Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157785649
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157785649 leucine-rich repeats and IQ motif containing 3
[Homo sapiens]
(624 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157785649 leucine-rich repeats and IQ motif containing 3 [Hom... 1262 0.0
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 55 2e-07
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 53 7e-07
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 52 2e-06
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 51 4e-06
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 48 2e-05
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 47 5e-05
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 47 5e-05
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 46 9e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 3e-04
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 44 4e-04
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 44 4e-04
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 44 4e-04
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 43 0.001
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 43 0.001
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 43 0.001
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 43 0.001
gi|4826651 hypothetical protein LOC755 [Homo sapiens] 42 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 0.002
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 42 0.002
gi|148746195 trichohyalin [Homo sapiens] 41 0.003
gi|148746218 TAO kinase 3 [Homo sapiens] 41 0.003
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens] 41 0.003
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 41 0.003
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 40 0.005
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 40 0.005
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 40 0.005
gi|7706093 toll-like receptor 7 [Homo sapiens] 40 0.006
gi|21687175 leucine rich transmembrane and 0-methyltransferase d... 40 0.006
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 40 0.006
>gi|157785649 leucine-rich repeats and IQ motif containing 3 [Homo
sapiens]
Length = 624
Score = 1262 bits (3265), Expect = 0.0
Identities = 624/624 (100%), Positives = 624/624 (100%)
Query: 1 MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNN 60
MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNN
Sbjct: 1 MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNN 60
Query: 61 FITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSA 120
FITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSA
Sbjct: 61 FITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSA 120
Query: 121 CPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHR 180
CPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHR
Sbjct: 121 CPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHR 180
Query: 181 LFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFF 240
LFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFF
Sbjct: 181 LFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFF 240
Query: 241 HKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNS 300
HKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNS
Sbjct: 241 HKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNS 300
Query: 301 SEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYT 360
SEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYT
Sbjct: 301 SEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYT 360
Query: 361 SGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTF 420
SGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTF
Sbjct: 361 SGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTF 420
Query: 421 SDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQ 480
SDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQ
Sbjct: 421 SDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQ 480
Query: 481 NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEK 540
NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEK
Sbjct: 481 NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEK 540
Query: 541 NEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERL 600
NEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERL
Sbjct: 541 NEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERL 600
Query: 601 QDAKTKVAIVKTNLDFKVPNGLIK 624
QDAKTKVAIVKTNLDFKVPNGLIK
Sbjct: 601 QDAKTKVAIVKTNLDFKVPNGLIK 624
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 55.1 bits (131), Expect = 2e-07
Identities = 46/151 (30%), Positives = 76/151 (50%), Gaps = 10/151 (6%)
Query: 25 EGQKDFVFVKFNGL---HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHG 81
EG K+ V +++ L +LK+ME + SC +L+ S+N I+ I L + L L LHG
Sbjct: 96 EGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQIGDLSKLVSLKTLLLHG 155
Query: 82 NQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKK--- 138
N I SL + ++L +L L +N L I L++ L L++ + P +
Sbjct: 156 NIITSLRMAPAYLP-RSLAILSLAENEIRDLNEISFLASLTELEQLSIMNNPCVMATPSI 214
Query: 139 ---GYRHVLVNSIWPLKALDHHVISDEEIIQ 166
YR +V+ L+ LD +VIS +E ++
Sbjct: 215 PGFDYRPYIVSWCLNLRVLDGYVISQKESLK 245
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 53.1 bits (126), Expect = 7e-07
Identities = 34/139 (24%), Positives = 67/139 (48%), Gaps = 3/139 (2%)
Query: 25 EGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQI 84
E K + +G + +EN+ LRV + NF++ + L L +L+L NQI
Sbjct: 175 ENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQI 234
Query: 85 KSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVL 144
+ + + L L+ L+L N + ++ L+ +L +T P++ + Y+H +
Sbjct: 235 TFVRDV---DNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTV 291
Query: 145 VNSIWPLKALDHHVISDEE 163
+ ++ L+ LD I++EE
Sbjct: 292 LQNMMQLRQLDMKRITEEE 310
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 52 LRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAK 111
LR+ F +NFIT I + + KLI LDL+ NQI+ + + L+ L++L L N K
Sbjct: 114 LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGL---STLRCLRVLLLGKNRIKK 170
Query: 112 LKNI 115
+ N+
Sbjct: 171 ISNL 174
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 36 NGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNG 95
+G + +EN+ LRV + NF++ + L L +L+L NQI + + +
Sbjct: 11 HGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV---DN 67
Query: 96 LKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALD 155
L L+ L+L N + ++ L+ +L +T P++ + Y+H ++ ++ L+ LD
Sbjct: 68 LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLD 127
Query: 156 HHVISDEE 163
I++EE
Sbjct: 128 MKRITEEE 135
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 50.8 bits (120), Expect = 4e-06
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 27/154 (17%)
Query: 34 KFNGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIK-------------------- 73
K G K +ENL+ C+ L V S N I I L +K
Sbjct: 109 KDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENM 168
Query: 74 --LIKLDLHGNQIKSLPNTKFWNG--LKNLKLLYLHDNGFAKLKNICVLSACPTLIALTM 129
L KL+L GN+I+ +P W G LK+L++L L N + L++I L LI+L +
Sbjct: 169 CNLQKLNLAGNEIEHIP---VWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLIL 225
Query: 130 FDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEE 163
+ PV Y + + L++L+ ++ ++
Sbjct: 226 VENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQD 259
Score = 32.7 bits (73), Expect = 1.0
Identities = 38/150 (25%), Positives = 64/150 (42%), Gaps = 33/150 (22%)
Query: 431 KKQEYHKEKV---------RVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQN 481
K+Q++ EK +V++ A ERVR E ++ E ++T+
Sbjct: 1972 KEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEE---------ERWCESLEKTLSQ 2022
Query: 482 SLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKN 541
+ RQ+ + +EK+ E AL + S +A LL ER + EK
Sbjct: 2023 TKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTER----------KKAEKQ 2072
Query: 542 EAVLKEKSLIVKQKLKAEKYRKNLLKEMKK 571
A LKE I + +L+ KNLL++ ++
Sbjct: 2073 VASLKEALKIQRSQLE-----KNLLEQKQE 2097
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/137 (30%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 36 NGLHLKSMENLQSCIS------LRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPN 89
N +HL N + I+ +++ SNN I I L+ L LDL NQI SL
Sbjct: 238 NLIHLSLANNKITTINGLNKLPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSL-- 295
Query: 90 TKFWNGLKN---LKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVN 146
GL+N L+++ L DN A+L+ I + P L L + + P+ K Y ++
Sbjct: 296 ----QGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIF 351
Query: 147 SIWPLKALDHHVISDEE 163
+ L LD I EE
Sbjct: 352 MLLRLTELDQKKIKVEE 368
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/63 (31%), Positives = 34/63 (53%)
Query: 39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKN 98
+L + N + +L+ FS+N I++I L + L KL L GN+I+ + + N L +
Sbjct: 182 NLTTFFNFKPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIH 241
Query: 99 LKL 101
L L
Sbjct: 242 LSL 244
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 47.0 bits (110), Expect = 5e-05
Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
Query: 471 LIEENKETIQ-NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLT 529
+I EN++T + NS+ + + YL+ + K+ + SE L +++ T
Sbjct: 370 IISENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTT 429
Query: 530 RGLL-KIDRLEKN-EAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQ----EIYKRHCE 583
+ L+ K++ EK + +++EKS I + K E+Y K LKE KK+ S+ + + E
Sbjct: 430 QSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTLE 489
Query: 584 EKFVMDMIAFEKACERLQDAKTKVAIVKTNLDFKVPN 620
EK + + ++ E L K+K KT D + N
Sbjct: 490 EKNIQLSLEKQQMMEALDQLKSKEH--KTQSDMAIVN 524
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 47.0 bits (110), Expect = 5e-05
Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
Query: 471 LIEENKETIQ-NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLT 529
+I EN++T + NS+ + + YL+ + K+ + SE L +++ T
Sbjct: 407 IISENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTT 466
Query: 530 RGLL-KIDRLEKN-EAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQ----EIYKRHCE 583
+ L+ K++ EK + +++EKS I + K E+Y K LKE KK+ S+ + + E
Sbjct: 467 QSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTLE 526
Query: 584 EKFVMDMIAFEKACERLQDAKTKVAIVKTNLDFKVPN 620
EK + + ++ E L K+K KT D + N
Sbjct: 527 EKNIQLSLEKQQMMEALDQLKSKEH--KTQSDMAIVN 561
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 46.2 bits (108), Expect = 9e-05
Identities = 78/360 (21%), Positives = 152/360 (42%), Gaps = 62/360 (17%)
Query: 260 ITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNSSEHRKHVSSILCELKPKDL 319
I K E+K LK+L K E + +LA KH KD
Sbjct: 73 IQKAEENKRLKELQLKQEEKLAMELAKLKHE------------------------SLKDE 108
Query: 320 GMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYTSGSLKNNAVLREKKQHFFP 379
M+ + + I+ + +++KL ++ I ++K + R+ +
Sbjct: 109 KMRQQVRENSIELRE------LEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAE----- 157
Query: 380 AYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQ--KKQEYH- 436
+ + H K IIK++ E +R K + + D++K EQ KKQE +
Sbjct: 158 -IAKTMMEEH-KRIIKEENAAE--------DKRNKAKAQYYLDLEKQLEEQEKKKQEAYE 207
Query: 437 ---KEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNY 493
KEK+ + + + E ++ + L +K A ++ IEE ++ + +W+ +
Sbjct: 208 QLLKEKLMIDEIVRKIYEEDQLEKQQKL-EKMNAMRRYIEEFQKE-----QALWRKKKRE 261
Query: 494 LEKARERKAL-FLKEKSQKASERLLVQNLNNERTLLTRGLL--KIDRLEKNEAVLKEKSL 550
+ RK + F + Q+ +R+ N E+ L + L K++ + + L++
Sbjct: 262 EMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQ 321
Query: 551 IVKQKLKAEKYRKNLLKEM-KKVRSQEIYKRHCEEKFVMDMIAFEKACERLQD-AKTKVA 608
+ Q+ +AE Y+ L +E KK+R Q+ K+ EE+ + + + A E ++ KT +A
Sbjct: 322 ELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLA 381
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/219 (20%), Positives = 100/219 (45%), Gaps = 13/219 (5%)
Query: 393 IIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARER 452
I +++ R E+ K + ++ + + +K Q+++ + +EK+R Q E
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Query: 453 VRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKA 512
R H ++ + ++ + E +E I+ +VW+ EK RE++ EK ++
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE----EKIREQE-----EKIREQ 529
Query: 513 SERLLVQNLN-NERTLLTRGLLKIDRLEK---NEAVLKEKSLIVKQKLKAEKYRKNLLKE 568
E++ Q E+ + R K+ EK E +++ + +Q+ K + + + ++
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 569 MKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQDAKTKV 607
+K+R QE ++ EEK + E++Q+ + K+
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/199 (20%), Positives = 93/199 (46%), Gaps = 26/199 (13%)
Query: 424 DKYYTEQKKQEYH---KEKVRVVAMAQVARERVRVAVNEHL----NQKKYATQKLIEENK 476
+K E+K+QE +++ ++ ++ R++ ++ E +K + ++ I E +
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 477 ETIQNSLRQVWQNR---------FNYLEKARERKALFLKEKSQKASERLLVQN--LNNER 525
E I+ ++W+ + EK E++ ++ +EK Q+ +++ Q + +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 526 TLLTRGLLKI-----DRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKR 580
+ R KI R E+ E + K++ I +Q+ K ++ + + ++ +K+R QE +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 581 HCEEKFVMDMIAFEKACER 599
EEK EK CE+
Sbjct: 644 EQEEKMGEQE---EKMCEQ 659
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/158 (20%), Positives = 73/158 (46%), Gaps = 21/158 (13%)
Query: 429 EQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKK-YATQKLIEENKETIQNSLRQVW 487
E +++ + +EK+R + E++R + K + ++ I E +E I+ +++W
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 488 QNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKE 547
+ EK E++ + +EK Q+ E + +++ + E + ++
Sbjct: 455 RQE----EKIHEQEKIREEEKRQEQEEMWRQE----------------EKIHEQEEIWRQ 494
Query: 548 KSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
K + +Q+ K K + + ++ +K+R QE R EEK
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 20/187 (10%)
Query: 424 DKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL 483
+K + E+K+QE + R E++R +K + ++ I E +E Q
Sbjct: 557 EKIWEEEKRQEQEDKMWR-------QEEKIR-----EQEEKVWRQEEKIREQEEKRQEQE 604
Query: 484 RQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEA 543
++W+ E+ E K +EK ++ E++ Q + G + E+ E
Sbjct: 605 EKMWKQEEKIREQ--EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 544 VLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKAC---ERL 600
+ +++ + +Q+ K + K + ++ +K+R QE + EEK EK C E++
Sbjct: 663 MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE---EKMCEQEEKM 719
Query: 601 QDAKTKV 607
Q+ + K+
Sbjct: 720 QEQEEKM 726
Score = 35.0 bits (79), Expect = 0.21
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 11/147 (7%)
Query: 429 EQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQ 488
EQK H+E +R AQV R+ L Y +Q +++ ++ R +
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQ----LEGEARDLIS 165
Query: 489 NRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEK 548
+ + A E + +QK ++ L ER L+ L++ R + LKEK
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS---LELYRNTITDEELKEK 222
Query: 549 SLIVKQKLKAEKYRKNLL----KEMKK 571
+ +++KL+ + K+ + KE+K+
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKR 249
Score = 32.7 bits (73), Expect = 1.0
Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 13/161 (8%)
Query: 428 TEQKKQEYHKE---KVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLR 484
T++KK + + E K R ++ R + + N K +L+E K IQ +++
Sbjct: 186 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 485 QVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAV 544
+ L++ ER L L ++ +A L + L + L + + + +
Sbjct: 246 E--------LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297
Query: 545 LKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
+EK + +Q+ K +++ + + ++ +K+R QE R EEK
Sbjct: 298 QEEK--MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Score = 32.7 bits (73), Expect = 1.0
Identities = 28/162 (17%), Positives = 73/162 (45%), Gaps = 27/162 (16%)
Query: 424 DKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL 483
+K +++K + +EK+R Q + R + + + +K ++ + E +E +Q
Sbjct: 612 EKIREQEEKIQEQEEKIR----EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 484 RQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEA 543
+W+ EK RE++ +++ + + ++Q E+ E
Sbjct: 668 ETMWRQE----EKIREQEKKIREQEEKIREQEEMMQ-------------------EQEEK 704
Query: 544 VLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
+ +++ + +Q+ K ++ + + ++ +K+ QE+ R EEK
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/196 (23%), Positives = 85/196 (43%), Gaps = 21/196 (10%)
Query: 408 FAPQRAGMKLRTFSDIDKYYTEQKKQEYHK-------EKVRVVAMAQVARERVRVAVNEH 460
FAP + K +T K T EY K + ++ + + E + A N
Sbjct: 133 FAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIE-AKNRE 191
Query: 461 LNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQN 520
L KK +NK+ ++ R+ + R +E+ R+R+ K K ++ +R ++
Sbjct: 192 LIAKKTTPLLSFLKNKQRMREEKRE--ERRRREIERKRQREEERRKWKEEEKRKRKDIEK 249
Query: 521 LNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKR 580
L KIDR+ + + + E + V + L +KNLLK+ +K +E+ KR
Sbjct: 250 LK-----------KIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKR 298
Query: 581 HCEEKFVMDMIAFEKA 596
+K + ++ E+A
Sbjct: 299 EKAKKLDKENLSDERA 314
>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
Query: 37 GLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGL 96
G++L ++NL + N + + L+ L L L NQI +L F +
Sbjct: 196 GINLPKLKNLY---------LAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG--FSREM 244
Query: 97 KNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDH 156
K+L+ L L N A L + L P L AL + D P + + YR + + L+ LD
Sbjct: 245 KSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDK 304
Query: 157 HVISDEEIIQNWHLPERFK 175
+EE + + +R K
Sbjct: 305 EFYEEEERAEADVIRQRLK 323
Score = 30.8 bits (68), Expect = 3.9
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 46 LQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKS 86
L+S I LR S N +TD+ PL L+ L GN+++S
Sbjct: 87 LRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRS 127
>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
Query: 37 GLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGL 96
G++L ++NL + N + + L+ L L L NQI +L F +
Sbjct: 196 GINLPKLKNLY---------LAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG--FSREM 244
Query: 97 KNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDH 156
K+L+ L L N A L + L P L AL + D P + + YR + + L+ LD
Sbjct: 245 KSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDK 304
Query: 157 HVISDEEIIQNWHLPERFK 175
+EE + + +R K
Sbjct: 305 EFYEEEERAEADVIRQRLK 323
Score = 30.8 bits (68), Expect = 3.9
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 46 LQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKS 86
L+S I LR S N +TD+ PL L+ L GN+++S
Sbjct: 87 LRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRS 127
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/145 (23%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Query: 443 VAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL----RQVWQNRFNYLEKAR 498
+A+ + + +++ + E Q+K + L+E+ E ++ + +++ N NY
Sbjct: 1064 LALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123
Query: 499 ERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKN----EAVLKEKSLIVKQ 554
E + L EK Q SE L+ E +L L K+ L E LKE+ + ++
Sbjct: 1124 ELRTLMTIEKDQCISE--LISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQS 1181
Query: 555 KLKAEKYRKNLLKEMKKVRSQEIYK 579
KL +E K+ K + +E Y+
Sbjct: 1182 KLDSELSALERQKDEKITQQEEKYE 1206
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/145 (23%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Query: 443 VAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL----RQVWQNRFNYLEKAR 498
+A+ + + +++ + E Q+K + L+E+ E ++ + +++ N NY
Sbjct: 1064 LALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123
Query: 499 ERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKN----EAVLKEKSLIVKQ 554
E + L EK Q SE L+ E +L L K+ L E LKE+ + ++
Sbjct: 1124 ELRTLMTIEKDQCISE--LISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQS 1181
Query: 555 KLKAEKYRKNLLKEMKKVRSQEIYK 579
KL +E K+ K + +E Y+
Sbjct: 1182 KLDSELSALERQKDEKITQQEEKYE 1206
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/197 (18%), Positives = 88/197 (44%), Gaps = 8/197 (4%)
Query: 424 DKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL 483
+K + +++K EK++ +E E +K + +K + E E I+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 484 RQVW--QNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLE-- 539
++W + + LE+ + + L+E +K E + + + + R KI E
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE--EEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 540 --KNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKAC 597
+ E +LK++ I +Q+ K + + + ++ +K++ QE + EEK + +
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 598 ERLQDAKTKVAIVKTNL 614
E++Q+ + ++ ++ L
Sbjct: 545 EKMQEQEVRLQELEERL 561
Score = 32.7 bits (73), Expect = 1.0
Identities = 36/194 (18%), Positives = 86/194 (44%), Gaps = 29/194 (14%)
Query: 428 TEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENK----------- 476
T+++ +E + E + + + + +++ V + L +K Q L+ + +
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKD-LKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 477 -ETIQNSLR-QVWQNR-FNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLL 533
+++ L+ QV +N +N L + +E K +EK Q+ E++ Q L
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR--------- 321
Query: 534 KIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAF 593
E+ E + +++ + +Q+ K + + ++ +K+R QE R EEK
Sbjct: 322 -----EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 594 EKACERLQDAKTKV 607
+ E++Q+ + ++
Sbjct: 377 REQDEKIQEQEEEM 390
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/197 (18%), Positives = 88/197 (44%), Gaps = 8/197 (4%)
Query: 424 DKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSL 483
+K + +++K EK++ +E E +K + +K + E E I+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 484 RQVW--QNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLE-- 539
++W + + LE+ + + L+E +K E + + + + R KI E
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE--EEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 540 --KNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKAC 597
+ E +LK++ I +Q+ K + + + ++ +K++ QE + EEK + +
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 598 ERLQDAKTKVAIVKTNL 614
E++Q+ + ++ ++ L
Sbjct: 545 EKMQEQEVRLQELEERL 561
Score = 32.7 bits (73), Expect = 1.0
Identities = 36/194 (18%), Positives = 86/194 (44%), Gaps = 29/194 (14%)
Query: 428 TEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENK----------- 476
T+++ +E + E + + + + +++ V + L +K Q L+ + +
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKD-LKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 477 -ETIQNSLR-QVWQNR-FNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLL 533
+++ L+ QV +N +N L + +E K +EK Q+ E++ Q L
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR--------- 321
Query: 534 KIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAF 593
E+ E + +++ + +Q+ K + + ++ +K+R QE R EEK
Sbjct: 322 -----EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 594 EKACERLQDAKTKV 607
+ E++Q+ + ++
Sbjct: 377 REQDEKIQEQEEEM 390
>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
Length = 256
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 23/128 (17%)
Query: 37 GLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGL 96
G L + Q SL V S N I+ + P+ C +L +L L N+I SL + GL
Sbjct: 27 GSRLTDISICQEMPSLEVITLSVNSISTLEPVSRCQRLSELYLRRNRIPSLAELFYLKGL 86
Query: 97 KNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDH 156
L++L+L +N C + YR ++ ++ L+ LD+
Sbjct: 87 PRLRVLWLAEN-----------------------PCCGTSPHRYRMTVLRTLPRLQKLDN 123
Query: 157 HVISDEEI 164
+++EE+
Sbjct: 124 QAVTEEEL 131
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/194 (18%), Positives = 94/194 (48%), Gaps = 17/194 (8%)
Query: 424 DKYYTEQKKQEYH---KEKVRVVAMAQVARERVRVAVNEHLN---QKKYATQKLIEENKE 477
+K E+K+QE +++ ++ ++ R++ ++ E + +K + ++ + + +E
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
Query: 478 TIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDR 537
I+ ++W+ EK RE++ +++ + + ++Q + + + ++
Sbjct: 510 KIREQEEKMWRQE----EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 538 LEKNEAVLKEKS-LIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKA 596
+ + E ++E+ I +QK K + + + ++ +K+R QE + EEK EK
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE---EKM 622
Query: 597 C---ERLQDAKTKV 607
C E++Q+ + K+
Sbjct: 623 CEQEEKMQEQEEKM 636
Score = 35.0 bits (79), Expect = 0.21
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 11/147 (7%)
Query: 429 EQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQ 488
EQK H+E +R AQV R+ L Y +Q +++ ++ R +
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQ----LEGEARDLIS 165
Query: 489 NRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEK 548
+ + A E + +QK ++ L ER L+ L++ R + LKEK
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS---LELYRNTITDEELKEK 222
Query: 549 SLIVKQKLKAEKYRKNLL----KEMKK 571
+ +++KL+ + K+ + KE+K+
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKR 249
Score = 32.7 bits (73), Expect = 1.0
Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 13/161 (8%)
Query: 428 TEQKKQEYHKE---KVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLR 484
T++KK + + E K R ++ R + + N K +L+E K IQ +++
Sbjct: 186 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 485 QVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAV 544
+ L++ ER L L ++ +A L + L + L + + + +
Sbjct: 246 E--------LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297
Query: 545 LKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
+EK + +Q+ K +++ + + ++ +K+R QE R EEK
Sbjct: 298 QEEK--MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Score = 31.6 bits (70), Expect = 2.3
Identities = 32/171 (18%), Positives = 70/171 (40%), Gaps = 23/171 (13%)
Query: 438 EKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKA 497
+ V AQV + +N+ +K + ++ I+E +E IQ ++ + E+
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 498 ----RERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVK 553
R+ + ++ KE+ + E ++ + R L K +++ + E + E+ I +
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
Query: 554 QKLKAEKYRK-------------------NLLKEMKKVRSQEIYKRHCEEK 585
Q+ K ++ K + ++ +K+R QE EEK
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Score = 31.6 bits (70), Expect = 2.3
Identities = 32/163 (19%), Positives = 78/163 (47%), Gaps = 23/163 (14%)
Query: 424 DKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIE-ENKETIQNS 482
+K + +++K +EK+R + ++ E + Q++ +K+ E E K Q
Sbjct: 516 EKMWRQEEKIREQEEKIR--------EQEEKIREQEEMMQEQ--EEKMGEQEEKMQEQEK 565
Query: 483 LRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNE 542
+R+ + EK RE+K ++E+ +K E+ + + + ++ E+ E
Sbjct: 566 MRRQEEKIREQEEKIREQKEK-IREQEEKIWEQ--EEKIREQEEMMQ---------EQEE 613
Query: 543 AVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
+ +++ + +Q+ K ++ + + ++ +K+ QE+ R EEK
Sbjct: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/302 (18%), Positives = 132/302 (43%), Gaps = 26/302 (8%)
Query: 333 GQESEDEIVDEKLDTS-FRISVFKLPIY-TSGSLKNNAVLREKKQHFFPAYPQPIYTTHP 390
G ++++EI+ EKL + +I+ ++ ++ T +L +++ E+ Q T
Sbjct: 960 GLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQ------TQCQ 1013
Query: 391 KPIIKKDIRLERS-MKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVA 449
K ++ ++E+S +K++ A Q + + + + Q+ + HK+ +
Sbjct: 1014 KKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTI 1073
Query: 450 RERVRVAVNEHLNQKKYATQKLIEENKETIQ--NSLRQVWQNRFNYLEKARERKALFLKE 507
+++ A + + L E+NKE + N L++ R + EK + + + L E
Sbjct: 1074 QDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKE----RMDQCEKEKAGRKIDLTE 1129
Query: 508 KSQKASERLLVQNLNNERTLLTRGLLKIDRLEKN-EAVLKEKSLIVKQKLKAEKY-RKNL 565
+ R L + NE L + L + ++K E + K K + ++ + + Y +N+
Sbjct: 1130 AQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNM 1189
Query: 566 LK----EMKKVRSQEIYKRHCEEKFVMDMIAFEKAC-----ERLQDAKTKVAIVKTNLDF 616
L+ E K+ +E ++ EEK ++ +K + +Q + +KT ++
Sbjct: 1190 LERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMEL 1249
Query: 617 KV 618
+
Sbjct: 1250 TI 1251
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 428 TEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLI-------------EE 474
TE+ +QE K++++ + +++ E Q++ Q+L +E
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 475 NKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLK 534
+E +Q LR Q R E+ R+ L +E+ ++ + Q L E+ LLK
Sbjct: 524 EEERLQQRLRSEQQLR---REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 535 IDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFE 594
+ + + + +E+ ++Q+LK E+ + E ++ R Q + + EE+ ++ E
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVER---LEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 595 KACERLQ 601
+ ER Q
Sbjct: 638 EQEERRQ 644
Score = 36.6 bits (83), Expect = 0.071
Identities = 35/175 (20%), Positives = 80/175 (45%), Gaps = 18/175 (10%)
Query: 429 EQKKQEYHKEKVRVVAMAQVARERVRVA---VNEHLNQKKYATQKLIEENKETIQNSLRQ 485
E++++E + + + + Q R R+ E L Q+ + Q+L E +E + L++
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 486 VWQNRFNYLEKAR-------ERKALFLKEKSQKASERLL-VQNLNNERTLLTRGLLKIDR 537
+ R + + ER+ LK + ++ +RL Q E+ L + ++++
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 538 LEKNEAVLK-------EKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
E+ E LK + ++K + + E+ ++ L +E ++ R Q + + EE+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Score = 35.8 bits (81), Expect = 0.12
Identities = 40/231 (17%), Positives = 101/231 (43%), Gaps = 35/231 (15%)
Query: 386 YTTHPKPIIKKDIRLERSM--KEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKV--- 440
+T + KP +++ +R E+ + +E QR + R + ++ Y E+++ + +E++
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 441 ------RVVAMAQVARERVRVAVNEHL------------NQKKYATQKLIEENKETI--- 479
R Q +++ E L +KKY ++ +++ +E +
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 480 --QNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDR 537
+ RQ W+ ++ ++ ++ + L+E+ +K + + E L + ++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ----EEEQ 1062
Query: 538 LEKNEAVLKEKSLIVKQKLKAEKYR---KNLLKEMKKVRSQEIYKRHCEEK 585
L E + + + +Q K E+ + + LL+E + R ++ +R C E+
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Score = 35.4 bits (80), Expect = 0.16
Identities = 36/186 (19%), Positives = 83/186 (44%), Gaps = 15/186 (8%)
Query: 411 QRAGMKLRTFSDIDKYYTEQKKQEYHKE----KVRVVAMAQVARERVRVAVNEHLNQKKY 466
QR + R F + ++ E+++Q+ ++ K R+ +E+ R + + ++
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 467 ATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQ------- 519
Q+ + + ++ Q+ Q R +ER FL+E+ Q + Q
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 520 NLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYK 579
E LL G + R ++ + +E+ +Q+L+ ++ + L+E +++R QE+ +
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREE----EQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 580 RHCEEK 585
+ EE+
Sbjct: 1724 KFREEE 1729
Score = 32.3 bits (72), Expect = 1.3
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 38/211 (18%)
Query: 401 ERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQV-----ARERVRV 455
ER +E QR K R + D D+ K ++ EK V +V E+ R
Sbjct: 1196 ERQYREEEELQRQKRKQR-YRDEDQ--RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 456 AVNEHLN--QKKYATQKLIEENKETIQNSLRQVWQNRFNYL------------------E 495
+ L Q + Q L+ E +E + R+ WQ R +
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 496 KARERKALFLKEKSQKASERLLVQNLNNERTLLT-RGLLKIDRLEKNEAVLKE------- 547
K++E K L +E+ +K + + E LL R + R E++ +E
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 548 --KSLIVKQKLKAEKYRKNLLKEMKKVRSQE 576
K L +Q+L+ ++ + LKE +++R QE
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
Score = 30.4 bits (67), Expect = 5.1
Identities = 34/197 (17%), Positives = 88/197 (44%), Gaps = 6/197 (3%)
Query: 393 IIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARER 452
++K + + ER ++ Q+ + R + ++ EQ+ + H+E+ R +A+ +E+
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 453 VRVAVNEHLNQKKYATQKLIEENKETIQNSLR-QVWQNRFNYLEKARERKALFLKEKSQK 511
R + + + ++ + + + + + R Q Q R E+ R R+ L+ + ++
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Query: 512 ASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQK---LKAEKYRKNLLKE 568
+ R Q +R T ++ E+ L + + +Q+ L+AE+ ++ +
Sbjct: 753 RAHR--QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF 810
Query: 569 MKKVRSQEIYKRHCEEK 585
+ + +E +R E+
Sbjct: 811 LPEEEEKEQRRRQRRER 827
Score = 29.6 bits (65), Expect = 8.7
Identities = 36/174 (20%), Positives = 71/174 (40%), Gaps = 26/174 (14%)
Query: 429 EQKKQEYHKEKVR-------VVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQ- 480
EQ +QE +E++R ++ Q+ ER + +K+ ++ + + +E Q
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 481 ---------NSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRG 531
Q+ Q R + ++R + E+ Q E Q L ER R
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ-EQRLRQERDRQYRA 1847
Query: 532 LLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEK 585
+ + +EKS +Q+L E+ +K + +K+R + I ++ EE+
Sbjct: 1848 --------EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
>gi|148746218 TAO kinase 3 [Homo sapiens]
Length = 898
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/206 (21%), Positives = 95/206 (46%), Gaps = 33/206 (16%)
Query: 393 IIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARER 452
II+K+ ++ + ++ F Q + + D+ + QKKQ ++ +E+
Sbjct: 518 IIEKEAKVAAADEKKFQQQILAQQKK---DLTTFLESQKKQY------------KICKEK 562
Query: 453 VRVAVNEHLNQKKYATQKLIEENKETIQNSLRQ-----VWQNRFNYLEKAR--ERKALFL 505
++ +NE + K Q+ I ++KE +Q++ + + Q R Y + R +RK +
Sbjct: 563 IKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMI- 621
Query: 506 KEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYR--- 562
K + ++ + + LN +RT + R +++ L+ + L QKL+ + R
Sbjct: 622 --KRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQH 679
Query: 563 ----KNLLKEMKKVRSQEIYKRHCEE 584
+N L E K R +E++++H E
Sbjct: 680 QTELENQL-EYNKRRERELHRKHVME 704
>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
Length = 582
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 41 KSMENLQSCISLRVCIFSNNFITDI-HPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNL 99
K E++ +SL V I SNN + + H L + KL +LDL N+++SLPN + LK+L
Sbjct: 416 KIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAY--LKDL 473
Query: 100 KLLYLHDNGFAKL 112
+ L L +N L
Sbjct: 474 QKLVLTNNQLTTL 486
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
Query: 8 EELTSHEEWSHYNENIREGQK-------DFVFVKFNGLHLKSMENLQSCISLRVCIFSNN 60
EEL S E Y+ I++ + + + + FN L+++E + L+ NN
Sbjct: 117 EELQSLRELDLYDNQIKKIENLEALTELEILDISFN--LLRNIEGVDKLTRLKKLFLVNN 174
Query: 61 FITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSA 120
I+ I L + +L L+L N+I+++ N + L NL+ L+L N KL+N L A
Sbjct: 175 KISKIENLSNLHQLQMLELGSNRIRAIENI---DTLTNLESLFLGKNKITKLQN---LDA 228
Query: 121 CPTLIALTM 129
L L+M
Sbjct: 229 LTNLTVLSM 237
Score = 39.7 bits (91), Expect = 0.008
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Query: 40 LKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNL 99
L +E LQ+ ++LR S+N I I L++ KL LD+ N+IK + N + L L
Sbjct: 242 LTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENI---SHLTEL 298
Query: 100 KLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALD 155
+ +++DN ++ L +L + + P+ YR ++ ++ ++ +D
Sbjct: 299 QEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQID 354
Score = 35.4 bits (80), Expect = 0.16
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 40 LKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNL 99
+K +ENL+ SLR +N I I L++ +L LD+ N ++++ + L L
Sbjct: 110 IKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGV---DKLTRL 166
Query: 100 KLLYLHDNGFAKLKNI 115
K L+L +N +K++N+
Sbjct: 167 KKLFLVNNKISKIENL 182
Score = 33.1 bits (74), Expect = 0.79
Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 40 LKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNL 99
++++EN+ + +L N IT + L + L L + N++ + + L NL
Sbjct: 198 IRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQ---NLVNL 254
Query: 100 KLLYLHDNGFAKLKNI 115
+ LYL NG ++ +
Sbjct: 255 RELYLSHNGIEVIEGL 270
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 40.4 bits (93), Expect = 0.005
Identities = 70/307 (22%), Positives = 131/307 (42%), Gaps = 34/307 (11%)
Query: 324 KTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYTSGSLKNNAVLREKKQHFFPAYPQ 383
K + L++K +E + EIV +K + I +L + SL ++ P
Sbjct: 1557 KKYQRLLEKAREEQREIV-KKHEEDLHILHHRLELQADSSLNK---FKQTAWDLMKQSPT 1612
Query: 384 PIYTTHPKPIIKKDIRLERSMKEFFAPQRAGM-----KLRTFS-DIDKY--YTEQKKQEY 435
P+ P K IRL M++ A Q + KL+ S D+++ TE K +E+
Sbjct: 1613 PV------PTNKHFIRLAE-MEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEF 1665
Query: 436 HKEKVRVVAMAQVARERVRVAVNEH---LNQKKYATQKLIEENKETIQNSLRQVWQNRFN 492
K+++ + ++V+ V + L+Q + +Q L E + + + R N
Sbjct: 1666 ENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRN 1725
Query: 493 YLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIV 552
+E+ + + AL KEK QKA R L++ L E T + I + EA L + ++
Sbjct: 1726 LVERLKSQLAL--KEKQQKALSRALLE-LRAEMTAAAEERI-ISATSQKEAHLNVQQIVD 1781
Query: 553 KQ----KLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQDAKTKVA 608
+ K + E +NLLK + +++ ++ E ++ ++ Q A K+
Sbjct: 1782 RHTRELKTQVEDLNENLLKLKEALKT----SKNRENSLTDNLNDLNNELQKKQKAYNKIL 1837
Query: 609 IVKTNLD 615
K +D
Sbjct: 1838 REKEEID 1844
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/217 (20%), Positives = 92/217 (42%), Gaps = 19/217 (8%)
Query: 397 DIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVA 456
+++ ++KE +R +KL+ I ++ + KK E EK + +
Sbjct: 464 ELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILK 523
Query: 457 VNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERL 516
+ L + YA + I E ++ L V R E+ ++ KS +A L
Sbjct: 524 EKDELKTQLYAALQQI----ENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLEL 579
Query: 517 LVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQE 576
V+N +D + + E+ LK++S I Q + + + + E+KK ++Q+
Sbjct: 580 EVKN-------------SLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQD 626
Query: 577 IYKRHCEEKFVMDMIAF--EKACERLQDAKTKVAIVK 611
K ++ + D+ A + A + ++ + K A++K
Sbjct: 627 KAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLK 663
Score = 33.5 bits (75), Expect = 0.60
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 14/129 (10%)
Query: 494 LEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVK 553
L++ E++ LK K+Q++ + +++ ER L + + KN +LKEK +
Sbjct: 471 LKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKT 530
Query: 554 QKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQDAKTKVAIVKTN 613
Q A + +NL KE+ V + KR +E+ E+L+D K+ A +
Sbjct: 531 QLYAALQQIENLRKELNDV----LTKRALQEE------ELHSKEEKLRDIKSHQA----D 576
Query: 614 LDFKVPNGL 622
L+ +V N L
Sbjct: 577 LELEVKNSL 585
Score = 30.4 bits (67), Expect = 5.1
Identities = 52/279 (18%), Positives = 108/279 (38%), Gaps = 21/279 (7%)
Query: 297 LKNSSEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKL 356
LK +E R+ + + + +K K ++K E+ DE+ + K
Sbjct: 471 LKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKT 530
Query: 357 PIYTSGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMK 416
+Y + L+ LR++ H K +DI+ +A ++
Sbjct: 531 QLYAA--LQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIK----------SHQADLE 578
Query: 417 LRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENK 476
L + +D T + + K++ ++ + +V + + + E + KL+E +
Sbjct: 579 LEVKNSLD---TIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEM-Q 634
Query: 477 ETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKID 536
E+I++ L + + N L + K LK+ S ++ +E T LK++
Sbjct: 635 ESIKD-LSAIRADLANKLAEEERAKKAVLKDLSDLTAQA----KSRDEETATIITQLKLE 689
Query: 537 RLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQ 575
R + S + K K E+ + L+K KK +S+
Sbjct: 690 RDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSE 728
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 40.4 bits (93), Expect = 0.005
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 429 EQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQ 488
+Q+ QEY + + +V Q+ ER++ N + + L+ + K + L Q +
Sbjct: 541 QQELQEYQNKLIYLVPEKQLLNERIK---NMQFSNTPDSGVSLLHK-KSLEKEELCQRLK 596
Query: 489 NRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEK 548
+ + LEK K L E ++ ++ N + L L KI R + E K
Sbjct: 597 EQLDALEKETASK---LSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERKRL 653
Query: 549 SLIVKQKL------KAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQ 601
L+ K+KL KA++ ++NL KE + +E KR EEK + E+ E Q
Sbjct: 654 ELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQ 712
>gi|7706093 toll-like receptor 7 [Homo sapiens]
Length = 1049
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/70 (41%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 44 ENLQSCI-SLRVCIFSNNFITDI--HPLQSCIKLIKLDLHGNQIKSLPNTKF-WNGLKNL 99
E L +C SL+ I NN I + + LQ +L LDL N+I+ + T F N L NL
Sbjct: 716 ERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNL 775
Query: 100 KLLYLHDNGF 109
K+L LH N F
Sbjct: 776 KMLLLHHNRF 785
>gi|21687175 leucine rich transmembrane and 0-methyltransferase
domain containing isoform 1 [Homo sapiens]
Length = 192
Score = 40.0 bits (92), Expect = 0.006
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 14/108 (12%)
Query: 58 SNNFITDIHP--------LQSCIKLIKLDLHGNQIKSLPN--TKFWNGLKNLKLLYLHDN 107
+NN + D+ L+ L +DL N + S+ T F+N L +LYLH N
Sbjct: 57 NNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFN----LSVLYLHGN 112
Query: 108 GFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALD 155
+L + L+ P L +LT+ P+ +KGYR ++ ++ + D
Sbjct: 113 SIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFD 160
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/161 (23%), Positives = 78/161 (48%), Gaps = 19/161 (11%)
Query: 416 KLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEEN 475
K ++++K E +K E K + +A +Q A+E+ V + + + +K+I++
Sbjct: 926 KKEVINEVEKAPKELRK-ELMKRRKEELAQSQHAQEQE--FVQKQQQELDGSLKKIIQQQ 982
Query: 476 KETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKI 535
K + N R+ N+ L +ARE L+E+ + +LL Q L ++ + LLK
Sbjct: 983 KAELANIERECLNNK-QQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLK- 1040
Query: 536 DRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQE 576
++E K+ + ++Y + L++E+K ++QE
Sbjct: 1041 ----RHE----------KETEQMQRYNQRLIEELKNRQTQE 1067
Score = 38.1 bits (87), Expect = 0.024
Identities = 57/226 (25%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 431 KKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETI---QNSLRQVW 487
KK++Y +E + + ER+ EH N+ + +++ E ++ + QN L+
Sbjct: 870 KKRQYDQEIENLEKQQKQTIERLE---QEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRK 926
Query: 488 QNRFNYLEKARE--RKALFLKEK-----SQKASERLLVQN-------------------- 520
+ N +EKA + RK L + K SQ A E+ VQ
Sbjct: 927 KEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAEL 986
Query: 521 -------LNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKY--RKNLLKEMKK 571
LNN++ L+ I LE E L+EK ++KQ+LK + + R LLK +K
Sbjct: 987 ANIERECLNNKQQLMRAREAAIWELE--ERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEK 1044
Query: 572 VRSQ-EIYKRHCEEKFVMDMIAFEKACERLQ--DAKTKVAIVKTNL 614
Q + Y + E+ ++Q +AKT++A+ K +L
Sbjct: 1045 ETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSL 1090
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,492,538
Number of Sequences: 37866
Number of extensions: 1005982
Number of successful extensions: 4131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 305
Number of HSP's that attempted gapping in prelim test: 3610
Number of HSP's gapped (non-prelim): 692
length of query: 624
length of database: 18,247,518
effective HSP length: 108
effective length of query: 516
effective length of database: 14,157,990
effective search space: 7305522840
effective search space used: 7305522840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.