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Search of human proteins with 164519146
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|164519146 GATA zinc finger domain containing 2A [Homo
sapiens]
(633 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|164519146 GATA zinc finger domain containing 2A [Homo sapiens] 1231 0.0
gi|21218438 GATA zinc finger domain containing 2B [Homo sapiens] 376 e-104
gi|119943102 CREB binding protein isoform b [Homo sapiens] 48 2e-05
gi|119943104 CREB binding protein isoform a [Homo sapiens] 48 2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 2e-04
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 44 5e-04
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 43 8e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 43 0.001
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 42 0.002
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 41 0.003
gi|19924099 synapsin I isoform Ia [Homo sapiens] 41 0.004
gi|150170670 piccolo isoform 2 [Homo sapiens] 41 0.004
gi|150378539 piccolo isoform 1 [Homo sapiens] 41 0.004
gi|19913369 transducin beta-like 3 [Homo sapiens] 41 0.004
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 40 0.005
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 40 0.007
gi|19924097 synapsin I isoform Ib [Homo sapiens] 40 0.007
gi|116284392 mucin 2 precursor [Homo sapiens] 39 0.011
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 39 0.011
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 39 0.011
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 39 0.011
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 39 0.011
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 39 0.011
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 39 0.011
gi|154426272 hypothetical protein LOC54540 [Homo sapiens] 39 0.011
gi|56549694 enabled homolog isoform a [Homo sapiens] 39 0.015
gi|39930375 enabled homolog isoform b [Homo sapiens] 39 0.015
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 39 0.015
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 39 0.015
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.015
>gi|164519146 GATA zinc finger domain containing 2A [Homo sapiens]
Length = 633
Score = 1231 bits (3184), Expect = 0.0
Identities = 633/633 (100%), Positives = 633/633 (100%)
Query: 1 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL 60
MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL
Sbjct: 1 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL 60
Query: 61 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL 120
LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL
Sbjct: 61 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL 120
Query: 121 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 180
TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT
Sbjct: 121 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 180
Query: 181 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS 240
GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS
Sbjct: 181 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS 240
Query: 241 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT 300
QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT
Sbjct: 241 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT 300
Query: 301 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL 360
SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL
Sbjct: 301 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL 360
Query: 361 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQC 420
LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQC
Sbjct: 361 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQC 420
Query: 421 KTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQG 480
KTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQG
Sbjct: 421 KTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQG 480
Query: 481 TAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRG 540
TAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRG
Sbjct: 481 TAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRG 540
Query: 541 VLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPS 600
VLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPS
Sbjct: 541 VLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPS 600
Query: 601 LAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK 633
LAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK
Sbjct: 601 LAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK 633
>gi|21218438 GATA zinc finger domain containing 2B [Homo sapiens]
Length = 593
Score = 376 bits (966), Expect = e-104
Identities = 268/669 (40%), Positives = 357/669 (53%), Gaps = 124/669 (18%)
Query: 1 MTEEACRTRSQKRALERDPTEDDVESKKIKMERG-------LLASDLNTD-GDMRV---- 48
MTE+A R KR+L+ DDV +K++KME +LA D ++ V
Sbjct: 4 MTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHEL 63
Query: 49 -TPEPGAG------PTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSP 101
T + G+G G LR A G+ + D PVDM S+ + R PSP
Sbjct: 64 PTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLTPSP 123
Query: 102 DVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVL 161
D+IVLSDNE SSPR + LK + E EER+++IKQL++ELRLEEA+LVL
Sbjct: 124 DIIVLSDNEA-SSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVL 182
Query: 162 LKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPP 221
LKKLRQSQ+QKE QK P +Q ++ S++ P
Sbjct: 183 LKKLRQSQLQKENVVQKT-------------------------PVVQNAA-----SIVQP 212
Query: 222 PLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPS-VQ 280
GQQ SKL + +Q V P +R Q IR ++T P +L++ R P+ Q
Sbjct: 213 SPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQ 272
Query: 281 IQGQR-IIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQ------ANSTPTSVAS 333
+QGQR + GL+R PN + +N + +S+ TS+ ++ P +V
Sbjct: 273 LQGQRGPPKPGLVRTTT-PNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNR 331
Query: 334 VVTSAESP------ASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYL 387
V + SP A+ QAAAKLALRKQLEKTLLEIPPPKPPAP ++FLPSAAN+EFIY+
Sbjct: 332 VSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYM 391
Query: 388 VGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQK 447
VGLEEVVQ+++++QG+ S A++L EP++CAQC+TDFT W++EK+G I+CE CMT+NQK
Sbjct: 392 VGLEEVVQSVIDSQGK-SCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQK 450
Query: 448 KALKVEHTSRLKAAFVKALQQEQEIEQRLLQQG-----TAPA--QAKAEPTAAPHPVLKQ 500
KALK EHT+RLK AFVKALQQEQEIEQRL QQ TAPA + T H L+Q
Sbjct: 451 KALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQ 510
Query: 501 VIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATAL 560
+P+ S L RG T+ R +L F+ +P+L +
Sbjct: 511 APQPQ----------------------SSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM 548
Query: 561 VSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDM 620
G +A+++ + HK S DRQREYLLDM
Sbjct: 549 -----------------------------PGVNIAYLNTGIGGHKGPSLADRQREYLLDM 579
Query: 621 IPPRSIPQS 629
IPPRSI QS
Sbjct: 580 IPPRSISQS 588
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 48.1 bits (113), Expect = 2e-05
Identities = 70/326 (21%), Positives = 131/326 (40%), Gaps = 51/326 (15%)
Query: 192 PLVRGTQNIPAGKPSLQT--SSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVR 249
P G ++ G+P QT S ++PG+ +P PL + LGPQAS Q+ PP+ +
Sbjct: 762 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPL--------NMLGPQAS-QLPCPPVTQ 812
Query: 250 GAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVN--IP 307
+H PPP A A +PS+Q + P+T + + P
Sbjct: 813 SP--LHPT-------PPPASTA--AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 861
Query: 308 QPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPK 367
PTP S+ T T + + A V ++P + A Q + T + PP
Sbjct: 862 TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVA-TPQSSQQQPTPVHAQPPG 920
Query: 368 PPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREP---YMCAQCKTDF 424
P + +AA+ + N + T +++A S++P + KT+
Sbjct: 921 TPLSQ-----AAAS------------IDNRVPTPSSVASAETNSQQPGPDVPVLEMKTET 963
Query: 425 TCRWREEKSGAIMCE---NCMTTNQKKALKVEHTSRL---KAAFVKALQQEQEIEQRLLQ 478
E G E M + + A +V+ + + K+ ++ +++ E++ + +
Sbjct: 964 QAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKE 1023
Query: 479 QGTAPAQAKAEPTAAPHPVLKQVIKP 504
+ + + A + +P K++ KP
Sbjct: 1024 EEESSSNGTASQSTSPSQPRKKIFKP 1049
Score = 34.3 bits (77), Expect = 0.36
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 112 PSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQ 171
PS ++ AL++ SSP+++++++ LK +L A +K+ +
Sbjct: 2016 PSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA---FIKQRTAKYVA 2072
Query: 172 KEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQAS 231
+ Q G P P + +PSLQ +A G +P P V QQA
Sbjct: 2073 NQPGMQPQPGLQSQPGMQPQPGMHQ-------QPSLQNLNAMQAG--VPRPGVPPQQQAM 2123
Query: 232 SKLGPQASSQVVMPP 246
L PQ + +M P
Sbjct: 2124 GGLNPQGQALNIMNP 2138
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 48.1 bits (113), Expect = 2e-05
Identities = 70/326 (21%), Positives = 131/326 (40%), Gaps = 51/326 (15%)
Query: 192 PLVRGTQNIPAGKPSLQT--SSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVR 249
P G ++ G+P QT S ++PG+ +P PL + LGPQAS Q+ PP+ +
Sbjct: 800 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPL--------NMLGPQAS-QLPCPPVTQ 850
Query: 250 GAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVN--IP 307
+H PPP A A +PS+Q + P+T + + P
Sbjct: 851 SP--LHPT-------PPPASTA--AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 899
Query: 308 QPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPK 367
PTP S+ T T + + A V ++P + A Q + T + PP
Sbjct: 900 TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVA-TPQSSQQQPTPVHAQPPG 958
Query: 368 PPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREP---YMCAQCKTDF 424
P + +AA+ + N + T +++A S++P + KT+
Sbjct: 959 TPLSQ-----AAAS------------IDNRVPTPSSVASAETNSQQPGPDVPVLEMKTET 1001
Query: 425 TCRWREEKSGAIMCE---NCMTTNQKKALKVEHTSRL---KAAFVKALQQEQEIEQRLLQ 478
E G E M + + A +V+ + + K+ ++ +++ E++ + +
Sbjct: 1002 QAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKE 1061
Query: 479 QGTAPAQAKAEPTAAPHPVLKQVIKP 504
+ + + A + +P K++ KP
Sbjct: 1062 EEESSSNGTASQSTSPSQPRKKIFKP 1087
Score = 34.3 bits (77), Expect = 0.36
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 112 PSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQ 171
PS ++ AL++ SSP+++++++ LK +L A +K+ +
Sbjct: 2054 PSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA---FIKQRTAKYVA 2110
Query: 172 KEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQAS 231
+ Q G P P + +PSLQ +A G +P P V QQA
Sbjct: 2111 NQPGMQPQPGLQSQPGMQPQPGMHQ-------QPSLQNLNAMQAG--VPRPGVPPQQQAM 2161
Query: 232 SKLGPQASSQVVMPP 246
L PQ + +M P
Sbjct: 2162 GGLNPQGQALNIMNP 2176
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.4 bits (106), Expect = 2e-04
Identities = 75/288 (26%), Positives = 113/288 (39%), Gaps = 39/288 (13%)
Query: 101 PDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLV 160
P+V V+ D + S+ +G T V K+ + L ++E + Q+ + E
Sbjct: 1664 PEVTVIEDPQ--SNLNDDGFTEVVSKKQQ-KRLQDEERRKKEEQVIQVWNKKNANEKGRS 1720
Query: 161 LLKKLRQSQIQKEATA-QKPTGSVGSTVTTPPPLVRGTQ-NIPAGK---------PSLQT 209
KL +K+AT Q+ S PL T ++PA P +
Sbjct: 1721 QTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAS 1780
Query: 210 SSARMPGSVIPPPLVRGGQQA-SSKLGPQASSQVVMP--PLVRGAQQIHSIRQHSSTGPP 266
+SA +P S + P L +S L P ++S V P A I S +S P
Sbjct: 1781 TSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAP 1840
Query: 267 PLLLAPRASVPSVQIQGQRIIQQGLIRVANVPN-TSLLVNIPQPTPASLKGTTATSAQAN 325
+LA ++ SV I + A++P S L + PTPA + A A
Sbjct: 1841 TPILASVSTPASVTI----------LASASIPILASALASTSAPTPAPAASSPA--APVI 1888
Query: 326 STPTSVASVVTSAE--SPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
+ PT AS T++ +PAS A A T + P P PPAP
Sbjct: 1889 TAPTIPASAPTASVPLAPASASAPAPAP-------TPVSAPNPAPPAP 1929
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 43.9 bits (102), Expect = 5e-04
Identities = 42/184 (22%), Positives = 82/184 (44%), Gaps = 18/184 (9%)
Query: 167 QSQIQKEATAQKPTGSVGSTVTTPPPLVR----GTQNIPAGKPSLQTSSARMPGSVIPPP 222
Q +Q A +P G+ V P V G+Q G+ + ++ + P + +PP
Sbjct: 693 QLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPS 752
Query: 223 LVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSV--Q 280
+++ G SS++ P A + ++ + A + P L++A ++S+ +V Q
Sbjct: 753 VIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSL----------PQQLVIASQSSLLTVPPQ 802
Query: 281 IQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAES 340
QG + QG++ +P S L + + S +T S S PT++ A++
Sbjct: 803 PQGVEPVAQGIVS-QQLPAVSSLPSASSISVTSQVSSTGPSGMP-SAPTNLVPPQNIAQT 860
Query: 341 PASR 344
PA++
Sbjct: 861 PATQ 864
Score = 35.8 bits (81), Expect = 0.12
Identities = 50/205 (24%), Positives = 74/205 (36%), Gaps = 42/205 (20%)
Query: 174 ATAQKPTGS----VGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPP---LVRG 226
A + PTGS +G P + + + +P PS+ A V+PP ++
Sbjct: 719 AVSAVPTGSQIANIGQQANIPTAVQQPSTQVP---PSVIQQGAPPSSQVVPPAQTGIIHQ 775
Query: 227 GQQASSKLGPQA------SSQVVMPPLVRG---------------------AQQIHSIRQ 259
G Q S+ PQ SS + +PP +G A I Q
Sbjct: 776 GVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQ 835
Query: 260 HSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLI--RVANVPNTSLLVNIPQPTPASLKGT 317
SSTGP + AP VP I Q G + V+ P + N+P L
Sbjct: 836 VSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPL--- 892
Query: 318 TATSAQANSTPTSVASVVTSAESPA 342
++T A S ++ S + A A
Sbjct: 893 SSTQFSAQSLAQAIGSQIEDARRAA 917
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 43.1 bits (100), Expect = 8e-04
Identities = 50/213 (23%), Positives = 87/213 (40%), Gaps = 18/213 (8%)
Query: 113 SSPRVNGLTTVALKETSTEALMKSSPEERERM-IKQLKEELRLEEAKLVLLKKLRQSQI- 170
S PR +GL + ++ S E L E R+ + ELR++ L ++ + Q+
Sbjct: 6158 SEPR-SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLV 6216
Query: 171 ------QKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTS----SARMPGSVIP 220
++E K T + T+TT RG + P+ PS S S PG + P
Sbjct: 6217 AAVEVTEQETKVPKKTVIIEETITTVVKSPRGQRRSPSKSPSRSPSRCSASPLRPGLLAP 6276
Query: 221 PPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQ 280
L G + + + V+P L + HS +GP P + +++
Sbjct: 6277 DLLYLPGAGQPRRPEAEPGQKPVVPTLYVTEAEAHSPALPGLSGPQPKWVEVE---ETIE 6333
Query: 281 IQGQRIIQQGLIRVANVPNTSL--LVNIPQPTP 311
++ +++ QG+ VP +S L +P TP
Sbjct: 6334 VRVKKMGPQGVSPTTEVPRSSSGHLFTLPGATP 6366
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 42.7 bits (99), Expect = 0.001
Identities = 114/519 (21%), Positives = 179/519 (34%), Gaps = 70/519 (13%)
Query: 82 PVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTT----------VALKETSTE 131
P R S K+ P P LS QP P V L L++ E
Sbjct: 625 PESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
Query: 132 -ALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKE--ATAQKPTGSVGSTVT 188
A K P+ ++K L E +R EE + + KE A+ Q P + + T
Sbjct: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744
Query: 189 TPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLV 248
T P + T + + P +PPP +K P + Q PP
Sbjct: 745 TAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPP------PPLAKFPPPSQPQPPPPP-- 796
Query: 249 RGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-----IRVANVPNTSLL 303
P LL ASV ++GQ+ +G R +P T
Sbjct: 797 --------------PPSPASLLKSLASV----LEGQKYCYRGTGAAVSTRPGPLPTTQYS 838
Query: 304 VNIPQPTPASLKGTTATSAQANSTPT-SVASVVTSAESPASRQAAAKLALRKQLEKTLLE 362
P A + A SAQ + P+ S +S +++ P +R+ R+ E+ +
Sbjct: 839 PGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARE-------RRAGEEPVPG 891
Query: 363 IPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMS---AATVLSREPYMCAQ 419
P P P ++ P+ + +E L + + L+E GR + A V + EP
Sbjct: 892 PMTPTQPPPPLSLPPARSESE--VLEEISRACETLVERVGRSATDPADPVDTAEPADSGT 949
Query: 420 CKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQ 479
+ + +EE G QK+ K EH +A ++ R ++
Sbjct: 950 ERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQK-EHRRHRRAC--------KDSVGRRPRE 1000
Query: 480 GTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPR 539
G A A+AK P VL + ++ R D + + + + SA P
Sbjct: 1001 GRAKAKAKV-PKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPS 1059
Query: 540 GVLHTFS---PSPKLQNSASATALVSRTGRHSERTVSAG 575
S P K + A VSR R++S G
Sbjct: 1060 AQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEG 1098
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/296 (23%), Positives = 110/296 (37%), Gaps = 72/296 (24%)
Query: 121 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQS------QIQKEA 174
TT K+ S S +R+R + QL R E+ L +L S ++K+A
Sbjct: 219 TTPRKKQNSNSQSTPGSSGQRKRKV-QLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKA 277
Query: 175 TAQ-------KPTGSVGSTVTTPPPLVRG--TQNIPAGKPSLQTSSARMPGS-------- 217
+ Q + + ++VT PP+ + T +PA P+ +S P +
Sbjct: 278 SLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLK 337
Query: 218 ------VIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLA 271
+PP G + L P + + +PPL S +GPP LL +
Sbjct: 338 KMQTPPSLPPCPESAGAATTEALSPPKTPSL-LPPLGL-----------SQSGPPGLLPS 385
Query: 272 PRA-SVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTS 330
P S P + G +P S++ P +L+ TAT QA S P+
Sbjct: 386 PSFDSKPPTTLLGL------------IPAPSMVPATDTKAPPTLQAETATKPQATSAPSP 433
Query: 331 V-------ASVVTSAESPASRQAAAKLALRKQLEKTLLEIPP------PKPPAPEM 373
+ TS SPA+ A++ + K + PP P PP P +
Sbjct: 434 APKQSFLFGTQNTSPSSPAAPAASS----APPMFKPIFTAPPKSEKEGPTPPGPSV 485
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/315 (21%), Positives = 123/315 (39%), Gaps = 37/315 (11%)
Query: 90 SDMKSERRPPSPDVIVLSDNEQPSSP--RVNGLTTVALKETSTEALMKSSPEERERMIKQ 147
+ + S R P+ L+ P S RV+G T+ L + + S+P + ++
Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423
Query: 148 LKE-ELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPS 206
R+ +A L Q Q + + S T P V G+Q++ +G +
Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP--VAGSQSLSSGAVA 2481
Query: 207 LQTSSA-------RMPGSVIP------PPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQ 253
TSSA +P +P PP G QQ S+ Q + + R +
Sbjct: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER------RSSSS 2535
Query: 254 IHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNI------- 306
S SS+ + + S +G + Q + + VP+ +
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Query: 307 PQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPP 366
P+PTPA K +++S+ ++S+ +S +S +S+ S +S +++ + + P P
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----PSP 2651
Query: 367 KPPAPEMNFLPSAAN 381
P P+ LP A+
Sbjct: 2652 AKPGPQA--LPKPAS 2664
Score = 35.0 bits (79), Expect = 0.21
Identities = 62/280 (22%), Positives = 104/280 (37%), Gaps = 32/280 (11%)
Query: 3 EEACRTRSQKRALERDPTEDDVESK-KIKMERGLLASDLNTDGDMRV----------TPE 51
+ +TR+ R R + +V+SK ++ R S R +PE
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE 1623
Query: 52 PGAGPTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSH-----SDMKSERRPPSPDVIVL 106
P A + L R + + + + GRG G + H + + R P P
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
Query: 107 SDNEQPSSPRVNGLTTVA-LKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKL 165
+ + SS LT A L S A SSPE R R + + + + +K
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSA--SSSPETRSRTPPRHRRSPSVSSPEPA--EKS 1739
Query: 166 RQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVR 225
R S+ ++ A++ + T + +P P RG Q + +T + R
Sbjct: 1740 RSSRRRRSASSPR-TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDR-------S 1791
Query: 226 GGQQASSKLGPQASSQVVMPPLVRGAQQIHS---IRQHSS 262
G Q++S+ ++ S+ + RG HS RQ SS
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 40.8 bits (94), Expect = 0.004
Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 26/205 (12%)
Query: 190 PPPLVRGTQNI-----PAGKPSLQ-----TSSARMPGSVIPPPLVRGGQQASSKLG---- 235
PPP +G Q++ PAG P Q TS+ + P S PP G+Q+ G
Sbjct: 485 PPP--QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
Query: 236 PQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRAS-VPSVQIQGQRIIQQGLIRV 294
P A+ P R A + RQ S +GP P P+AS P Q Q Q+
Sbjct: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAP----PKASGAPPGGQQRQGPPQKPPGPA 598
Query: 295 ANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRK 354
S +P+ P + + + P + S + P AAA
Sbjct: 599 GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
Query: 355 QLEKT-----LLEIPPPKPPAPEMN 374
QL K+ +P P PP P ++
Sbjct: 659 QLNKSQSLTNAFNLPEPAPPRPSLS 683
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/202 (26%), Positives = 76/202 (37%), Gaps = 25/202 (12%)
Query: 166 RQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVR 225
+Q +Q A A PT + V P P Q GK S Q + P S +P P
Sbjct: 423 QQPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP--- 476
Query: 226 GGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQR 285
+K PQ PP G+ + S +Q ST PPP P + PS Q
Sbjct: 477 ------AKPPPQQPGPAKPPPQQPGSAKPPS-QQPGSTKPPP--QQPGPAKPSPQ----- 522
Query: 286 IIQQGLIRVANVPNTSLLVNIPQPTPA---SLKGTTATSAQANSTPTSVASVVTSAESPA 342
Q G + + S + QP+PA + + T S + P +V SA+ P
Sbjct: 523 --QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Query: 343 SRQAAAKLALRKQLEKTLLEIP 364
S+ + + LL +P
Sbjct: 581 SQGLPKTICPLCNTTELLLHVP 602
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/201 (25%), Positives = 75/201 (37%), Gaps = 27/201 (13%)
Query: 190 PPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRG-----GQQASSKLGPQASSQVVM 244
PPP G P +P ++ PGS PPP G QQ S P
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 245 P------PLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVP 298
P P AQQ S + S TG L P S PS + + + + + + N
Sbjct: 539 PSAQQPSPAKPSAQQ--STKPVSQTGSGKPLQPPTVS-PSAKQPPSQGLPKTICPLCN-- 593
Query: 299 NTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEK 358
T LL+++P+ T T Q T+V S+ +P + L L Q+++
Sbjct: 594 TTELLLHVPE----KANFNTCTECQ-----TTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644
Query: 359 TLLE--IPPPKPPAPEMNFLP 377
L P P P P++ P
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAP 665
Score = 32.7 bits (73), Expect = 1.0
Identities = 50/199 (25%), Positives = 70/199 (35%), Gaps = 30/199 (15%)
Query: 185 STVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKL-GPQASSQVV 243
S +T P GT P P A+ G PP G ++ SS+ GP+A +Q
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQ-- 393
Query: 244 MPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRII--QQGLIRVANVPN-T 300
PP G P A P+ Q+ + + Q GL A P T
Sbjct: 394 -PP---------------GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437
Query: 301 SLLVNIPQP--TPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKL------AL 352
V P P PA G TSAQ + + A+ P + AK +
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 353 RKQLEKTLLEIPPPKPPAP 371
+ ++ PPP+ P P
Sbjct: 498 KPPSQQPGSTKPPPQQPGP 516
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/202 (26%), Positives = 76/202 (37%), Gaps = 25/202 (12%)
Query: 166 RQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVR 225
+Q +Q A A PT + V P P Q GK S Q + P S +P P
Sbjct: 423 QQPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP--- 476
Query: 226 GGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQR 285
+K PQ PP G+ + S +Q ST PPP P + PS Q
Sbjct: 477 ------AKPPPQQPGPAKPPPQQPGSAKPPS-QQPGSTKPPP--QQPGPAKPSPQ----- 522
Query: 286 IIQQGLIRVANVPNTSLLVNIPQPTPA---SLKGTTATSAQANSTPTSVASVVTSAESPA 342
Q G + + S + QP+PA + + T S + P +V SA+ P
Sbjct: 523 --QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Query: 343 SRQAAAKLALRKQLEKTLLEIP 364
S+ + + LL +P
Sbjct: 581 SQGLPKTICPLCNTTELLLHVP 602
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/201 (25%), Positives = 75/201 (37%), Gaps = 27/201 (13%)
Query: 190 PPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRG-----GQQASSKLGPQASSQVVM 244
PPP G P +P ++ PGS PPP G QQ S P
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 245 P------PLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVP 298
P P AQQ S + S TG L P S PS + + + + + + N
Sbjct: 539 PSAQQPSPAKPSAQQ--STKPVSQTGSGKPLQPPTVS-PSAKQPPSQGLPKTICPLCN-- 593
Query: 299 NTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEK 358
T LL+++P+ T T Q T+V S+ +P + L L Q+++
Sbjct: 594 TTELLLHVPE----KANFNTCTECQ-----TTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644
Query: 359 TLLE--IPPPKPPAPEMNFLP 377
L P P P P++ P
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAP 665
Score = 32.7 bits (73), Expect = 1.0
Identities = 50/199 (25%), Positives = 70/199 (35%), Gaps = 30/199 (15%)
Query: 185 STVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKL-GPQASSQVV 243
S +T P GT P P A+ G PP G ++ SS+ GP+A +Q
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQ-- 393
Query: 244 MPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRII--QQGLIRVANVPN-T 300
PP G P A P+ Q+ + + Q GL A P T
Sbjct: 394 -PP---------------GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437
Query: 301 SLLVNIPQP--TPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKL------AL 352
V P P PA G TSAQ + + A+ P + AK +
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 353 RKQLEKTLLEIPPPKPPAP 371
+ ++ PPP+ P P
Sbjct: 498 KPPSQQPGSTKPPPQQPGP 516
>gi|19913369 transducin beta-like 3 [Homo sapiens]
Length = 808
Score = 40.8 bits (94), Expect = 0.004
Identities = 65/286 (22%), Positives = 112/286 (39%), Gaps = 21/286 (7%)
Query: 289 QGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAA 348
QG +RV + + QP + T T A T+ + +A+ A
Sbjct: 268 QGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAH-----TAGVVLTATADHNLLLYEAR 322
Query: 349 KLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAAT 408
L L+KQ E+ + PE + + A+N+ + + L+ +L + A
Sbjct: 323 SLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLAL 382
Query: 409 VLSREPYMCAQCKTDFTCR-WREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQ 467
+ R+ ++ A C D + R WR K+G +MC + ++ SRLK +F+
Sbjct: 383 DVFRKGWLFASCAKDQSVRIWRMNKAGQVMCV-AQGSGHTHSVGTVCCSRLKESFLVTGS 441
Query: 468 QEQEIE-----QRLLQQGTAP------AQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEAR 516
Q+ ++ + LL + TAP QA+ + I P KL + R
Sbjct: 442 QDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDR 501
Query: 517 DWSNGAVLQASSQLSRGSATTPRGV-LHTFSPSPKLQNSASATALV 561
A+ Q QL + RG+ FSP ++ +ASA +
Sbjct: 502 TAKLWALPQC--QLLGVFSGHRRGLWCVQFSPMDQVLATASADGTI 545
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 40.4 bits (93), Expect = 0.005
Identities = 56/189 (29%), Positives = 72/189 (38%), Gaps = 33/189 (17%)
Query: 196 GTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGP-QASSQVVMPPLVRGAQQI 254
GT N P G QT S S++P P LGP Q S PPL
Sbjct: 1703 GTGN-PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPA---- 1757
Query: 255 HSIRQHSSTGPPP---LLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPT- 310
S GP P L LAP +S S L+ A+V T L P PT
Sbjct: 1758 ------SPVGPAPAHTLTLAPASSSAS------------LLAPASV-QTLTLSPAPVPTL 1798
Query: 311 -PASLKGTTATSAQANSTPTSVASVVTSAE--SPASRQAAAKLALRKQLEKTL-LEIPPP 366
PA+ + A S + +S+V SA +P ++L + K TL L PP
Sbjct: 1799 GPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPP 1858
Query: 367 KPPAPEMNF 375
PP+ +F
Sbjct: 1859 SPPSTATSF 1867
Score = 36.6 bits (83), Expect = 0.072
Identities = 51/249 (20%), Positives = 97/249 (38%), Gaps = 43/249 (17%)
Query: 175 TAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASS-- 232
T++ PT ++ S TPP VR + P G SL PG PP ++
Sbjct: 1096 TSRPPTPTL-SLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATA 1154
Query: 233 -----KLGPQASSQVVMPPLVRG---AQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQ 284
A ++++ P ++ + ++ SI Q +S P+ A + + QIQG
Sbjct: 1155 TTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGN 1214
Query: 285 RI-----------------IQQGLIRVANVPNTSLLVNIP---------QPTPASLKGTT 318
++ +Q+ ++ + + L++ P PTP +
Sbjct: 1215 KLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSV 1274
Query: 319 ATSAQANST--PTSVASVVTSAESP---ASRQAAAKLALRKQLEKTLLEIPPPKP-PAPE 372
S+ ++T PT ++ + + + P + K+ +R+ L +PP P P P
Sbjct: 1275 LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP 1334
Query: 373 MNFLPSAAN 381
+ LP+ N
Sbjct: 1335 SSGLPAVLN 1343
Score = 33.1 bits (74), Expect = 0.80
Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 8/194 (4%)
Query: 185 STVTTPPPLVRGTQNIPAGKP-SLQTSSARMPGSVIPP--PLVRGGQQASSKLGPQASSQ 241
S TT P IP P ++ S + SV PP P+V S L P +S
Sbjct: 1442 SVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPS-LAPSGASP 1500
Query: 242 VVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRAS-VPSVQIQGQRIIQQGLIRVANVPNT 300
L G S+ + G P LLLAP +S VP + L+ + + +
Sbjct: 1501 SASA-LTLGLATAPSLSSSQTPGHP-LLLAPTSSHVPGLNSTVAPACSPVLVPASALASP 1558
Query: 301 SLLVNIPQPTPASLKGTTATSAQANSTPTS-VASVVTSAESPASRQAAAKLALRKQLEKT 359
P P ASL ++++QA +TP + +A+ T+ +P+ A L +
Sbjct: 1559 FPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGA 1618
Query: 360 LLEIPPPKPPAPEM 373
+ + P P M
Sbjct: 1619 APVLASSQTPVPVM 1632
Score = 29.6 bits (65), Expect = 8.8
Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 24/203 (11%)
Query: 179 PTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKL-GPQ 237
P G+ + PP V+ + P K + R P ++G + + GP+
Sbjct: 2841 PENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEA-PSSTLKGKTNGADPVPGPE 2899
Query: 238 A---SSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRV 294
+ V+ P L+ G Q + H P PLL + + + G I
Sbjct: 2900 TLIVADPVLEPQLIPGPQPLGPQPVHR---PNPLLSPVEKRRRGRPPKARDLPIPGTISS 2956
Query: 295 ANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRK 354
A N+ P P P+ L +T + + VT + SP R+
Sbjct: 2957 AGDGNSESRTQ-PPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGR------ 3009
Query: 355 QLEKTLLEIPPPKPPAPEMNFLP 377
PP PP+P + LP
Sbjct: 3010 ---------PPKNPPSPRPSQLP 3023
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 40.0 bits (92), Expect = 0.007
Identities = 63/277 (22%), Positives = 102/277 (36%), Gaps = 34/277 (12%)
Query: 121 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 180
T V L + A + E + + E E + + +Q+ A+ +
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS--RSL 242
Query: 181 GSVGSTVTTPP---PLVRGTQNIPA--GKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG 235
S + +++P P RGT PA +P + A P V PP + A+ LG
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-----KDAAPALG 297
Query: 236 PQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVA 295
P +SS + P Q S PP L P +S + Q+ +
Sbjct: 298 PLSSSPLATPSPSAALQ---------SQAPPTLPATPHSSSLTCQLATPLPLAP---PSP 345
Query: 296 NVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQ 355
+ P + + P TP S T+ S +T + + S S + QA LAL
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP- 404
Query: 356 LEKTLLEIPPPKPPAPEMNFL----PSAANNEFIYLV 388
L+ PP P +P ++ L P A N ++L+
Sbjct: 405 -----LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Score = 37.0 bits (84), Expect = 0.055
Identities = 53/220 (24%), Positives = 77/220 (35%), Gaps = 45/220 (20%)
Query: 167 QSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRG 226
QSQ A + S+ + TP PL + P+ PSLQT +P P
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPS---PSAPPSLQT---------LPSPPATP 361
Query: 227 GQQASSKLGP---QASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQG 283
QA++ LG QA+ + P + + PP L L P + PS
Sbjct: 362 PSQATTSLGSPTLQATHSFLPSP------PLSPLATPPPQAPPALALPPLQAPPSP---- 411
Query: 284 QRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPAS 343
P + L + P+P + QA +P V PAS
Sbjct: 412 --------------PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 344 RQAAAKLALRKQLEKTL----LEIPPPKPPAPEMNFLPSA 379
+ Q +L L++PP P +P M+ PSA
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS--PSA 495
Score = 33.5 bits (75), Expect = 0.61
Identities = 45/184 (24%), Positives = 65/184 (35%), Gaps = 17/184 (9%)
Query: 190 PPPLVRGTQNIPAGKP--SLQTSSARMPGSVIPPPL-VRGGQQASSKLGPQASSQVVMPP 246
P P V+ + PA P T ++ P S+ PPL V AS + P A+ PP
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503
Query: 247 LVRGAQQIHSIRQHSSTGPPPLLLAPRASVPS--VQIQGQRIIQQGLIRVANVPNTSLLV 304
+ A + + PP L P ++PS GQ A++P + L
Sbjct: 504 PL--AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS----ASLPMSPLAT 557
Query: 305 NIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIP 364
PQ P ++PT A P + + +L L L P
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL------ALAPGP 611
Query: 365 PPKP 368
PP P
Sbjct: 612 PPPP 615
Score = 30.4 bits (67), Expect = 5.2
Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 21/228 (9%)
Query: 170 IQKEATAQKPTGSVGST----VTTPPPLVRGTQNIPAGK--PSLQTSSARMPGSVIPPPL 223
I + A PT S G++ + PP RG + PA P +S R G+ P PL
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 224 VRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHS--STGPPPLLLAPRASVPSVQI 281
+ G + S++ P R A + R S + G P +A R+ ++
Sbjct: 130 GQKGLRISAEETVARGKATEAPK--RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 282 QGQRIIQQGLIRVANV-PNTSLLV----NIPQPTPASLKGTTATSAQANSTPTSVASVVT 336
R R P S+ + +P+PA+ + +A S++S T
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 337 SAESPASRQAAAKLALR------KQLEKTLLEIPPPKPPAPEMNFLPS 378
SPA +A+ R + K L + PP+ P + P+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 40.0 bits (92), Expect = 0.007
Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 48/211 (22%)
Query: 190 PPPLVRGTQNI-----PAGKPSLQ-----TSSARMPGSVIPPPLVRGGQQASSKLG---- 235
PPP +G Q++ PAG P Q TS+ + P S PP G+Q+ G
Sbjct: 485 PPP--QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
Query: 236 PQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVA 295
P A+ P R A + RQ S +GP P P+AS GQ+ +QG
Sbjct: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAP----PKAS--GAPPGGQQ--RQG----- 589
Query: 296 NVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQ 355
P P G T ++QA P + T+ + S A +
Sbjct: 590 -----------PPQKPPGPAGPTRQASQAGPVPRT--GPPTTQQPRPSGPGPAGRPKPQL 636
Query: 356 LEKTLLEIPPPK------PPAPEMNFLPSAA 380
+K ++PPP PP P++ P+ A
Sbjct: 637 AQKPSQDVPPPATAAAGGPPHPQLKASPAQA 667
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 39.3 bits (90), Expect = 0.011
Identities = 37/187 (19%), Positives = 56/187 (29%), Gaps = 2/187 (1%)
Query: 185 STVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVM 244
ST TTPPP + P T S + PPP ++ + P AS+ +
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 245 PPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLV 304
P + +T P P P S P +
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 305 NIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIP 364
+ P T S T T+ +TP+ + T+ + + T L P
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL--P 1636
Query: 365 PPKPPAP 371
P P+P
Sbjct: 1637 PTTTPSP 1643
Score = 34.3 bits (77), Expect = 0.36
Identities = 47/169 (27%), Positives = 67/169 (39%), Gaps = 34/169 (20%)
Query: 177 QKPTGSVGSTVTT--PPPLVRGTQNIPAGKPSLQTSSARMPGSVI--PPPLVRGGQQASS 232
Q PT + +T TT P P GTQ P TS+A + PPP Q + S
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQT----GPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226
Query: 233 KLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLI 292
P S ++ L + +ST PP AP + G
Sbjct: 4227 TSSPLTESTTLLSTLPPAIEM-------TSTAPPSTPTAPTTT-------------SGGH 4266
Query: 293 RVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESP 341
++ P+T+ P TP +GTT S+ A TP++V + TSA +P
Sbjct: 4267 TLSPPPSTT---TSPPGTPT--RGTTTGSSSA-PTPSTVQTTTTSAWTP 4309
Score = 32.3 bits (72), Expect = 1.4
Identities = 45/199 (22%), Positives = 68/199 (34%), Gaps = 35/199 (17%)
Query: 177 QKPTGSVGSTVTT--PPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKL 234
Q PT + +T TT P P GTQ P P T++ V P P G Q ++
Sbjct: 4056 QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTT------VTPTPTPTGTQTPTTT- 4107
Query: 235 GPQASSQVVMP-PLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIR 293
P ++ V P P G Q + ++T P P+
Sbjct: 4108 -PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-------------- 4152
Query: 294 VANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALR 353
P T+ P PTP + T T +T T + + P + + A +A
Sbjct: 4153 ---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIA-- 4207
Query: 354 KQLEKTLLEIPPPKPPAPE 372
+ PPP+ P+
Sbjct: 4208 ----ELTTSNPPPESSTPQ 4222
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 393 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 452
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 453 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 512
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 513 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 563
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 564 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 616
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 617 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 665
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 723
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 673 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 729
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 730 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 777
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 778 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 828
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 590 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 640
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 641 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 693
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 694 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 742
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 800
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 854
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 855 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 590 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 640
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 641 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 693
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 694 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 742
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 800
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 854
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 855 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 393 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 452
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 453 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 512
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 513 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 563
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 564 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 616
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 617 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 665
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 723
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 673 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 729
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 730 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 777
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 778 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 828
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 590 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 640
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 641 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 693
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 694 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 742
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 800
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 854
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 855 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 39.3 bits (90), Expect = 0.011
Identities = 78/358 (21%), Positives = 131/358 (36%), Gaps = 43/358 (12%)
Query: 30 KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATE---ATAMAMG---RGEGLVGDGPV 83
K E +S +D D A + L ++ + A+ M MG +G G V G V
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 84 DMRTSHSDM---KSERRPPSPDVIVLSDNEQPSS--PRVNGLTTVALKETSTEALMKSSP 138
T + + + + S + SD E P++ P L+ T + K P
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 139 EERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQ 198
++ + Q+K E ++ + +S + +A T P ++ Q
Sbjct: 590 QKAGPVAVQVKAEKPMDNS---------ESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 640
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG----PQASSQVVMPPLVRGAQQI 254
K + T+SA+ V P VR G QA K G P SS V R A+
Sbjct: 641 TKACPKKTNTTASAK----VAP---VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 693
Query: 255 HSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGL-IRVANVPNTSLLVNIPQPTPAS 313
S + S L +V + + + +GL ++ A+VP ++ Q T
Sbjct: 694 SSSEESDSEEEKTGL--------AVTVGQAKSVGKGLQVKAASVPVKG---SLGQGTAPV 742
Query: 314 LKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAP 371
L G T + S + ES + AA+ ++ ++KT + P AP
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 800
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 443 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI 502
T Q KA K E + +++ ++ +E ++ QAKA P AA P K I
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 503 KPRRKLAFRSGEARDWSNGAVL------QASSQLSRGSATTPRGVLHTFSPSPKLQNSAS 556
K+ + +A+ S V Q S+ L+RG A+ P A
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VGKAV 854
Query: 557 ATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQRE 615
ATA ++TG + S +S + TLA V PS H+ +A+ +E
Sbjct: 855 ATAAQAQTGPEED--------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
>gi|154426272 hypothetical protein LOC54540 [Homo sapiens]
Length = 789
Score = 39.3 bits (90), Expect = 0.011
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 13/170 (7%)
Query: 206 SLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGP 265
S+ ++ G+ P P S Q + + PL G+ Q H+++ P
Sbjct: 463 SMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAP 522
Query: 266 P-PLLLAPRASVPSVQIQGQR---IIQQGLIRVAN-VPNTSLLVNIPQPTPASLKGTTAT 320
P + P P +++G + + GL+R N VPN S ++ + P P +
Sbjct: 523 PWAEMRGPHP--PWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPS 580
Query: 321 SAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPA 370
S + S + V+S P + A + + P P+PPA
Sbjct: 581 SKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEAS------PAPRPPA 624
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 38.9 bits (89), Expect = 0.015
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 19/129 (14%)
Query: 140 ERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSV-GSTVTTPPPLVRGTQ 198
ERER ++ +E+L E+ L ++ R S A+ + P SV G + + P L +Q
Sbjct: 239 ERERQERERQEQLEREQ--LEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIR 258
PA PS Q PPPL G QAS L P PPL
Sbjct: 297 --PAETPSQQGIVLGPLAPPPPPPLPPGPAQASVAL-PPPPGPPPPPPL----------- 342
Query: 259 QHSSTGPPP 267
STGPPP
Sbjct: 343 --PSTGPPP 349
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 38.9 bits (89), Expect = 0.015
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 19/129 (14%)
Query: 140 ERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSV-GSTVTTPPPLVRGTQ 198
ERER ++ +E+L E+ L ++ R S A+ + P SV G + + P L +Q
Sbjct: 239 ERERQERERQEQLEREQ--LEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
Query: 199 NIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIR 258
PA PS Q PPPL G QAS L P PPL
Sbjct: 297 --PAETPSQQGIVLGPLAPPPPPPLPPGPAQASVAL-PPPPGPPPPPPL----------- 342
Query: 259 QHSSTGPPP 267
STGPPP
Sbjct: 343 --PSTGPPP 349
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 38.9 bits (89), Expect = 0.015
Identities = 63/306 (20%), Positives = 105/306 (34%), Gaps = 38/306 (12%)
Query: 86 RTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMI 145
+T S K +PP+ + S + +V+ + S+ + SS R I
Sbjct: 86 QTIKSTTKRSPKPPNKK----KTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 141
Query: 146 KQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSV------------GSTVTTPPPL 193
K K E L KKL+ +K T +KPT G T P
Sbjct: 142 KSSKNSAANRE----LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDT 197
Query: 194 VRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQ 253
N + P + T+ P +PP +S + S V V +
Sbjct: 198 STTQHNKVSTSPKITTAKPINPRPSLPP---------NSDTSKETSLTVNKETTVETKET 248
Query: 254 IHSIRQHSSTGPPPLLLAPRA-SVPSVQIQG----QRIIQQGLIRVANVPNTSLLVNIPQ 308
+ +Q S+ G A S+ + +++ + + L +
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 308
Query: 309 PTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIP---P 365
PTP + K +T+ + TPT++ S T+ + PA + K+ T + P
Sbjct: 309 PTPTTPKEPASTTPK-EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 366 PKPPAP 371
PK PAP
Sbjct: 368 PKEPAP 373
Score = 35.8 bits (81), Expect = 0.12
Identities = 45/236 (19%), Positives = 92/236 (38%), Gaps = 15/236 (6%)
Query: 260 HSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVN---IPQPTPASLKG 316
H+ T PP AP S S I+ + + N T ++ I + S
Sbjct: 67 HNPTSPPSSKKAPPPSGASQTIKSTT---KRSPKPPNKKKTKKVIESEEITEEHSVSENQ 123
Query: 317 TTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFL 376
+++S+ ++S+ +++ + +S S A+R+ KL ++ + + P PKPP +
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD-EAG 182
Query: 377 PSAANNEF-IYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGA 435
N +F + N + T +++ A ++ P + T K
Sbjct: 183 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 242
Query: 436 IMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPT 491
+ + TTN++ TS + ++ Q IE+ + ++ A+PT
Sbjct: 243 VETKETTTTNKQ-------TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 291
Score = 34.3 bits (77), Expect = 0.36
Identities = 51/218 (23%), Positives = 90/218 (41%), Gaps = 35/218 (16%)
Query: 13 RALERDPTEDDVESKKI----KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATEATA 68
+ALE P E V + K K E A D T+ D+R TPE T + T+ TA
Sbjct: 846 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE----TTTAAPKMTKETA 901
Query: 69 MAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSP-RVNGL--TTVAL 125
+ ++ +E + + V S Q ++P ++ L TT+A
Sbjct: 902 -------------------TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942
Query: 126 KETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGS--- 182
K T+T+ + ++ E + + K + R +K K + ++ K+ T+ K +
Sbjct: 943 KVTTTKKTI-TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1001
Query: 183 VGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIP 220
V TTP P + T +P P+ + + A + + P
Sbjct: 1002 VRKPKTTPTPR-KMTSTMPELNPTSRIAEAMLQTTTRP 1038
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 38.9 bits (89), Expect = 0.015
Identities = 63/306 (20%), Positives = 105/306 (34%), Gaps = 38/306 (12%)
Query: 86 RTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMI 145
+T S K +PP+ + S + +V+ + S+ + SS R I
Sbjct: 127 QTIKSTTKRSPKPPNKK----KTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 182
Query: 146 KQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSV------------GSTVTTPPPL 193
K K E L KKL+ +K T +KPT G T P
Sbjct: 183 KSSKNSAANRE----LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDT 238
Query: 194 VRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQ 253
N + P + T+ P +PP +S + S V V +
Sbjct: 239 STTQHNKVSTSPKITTAKPINPRPSLPP---------NSDTSKETSLTVNKETTVETKET 289
Query: 254 IHSIRQHSSTGPPPLLLAPRA-SVPSVQIQG----QRIIQQGLIRVANVPNTSLLVNIPQ 308
+ +Q S+ G A S+ + +++ + + L +
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 349
Query: 309 PTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIP---P 365
PTP + K +T+ + TPT++ S T+ + PA + K+ T + P
Sbjct: 350 PTPTTPKEPASTTPK-EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 366 PKPPAP 371
PK PAP
Sbjct: 409 PKEPAP 414
Score = 35.8 bits (81), Expect = 0.12
Identities = 45/236 (19%), Positives = 92/236 (38%), Gaps = 15/236 (6%)
Query: 260 HSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVN---IPQPTPASLKG 316
H+ T PP AP S S I+ + + N T ++ I + S
Sbjct: 108 HNPTSPPSSKKAPPPSGASQTIKSTT---KRSPKPPNKKKTKKVIESEEITEEHSVSENQ 164
Query: 317 TTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFL 376
+++S+ ++S+ +++ + +S S A+R+ KL ++ + + P PKPP +
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD-EAG 223
Query: 377 PSAANNEF-IYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGA 435
N +F + N + T +++ A ++ P + T K
Sbjct: 224 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 283
Query: 436 IMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPT 491
+ + TTN++ TS + ++ Q IE+ + ++ A+PT
Sbjct: 284 VETKETTTTNKQ-------TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 332
Score = 34.3 bits (77), Expect = 0.36
Identities = 51/218 (23%), Positives = 90/218 (41%), Gaps = 35/218 (16%)
Query: 13 RALERDPTEDDVESKKI----KMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATEATA 68
+ALE P E V + K K E A D T+ D+R TPE T + T+ TA
Sbjct: 887 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE----TTTAAPKMTKETA 942
Query: 69 MAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSP-RVNGL--TTVAL 125
+ ++ +E + + V S Q ++P ++ L TT+A
Sbjct: 943 -------------------TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983
Query: 126 KETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGS--- 182
K T+T+ + ++ E + + K + R +K K + ++ K+ T+ K +
Sbjct: 984 KVTTTKKTI-TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1042
Query: 183 VGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIP 220
V TTP P + T +P P+ + + A + + P
Sbjct: 1043 VRKPKTTPTPR-KMTSTMPELNPTSRIAEAMLQTTTRP 1079
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 38.9 bits (89), Expect = 0.015
Identities = 58/254 (22%), Positives = 90/254 (35%), Gaps = 42/254 (16%)
Query: 162 LKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPA-GKPSLQTSSARM------ 214
L L ++ +++ P+ T PPL +N+P+ P LQT+SA +
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPL----ENLPSLAPPPLQTASAPLTTPHLE 559
Query: 215 --------PGSVIPPPLVRGGQQASSKLG---PQASSQVVMPPLVR-GAQQIHSIRQHSS 262
P P PL + S + PQA + PPL + + +
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 263 TGPPPLLLAPRASVPSVQI------------QGQRIIQQGLIRVANVPNTSLLVNIPQPT 310
PP L L P + PS Q + L++ P S V P
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
Query: 311 PASLKGTTATSAQANSTPTSVASVVT-----SAESPASRQAAAKLALRKQLEKTLLEIPP 365
PAS + + + + + P+ A + A P S A L L++PP
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
Query: 366 PKPPAPEMNFLPSA 379
P +P M+ PSA
Sbjct: 740 SPPASPPMS--PSA 751
Score = 38.5 bits (88), Expect = 0.019
Identities = 53/197 (26%), Positives = 71/197 (36%), Gaps = 26/197 (13%)
Query: 190 PPPLVRGTQNIPAGKP--SLQTSSARMPGSVIPPPL-VRGGQQASSKLG------PQASS 240
P P V+ + PA P T ++ P S+ PPL V AS + PQA
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 241 QVVMPPL-VRGAQQIHSIRQHSSTGP---PPLLLAPRASVPSVQIQGQRIIQQGLIRVAN 296
+ PPL V + S+T P PPLL AP VP A+
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP-------------PAS 775
Query: 297 VPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQL 356
+P + L PQ PA ++ A SA P S A L
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 357 EKTLLEIPPPKPPAPEM 373
LL++PP P +P +
Sbjct: 836 AAPLLQVPPSPPASPTL 852
Score = 38.1 bits (87), Expect = 0.025
Identities = 58/220 (26%), Positives = 84/220 (38%), Gaps = 40/220 (18%)
Query: 187 VTTPPPLVRGTQNIPAGKPSLQT--SSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVM 244
+ TP PL + P+ PSLQT S P S PP + QA L +
Sbjct: 337 LATPLPLAPPS---PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ-------TI 386
Query: 245 PPLVRGAQQIHSIRQHSSTGPP-PLLLAPRASV-----PSVQI------QGQRIIQQGLI 292
PP+ Q HS+ S PP PL L+ + P++Q R Q L
Sbjct: 387 PPI----QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442
Query: 293 ---RVANVPNTSLLVNIPQPTPAS--LKGTTATSAQANSTPTSVASVVT-------SAES 340
R A+ P S + P PAS L+ + + + S+P ++ + S ++
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 341 PASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAA 380
P S L + L L+ PP P + LPS A
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Score = 34.7 bits (78), Expect = 0.27
Identities = 65/293 (22%), Positives = 108/293 (36%), Gaps = 45/293 (15%)
Query: 121 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 180
T V L + A + E + + E E + + +Q+ A+ +
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS--RSL 242
Query: 181 GSVGSTVTTPP---PLVRGTQNIPA--GKPSLQTSSARMPGSVIPPPLVRGGQQASSKLG 235
S + +++P P RGT PA +P + A P V PP + A+ LG
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-----KDAAPALG 297
Query: 236 PQASSQVV-----------MPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQ 284
P +SS + +PP A + + S PL LAP + PS Q
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQ 355
Query: 285 RIIQQGLIRVANVPNTSLLVNIPQPTPASLK---------GTTATSAQANSTPTSVASV- 334
+ + P + + P P SL+ T+ S QA +P +++S+
Sbjct: 356 TLPSPPATPPSQAPPS--MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
Query: 335 -VTSAESPASRQAAAKLALR-KQLEKTL------LEIPPPKPPAPEMNFLPSA 379
TS SP + + L + +Q + +L PP PP LP++
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
Score = 30.4 bits (67), Expect = 5.2
Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 21/228 (9%)
Query: 170 IQKEATAQKPTGSVGST----VTTPPPLVRGTQNIPAGK--PSLQTSSARMPGSVIPPPL 223
I + A PT S G++ + PP RG + PA P +S R G+ P PL
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 224 VRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHS--STGPPPLLLAPRASVPSVQI 281
+ G + S++ P R A + R S + G P +A R+ ++
Sbjct: 130 GQKGLRISAEETVARGKATEAPK--RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 282 QGQRIIQQGLIRVANV-PNTSLLV----NIPQPTPASLKGTTATSAQANSTPTSVASVVT 336
R R P S+ + +P+PA+ + +A S++S T
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 337 SAESPASRQAAAKLALR------KQLEKTLLEIPPPKPPAPEMNFLPS 378
SPA +A+ R + K L + PP+ P + P+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,113,826
Number of Sequences: 37866
Number of extensions: 1404493
Number of successful extensions: 9068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 426
Number of HSP's that attempted gapping in prelim test: 7884
Number of HSP's gapped (non-prelim): 1542
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.