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Search of human proteins with 156938257
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
(1372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156938257 leucine rich repeat containing 16B [Homo sapiens] 2767 0.0
gi|63054866 leucine rich repeat containing 16A [Homo sapiens] 853 0.0
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain... 733 0.0
gi|118918429 NOD3 protein [Homo sapiens] 94 7e-19
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 67 9e-11
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 63 2e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 62 4e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 5e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 61 6e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 61 6e-09
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 60 1e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 60 1e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 60 1e-08
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 59 2e-08
gi|55750053 atrophin-1 [Homo sapiens] 59 2e-08
gi|55750041 atrophin-1 [Homo sapiens] 59 2e-08
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 59 4e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 58 7e-08
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 57 1e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 57 1e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 57 2e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 57 2e-07
gi|18959210 WIRE protein [Homo sapiens] 57 2e-07
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 56 2e-07
gi|168986655 hypothetical protein LOC145497 [Homo sapiens] 56 2e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 56 3e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 54 8e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 54 8e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 54 8e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 8e-07
>gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
Length = 1372
Score = 2767 bits (7173), Expect = 0.0
Identities = 1372/1372 (100%), Positives = 1372/1372 (100%)
Query: 1 MAKPSVELTRELQDSIRRCLSQGAVLQQHHVKLETKPKKFEDRVLALTSWRLHLFLLKVP 60
MAKPSVELTRELQDSIRRCLSQGAVLQQHHVKLETKPKKFEDRVLALTSWRLHLFLLKVP
Sbjct: 1 MAKPSVELTRELQDSIRRCLSQGAVLQQHHVKLETKPKKFEDRVLALTSWRLHLFLLKVP 60
Query: 61 AKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGP 120
AKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGP
Sbjct: 61 AKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGP 120
Query: 121 GCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVD 180
GCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVD
Sbjct: 121 GCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVD 180
Query: 181 TIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLS 240
TIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLS
Sbjct: 181 TIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLS 240
Query: 241 KSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCF 300
KSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCF
Sbjct: 241 KSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCF 300
Query: 301 PSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFL 360
PSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFL
Sbjct: 301 PSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFL 360
Query: 361 AQPNALVHLDLSGTDCVIDLLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFS 420
AQPNALVHLDLSGTDCVIDLLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFS
Sbjct: 361 AQPNALVHLDLSGTDCVIDLLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFS 420
Query: 421 SAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAV 480
SAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAV
Sbjct: 421 SAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAV 480
Query: 481 TCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEE 540
TCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEE
Sbjct: 481 TCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEE 540
Query: 541 DCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLR 600
DCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLR
Sbjct: 541 DCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLR 600
Query: 601 TILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLV 660
TILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLV
Sbjct: 601 TILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLV 660
Query: 661 RNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARD 720
RNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARD
Sbjct: 661 RNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARD 720
Query: 721 LIKDAKNSRALFPSLYELGHVLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQE 780
LIKDAKNSRALFPSLYELGHVLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQE
Sbjct: 721 LIKDAKNSRALFPSLYELGHVLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQE 780
Query: 781 LCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTSS 840
LCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTSS
Sbjct: 781 LCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTSS 840
Query: 841 IVDEILQELYHSHKSLARHLTQLRTLSDPPGCPGQGQDLSSRGRGRNHDHEETTDDELGT 900
IVDEILQELYHSHKSLARHLTQLRTLSDPPGCPGQGQDLSSRGRGRNHDHEETTDDELGT
Sbjct: 841 IVDEILQELYHSHKSLARHLTQLRTLSDPPGCPGQGQDLSSRGRGRNHDHEETTDDELGT 900
Query: 901 NIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEG 960
NIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEG
Sbjct: 901 NIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEG 960
Query: 961 LSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRR 1020
LSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRR
Sbjct: 961 LSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRR 1020
Query: 1021 VLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP 1080
VLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP
Sbjct: 1021 VLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP 1080
Query: 1081 PPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG 1140
PPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG
Sbjct: 1081 PPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG 1140
Query: 1141 EGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPG 1200
EGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPG
Sbjct: 1141 EGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPG 1200
Query: 1201 SWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERT 1260
SWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERT
Sbjct: 1201 SWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERT 1260
Query: 1261 LPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQD 1320
LPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQD
Sbjct: 1261 LPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQD 1320
Query: 1321 QEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
QEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD
Sbjct: 1321 QEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
>gi|63054866 leucine rich repeat containing 16A [Homo sapiens]
Length = 1326
Score = 853 bits (2203), Expect = 0.0
Identities = 543/1352 (40%), Positives = 782/1352 (57%), Gaps = 73/1352 (5%)
Query: 1 MAKPSVELTRELQDSIRRCLSQGAVLQ-QHHVKLETKPKKFEDRVLALTSWRLHLFLLKV 59
M + S ++ REL +SI+ + + + + VKLE K K E++VL LTS R L ++
Sbjct: 1 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI 60
Query: 60 PAKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPG 119
P K+E +F+ LEI Q++VETE+ +SM++ S E V +V H+ + L K+ PG
Sbjct: 61 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG 120
Query: 120 --PGCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQW 177
P ++++ + + E ++ T CGGFS+ YA +CD+ G REEVQW
Sbjct: 121 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW 180
Query: 178 DVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLH 237
DVDTIY +D RE NL DFSHL+ RDL ++AAL YNQWFTKL KDL+L ++V EQ+L
Sbjct: 181 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR 240
Query: 238 TLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQL 297
+S+S LEELVL+NAGL+TDF QKLA N + LH + L+ NP+ED+G SLS Q
Sbjct: 241 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF 300
Query: 298 LCFPSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALY 357
P GL L L+KT++SP+G+ +L Q+ ANP AS+L +LDLS N +L D+ + +Y
Sbjct: 301 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGN--VLRGDDLSHMY 358
Query: 358 SFLAQPNALVHLDLSGTDCVIDLLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQ 417
+FLAQPNA+VHLDLS T+C +D++ GALL GC +L LNL+R SHRKG+E PP+FKQ
Sbjct: 359 NFLAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQ 418
Query: 418 FFSSAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQL 477
FFSS+ L H+NLS TKL E L+ALL GL+ N +L + LDLS+CELRS GAQ L+ +
Sbjct: 419 FFSSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCI 478
Query: 478 GAVTCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFN-VKAKTLEEILHKLVQL 536
+ + SLD+SDNG +SDL TL+ L KN+S++HL LGKNFN +K+K L +L LVQ+
Sbjct: 479 AEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQM 538
Query: 537 IQEEDCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQIN 596
IQ+E+ LQSLS+ADS+LK +I+INALGSNT L KVD+SGNGM D+GAKML+KALQIN
Sbjct: 539 IQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQIN 598
Query: 597 SSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQ 656
+ LRT++WD+NN +A GF DIA A+E N+TLRFM P+ D SQA ++ PE+TED QKI+
Sbjct: 599 TKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIE 658
Query: 657 WCLVRNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELL 716
L+RN+ ++ QEQA+RLQQG+VTS+ +QM+ R+C +VQ+ + +LR C + +Q++L
Sbjct: 659 NYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLK 718
Query: 717 YARDLIKDAKNSRALFPSLYELGHVL------ANDGPVRQRLESVASEVSKAVDKELQVI 770
A L++DAKNS+ L P+LY +G P+++ LES+A EV++ VD++L+ +
Sbjct: 719 SAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKAL 778
Query: 771 LESMVSLTQELCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVK 830
LESMV + LCP M+ A ++ E++++PR F++ LLEQ+G DI NK+ EVK
Sbjct: 779 LESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVK 838
Query: 831 LSVVTYLTSSIVDEILQELYHSHKSLARHLTQL-RTLSDPPGCPGQGQDLSSRGRGRNHD 889
L+V ++L+ IVDEIL L H H LA H ++ +TL + + R
Sbjct: 839 LTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRS-IIT 897
Query: 890 HEETTDDELGTNIDT-MAIKKQKR----CRKIRPVSAFISGSPQDMESQLGNLGI----P 940
EE T+ E ++DT M K KR R +RPVS D++ L + I P
Sbjct: 898 VEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFE-MEFDLDKALEEVPIHIEDP 956
Query: 941 PGWFSGLGGSQPTASGSWEGLSELPT-HGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPG- 998
P F L + +SG +SELP+ G KL H T+ RP+ R P + ++ A
Sbjct: 957 P--FPSL-RQEKRSSGF---ISELPSEEGKKLEHFTKLRPK--RNKKQQPTQAAVCAANI 1008
Query: 999 ---TRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRR-- 1053
++NG+ R+DEG+++FF+++V + S T + L+E ++ R+
Sbjct: 1009 VSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSS 1068
Query: 1054 GLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPE-- 1111
G + + RS K +R P T L+ P P SPP P + + E
Sbjct: 1069 GFLNLIKSRS-KSER----PPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERI 1123
Query: 1112 EESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFD 1171
EE F +G ++G + P G +V G L +AK
Sbjct: 1124 EEIKTPDSFEESQG----EEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAK----Q 1175
Query: 1172 GKREGPGPDQ-----EGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAM-------R 1219
R G G + E +A + RSS P S P P QS KPS +A R
Sbjct: 1176 ENRFGLGTPEKNTKAEPKAEAGSRSRSSSST-PTS--PKPLLQSPKPSLAARPVIPQKPR 1232
Query: 1220 RAEATWHIAEE-SAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPP 1278
A I + S+P + P ++E++G P+ P+ Q+ + W
Sbjct: 1233 TASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQ---PSPRTFSQEVSRRSWGQ 1289
Query: 1279 KPVAVPRGRQPPQEPGVREEAEAGDAAPGVNK 1310
+ +Q + +++ D+ K
Sbjct: 1290 QAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEK 1321
>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain and
proline-rich containing [Homo sapiens]
Length = 1435
Score = 733 bits (1893), Expect = 0.0
Identities = 524/1442 (36%), Positives = 748/1442 (51%), Gaps = 162/1442 (11%)
Query: 41 EDRVLALTSWRLHLFLLK-VPAKVESSFNVLEIRAF---NTLSQNQILVETERGMVSMRL 96
++ VLAL WR +L +P +V+ +F+ LE++A T Q +E+ R +V +
Sbjct: 40 QNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQAMALQETPPQVTFELESLRELV-LEF 98
Query: 97 PSAESVDQVTRHVSSALSKVCPGP--GCLIRRGNADTPEGPRDTSPNSETSTSTTH-SVC 153
P +++Q+ +HV++A+ KV P G L RR TP S S ST S C
Sbjct: 99 PGVAALEQLAQHVAAAIKKVFPRSTLGKLFRR---PTPASMLARLERSSPSESTDPCSPC 155
Query: 154 GGFSETYAALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAY 213
GGF ETY ALCDYNG REE+QWDVDTIYH + R F+L DFSHL SRDLAL VAAL+Y
Sbjct: 156 GGFLETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSY 215
Query: 214 NQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSC 273
N WF L C D++L EV EQ+LH +S+S LEELVL+ L+ DFV++LA + S
Sbjct: 216 NLWFRCLSCVDMKLSLEVSEQILHMMSQSSHLEELVLETCSLRGDFVRRLAQALAGHSSS 275
Query: 274 VLHALTLSHNPIEDKGFLSLSQQLLCFPSGLTKLCLAKTAISPRGLQALGQTFGANPAFA 333
L L+L+ N ++D+G +LS+ L P L +L LA+T ++PRG++ALG+ N AF
Sbjct: 276 GLRELSLAGNLLDDRGMTALSRHLERCPGALRRLSLAQTGLTPRGMRALGRALATNAAFD 335
Query: 334 SSLRYLDLSKNPGLL-ATDEANALYSFLAQPNALVHLDLSGTDCVIDLLLG--------- 383
S+L +LDLS NPG L A++++ LYSFL++PN L L+L+GTD +D + G
Sbjct: 336 STLTHLDLSGNPGALGASEDSGGLYSFLSRPNVLSFLNLAGTDTALDTVRGCSVGGWMTG 395
Query: 384 ---------------------------ALLHGCCSHLTYLNLARNSCSHRKGREAPPAFK 416
A+ GCC+ LT+L+ +RN S K R AP A +
Sbjct: 396 RADWRAGRGGLGPPAGVANSLPPQLFAAVSRGCCTSLTHLDASRNVFSRTKSRAAPAALQ 455
Query: 417 QFFSSAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQ 476
F S A TL H+ L+ KLP +ALRALL GL+LN+HL DLHLDLS+CELRSAGAQ +Q+
Sbjct: 456 LFLSRARTLRHLGLAGCKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDL 515
Query: 477 LGAVTCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAK-TLEEILHKLVQ 535
+ V SLDL+DNGF SD++TLV A+G+++SL+H+ LG+NFNV+ K TL+++LH++VQ
Sbjct: 516 VCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQ 575
Query: 536 LIQEEDCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQI 595
L+Q++DC LQSLSVA+SRLKL S+L+ AL +N L +D+SGN M D GAK+L+KAL++
Sbjct: 576 LMQDDDCPLQSLSVAESRLKLGASVLLRALATNPNLTALDISGNAMGDAGAKLLAKALRV 635
Query: 596 NSSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKI 655
NS LR+++WDRN+TSALG LD+A+ALE NH+L+ M P++D++QA RS PE T +I
Sbjct: 636 NSRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQI 695
Query: 656 QWCLVRNNHSQTCPQEQAFRLQQ-GLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDE 714
Q CL+RNN + + RLQ GLV+ +EQ + LC VQE V L +
Sbjct: 696 QACLLRNNRADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAA 755
Query: 715 LLYARDLIKDAKNSRALFPSLYELGHVLANDGPVRQRLESVASEVSKAVDKELQVILESM 774
+ A D I++A S ++ P LYE G ++ + Q+LE + +V + +++Q ++
Sbjct: 756 VRQAEDAIQNANFSLSILPILYEAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQDFTQAT 815
Query: 775 VSLTQELCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVV 834
+ + LCP ++ + ++ +A +P L EQ QD +L +++LS+
Sbjct: 816 LDTARSLCPQMLQGSSWREQLEGVLAGSRGLPE-----LLPEQLLQDAFTRLRDMRLSIT 870
Query: 835 TYLTSSIVDEILQELYHSHKSLARHLTQLRTLSDPPGCP---GQGQDLSSRGRGRNHDHE 891
L SIV + L L + L L Q T++ PP P G L G
Sbjct: 871 GTLAESIVAQALAGLSAARDQLVESLAQQATVTMPPALPAPDGGEPSLLEPGELEGLFFP 930
Query: 892 ETTDDELGTNIDTMAIKKQKRCRKIRPV----SAFISGSPQDMESQLGNLGIPPGWFSGL 947
E ++E + D+ K + + V SA P+ + G P S
Sbjct: 931 EEKEEEKEKD-DSPPQKWPELSHGLHLVPFIHSAAEEAEPEPELAAPGEDAEPQAGPSAR 989
Query: 948 GGSQPTASGSWEG---LSELPTHGYKLRHQTQGRPRPPRT--TPPGPGRPSMPAPGTRQE 1002
G P A G G +LP G LRH T+ RPRP R P PG P +P ++
Sbjct: 990 GSPSPAAPGPPAGPLPRMDLPLAGQPLRHPTRARPRPRRQHHHRPPPGGPQVPPALPQEG 1049
Query: 1003 NGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPR 1062
NG++ R+DEG+E+FFS+R++++ + G P+P +K+ LF F++PR
Sbjct: 1050 NGLSARVDEGVEEFFSKRLIQQDRLWAPEEDPATEG-GATPVPRTLRKKLGTLFAFKKPR 1108
Query: 1063 SFKGDR-----GPGS------PTTGLLLPPPPPPPPTQE------SPPSPDPPSLG---- 1101
S +G R PG+ T G LL PP P +E SPDP
Sbjct: 1109 STRGPRTDLETSPGAAPRTRKTTFGDLLRPPTRPSRGEELGGAEGDTSSPDPAGRSRPRY 1168
Query: 1102 NNSSPCWS----PEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVH-- 1155
S +S P EE + L G P RR + E GE AP Q+ +V
Sbjct: 1169 TRDSKAYSMILLPAEEEATL-----GARPDKRRPL-----ERGETELAPSFEQRVQVMLQ 1218
Query: 1156 --GVA--LPGLERAKGWSFDGKREGPGPD---QEGSTQAWQ---KRRSSDDAGPGSWKPP 1205
GV+ G E + S DG+ + G D + ST+A K R+ + S +P
Sbjct: 1219 RIGVSRGSGGAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPG 1278
Query: 1206 P----PPQSTKPSFSAMRRAEAT---WHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPE 1258
P P +T + AE W + P QSPSP + G
Sbjct: 1279 PGSQGPESATWKTLGQQLNAELRSRGWGQQDGPGPPSPGQSPSPCRTSPSPDSLG----- 1333
Query: 1259 RTLPARNAKLQDPALAP------WPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPR 1312
LP +DP L P P+P++ R E ++ AE +P
Sbjct: 1334 --LP------EDPCLGPRNEDGQLRPRPLSAGRRAVSVHEDQLQAPAE---------RPL 1376
Query: 1313 LRLSSQQDQEEPEVQGPPDP----GRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSE 1368
S + P+++ PP P G T PL P+ T + R PP P
Sbjct: 1377 RLQRSPVLKRRPKLEAPPSPSLGSGLGTEPLPPQPTEPSS-------PERSPPSPATDQR 1429
Query: 1369 PG 1370
G
Sbjct: 1430 GG 1431
Score = 37.4 bits (85), Expect = 0.100
Identities = 51/192 (26%), Positives = 80/192 (41%), Gaps = 27/192 (14%)
Query: 927 PQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGL-----SELPTHGYKLRHQTQGRPRP 981
P ++S+ ++ P G GSQ S +W+ L +EL + G+ + G P P
Sbjct: 1259 PISIKSRTHSVSADPSCRPG-PGSQGPESATWKTLGQQLNAELRSRGWG-QQDGPGPPSP 1316
Query: 982 PRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSE 1041
++ P PS + G ++ + R ++G ++ S R +V +
Sbjct: 1317 GQSPSPCRTSPSPDSLGLPEDPCLGPRNEDG-------QLRPRPLSAGRRAVSVHEDQLQ 1369
Query: 1042 APLP-PLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPP-PPPPTQ-----ESPPS 1094
AP PL+ +R L RRP+ P SP+ G L P PP PT+ SPPS
Sbjct: 1370 APAERPLRLQRSPVLK--RRPKL----EAPPSPSLGSGLGTEPLPPQPTEPSSPERSPPS 1423
Query: 1095 PDPPSLGNNSSP 1106
P G +P
Sbjct: 1424 PATDQRGGGPNP 1435
>gi|118918429 NOD3 protein [Homo sapiens]
Length = 1065
Score = 94.4 bits (233), Expect = 7e-19
Identities = 122/447 (27%), Positives = 189/447 (42%), Gaps = 63/447 (14%)
Query: 197 SHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLK 256
S L +D + +LA NQ K G++ L + +L + SL L L +
Sbjct: 659 SVLSGKDCRIQKISLAENQISNK--------GAKALAR---SLLVNRSLTSLDLRGNSIG 707
Query: 257 TDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCFPSGLTKLCLAKTAISP 316
+ LA N + L +L+L N + D G S+++ L + L+ L L K +I P
Sbjct: 708 PQGAKALADALKINRT--LTSLSLQGNTVRDDGARSMAEALASNRT-LSMLHLQKNSIGP 764
Query: 317 RGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFLAQPNALVHLDLSGTDC 376
G Q + N SL+ L S N + A AL L L LDL ++
Sbjct: 765 MGAQRMADALKQN----RSLKELMFSSNS--IGDGGAKALAEALKVNQGLESLDLQ-SNS 817
Query: 377 VIDLLLGALLHGCCSHLTYLNLA--RNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATK 434
+ D + AL+ C++ T L+L+ NS S E A + TL +++L+A
Sbjct: 818 ISDAGVAALMGALCTNQTLLSLSLRENSISP----EGAQAIAHALCANSTLKNLDLTANL 873
Query: 435 LPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGFD 494
L + RA+ + N L+ LHL + +++ AQAL + L + SLDL +N
Sbjct: 874 LHDQGARAIAVAVRENRTLTSLHLQWNF--IQAGAAQALGQALQLNRSLTSLDLQENAIG 931
Query: 495 SD-LLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSR 553
D + AL N +L L+L Q S+ S
Sbjct: 932 DDGACAVARALKVNTALTALYL-----------------------------QVASIGASG 962
Query: 554 LKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALG 613
+ +L AL N L +DL GN + GAK L+ AL++NSSLR + N+ G
Sbjct: 963 AQ----VLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDG 1018
Query: 614 FLDIARALESNHTLRFMSFPVSDISQA 640
+ IA AL NH L+ ++ + I +
Sbjct: 1019 AICIATALSGNHRLQHINLQGNHIGDS 1045
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 67.4 bits (163), Expect = 9e-11
Identities = 109/459 (23%), Positives = 146/459 (31%), Gaps = 118/459 (25%)
Query: 921 AFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPR 980
+ I+G+PQ G PP GG++P S G + P Q +P+
Sbjct: 30 SLIAGNPQ---------GAPPQ-----GGNKPQGPPSPPGKPQGPPP------QGGNQPQ 69
Query: 981 PPRTTPPGPGRPSMPAP-GTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGL 1039
P PP PG+P P P G + G PG
Sbjct: 70 GP---PPPPGKPQGPPPQGGNKPQGPPP-----------------------------PGK 97
Query: 1040 SEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPP------ 1093
+ P P K R PRS G P G PPPPP + PP
Sbjct: 98 PQGPPPQGDKSRS--------PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149
Query: 1094 --SPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQ 1151
P PP P + SS P G +GP G++P P PG Q
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPP-GKPQGPP-----PQGGNQPQGPPPPPGKPQG 203
Query: 1152 PRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST 1211
P G P +G GK +GP P + +Q S + PG + PPP
Sbjct: 204 PPPQGGNKP-----QGPPPPGKPQGPPPQGDNKSQ-------SARSPPGKPQGPPPQGGN 251
Query: 1212 KPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDP 1271
+P P Q P P + + P+ P +K +
Sbjct: 252 QPQ--------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297
Query: 1272 ALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPD 1331
P P+ P+G PQ P G G NKP QGPP
Sbjct: 298 RSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---------------QGPPP 341
Query: 1332 PGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPG 1370
PG+ P P+ +++S + PP G + G
Sbjct: 342 PGKPQGP-PPQGGSKSRSARSPPGKPQGPPQQEGNNPQG 379
Score = 51.6 bits (122), Expect = 5e-06
Identities = 81/308 (26%), Positives = 107/308 (34%), Gaps = 50/308 (16%)
Query: 925 GSPQDMESQLGNLGI---PPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRP 981
G PQ Q GN PPG G P G + S G QG +P
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQG-----PPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 982 PRTTPPGPGRPSMPAP--GTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGL 1039
+ PP PG+P P P G + + +G + +S+ P PG
Sbjct: 192 -QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK--SQSARSP-------PGK 241
Query: 1040 SEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPS 1099
+ P PP + +G P G + G P G P PPPP + PP P
Sbjct: 242 PQGP-PPQGGNQPQG------PPPPPG-KPQGPPPQGGNKPQGPPPPGKPQGPP----PQ 289
Query: 1100 LGNNSSPCWSPEEESSLLPGFGG----GRGPSFRRKMGT--EGSEPGEGGPAPGTAQQPR 1153
G+ S SP + P GG G P + G +G +G P PG Q P
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 349
Query: 1154 VHGVAL-------PGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPP 1206
G + PG + +GP P G+ Q Q + G PP
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG-----PPR 404
Query: 1207 PPQSTKPS 1214
PPQ +PS
Sbjct: 405 PPQGGRPS 412
Score = 37.4 bits (85), Expect = 0.100
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 36/143 (25%)
Query: 1227 IAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG 1286
+++E +P+ +P A G + +G P+ K Q P PP+ P+G
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGP-------PSPPGKPQGP-----PPQGGNQPQG 70
Query: 1287 RQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRR 1346
PP PG + G G NKP QGPP PG+ P P + +
Sbjct: 71 --PPPPPGKPQ----GPPPQGGNKP---------------QGPPPPGKPQGP--PPQGDK 107
Query: 1347 AQSCDKLEPDRRRPPDPTGTSEP 1369
++S + P + + P P G ++P
Sbjct: 108 SRS-PRSPPGKPQGPPPQGGNQP 129
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 62.8 bits (151), Expect = 2e-09
Identities = 114/483 (23%), Positives = 169/483 (34%), Gaps = 125/483 (25%)
Query: 976 QGRPRPPRTTPPGPGRP-----------SMPAPGTRQENGMATRLDEGLEDFFSRRVLEE 1024
+G P PP+T PP P P S P P R + + + GLE +R
Sbjct: 827 RGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLE---ARLGAGA 883
Query: 1025 SSSYPRTLRTVRPGLSEAPLP-PLQKKRRRGLFHFR--RPRSFKGDRGPGSPTTGLLLPP 1081
+ Y PG + PLP P ++KR R + + P S R P + T
Sbjct: 884 AGLY-------EPGAALGPLPYPERQKRARSMIILQDSAPESGDAPRPPPAAT------- 929
Query: 1082 PPPPPPTQESPPSPDPP--SLGNNSSPCWSP-------------------EEESSLLPGF 1120
PP P + PP PD P +LG S+ ++P +E ++L G
Sbjct: 930 PPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGS 989
Query: 1121 GGGRGPSFRRKMGT-------------EGSEPGEGGPAPGTAQQPRVH------------ 1155
G G SF R+ G PG PG A+ R+
Sbjct: 990 PGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVG 1049
Query: 1156 -------GVALPGLERAKGWSFDGKREGPGPDQ------EGSTQAWQKRRSSDDAGPG-- 1200
G LP L+ ++ S D + G GP A + S GP
Sbjct: 1050 AIEGSAPGADLPSLQPSR--SIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGS 1107
Query: 1201 ------SWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
+ KP P + +A RA A+ AP+ +SP+P + ++ G
Sbjct: 1108 TFIHPLTGKPLDPSSPLALALAARERALAS------QAPS---RSPTPV-HSPDADRPGP 1157
Query: 1255 LFPE-RTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRL 1313
LF + + L PA +P P + VP R+ + P REE ++ + + L
Sbjct: 1158 LFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVP--REERKSPEDKKSMILSVL 1215
Query: 1314 RLSSQQ------------DQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPP 1361
S Q+ QE + G + T L P + A + L R +PP
Sbjct: 1216 DTSLQRPAGLIVVHATSNGQEPSRLGGAEEERPGTPELAPAPMQSAAVAEPLPSPRAQPP 1275
Query: 1362 DPT 1364
T
Sbjct: 1276 GGT 1278
Score = 34.3 bits (77), Expect = 0.84
Identities = 78/330 (23%), Positives = 105/330 (31%), Gaps = 49/330 (14%)
Query: 1013 LEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGD----R 1068
+ F R+ L P +LR P + ++ L R PRS
Sbjct: 770 ISSLFERQGLPGPEKLPGSLRKGIPRTKSVG----EDEKLASLLEGRFPRSTSMQDPVRE 825
Query: 1069 GPGSPTTGLLLPPPPPPPPTQESPPSP---DPPSLGNNSSPCWSPEEESSLLPGFGGGRG 1125
G G P PPPPP P +S P P PP G SS PG G
Sbjct: 826 GRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTV-----RSSFKPGLEARLG 880
Query: 1126 PSFRRKMGTEG-SEPGEG-GPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEG 1183
G G EPG GP P +Q R + + L+ + S D R P
Sbjct: 881 ------AGAAGLYEPGAALGPLPYPERQKRARSMII--LQDSAPESGDAPRPPP-----A 927
Query: 1184 STQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSA---------MRRAEATWHIAEESAPN 1234
+T + +R GP S P + +FSA R++ + E A
Sbjct: 928 ATPPERPKRRPRPPGPDS------PYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQE 981
Query: 1235 HSC---QSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQ 1291
+ SP P E T R P LA P P R + +
Sbjct: 982 RAALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRR 1041
Query: 1292 EPGVREEAEAGDAAPGVNKPRLRLSSQQDQ 1321
+APG + P L+ S D+
Sbjct: 1042 STVFLSVGAIEGSAPGADLPSLQPSRSIDE 1071
Score = 32.7 bits (73), Expect = 2.5
Identities = 69/266 (25%), Positives = 88/266 (33%), Gaps = 38/266 (14%)
Query: 1073 PTTG--LLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRR 1130
PT G LLLP P P PSLG P + + P G PS
Sbjct: 1078 PTAGRDLLLPSP-----VSALKPLVSGPSLG--------PSGSTFIHPLTGKPLDPSSPL 1124
Query: 1131 KMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGP------GPDQEGS 1184
+ E AP + P VH P +R D + P P
Sbjct: 1125 ALALAARERALASQAPSRSPTP-VHS---PDADRPGPLFVDVQARDPERGSLASPAFSPR 1180
Query: 1185 TQAW---QKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPS 1241
+ AW RR ++ K P +S S I + N Q PS
Sbjct: 1181 SPAWIPVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNG--QEPS 1238
Query: 1242 PASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQE-PGVREEAE 1300
EEE+ GT PE A +Q A+A P P A P G P PG E
Sbjct: 1239 RLG-GAEEERPGT--PELA----PAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEE 1291
Query: 1301 AGDAAPGVNKPRLRLSSQQDQEEPEV 1326
+ VN P +LSS ++ E+
Sbjct: 1292 EPELVFAVNLPPAQLSSSDEETREEL 1317
Score = 32.3 bits (72), Expect = 3.2
Identities = 59/230 (25%), Positives = 83/230 (36%), Gaps = 45/230 (19%)
Query: 1070 PGSPTTGLLLPPP-------PPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGG 1122
PG+P L P P P P + PP P G S EEE L+ F
Sbjct: 1248 PGTPE---LAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQG---SSEEEPELV--FAV 1299
Query: 1123 GRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQE 1182
P+ ++ + E E + R+ G+ P E A G GPGP
Sbjct: 1300 NLPPA---QLSSSDEETRE--------ELARI-GLVPPPEEFANGVLLATPLAGPGPSPT 1347
Query: 1183 GSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPS--FSAMRRAEATWHIAEESAPNHSCQSP 1240
S +G S +PPP P+S S A R+ + H+ S +
Sbjct: 1348 TVP--------SPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSSMS 1399
Query: 1241 SPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKP-VAVPRGRQP 1289
+ +S+ GE T F + L+ P P PPKP + P G+ P
Sbjct: 1400 TLSSESGELTDTHTSFAD----GHTFLLEKP---PVPPKPKLKSPLGKGP 1442
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 62.0 bits (149), Expect = 4e-09
Identities = 98/372 (26%), Positives = 126/372 (33%), Gaps = 101/372 (27%)
Query: 982 PRTTPPGPGRPSMPAP-GTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLS 1040
P+ PP PG+P P P G + G PG
Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPP-----------------------------PGKP 77
Query: 1041 EAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPD---- 1096
+ P P K R PRS G + G P G P PPPPP + P P
Sbjct: 78 QGPPPQGDKS--------RSPRSPPG-KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128
Query: 1097 ---PPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPR 1153
PP G P P+ + S P G+ P G G++P P PG Q P
Sbjct: 129 PQGPPPPGKPQGP--PPQGDKSRSPRSPPGK-PQGPPPQG--GNQPQGPPPPPGKPQGPP 183
Query: 1154 VHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKP 1213
G P +G GK +GP P + K RSS + PG + PPP +P
Sbjct: 184 PQGGKKP-----QGPPPPGKPQGPPPQGD-------KSRSS-QSPPGKPQGPPPQGGNQP 230
Query: 1214 SFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTL--PARNAKLQDP 1271
P Q P P G + +G P + PA+
Sbjct: 231 Q--------------GPPPPPGKPQGPPP---QGGNKPQGPPPPGKPQGPPAQGGSKSQS 273
Query: 1272 ALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEP--EVQGP 1329
A +P P KP + PPQ+ G + G P P QQ Q P + QGP
Sbjct: 274 ARSP-PGKP------QGPPQQEGNNPQ---GPPPPAGGNP------QQPQAPPAGQPQGP 317
Query: 1330 PDPGRRTAPLKP 1341
P P + P +P
Sbjct: 318 PRPPQGGRPSRP 329
Score = 58.2 bits (139), Expect = 5e-08
Identities = 69/280 (24%), Positives = 92/280 (32%), Gaps = 33/280 (11%)
Query: 1068 RGPGSPTTGLLLPPPPPPPPTQESPP--------SPDPPSLGNNSSPCWSPEEESSLLPG 1119
+GP SP G PPPPP + PP P PP P PG
Sbjct: 37 QGP-SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
Query: 1120 FGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGP 1179
G P G++P P PG Q P G R +G GK +GP P
Sbjct: 96 KPQGPPPQ-------GGNQPQGPPPPPGKPQGPPPQGG-----NRPQGPPPPGKPQGPPP 143
Query: 1180 --DQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSC 1237
D+ S ++ + G+ PPP KP + + + P
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK----PQGPPPPGKP 199
Query: 1238 QSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPW-----PPKPVAVPRGRQPPQE 1292
Q P P + P+ P + Q P P PP+ P+G PP +
Sbjct: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
Query: 1293 PGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDP 1332
P A+ G + P + QE QGPP P
Sbjct: 260 P-QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298
Score = 55.5 bits (132), Expect = 4e-07
Identities = 74/293 (25%), Positives = 92/293 (31%), Gaps = 67/293 (22%)
Query: 1080 PPPP-----PPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGT 1134
PPPP PPP P P PP P PG G P
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ------- 103
Query: 1135 EGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSS 1194
G++P P PG Q P G R +G GK +GP P + S S
Sbjct: 104 GGNQPQGPPPPPGKPQGPPPQGG-----NRPQGPPPPGKPQGPPPQGDKSR--------S 150
Query: 1195 DDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
+ PG + PPP +P P Q P P G ++ +G
Sbjct: 151 PRSPPGKPQGPPPQGGNQPQ--------------GPPPPPGKPQGPPP---QGGKKPQGP 193
Query: 1255 LFPERTL--PARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPR 1312
P + P + K + P P+ P+G PQ P G G NKP
Sbjct: 194 PPPGKPQGPPPQGDKSRSSQSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKP- 251
Query: 1313 LRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTG 1365
QGPP PG+ P AQ K + R P P G
Sbjct: 252 --------------QGPPPPGKPQGP-------PAQGGSKSQSARSPPGKPQG 283
Score = 33.5 bits (75), Expect = 1.4
Identities = 33/139 (23%), Positives = 52/139 (37%), Gaps = 16/139 (11%)
Query: 1227 IAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG 1286
+++E +P+ +P S G + +G P K Q P PP+ P+G
Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQGP-------PPPPGKPQGP-----PPQGGNKPQG 70
Query: 1287 RQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRR 1346
PP +P + GD + P + Q + QGPP P + P+ R
Sbjct: 71 PPPPGKP--QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128
Query: 1347 AQSCDKLEPDRRRPPDPTG 1365
Q P + + P P G
Sbjct: 129 PQG--PPPPGKPQGPPPQG 145
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 61.6 bits (148), Expect = 5e-09
Identities = 107/413 (25%), Positives = 140/413 (33%), Gaps = 95/413 (23%)
Query: 972 RHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSR------RVLEES 1025
R + R PPR PP P +P R+ A+ SR + + +
Sbjct: 319 RRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Query: 1026 SSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPP 1085
SS PR R + P S PP RRR RP PP PP
Sbjct: 379 SSPPRKTRRLSPSAS----PP----RRR-----HRPS-----------------PPATPP 408
Query: 1086 PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPA 1145
P T+ SP P N + + S+ PG G+ + GTE E +
Sbjct: 409 PKTRHSPT----PQQSNRTR-----KSRVSVSPGRTSGK---VTKHKGTEKRE------S 450
Query: 1146 PGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPP 1205
P A +PR V L E KG GK Q+ Q ++SS D+G S
Sbjct: 451 PSPAPKPRK--VELSESEEDKG----GKMAAADSVQQRRQYRRQNQQSSSDSGSSS---- 500
Query: 1206 PPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARN 1265
+ +P S ++ E +P+ S SPSP + E G R
Sbjct: 501 -SSEDERPKRSHVKNGEVGRR--RRHSPSRSA-SPSPRKRQKETSPRGR--------RRR 548
Query: 1266 AKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPE 1325
+ P P P PR R+ P P R + P R S + P
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTP---------SPPPRRRSPSPRRYSPP 599
Query: 1326 VQG----PPDPGRRTAPLKPKRTRRAQSCDKLEPDRRR---PPDPTGTSEPGT 1371
+Q P P RRTA P RRA P +RR P P S P T
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPS---PPPKRRVSHSPPPKQRSSPVT 649
Score = 60.5 bits (145), Expect = 1e-08
Identities = 97/419 (23%), Positives = 140/419 (33%), Gaps = 65/419 (15%)
Query: 962 SELPTHGY-KLRHQTQGRPRPPRTTPPGPGRPS---------MPAPGTRQENGMATRLDE 1011
S P+H + RH+++ R PR P RPS MP P + + R
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349
Query: 1012 GLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPG 1071
S SSS R+ PP + +R P
Sbjct: 350 RSSASLSGSSSSSSSSRSRS-------------PPKKPPKRTS--------------SPP 382
Query: 1072 SPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRK 1131
T L PP + SPP+ PP ++ +P S S + G +
Sbjct: 383 RKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH 442
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKR 1191
GTE E +P A +PR V L E KG GK Q+ Q +
Sbjct: 443 KGTEKRE------SPSPAPKPR--KVELSESEEDKG----GKMAAADSVQQRRQYRRQNQ 490
Query: 1192 RSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEK 1251
+SS D+G S + +P S ++ E +P+ S SPSP + E
Sbjct: 491 QSSSDSGSSS-----SSEDERPKRSHVKNGEVGRR--RRHSPSRSA-SPSPRKRQKETSP 542
Query: 1252 EGTLFPERT-LPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNK 1310
G + P R + PA P + P R+ P P R +P + +
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR 602
Query: 1311 PRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
R S + PP P RR +P P + R + S P ++R T P
Sbjct: 603 ---RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHS----PPPKQRSSPVTKRRSP 654
Score = 48.1 bits (113), Expect = 6e-05
Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 14/190 (7%)
Query: 1180 DQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQS 1239
D+E + +KR S + P P + + P +RR H +P H +S
Sbjct: 155 DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSP----VRRERKRSH---SRSPRHRTKS 207
Query: 1240 PSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAP---WPPKPVAVPRGRQPPQEPGVR 1296
SP+ ++EK L PE ++ + +Q+ PKP +P ++P E +
Sbjct: 208 RSPSPAPEKKEKTPEL-PEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSK 266
Query: 1297 EEAEAGDAAP---GVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKL 1353
+E E P +K R R S+ + R +P + RR S +
Sbjct: 267 KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 1354 EPDRRRPPDP 1363
P RR PP P
Sbjct: 327 TPPRRMPPPP 336
Score = 43.1 bits (100), Expect = 0.002
Identities = 75/331 (22%), Positives = 109/331 (32%), Gaps = 92/331 (27%)
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPD 1096
P S +P P +K+++ RR RS P P T P P PPP + P+P
Sbjct: 525 PSRSASPSP--RKRQKETSPRGRRRRS------PSPPPTRRRRSPSPAPPPRRRRTPTPP 576
Query: 1097 PPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHG 1156
P RR+ T P P+P P
Sbjct: 577 P-------------------------------RRR--TPSPPPRRRSPSPRRYSPP---- 599
Query: 1157 VALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFS 1216
++R R P P KRR++ PPPP + PS
Sbjct: 600 -----IQR---------RYSPSPP--------PKRRTAS-------PPPPPKRRASPSPP 630
Query: 1217 AMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPW 1276
RR + + S+P +SPS +S+ + E P N K P+ P
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN-KRHSPSPRPR 689
Query: 1277 PPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRT 1336
P+ + P PP G + + +P R+S PE P ++
Sbjct: 690 APQTSSSP----PPVRRGASSSPQRRQSPSPSTRPIRRVS-----RTPE----PKKIKKA 736
Query: 1337 APLKPKRTRRAQSCDKL----EPDRRRPPDP 1363
A P+ RR S + EP ++PP P
Sbjct: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767
Score = 41.6 bits (96), Expect = 0.005
Identities = 73/302 (24%), Positives = 92/302 (30%), Gaps = 51/302 (16%)
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRT-VR 1036
R R T+P G R S P TR RR + PR RT
Sbjct: 534 RKRQKETSPRGRRRRSPSPPPTR------------------RRRSPSPAPPPRRRRTPTP 575
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPP--------PPT 1088
P P PP RRR R + P P PPPPP PP
Sbjct: 576 PPRRRTPSPP---PRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 1089 QESPPSPDP------------PSLGNN----SSPCWSPEEESSLLPGFGGGRGPSFRRKM 1132
+ SP P PSL + SSP S E S P P R
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 1133 GTEGSEPGEGGPA--PGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQK 1190
+ P G + P Q P + + R K P P S +
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ---SVRRVSS 749
Query: 1191 RRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEE 1250
RS + + K PP P S S S + + +P S P + Q+G +
Sbjct: 750 SRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGK 809
Query: 1251 KE 1252
K+
Sbjct: 810 KK 811
Score = 37.7 bits (86), Expect = 0.076
Identities = 69/315 (21%), Positives = 105/315 (33%), Gaps = 48/315 (15%)
Query: 1014 EDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSP 1073
E+ S R E S PR ++ P P++++R+R H R PR R P
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRS--HSRSPRHRTKSRSPSPA 213
Query: 1074 TTGLLLPPPPPPPPTQESPPS-------------PDPPSLGNNSSPCWSPEEESSLLPGF 1120
P P P + PS P P + P SPE+ S
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP--SPEKNSKK---- 267
Query: 1121 GGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPD 1180
+ + R S +P + R H R++ S+ +R P P
Sbjct: 268 EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH--------RSRSRSYSPRRR-PSP- 317
Query: 1181 QEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSP 1240
+RR S + PPPP+ + RR ++ ++ S+ + S +S
Sbjct: 318 ---------RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSR 368
Query: 1241 SPASQ-----DGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGV 1295
SP + K L P + P R + PA PPK P +Q +
Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP--PPKTRHSPTPQQSNRTRKS 426
Query: 1296 REEAEAGDAAPGVNK 1310
R G + V K
Sbjct: 427 RVSVSPGRTSGKVTK 441
Score = 37.0 bits (84), Expect = 0.13
Identities = 51/184 (27%), Positives = 65/184 (35%), Gaps = 45/184 (24%)
Query: 949 GSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRT--TPPGPGRPSMPAPGTRQENGMA 1006
GS P+ S + E S P RH RPR P+T +PP R + +P RQ +
Sbjct: 663 GSSPSRS-TREARSPQPNK----RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
Query: 1007 TRLDEGLEDFFSRRVLEESSSYPRTLRTVRP-GLSEAPLPPLQKKRRRGLFHFRRPRSFK 1065
TR R RT P + +A P Q RR RS
Sbjct: 718 TR------------------PIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSSRSVS 754
Query: 1066 GDRGPGSPTTGLLLPPPPPPPPTQESPPSPD-----PPSLGNNSSPCWSPEEESSLLPGF 1120
G P + PP PP P Q PS + P + +P SP S
Sbjct: 755 GSPEPAAK------KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD---QE 805
Query: 1121 GGGR 1124
GGG+
Sbjct: 806 GGGK 809
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 61.2 bits (147), Expect = 6e-09
Identities = 95/435 (21%), Positives = 148/435 (34%), Gaps = 75/435 (17%)
Query: 959 EGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFS 1018
E E T K+ + QG+P PP +P P P +Q G +G S
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGI-IKPPLQQQPPKPIP-KQQGPGRDPLQQDGTPKSIS 240
Query: 1019 RRVLEESSSYPRTLRTVRPGLSEAPLP-----PLQKKRRRGLFHFRRPRSFKGDRGPGSP 1073
+ E+ S P G ++ P PLQ+ R P++ + D G
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR-------PQTKQADIVRGES 293
Query: 1074 TTGLLLPPPPPP--PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRK 1131
L P PP PT PP+ P + P P + S L
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL----------- 342
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKR 1191
PGT + P V PG + + GP + + Q ++
Sbjct: 343 -----------AQQPGTVKPP----VQPPGTTKPPA-------QPLGPAKPPAQQTGSEK 380
Query: 1192 RSSDDAGPGSWKPPP-----PPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQD 1246
SS+ GP + PP P Q P+ ++ +A++ ++P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 1247 GEEEKEGTLFPERTLPARNAKLQ-----DPALAPWPPKPVAVPRG--RQPPQEPGVREEA 1299
++ G + ++ P + + Q P+ P P KP G + PPQ+PG A
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG---SA 497
Query: 1300 EAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRR--AQSCDKLEPDR 1357
+ PG KP Q P P PG P + + + AQ +P
Sbjct: 498 KPPSQQPGSTKP------PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 1358 R---RPPDPTGTSEP 1369
+ +P TG+ +P
Sbjct: 552 QQSTKPVSQTGSGKP 566
Score = 40.8 bits (94), Expect = 0.009
Identities = 106/447 (23%), Positives = 153/447 (34%), Gaps = 94/447 (21%)
Query: 947 LGGSQPTA--SGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENG 1004
LG ++P A +GS + SE P G K Q G + P PGP +P GT
Sbjct: 366 LGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTP-AQQPGPAKPPTQQVGT----- 417
Query: 1005 MATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGL---SEAPLPPLQKKRRRGLFHFRRP 1061
P+ L +PGL ++AP P ++ G
Sbjct: 418 ------------------------PKPLAQ-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 1062 RSFKG-----DRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSL 1116
++ G GP P + L P P PPP Q P P P G+ P P
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP------ 504
Query: 1117 LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREG 1176
G + P ++ G P + G +QQP G A P ++ ++
Sbjct: 505 ----GSTKPPP--QQPGPAKPSPQQPGSTKPPSQQP---GSAKPSAQQPSPAKPSAQQST 555
Query: 1177 PGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPN-- 1234
Q GS + Q S A K PP K E H+ E++ N
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSA-----KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 1235 HSCQ---------SPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPV---- 1281
CQ +P+P + +E +R L A + PV
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS 670
Query: 1282 AVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKP 1341
AV + PQ+ ++ DAAP K L + + + P V+ P G +A K
Sbjct: 671 AVSKSSPQPQQTSPKK-----DAAP---KQDLSKAPEPKKPPPLVKQPTLHGSPSA--KA 720
Query: 1342 KRTRRAQSCDKLEPDRRRPPDPTGTSE 1368
K+ A S K P P +P+ SE
Sbjct: 721 KQPPEADSLSKPAP----PKEPSVPSE 743
Score = 40.8 bits (94), Expect = 0.009
Identities = 16/27 (59%), Positives = 17/27 (62%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSP 1106
PPPPPPPP PP P PP L +SP
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 37.4 bits (85), Expect = 0.100
Identities = 13/19 (68%), Positives = 13/19 (68%)
Query: 1080 PPPPPPPPTQESPPSPDPP 1098
PPPPPPPP PP P PP
Sbjct: 2405 PPPPPPPPPPPPPPPPPPP 2423
Score = 37.4 bits (85), Expect = 0.100
Identities = 13/19 (68%), Positives = 13/19 (68%)
Query: 1080 PPPPPPPPTQESPPSPDPP 1098
PPPPPPPP PP P PP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPP 2424
Score = 34.3 bits (77), Expect = 0.84
Identities = 15/31 (48%), Positives = 15/31 (48%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSPCWSP 1110
PPPPPPPP P SP P L SP
Sbjct: 2418 PPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Score = 33.5 bits (75), Expect = 1.4
Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 32/220 (14%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEP 1139
P P PPP + P PS P E +S P E S P
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPP----EADSLSKPA------------PPKEPSVP 741
Query: 1140 GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGP 1199
E AP +P+ + P + S K + P + +QA +K
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ--SQAEEKTT------- 792
Query: 1200 GSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPER 1259
PP S KPS S E ++ P + S + E +G ++
Sbjct: 793 ----PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ---KQ 845
Query: 1260 TLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEA 1299
P + + A PKP A P + P PG R A
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 32.3 bits (72), Expect = 3.2
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 1082 PPPPPPTQESPPSPDPPSLGNNSSPCWSPE 1111
PPPPPP PP P PP P SP+
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Score = 32.3 bits (72), Expect = 3.2
Identities = 11/21 (52%), Positives = 14/21 (66%)
Query: 1080 PPPPPPPPTQESPPSPDPPSL 1100
PPPPPPPP PP+ P++
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTI 2437
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 61.2 bits (147), Expect = 6e-09
Identities = 95/435 (21%), Positives = 148/435 (34%), Gaps = 75/435 (17%)
Query: 959 EGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFS 1018
E E T K+ + QG+P PP +P P P +Q G +G S
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGI-IKPPLQQQPPKPIP-KQQGPGRDPLQQDGTPKSIS 240
Query: 1019 RRVLEESSSYPRTLRTVRPGLSEAPLP-----PLQKKRRRGLFHFRRPRSFKGDRGPGSP 1073
+ E+ S P G ++ P PLQ+ R P++ + D G
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR-------PQTKQADIVRGES 293
Query: 1074 TTGLLLPPPPPP--PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRK 1131
L P PP PT PP+ P + P P + S L
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL----------- 342
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKR 1191
PGT + P V PG + + GP + + Q ++
Sbjct: 343 -----------AQQPGTVKPP----VQPPGTTKPPA-------QPLGPAKPPAQQTGSEK 380
Query: 1192 RSSDDAGPGSWKPPP-----PPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQD 1246
SS+ GP + PP P Q P+ ++ +A++ ++P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 1247 GEEEKEGTLFPERTLPARNAKLQ-----DPALAPWPPKPVAVPRG--RQPPQEPGVREEA 1299
++ G + ++ P + + Q P+ P P KP G + PPQ+PG A
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG---SA 497
Query: 1300 EAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRR--AQSCDKLEPDR 1357
+ PG KP Q P P PG P + + + AQ +P
Sbjct: 498 KPPSQQPGSTKP------PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 1358 R---RPPDPTGTSEP 1369
+ +P TG+ +P
Sbjct: 552 QQSTKPVSQTGSGKP 566
Score = 40.8 bits (94), Expect = 0.009
Identities = 106/447 (23%), Positives = 153/447 (34%), Gaps = 94/447 (21%)
Query: 947 LGGSQPTA--SGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENG 1004
LG ++P A +GS + SE P G K Q G + P PGP +P GT
Sbjct: 366 LGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTP-AQQPGPAKPPTQQVGT----- 417
Query: 1005 MATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGL---SEAPLPPLQKKRRRGLFHFRRP 1061
P+ L +PGL ++AP P ++ G
Sbjct: 418 ------------------------PKPLAQ-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 1062 RSFKG-----DRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSL 1116
++ G GP P + L P P PPP Q P P P G+ P P
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP------ 504
Query: 1117 LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREG 1176
G + P ++ G P + G +QQP G A P ++ ++
Sbjct: 505 ----GSTKPPP--QQPGPAKPSPQQPGSTKPPSQQP---GSAKPSAQQPSPAKPSAQQST 555
Query: 1177 PGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPN-- 1234
Q GS + Q S A K PP K E H+ E++ N
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSA-----KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 1235 HSCQ---------SPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPV---- 1281
CQ +P+P + +E +R L A + PV
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS 670
Query: 1282 AVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKP 1341
AV + PQ+ ++ DAAP K L + + + P V+ P G +A K
Sbjct: 671 AVSKSSPQPQQTSPKK-----DAAP---KQDLSKAPEPKKPPPLVKQPTLHGSPSA--KA 720
Query: 1342 KRTRRAQSCDKLEPDRRRPPDPTGTSE 1368
K+ A S K P P +P+ SE
Sbjct: 721 KQPPEADSLSKPAP----PKEPSVPSE 743
Score = 40.8 bits (94), Expect = 0.009
Identities = 16/27 (59%), Positives = 17/27 (62%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSP 1106
PPPPPPPP PP P PP L +SP
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 37.4 bits (85), Expect = 0.100
Identities = 13/19 (68%), Positives = 13/19 (68%)
Query: 1080 PPPPPPPPTQESPPSPDPP 1098
PPPPPPPP PP P PP
Sbjct: 2405 PPPPPPPPPPPPPPPPPPP 2423
Score = 37.4 bits (85), Expect = 0.100
Identities = 13/19 (68%), Positives = 13/19 (68%)
Query: 1080 PPPPPPPPTQESPPSPDPP 1098
PPPPPPPP PP P PP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPP 2424
Score = 34.3 bits (77), Expect = 0.84
Identities = 15/31 (48%), Positives = 15/31 (48%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSPCWSP 1110
PPPPPPPP P SP P L SP
Sbjct: 2418 PPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Score = 33.5 bits (75), Expect = 1.4
Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 32/220 (14%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEP 1139
P P PPP + P PS P E +S P E S P
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPP----EADSLSKPA------------PPKEPSVP 741
Query: 1140 GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGP 1199
E AP +P+ + P + S K + P + +QA +K
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ--SQAEEKTT------- 792
Query: 1200 GSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPER 1259
PP S KPS S E ++ P + S + E +G ++
Sbjct: 793 ----PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ---KQ 845
Query: 1260 TLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEA 1299
P + + A PKP A P + P PG R A
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 32.3 bits (72), Expect = 3.2
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 1082 PPPPPPTQESPPSPDPPSLGNNSSPCWSPE 1111
PPPPPP PP P PP P SP+
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Score = 32.3 bits (72), Expect = 3.2
Identities = 11/21 (52%), Positives = 14/21 (66%)
Query: 1080 PPPPPPPPTQESPPSPDPPSL 1100
PPPPPPPP PP+ P++
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTI 2437
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 60.1 bits (144), Expect = 1e-08
Identities = 77/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1026 SSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGL-------- 1077
SS PRT P +SE P+P L + R P S + P T L
Sbjct: 1082 SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1141
Query: 1078 ---LLPPPPPP--PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSF-RRK 1131
PPPP P PPT+ +PP PP G SP G G P RR+
Sbjct: 1142 LEPKRPPPPRPVAPPTRPAPPQRPPPPSGAR-----SPAPTRKEFGGIGAPPSPGVARRE 1196
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKR 1191
M E +PGT ++ + G + P + GPGP
Sbjct: 1197 M--------EAPKSPGTTRKDNI-GRSQPSPQAGLA--------GPGP------------ 1227
Query: 1192 RSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEK 1251
AG + +P PP++ S + + ES S S +
Sbjct: 1228 -----AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP 1282
Query: 1252 EGTLFPERTLPARNAKLQDPALAPWPPKPVAVPR-GRQPPQEPGVREEAEAGDAAPGVNK 1310
+ P+ +LP +LQ+P + P P + P+ + P +P R + + ++
Sbjct: 1283 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQ 1342
Query: 1311 PRLRLSSQQDQEEPEVQGPPDPGRRTAPLK 1340
P+++ + D G+R +PLK
Sbjct: 1343 PQVKTNGISD------------GKRESPLK 1360
Score = 32.0 bits (71), Expect = 4.2
Identities = 54/219 (24%), Positives = 75/219 (34%), Gaps = 46/219 (21%)
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP 1037
RP PP+ PP G S PAP ++ G+ G+ +RR +E S P T R
Sbjct: 1158 RPAPPQRPPPPSGARS-PAPTRKEFGGIGAPPSPGV----ARREMEAPKS-PGTTRKDNI 1211
Query: 1038 GLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDP 1097
G S+ P G GPG P PP +P S
Sbjct: 1212 GRSQ-------------------PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR 1252
Query: 1098 PSLGNNSSPCWSPEEESSLLPGFGGGRGPSF-RRKMGTEGSEPGEGG-PAPGTAQQPRVH 1155
S G + S E+S +G +F + + + P + P P Q +
Sbjct: 1253 ASAGRLTPESQSKTSETS--------KGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLV 1304
Query: 1156 GVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSS 1194
VA P + GP P+ E Q + RSS
Sbjct: 1305 PVAAP-----------MPQSGPQPNLETPPQPPPRSRSS 1332
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/254 (29%), Positives = 88/254 (34%), Gaps = 44/254 (17%)
Query: 983 RTTPPGPGRPSMPAPGTRQE---NGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP-- 1037
R +PP PG P P+PG T L G S R SSS P + R P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG-----SIRQSPLSSSSPFSNRPPLPPT 255
Query: 1038 ---GLSEAPLPPLQKKRRRGLFHFRR-PRSFKGDRGPGSPTT----GLLLPPPPPPPPTQ 1089
L + P PP R H P + P P+T PPPPPPP++
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 1090 ESPPSPDPPSLGNNSSPCWSPEEESSL--------LPGFGGG-RGPSFRRKMGTEGSEPG 1140
PP P S GN+ +P P+ SL PG G P R PG
Sbjct: 316 PGPPPLPPSSSGNDETP-RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
Query: 1141 EGGPAPGTAQQPRVHGV--ALPGLERAKGWS-FDGKREGPGPDQEGSTQAWQKRRSSDDA 1197
GP P R ALP + S D R GP P
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR------------ 422
Query: 1198 GPGSWKPPPPPQST 1211
P + PPPPP ST
Sbjct: 423 -PSAGAPPPPPPST 435
Score = 59.7 bits (143), Expect = 2e-08
Identities = 80/314 (25%), Positives = 102/314 (32%), Gaps = 54/314 (17%)
Query: 1062 RSFKGDRGPGS---PTTGLLLPPP-------PPPPPTQESPPSPDPPSLGNNSSPCWSPE 1111
+ F GPG P+ G PP PPP P S P PP + + P S
Sbjct: 139 KPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 1112 EESSLLPGFGGGR----GPSFRRKMGTEGSEPGEGG--PAPGTAQQPRVHGVALPGLERA 1165
P GG R GP+ G G+ G G +P ++ P + P L
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN---RPPLPPT 255
Query: 1166 KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATW 1225
+ D K P P ++ PPPPPQ+ KP + R A+
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREA-----------VPPPPPQNNKPPVPSTPRPSASS 304
Query: 1226 HIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTL-----------PARNAKLQDPALA 1274
A P S P P E P+R L P R+ L P +
Sbjct: 305 Q-APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP-S 362
Query: 1275 PWPPKPVAVPRGRQP--PQEPGVREEAEAGDAAP---------GVNKPRLRLSSQQDQEE 1323
PP PV P GR P P V A P GV+ PR +
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 1324 PEVQGPPDPGRRTA 1337
P PP P T+
Sbjct: 423 PSAGAPPPPPPSTS 436
Score = 57.4 bits (137), Expect = 9e-08
Identities = 95/389 (24%), Positives = 129/389 (33%), Gaps = 52/389 (13%)
Query: 948 GGSQPTASGSWE-GLSELPTHGYKLRHQTQGRPRPP------RTT-------PPGPGRPS 993
GG P G ++ G+ +L + R G RPP R+T P GPGR
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTAN--RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP 151
Query: 994 MPAPGTRQ--ENGMATRLDEGLEDFFSR--RVLEESSSYPRTLRTVRPGLSEAPLPPLQK 1049
+P+PG R R+ D S+ + S PR +++ P+P +
Sbjct: 152 VPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 1050 KRRRGLFHFRRPRSFKGDRG-----------PGSPTTGLLLPPPPPPPPTQ--ESPPSPD 1096
+ G P F G+RG P S ++ PP PP P++ + P P
Sbjct: 212 QPSPG----PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
Query: 1097 PPSLGNNSS---PCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAP------G 1147
PP +GN S P + P PS + P GP P G
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 1148 TAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPP 1207
+ PR+ L G R GP P R +GP PPPP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPSERPPPPVRDPPGRSGP---LPPPP 383
Query: 1208 PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAK 1267
P S S S R AT + S + P P P + RN
Sbjct: 384 PVSRNGSTS--RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 1268 LQDPALAPWPPKPVAVPRGRQPPQEPGVR 1296
P W + P PP EP V+
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYVQ 470
Score = 41.2 bits (95), Expect = 0.007
Identities = 74/304 (24%), Positives = 99/304 (32%), Gaps = 51/304 (16%)
Query: 1079 LPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEE---SSLLPGFGGGRGPSFRRKMGTE 1135
+PPPP PPP P +L N P + E+ ++LL +G ++ + +
Sbjct: 3 VPPPPAPPP-------PPTFALANTEKPTLNKTEQAGRNALLSDI--SKGKKLKKTVTND 53
Query: 1136 GSEP--------GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQA 1187
S P G GG G G G G SF G G P G QA
Sbjct: 54 RSAPILDKPKGAGAGGGGGGFGGGGGFGG----GGGGGGGGSFGG---GGPPGLGGLFQA 106
Query: 1188 WQKRRSS----DDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPA 1243
+ S D+ GS P PP R+ + + S P PSP
Sbjct: 107 GMPKLRSTANRDNDSGGSRPPLLPPGG---------RSTSAKPFSPPSGPGR-FPVPSPG 156
Query: 1244 SQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPV-AVPRGRQPPQEPGVREEAEAG 1302
+ G E + P + P P P+P+ + P R P PG + G
Sbjct: 157 HRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 1303 DAAPGVNKPR-LRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPP 1361
P R L ++ P P R P P R DK P PP
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD----DKPPP----PP 268
Query: 1362 DPTG 1365
P G
Sbjct: 269 PPVG 272
Score = 40.8 bits (94), Expect = 0.009
Identities = 72/334 (21%), Positives = 106/334 (31%), Gaps = 64/334 (19%)
Query: 1080 PPPPPPPPTQESPPSPDPPSL-----------------GNNSSPCWSPEEESSLL---PG 1119
PPP PPPP + + + P+L G + + + +L G
Sbjct: 5 PPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKG 64
Query: 1120 FG-GGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWS-----FDGK 1173
G GG G F G G G GG + G P + G+ G+ + + + G
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGS 124
Query: 1174 REGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAP 1233
R P ST A + S +GPG + P P + P P
Sbjct: 125 RPPLLPPGGRSTSA---KPFSPPSGPGRFPVPSPGHRSGP-----------------PEP 164
Query: 1234 NHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEP 1293
+ P + + P P +++ + P P P G PP P
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 1294 GVREEAEAG---------DAAPGVNKPRL------RLSSQQDQEEPEVQGPPDPGRRTAP 1338
G R A G ++P N+P L L + P V P R P
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 1339 LKPKRTRR--AQSCDKLEPDRRRPPDPTGTSEPG 1370
P + + S + + PP P S PG
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Score = 40.0 bits (92), Expect = 0.015
Identities = 80/350 (22%), Positives = 114/350 (32%), Gaps = 81/350 (23%)
Query: 1082 PPPPPPTQESPPSPDPPSLGNNSSPCWSPEEES---SLLPGFGGGRGPSFRRKMGTEGSE 1138
P PPPP +PP P +L N P + E++ +LL +G ++ + + S
Sbjct: 2 PVPPPP---APPPPPTFALANTEKPTLNKTEQAGRNALLSDIS--KGKKLKKTVTNDRSA 56
Query: 1139 P--------GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQK 1190
P G GG G G G G SF G G P G QA
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGG----GGGGGGGGSFGG---GGPPGLGGLFQAGMP 109
Query: 1191 RRSS----DDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQD 1246
+ S D+ GS P PP R+ + + S P PSP +
Sbjct: 110 KLRSTANRDNDSGGSRPPLLPPGG---------RSTSAKPFSPPSGPGRF-PVPSPGHRS 159
Query: 1247 GEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVA----------VPRGRQ-------P 1289
G E + P + P P P+P+ VP G + P
Sbjct: 160 GPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP 219
Query: 1290 PQEPGVREEAEAG---------DAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTA--- 1337
P PG R A G ++P N+P L + + ++ PP G R +
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Query: 1338 ---------------PLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
P P+ + +Q+ P R P P S G D
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Score = 38.9 bits (89), Expect = 0.034
Identities = 44/142 (30%), Positives = 50/142 (35%), Gaps = 9/142 (6%)
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRT-LRTVR 1036
RP PP PPG P +P P NG +R SR ++ S PR L R
Sbjct: 364 RPPPPVRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPD 1096
P P PP R G F R P + L PPP P T +S PS
Sbjct: 423 PSAGAPPPPPPSTSIRNG-FQDSPCEDEWESRFYFHPISDL--PPPEPYVQTTKSYPS-- 477
Query: 1097 PPSLGNNSSPCWSPEEESSLLP 1118
L N S S E P
Sbjct: 478 --KLARNESRSGSNRRERGAPP 497
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/254 (29%), Positives = 88/254 (34%), Gaps = 44/254 (17%)
Query: 983 RTTPPGPGRPSMPAPGTRQE---NGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP-- 1037
R +PP PG P P+PG T L G S R SSS P + R P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG-----SIRQSPLSSSSPFSNRPPLPPT 255
Query: 1038 ---GLSEAPLPPLQKKRRRGLFHFRR-PRSFKGDRGPGSPTT----GLLLPPPPPPPPTQ 1089
L + P PP R H P + P P+T PPPPPPP++
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 1090 ESPPSPDPPSLGNNSSPCWSPEEESSL--------LPGFGGG-RGPSFRRKMGTEGSEPG 1140
PP P S GN+ +P P+ SL PG G P R PG
Sbjct: 316 PGPPPLPPSSSGNDETP-RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
Query: 1141 EGGPAPGTAQQPRVHGV--ALPGLERAKGWS-FDGKREGPGPDQEGSTQAWQKRRSSDDA 1197
GP P R ALP + S D R GP P
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR------------ 422
Query: 1198 GPGSWKPPPPPQST 1211
P + PPPPP ST
Sbjct: 423 -PSAGAPPPPPPST 435
Score = 59.7 bits (143), Expect = 2e-08
Identities = 80/314 (25%), Positives = 102/314 (32%), Gaps = 54/314 (17%)
Query: 1062 RSFKGDRGPGS---PTTGLLLPPP-------PPPPPTQESPPSPDPPSLGNNSSPCWSPE 1111
+ F GPG P+ G PP PPP P S P PP + + P S
Sbjct: 139 KPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 1112 EESSLLPGFGGGR----GPSFRRKMGTEGSEPGEGG--PAPGTAQQPRVHGVALPGLERA 1165
P GG R GP+ G G+ G G +P ++ P + P L
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN---RPPLPPT 255
Query: 1166 KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATW 1225
+ D K P P ++ PPPPPQ+ KP + R A+
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREA-----------VPPPPPQNNKPPVPSTPRPSASS 304
Query: 1226 HIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTL-----------PARNAKLQDPALA 1274
A P S P P E P+R L P R+ L P +
Sbjct: 305 Q-APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP-S 362
Query: 1275 PWPPKPVAVPRGRQP--PQEPGVREEAEAGDAAP---------GVNKPRLRLSSQQDQEE 1323
PP PV P GR P P V A P GV+ PR +
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 1324 PEVQGPPDPGRRTA 1337
P PP P T+
Sbjct: 423 PSAGAPPPPPPSTS 436
Score = 57.4 bits (137), Expect = 9e-08
Identities = 95/389 (24%), Positives = 129/389 (33%), Gaps = 52/389 (13%)
Query: 948 GGSQPTASGSWE-GLSELPTHGYKLRHQTQGRPRPP------RTT-------PPGPGRPS 993
GG P G ++ G+ +L + R G RPP R+T P GPGR
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTAN--RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP 151
Query: 994 MPAPGTRQ--ENGMATRLDEGLEDFFSR--RVLEESSSYPRTLRTVRPGLSEAPLPPLQK 1049
+P+PG R R+ D S+ + S PR +++ P+P +
Sbjct: 152 VPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 1050 KRRRGLFHFRRPRSFKGDRG-----------PGSPTTGLLLPPPPPPPPTQ--ESPPSPD 1096
+ G P F G+RG P S ++ PP PP P++ + P P
Sbjct: 212 QPSPG----PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
Query: 1097 PPSLGNNSS---PCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAP------G 1147
PP +GN S P + P PS + P GP P G
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 1148 TAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPP 1207
+ PR+ L G R GP P R +GP PPPP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPSERPPPPVRDPPGRSGP---LPPPP 383
Query: 1208 PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAK 1267
P S S S R AT + S + P P P + RN
Sbjct: 384 PVSRNGSTS--RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 1268 LQDPALAPWPPKPVAVPRGRQPPQEPGVR 1296
P W + P PP EP V+
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYVQ 470
Score = 41.2 bits (95), Expect = 0.007
Identities = 74/304 (24%), Positives = 99/304 (32%), Gaps = 51/304 (16%)
Query: 1079 LPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEE---SSLLPGFGGGRGPSFRRKMGTE 1135
+PPPP PPP P +L N P + E+ ++LL +G ++ + +
Sbjct: 3 VPPPPAPPP-------PPTFALANTEKPTLNKTEQAGRNALLSDI--SKGKKLKKTVTND 53
Query: 1136 GSEP--------GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQA 1187
S P G GG G G G G SF G G P G QA
Sbjct: 54 RSAPILDKPKGAGAGGGGGGFGGGGGFGG----GGGGGGGGSFGG---GGPPGLGGLFQA 106
Query: 1188 WQKRRSS----DDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPA 1243
+ S D+ GS P PP R+ + + S P PSP
Sbjct: 107 GMPKLRSTANRDNDSGGSRPPLLPPGG---------RSTSAKPFSPPSGPGR-FPVPSPG 156
Query: 1244 SQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPV-AVPRGRQPPQEPGVREEAEAG 1302
+ G E + P + P P P+P+ + P R P PG + G
Sbjct: 157 HRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 1303 DAAPGVNKPR-LRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPP 1361
P R L ++ P P R P P R DK P PP
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD----DKPPP----PP 268
Query: 1362 DPTG 1365
P G
Sbjct: 269 PPVG 272
Score = 40.8 bits (94), Expect = 0.009
Identities = 72/334 (21%), Positives = 106/334 (31%), Gaps = 64/334 (19%)
Query: 1080 PPPPPPPPTQESPPSPDPPSL-----------------GNNSSPCWSPEEESSLL---PG 1119
PPP PPPP + + + P+L G + + + +L G
Sbjct: 5 PPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKG 64
Query: 1120 FG-GGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWS-----FDGK 1173
G GG G F G G G GG + G P + G+ G+ + + + G
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGS 124
Query: 1174 REGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAP 1233
R P ST A + S +GPG + P P + P P
Sbjct: 125 RPPLLPPGGRSTSA---KPFSPPSGPGRFPVPSPGHRSGP-----------------PEP 164
Query: 1234 NHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEP 1293
+ P + + P P +++ + P P P G PP P
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 1294 GVREEAEAG---------DAAPGVNKPRL------RLSSQQDQEEPEVQGPPDPGRRTAP 1338
G R A G ++P N+P L L + P V P R P
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 1339 LKPKRTRR--AQSCDKLEPDRRRPPDPTGTSEPG 1370
P + + S + + PP P S PG
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Score = 40.0 bits (92), Expect = 0.015
Identities = 80/350 (22%), Positives = 114/350 (32%), Gaps = 81/350 (23%)
Query: 1082 PPPPPPTQESPPSPDPPSLGNNSSPCWSPEEES---SLLPGFGGGRGPSFRRKMGTEGSE 1138
P PPPP +PP P +L N P + E++ +LL +G ++ + + S
Sbjct: 2 PVPPPP---APPPPPTFALANTEKPTLNKTEQAGRNALLSDIS--KGKKLKKTVTNDRSA 56
Query: 1139 P--------GEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQK 1190
P G GG G G G G SF G G P G QA
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGG----GGGGGGGGSFGG---GGPPGLGGLFQAGMP 109
Query: 1191 RRSS----DDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQD 1246
+ S D+ GS P PP R+ + + S P PSP +
Sbjct: 110 KLRSTANRDNDSGGSRPPLLPPGG---------RSTSAKPFSPPSGPGRF-PVPSPGHRS 159
Query: 1247 GEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVA----------VPRGRQ-------P 1289
G E + P + P P P+P+ VP G + P
Sbjct: 160 GPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP 219
Query: 1290 PQEPGVREEAEAG---------DAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTA--- 1337
P PG R A G ++P N+P L + + ++ PP G R +
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Query: 1338 ---------------PLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
P P+ + +Q+ P R P P S G D
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Score = 38.9 bits (89), Expect = 0.034
Identities = 44/142 (30%), Positives = 50/142 (35%), Gaps = 9/142 (6%)
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRT-LRTVR 1036
RP PP PPG P +P P NG +R SR ++ S PR L R
Sbjct: 364 RPPPPVRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPD 1096
P P PP R G F R P + L PPP P T +S PS
Sbjct: 423 PSAGAPPPPPPSTSIRNG-FQDSPCEDEWESRFYFHPISDL--PPPEPYVQTTKSYPS-- 477
Query: 1097 PPSLGNNSSPCWSPEEESSLLP 1118
L N S S E P
Sbjct: 478 --KLARNESRSGSNRRERGAPP 497
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 59.3 bits (142), Expect = 2e-08
Identities = 78/315 (24%), Positives = 110/315 (34%), Gaps = 64/315 (20%)
Query: 1026 SSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGL-------- 1077
SS PRT P +SE P+P L + R P S + P T L
Sbjct: 1082 SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1141
Query: 1078 ---LLPPPPPP--PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSF-RRK 1131
PPPP P PPT+ +PP PP G SP G G P RR+
Sbjct: 1142 LEPKRPPPPRPVAPPTRPAPPQRPPPPSGAR-----SPAPTRKEFGGIGAPPSPGVARRE 1196
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKR 1191
M E +PGT ++ + G + P + GPGP
Sbjct: 1197 M--------EAPKSPGTTRKDNI-GRSQPSPQAGLA--------GPGP------------ 1227
Query: 1192 RSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEK 1251
AG + +P PP++ S + + ES S S +
Sbjct: 1228 -----AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP 1282
Query: 1252 EGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG--RQPPQEPGVREEAEAGDAAPGVN 1309
+ P+ +LP +LQ+P + P P + P+ PPQ P + + + P
Sbjct: 1283 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPP---PRSRSSHSLPS-- 1337
Query: 1310 KPRLRLSSQQDQEEP 1324
SSQ QE+P
Sbjct: 1338 ----EASSQPQQEQP 1348
Score = 32.3 bits (72), Expect = 3.2
Identities = 58/239 (24%), Positives = 81/239 (33%), Gaps = 49/239 (20%)
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP 1037
RP PP+ PP G S PAP ++ G+ G+ +RR +E S P T R
Sbjct: 1158 RPAPPQRPPPPSGARS-PAPTRKEFGGIGAPPSPGV----ARREMEAPKS-PGTTRKDNI 1211
Query: 1038 GLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDP 1097
G S+ P G GPG P PP +P S
Sbjct: 1212 GRSQ-------------------PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR 1252
Query: 1098 PSLGNNSSPCWSPEEESSLLPGFGGGRGPSF-RRKMGTEGSEPGEGG-PAPGTAQQPRVH 1155
S G + S E+S +G +F + + + P + P P Q +
Sbjct: 1253 ASAGRLTPESQSKTSETS--------KGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLV 1304
Query: 1156 GVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPS 1214
VA P + GP P+ E Q + RSS + PQ +PS
Sbjct: 1305 PVAAP-----------MPQSGPQPNLETPPQPPPRSRSSHSLPS---EASSQPQQEQPS 1349
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 59.3 bits (142), Expect = 2e-08
Identities = 117/483 (24%), Positives = 154/483 (31%), Gaps = 85/483 (17%)
Query: 924 SGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPR 983
S P+D++ N P +S GS S S GLS+ P Y P+PP
Sbjct: 118 SSDPRDIDQD--NRSTSPSIYSP--GSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPD 173
Query: 984 TTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAP 1043
+TP P P P A + R+ + P + PG +
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPP------TSRMFQAPPGAPPPHPQLYPGGTGGV 227
Query: 1044 L--PPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQES-----PPS-- 1094
L PP+ P+ G P G PPP P S PP+
Sbjct: 228 LSGPPMG------------PKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 1095 PDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGG-PAPGTAQQPR 1153
P P G N P + P P+ R S PG G P PG P
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNL--PPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
Query: 1154 VHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKP 1213
G + GL PGP ++G T A S P S P PP
Sbjct: 334 AMGQGMGGLP-------------PGP-EKGPTLA----PSPHSLPPASSSAPAPPMRFPY 375
Query: 1214 SFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERT------LPARNAK 1267
S S+ A A + S+ + S SP PASQ FP T P + +
Sbjct: 376 SSSSSSSAAA----SSSSSSSSSSASPFPASQALPSYPHS--FPPPTSLSVSNQPPKYTQ 429
Query: 1268 LQDPALAPW---PPKP------VAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQ 1318
P+ A W PP P +A P P ++ A + + Q
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 1319 QDQEEPEVQ---------GPPDPGRRTAPLKPKRTRRAQ---SCDKLEPDRRRPPDPTGT 1366
Q Q++ + Q GPP PG PL+ + A L R PP P
Sbjct: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 1367 SEP 1369
P
Sbjct: 550 PPP 552
Score = 41.2 bits (95), Expect = 0.007
Identities = 93/414 (22%), Positives = 131/414 (31%), Gaps = 75/414 (18%)
Query: 948 GGSQPTASGSWEGLSELPTHGYKLRHQTQGR----PRPPRTTPPGPGR-PSMPAPGTRQE 1002
GG ++ G G + P + + G P P TTP G G PS P P
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--- 293
Query: 1003 NGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPR 1062
+ L + R L +S+ P PGL PLP H P
Sbjct: 294 ---FPHVTPNLPPPPALRPLNNASASP-------PGLGAQPLPG----------HLPSPH 333
Query: 1063 SFKGDRG---PGSPTTGLLLPPPPPPPPTQESPPSPD---PPSLGNNSSPCWSPEEESSL 1116
+ G PG L P P PP S P+P P S ++SS S SS
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS- 392
Query: 1117 LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREG 1176
F S P P + + P L WS +G
Sbjct: 393 -----SSSASPFPASQALP-SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS-----QG 441
Query: 1177 PGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST-KPSFSA--------MRRAEATWHI 1227
P P + + ++ +A PG + P QST P S ++ +
Sbjct: 442 PPP-----PPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ 496
Query: 1228 AEESAPNHSCQSPSPASQDGEEEKEGT---LFPERTLPARNAKLQDPALAPWPPKPVAVP 1284
++ +H P P + G+ P P+ +L P+PP P +P
Sbjct: 497 QQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG------SLRPYPPGPAHLP 550
Query: 1285 RGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAP 1338
PP ++AG P V+ SS P P G + AP
Sbjct: 551 ----PPHSQ--VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP 598
Score = 37.7 bits (86), Expect = 0.076
Identities = 49/201 (24%), Positives = 62/201 (30%), Gaps = 30/201 (14%)
Query: 927 PQDMESQLGNLG-IPPG-----------WFSGLGGSQPTASGSWEGLSELPTHGYKLRHQ 974
P M LG+L PPG +S G + P S S S Y H
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPG-TRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLR 1033
+ P P G P P P T ++T + + P R
Sbjct: 589 S------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 1034 TVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDR--------GPGSPTTGLLLPPPPPP 1085
PG + PP K F P ++G PGSPT G P P PP
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVG---PGPLPP 699
Query: 1086 PPTQESPPSPDPPSLGNNSSP 1106
P P PP+ + P
Sbjct: 700 AGPSGLPSLPPPPAAPASGPP 720
Score = 37.0 bits (84), Expect = 0.13
Identities = 69/249 (27%), Positives = 88/249 (35%), Gaps = 60/249 (24%)
Query: 1072 SPTTGLLLPPPP-----PPPPTQ----ESPPSPDPPSLGNNSSPCWS----PEEESSLLP 1118
SP+ G L P PP PPP +Q ++ P+ P S +NSS S P S
Sbjct: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592
Query: 1119 GFGGGRGP------------SFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAK 1166
G G P + + T S P G + P +G P K
Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPA--GYKTASPPGPPPYGKRAPSPGAYK 650
Query: 1167 GWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP----------PPPPQSTKPSFS 1216
+ G + G P T R +S AGPG++KP PP S PS
Sbjct: 651 TATPPGYKPGSPPSFRTGTPPGY-RGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709
Query: 1217 AMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPW 1276
A A S P P A+Q +E E PE +P PA +P
Sbjct: 710 PPPAAPA-------SGP------PLSATQIKQEPAEEYETPESPVP--------PARSPS 748
Query: 1277 -PPKPVAVP 1284
PPK V VP
Sbjct: 749 PPPKVVDVP 757
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 59.3 bits (142), Expect = 2e-08
Identities = 117/483 (24%), Positives = 154/483 (31%), Gaps = 85/483 (17%)
Query: 924 SGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPR 983
S P+D++ N P +S GS S S GLS+ P Y P+PP
Sbjct: 118 SSDPRDIDQD--NRSTSPSIYSP--GSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPD 173
Query: 984 TTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAP 1043
+TP P P P A + R+ + P + PG +
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPP------TSRMFQAPPGAPPPHPQLYPGGTGGV 227
Query: 1044 L--PPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQES-----PPS-- 1094
L PP+ P+ G P G PPP P S PP+
Sbjct: 228 LSGPPMG------------PKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 1095 PDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGG-PAPGTAQQPR 1153
P P G N P + P P+ R S PG G P PG P
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNL--PPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
Query: 1154 VHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKP 1213
G + GL PGP ++G T A S P S P PP
Sbjct: 334 AMGQGMGGLP-------------PGP-EKGPTLA----PSPHSLPPASSSAPAPPMRFPY 375
Query: 1214 SFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERT------LPARNAK 1267
S S+ A A + S+ + S SP PASQ FP T P + +
Sbjct: 376 SSSSSSSAAA----SSSSSSSSSSASPFPASQALPSYPHS--FPPPTSLSVSNQPPKYTQ 429
Query: 1268 LQDPALAPW---PPKP------VAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQ 1318
P+ A W PP P +A P P ++ A + + Q
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 1319 QDQEEPEVQ---------GPPDPGRRTAPLKPKRTRRAQ---SCDKLEPDRRRPPDPTGT 1366
Q Q++ + Q GPP PG PL+ + A L R PP P
Sbjct: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 1367 SEP 1369
P
Sbjct: 550 PPP 552
Score = 41.2 bits (95), Expect = 0.007
Identities = 93/414 (22%), Positives = 131/414 (31%), Gaps = 75/414 (18%)
Query: 948 GGSQPTASGSWEGLSELPTHGYKLRHQTQGR----PRPPRTTPPGPGR-PSMPAPGTRQE 1002
GG ++ G G + P + + G P P TTP G G PS P P
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--- 293
Query: 1003 NGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPR 1062
+ L + R L +S+ P PGL PLP H P
Sbjct: 294 ---FPHVTPNLPPPPALRPLNNASASP-------PGLGAQPLPG----------HLPSPH 333
Query: 1063 SFKGDRG---PGSPTTGLLLPPPPPPPPTQESPPSPD---PPSLGNNSSPCWSPEEESSL 1116
+ G PG L P P PP S P+P P S ++SS S SS
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS- 392
Query: 1117 LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREG 1176
F S P P + + P L WS +G
Sbjct: 393 -----SSSASPFPASQALP-SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS-----QG 441
Query: 1177 PGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST-KPSFSA--------MRRAEATWHI 1227
P P + + ++ +A PG + P QST P S ++ +
Sbjct: 442 PPP-----PPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ 496
Query: 1228 AEESAPNHSCQSPSPASQDGEEEKEGT---LFPERTLPARNAKLQDPALAPWPPKPVAVP 1284
++ +H P P + G+ P P+ +L P+PP P +P
Sbjct: 497 QQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG------SLRPYPPGPAHLP 550
Query: 1285 RGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAP 1338
PP ++AG P V+ SS P P G + AP
Sbjct: 551 ----PPHSQ--VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP 598
Score = 37.7 bits (86), Expect = 0.076
Identities = 49/201 (24%), Positives = 62/201 (30%), Gaps = 30/201 (14%)
Query: 927 PQDMESQLGNLG-IPPG-----------WFSGLGGSQPTASGSWEGLSELPTHGYKLRHQ 974
P M LG+L PPG +S G + P S S S Y H
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPG-TRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLR 1033
+ P P G P P P T ++T + + P R
Sbjct: 589 S------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 1034 TVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDR--------GPGSPTTGLLLPPPPPP 1085
PG + PP K F P ++G PGSPT G P P PP
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVG---PGPLPP 699
Query: 1086 PPTQESPPSPDPPSLGNNSSP 1106
P P PP+ + P
Sbjct: 700 AGPSGLPSLPPPPAAPASGPP 720
Score = 37.0 bits (84), Expect = 0.13
Identities = 69/249 (27%), Positives = 88/249 (35%), Gaps = 60/249 (24%)
Query: 1072 SPTTGLLLPPPP-----PPPPTQ----ESPPSPDPPSLGNNSSPCWS----PEEESSLLP 1118
SP+ G L P PP PPP +Q ++ P+ P S +NSS S P S
Sbjct: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592
Query: 1119 GFGGGRGP------------SFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAK 1166
G G P + + T S P G + P +G P K
Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPA--GYKTASPPGPPPYGKRAPSPGAYK 650
Query: 1167 GWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP----------PPPPQSTKPSFS 1216
+ G + G P T R +S AGPG++KP PP S PS
Sbjct: 651 TATPPGYKPGSPPSFRTGTPPGY-RGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709
Query: 1217 AMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPW 1276
A A S P P A+Q +E E PE +P PA +P
Sbjct: 710 PPPAAPA-------SGP------PLSATQIKQEPAEEYETPESPVP--------PARSPS 748
Query: 1277 -PPKPVAVP 1284
PPK V VP
Sbjct: 749 PPPKVVDVP 757
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 58.5 bits (140), Expect = 4e-08
Identities = 88/327 (26%), Positives = 107/327 (32%), Gaps = 70/327 (21%)
Query: 976 QGRPRPPRTTPPGPGRP-SMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRT 1034
QG +P RT PP PG+P P G Q G
Sbjct: 42 QGGNQPQRTPPP-PGKPEGRPPQGGNQSQGPPP--------------------------- 73
Query: 1035 VRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPS 1094
RPG E P PP + +G PR K + P P G PPP P E P
Sbjct: 74 -RPGKPEGP-PPQGGNQSQG----PPPRPGKPEGQP--PQGGNQSQGPPPRPGKPEGP-- 123
Query: 1095 PDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGG-------PAPG 1147
PP GN S + P GG + + G P +GG P PG
Sbjct: 124 --PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPG 181
Query: 1148 TAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGP--GSWKPP 1205
+ P G G + GK EGP P +Q R + P G KP
Sbjct: 182 KPEGPPPQG----GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQ 237
Query: 1206 -PPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPAR 1264
PPP KP + N + P P G G P++ LP
Sbjct: 238 GPPPHPGKPQGPPPQEG------------NKPQRPPPPGRPQGPPPPGGN--PQQPLPPP 283
Query: 1265 NAKLQDPALAPWPPKPVAVPRGRQPPQ 1291
K Q P P +P P+G QPPQ
Sbjct: 284 AGKPQGPPPPPQGGRPHRPPQG-QPPQ 309
Score = 55.1 bits (131), Expect = 5e-07
Identities = 77/300 (25%), Positives = 95/300 (31%), Gaps = 64/300 (21%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSS--PCWSPEEESSLLPGFGGGRGPSFRRKMGTEGS 1137
P PPPP + P PP GN S P + E G +GP R EG
Sbjct: 47 PQRTPPPPGK---PEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP-PRPGKPEGQ 102
Query: 1138 EPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDA 1197
P G + G +P GK EGP P +Q R +
Sbjct: 103 PPQGGNQSQGPPPRP-------------------GKPEGPPPQGGNQSQGPPPRPGKPEG 143
Query: 1198 GP---GSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
P G+ PPP+ KP E P QS P G+
Sbjct: 144 PPPQGGNQSQGPPPRPGKP---------------EGPPPQGGNQSQGPPPHPGK------ 182
Query: 1255 LFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQ---PPQEPGVREEAEAGDAAPGVNKP 1311
PE P + Q P P P+ G Q PP PG E G + G NKP
Sbjct: 183 --PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE----GPPSQGGNKP 236
Query: 1312 RL------RLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTG 1365
+ + QE + Q PP PGR P P + + PP P G
Sbjct: 237 QGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQG 296
Score = 35.4 bits (80), Expect = 0.38
Identities = 58/226 (25%), Positives = 75/226 (33%), Gaps = 21/226 (9%)
Query: 925 GSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRT 984
G P+ Q GN P G P G+ + P G QG + +
Sbjct: 97 GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGN-QSQGPPPRPGKPEGPPPQGGNQS-QG 154
Query: 985 TPPGPGRPSMPAP-GTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAP 1043
PP PG+P P P G Q G G + + +S P RPG E P
Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPH--PGKPEGPPPQGGNQSQGPPP-----RPGKPEGP 207
Query: 1044 LPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPP-----PPPTQESPPSPDPP 1098
PP + +G PR K + P PPP P PPP + + P PP
Sbjct: 208 -PPQGGNQSQG----PPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPP 262
Query: 1099 SLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGP 1144
P + L P G +GP G P +G P
Sbjct: 263 PGRPQGPPPPGGNPQQPLPPPAGKPQGPP-PPPQGGRPHRPPQGQP 307
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 57.8 bits (138), Expect = 7e-08
Identities = 120/447 (26%), Positives = 151/447 (33%), Gaps = 124/447 (27%)
Query: 976 QGRPRPPRTTPP-------GP-GRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSS 1027
QGRP P P GP G P +P +QE GL+ E+ +
Sbjct: 619 QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQE---------GLKG-------EQGAP 662
Query: 1028 YPRTLRTVRPGLSEAPLPP-----LQKKRRRGLFHFRRPRSFKGDRG-PGSP-TTGLLLP 1080
PR G AP PP + + R G + R KGD G PG P GL P
Sbjct: 663 GPR-------GHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715
Query: 1081 PPPP----PP--------------PTQESPPSP-DPPSLGNNSSPCWSPEEESSLLPGFG 1121
P PP PP P + PP P PP + P P + PG
Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE--PGER 773
Query: 1122 GGRG----PSFRRKMGTEG--SEPGEGGPA--PGTAQQPRVHG----------VALPGLE 1163
G G P R ++G +G PGE G A PG P V G + LPGL+
Sbjct: 774 GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833
Query: 1164 RAKGWSFDGKREGPGPDQEGSTQAWQKR-RSSDDAGPGSWK-----PPPPPQSTKPSFSA 1217
+G + GP P G+T + R + GP K P P +P
Sbjct: 834 GDRGEKGEAGPAGP-PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG--- 889
Query: 1218 MRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAP-- 1275
E P P Q+G G A N AP
Sbjct: 890 ------------ELGPQGPTGPPGAKGQEGAHGAPGA--------AGNPGAPGHVGAPGP 929
Query: 1276 -WPPKPVAVPRGRQPPQEPGVREE--AEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPP-- 1330
PP V P R P + G R E A + +PG PR D P + GPP
Sbjct: 930 SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR------GDPGAPGLPGPPGK 983
Query: 1331 ----DPGRRTAPLKPKRTRRAQSCDKL 1353
+PG R +P P +C K+
Sbjct: 984 GKDGEPGLRGSPGLPGPLGTKAACGKV 1010
Score = 50.4 bits (119), Expect = 1e-05
Identities = 111/445 (24%), Positives = 138/445 (31%), Gaps = 97/445 (21%)
Query: 940 PPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAP-G 998
PPG G P GL +P G + + G+P PP P G P +P P G
Sbjct: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIP--GEEGKEGRDGKPGPPGE-PGKAGEPGLPGPEG 1270
Query: 999 TRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHF 1058
R G G S AP P + G
Sbjct: 1271 ARGPPGFKGHT----------------------------GDSGAPGP----RGESGAMGL 1298
Query: 1059 RRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSL-L 1117
G G PT P PP SP SP P S E S L
Sbjct: 1299 PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358
Query: 1118 PGFGGGRGPSFRRKMGTEGSEPGEGG-----PAPGTAQQPRVHGV-ALPGLERAKG-WSF 1170
PGF G RGP EPGE G PG +P G PG++ KG
Sbjct: 1359 PGFLGPRGPP---------GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 1409
Query: 1171 DGKREGPG-PDQEGSTQAWQKRRSSDDAGPGSWKPPPPP--------QSTKPSFSAMRR- 1220
G+ PG P +G T + + GP PP PP + PS +RR
Sbjct: 1410 KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG--PPGPPGQPGFPGLRGESPSMETLRRL 1467
Query: 1221 -AEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFP--ERTLPARNAKLQDPAL---- 1273
E E Q P PA + + G P + LP R + +P
Sbjct: 1468 IQEELGKQLETRLAYLLAQMP-PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG 1526
Query: 1274 -APWPPKPVAVPRGRQ----PPQEPGVREEAEAG---------------DAAPGVNKPRL 1313
P P+ P+G + P PGV E G D PG+ P+
Sbjct: 1527 GLEGPSGPIG-PKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQ- 1584
Query: 1314 RLSSQQDQEEPEVQGPPDPGRRTAP 1338
P + GPP P + P
Sbjct: 1585 --GETGPAGHPGLPGPPGPPGQCDP 1607
Score = 48.1 bits (113), Expect = 6e-05
Identities = 132/500 (26%), Positives = 161/500 (32%), Gaps = 140/500 (28%)
Query: 935 GNLGIPPGWFSGLGGSQPTASGSWEGLSELP----THGYKLRHQTQGRPRP--PRTTPPG 988
GN G P G G S P S GL P G K +G P P PR P
Sbjct: 916 GNPGAP-GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA 974
Query: 989 PGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQ 1048
PG P P G E G L S P L T +A ++
Sbjct: 975 PGLPGPPGKGKDGEPG-----------------LRGSPGLPGPLGT------KAACGKVR 1011
Query: 1049 KKRRRGLFHFRRPRSFKGDRG----PGSPTT------GLLLPPPPPPPPTQESPPSPDPP 1098
L + KGDRG PGSP + G+ PP P PP
Sbjct: 1012 GSENCAL----GGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP----------- 1056
Query: 1099 SLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGP--APGTAQ------ 1150
G+ SP S LPGF G +GP+ R G G+ PGE GP PG +
Sbjct: 1057 --GDKGSP------GSRGLPGFPGPQGPAGRD--GAPGN-PGERGPPGKPGLSSLLSPGD 1105
Query: 1151 ------------QPRVHGV-ALPGLERAKGWSFDGKREG-------------PGPDQEGS 1184
P G+ LPG + KG REG PGP
Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG 1165
Query: 1185 TQAWQKRRSSD-------DAG----PGSWKPP--PPPQSTKPSFSAMRRAEATWHIAEES 1231
Q Q R +D D G PG PP P P A +E
Sbjct: 1166 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 1225
Query: 1232 APNHSCQS--PSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQP 1289
P S P ++G+E ++G P P K +P L P G +
Sbjct: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGP----PGEPGKAGEPGLPG--------PEGARG 1273
Query: 1290 PQEPGVREEAEAGDA-APGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTR--R 1346
P PG + GD+ APG PR P +G P T P P+ + R
Sbjct: 1274 P--PGFK--GHTGDSGAPG---PR---GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323
Query: 1347 AQSCDKLEPDRRRPPDPTGT 1366
P P P+GT
Sbjct: 1324 GPPGKNGSPGSPGEPGPSGT 1343
Score = 45.8 bits (107), Expect = 3e-04
Identities = 41/138 (29%), Positives = 52/138 (37%), Gaps = 21/138 (15%)
Query: 1081 PPPPPPPTQESPPSPDPPS---LGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGS 1137
PP +Q P P PP L + P P PG GG GPS +G +G
Sbjct: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR-----PGQGGLEGPS--GPIGPKGE 1540
Query: 1138 EPGEGGP-APGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDD 1196
+G P APG + + +PG G++ DG PGP E +
Sbjct: 1541 RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGE----------TGPA 1590
Query: 1197 AGPGSWKPPPPPQSTKPS 1214
PG PP PP PS
Sbjct: 1591 GHPGLPGPPGPPGQCDPS 1608
Score = 45.4 bits (106), Expect = 4e-04
Identities = 85/329 (25%), Positives = 114/329 (34%), Gaps = 38/329 (11%)
Query: 1070 PGSPTTGLLLPPPPPPPPTQESPPSPDPPSLG-NNSSPCWSPEEESSLLPGFGGGRG-PS 1127
P P ++ PPPPPP + PP+P +G + C P E + G G G P
Sbjct: 439 PSGPCQVTVVTEPPPPPP-PQRPPTPGSEQIGFLKTINCSCPAGEKGEM-GVAGPMGLPG 496
Query: 1128 FRRKMGTEG--------SEPGEGGPAP-GTAQQPRVHGVALPGLERAKGWSFDGKREGPG 1178
+ +G G E G+ G P G ++ + LPG G G R PG
Sbjct: 497 PKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDG--SKGMRGEPG 554
Query: 1179 PDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEE-------S 1231
E R PG P PP + P R + T E
Sbjct: 555 ELGEPGLPGEVGMR-GPQGPPG--LPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPG 611
Query: 1232 APNHSCQS--PSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQ- 1288
P + Q P P+ G + ++G + P + +Q L P PRG Q
Sbjct: 612 KPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAP--GPRGHQG 669
Query: 1289 PPQEPGVREE--AEAGDAAPGVNKPRLRLSSQQDQEEP---EVQGPPDPGRRTAPLKPKR 1343
P PG R E D PG+ R + P +QGPP P P P
Sbjct: 670 APGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGG 729
Query: 1344 TRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
+ + P + PP PTG PG D
Sbjct: 730 SPGLPG-EIGFPGKPGPPGPTG--PPGKD 755
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 57.0 bits (136), Expect = 1e-07
Identities = 134/509 (26%), Positives = 169/509 (33%), Gaps = 85/509 (16%)
Query: 925 GSPQDM--ESQLGNLGIP--PGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPR 980
G P +M Q+G G P PG G P S + +G P G R + GR
Sbjct: 1257 GEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFP--GADGRPGSPGRAG 1314
Query: 981 PPRTTPPGPGRPSMPA-PGTRQENG-MATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPG 1038
P T P PG P PG R + G R +G + + E P P
Sbjct: 1315 NPGT-PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPS 1373
Query: 1039 LSEAPLPPLQKKRRRGL-----FHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPP 1093
P PL RG + + +G+RGP P G + P P P SP
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433
Query: 1094 SPDPPSLGNNSSPCWSPEEESSLLPGFGGG------RGP----------SFRRKMGTEGS 1137
P E+ + LPG G RGP F +G E
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG-EAG 1492
Query: 1138 EPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDA 1197
E GE GP PG A + GVA G AKG EGP + + R D A
Sbjct: 1493 EKGERGP-PGPAGSRGLPGVA--GRPGAKG------PEGPPGPTGRQGEKGEPGRPGDPA 1543
Query: 1198 GPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQ-SPSPASQDGEEEKEGTLF 1256
G P+ K AT E P P P G+ G
Sbjct: 1544 VVG--PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG--L 1599
Query: 1257 PERTLPARNA----KLQDPALAPWPPKPVAVPRGRQ----------PPQEPGVREEA-EA 1301
R P ++ + DP P PP PV PRGR PP +PG+ +A E
Sbjct: 1600 TGRAGPPGDSGPPGEKGDPG-RPGPPGPVG-PRGRDGEVGEKGDEGPPGDPGLPGKAGER 1657
Query: 1302 G-DAAPGVNKPRLRLSSQQDQEEPEVQ------------------GPPDPGRRTAPLKPK 1342
G APGV P + + DQ +P GPP P R P
Sbjct: 1658 GLRGAPGVRGP---VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714
Query: 1343 RTRRAQSCDKLEPDRRRPP-DPTGTSEPG 1370
+ + D+ + R P DP PG
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPG 1743
Score = 42.4 bits (98), Expect = 0.003
Identities = 85/328 (25%), Positives = 110/328 (33%), Gaps = 37/328 (11%)
Query: 1065 KGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSL----LPGF 1120
KG+RG G+L P PP P PP P + + P E S LPG
Sbjct: 1874 KGERG----APGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE 1929
Query: 1121 GGGRG-----PSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKRE 1175
G RG P+ R + T G + T + G LP ER +G D +
Sbjct: 1930 RGLRGEPGSVPNVDRLLETAGIKASALREIVETWDES--SGSFLPVPERRRGPKGDSGEQ 1987
Query: 1176 GPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNH 1235
GP P +EG +R D G P PQ R +A E
Sbjct: 1988 GP-PGKEGPIGFPGERGLKGDRG------DPGPQGPPGLALGERGPPGPSGLAGEPGKPG 2040
Query: 1236 SCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQD-PALAPWPPKPVAVPRGRQPPQEPG 1294
P A GE + G R + +D P P P P P + EPG
Sbjct: 2041 IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG 2100
Query: 1295 VREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPP-------DPGRRTAPLKPKRT-RR 1346
E G PG+ + S DQ +G P +PG R P R
Sbjct: 2101 PGLSGEQG--PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGER 2158
Query: 1347 AQSCDKLEP---DRRRPPDPT-GTSEPG 1370
+ + +P R PP P G +PG
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVGGHGDPG 2186
Score = 40.0 bits (92), Expect = 0.015
Identities = 42/130 (32%), Positives = 49/130 (37%), Gaps = 20/130 (15%)
Query: 1059 RRPRSFKGDRG-------PGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPE 1111
R R KG+RG PG P T P PP PP + S P P G P
Sbjct: 2060 RGERGEKGERGEQGRDGPPGLPGT----PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA 2115
Query: 1112 EESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGP--APGTAQQPRVHGVALPGLERAKGWS 1169
+ PG G +GP R + + GE GP G P G+A G E G
Sbjct: 2116 KGE---PGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA--GPEGKPG-- 2168
Query: 1170 FDGKREGPGP 1179
G R PGP
Sbjct: 2169 LQGPRGPPGP 2178
Score = 38.9 bits (89), Expect = 0.034
Identities = 103/412 (25%), Positives = 136/412 (33%), Gaps = 95/412 (23%)
Query: 976 QGRPRPPRTT-PPGPGRPSMPA----PGTRQENGMATRLDEGLEDFFSRRVLEESSSYPR 1030
QG P P PPG G P +P G R E G ++ ++GL R + E S P
Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETG--SKGEQGLPG--ERGLRGEPGSVPN 1941
Query: 1031 TLRTVRP-GLSEAPLPPLQKKRRRGLFHF----RRPRSFKGDRGPGSPTTGLLLPPPPPP 1085
R + G+ + L + + F R R KGD G
Sbjct: 1942 VDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSG---------------- 1985
Query: 1086 PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPA 1145
++ PP + P P E L G G GP G G GE GP
Sbjct: 1986 ---EQGPPGKE--------GPIGFPGERG--LKGDRGDPGPQ-----GPPGLALGERGPP 2027
Query: 1146 --PGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWK 1203
G A +P G+ PGL G + R G ++ + ++ R PG+
Sbjct: 2028 GPSGLAGEPGKPGI--PGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085
Query: 1204 PPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPA--SQDGEEEKEGTLFP--ER 1259
PP PP P S +E P S + P GE G P +R
Sbjct: 2086 PPGPP---GPKVS-----------VDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDR 2131
Query: 1260 TLPARNAKLQDPALAPWPPKPVAVPRGRQ-PPQEPGVREEAEAGDAAPGVNKPRLRLSSQ 1318
+P +P PRG+ P PG R A + PG+ PR
Sbjct: 2132 GVPGIKGDRGEPG-----------PRGQDGNPGLPGERGMA-GPEGKPGLQGPRGPPGPV 2179
Query: 1319 QDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPP-----DPTG 1365
+P GPP P P + S K EP PP PTG
Sbjct: 2180 GGHGDP---GPPGAPGLAGPAGP----QGPSGLKGEPGETGPPGRGLTGPTG 2224
Score = 38.1 bits (87), Expect = 0.058
Identities = 71/294 (24%), Positives = 99/294 (33%), Gaps = 51/294 (17%)
Query: 1068 RGPGSPTTGLLLPPPPPPP---PTQESPPSP-------DPPSLGNNSSPCWSPEEESSLL 1117
RG PT + LP PP P Q SP P P + G + + + S +
Sbjct: 2217 RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGV 2276
Query: 1118 PGFGGGRGP---------------SFRRKMGTEGSEPGEGGPAPGTAQQPRVHG-VALPG 1161
PG G GP + G +G + GG A +P G LPG
Sbjct: 2277 PGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPG 2336
Query: 1162 LERAKGWSFDGKREGPG-PDQEGSTQAWQKRRSSDDAG---PGSWKPP-PPPQSTKPSFS 1216
KG + G+ PG P ++G A + D G PGS PP PP
Sbjct: 2337 PRGEKGEA--GRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP 2394
Query: 1217 AMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPW 1276
+ A ++ P P P+ GE G P + P P
Sbjct: 2395 GLPGAPGVVGFPGQTGPRGEMGQPGPS---GERGLAG--------PPGREGIPGPLGPPG 2443
Query: 1277 PPKPVAVPRGRQPPQEPGVR-EEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGP 1329
PP V PP G++ ++ + G PG R + + P +GP
Sbjct: 2444 PPGSVG------PPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGP 2491
Score = 36.6 bits (83), Expect = 0.17
Identities = 42/130 (32%), Positives = 47/130 (36%), Gaps = 28/130 (21%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGF 1120
P+ FKGD G G P + P PP PP + P P + GF
Sbjct: 2364 PKGFKGDPGVGVPGS----PGPPGPPGVKGDLGLPGLPGAPG--------------VVGF 2405
Query: 1121 GGGRGPSFRRKMGTEG--SEPGEGGP-----APGTAQQPRVHG-VALPGLERAKGWSFDG 1172
G GP R +MG G E G GP PG P G V PG KG D
Sbjct: 2406 PGQTGP--RGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP 2463
Query: 1173 KREGPGPDQE 1182
PGP E
Sbjct: 2464 GVGLPGPRGE 2473
Score = 33.9 bits (76), Expect = 1.1
Identities = 112/426 (26%), Positives = 139/426 (32%), Gaps = 95/426 (22%)
Query: 927 PQDMESQLGNLGIP--PG--WFSGLGG-----SQPTASGSWEGLSELPTHGYKLRHQTQG 977
P ++ LG G+P PG F G G QP SG GL+ P G + G
Sbjct: 2384 PPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE-RGLAGPP--GREGIPGPLG 2440
Query: 978 RPRPPRTT-PPGP-------GRPSMPAPGTRQENGM-ATRLDEGLEDFFSRRVLE----- 1023
P PP + PPG G P + PG R E G R ++G R L
Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500
Query: 1024 -----ESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLL 1078
E G S L P + +G R PR GD+GP
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRG------ 2554
Query: 1079 LPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSE 1138
+ DP G+ P ++ S+ LPG G GP +
Sbjct: 2555 --------------DNGDPGDKGSKGEP---GDKGSAGLPGLRGLLGPQ---------GQ 2588
Query: 1139 PGEGGPAPGTAQQPRVHGVALPGLERAKG-WSFDGKREGPGPDQEGSTQAWQKRRSSDDA 1197
PG G PG P GV PG+ KG F G R G + G A D
Sbjct: 2589 PGAAG-IPGDPGSPGKDGV--PGIRGEKGDVGFMGPRGLKG--ERGVKGACGLDGEKGDK 2643
Query: 1198 GPGSWKPPPPP-------QSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEE 1250
G PP P + +P A + P P GE+
Sbjct: 2644 GEAG--PPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701
Query: 1251 KEGTL----FPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQ----EPGVREEAEAG 1302
+ GT FP P+ N P P PP V PRG + Q E G E G
Sbjct: 2702 ERGTPGIGGFPG---PSGNDGSAGP---PGPPGSVG-PRGPEGLQGQKGERGPPGERVVG 2754
Query: 1303 DAAPGV 1308
APGV
Sbjct: 2755 --APGV 2758
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 57.0 bits (136), Expect = 1e-07
Identities = 110/441 (24%), Positives = 146/441 (33%), Gaps = 80/441 (18%)
Query: 976 QGRPRPPRTTPPGP-------------GRPSMPAPGTRQENGMATRLDEGLEDFFSRRVL 1022
+G P PP TPP P P P + + + AT L +G L
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT-TPAATL 1064
Query: 1023 EESSSYPRTLRTVRPGLSEAPLPP------------LQKKRRRGLFHFRRPRSFKGDRG- 1069
P T P L AP PP + + P S KG
Sbjct: 1065 PSPKGGPAT-----PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 1070 ---PGSPTTGLLLPPPP------PPP---PT--QESPPSP-----DPPSLGNNSSPCWSP 1110
G+PTT PP P PPP PT +PPSP PP G ++P +P
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 1111 EEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAP-GTAQQPRVHGVALPGLERAKGWS 1169
GG PS + T + P P+P G P G P A S
Sbjct: 1180 PSPK------GGLATPSPKGAPTTPAATP----PSPKGGLATPSPKGA--PTTPAATPPS 1227
Query: 1170 FDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP---PPPPQSTKPSFSAMRRAEATWH 1226
G P P +T A S GP + P P PP +T PS ++ AT
Sbjct: 1228 PKGGLATPSPKGAPTTPA--ATPPSPKGGPATPPPKGAPTPPAATPPS---LKGGLAT-- 1280
Query: 1227 IAEESAPNHSCQS-PSPASQDGEEEKEGTLFPERTLPAR---NAKLQDPALAPWPPKPVA 1282
+ APN + + PSP +G P P + P AP PP V
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP-AVT 1339
Query: 1283 VPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPK 1342
P + P P ++ G P + ++ + PP P R A PK
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
Query: 1343 RTRRAQSCDKLEPDRRRPPDP 1363
+ + L P ++ P P
Sbjct: 1400 GDPTSPAVIPLSP-KKAPATP 1419
Score = 55.8 bits (133), Expect = 3e-07
Identities = 103/429 (24%), Positives = 136/429 (31%), Gaps = 105/429 (24%)
Query: 976 QGRPRPPRTTPPGP-GRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRT 1034
+G P PP TPP P G P+ P+P AT P T
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP--------------PSPKGGPAT--- 979
Query: 1035 VRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGP------GSPTTGLLLPPPP----- 1083
P AP PP P S KG GP G+PT + PP P
Sbjct: 980 --PSPKGAPTPPAAT-----------PPSPKG--GPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 1084 --PPPPTQESPPSPDPPSLGNNSS----PCWSPEEESSLLPGFGGGRG-PSFRRKMGTEG 1136
P P +PP+ PPS + + P +P ++ LP GG PS +
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK------- 1077
Query: 1137 SEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDD 1196
G P P A P G P KG P P +T + ++
Sbjct: 1078 -----GAPTPPAATPPSPKGG--PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 1197 AGPGSWK-----PPPP-----PQSTKPS-----FSAMRRAEATWHIAEESAPNHSCQSPS 1241
A P S K PPP P +T PS + + T A +P +PS
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 1242 PASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEA 1301
P K P T P+ L P+ P P A P P + G+ +
Sbjct: 1191 P--------KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP----PSPKGGLATPSPK 1238
Query: 1302 G-DAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRP 1360
G P P + GP P + AP P T + P +
Sbjct: 1239 GAPTTPAATPPSPK------------GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
Query: 1361 PDPTGTSEP 1369
P+P + P
Sbjct: 1287 PNPAVVTPP 1295
Score = 55.1 bits (131), Expect = 5e-07
Identities = 119/501 (23%), Positives = 163/501 (32%), Gaps = 116/501 (23%)
Query: 940 PPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGP---------- 989
PP GL P + + + G +G P P TPP P
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 990 GRPSMP-APGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPP-- 1046
G P+ P A + G+AT +G P T P AP PP
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGPAT-----PPPKGAPTPPAA 1269
Query: 1047 --------LQKKRRRGLFH--FRRPRSFKGDRGP------GSPTTGLLLPPPP------P 1084
L +G + P S KG GP G+PT PP P P
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKG--GPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 1085 PPPTQESPPSPDPPS-LGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG-EG 1142
PP +PP+ PPS G + P +P + GG PS + + P +G
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSK-------GGPTTPSSKEGPTPPAATPSHKG 1380
Query: 1143 GPAPGTAQQPRVHGVALPG------------LERAKGWSFDGKREGPGPDQEGS------ 1184
GPA T P+ G A+P L K + REG +G
Sbjct: 1381 GPAM-TPPSPK-RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 1185 TQAWQKRRSSDDA-------------------GPGSWKPPPPPQSTKPSFSAMRRAEATW 1225
T K+ + A P S K PP P+ S S+ ++A AT
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS-SSPKKAPAT- 1496
Query: 1226 HIAEESAPNHSCQSPS--------PASQDGEEEKEGTLFPER---TLPARNAKLQDPALA 1274
A AP PS P+S+ TL ++ TL + A +
Sbjct: 1497 -PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 1275 PWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNK-----------PRLRLSSQQDQEE 1323
P P K A+P ++ P P +E + P K P + S ++
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 1324 PEVQGPPDPGRRTAPLKPKRT 1344
P PP P + A PK T
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGT 1636
Score = 51.2 bits (121), Expect = 7e-06
Identities = 97/417 (23%), Positives = 134/417 (32%), Gaps = 64/417 (15%)
Query: 976 QGRPRPPRTTPPGP----------GRPSMP-APGTRQENGMATRLDEGLEDFFSRRVLEE 1024
+G P PP TPP P G P+ P A + G+AT +G +
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG-----APTTPAA 1154
Query: 1025 SSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRG--PGSPTTGLLLPPP 1082
+ P+ P P +G P+ P SP GL P P
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
Query: 1083 PPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEG 1142
P T + P P P SP +P ++ P GG + P +G
Sbjct: 1215 KGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGG-----------PATPPPKG 1262
Query: 1143 GPAPGTAQQPRVH-GVALP---GLERAKGWSFDGKREGPGPD-QEGSTQAWQKRRSSDDA 1197
P P A P + G+A P G + + GP +G+ S
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 1198 GPGSWKP---PPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
PG+ P P PP T PS AT P+ +P+S++G T
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPAT-------TPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 1255 LF----PERTLPARNAKLQDPALAPWPPKPVAVPRG-RQPPQEPGVREEA---EAGDAAP 1306
P T P+ P+ P P +P ++ P P RE A GD P
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 1307 GVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDP 1363
P + L P+ GP P + P P T P + PP P
Sbjct: 1436 PAVTP-VSLKKAPATSAPK-GGPATPSSKGDPTLPAVT---------PPSPKEPPAP 1481
Score = 48.1 bits (113), Expect = 6e-05
Identities = 81/336 (24%), Positives = 111/336 (33%), Gaps = 64/336 (19%)
Query: 1076 GLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLP----GFGGGRGPSFRRK 1131
G+ + P PPT++ PD P +GN SSP SP E+S LP F G +
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTP-IGNLSSPV-SP-VEASFLPENSLSFQGSKDSPATTH 854
Query: 1132 MGTEGSEPGEGGPAPGTAQQPRVHGVALPGLER-----------AKGWSFDGKREGP--- 1177
T S G P+ T P+ GV LP E +G + ++ P
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPK--GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 1178 --------------------GPDQEGSTQAWQKRRSSDDAGPGSWKP---PPPPQSTKPS 1214
P +G+ S GP + P P PP +T PS
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 1215 FSAMRRAEATWHIAEESAPN-HSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPAL 1273
+ AT + + AP + PSP +G P P + PA
Sbjct: 973 ---PKGGPAT--PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP--SPKGSPAA 1025
Query: 1274 APWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPG 1333
P+ PK + P PP G AP P L S + GP P
Sbjct: 1026 TPF-PKGASTPPAATPPSPKGSPAATPLPKGAP--TTPAATLPSPKG-------GPATPS 1075
Query: 1334 RRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
+ AP P T + P + P P + P
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Score = 41.2 bits (95), Expect = 0.007
Identities = 74/337 (21%), Positives = 101/337 (29%), Gaps = 54/337 (16%)
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPD 1096
P E P P K+ P+ + P G+ P P PT + P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAP----KGIPASPSPKGAPTPPAATPPS 949
Query: 1097 PPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHG 1156
P SP W+P ++ P GG + +G P P A P G
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGG-----------PATPSPKGAPTPPAATPPSPKG 998
Query: 1157 VALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFS 1216
P KG P P + + K S+ P + PP P S P+ +
Sbjct: 999 G--PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST----PPAATPPSPKGS--PAAT 1050
Query: 1217 AMRRAEATWHIAEESAPNHSCQSPS------PASQDGEEEKEGTLFPERTLPARNAKLQD 1270
+ + T A +P +PS P + K G P + A +
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS----PKGAPMPP 1106
Query: 1271 PALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPP 1330
A P P +A P + P P A P K L + PP
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPA---------ATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 1331 DP--GRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTG 1365
P G T P K T A + PP P G
Sbjct: 1158 SPKGGLATPPPKGAPTTPAAT----------PPSPKG 1184
Score = 33.5 bits (75), Expect = 1.4
Identities = 54/254 (21%), Positives = 89/254 (35%), Gaps = 20/254 (7%)
Query: 1060 RPRSFKGDRGPGSPTTGLLLPPPPPP-PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLP 1118
+P S P P + L P P P PP Q+ PS L + S P +P +E LLP
Sbjct: 1784 KPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL-APADEDELLP 1842
Query: 1119 GFGG---GRGPSFRRKMGTEGSEPGEGGPAP-GTAQQPRVHGVALPGLERAKGWSFDGKR 1174
G F+ + + G P P +A+QP + G D
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKN------NKGSGTESDSDE 1896
Query: 1175 EGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSA--------MRRAEATWH 1226
P +++ STQA ++ A +P + ++ A +R+
Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTR 1956
Query: 1227 IAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG 1286
+ + N P +F E + + + Q A + + AV
Sbjct: 1957 VTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNI 2016
Query: 1287 RQPPQEPGVREEAE 1300
++ Q P V+EE+E
Sbjct: 2017 QENTQTPTVQEESE 2030
Score = 32.0 bits (71), Expect = 4.2
Identities = 86/396 (21%), Positives = 139/396 (35%), Gaps = 71/396 (17%)
Query: 975 TQGRPRPPRTTPPGPGRPSMPA------------PGTRQEN--GMATRLDEGLEDFFSRR 1020
T P+ TP G P++PA P +R++ AT L + + +
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 1021 --VLEESSSYPRTLRTVR-PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGL 1077
++ + + P +T P EAP P K+ P ++KG P L
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP--PAVTPSTYKGAPSPKE----L 1599
Query: 1078 LLPP----------PPPP---PPTQESPPSPDPPSLGNNSSPCWSPE--EESSLLPGFGG 1122
L+PP P PP PP+ E P+ P G +SP +P ++S P
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSPTSPA--- 1655
Query: 1123 GRGPSFRRKMGTEGSEPGEGGPA-PGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQ 1181
S KMG + +G PA G V + P E + R+GP +
Sbjct: 1656 ----SVTCKMGATVPQASKGLPAKKGPTALKEV--LVAPAPESTPIITAP-TRKGPQTKK 1708
Query: 1182 EGSTQ---AWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQ 1238
+T + GP S P P + S + + H + +
Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
Query: 1239 SPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAV--PRGRQPPQEPGVR 1296
+ +P + E+ + P+ + +A P P P PV P+ + P PG+
Sbjct: 1769 ASTPLTAAAFEK----VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV 1824
Query: 1297 EEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDP 1332
E+ + AP D++E PP+P
Sbjct: 1825 LESPSKPLAPA------------DEDELLPLIPPEP 1848
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 56.6 bits (135), Expect = 2e-07
Identities = 94/317 (29%), Positives = 112/317 (35%), Gaps = 44/317 (13%)
Query: 1065 KGDRGP-GSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGG 1123
KGD G G P + PP P + +P G P S PG G
Sbjct: 442 KGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGV 501
Query: 1124 RGPSFRRKMGTEGSEPGEGGP--APGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQ 1181
GP + G GS PG GP +PG A +P G LPG AKG G PGPD
Sbjct: 502 AGP--KGPAGERGS-PGPAGPKGSPGEAGRPGEAG--LPG---AKG--LTGSPGSPGPDG 551
Query: 1182 EGSTQAWQKRRSSDDAGPGSWKPPPPP----QSTKPSFSAMRRAEATWHIAEESAPNHSC 1237
+ + D PG PP PP Q+ F + A A E
Sbjct: 552 KTGPPG----PAGQDGRPG---PPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604
Query: 1238 QSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAP---WPPKPVAVPRGRQPPQEPG 1294
+ PA +DGE +G P PA Q PA +P P P P P E G
Sbjct: 605 GAVGPAGKDGEAGAQGP--PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQG 662
Query: 1295 VREEAEAGD-AAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKL 1353
V GD APG + R + E VQGPP P P+ A D
Sbjct: 663 V-----PGDLGAPGPSGAR---GERGFPGERGVQGPP------GPAGPRGANGAPGNDGA 708
Query: 1354 EPDRRRPPDPTGTSEPG 1370
+ D P P PG
Sbjct: 709 KGDAGAPGAPGSQGAPG 725
Score = 53.9 bits (128), Expect = 1e-06
Identities = 104/415 (25%), Positives = 139/415 (33%), Gaps = 85/415 (20%)
Query: 986 PPGPGRPSMP--------APGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP 1037
PPGP P+ P APG + G A ++ +P V P
Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSAGP--------------PGATGFPGAAGRVGP 885
Query: 1038 ----GLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPT--TGLLLPPPPPPPPTQES 1091
G + P PP + G KG RG P G + PP PP P ++
Sbjct: 886 PGPSGNAGPPGPPGPAGKEGG----------KGPRGETGPAGRPGEVGPPGPPGPAGEKG 935
Query: 1092 PPSPDPPSLGNNSSPCWSPEEESSL-----LPGFGGGRGPSFRRKMGTEGSEPGEGGPAP 1146
P D P+ G +P P+ + LPG G RG F G G EPG+ GP+
Sbjct: 936 SPGADGPA-GAPGTP--GPQGIAGQRGVVGLPGQRGERG--FPGLPGPSG-EPGKQGPSG 989
Query: 1147 GTAQQPRVHGVALPGLERAKGWSFDGKREGPG----PDQEGSTQAWQKRRSSDDAG-PGS 1201
+ ++ + PGL G S G+ PG P ++GS A R + AG PG+
Sbjct: 990 ASGERGPPGPMGPPGLAGPPGES--GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047
Query: 1202 WKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTL 1261
P P P+ + R E A + P + PA G +G +
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGET--GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDR 1105
Query: 1262 PARNAK----LQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSS 1317
+ + LQ P P P P G P P + G+N
Sbjct: 1106 GIKGHRGFSGLQGPPGPPGSPGEQG-PSGASGPAGPRGPPGSAGAPGKDGLN-------- 1156
Query: 1318 QQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD 1372
P GPP P RT P P PP P G G D
Sbjct: 1157 ----GLPGPIGPPGPRGRTGDAGPVG----------PPGPPGPPGPPGPPSAGFD 1197
Score = 52.0 bits (123), Expect = 4e-06
Identities = 83/294 (28%), Positives = 106/294 (36%), Gaps = 47/294 (15%)
Query: 1065 KGDRGP----GSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGF 1120
KG+ GP GS + P PP P + P+ +P + G + + + PGF
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411
Query: 1121 GGGRGPSFRRKMGTEGSEPGEGGPAP-GTAQQPRVHGVALPGLERAKGWSFD-GKREGPG 1178
G RGPS G +G PG G P P G + +P G G AKG G + PG
Sbjct: 412 PGARGPS-----GPQG--PG-GPPGPKGNSGEPGAPG--SKGDTGAKGEPGPVGVQGPPG 461
Query: 1179 P-DQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSC 1237
P +EG KR + + GP + P PP + P A+ +A P
Sbjct: 462 PAGEEG------KRGARGEPGP-TGLPGPPGERGGPGSRGFPGADG---VAGPKGPAGER 511
Query: 1238 QSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPAL-----APWPPKPVAVPRGRQPPQE 1292
SP PA G + G E LP P PP P PP
Sbjct: 512 GSPGPAGPKGSPGEAGRP-GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570
Query: 1293 PGVREEA-------------EAGDAAP-GVNKPRLRLSSQQDQEEPEVQGPPDP 1332
PG R +A E G A GV P + E QGPP P
Sbjct: 571 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624
Score = 49.3 bits (116), Expect = 3e-05
Identities = 87/371 (23%), Positives = 118/371 (31%), Gaps = 103/371 (27%)
Query: 1065 KGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSP--CWSPEEESS------- 1115
+G RGP P +P P P P P PP LG N +P + +E+S+
Sbjct: 120 RGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG 179
Query: 1116 --------LLPGFGGGRGPSFRRKMGTEGSEPGEGGP----------------------- 1144
LPG G GP + E EPG GP
Sbjct: 180 PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239
Query: 1145 APGTAQQPRVHG-------VALPGLERAKGWS-FDG----------KREGPGPDQEGSTQ 1186
PG P G LPG++ +G+S DG K E P + G+
Sbjct: 240 RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPG 299
Query: 1187 AWQKR-----------------RSSDDAGPGSWKPPPPPQSTKPSF------------SA 1217
R R +D A + P P + P F
Sbjct: 300 QMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQG 359
Query: 1218 MRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWP 1277
R +E + E P + PA G + + G A+ A P +A P
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG---------AKGAN-GAPGIAGAP 409
Query: 1278 PKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDP----G 1333
P A RG PQ PG + PG + ++ + VQGPP P G
Sbjct: 410 GFPGA--RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEG 467
Query: 1334 RRTAPLKPKRT 1344
+R A +P T
Sbjct: 468 KRGARGEPGPT 478
Score = 43.9 bits (102), Expect = 0.001
Identities = 97/397 (24%), Positives = 125/397 (31%), Gaps = 109/397 (27%)
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGP----GSP-------TTGLLLPPPPPP 1085
PGL P RG P+ +GD GP GSP TG + PP P
Sbjct: 724 PGLQGMP-------GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG 776
Query: 1086 PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPA 1145
P + P P+ GP+ R + EPG GPA
Sbjct: 777 APGDKGESGPSGPA-------------------------GPTGARGAPGDRGEPGPPGPA 811
Query: 1146 -----PGTAQQPRVHGVALPGLERAKGWSFDGKREGPG--PDQEGSTQAWQKRRSSDDAG 1198
PG QP G PG AKG + GP P G+ A + + AG
Sbjct: 812 GFAGPPGADGQPGAKGE--PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG 869
Query: 1199 P-------------------GSWKPPPPPQSTKPSFSAMRRAEA-----TWHIAEESAPN 1234
P G+ PP PP R E + P
Sbjct: 870 PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG 929
Query: 1235 HSCQSPSPASQDGEEEKEGTLFPERT--------LPARNAKLQDPAL------------- 1273
+ + SP + DG GT P+ LP + + P L
Sbjct: 930 PAGEKGSPGA-DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988
Query: 1274 ----APWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGP 1329
PP P+ P PP E G RE A + +PG + ++ D+ E GP
Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESG-REGAPGAEGSPGRDGSP---GAKGDRGETGPAGP 1044
Query: 1330 PDPGRRTAPLKPKRTRRA-QSCDKLEPDRRRPPDPTG 1365
PG AP P A +S D+ E P P G
Sbjct: 1045 --PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG 1079
Score = 37.4 bits (85), Expect = 0.100
Identities = 102/418 (24%), Positives = 131/418 (31%), Gaps = 44/418 (10%)
Query: 977 GRPRPP-RTTPPGP----GRPSMPAP-GTRQENGMATRLDEGLEDFFSRRVLEESSSYPR 1030
G P P +T PPGP GRP P P G R + G+ G + P
Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF--PGPKGAAGEPGKAGERGVPG 602
Query: 1031 TLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQE 1090
V P + G P +G++GP LP P PP
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAG------PAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656
Query: 1091 SPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGP-------SFRRKMGTEGSEPGEGG 1143
P P G+ +P S PG G +GP G +G++ G
Sbjct: 657 KPGEQGVP--GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714
Query: 1144 P-APGTAQQPRVHGVALPGLERAKGW-SFDGKREGPGP-DQEGSTQAWQKRRSSDDAG-P 1199
P APG+ P + G +PG A G G R GP +GS R + G P
Sbjct: 715 PGAPGSQGAPGLQG--MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772
Query: 1200 GSWKPPPPPQSTKPSFSA-MRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPE 1258
G P + PS A A E P P DG+ +G P
Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE--PG 830
Query: 1259 RTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQ 1318
+A PA PP P+ P G R A A G R+
Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIG---NVGAPGAKGARGSA-GPPGATGFPGAAGRVGPP 886
Query: 1319 QDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTS----EPGTD 1372
GPP P + P R ++ P PP P G + PG D
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGP----RGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 56.6 bits (135), Expect = 2e-07
Identities = 106/454 (23%), Positives = 150/454 (33%), Gaps = 61/454 (13%)
Query: 950 SQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRL 1009
S P S + L E P L + P P TP P + P +E+ ++
Sbjct: 504 SPPPESSPFSPLEESP-----LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558
Query: 1010 DEGLEDFFSRRVLEESS--SYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGD 1067
+E E+S S P + P E+P+ P + R P S +
Sbjct: 559 EE-----LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
Query: 1068 RGPGSPT--TGLLLPPP---PPPPPTQESPPSPDPPSLGNNS--------------SPCW 1108
P SP L PPP P PP +ESP SP PP + S SP
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP-PPEVSRLSPLPVVSRLSPPPEESPLS 672
Query: 1109 SPEEESSLLPGFGGGR---GPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERA 1165
P EES P R P P P P LP E
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 1166 KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATW 1225
+ + EGP R P + +P PQ +P A+
Sbjct: 733 Q---LCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP--- 786
Query: 1226 HIAEESAPNHSCQSP-----SPASQD------------GEEEKEGTLFPERTLPARNAKL 1268
H++ ++ H P SP +++ + +E L P+ P + +
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 1269 QDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLR-LSSQQDQEEPEVQ 1327
++ L+P KP PR +PP+EPG E P +P L L + EP +
Sbjct: 847 EESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG-E 905
Query: 1328 GPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPP 1361
P P PL P + S + PD PP
Sbjct: 906 PPLSPLPEELPLSPS-GEPSLSPQLMPPDPLPPP 938
Score = 42.4 bits (98), Expect = 0.003
Identities = 93/427 (21%), Positives = 133/427 (31%), Gaps = 97/427 (22%)
Query: 976 QGRPRPPRTTPPGPGRPS--------MPAPGTRQENGMATRLDEGL-------EDFFSRR 1020
QG+P+ T P P + G + E + L+E + E S
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP 452
Query: 1021 VLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP 1080
E +S P + P E P PL + H RP P
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEA-----LHLSRPLEES--------------P 493
Query: 1081 PPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGF---------GGGRGPSFRRK 1131
PPP + SPP P SP SP EES P P F
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPL-SPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 1132 MGTEGSEPGEGGPAPGTAQ-----------QPRVHGVALPGLERAKGW-SFDGKREGPGP 1179
+ E P P ++ P P E ++ + F+ P P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
Query: 1180 DQEGSTQAWQKRRSSDDAGPGSWKPPP--PPQSTKPSFSAMRRAEATWHIA---EES--- 1231
++ + + R S PPP P S P S + ++ EES
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672
Query: 1232 -APNHSCQSP----------------------SPASQDGEEE------KEGTLFPERTLP 1262
P S SP SPAS E+ +E L P P
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 1263 ARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQE 1322
+ + P L+P P +P PR P+EP + +AE +P +P L ++
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPR----PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 1323 EPEVQGP 1329
P+ +GP
Sbjct: 789 SPQAEGP 795
Score = 41.2 bits (95), Expect = 0.007
Identities = 88/334 (26%), Positives = 120/334 (35%), Gaps = 29/334 (8%)
Query: 982 PRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSR-RVLEESSSYPRTLRTVRPGLS 1040
P PP RP P P E+ A D FSR +S S ++ T RP +
Sbjct: 2377 PYAQPPLTPRPQPPPP----ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
Query: 1041 EAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSL 1100
EA P R + + RP S R P +P L PP P PP S SL
Sbjct: 2433 EAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP---LHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 1101 GNNSSPCWSPEEESSLLPG-FGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHG--- 1156
G P P + L G+ P+F R GT G P+P P+ G
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAF---VGTPSPMRFTFPQAVGEPS 2546
Query: 1157 ----VALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTK 1212
V PGL G + GPGP G Q+ ++ + P P ST
Sbjct: 2547 LKPPVPQPGLPPPHGIN---SHFGPGPTL-GKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
Query: 1213 PSF--SAMRRAEATWHIAEE-SAP--NHSCQSPSPASQDGEE-EKEGTLFPERTLPARNA 1266
S+ S +R A + S P +H S + E+ E GT A
Sbjct: 2603 ESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662
Query: 1267 KLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAE 1300
QDP ++ + R RQ +E +R++ +
Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQ 2696
Score = 36.6 bits (83), Expect = 0.17
Identities = 55/231 (23%), Positives = 79/231 (34%), Gaps = 25/231 (10%)
Query: 918 PVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQG 977
P+S I+ + S LG L P F G S P + + + E P + T
Sbjct: 938 PLSPIITAAAPPALSPLGELEYP---FGAKGDSDPESPLA-APILETPISPPPEANCTDP 993
Query: 978 RPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRP 1037
P PP PP PG P PA E L ++ ++S + P
Sbjct: 994 EPVPPMILPPSPGSPVGPASPILME-----PLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048
Query: 1038 GLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDP 1097
+PL P+ K G+ + ++ P P + S SP P
Sbjct: 1049 LSVPSPLSPIGKV--VGVSDEAELHEMETEK-----------VSEPECPALEPSATSPLP 1095
Query: 1098 PSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGT 1148
+G+ S P SP G G P + GS+P E G PG+
Sbjct: 1096 SPMGDLSCPAPSPAPALDDFSGLGEDTAP--LDGIDAPGSQP-EPGQTPGS 1143
Score = 34.7 bits (78), Expect = 0.65
Identities = 66/263 (25%), Positives = 89/263 (33%), Gaps = 33/263 (12%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPPPP------TQESPPSPDPPSLGNNSSPCWSPEEES 1114
P KGD P SP +L P PPP + PP PPS G+ P SP
Sbjct: 960 PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPA-SPILME 1018
Query: 1115 SLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKR 1174
L P P + + + S P + P ALP L S GK
Sbjct: 1019 PLPPQC----SPLLQHSLVPQNSPPSQCSPP------------ALP-LSVPSPLSPIGKV 1061
Query: 1175 EGPGPDQEGSTQAWQKRRSSDDAG--PGSWKPPPPPQS--TKPSFSAMRRAEATWHIAEE 1230
G + E +K + P + P P P + P+ S + + E+
Sbjct: 1062 VGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121
Query: 1231 SAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPP 1290
+AP +P + G + G+L E L L LAP P V P +Q
Sbjct: 1122 TAPLDGIDAPGSQPEPG--QTPGSLASE--LKGSPVLLDPEELAPVTPMEV-YPECKQTA 1176
Query: 1291 QEPGVREEAEAGDAAPGVNKPRL 1313
+ EE E A P L
Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTL 1199
Score = 34.3 bits (77), Expect = 0.84
Identities = 44/173 (25%), Positives = 66/173 (38%), Gaps = 25/173 (14%)
Query: 1172 GKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEES 1231
G+ EGPG ++G S D GP K + P ++ + + + +ES
Sbjct: 4833 GEAEGPGGKEKGL------EGKSPDTGPDWLKQF---DAVLPGYTLKSQLDILSLLKQES 4883
Query: 1232 APNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQ 1291
+P P +Q + L R P PP P+A P PP
Sbjct: 4884 P------APEPPTQ------HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA-PSPASPPT 4930
Query: 1292 EPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQG-PPDPGRRTAPLKPKR 1343
EP V E A P V P L L+S + P+ + PP+ G + P + K+
Sbjct: 4931 EPLVELPTEP-LAEPPVPSP-LPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
Score = 33.1 bits (74), Expect = 1.9
Identities = 53/210 (25%), Positives = 78/210 (37%), Gaps = 43/210 (20%)
Query: 974 QTQGRPRPPRTTP---PGPGRPS---MPAPG------------TRQENGMATRLDEGLED 1015
Q P+PP+ P G G P MP G Q ++ + + L+
Sbjct: 4165 QNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224
Query: 1016 FFSRRVLEESSSYPRTLRTVRPGLSEAPL-------------PPLQKKRRRGLFHFRRPR 1062
+R L++S + +T PG +PL P Q + L RP+
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284
Query: 1063 SF-KGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPS-LGNNSSPCWSPEEESSLLPGF 1120
+ PG+ +TG +L P P PP SP P PS L + SS + + PG
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPP-PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
Query: 1121 GGGRGPSFRRKMGTEGSEPGEGGPAPGTAQ 1150
+GP+ EP G +P AQ
Sbjct: 4344 PKPQGPTL---------EPPPGRVSPAAAQ 4364
Score = 31.2 bits (69), Expect = 7.1
Identities = 73/306 (23%), Positives = 101/306 (33%), Gaps = 58/306 (18%)
Query: 1080 PPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFR-RKMGTEGSE 1138
PP PP P+ P+ PP LG +S P G G+ F GT +
Sbjct: 2193 PPTYPPYPSPTGAPA-QPPMLGASSRP--------------GAGQPGEFHTTPPGTPRHQ 2237
Query: 1139 PGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAG 1198
P P + P + +A+P G P P E S +A + ++ A
Sbjct: 2238 PSTPDPFL-KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE-SRKALEVKKEELGAS 2295
Query: 1199 PGSWKPPPPPQSTKPSFSAMRRAEATWHIA--EESAPNHSCQSPSPASQDGEEEKEGT-L 1255
S+ PP PS H+ E P+ +P + E + G L
Sbjct: 2296 SPSYGPPNLGFVDSPSSGT--------HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
Query: 1256 FPERTLPARNAKLQDPALAPWPP----------------KPVAVPRGRQPPQEPGVREEA 1299
P+ PA+ ALAP PP +P PR + PP E
Sbjct: 2348 RPQEPPPAQ-------ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 1300 EAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLE--PDR 1357
+ + P P +S Q Q + P P A T R QS D P R
Sbjct: 2401 RSLPSDPFSRVP----ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
Query: 1358 RRPPDP 1363
+ DP
Sbjct: 2457 PQSRDP 2462
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/261 (25%), Positives = 97/261 (37%), Gaps = 26/261 (9%)
Query: 1040 SEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPS 1099
S A LP L + +R L RP + S + PPPPPP +PP+P P
Sbjct: 141 SRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSA----PPPPPPGRRANAPPTPLP-- 194
Query: 1100 LGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQ-PRVHGVA 1158
+ ++ +P ++ E+ PG G + G P + P+P + P +A
Sbjct: 195 MHSSKAPAYNREKPLPPTPGQRLHPG-----REGPPAPPPVKPPPSPVNIRTGPSGQSLA 249
Query: 1159 LPGLERAKGWSFDGKREGPG-PDQEGSTQAWQKRRSSDDAGPGSWK--PPPPPQSTKPSF 1215
P + G GP P E + + Q+ S PG + PPPP S PS
Sbjct: 250 PPPPPYRQP---PGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSL 306
Query: 1216 SAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAP 1275
+ R A + P P ++G + P P R + P+
Sbjct: 307 LSNRPPPPARDPPSRGA---APPPPPPVIRNGARDA-----PPPPPPYRMHGSEPPSRGK 358
Query: 1276 WPPKPVAVPRGRQPPQEPGVR 1296
PP P P G PP P +R
Sbjct: 359 PPPPPSRTPAGPPPPPPPPLR 379
Score = 49.3 bits (116), Expect = 3e-05
Identities = 82/323 (25%), Positives = 114/323 (35%), Gaps = 56/323 (17%)
Query: 1079 LPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEE---SSLLPGFGGG------------ 1123
+PPPPPPPP PP P N P S +E+ +LL G
Sbjct: 3 IPPPPPPPP---GPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDR 59
Query: 1124 RGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKG-WSFDGKREGPGPD-- 1180
P + G+ G G + G A QP+ G+ G+ + + + DG G
Sbjct: 60 SAPILEKPKGSSG-----GYGSGGAALQPK-GGLFQGGVLKLRPVGAKDGSENLAGKPAL 113
Query: 1181 QEGSTQAWQKR--------RSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESA 1232
Q S++A R R DD P P+ +PS + R T +
Sbjct: 114 QIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTT----SSTG 169
Query: 1233 PNHSCQSPSPASQDGEEEKEGTLFPERT--LPARNAKLQDPALAPWPPKP-VAVPRGRQ- 1288
HS +P P T P + PA N + P PP P + GR+
Sbjct: 170 MKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNRE------KPLPPTPGQRLHPGREG 223
Query: 1289 PPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEV-QGPPDPGRRTAPLKPKRTRRA 1347
PP P V+ + G + L ++ P V GP P +AP P +R
Sbjct: 224 PPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELP---QRH 280
Query: 1348 QSCDKLEPDRRR---PPDPTGTS 1367
S + P R PP PT S
Sbjct: 281 NSLHRKTPGPVRGLAPPPPTSAS 303
Score = 47.0 bits (110), Expect = 1e-04
Identities = 83/338 (24%), Positives = 114/338 (33%), Gaps = 61/338 (18%)
Query: 915 KIRPVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQ 974
K++ V+ S +E G+ G G+ SG QP G+ +L G K +
Sbjct: 49 KLKKVTNINDRSAPILEKPKGSSG---GYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSE 105
Query: 975 T-QGRP--RPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRT 1031
G+P + P + P P A G Q++ ++R R L + S T
Sbjct: 106 NLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTT 165
Query: 1032 LRTVRPGLSEAPLPPLQKKRRRG-------------LFHFRRP-------RSFKGDRGPG 1071
T S AP PP +R ++ +P R G GP
Sbjct: 166 SSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPP 225
Query: 1072 SPTTGLLLPPP---------------PPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSL 1116
+P + PPP PPPPP ++ P P+ PS N S P+ +SL
Sbjct: 226 APPP--VKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSL 283
Query: 1117 ---LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGK 1173
PG G P T S P A+ P G A P +G
Sbjct: 284 HRKTPGPVRGLAP----PPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPV---IRNGA 336
Query: 1174 REGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST 1211
R+ P P R P KPPPPP T
Sbjct: 337 RDAPPPP--------PPYRMHGSEPPSRGKPPPPPSRT 366
Score = 43.9 bits (102), Expect = 0.001
Identities = 48/174 (27%), Positives = 61/174 (35%), Gaps = 40/174 (22%)
Query: 965 PTHGYKLRHQTQGRPRPPRTTPP--------GPGRPSM--PAPGTRQE----NGMATRLD 1010
PT G +L +G P PP PP GP S+ P P RQ NG ++ +
Sbjct: 211 PTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTN 270
Query: 1011 EGLEDFFSRRVLEESSSYPRTLRTVRPG---------LSEAPLPPLQKKRRRGLFHFRRP 1061
E + R + P +R + P LS P PP + RG P
Sbjct: 271 ESAPELPQRHNSLHRKT-PGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPP 329
Query: 1062 RSFKGD-------------RGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGN 1102
+ G P+ G PPPPP T PP P PP L N
Sbjct: 330 PVIRNGARDAPPPPPPYRMHGSEPPSRG---KPPPPPSRTPAGPPPPPPPPLRN 380
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 56.2 bits (134), Expect = 2e-07
Identities = 77/314 (24%), Positives = 106/314 (33%), Gaps = 78/314 (24%)
Query: 1026 SSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGL-------- 1077
SS PRT P +SE P+P L + R P S + P T L
Sbjct: 1043 SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1102
Query: 1078 ---LLPPPPPP--PPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKM 1132
PPPP P PPT+ +PP PP G SP + +E FG + P RK
Sbjct: 1103 LEPKRPPPPRPVAPPTRPAPPQRPPPPSGAR-SPAPTRKE-------FGAPKSPGTTRKD 1154
Query: 1133 GTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRR 1192
S+P P G A GPGP
Sbjct: 1155 NIGRSQP---SPQAGLA--------------------------GPGP------------- 1172
Query: 1193 SSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKE 1252
AG + +P PP++ S + + ES S S + +
Sbjct: 1173 ----AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQ 1228
Query: 1253 GTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG--RQPPQEPGVREEAEAGDAAPGVNK 1310
P+ +LP +LQ+P + P P + P+ PPQ P + + + P
Sbjct: 1229 AAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPP---PRSRSSHSLPS--- 1282
Query: 1311 PRLRLSSQQDQEEP 1324
SSQ QE+P
Sbjct: 1283 ---EASSQPQQEQP 1293
Score = 35.8 bits (81), Expect = 0.29
Identities = 48/193 (24%), Positives = 68/193 (35%), Gaps = 20/193 (10%)
Query: 1189 QKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGE 1248
Q + S +G G+ P S S + + I AP+ + PS S +
Sbjct: 1028 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1087
Query: 1249 EEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEP----GVREEAE---- 1300
+ P LP ++ P PP+PVA P PPQ P G R A
Sbjct: 1088 AQ------PATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKE 1141
Query: 1301 -AGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTA-PLKPKRT---RRAQSCDKLEP 1355
+PG + + + Q + + GP G TA P P R QS +
Sbjct: 1142 FGAPKSPGTTR-KDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASA 1200
Query: 1356 DRRRPPDPTGTSE 1368
R P + TSE
Sbjct: 1201 GRLTPESQSKTSE 1213
>gi|168986655 hypothetical protein LOC145497 [Homo sapiens]
Length = 488
Score = 56.2 bits (134), Expect = 2e-07
Identities = 63/222 (28%), Positives = 106/222 (47%), Gaps = 22/222 (9%)
Query: 429 NLSATKLPLE-------ALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGA-V 480
N++ TKL LE + +L++ L N +L ++++ S+ L GA+ + +
Sbjct: 132 NMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEMNI--SNNHLGLEGARIISDFFERNS 189
Query: 481 TCVGSLDLSDNGFDSDLLTLV-PALGKNKSLKHLFLGKN--FNVKAKTLEEILHKLVQLI 537
+ + SL+LS N F D L+ AL N +K L L N +V + L ++L V
Sbjct: 190 SSIWSLELSGNDFKEDSAALLCQALSTNYQIKKLDLSHNQFSDVGGEHLGQMLAINV--- 246
Query: 538 QEEDCSLQSLSVADSRLKLRTSI-LINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQIN 596
L SL ++ + R ++ L N L N L K+DLS NG + A L + L++N
Sbjct: 247 -----GLTSLDLSWNNFHTRGAVALCNGLRGNVTLTKLDLSMNGFGNEVALALGEVLRLN 301
Query: 597 SSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDIS 638
L + N+ G I++ LESN +LR + ++ I+
Sbjct: 302 RCLVYLDIGGNDIGNEGASKISKGLESNESLRVLKLFLNPIN 343
Score = 51.6 bits (122), Expect = 5e-06
Identities = 62/249 (24%), Positives = 96/249 (38%), Gaps = 43/249 (17%)
Query: 392 HLTYLNLARNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATKLPLEALRALLQGLSLNS 451
+L +N++ N R F++ SS ++L LS ++ L Q LS N
Sbjct: 162 YLQEMNISNNHLGLEGARIISDFFERNSSSIWSLE---LSGNDFKEDSAALLCQALSTNY 218
Query: 452 HLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGFDS-DLLTLVPALGKNKSL 510
+ L DLS + G + L + L + SLDLS N F + + L L N +L
Sbjct: 219 QIKKL--DLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLRGNVTL 276
Query: 511 KHLFLGKNF--NVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILINALGSN 568
L L N N A L E+L N
Sbjct: 277 TKLDLSMNGFGNEVALALGEVLRL-----------------------------------N 301
Query: 569 TCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESNHTLR 628
CL +D+ GN + + GA +SK L+ N SLR + N + G + + A++ N R
Sbjct: 302 RCLVYLDIGGNDIGNEGASKISKGLESNESLRVLKLFLNPINMDGAILLILAIKRNPKSR 361
Query: 629 FMSFPVSDI 637
+S++
Sbjct: 362 MEELDISNV 370
Score = 50.4 bits (119), Expect = 1e-05
Identities = 44/179 (24%), Positives = 84/179 (46%), Gaps = 9/179 (5%)
Query: 452 HLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGF-DSDLLTLVPALGKNKSL 510
++ + +++L+ L G +A+ L + V L+L DN + +L+LV L +N L
Sbjct: 104 NMEESYVNLNHHGLGPRGTKAIAIALVSNMAVTKLELEDNCIMEEGVLSLVEMLQENYYL 163
Query: 511 KHLFLGKN-FNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILI-NALGSN 568
+ + + N ++ + + + S+ SL ++ + K ++ L+ AL +N
Sbjct: 164 QEMNISNNHLGLEGARI------ISDFFERNSSSIWSLELSGNDFKEDSAALLCQALSTN 217
Query: 569 TCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESNHTL 627
+ K+DLS N D+G + L + L IN L ++ NN G + + L N TL
Sbjct: 218 YQIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLRGNVTL 276
Score = 45.1 bits (105), Expect = 5e-04
Identities = 57/217 (26%), Positives = 84/217 (38%), Gaps = 36/217 (16%)
Query: 188 NREFNLLDFSH--LESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSL 245
N E + ++ +H L R + AL N TKL +D + E + ++ L ++ L
Sbjct: 104 NMEESYVNLNHHGLGPRGTKAIAIALVSNMAVTKLELEDNCIMEEGVLSLVEMLQENYYL 163
Query: 246 EELVLDNAGLKTDFVQKLAGVFGENGSCV---------------------------LHAL 278
+E+ + N L + + ++ F N S + + L
Sbjct: 164 QEMNISNNHLGLEGARIISDFFERNSSSIWSLELSGNDFKEDSAALLCQALSTNYQIKKL 223
Query: 279 TLSHNPIEDKGFLSLSQQLLCFPSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRY 338
LSHN D G L Q+L GLT L L+ RG AL N +L
Sbjct: 224 DLSHNQFSDVGGEHLG-QMLAINVGLTSLDLSWNNFHTRGAVALCNGLRGN----VTLTK 278
Query: 339 LDLSKNPGLLATDEANALYSFLAQPNALVHLDLSGTD 375
LDLS N + A AL L LV+LD+ G D
Sbjct: 279 LDLSMNG--FGNEVALALGEVLRLNRCLVYLDIGGND 313
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 55.8 bits (133), Expect = 3e-07
Identities = 63/207 (30%), Positives = 78/207 (37%), Gaps = 40/207 (19%)
Query: 1079 LPPPPP----PPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPG-----FGGGRGPSFR 1129
LPPPPP PPP+Q PP P PP SP + +S+L G G G S R
Sbjct: 775 LPPPPPLAKFPPPSQPQPPPPPPP------SPASLLKSLASVLEGQKYCYRGTGAAVSTR 828
Query: 1130 -RKMGTEGSEPGEGGPA---PGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGST 1185
+ T PG A P T+ P G P + +S G GP
Sbjct: 829 PGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG---GP-------- 877
Query: 1186 QAW-QKRRSSDDAGPGSWKP--PPPPQSTKPSFSAMRRAEATWHIAEE--SAPNHSCQSP 1240
W ++RR+ ++ PG P PPPP S P+ S E E S P
Sbjct: 878 --WARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDP 935
Query: 1241 SPASQDGEEEKEGTLFPERTLPARNAK 1267
+ E GT ER LP AK
Sbjct: 936 ADPVDTAEPADSGT---ERLLPPAQAK 959
Score = 50.1 bits (118), Expect = 1e-05
Identities = 97/382 (25%), Positives = 126/382 (32%), Gaps = 77/382 (20%)
Query: 940 PPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPR------PPRTTPPGPGRPS 993
PPG G +P + S L G LR R R P TT P PS
Sbjct: 334 PPG-----PGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPS 388
Query: 994 MPA--PGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKR 1051
P PGT + ++ + GL R +E + P G P L+
Sbjct: 389 RPPGLPGTTTSSSSSSSSNTGL------RGVEPNPGIP--------GADHYQTPALEVSH 434
Query: 1052 RRGLFHFRRPRSFKGDRGP--GSP--TTGLLLPPPP--PPPPTQESPPSPDPPSLGNNSS 1105
H R S R P G+P T L LPP P PPPP P PP
Sbjct: 435 -----HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGP 489
Query: 1106 PCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERA 1165
C + E+ +L G EG P P P G P R
Sbjct: 490 ACRAAREDGEILEELFFGT----------------EGPPRPAPPPLPHREGFLGPPASRF 533
Query: 1166 KGWSFDGKREGPGPDQE-GSTQAWQKRRSSDDAGPGSWKPP--------PPPQSTKPSFS 1216
+ D P S+ + SS AGP S+ PP P P+ P+ +
Sbjct: 534 SVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQN 593
Query: 1217 AMRRAEATWHIAEESAPNHSC-QSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAP 1275
+A AP SC Q+ S + + E + FP + P + P
Sbjct: 594 PQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP-----------KTPEVGP 642
Query: 1276 WPPKPVAVPRGRQPPQEPGVRE 1297
PP P + + Q P PGV E
Sbjct: 643 GPP-PGPLSKAPQ-PVPPGVGE 662
Score = 41.6 bits (96), Expect = 0.005
Identities = 68/259 (26%), Positives = 85/259 (32%), Gaps = 33/259 (12%)
Query: 1065 KGDRGPGSPTTGLL----LPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGF 1120
K RG S TGL LPPPP PPP PP P PP G +SP + +
Sbjct: 228 KRRRGCNSEQTGLPPGLPLPPPPLPPP-PPPPPPPPPPLPGLATSPPFQLTKPGLWSTLH 286
Query: 1121 GGGRGPSFRRKMGTEGSEPGEGGPAP-------GTAQQP--RVHGVALPGL-ERAKGWSF 1170
G GP + E E P P TA P R+ A PG R G
Sbjct: 287 GDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAES 346
Query: 1171 DG---KREGPGPDQEGSTQAWQKRRSSDDAGPGSW---------KPPPPPQSTKPSFSAM 1218
G PG D S Q+ R P + +PP P +T S S+
Sbjct: 347 HGCLPATRPPGSDLRESRV--QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSS 404
Query: 1219 RRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALA---- 1274
+ + +PA + + G P A P L+
Sbjct: 405 SSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
Query: 1275 PWPPKPVAVPRGRQPPQEP 1293
P P P PR +PP P
Sbjct: 465 PSSPPPPPCPRLLRPPPPP 483
Score = 39.3 bits (90), Expect = 0.026
Identities = 97/390 (24%), Positives = 116/390 (29%), Gaps = 97/390 (24%)
Query: 939 IPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRH-----QT---QGRPRPPRTTPPGPG 990
+PP SG G EGLS G K R QT G P PP PP P
Sbjct: 209 VPPAALSGPSGE--------EGLSP----GGKRRRGCNSEQTGLPPGLPLPPPPLPPPPP 256
Query: 991 RPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKK 1050
P P P G+AT L L + P + PP +++
Sbjct: 257 PPPPPPPPL---PGLATSPPFQLTKPGLWSTLHGDAWGPE---------RKGSAPPERQE 304
Query: 1051 RRRGLFH-FRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP---PSPDPPSLGNNSSP 1106
+R L H + P PG P P P PP ES P+ PP S
Sbjct: 305 QRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESR 364
Query: 1107 CWSPEEESSL------------------LPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGT 1148
+SS+ LPG S G G EP G P
Sbjct: 365 VQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
Query: 1149 AQQPRV----HGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP 1204
Q P + HG P ++ P S GP S P
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATP--------------HLSLPPGPSSPPP 470
Query: 1205 PPPPQSTKP-------SFSAMRRAEATWHIAEE-----SAPNHSCQSPSPASQDGEEEKE 1252
PP P+ +P A R A I EE P P P +E
Sbjct: 471 PPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP-------HRE 523
Query: 1253 GTLFPERTLPARNAKL--QDPALAPWPPKP 1280
G L P PA + QD P PP P
Sbjct: 524 GFLGP----PASRFSVGTQDSHTPPTPPTP 549
Score = 31.2 bits (69), Expect = 7.1
Identities = 38/143 (26%), Positives = 45/143 (31%), Gaps = 34/143 (23%)
Query: 979 PRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTV--R 1036
P PP P P +P P P + L LE + Y T V R
Sbjct: 777 PPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEG--------QKYCYRGTGAAVSTR 828
Query: 1037 PGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP-PSP 1095
PG PLP Q PG P+ LPP P Q SP PS
Sbjct: 829 PG----PLPTTQYS-------------------PGPPSGATALPPTSAAPSAQGSPQPSA 865
Query: 1096 DPPSLGNNSSPCWSPEEESSLLP 1118
S + S W+ E + P
Sbjct: 866 SSSSQFSTSGGPWARERRAGEEP 888
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 54.3 bits (129), Expect = 8e-07
Identities = 104/425 (24%), Positives = 140/425 (32%), Gaps = 86/425 (20%)
Query: 925 GSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELP-THGYKLRHQTQGRPRPPR 983
G P D++ +G G PPG G P +G P G T G P PP
Sbjct: 107 GEPGDIKDIVGPKG-PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 165
Query: 984 TTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAP 1043
PPGP P P G MA DE + G+ + P
Sbjct: 166 --PPGP--PGPPGLGGNFAAQMAGGFDEKAGG-------------------AQLGVMQGP 202
Query: 1044 LPPLQKKRRRGLFHFRRPRSFKGDRG-PGSP-TTGLLLPPPPPPPPTQ--ESPPSPDPPS 1099
+ P+ + G P+ F+G+ G PG P +G + P PP PP + + + P
Sbjct: 203 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262
Query: 1100 LGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPA-PGTAQQPRVHGVA 1158
G P PG G +G R G +G++ G P G + P +G
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKG--HRGYPGLDGAKGEAGAPGVKGESGSPGENGS- 319
Query: 1159 LPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPP-QSTKPSFSA 1217
PG +G + R GP G+ A +D PG PP P + P F
Sbjct: 320 -PGPMGPRGLPGERGRTGPA----GAAGA-----RGNDGQPGPAGPPGPVGPAGGPGFPG 369
Query: 1218 MRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWP 1277
A+ E+ P + GE G+ PA A
Sbjct: 370 APGAKG------EAGPTGARGPEGAQGPRGEPGTPGS--------------PGPAGASGN 409
Query: 1278 PKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTA 1337
P +P + PG+ APG PR GPP P T
Sbjct: 410 PGTDGIPGAKGSAGAPGIA-------GAPGFPGPR---------------GPPGPQGATG 447
Query: 1338 PLKPK 1342
PL PK
Sbjct: 448 PLGPK 452
Score = 54.3 bits (129), Expect = 8e-07
Identities = 86/329 (26%), Positives = 110/329 (33%), Gaps = 32/329 (9%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPP------PPTQESPPSPDPPSLGNNSSPCWSPEEES 1114
P +G++G P+ LP PP P P Q P P L P E
Sbjct: 649 PAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG 708
Query: 1115 SLLPGFGGGRGPSFRRKMGTEGSE--PGEGGPA--PGTAQQPRVHGVALPGLERAKGWSF 1170
S PG G +GP R GT G++ G GPA PG P + G +PG A G +
Sbjct: 709 S--PGAQGLQGP--RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG--MPGERGAAGIA- 761
Query: 1171 DGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP--PPPPQSTKPSFSAMRRAEATWHIA 1228
GP D+ + + D G G P PP P +
Sbjct: 762 -----GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816
Query: 1229 EESAPNHSCQS--PSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG 1286
AP ++ P PA G +G P A + A AP P P P
Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQ--PGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874
Query: 1287 RQPPQEPGVR--EEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRT 1344
+ P G + A+ A G R+ P GPP P + P K R
Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP-KGARG 933
Query: 1345 RRAQSCDKLEPDRRRPPDPTG-TSEPGTD 1372
EP + P P G EPG D
Sbjct: 934 DSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962
Score = 44.7 bits (104), Expect = 6e-04
Identities = 85/303 (28%), Positives = 103/303 (33%), Gaps = 51/303 (16%)
Query: 1061 PRSFKGDRGP----GSPTTGLLLPPPPPP---------PPTQESPPSPDPPSLGNNSSPC 1107
P+ +GD GP G P GL P PP P E PP P L
Sbjct: 928 PKGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQRGIV 983
Query: 1108 WSPEEESSLLPGFGGGRGPSFRR-KMGTEGSEPGEGGPAPGTAQQPRVHGVA-LPGLERA 1165
P + GF G GPS K G G+ G+ GP PG P + G A PG E +
Sbjct: 984 GLPGQRGER--GFPGLPGPSGEPGKQGAPGAS-GDRGP-PGPVGPPGLTGPAGEPGREGS 1039
Query: 1166 KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAG-PGSWKPPPPPQSTKPSFSAMRRAEAT 1224
G +GP P ++G+ R + G PG+ PP P P+ R EA
Sbjct: 1040 PG------ADGP-PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1092
Query: 1225 WHIA---EESAPNHSCQSPS-PASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKP 1280
A Q P P GE + G ER L L P PP P
Sbjct: 1093 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG----ERGLKGHRGFTGLQGL-PGPPGP 1147
Query: 1281 V-----------AVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGP 1329
+ PRG P P ++ A G PR R P GP
Sbjct: 1148 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP 1207
Query: 1330 PDP 1332
P P
Sbjct: 1208 PGP 1210
Score = 41.2 bits (95), Expect = 0.007
Identities = 103/416 (24%), Positives = 144/416 (34%), Gaps = 58/416 (13%)
Query: 931 ESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPG 990
+ Q G G PPG GG P G+ E G + QG PR P PG
Sbjct: 347 DGQPGPAG-PPGPVGPAGG--PGFPGAPGAKGEAGPTGARGPEGAQG----PRGEPGTPG 399
Query: 991 RPSMP-APGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQK 1049
P A G +G+ G + + + +P P + PL P +
Sbjct: 400 SPGPAGASGNPGTDGIP-----GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 454
Query: 1050 KRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWS 1109
G+ F+ + KG+ GP P P P + +P +G P
Sbjct: 455 TGEPGIAGFKGEQGPKGEPGPAGPQGA-----PGPAGEEGKRGARGEPGGVG----PIGP 505
Query: 1110 PEEESSLLPGFGGGRG-PSFRRKMGTEGSEPGEGGPAPGTAQQPRVHG----VALPGLER 1164
P E G G RG P G +G+ PGE GP+ G A +G PGL
Sbjct: 506 PGER-----GAPGNRGFPGQDGLAGPKGA-PGERGPS-GLAGPKGANGDPGRPGEPGLPG 558
Query: 1165 AKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTK-----PSFSAMR 1219
A+G G+ GP + +D PG PP PQ + F +
Sbjct: 559 ARG--LTGRPGDAGPQGKVGPSG----APGEDGRPG----PPGPQGARGQPGVMGFPGPK 608
Query: 1220 RAEA-TWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPP 1278
A E+ P +P G++ + G P PA A + AP P
Sbjct: 609 GANGEPGKAGEKGLPG----APGLRGLPGKDGETGAAGPPG--PAGPAGERGEQGAPGPS 662
Query: 1279 KPVAVPRGRQPPQEPG-VREEAEAGDA-APGVNKPRLRLSSQQDQEEPEVQGPPDP 1332
+P PP E G ++ G+A APG+ PR ++ P QG P
Sbjct: 663 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718
Score = 36.2 bits (82), Expect = 0.22
Identities = 79/320 (24%), Positives = 94/320 (29%), Gaps = 66/320 (20%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP------------PSP----DPPSLGNNS 1104
P+ KG+ G G PP P P ++ P P P P N
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 161
Query: 1105 SPCWSPEEESSLLPGFGGG----RGPSFRRKMGTE--GSEPGEGGP-----APGTAQQPR 1153
P P PG GG F K G G G GP PG A P
Sbjct: 162 GPPGPPGPPGP--PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219
Query: 1154 VHGV-ALPGLERAKGWSFD-GKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST 1211
G PG G S G R PGP + + G + PP PQ
Sbjct: 220 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG-----EAGKPGKAGERGPPGPQGA 274
Query: 1212 K-----------------PSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
+ P + + ES SP P G + G
Sbjct: 275 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334
Query: 1255 LFPERTLPAR-NAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAP-GVNKPR 1312
P AR N PA PP PV G P PG + G+A P G P
Sbjct: 335 TGPAGAAGARGNDGQPGPA---GPPGPVGPAGGPGFPGAPGAK-----GEAGPTGARGPE 386
Query: 1313 LRLSSQQDQEEPEVQGPPDP 1332
+Q + EP G P P
Sbjct: 387 ---GAQGPRGEPGTPGSPGP 403
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 54.3 bits (129), Expect = 8e-07
Identities = 104/425 (24%), Positives = 140/425 (32%), Gaps = 86/425 (20%)
Query: 925 GSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELP-THGYKLRHQTQGRPRPPR 983
G P D++ +G G PPG G P +G P G T G P PP
Sbjct: 38 GEPGDIKDIVGPKG-PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 96
Query: 984 TTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAP 1043
PPGP P P G MA DE + G+ + P
Sbjct: 97 --PPGP--PGPPGLGGNFAAQMAGGFDEKAGG-------------------AQLGVMQGP 133
Query: 1044 LPPLQKKRRRGLFHFRRPRSFKGDRG-PGSP-TTGLLLPPPPPPPPTQ--ESPPSPDPPS 1099
+ P+ + G P+ F+G+ G PG P +G + P PP PP + + + P
Sbjct: 134 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 193
Query: 1100 LGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPA-PGTAQQPRVHGVA 1158
G P PG G +G R G +G++ G P G + P +G
Sbjct: 194 AGERGPPGPQGARGFPGTPGLPGVKG--HRGYPGLDGAKGEAGAPGVKGESGSPGENGS- 250
Query: 1159 LPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPP-QSTKPSFSA 1217
PG +G + R GP G+ A +D PG PP P + P F
Sbjct: 251 -PGPMGPRGLPGERGRTGPA----GAAGA-----RGNDGQPGPAGPPGPVGPAGGPGFPG 300
Query: 1218 MRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWP 1277
A+ E+ P + GE G+ PA A
Sbjct: 301 APGAKG------EAGPTGARGPEGAQGPRGEPGTPGS--------------PGPAGASGN 340
Query: 1278 PKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTA 1337
P +P + PG+ APG PR GPP P T
Sbjct: 341 PGTDGIPGAKGSAGAPGIA-------GAPGFPGPR---------------GPPGPQGATG 378
Query: 1338 PLKPK 1342
PL PK
Sbjct: 379 PLGPK 383
Score = 54.3 bits (129), Expect = 8e-07
Identities = 86/329 (26%), Positives = 110/329 (33%), Gaps = 32/329 (9%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPP------PPTQESPPSPDPPSLGNNSSPCWSPEEES 1114
P +G++G P+ LP PP P P Q P P L P E
Sbjct: 580 PAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG 639
Query: 1115 SLLPGFGGGRGPSFRRKMGTEGSE--PGEGGPA--PGTAQQPRVHGVALPGLERAKGWSF 1170
S PG G +GP R GT G++ G GPA PG P + G +PG A G +
Sbjct: 640 S--PGAQGLQGP--RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG--MPGERGAAGIA- 692
Query: 1171 DGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKP--PPPPQSTKPSFSAMRRAEATWHIA 1228
GP D+ + + D G G P PP P +
Sbjct: 693 -----GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747
Query: 1229 EESAPNHSCQS--PSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRG 1286
AP ++ P PA G +G P A + A AP P P P
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQ--PGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805
Query: 1287 RQPPQEPGVR--EEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRT 1344
+ P G + A+ A G R+ P GPP P + P K R
Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP-KGARG 864
Query: 1345 RRAQSCDKLEPDRRRPPDPTG-TSEPGTD 1372
EP + P P G EPG D
Sbjct: 865 DSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893
Score = 44.7 bits (104), Expect = 6e-04
Identities = 85/303 (28%), Positives = 103/303 (33%), Gaps = 51/303 (16%)
Query: 1061 PRSFKGDRGP----GSPTTGLLLPPPPPP---------PPTQESPPSPDPPSLGNNSSPC 1107
P+ +GD GP G P GL P PP P E PP P L
Sbjct: 859 PKGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQRGIV 914
Query: 1108 WSPEEESSLLPGFGGGRGPSFRR-KMGTEGSEPGEGGPAPGTAQQPRVHGVA-LPGLERA 1165
P + GF G GPS K G G+ G+ GP PG P + G A PG E +
Sbjct: 915 GLPGQRGER--GFPGLPGPSGEPGKQGAPGAS-GDRGP-PGPVGPPGLTGPAGEPGREGS 970
Query: 1166 KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAG-PGSWKPPPPPQSTKPSFSAMRRAEAT 1224
G +GP P ++G+ R + G PG+ PP P P+ R EA
Sbjct: 971 PG------ADGP-PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023
Query: 1225 WHIA---EESAPNHSCQSPS-PASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKP 1280
A Q P P GE + G ER L L P PP P
Sbjct: 1024 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG----ERGLKGHRGFTGLQGL-PGPPGP 1078
Query: 1281 V-----------AVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGP 1329
+ PRG P P ++ A G PR R P GP
Sbjct: 1079 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP 1138
Query: 1330 PDP 1332
P P
Sbjct: 1139 PGP 1141
Score = 41.2 bits (95), Expect = 0.007
Identities = 103/416 (24%), Positives = 144/416 (34%), Gaps = 58/416 (13%)
Query: 931 ESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPG 990
+ Q G G PPG GG P G+ E G + QG PR P PG
Sbjct: 278 DGQPGPAG-PPGPVGPAGG--PGFPGAPGAKGEAGPTGARGPEGAQG----PRGEPGTPG 330
Query: 991 RPSMP-APGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQK 1049
P A G +G+ G + + + +P P + PL P +
Sbjct: 331 SPGPAGASGNPGTDGIP-----GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385
Query: 1050 KRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWS 1109
G+ F+ + KG+ GP P P P + +P +G P
Sbjct: 386 TGEPGIAGFKGEQGPKGEPGPAGPQGA-----PGPAGEEGKRGARGEPGGVG----PIGP 436
Query: 1110 PEEESSLLPGFGGGRG-PSFRRKMGTEGSEPGEGGPAPGTAQQPRVHG----VALPGLER 1164
P E G G RG P G +G+ PGE GP+ G A +G PGL
Sbjct: 437 PGER-----GAPGNRGFPGQDGLAGPKGA-PGERGPS-GLAGPKGANGDPGRPGEPGLPG 489
Query: 1165 AKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTK-----PSFSAMR 1219
A+G G+ GP + +D PG PP PQ + F +
Sbjct: 490 ARG--LTGRPGDAGPQGKVGPSG----APGEDGRPG----PPGPQGARGQPGVMGFPGPK 539
Query: 1220 RAEA-TWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPP 1278
A E+ P +P G++ + G P PA A + AP P
Sbjct: 540 GANGEPGKAGEKGLPG----APGLRGLPGKDGETGAAGPPG--PAGPAGERGEQGAPGPS 593
Query: 1279 KPVAVPRGRQPPQEPG-VREEAEAGDA-APGVNKPRLRLSSQQDQEEPEVQGPPDP 1332
+P PP E G ++ G+A APG+ PR ++ P QG P
Sbjct: 594 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 649
Score = 36.2 bits (82), Expect = 0.22
Identities = 79/320 (24%), Positives = 94/320 (29%), Gaps = 66/320 (20%)
Query: 1061 PRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP------------PSP----DPPSLGNNS 1104
P+ KG+ G G PP P P ++ P P P P N
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 1105 SPCWSPEEESSLLPGFGGG----RGPSFRRKMGTE--GSEPGEGGP-----APGTAQQPR 1153
P P PG GG F K G G G GP PG A P
Sbjct: 93 GPPGPPGPPGP--PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150
Query: 1154 VHGV-ALPGLERAKGWSFD-GKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQST 1211
G PG G S G R PGP + + G + PP PQ
Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG-----EAGKPGKAGERGPPGPQGA 205
Query: 1212 K-----------------PSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGT 1254
+ P + + ES SP P G + G
Sbjct: 206 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265
Query: 1255 LFPERTLPAR-NAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAP-GVNKPR 1312
P AR N PA PP PV G P PG + G+A P G P
Sbjct: 266 TGPAGAAGARGNDGQPGPA---GPPGPVGPAGGPGFPGAPGAK-----GEAGPTGARGPE 317
Query: 1313 LRLSSQQDQEEPEVQGPPDP 1332
+Q + EP G P P
Sbjct: 318 ---GAQGPRGEPGTPGSPGP 334
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 54.3 bits (129), Expect = 8e-07
Identities = 89/406 (21%), Positives = 131/406 (32%), Gaps = 43/406 (10%)
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRT 1034
T P P T P P P PAP T +E T + S P T +
Sbjct: 258 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----------------TKSAPTTPKE 300
Query: 1035 VRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP----PPPPPPPTQE 1090
P + P P K+ P + K +PTT P P P P +
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTPKEPAPTAPKKP 356
Query: 1091 SPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG--EGGPAPGT 1148
+P +P P+ P + +E S P P+ + T EP AP T
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 1149 AQQPRVHGVALPGLERAKGWS-FDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPP 1207
++P P K + K+ P +E + ++ + P P P
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 1208 PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAK 1267
+T + + T E+ AP + + P+P + + E P T P A
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPT-TPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAP 532
Query: 1268 LQDPALAPWPPKPVAVPRGRQP----PQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEE 1323
A AP PK A ++P P+EP E P P +E
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP-------TTLKE 585
Query: 1324 PEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
P P P + + + +CDK P + PT EP
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631
Score = 50.1 bits (118), Expect = 1e-05
Identities = 89/399 (22%), Positives = 129/399 (32%), Gaps = 64/399 (16%)
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPGTRQENGMAT--RLDEGLEDFFSRRVLEESSSYPRTL 1032
T P P T P P P PAP T +E T +L + + E+ + P T
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTP 511
Query: 1033 RTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP 1092
+ P E P P ++ +PTT P P P +P
Sbjct: 512 EELAPTTPEEPTPTTPEE--------------------PAPTTPKAAAPNTPKEPAPTTP 551
Query: 1093 PSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQP 1152
P P+ +P +P+E + P G + + T +P AP T ++P
Sbjct: 552 KEP-APTTPKEPAPT-TPKETAPTTP--KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 607
Query: 1153 RVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTK 1212
P KG + +E P P +T + P + K P P K
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTPKE-PAP----TTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662
Query: 1213 PSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPA 1272
P+ +E AP + + P+ + D P T P A
Sbjct: 663 PA-------------PKELAPT-TTKGPTSTTSDK---------PAPTTPKETAPTTPKE 699
Query: 1273 LAPWPPKPVAVPRGRQPP------QEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEV 1326
AP PK A PP P +E +P + P L E
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759
Query: 1327 QGPPDPGRRT-APLKPKRTRRAQSCDKLEPDRRRPPDPT 1364
+ P P +T A KP+ T A+ E D R P+ T
Sbjct: 760 KEPGVPTTKTPAATKPEMTTTAKD-KTTERDLRTTPETT 797
Score = 45.4 bits (106), Expect = 4e-04
Identities = 90/415 (21%), Positives = 128/415 (30%), Gaps = 64/415 (15%)
Query: 965 PTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEE 1024
PT K T P P P P P PAP T++ +
Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK---------EPAPTAP 353
Query: 1025 SSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPP 1084
P T + P + P P K+ P + K +PTT P
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK-----SAPTT----TKEPA 404
Query: 1085 PPPTQESPPSPDPPSLGNNSSPC-WSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGG 1143
P T+ +P +P PS P +P+E + P ++ T E
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----------KKPAPTTPKE----- 449
Query: 1144 PAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWK 1203
PAP T ++P P K P +E + +K +
Sbjct: 450 PAPTTPKEPAPTTTKKPA-------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 502
Query: 1204 PPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTL--FPERTL 1261
P P +T + E T EE AP +P A+ + +E T P T
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 1262 PARNAKLQDPALAPWPPKPVAVPRGRQP----PQEPGVREEAEAGDAAP---GVNKPRLR 1314
P A AP PK A ++P P++P +E A P +KP
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Query: 1315 LSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
P+ P P + AP PK T P + P PT +P
Sbjct: 619 TPKGTAPTTPKEPAPTTP-KEPAPTTPKGT---------APTTLKEPAPTTPKKP 663
Score = 42.4 bits (98), Expect = 0.003
Identities = 70/309 (22%), Positives = 99/309 (32%), Gaps = 37/309 (11%)
Query: 1072 SPTTGLLLPPPPPPP-PTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRR 1130
+PTT P P P PT P+P P +P + E P+ +
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEP------------APTTTK 292
Query: 1131 KMGTEGSEPG---EGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQA 1187
T EP PAP T ++P P K + K P +E + A
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352
Query: 1188 WQKRRSSDDAGPGSWKPPPP-------PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSP 1240
+K + P P P P T P A ++ +E AP + +P
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 1241 SPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAE 1300
+ E T P T P A AP PK A P + P ++ A
Sbjct: 413 TTPK---EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAP 468
Query: 1301 AGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRP 1360
P P+ + + P P+ T P KP T + ++L P
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTT---PEKLAPTTPEKPAPT----TPEELAPTTPEE 521
Query: 1361 PDPTGTSEP 1369
P PT EP
Sbjct: 522 PTPTTPEEP 530
Score = 36.2 bits (82), Expect = 0.22
Identities = 48/238 (20%), Positives = 76/238 (31%), Gaps = 22/238 (9%)
Query: 1134 TEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRS 1193
T +E GPA T ++P P S K P + T + +
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPA-------STTPKEPTPTTIKSAPTTPKEPAPT 250
Query: 1194 SDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEG 1253
+ + P + K P P + +P+ + + T +E AP + +P+ +
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKE-------- 300
Query: 1254 TLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRL 1313
P T P + A AP PK ++P P +E A P P+
Sbjct: 301 ---PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTPKEPAPTAPKK 355
Query: 1314 RLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGT 1371
+ + P P P P A + K P + P PT T T
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 54.3 bits (129), Expect = 8e-07
Identities = 89/406 (21%), Positives = 131/406 (32%), Gaps = 43/406 (10%)
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRT 1034
T P P T P P P PAP T +E T + S P T +
Sbjct: 299 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----------------TKSAPTTPKE 341
Query: 1035 VRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLP----PPPPPPPTQE 1090
P + P P K+ P + K +PTT P P P P +
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK----EPAPTTKEPAPTTPKEPAPTAPKKP 397
Query: 1091 SPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPG--EGGPAPGT 1148
+P +P P+ P + +E S P P+ + T EP AP T
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 1149 AQQPRVHGVALPGLERAKGWS-FDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPP 1207
++P P K + K+ P +E + ++ + P P P
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 1208 PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAK 1267
+T + + T E+ AP + + P+P + + E P T P A
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPT-TPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAP 573
Query: 1268 LQDPALAPWPPKPVAVPRGRQP----PQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEE 1323
A AP PK A ++P P+EP E P P +E
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP-------TTLKE 626
Query: 1324 PEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
P P P + + + +CDK P + PT EP
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672
Score = 50.1 bits (118), Expect = 1e-05
Identities = 89/399 (22%), Positives = 129/399 (32%), Gaps = 64/399 (16%)
Query: 975 TQGRPRPPRTTPPGPGRPSMPAPGTRQENGMAT--RLDEGLEDFFSRRVLEESSSYPRTL 1032
T P P T P P P PAP T +E T +L + + E+ + P T
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTP 552
Query: 1033 RTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESP 1092
+ P E P P ++ +PTT P P P +P
Sbjct: 553 EELAPTTPEEPTPTTPEE--------------------PAPTTPKAAAPNTPKEPAPTTP 592
Query: 1093 PSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQP 1152
P P+ +P +P+E + P G + + T +P AP T ++P
Sbjct: 593 KEP-APTTPKEPAPT-TPKETAPTTP--KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 648
Query: 1153 RVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTK 1212
P KG + +E P P +T + P + K P P K
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTPKE-PAP----TTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703
Query: 1213 PSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPA 1272
P+ +E AP + + P+ + D P T P A
Sbjct: 704 PA-------------PKELAPT-TTKGPTSTTSDK---------PAPTTPKETAPTTPKE 740
Query: 1273 LAPWPPKPVAVPRGRQPP------QEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEV 1326
AP PK A PP P +E +P + P L E
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800
Query: 1327 QGPPDPGRRT-APLKPKRTRRAQSCDKLEPDRRRPPDPT 1364
+ P P +T A KP+ T A+ E D R P+ T
Sbjct: 801 KEPGVPTTKTPAATKPEMTTTAKD-KTTERDLRTTPETT 838
Score = 45.4 bits (106), Expect = 4e-04
Identities = 90/415 (21%), Positives = 128/415 (30%), Gaps = 64/415 (15%)
Query: 965 PTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEE 1024
PT K T P P P P P PAP T++ +
Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK---------EPAPTAP 394
Query: 1025 SSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPP 1084
P T + P + P P K+ P + K +PTT P
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK-----SAPTT----TKEPA 445
Query: 1085 PPPTQESPPSPDPPSLGNNSSPC-WSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGG 1143
P T+ +P +P PS P +P+E + P ++ T E
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----------KKPAPTTPKE----- 490
Query: 1144 PAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWK 1203
PAP T ++P P K P +E + +K +
Sbjct: 491 PAPTTPKEPAPTTTKKPA-------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 543
Query: 1204 PPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTL--FPERTL 1261
P P +T + E T EE AP +P A+ + +E T P T
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 1262 PARNAKLQDPALAPWPPKPVAVPRGRQP----PQEPGVREEAEAGDAAP---GVNKPRLR 1314
P A AP PK A ++P P++P +E A P +KP
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Query: 1315 LSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEP 1369
P+ P P + AP PK T P + P PT +P
Sbjct: 660 TPKGTAPTTPKEPAPTTP-KEPAPTTPKGT---------APTTLKEPAPTTPKKP 704
Score = 42.4 bits (98), Expect = 0.003
Identities = 70/309 (22%), Positives = 99/309 (32%), Gaps = 37/309 (11%)
Query: 1072 SPTTGLLLPPPPPPP-PTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRR 1130
+PTT P P P PT P+P P +P + E P+ +
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEP------------APTTTK 333
Query: 1131 KMGTEGSEPG---EGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQA 1187
T EP PAP T ++P P K + K P +E + A
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393
Query: 1188 WQKRRSSDDAGPGSWKPPPP-------PQSTKPSFSAMRRAEATWHIAEESAPNHSCQSP 1240
+K + P P P P T P A ++ +E AP + +P
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 1241 SPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAE 1300
+ E T P T P A AP PK A P + P ++ A
Sbjct: 454 TTPK---EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAP 509
Query: 1301 AGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRP 1360
P P+ + + P P+ T P KP T + ++L P
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTT---PEKLAPTTPEKPAPT----TPEELAPTTPEE 562
Query: 1361 PDPTGTSEP 1369
P PT EP
Sbjct: 563 PTPTTPEEP 571
Score = 36.2 bits (82), Expect = 0.22
Identities = 48/238 (20%), Positives = 76/238 (31%), Gaps = 22/238 (9%)
Query: 1134 TEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRS 1193
T +E GPA T ++P P S K P + T + +
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPA-------STTPKEPTPTTIKSAPTTPKEPAPT 291
Query: 1194 SDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEG 1253
+ + P + K P P + +P+ + + T +E AP + +P+ +
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKE-------- 341
Query: 1254 TLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRL 1313
P T P + A AP PK ++P P +E A P P+
Sbjct: 342 ---PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTPKEPAPTAPKK 396
Query: 1314 RLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGT 1371
+ + P P P P A + K P + P PT T T
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,669,420
Number of Sequences: 37866
Number of extensions: 3830702
Number of successful extensions: 40122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 318
Number of HSP's successfully gapped in prelim test: 1382
Number of HSP's that attempted gapping in prelim test: 21239
Number of HSP's gapped (non-prelim): 11250
length of query: 1372
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1257
effective length of database: 13,892,928
effective search space: 17463410496
effective search space used: 17463410496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.