD C HP + P HRL+ P R L Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174 Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283 C +HE E +MYCV +C C G+H H+V AL + K L L Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229 Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343 L R E + L +L Q ++ N+ EA L +CD LI+ + +R+ + ++ + Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289 Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403 +L+ + QI++C + ++ L+ +KEND + FLQ + + RV + Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347 Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460 L P + + FD +LD S + + LD++ P P ++ E C ++ T+ Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401 Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511 W +V + + G + + V K+ TV GL + Y Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461 Query: 512 RVKAFNKTG 520 VKA N+ G Sbjct: 462 MVKAINQAG 470 >gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] Length = 358 Score = 90.9 bits (224), Expect = 3e-18 Identities = 64/266 (24%), Positives = 110/266 (41%), Gaps = 53/266 (19%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDV 187 CP C ++LD G+ G +N ++E +ID Y+Q + Sbjct: 78 CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSR----------------------- 114 Query: 188 FYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMP 247 P + + L C +HE E ++YC+ C++P Sbjct: 115 ------------------------PLHSKAEQHLM------CEEHEEEKINIYCLSCEVP 144 Query: 248 VCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQE 307 C C G H EV L ++K KS+LS + L + + Q+ + Q I++ Sbjct: 145 TCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIED 204 Query: 308 NSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLM 367 NS + L + ++L L RK +LL + +E E KL+ VR I L ++ L+ Sbjct: 205 NSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLV 264 Query: 368 EYCLEVIKENDPSGFLQISDALIRRV 393 E ++ ++E + +LQ + LI +V Sbjct: 265 ESAIQSMEEPQMALYLQQAKELINKV 290 Score = 47.4 bits (111), Expect = 3e-05 Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 M+ +E++L CP+C + +P+ ILPC HNLC+ CA ++ Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDV 54 >gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] Length = 353 Score = 86.3 bits (212), Expect = 7e-17 Identities = 61/266 (22%), Positives = 113/266 (42%), Gaps = 54/266 (20%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDV 187 CP C +I+D G+ G +N ++E +ID Y+ ++C Sbjct: 75 CPTCRHEVIMDRHGVYGLQRNLLVENIIDIYK-----------------------QECS- 110 Query: 188 FYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMP 247 SR L C +HE E ++YC+ C++P Sbjct: 111 ------------------------------SRPLQKGSHPMCKEHEDEKINIYCLTCEVP 140 Query: 248 VCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQE 307 C C G H + EV L ++++ K++L+ ++ L + + QL + + +E Sbjct: 141 TCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKE 200 Query: 308 NSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLM 367 NS + + L + D L L+ +K++LL R+ +E E KL + I +L ++T L+ Sbjct: 201 NSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLV 260 Query: 368 EYCLEVIKENDPSGFLQISDALIRRV 393 E ++ + E + FL + LI+ + Sbjct: 261 ETAIQSLDEPGGATFLLTAKQLIKSI 286 Score = 48.9 bits (115), Expect = 1e-05 Identities = 19/38 (50%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 ME +E++L CP+C + +P+ ILPC HNLC+ CA +I Sbjct: 14 MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDI 51 >gi|89886468 fibronectin type III and SPRY domain containing 1-like isoform 1 [Homo sapiens] Length = 498 Score = 82.4 bits (202), Expect = 1e-15 Identities = 72/270 (26%), Positives = 123/270 (45%), Gaps = 20/270 (7%) Query: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333 K L + ++ L+++ E + F+ L + ++ +QENS + L + D+L L+ K Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64 Query: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 ++ + +E K + ++ QIS C L + L+E+ + +P F + + + RV Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124 Query: 394 HLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECC 452 T + +L P+++ + L +D S Q + L F+ PVP P + EC Sbjct: 125 --TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVECL 176 Query: 453 THNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVDGL 503 +NS T++W+ P D +ILE N V K T T+ GL Sbjct: 177 VADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGL 235 Query: 504 HFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532 F+S Y N RV+A NK YS + L+T Sbjct: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLET 265 >gi|223718222 fibronectin type III and SPRY domain containing 1-like isoform 3 [Homo sapiens] Length = 530 Score = 82.4 bits (202), Expect = 1e-15 Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 20/272 (7%) Query: 272 LHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRK 331 L + L + ++ L+++ E + F+ L + ++ +QENS + L + D+L L+ K Sbjct: 35 LQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVK 94 Query: 332 AQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIR 391 ++ + +E K + ++ QIS C L + L+E+ + +P F + + + Sbjct: 95 ESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKD 154 Query: 392 RVHLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEE 450 RV T + +L P+++ + L +D S Q + L F+ PVP P + E Sbjct: 155 RV--TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVE 206 Query: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVD 501 C +NS T++W+ P D +ILE N V K T T+ Sbjct: 207 CLVADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLS 265 Query: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532 GL F+S Y N RV+A NK YS + L+T Sbjct: 266 GLKFDSKYMNFRVRACNKAVAGEYSDPVTLET 297 >gi|124487387 ring finger protein 207 [Homo sapiens] Length = 634 Score = 80.9 bits (198), Expect = 3e-15 Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 15/273 (5%) Query: 126 ITCPQCHRSLILDDRGLRGFPK-NRVLEGVIDRYQQSKAAA--LKCQL-CEKAPKEATVM 181 +TCP C +L +G G P +R+L+ ++D A C L C + E T Sbjct: 58 LTCPLCQHQTVL--KGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYF 115 Query: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241 C C C CR H R A+H +V A G+ SR + P+K CT H E + ++ Sbjct: 116 CNTCGQPLCARCRDETHRAR-MFARHDIV--ALGQRSRDV-PQK---CTLHA-EPYLLFS 167 Query: 242 VQCKMPVCYQCLEE-GKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300 K+ +C +C + K S L + + +L QA+ + +E + L+ Sbjct: 168 TDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQA 227 Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360 MV++++ ++ E E + A ++ D L RKA LL V ++E K K ++Q+SH L Sbjct: 228 MVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLL 287 Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 + C + + + FL + L+ R+ Sbjct: 288 PTLQVHLVICSSFLSLANKAEFLDLGYELMERL 320 Score = 33.9 bits (76), Expect = 0.40 Identities = 12/28 (42%), Positives = 15/28 (53%) Query: 8 LKCPVCGSFYREPIILPCSHNLCQACAR 35 L CP+C Y P +L C H+ C C R Sbjct: 23 LVCPLCHVQYERPCLLDCFHDFCAGCLR 50 >gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo sapiens] Length = 496 Score = 75.9 bits (185), Expect = 9e-14 Identities = 67/272 (24%), Positives = 123/272 (45%), Gaps = 24/272 (8%) Query: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333 + L + + L+ + +E + F+ L+ M+ ++ NS + + L A+ +L L K Sbjct: 5 REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64 Query: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 +L ++ ++ + +++Q++ CT L + L+E + ++ D F Q + + V Sbjct: 65 MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124 Query: 394 HLTEDQWGKGTLTP--RMTTDFDLSLDNSPLLQSIHQ-LDFVQVKASSPVPATPILQLEE 450 T+ P R++ +S + S L+ Q +Q PVP+ P++ L E Sbjct: 125 ----------TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAE 174 Query: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGN--------GGQFREVYVG-KETMCTVD 501 +N TL W+ P + D Y+LE N Q V G ++T T+ Sbjct: 175 SLVADNCVTLVWRMPDEDS-KIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233 Query: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532 GL F+ Y N RVKA NK +S+ + L+T Sbjct: 234 GLKFDMKYMNFRVKACNKAVAGEFSEPVTLET 265 >gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] Length = 400 Score = 74.7 bits (182), Expect = 2e-13 Identities = 64/272 (23%), Positives = 115/272 (42%), Gaps = 23/272 (8%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ-----LCEKAPKE-ATVM 181 CP C ++LD G+ G +N ++E +ID Y+Q + L + +CE+ +E + Sbjct: 78 CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINIY 137 Query: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241 C C+V C C++ +A + Q + L PR Sbjct: 138 CLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR----------------- 180 Query: 242 VQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNM 301 ++C C + SS K+ S+LS + L + + Q+ + Sbjct: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240 Query: 302 VQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLR 361 Q I++NS + L + ++L L RK +LL + +E E KL+ VR I L Sbjct: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300 Query: 362 QTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 ++ L+E ++ ++E + +LQ + LI +V Sbjct: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKV 332 Score = 47.4 bits (111), Expect = 3e-05 Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 M+ +E++L CP+C + +P+ ILPC HNLC+ CA ++ Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDV 54 >gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] Length = 452 Score = 70.1 bits (170), Expect = 5e-12 Identities = 43/165 (26%), Positives = 81/165 (49%) Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288 C +HE E ++YC+ C++P C C G H +V L +++ KS+LS + L Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183 Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348 + + QL + + I+E + + L + D L L RK ++ + + E KL+ Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243 Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 VR I + L + L+E ++ + E + + FLQ + L++++ Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288 Score = 47.4 bits (111), Expect = 3e-05 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 M+ +E++L CP+C + +P+ ILPC HNLC+ CA +I Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54 Score = 46.2 bits (108), Expect = 8e-05 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183 CP C ++LD G+ G +N ++E +ID Y+Q K +CE+ +E + C Sbjct: 78 CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137 Query: 184 QCDVFYCDPCRL 195 C+V C C++ Sbjct: 138 NCEVPTCSLCKV 149 >gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] Length = 548 Score = 70.1 bits (170), Expect = 5e-12 Identities = 43/165 (26%), Positives = 81/165 (49%) Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288 C +HE E ++YC+ C++P C C G H +V L +++ KS+LS + L Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183 Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348 + + QL + + I+E + + L + D L L RK ++ + + E KL+ Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243 Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 VR I + L + L+E ++ + E + + FLQ + L++++ Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288 Score = 47.4 bits (111), Expect = 3e-05 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 M+ +E++L CP+C + +P+ ILPC HNLC+ CA +I Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54 Score = 46.2 bits (108), Expect = 8e-05 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183 CP C ++LD G+ G +N ++E +ID Y+Q K +CE+ +E + C Sbjct: 78 CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137 Query: 184 QCDVFYCDPCRL 195 C+V C C++ Sbjct: 138 NCEVPTCSLCKV 149 >gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] Length = 540 Score = 70.1 bits (170), Expect = 5e-12 Identities = 43/165 (26%), Positives = 81/165 (49%) Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288 C +HE E ++YC+ C++P C C G H +V L +++ KS+LS + L Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183 Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348 + + QL + + I+E + + L + D L L RK ++ + + E KL+ Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243 Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393 VR I + L + L+E ++ + E + + FLQ + L++++ Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288 Score = 47.4 bits (111), Expect = 3e-05 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%) Query: 1 MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37 M+ +E++L CP+C + +P+ ILPC HNLC+ CA +I Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54 Score = 46.2 bits (108), Expect = 8e-05 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%) Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183 CP C ++LD G+ G +N ++E +ID Y+Q K +CE+ +E + C Sbjct: 78 CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137 Query: 184 QCDVFYCDPCRL 195 C+V C C++ Sbjct: 138 NCEVPTCSLCKV 149 >gi|54792146 tripartite motif-containing 47 [Homo sapiens] Length = 638 Score = 68.9 bits (167), Expect = 1e-11 Identities = 108/424 (25%), Positives = 151/424 (35%), Gaps = 102/424 (24%) Query: 10 CPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMS 69 CP+C REP+ LPC HN C AC + HR A Sbjct: 9 CPICLEPLREPVTLPCGHNFCLACLGALW----------PHRGA---------------- 42 Query: 70 LYSEADSGYGSYGGFASAPTTPCQKS-PNGVRVF----------------PPAMPPPATH 112 SG G GG A P CQ+ P+G+++ P + P PA Sbjct: 43 ------SGAGGPGGAARCPL--CQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPA 94 Query: 113 LSP------ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAAL 166 L+P AL VP S P+ +P + Sbjct: 95 LAPEPSAPSALPSVPEPSAPCAPE-------------PWPAGE--------------EPV 127 Query: 167 KCQLC-EKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRK 225 +C C E A A + C C +C P L H L HRLVPP + R+ L PR Sbjct: 128 RCDACPEGAALPAALSCLSCLASFC-PAHLGPHERSPALRGHRLVPPLR-RLEESLCPR- 184 Query: 226 VSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLS 285 L YC ++ +C C + +H HE+ L L +++ S+ L+ + Sbjct: 185 -------HLRPLERYCRAERVCLCEACAAQ-EHRGHELVPLEQERALQEAEQSKVLSAVE 236 Query: 286 DRAKEAKEFLVQLRNMVQQIQENSV-EFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344 DR E + Q R V I+ +V E E DA AL + Q+L + + Sbjct: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAA-ALQGFQTQVLGFIEEGEAA 295 Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404 L + + + R L + E D FLQ + L R+ L ED G G Sbjct: 296 MLGRSQGDLRR-QEEQRSRLSRARQNLSQVPEADSVSFLQ--ELLALRLAL-EDGCGPGP 351 Query: 405 LTPR 408 PR Sbjct: 352 GPPR 355 >gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] Length = 964 Score = 65.1 bits (157), Expect = 2e-10 Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 36/236 (15%) Query: 160 QSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPC--------RLRCHPPRGPLAKHRLVP 211 +S A +C +C + ++A +C C C C R +C R PL LV Sbjct: 7 ESIAEVFRCFICMEKLRDAR-LCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65 Query: 212 PAQGR-VSRRLSPRKVSTCTDHE------LENH----SMYCVQCKMPVCYQC-LEEGKHS 259 V+++L ++ + T HE ENH S++C CK +C+QC L G H Sbjct: 66 CRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHG 125 Query: 260 SHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQ 319 H K L +++ H +++++ + L R L++L ++VQ+++ N EA A+ Sbjct: 126 GHTFKPLAEIYEQHVTKVNEEVAKLRRR-------LMELISLVQEVERN---VEAVRNAK 175 Query: 320 CDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIK 375 D + + ++AR++ + ++KL + Q L Q T L+E L+ ++ Sbjct: 176 -DERVREIRNAVEMMIARLDTQLKNKLITLMGQ----KTSLTQETELLESLLQEVE 226 >gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] Length = 964 Score = 65.1 bits (157), Expect = 2e-10 Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 36/236 (15%) Query: 160 QSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPC--------RLRCHPPRGPLAKHRLVP 211 +S A +C +C + ++A +C C C C R +C R PL LV Sbjct: 7 ESIAEVFRCFICMEKLRDAR-LCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65 Query: 212 PAQGR-VSRRLSPRKVSTCTDHE------LENH----SMYCVQCKMPVCYQC-LEEGKHS 259 V+++L ++ + T HE ENH S++C CK +C+QC L G H Sbjct: 66 CRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHG 125 Query: 260 SHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQ 319 H K L +++ H +++++ + L R L++L ++VQ+++ N EA A+ Sbjct: 126 GHTFKPLAEIYEQHVTKVNEEVAKLRRR-------LMELISLVQEVERN---VEAVRNAK 175 Query: 320 CDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIK 375 D + + ++AR++ + ++KL + Q L Q T L+E L+ ++ Sbjct: 176 -DERVREIRNAVEMMIARLDTQLKNKLITLMGQ----KTSLTQETELLESLLQEVE 226 >gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo sapiens] Length = 749 Score = 65.1 bits (157), Expect = 2e-10 Identities = 75/313 (23%), Positives = 133/313 (42%), Gaps = 24/313 (7%) Query: 231 DHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKE 290 + E E ++CV CK P+ +H HEV L + K ++ + + L + E Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229 Query: 291 AKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVR 350 + F L + ++EN + E + + +++ L ++ + + + ++ + KL+ + Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289 Query: 351 DQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMT 410 Q+ C L LME E+ E + F++ + A+ D+ GK T Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMA-------DRLGKFLKTK--- 338 Query: 411 TDFDLSLDNSPLLQSIHQLDFVQVKASS---PVPATPIL--QLEECCTHNNSATLSWKQP 465 TD ++S Q++ D Q+ S P P+ P++ Q+ T +S + W Sbjct: 339 TDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSAT-GSSVRVCWSLY 397 Query: 466 PLSTVPADGYILE---LDDGNGG--QFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTG 520 TV + Y L + D + G Q KET C+V L N+ Y V A N+ G Sbjct: 398 SDDTV--ESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAG 455 Query: 521 VSPYSKTLVLQTS 533 SP S+ V T+ Sbjct: 456 PSPSSERAVYMTA 468 >gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] Length = 744 Score = 63.2 bits (152), Expect = 6e-10 Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 3/205 (1%) Query: 225 KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGL 284 K +C +H+ YC C+ +C +C E G+H+ H L + + HK+ L L+ + Sbjct: 114 KPLSCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAV 172 Query: 285 SDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344 + R E L + ++ Q+ + + D L LN RK+ LL + + Sbjct: 173 NKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGL 232 Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404 K KV++ Q+ + + + + L + + +++ DQ Sbjct: 233 KHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFP 290 Query: 405 LTPRMTTDFDLSLDNSPLLQSIHQL 429 L PR D ++ L +SIH L Sbjct: 291 LHPRENDQLDFIVETEGLKKSIHNL 315 Score = 36.2 bits (82), Expect = 0.080 Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 8 LKCPVCGSFYREPIILPCSHNLCQACARNIL 38 L C +C Y+ P +LPC H C+ C +N + Sbjct: 21 LICSICLERYKNPKVLPCLHTFCERCLQNYI 51 >gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] Length = 771 Score = 63.2 bits (152), Expect = 6e-10 Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 3/205 (1%) Query: 225 KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGL 284 K +C +H+ YC C+ +C +C E G+H+ H L + + HK+ L L+ + Sbjct: 141 KPLSCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAV 199 Query: 285 SDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344 + R E L + ++ Q+ + + D L LN RK+ LL + + Sbjct: 200 NKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGL 259 Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404 K KV++ Q+ + + + + L + + +++ DQ Sbjct: 260 KHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFP 317 Query: 405 LTPRMTTDFDLSLDNSPLLQSIHQL 429 L PR D ++ L +SIH L Sbjct: 318 LHPRENDQLDFIVETEGLKKSIHNL 342 Score = 36.2 bits (82), Expect = 0.080 Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 8 LKCPVCGSFYREPIILPCSHNLCQACARNIL 38 L C +C Y+ P +LPC H C+ C +N + Sbjct: 48 LICSICLERYKNPKVLPCLHTFCERCLQNYI 78 >gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma [Homo sapiens] Length = 546 Score = 62.4 bits (150), Expect = 1e-09 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%) Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170 I CP + L D G+ G KN L +++R Q S + ++C Sbjct: 70 IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128 Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230 E A+V C C C C H + LAKHR VP A P + + C+ Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179 Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286 H++ C+ Q +C C E GKH H+ L ++ + + + Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239 Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327 +E ++ +L +VQ I+ E VE +C+ A L + L Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299 Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378 R++ L+ V+ KL +R Q T+ L + + +C + ++++D Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350 >gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta [Homo sapiens] Length = 569 Score = 62.4 bits (150), Expect = 1e-09 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%) Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170 I CP + L D G+ G KN L +++R Q S + ++C Sbjct: 70 IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128 Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230 E A+V C C C C H + LAKHR VP A P + + C+ Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179 Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286 H++ C+ Q +C C E GKH H+ L ++ + + + Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239 Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327 +E ++ +L +VQ I+ E VE +C+ A L + L Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299 Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378 R++ L+ V+ KL +R Q T+ L + + +C + ++++D Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350 >gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha [Homo sapiens] Length = 574 Score = 62.4 bits (150), Expect = 1e-09 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%) Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170 I CP + L D G+ G KN L +++R Q S + ++C Sbjct: 70 IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128 Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230 E A+V C C C C H + LAKHR VP A P + + C+ Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179 Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286 H++ C+ Q +C C E GKH H+ L ++ + + + Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239 Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327 +E ++ +L +VQ I+ E VE +C+ A L + L Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299 Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378 R++ L+ V+ KL +R Q T+ L + + +C + ++++D Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350 >gi|62241003 cardiomyopathy associated 5 [Homo sapiens] Length = 4069 Score = 60.5 bits (145), Expect = 4e-09 Identities = 77/329 (23%), Positives = 130/329 (39%), Gaps = 30/329 (9%) Query: 220 RLSPRKVSTCTDHELENHSM--YCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQL 277 +LS V+ EL+ + YC CK P+ G H HEV L K QL Sbjct: 3490 QLSSEVVTEKAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQL 3549 Query: 278 SQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALID---ALNRRKAQL 334 ++ L L +++ + F+ ++ + I+EN + E L Q + ++ A KAQ Sbjct: 3550 AEFLENLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQS 3609 Query: 335 LARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVH 394 V K+ K++ + +Q+ H + +E + +E D + FL + + R+ Sbjct: 3610 FEEVKKK---KMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLL 3666 Query: 395 LTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTH 454 + P + F+ D+S Q+ VP P L+ +E Sbjct: 3667 SAMESTASLEKMPAAFSLFEHYDDSSARSD--------QMLKQVAVPQPPRLEPQE---- 3714 Query: 455 NNSAT-----LSWKQPPLSTVPA-DGYILE--LDDGNGGQFREVY--VGKETMCTVDGLH 504 NSAT + W + + Y +E DD + E Y KE+ C + L Sbjct: 3715 PNSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLE 3774 Query: 505 FNSTYNARVKAFNKTGVSPYSKTLVLQTS 533 + Y V A N TG S S+ + +T+ Sbjct: 3775 PDRCYQVWVMAVNFTGCSLPSERAIFRTA 3803 Score = 37.4 bits (85), Expect = 0.036 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Query: 441 PATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILEL--DDGNGGQFREVYVGKETMC 498 P+TP+++ E+C N+AT+ W+ P + + Y LE G+ + G + + Sbjct: 3804 PSTPVIRAEDCTVCWNTATIRWR--PTTPEATETYTLEYCRQHSPEGEGLRSFSGIKGLQ 3861 Query: 499 TVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQT 532 L N Y V+A N G S S+ ++ T Sbjct: 3862 LKVNLQPNDNYFFYVRAINAFGTSEQSEAALIST 3895 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.133 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,813,869 Number of Sequences: 37866 Number of extensions: 1206882 Number of successful extensions: 6335 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 225 Number of HSP's successfully gapped in prelim test: 155 Number of HSP's that attempted gapping in prelim test: 5440 Number of HSP's gapped (non-prelim): 948 length of query: 550 length of database: 18,247,518 effective HSP length: 107 effective length of query: 443 effective length of database: 14,195,856 effective search space: 6288764208 effective search space used: 6288764208 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.