Search of human proteins with 156616290

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156616290 collagen type VI alpha 6 [Homo sapiens]
         (2263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156616290 collagen type VI alpha 6 [Homo sapiens]                 4511   0.0  
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]             2277   0.0  
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...  1144   0.0  
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...  1144   0.0  
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...  1116   0.0  
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ...   436   e-121
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ...   363   1e-99
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...   287   7e-77
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...   286   2e-76
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...   286   2e-76
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]       283   1e-75
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   282   3e-75
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   282   3e-75
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     280   1e-74
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     275   4e-73
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      275   4e-73
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              275   4e-73
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   270   1e-71
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   270   1e-71
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   270   1e-71
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     266   1e-70
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               266   1e-70
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   265   3e-70
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   264   6e-70
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   264   6e-70
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   264   6e-70
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       263   1e-69
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   263   2e-69
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      262   3e-69
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         261   6e-69

>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 4511 bits (11700), Expect = 0.0
 Identities = 2263/2263 (100%), Positives = 2263/2263 (100%)

Query: 1    MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIE 60
            MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIE
Sbjct: 1    MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIE 60

Query: 61   ADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFS 120
            ADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFS
Sbjct: 61   ADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFS 120

Query: 121  APANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS 180
            APANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS
Sbjct: 121  APANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS 180

Query: 181  QFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSING 240
            QFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSING
Sbjct: 181  QFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSING 240

Query: 241  SEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLS 300
            SEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLS
Sbjct: 241  SEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLS 300

Query: 301  PRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGV 360
            PRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGV
Sbjct: 301  PRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGV 360

Query: 361  TIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSE 420
            TIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSE
Sbjct: 361  TIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSE 420

Query: 421  RTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQY 480
            RTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQY
Sbjct: 421  RTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQY 480

Query: 481  ADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCH 540
            ADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCH
Sbjct: 481  ADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCH 540

Query: 541  LVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALK 600
            LVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALK
Sbjct: 541  LVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALK 600

Query: 601  DIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQ 660
            DIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQ
Sbjct: 601  DIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQ 660

Query: 661  IGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARP 720
            IGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARP
Sbjct: 661  IGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARP 720

Query: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780
            NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN
Sbjct: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780

Query: 781  FDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKAD 840
            FDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKAD
Sbjct: 781  FDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKAD 840

Query: 841  VGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFT 900
            VGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFT
Sbjct: 841  VGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFT 900

Query: 901  EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMA 960
            EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMA
Sbjct: 901  EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMA 960

Query: 961  GSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMK 1020
            GSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMK
Sbjct: 961  GSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMK 1020

Query: 1021 EFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIG 1080
            EFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIG
Sbjct: 1021 EFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIG 1080

Query: 1081 AALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDV 1140
            AALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDV
Sbjct: 1081 AALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDV 1140

Query: 1141 DDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKG 1200
            DDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKG
Sbjct: 1141 DDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKG 1200

Query: 1201 QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSEN 1260
            QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSEN
Sbjct: 1201 QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSEN 1260

Query: 1261 ILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDEL 1320
            ILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDEL
Sbjct: 1261 ILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDEL 1320

Query: 1321 RKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAE 1380
            RKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAE
Sbjct: 1321 RKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAE 1380

Query: 1381 RTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG 1440
            RTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG
Sbjct: 1381 RTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG 1440

Query: 1441 CYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPG 1500
            CYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPG
Sbjct: 1441 CYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPG 1500

Query: 1501 DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT 1560
            DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT
Sbjct: 1501 DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT 1560

Query: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL 1620
            GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL
Sbjct: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL 1620

Query: 1621 GSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIG 1680
            GSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIG
Sbjct: 1621 GSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIG 1680

Query: 1681 DPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRD 1740
            DPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRD
Sbjct: 1681 DPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRD 1740

Query: 1741 RSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHI 1800
            RSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHI
Sbjct: 1741 RSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHI 1800

Query: 1801 AILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPG 1860
            AILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPG
Sbjct: 1801 AILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPG 1860

Query: 1861 AHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV 1920
            AHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV
Sbjct: 1861 AHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV 1920

Query: 1921 IVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAE 1980
            IVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAE
Sbjct: 1921 IVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAE 1980

Query: 1981 FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS 2040
            FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS
Sbjct: 1981 FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS 2040

Query: 2041 KRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEI 2100
            KRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEI
Sbjct: 2041 KRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEI 2100

Query: 2101 LKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVK 2160
            LKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVK
Sbjct: 2101 LKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVK 2160

Query: 2161 SFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFF 2220
            SFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFF
Sbjct: 2161 SFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFF 2220

Query: 2221 QDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD 2263
            QDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD
Sbjct: 2221 QDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD 2263


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 2277 bits (5900), Expect = 0.0
 Identities = 1188/2194 (54%), Positives = 1559/2194 (71%), Gaps = 24/2194 (1%)

Query: 2    MLLILFLVIICSHISVNQDSGPE--YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPI 59
            +LLI+F++II +    +Q  GP   YADVVFLVDSSD LG KSFPFVK FI KMI+SLPI
Sbjct: 3    ILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPI 62

Query: 60   EADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYF 119
            EA+KYRVALAQYSD+ HSEFHLSTFKGRSPMLNHL+KNF FIGGSLQIGKALQEAHRTYF
Sbjct: 63   EANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYF 122

Query: 120  SAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179
            SAP NGRD+KQFPPILVVLAS+ESED VEEASKAL+KDGVKIISVGVQKASEENLKAMAT
Sbjct: 123  SAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMAT 182

Query: 180  SQFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVD-DIFVE---ACQGPSMADVVFLLD 235
            S FHFNLRT+RDLS FSQNMT IIKDV KYKEGAVD D+ V    +CQ  S+AD+VFL+D
Sbjct: 183  SHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVD 242

Query: 236  MSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQH 295
             S+ G+  N  +L+ FLE   S++D+KENCMR+GL++YSN  K I+ L     +SE  Q 
Sbjct: 243  ESL-GTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQ 301

Query: 296  IQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNL 355
            I+NLS + GK+ TGAAI ++R++ FS   GSR+ QGVPQIAVLVTHR S+D V  AA+NL
Sbjct: 302  IKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNL 361

Query: 356  RREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTV 415
            R E V +F L I+GA++TQLE+I S+P EQ +S LK++ADL  ++  FLKKL+N+I   +
Sbjct: 362  RLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQI 421

Query: 416  SVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRV 475
            S ++E+    K+GCVDT+EADI+ LIDGS S Q   F ++K F+ EV  MF+I P KVRV
Sbjct: 422  STYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRV 481

Query: 476  GAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGN 535
            G VQY+D  ++EF I  YSN  DL KAI NI+Q+ G T TG AL++ L +++   K R +
Sbjct: 482  GVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMS 541

Query: 536  KVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHD 595
            KVPC+L+VLT+GMS D ++EPA RLR E I V+A+GI  AN+ +L+EIAG+E+RV +  +
Sbjct: 542  KVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQN 601

Query: 596  FDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIG 655
            FDALK I+N+VV+EIC E+ C++MKADIMFLVDSS SIG ENF KMK FMKNL++K QIG
Sbjct: 602  FDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIG 661

Query: 656  PDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPT 715
             D+ QIGVVQFSD  KEEFQLNR+ +Q +IS+AID+M+ I + TLTG AL+FV QYF+ +
Sbjct: 662  ADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721

Query: 716  KGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMV 775
            KGAR   +KFLILITDG AQD V++PA +LR + V I+SVGV+ +N +QLEEISG   +V
Sbjct: 722  KGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLV 781

Query: 776  FYVENFDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGL 835
            F+VENFD L+ +E  L+F +C+   +CKRI +LDVVFV+D SGSI     + M +  I L
Sbjct: 782  FHVENFDHLKALERKLIFRVCA-LHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840

Query: 836  VKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS 895
            VKKADVG+++V+FGALKY+D P +LFYL+ +  +  +I  L+  +  GG+TYTA+AL  +
Sbjct: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA 900

Query: 896  DHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955
            + +FTE  GSR+ + V Q+LIVITDGESHD D+LN TA  LR+KGI + AVG+  AN  E
Sbjct: 901  NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE 960

Query: 956  LLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPND 1015
            L  MAG+ +   +V+ F  LK +F+ V   +C  +   C + + D++FL DGS  +  +D
Sbjct: 961  LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD 1020

Query: 1016 FKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFG 1075
            F  M  FL+ ++ +FD+   R++IG AQF   Y     L   + + +   QI+N+ +  G
Sbjct: 1021 FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG 1080

Query: 1076 NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSV 1135
               I  AL++V + F    G R N G PQ L+V+T G  + +VA A + L+  GI +  +
Sbjct: 1081 FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL 1140

Query: 1136 GIGDVDDQQLIQITGTAEKKLTVHNFDELKKVN--KRIVRNICTTAGESNCFVDVVVGFD 1193
            GIGDV  + L+ ITG +EK +T  +FD+LK V+  KRI+R IC + G++NCF+D+VVGFD
Sbjct: 1141 GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD 1200

Query: 1194 VSTQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPK 1253
            +ST  +GQ L +G P +E+YL  IL  ISS+ GVSC  GTE QVS+AF+V N+ + +  K
Sbjct: 1201 ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKV-NSDQGFPAK 1259

Query: 1254 FEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVE-K 1312
            F+IY + + +SL  + V GP+ LNA  L SLWDTF++KSA+RG+V+L+FSDGL  +    
Sbjct: 1260 FQIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIM 1319

Query: 1313 LEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLS 1372
            LE +SD LR+ GL+AL+ V+L+  A      +    EFGK F+YRT L+IGMRELG +LS
Sbjct: 1320 LENQSDRLREAGLDALLVVSLNTTAHH----EFSSFEFGKRFDYRTHLTIGMRELGKKLS 1375

Query: 1373 KQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGP 1432
            + L N+AERTCCC FCKC G  G  G  G    +G  G KGS G+ GE+G  G RG  GP
Sbjct: 1376 QYLGNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGP 1435

Query: 1433 VGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGS 1492
             G++G  GC G  G KG +G +G +G  G++GIDGL+GE+G +G PG KGEKGD GSQGS
Sbjct: 1436 QGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS 1495

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTA 1552
            PG RG PG  G KG  GDPG PG +++I+G  G KGE+GRQGR G  G  G+P SR    
Sbjct: 1496 PGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRG 1555

Query: 1553 AHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGG 1612
              G+RG  G  G  G PGP G  G+ GL+GPQG +G  G KGEKG  G KGPQG PG  G
Sbjct: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMG 1615

Query: 1613 EAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGE 1672
              G+ GR G  G KGEPG  G+ G VG  G RG QG+ G PGYG +GRKG KG  GFPG+
Sbjct: 1616 AKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGD 1675

Query: 1673 SGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTC 1732
            +G KG+IG+PG PG  G KG RG  ++ GL GE GS G PGPPG++G+KG  G   +S C
Sbjct: 1676 AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQC 1735

Query: 1733 ELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVREN 1792
            +LI+++R+ SP    K +CP +PTELVFALD+S DVTE+ F + ++++  +V D+ +REN
Sbjct: 1736 DLIRFLREHSP--CWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIREN 1793

Query: 1793 SCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRN 1852
            +CPVGA +A++SYNS   +L+R+SD  +K QLL+++  I Y+ ++  R++G AMRF++RN
Sbjct: 1794 NCPVGARVAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRN 1853

Query: 1853 VFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAI 1912
            VFKRT  GA+ R++A FFS+GQ+A   SI TA MEF AL+I P V  F     +  AF  
Sbjct: 1854 VFKRTYAGANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFL-EAFGF 1912

Query: 1913 DDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDA 1972
            D+TGTFQVI VP   +    LERL+RC  CYD C P+A C +    P  SYMD  FL+D 
Sbjct: 1913 DNTGTFQVIPVPPNGEN-QTLERLRRCALCYDKCFPNA-CIREAFLPEDSYMDVVFLIDN 1970

Query: 1973 SRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAE 2032
            SRN+   EF+ ++A + +++D+F I  +P  S +GDR+ALLS++P +     +   V+ E
Sbjct: 1971 SRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWE-SSRRKMGTVKTE 2029

Query: 2033 FNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGE 2092
            F+  TY ++ LMK H+  S +QLNG+A IG AL WT +N+F  TP LR++KVIFV+SAGE
Sbjct: 2030 FDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGE 2089

Query: 2093 TSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDH 2152
             ++   E +K  +LRAKCQGY +FV SLG    D ++E+LAS+PLD HL+QLGRIHKPD 
Sbjct: 2090 -NYERKEFVKMMALRAKCQGYVIFVISLGSTRKD-DMEELASYPLDQHLIQLGRIHKPDL 2147

Query: 2153 SYGVKFVKSFINSIRRAINKYPPINLKIKCNRLN 2186
            +Y  KF+K F+ S+RR  N+YPP  L+  C  +N
Sbjct: 2148 NYIAKFLKPFLYSVRRGFNQYPPPMLEDACRLIN 2181



 Score =  303 bits (776), Expect = 1e-81
 Identities = 145/245 (59%), Positives = 191/245 (77%), Gaps = 1/245 (0%)

Query: 1947 KPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVT 2006
            +PD + +       + YMD AFL+DAS+ +GS EF++++AF+ ++LD+F I P P TS  
Sbjct: 2273 EPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTL 2332

Query: 2007 GDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQ 2066
            GDRVA+LS++PP ++PNT++ PV  EF+L TY S   MK H+ +S +QLNGD FIGHALQ
Sbjct: 2333 GDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDS-QQLNGDVFIGHALQ 2391

Query: 2067 WTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDD 2126
            WT+DNVF+ TPNLR+NKVIFVISAGET+ LD ++L+  SLRAKCQGY++FVFS GP  +D
Sbjct: 2392 WTIDNVFVGTPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHND 2451

Query: 2127 KELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCNRLN 2186
            KELE+LASHPLDHHLVQLGR HKPD +Y +KFVK F++ IRRAINKYP  ++K  C  + 
Sbjct: 2452 KELEELASHPLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMT 2511

Query: 2187 SIDPK 2191
            S +P+
Sbjct: 2512 SPNPE 2516



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 48/221 (21%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query: 229  DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM------RVGLVAYSNETKVINS 282
            DV FL+D S     + F  +K F+   +    I    +      RV +++YS    + N+
Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350

Query: 283  LSMGI----------NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGV 332
                +          +  ++  H+Q+     G  + G A++     VF      RKN+ +
Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410

Query: 333  PQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGI-EGASDTQLEKIASHPAEQYVSKL- 390
              I+   T+   +D +   ++  + +G +IF        +D +LE++ASHP + ++ +L 
Sbjct: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQLG 2470

Query: 391  KTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVD 431
            +T      +   F+K   + I   ++ +   TE +K+ CV+
Sbjct: 2471 RTHKPDWNYIIKFVKPFVHLIRRAINKYP--TEDMKATCVN 2509



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 50/180 (27%), Positives = 77/180 (42%), Gaps = 20/180 (11%)

Query: 25   YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKY------RVALAQYSD----- 73
            Y DV FL+D+S R+GS  F  VK FIT ++    I           RVA+  YS      
Sbjct: 2289 YMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMP 2348

Query: 74   -----KLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDK 128
                  ++ EF L T+     M +HL+ +   + G + IG ALQ      F    N R  
Sbjct: 2349 NTEECPVYLEFDLVTYNSIHQMKHHLQDS-QQLNGDVFIGHALQWTIDNVFVGTPNLRKN 2407

Query: 129  KQFPPILVVLASSESEDNVEEASKALRKDG--VKIISVGVQKASEENLKAMATSQFHFNL 186
            K    I     +S  +D +   S   +  G  + + S G  K +++ L+ +A+     +L
Sbjct: 2408 KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFG-PKHNDKELEELASHPLDHHL 2466



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 50/190 (26%), Positives = 89/190 (46%), Gaps = 29/190 (15%)

Query: 420  ERTETLKSGCVDTEE--ADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKV---- 473
            E   T + G V  +E   D+  LID S    + +F E+K F++ V+  F+IAP  +    
Sbjct: 2273 EPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTL 2332

Query: 474  --RVGAVQYADSW----------DLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNF 521
              RV  + Y+              LEF++  Y++   +   +++ +Q+ G+   G AL +
Sbjct: 2333 GDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQW 2392

Query: 522  TL-SLLQKAKKQRGNKVPCHLVVL----TNGMSKDSILEPANRLREE--HIRVYAIGIKE 574
            T+ ++       R NKV   + V+    TN + KD +   + R + +   I V++ G K 
Sbjct: 2393 TIDNVFVGTPNLRKNKV---IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKH 2449

Query: 575  ANQTQLREIA 584
             N  +L E+A
Sbjct: 2450 -NDKELEELA 2458



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 42/181 (23%), Positives = 81/181 (44%), Gaps = 30/181 (16%)

Query: 617  KEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRV------QIGVVQFSD-- 668
            +E   D+ FL+D+S  +G + F ++K F+ +++    I P  +      ++ V+ +S   
Sbjct: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345

Query: 669  --INKE------EFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSF-VSQYFSPTKGAR 719
               N E      EF L  + S   + + +     +      G AL + +   F  T   R
Sbjct: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405

Query: 720  PNIRKFLILITDGEA----QDIVKEPAVVLRQEGVIIYSVGVFG----SNVTQLEEISGR 771
             N  K + +I+ GE     +D+++  ++  + +G   YS+ VF      N  +LEE++  
Sbjct: 2406 KN--KVIFVISAGETNSLDKDVLRNVSLRAKCQG---YSIFVFSFGPKHNDKELEELASH 2460

Query: 772  P 772
            P
Sbjct: 2461 P 2461



 Score = 38.9 bits (89), Expect = 0.058
 Identities = 36/161 (22%), Positives = 76/161 (47%), Gaps = 25/161 (15%)

Query: 999  VDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRV------RIGAAQFSDT-YHP- 1050
            +D+ FL+D S  +  ++FK++K F+ SV+  F ++   +      R+    +S   Y P 
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349

Query: 1051 --------EFPLGTFIGEKEISFQIENIKQIFGNTHIGAALR-EVEHYFRPDMGSRINTG 1101
                    EF L T+    ++   +++ +Q+ G+  IG AL+  +++ F      R N  
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKN-- 2407

Query: 1102 TPQVLLVLTDGQS----QDEVAQAAEALRHRGIDIYSVGIG 1138
              +V+ V++ G++    +D +   +   + +G  I+    G
Sbjct: 2408 --KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFG 2446



 Score = 37.4 bits (85), Expect = 0.17
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 21/138 (15%)

Query: 808  LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQV------RFGALKYA------D 855
            +DV F+ID+S  +  DE+  +K F+  ++    +    +      R   L Y+      +
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349

Query: 856  DPEVLFYLD----DFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNKG 910
              E   YL+     + +  ++   LQ+ Q + G  +   AL ++ D++F      R NK 
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNK- 2408

Query: 911  VPQVLIVITDGESHDADK 928
               V+ VI+ GE++  DK
Sbjct: 2409 ---VIFVISAGETNSLDK 2423


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 1144 bits (2960), Expect = 0.0
 Identities = 730/2191 (33%), Positives = 1148/2191 (52%), Gaps = 116/2191 (5%)

Query: 27   DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
            D++FL+D S  +G  +FP+V+ F+  +++SL I  D  RV L Q+SD   +EF L+T++ 
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492

Query: 87   RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
            +S +L HLR+     G  L  G AL   +  +F+     R ++  P +L++L + +SED+
Sbjct: 493  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 552

Query: 147  VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206
              +A+ AL + G+    VG  +A++  L+ +A +     L  + D S        +I+ +
Sbjct: 553  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQPL 610

Query: 207  IKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM 266
              Y  G V++  V   Q  S  D++FL D S N   + F  ++ FL + +  L++K    
Sbjct: 611  TTYVSGGVEE--VPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGT 667

Query: 267  RVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARNG 325
            R+ +  YS++ KV +      +K E+L  ++ +  +TGKA   G A+   ++ +F    G
Sbjct: 668  RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 727

Query: 326  SRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQ 385
            SR   GV Q  VL+    S D V   A NL++ GV  F    + A   +LE+I   PA  
Sbjct: 728  SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 787

Query: 386  YVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444
              ++ L    DL       LK + N     VS                 E D+  L+DGS
Sbjct: 788  LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDGS 831

Query: 445  GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504
               ++  F  +K F+  VV   ++   +VRV  VQY+D    EF +N Y NKQD+  A+ 
Sbjct: 832  EGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 890

Query: 505  NIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561
             +  +GG T NTGAAL F L   L+  A  +    VP  L+VLT   S D +  P+  ++
Sbjct: 891  QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVK 950

Query: 562  EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM-- 619
                    IGI  A+ T+++ I+        +  F  L  ++ QV+ E  T+   +E+  
Sbjct: 951  RGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELSR 1009

Query: 620  ---------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVV 664
                           K D++FL+D S S GPE F  ++T ++ LV    +G D  ++ V+
Sbjct: 1010 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVI 1068

Query: 665  QFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLT-GSALSFVSQ-YFSPTKGAR--P 720
            QFSD  K EF LN   S+ ++ NA+ ++   G   +  G+AL +VS+  F    G+R   
Sbjct: 1069 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1128

Query: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780
             + +FL+LI+ G++ D V +PAV L+Q GV  +++    ++  +L +IS  PE VF V  
Sbjct: 1129 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIAR-NADQEELVKISLSPEYVFSVST 1187

Query: 781  FDILQRIEDDLVFGICS-PREECKRI-------------EVLDVVFVIDSSGSIDYDEYN 826
            F  L  +E  L+  I +   E+ +++             +  D+VF+IDSS  +  D + 
Sbjct: 1188 FRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFA 1247

Query: 827  IMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST 886
             ++DF+  +V++ ++G ++VR G +++++D    FYL  + ++  V+  ++  +  GGS 
Sbjct: 1248 HIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSP 1307

Query: 887  Y-TAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVL 944
              T +AL F + ++F ++ GSR+  GVPQ L+++  G+S D   ++  A+ +R  GI+ L
Sbjct: 1308 LNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSGIVSL 1365

Query: 945  AVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDC---------- 994
             VG    +  EL  +       F V  F  L  I   +  S   S+              
Sbjct: 1366 GVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPS 1425

Query: 995  --EIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEF 1052
              E  K D+VFL+DGS + + + F+++  F++ +V       + +++G  Q++     EF
Sbjct: 1426 RPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEF 1485

Query: 1053 PLGTFIGEKEISFQIENIKQIFG---NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVL 1109
             L  F  +++I   I  +    G   NT +G     V H F P+ GSR++   PQ+  V+
Sbjct: 1486 FLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH-FVPEAGSRLDQRVPQIAFVI 1544

Query: 1110 TDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169
            T G+S ++    + AL  RG+ +++VG+ ++D +++ +I   +     V N  EL ++++
Sbjct: 1545 TGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSE 1604

Query: 1170 RIVRNI--------C--TTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILR 1219
            +++  +        C   T     C +DV++GFD S   + Q +   Q   E+ +  IL 
Sbjct: 1605 QVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKVDAILN 1661

Query: 1220 AISSLNGVSCEVGTETQVSVAFQV---TNAMEKYSPKFEIYSENILNSLKDITVKGPSLL 1276
             IS ++ VSC  G    V V+      +  +E +   F+ Y   +L   +++  + P +L
Sbjct: 1662 RISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD--FDEYQPEMLEKFRNMRSQHPYVL 1719

Query: 1277 NANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGP 1336
              + L    + F+  S    KVV+ F+DG D D+  L + S+ LR+EG+ ALI V L+  
Sbjct: 1720 TEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERV 1779

Query: 1337 ADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGT 1396
             +   L  L ++EFG+GF Y   L + + +L   L++QL N+AE+ CC + CKC G  G 
Sbjct: 1780 VN---LERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGD 1836

Query: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
             G  G  G +G PG  G  GY G+EG  GERG PG  G QG +GC G +G KG+RG  G+
Sbjct: 1837 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 1896

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
            +GEVGE G+DGL+GE GD GLPG  GEKG+ G +G  G RG  G+RG  G+RGDPG PG 
Sbjct: 1897 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 1956

Query: 1517 DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG 1576
            DS   GP G  G+ G  G  G  G PG PG   K    GRRG  G +G  G PG  G EG
Sbjct: 1957 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2016

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
              G +G QGP G AG  G  G  G  GP+G  G  G  G +GR G  G KGEPG+ G KG
Sbjct: 2017 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2076

Query: 1637 AVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGK 1696
             +G  GPRG  G+DG  G GS GR+G KG+ GFPG  GPKG  G+PG  G TG KG RG+
Sbjct: 2077 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2136

Query: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPT 1756
              ++G PG +G  G+PG PG  G KG +G  S   C LIQ ++D+ P  +G  ECPV PT
Sbjct: 2137 RGNSGPPGIVGQKGDPGYPGPAGPKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPT 2195

Query: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816
            EL FALD S  V +  F RM++++  +V D+ + E++CP GA +A+++YN+     +RF+
Sbjct: 2196 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2255

Query: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSA 1876
            D+ +KS LL +I+ +    +S  + +  AM F++RN FKR   G   RK+A FFS+  + 
Sbjct: 2256 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTR 2315

Query: 1877 DAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERL 1936
             +  +  A ++     I P+ +T      +  A  I++T     +V+P+G D    LE +
Sbjct: 2316 ASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENV 2375

Query: 1937 QRCTFCYDVCKPDASCD---------QARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987
              C  C D+C  D SC            R       +D AF+LD++      +F +++ +
Sbjct: 2376 LTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKY 2435

Query: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047
            +  L+   +++P+P+ S    RVA++ HAP + + N    PV+ EF+LT Y SK  +   
Sbjct: 2436 IAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDF 2495

Query: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107
            +   + QL G   +G A+++T++NVF S PN R  K++ ++  GE      E  ++  L+
Sbjct: 2496 LSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQ 2555

Query: 2108 AKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138
            AKC+GY   V  +G   + KE+   AS P D
Sbjct: 2556 AKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2586



 Score =  436 bits (1122), Expect = e-121
 Identities = 326/1202 (27%), Positives = 591/1202 (49%), Gaps = 60/1202 (4%)

Query: 19   QDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSE 78
            Q +  + AD++FL+D S+  GS +F  +  F+  ++  LPI   + RV + Q+SD+  + 
Sbjct: 28   QQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTM 87

Query: 79   FHLSTFKGRSPMLNHLRKNFGFIGGSL-QIGKALQEAHRTYFSAPANGRDKKQFPPILVV 137
            F L T+  ++ +L  + K  GF GG L  IG AL      +F+     R ++  P +LV+
Sbjct: 88   FSLDTYSTKAQVLGAV-KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146

Query: 138  LASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMAT-SQFHFNLRTVRDLSMFS 196
            +++  S D +     AL++  V    +G Q AS   L+ +AT     F +   R      
Sbjct: 147  ISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQ 206

Query: 197  QNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESV 256
            + +   I  V +          V      +  D+VFL+D S      NF+ ++ F+ + +
Sbjct: 207  EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266

Query: 257  SALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKA-YTGAAIKKL 315
              L+I ++ ++V +  Y++  +     +    K EV+  ++ + P  G A YTG+A+  +
Sbjct: 267  QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326

Query: 316  RKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQL 375
            R  +F++  G R  +G+P++ VL+T   S D +++ A  L+R  +  F +G +GA   +L
Sbjct: 327  RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386

Query: 376  EKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA 435
            E+IA   +  ++      A L       L  LR     T+S   E         V + + 
Sbjct: 387  EEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLR-----TLSGTPE---------VHSNKR 432

Query: 436  DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
            DI  L+DGS +   T+F  ++ F+  +V   +I    +RVG VQ++D+   EF +N Y  
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492

Query: 496  KQDLGKAIENIRQMGGN-TNTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDS 552
            K D+   +  ++  GG+  NTG+AL++  +    +    +    VP  L++LT G S+DS
Sbjct: 493  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 552

Query: 553  ILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICT 612
             L+ AN L    I  + +G  +AN+ +L +IA     VY + DF +L  +  Q++Q + T
Sbjct: 553  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTT 612

Query: 613  ------EE---ACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGV 663
                  EE   A  E K DI+FL D S ++  + F  ++ F+  ++ +  + P+  +I V
Sbjct: 613  YVSGGVEEVPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAV 671

Query: 664  VQFSDINKEEFQLNRFMSQSDISNAIDQM-AHIGQTTLTGSALSFVSQY-FSPTKGAR-- 719
             Q+SD  K E + +   S+ +I N + +M    G+    G AL +  +Y F  + G+R  
Sbjct: 672  AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731

Query: 720  PNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVE 779
              + +FL+L+  G + D V  PA  L+Q GV+ +      ++  +LE+I   P  +   E
Sbjct: 732  DGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791

Query: 780  NFDILQRIEDDLVFGICSPREECKR--IEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837
            +   +  +   +V  + S             DVVF++D S  +    + ++K+F+  +V+
Sbjct: 792  SLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVE 850

Query: 838  KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST-YTAEALGF-S 895
              DVG+++VR   ++Y+D     FYL+ +  K +V++ ++    +GG T  T  AL F  
Sbjct: 851  SLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVL 910

Query: 896  DHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955
             ++   + GSR+ +GVPQ+LIV+T   S   D +   +  ++  G + + +GI  A+  E
Sbjct: 911  RNILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGAVPIGIGIGNADITE 968

Query: 956  LLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEI--------------DKVDL 1001
            +  ++   D    + TF  L  +   ++  V   ++ +                  K D+
Sbjct: 969  MQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDV 1028

Query: 1002 VFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEK 1061
            VFL+DGS S  P +F+ ++  +  +V   DV  +  R+   QFSD    EF L     + 
Sbjct: 1029 VFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKD 1087

Query: 1062 EISFQIENIKQIFG-NTHIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVA 1119
            E+   ++ ++   G   ++G AL  V  + F+  +GSRI  G PQ L++++ G+S DEV 
Sbjct: 1088 EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVD 1147

Query: 1120 QAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTA 1179
              A  L+  G+  +++   + D ++L++I+ + E   +V  F EL  + ++++  I T  
Sbjct: 1148 DPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLT 1206

Query: 1180 GE 1181
             E
Sbjct: 1207 SE 1208



 Score =  255 bits (652), Expect = 3e-67
 Identities = 170/588 (28%), Positives = 313/588 (53%), Gaps = 25/588 (4%)

Query: 613  EEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKE 672
            ++   +  ADI+FL+D S + G  NF+ +  F+ NL+ K  IG  ++++GVVQFSD  + 
Sbjct: 27   QQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRT 86

Query: 673  EFQLNRFMSQSDISNAIDQMAHI-GQTTLTGSALSF-VSQYFSPTKGAR--PNIRKFLIL 728
             F L+ + +++ +  A+  +    G+    G AL F V  +F+   G+R    + + L+L
Sbjct: 87   MFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146

Query: 729  ITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIE 788
            I+ G + D ++   V L+Q  V  + +G   ++  +L+ I+    +VF V  F     ++
Sbjct: 147  ISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQ 206

Query: 789  DDL---VFGICS-------PREECKRIEV--LDVVFVIDSSGSIDYDEYNIMKDFMIGLV 836
            + L   + G+         P    + IEV   D+VF++D S ++    +N ++DF+  ++
Sbjct: 207  EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266

Query: 837  KKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST-YTAEALGF- 894
            ++ ++G++ ++    +YAD     FY +   TK EVI+ ++  + + GS  YT  AL F 
Sbjct: 267  QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326

Query: 895  SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPV 954
             +++FT + G R  +G+P++L++IT G+S   D+++  A+ L+   I+  A+G  GA+  
Sbjct: 327  RNNLFTSSAGYRAAEGIPKLLVLITGGKS--LDEISQPAQELKRSSIMAFAIGNKGADQA 384

Query: 955  ELLAMAGSSDKYFFVETF--GGLKGIFSDVTASVCN-SSKVDCEIDKVDLVFLMDGSTSI 1011
            EL  +A  S   F    F    L+G+   + A +   S   +   +K D++FL+DGS ++
Sbjct: 385  ELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANV 444

Query: 1012 QPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIK 1071
               +F  +++F+ ++V   D+  + +R+G  QFSDT   EF L T+  + +I   +  ++
Sbjct: 445  GKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQ 504

Query: 1072 QIFGN-THIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRG 1129
               G+  + G+AL  V  ++F    GSRI    PQ+LL+LT GQS+D   QAA AL   G
Sbjct: 505  LQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAG 564

Query: 1130 IDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICT 1177
            I  + VG    +  +L QI         + +F  L  + +++++ + T
Sbjct: 565  ILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTT 612



 Score =  154 bits (390), Expect = 7e-37
 Identities = 141/559 (25%), Positives = 251/559 (44%), Gaps = 36/559 (6%)

Query: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85
            AD+VFL+DSS+ +    F  ++ F+++++  L I   K RV + Q+S+ +  EF+L T++
Sbjct: 1229 ADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYR 1288

Query: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145
             ++P+L+ +R+     G  L  GKAL+   R  F   A  R +   P  LV++   +S+D
Sbjct: 1289 SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD 1348

Query: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATS-QFHFNLRTVRDLSMFSQNMTHIIK 204
            +V   ++ +R  G+  + VG +      L+ +    +  F +R  R+L    + + +   
Sbjct: 1349 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFG 1408

Query: 205  DVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN 264
                       D    +      AD+VFLLD SIN   ++F  +  F+ E V  +    +
Sbjct: 1409 PSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGD 1468

Query: 265  CMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFSAR 323
             ++VGLV Y+++      L     K +++  I  +  + G+ A T   ++ LR   F   
Sbjct: 1469 SIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPE 1528

Query: 324  NGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPA 383
             GSR +Q VPQIA ++T   S ++    ++ L + GV +F +G+      ++ KIAS+ A
Sbjct: 1529 AGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA 1588

Query: 384  EQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA-DIYLLID 442
              +             N   L +L  Q+  T  +     ETL  G  D  +A ++ +++ 
Sbjct: 1589 TAF----------RVGNVQELSELSEQVLET--LHDAMHETLCPGVTDAAKACNLDVILG 1636

Query: 443  GSGSTQATDFHEMKTFLSEVVGMFNIAPH------------KVRVGAVQYADSWDLE-FE 489
              GS     F   K F S+V  + N                 VRV  V    S  +E F+
Sbjct: 1637 FDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD 1696

Query: 490  INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMS 549
             ++Y  + ++ +   N+R       T   L   L+  +++      KV  H    T+G  
Sbjct: 1697 FDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPD-SVKVVIH---FTDGAD 1750

Query: 550  KD--SILEPANRLREEHIR 566
             D   +   +  LR+E +R
Sbjct: 1751 GDLADLHRASENLRQEGVR 1769



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%)

Query: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
            G PE   +  +++F LD S +V +  F  +++ +  LV  + +  ++  VG         
Sbjct: 423  GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 473

Query: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856
                 LV+FSD             KS +L  +  +  +  S     G A+ ++  N F  
Sbjct: 474  -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 527

Query: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913
               +    H  ++    ++GQS D++     A+    +    V  + +N   + +  A +
Sbjct: 528  AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 586

Query: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973
             +    ++ +      +PAL +         V         A+P   +S  D  FL D S
Sbjct: 587  PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 639

Query: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033
             N+   +F  +R FL  ++D   + PE      G R+A+  ++            V+ E 
Sbjct: 640  ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 682

Query: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084
                ++SK     L+KR   ++ K LN    +G+AL +    +F+ +   R        +
Sbjct: 683  RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 738

Query: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136
            + +++   +  +DG      +   K  G   F+F      D  ELE +   P
Sbjct: 739  VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 784



 Score = 33.5 bits (75), Expect = 2.4
 Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 28/142 (19%)

Query: 1961 QSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDF 2020
            Q   D  FL+D S N GS  F  I  FL  LL+   I     T      V   S  P   
Sbjct: 32   QDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI----GTQQIRVGVVQFSDEP--- 84

Query: 2021 LPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQL---NGD-AFIGHALQWTLDNVFLST 2076
                     R  F+L TY +    K  V  +VK L    G+ A IG AL + ++N F   
Sbjct: 85   ---------RTMFSLDTYST----KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRA 131

Query: 2077 PNLRRN----KVIFVISAGETS 2094
               R      +V+ +ISAG +S
Sbjct: 132  GGSRVEEGVPQVLVLISAGPSS 153


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 1144 bits (2960), Expect = 0.0
 Identities = 730/2191 (33%), Positives = 1148/2191 (52%), Gaps = 116/2191 (5%)

Query: 27   DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
            D++FL+D S  +G  +FP+V+ F+  +++SL I  D  RV L Q+SD   +EF L+T++ 
Sbjct: 639  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698

Query: 87   RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
            +S +L HLR+     G  L  G AL   +  +F+     R ++  P +L++L + +SED+
Sbjct: 699  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 758

Query: 147  VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206
              +A+ AL + G+    VG  +A++  L+ +A +     L  + D S        +I+ +
Sbjct: 759  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQPL 816

Query: 207  IKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM 266
              Y  G V++  V   Q  S  D++FL D S N   + F  ++ FL + +  L++K    
Sbjct: 817  TTYVSGGVEE--VPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGT 873

Query: 267  RVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARNG 325
            R+ +  YS++ KV +      +K E+L  ++ +  +TGKA   G A+   ++ +F    G
Sbjct: 874  RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 933

Query: 326  SRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQ 385
            SR   GV Q  VL+    S D V   A NL++ GV  F    + A   +LE+I   PA  
Sbjct: 934  SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 993

Query: 386  YVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444
              ++ L    DL       LK + N     VS                 E D+  L+DGS
Sbjct: 994  LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDGS 1037

Query: 445  GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504
               ++  F  +K F+  VV   ++   +VRV  VQY+D    EF +N Y NKQD+  A+ 
Sbjct: 1038 EGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 1096

Query: 505  NIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561
             +  +GG T NTGAAL F L   L+  A  +    VP  L+VLT   S D +  P+  ++
Sbjct: 1097 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVK 1156

Query: 562  EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM-- 619
                    IGI  A+ T+++ I+        +  F  L  ++ QV+ E  T+   +E+  
Sbjct: 1157 RGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELSR 1215

Query: 620  ---------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVV 664
                           K D++FL+D S S GPE F  ++T ++ LV    +G D  ++ V+
Sbjct: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVI 1274

Query: 665  QFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLT-GSALSFVSQ-YFSPTKGAR--P 720
            QFSD  K EF LN   S+ ++ NA+ ++   G   +  G+AL +VS+  F    G+R   
Sbjct: 1275 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1334

Query: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780
             + +FL+LI+ G++ D V +PAV L+Q GV  +++    ++  +L +IS  PE VF V  
Sbjct: 1335 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIAR-NADQEELVKISLSPEYVFSVST 1393

Query: 781  FDILQRIEDDLVFGICS-PREECKRI-------------EVLDVVFVIDSSGSIDYDEYN 826
            F  L  +E  L+  I +   E+ +++             +  D+VF+IDSS  +  D + 
Sbjct: 1394 FRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFA 1453

Query: 827  IMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST 886
             ++DF+  +V++ ++G ++VR G +++++D    FYL  + ++  V+  ++  +  GGS 
Sbjct: 1454 HIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSP 1513

Query: 887  Y-TAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVL 944
              T +AL F + ++F ++ GSR+  GVPQ L+++  G+S D   ++  A+ +R  GI+ L
Sbjct: 1514 LNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSGIVSL 1571

Query: 945  AVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDC---------- 994
             VG    +  EL  +       F V  F  L  I   +  S   S+              
Sbjct: 1572 GVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPS 1631

Query: 995  --EIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEF 1052
              E  K D+VFL+DGS + + + F+++  F++ +V       + +++G  Q++     EF
Sbjct: 1632 RPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEF 1691

Query: 1053 PLGTFIGEKEISFQIENIKQIFG---NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVL 1109
             L  F  +++I   I  +    G   NT +G     V H F P+ GSR++   PQ+  V+
Sbjct: 1692 FLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH-FVPEAGSRLDQRVPQIAFVI 1750

Query: 1110 TDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169
            T G+S ++    + AL  RG+ +++VG+ ++D +++ +I   +     V N  EL ++++
Sbjct: 1751 TGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSE 1810

Query: 1170 RIVRNI--------C--TTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILR 1219
            +++  +        C   T     C +DV++GFD S   + Q +   Q   E+ +  IL 
Sbjct: 1811 QVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKVDAILN 1867

Query: 1220 AISSLNGVSCEVGTETQVSVAFQV---TNAMEKYSPKFEIYSENILNSLKDITVKGPSLL 1276
             IS ++ VSC  G    V V+      +  +E +   F+ Y   +L   +++  + P +L
Sbjct: 1868 RISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD--FDEYQPEMLEKFRNMRSQHPYVL 1925

Query: 1277 NANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGP 1336
              + L    + F+  S    KVV+ F+DG D D+  L + S+ LR+EG+ ALI V L+  
Sbjct: 1926 TEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERV 1985

Query: 1337 ADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGT 1396
             +   L  L ++EFG+GF Y   L + + +L   L++QL N+AE+ CC + CKC G  G 
Sbjct: 1986 VN---LERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGD 2042

Query: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
             G  G  G +G PG  G  GY G+EG  GERG PG  G QG +GC G +G KG+RG  G+
Sbjct: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
            +GEVGE G+DGL+GE GD GLPG  GEKG+ G +G  G RG  G+RG  G+RGDPG PG 
Sbjct: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162

Query: 1517 DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG 1576
            DS   GP G  G+ G  G  G  G PG PG   K    GRRG  G +G  G PG  G EG
Sbjct: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
              G +G QGP G AG  G  G  G  GP+G  G  G  G +GR G  G KGEPG+ G KG
Sbjct: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282

Query: 1637 AVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGK 1696
             +G  GPRG  G+DG  G GS GR+G KG+ GFPG  GPKG  G+PG  G TG KG RG+
Sbjct: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342

Query: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPT 1756
              ++G PG +G  G+PG PG  G KG +G  S   C LIQ ++D+ P  +G  ECPV PT
Sbjct: 2343 RGNSGPPGIVGQKGDPGYPGPAGPKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPT 2401

Query: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816
            EL FALD S  V +  F RM++++  +V D+ + E++CP GA +A+++YN+     +RF+
Sbjct: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461

Query: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSA 1876
            D+ +KS LL +I+ +    +S  + +  AM F++RN FKR   G   RK+A FFS+  + 
Sbjct: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTR 2521

Query: 1877 DAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERL 1936
             +  +  A ++     I P+ +T      +  A  I++T     +V+P+G D    LE +
Sbjct: 2522 ASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENV 2581

Query: 1937 QRCTFCYDVCKPDASCD---------QARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987
              C  C D+C  D SC            R       +D AF+LD++      +F +++ +
Sbjct: 2582 LTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKY 2641

Query: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047
            +  L+   +++P+P+ S    RVA++ HAP + + N    PV+ EF+LT Y SK  +   
Sbjct: 2642 IAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDF 2701

Query: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107
            +   + QL G   +G A+++T++NVF S PN R  K++ ++  GE      E  ++  L+
Sbjct: 2702 LSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQ 2761

Query: 2108 AKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138
            AKC+GY   V  +G   + KE+   AS P D
Sbjct: 2762 AKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792



 Score =  478 bits (1230), Expect = e-134
 Identities = 338/1185 (28%), Positives = 613/1185 (51%), Gaps = 52/1185 (4%)

Query: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85
            AD++FLVDSS  +G + F  V+ F+  ++ SL +  + +  AL Q++   H+EF L+T++
Sbjct: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97

Query: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145
             +  +L+H+  N  +IGG+ Q GK L+   +++ +  A  R     P ++VVL    S+D
Sbjct: 98   TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156

Query: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFH---FNLRTVRDLSMFSQNMTHI 202
             +   S  L+   V + ++GV+ A E  LK +A+   +   FNL     L     N+   
Sbjct: 157  GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216

Query: 203  IKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIK 262
            +   +   E A D   ++       AD++FL+D S N    NF  +  FL   +  L I 
Sbjct: 217  VHSSVS-PERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIG 275

Query: 263  ENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFS 321
               +RVG+V +S+E + + SL     K++VL  ++ L    G+ A  G A+  + +  F+
Sbjct: 276  TQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFT 335

Query: 322  ARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASH 381
               GSR  +GVPQ+ VL++   S D +    V L++  V  F LG + AS  +L+ IA+ 
Sbjct: 336  RAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD 395

Query: 382  PAEQY-VSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLL 440
                + V + ++F DL      ++  +  +  H V     +  T+ +  ++  + DI  L
Sbjct: 396  DNLVFTVPEFRSFGDLQEKLLPYIVGVAQR--HIVL----KPPTIVTQVIEVNKRDIVFL 449

Query: 441  IDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLG 500
            +DGS +    +F+ ++ F+++V+    I    ++V   QYAD+   EF  N +  K+++ 
Sbjct: 450  VDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVI 509

Query: 501  KAIENIRQMGGNT-NTGAALNFTLSLL--QKAKKQRGNKVPCHLVVLTNGMSKDSILEPA 557
             A+  ++ + G+   TG+AL+F  + L    A  +    +P  LV++T G S D I +PA
Sbjct: 510  TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPA 569

Query: 558  NRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDA--LKDIRNQVVQEICTEEA 615
              L+   I  +AIG K A+Q +L EIA +   V+   +F A  L+ +   ++  + T   
Sbjct: 570  QELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSG 629

Query: 616  CKEM---KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKE 672
              E+   K DI+FL+D S ++G  NF  ++ F+ NLV+   IG D +++G+VQFSD    
Sbjct: 630  TPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVT 689

Query: 673  EFQLNRFMSQSDISNAIDQMAHIGQTTL-TGSALSFV-SQYFSPTKGA--RPNIRKFLIL 728
            EF LN + ++SDI   + Q+   G + L TGSALS+V + +F+   G+  R ++ + L+L
Sbjct: 690  EFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749

Query: 729  ITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIE 788
            +T G+++D   + A  L + G++ + VG   +N  +LE+I+  P +V+ +++F  L  + 
Sbjct: 750  LTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALP 809

Query: 789  DDLVFGICS-----------PREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837
              L+  + +            + E KR    D++F+ D S ++   ++ +++DF+  ++ 
Sbjct: 810  QQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANL-VGQFPVVRDFLYKIID 864

Query: 838  KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYT-AEALGFSD 896
            + +V     R    +Y+DD +V    D+  +K E++++++  +   G       AL ++ 
Sbjct: 865  ELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQ 924

Query: 897  -HMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955
             ++F ++ GSR+  GV Q L+++  G S  +D+++  A  L+  G++        A+P E
Sbjct: 925  RYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNADPAE 982

Query: 956  LLAMAGSSDKYFFVET---FGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQ 1012
            L  +  S       E+    G L     ++  SV N +      +K D+VFL+DGS  ++
Sbjct: 983  LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK-DVVFLLDGSEGVR 1041

Query: 1013 PNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQ 1072
             + F  +KEF+  VV+  DV  +RVR+   Q+SD   PEF L +++ ++++   +  +  
Sbjct: 1042 -SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTL 1100

Query: 1073 IFGNT-HIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGI 1130
            + G T + GAAL  V  +      GSRI  G PQ+L+VLT  +S D+V   +  ++  G 
Sbjct: 1101 LGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGA 1160

Query: 1131 DIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNI 1175
                +GIG+ D  ++  I+   +  + +  F +L  V + I   +
Sbjct: 1161 VPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205



 Score =  382 bits (980), Expect = e-105
 Identities = 299/1096 (27%), Positives = 533/1096 (48%), Gaps = 82/1096 (7%)

Query: 228  ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGI 287
            AD++FL+D S    EE+F  ++ FL + V +L + EN     LV ++        L+   
Sbjct: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97

Query: 288  NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDN 347
             K EVL HI N+S   G   TG  ++ + +   +   GSR   GVPQ+ V++T   S+D 
Sbjct: 98   TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157

Query: 348  VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
            +   +  L+   V +F +G+E A +  L++IAS P   ++  L+ F        T L  +
Sbjct: 158  LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENF--------TSLHDI 209

Query: 408  RNQITHTV--SVFSER---TETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEV 462
               +   V  SV  ER   TETLK      + ADI  LIDGS +T + +F  +  FL  +
Sbjct: 210  VGNLVSCVHSSVSPERAGDTETLKD-ITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268

Query: 463  VGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGN-TNTGAALNF 521
            +    I   ++RVG VQ++D     F ++ YS K  +  A++ +   GG   N G AL+F
Sbjct: 269  LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328

Query: 522  TLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQ 579
             +     +    +    VP  LV+++ G S D I      L++  +  + +G + A++ +
Sbjct: 329  VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388

Query: 580  LREIAGEEKRVYYVHDFDALKDIRNQVVQEI--------------CTEEACKEMKADIMF 625
            L+ IA ++  V+ V +F +  D++ +++  I                 +  +  K DI+F
Sbjct: 389  LQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVF 448

Query: 626  LVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDI 685
            LVD S ++G  NF+ ++ F+  ++ + +IG D +Q+ V Q++D  + EF  N   ++ ++
Sbjct: 449  LVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREV 508

Query: 686  SNAIDQMAHI-GQTTLTGSALSFV-SQYFSPTKG--ARPNIRKFLILITDGEAQDIVKEP 741
              A+ +M  + G    TGSAL FV +  F+ + G  A   I K L+LIT G++ D + +P
Sbjct: 509  ITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQP 568

Query: 742  AVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREE 801
            A  L++  ++ +++G  G++  +LEEI+    +VF    F         ++ G+ +P   
Sbjct: 569  AQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPL--QGMLPGLLAPLRT 626

Query: 802  CKRIEVL-----DVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADD 856
                  +     D++F++D S ++    +  ++DF++ LV   D+G + +R G ++++D 
Sbjct: 627  LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDT 686

Query: 857  PEVLFYLDDFGTKLEVISVLQNDQAMGGS---TYTAEALGFSDHMFTEARGSRLNKGVPQ 913
            P   F L+ + TK +++  L+  Q  GGS   T +A +  +++H FTEA GSR+ + VPQ
Sbjct: 687  PVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH-FTEAGGSRIREHVPQ 745

Query: 914  VLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFG 973
            +L+++T G+S D+      A AL   GIL   VG   AN  EL  +A +    + ++ F 
Sbjct: 746  LLLLLTAGQSEDS--YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFS 803

Query: 974  GLKGIFSDVTASVCNSSKVDCE-------IDKVDLVFLMDGSTSIQPNDFKKMKEFLASV 1026
             L  +   +   +        E         K D++FL DGS ++    F  +++FL  +
Sbjct: 804  SLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKI 862

Query: 1027 VQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNT-HIGAALRE 1085
            + + +V     RI  AQ+SD    E        + EI   ++ +K   G   ++G AL  
Sbjct: 863  IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDY 922

Query: 1086 VEHY-FRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQ 1144
             + Y F    GSRI  G  Q L++L  G+S D V   A  L+  G+  +     + D  +
Sbjct: 923  AQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAE 982

Query: 1145 LIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFV----DVVVGFDVSTQEKG 1200
            L QI  +    L   +  ++  ++ +IV  + +    +   V    DVV   D S     
Sbjct: 983  LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS----- 1037

Query: 1201 QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYS-- 1258
            + +  G P ++ ++Q ++         S +VG   Q  V   V    ++  P+F + S  
Sbjct: 1038 EGVRSGFPLLKEFVQRVVE--------SLDVG---QDRVRVAVVQYSDRTRPEFYLNSYM 1086

Query: 1259 --ENILNSLKDITVKG 1272
              ++++N+++ +T+ G
Sbjct: 1087 NKQDVVNAVRQLTLLG 1102



 Score =  154 bits (390), Expect = 7e-37
 Identities = 141/559 (25%), Positives = 251/559 (44%), Gaps = 36/559 (6%)

Query: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85
            AD+VFL+DSS+ +    F  ++ F+++++  L I   K RV + Q+S+ +  EF+L T++
Sbjct: 1435 ADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYR 1494

Query: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145
             ++P+L+ +R+     G  L  GKAL+   R  F   A  R +   P  LV++   +S+D
Sbjct: 1495 SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD 1554

Query: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATS-QFHFNLRTVRDLSMFSQNMTHIIK 204
            +V   ++ +R  G+  + VG +      L+ +    +  F +R  R+L    + + +   
Sbjct: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFG 1614

Query: 205  DVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN 264
                       D    +      AD+VFLLD SIN   ++F  +  F+ E V  +    +
Sbjct: 1615 PSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGD 1674

Query: 265  CMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFSAR 323
             ++VGLV Y+++      L     K +++  I  +  + G+ A T   ++ LR   F   
Sbjct: 1675 SIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPE 1734

Query: 324  NGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPA 383
             GSR +Q VPQIA ++T   S ++    ++ L + GV +F +G+      ++ KIAS+ A
Sbjct: 1735 AGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA 1794

Query: 384  EQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA-DIYLLID 442
              +             N   L +L  Q+  T  +     ETL  G  D  +A ++ +++ 
Sbjct: 1795 TAF----------RVGNVQELSELSEQVLET--LHDAMHETLCPGVTDAAKACNLDVILG 1842

Query: 443  GSGSTQATDFHEMKTFLSEVVGMFNIAPH------------KVRVGAVQYADSWDLE-FE 489
              GS     F   K F S+V  + N                 VRV  V    S  +E F+
Sbjct: 1843 FDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD 1902

Query: 490  INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMS 549
             ++Y  + ++ +   N+R       T   L   L+  +++      KV  H    T+G  
Sbjct: 1903 FDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPD-SVKVVIH---FTDGAD 1956

Query: 550  KD--SILEPANRLREEHIR 566
             D   +   +  LR+E +R
Sbjct: 1957 GDLADLHRASENLRQEGVR 1975



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 78/362 (21%), Positives = 140/362 (38%), Gaps = 65/362 (17%)

Query: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816
            +++F +D S  + E+ F+ ++E +  +V+ + V EN      H A++ +N +       +
Sbjct: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF----HFALVQFNGNPHTEFLLN 94

Query: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTL---PGAHTRKIATFFSSG 1873
                K ++L  I  + Y     + + G+ + +I ++   +      G    ++    + G
Sbjct: 95   TYRTKQEVLSHISNMSY--IGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152

Query: 1874 QSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPAL 1933
             S D  ++ +A ++   + +  + +  +            D G  + I   +       +
Sbjct: 153  HSKDGLALPSAELKSADVNVFAIGVEDA------------DEGALKEI---ASEPLNMHM 197

Query: 1934 ERLQRCTFCYDVCKPDASCDQARPPP-------------VQSYMDAAFLLDASRNMGSAE 1980
              L+  T  +D+     SC  +   P              Q   D  FL+D S N GS  
Sbjct: 198  FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257

Query: 1981 FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS 2040
            F  I  FL  LL+   I     T      V   S  P            R  F+L TY +
Sbjct: 258  FAVILDFLVNLLEKLPI----GTQQIRVGVVQFSDEP------------RTMFSLDTYST 301

Query: 2041 KRLMKRHVHESVKQL---NGD-AFIGHALQWTLDNVFLSTPNLRRN----KVIFVISAGE 2092
                K  V  +VK L    G+ A IG AL + ++N F      R      +V+ +ISAG 
Sbjct: 302  ----KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGP 357

Query: 2093 TS 2094
            +S
Sbjct: 358  SS 359



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%)

Query: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
            G PE   +  +++F LD S +V +  F  +++ +  LV  + +  ++  VG         
Sbjct: 629  GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 679

Query: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856
                 LV+FSD             KS +L  +  +  +  S     G A+ ++  N F  
Sbjct: 680  -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 733

Query: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913
               +    H  ++    ++GQS D++     A+    +    V  + +N   + +  A +
Sbjct: 734  AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 792

Query: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973
             +    ++ +      +PAL +         V         A+P   +S  D  FL D S
Sbjct: 793  PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 845

Query: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033
             N+   +F  +R FL  ++D   + PE      G R+A+  ++            V+ E 
Sbjct: 846  ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 888

Query: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084
                ++SK     L+KR   ++ K LN    +G+AL +    +F+ +   R        +
Sbjct: 889  RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 944

Query: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136
            + +++   +  +DG      +   K  G   F+F      D  ELE +   P
Sbjct: 945  VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 990


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 1116 bits (2887), Expect = 0.0
 Identities = 722/2192 (32%), Positives = 1136/2192 (51%), Gaps = 124/2192 (5%)

Query: 27   DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
            D+VFLVD S  LG  +F  ++ FI K+I  L I  D  +VA+AQY+D +  EF+ +T   
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 87   RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
            +  ++  +RK     G +L  G AL       F++ A  R  +  P +LV++   +S D 
Sbjct: 98   KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 147  VEEASKALRKDGVKIISVGVQKASEENLKAMA-TSQFHFNLRTVRDLSMFSQNMTHIIKD 205
            + + ++ L++  +   ++G + A +  L+ +A  S   F     R   +  Q M   +  
Sbjct: 158  ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPL--QGMLPGLLA 215

Query: 206  VIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENC 265
             ++   G  ++         S  D++FL D S N   + F  ++ FL + +  L++K   
Sbjct: 216  PLRTLSGTPEE---------SKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEG 265

Query: 266  MRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARN 324
             R+ +  YS++ KV +      +K E+L  ++ +  +TGKA   G A+   ++ +F    
Sbjct: 266  TRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSA 325

Query: 325  GSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAE 384
            GSR   GV Q  VL+    S D V   A NL++ GV  F    + A   +LE+I   PA 
Sbjct: 326  GSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAF 385

Query: 385  QYVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDG 443
               ++ L    DL       LK + N     VS                 E D+  L+DG
Sbjct: 386  ILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDG 429

Query: 444  SGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAI 503
            S   ++  F  +K F+  VV   ++   +VRV  VQY+D    EF +N Y NKQD+  A+
Sbjct: 430  SEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV 488

Query: 504  ENIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRL 560
              +  +GG T NTGAAL F L   L+  A  +    VP  L+VLT   S D +  P+  +
Sbjct: 489  RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV 548

Query: 561  REEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM- 619
            +        IGI  A+ T+++ I+        +  F  L  ++ QV+ E  T+   +E+ 
Sbjct: 549  KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELS 607

Query: 620  ----------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGV 663
                            K D++FL+D S S GPE F  ++T ++ LV    +G D  ++ V
Sbjct: 608  RLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAV 666

Query: 664  VQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLT-GSALSFVSQ-YFSPTKGAR-- 719
            +QFSD  K EF LN   S+ ++ NA+ ++   G   +  G+AL +VS+  F    G+R  
Sbjct: 667  IQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIE 726

Query: 720  PNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVE 779
              + +FL+LI+ G++ D V +PAV L+Q GV  +++    ++  +L +IS  PE VF V 
Sbjct: 727  EGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIAR-NADQEELVKISLSPEYVFSVS 785

Query: 780  NFDILQRIEDDLVFGICS-PREECKRI-------------EVLDVVFVIDSSGSIDYDEY 825
             F  L  +E  L+  I +   E+ +++             +  D+VF+IDSS  +  D +
Sbjct: 786  TFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGF 845

Query: 826  NIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGS 885
              ++DF+  +V++ ++G ++VR G +++++D    FYL  + ++  V+  ++  +  GGS
Sbjct: 846  AHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGS 905

Query: 886  TY-TAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILV 943
               T +AL F + ++F ++ GSR+  GVPQ L+++  G+S D   ++  A+ +R  GI+ 
Sbjct: 906  PLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSGIVS 963

Query: 944  LAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDC--------- 994
            L VG    +  EL  +       F V  F  L  I   +  S   S+             
Sbjct: 964  LGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPP 1023

Query: 995  ---EIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPE 1051
               E  K D+VFL+DGS + + + F+++  F++ +V       + +++G  Q++     E
Sbjct: 1024 SRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDE 1083

Query: 1052 FPLGTFIGEKEISFQIENIKQIFG---NTHIGAALREVEHYFRPDMGSRINTGTPQVLLV 1108
            F L  F  +++I   I  +    G   NT +G     V H F P+ GSR++   PQ+  V
Sbjct: 1084 FFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH-FVPEAGSRLDQRVPQIAFV 1142

Query: 1109 LTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVN 1168
            +T G+S ++    + AL  RG+ +++VG+ ++D +++ +I   +     V N  EL +++
Sbjct: 1143 ITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELS 1202

Query: 1169 KRIVRNI--------C--TTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDIL 1218
            ++++  +        C   T     C +DV++GFD S   + Q +   Q   E+ +  IL
Sbjct: 1203 EQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKVDAIL 1259

Query: 1219 RAISSLNGVSCEVGTETQVSVAFQV---TNAMEKYSPKFEIYSENILNSLKDITVKGPSL 1275
              IS ++ VSC  G    V V+      +  +E +   F+ Y   +L   +++  + P +
Sbjct: 1260 NRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD--FDEYQPEMLEKFRNMRSQHPYV 1317

Query: 1276 LNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDG 1335
            L  + L    + F+  S    KVV+ F+DG D D+  L + S+ LR+EG+ ALI V L+ 
Sbjct: 1318 LTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLER 1377

Query: 1336 PADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDG 1395
              +   L  L ++EFG+GF Y   L + + +L   L++QL N+AE+ CC + CKC G  G
Sbjct: 1378 VVN---LERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRG 1434

Query: 1396 TMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNG 1455
              G  G  G +G PG  G  GY G+EG  GERG PG  G QG +GC G +G KG+RG  G
Sbjct: 1435 DRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG 1494

Query: 1456 QEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPG 1515
            ++GEVGE G+DGL+GE GD GLPG  GEKG+ G +G  G RG  G+RG  G+RGDPG PG
Sbjct: 1495 EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG 1554

Query: 1516 VDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLE 1575
             DS   GP G  G+ G  G  G  G PG PG   K    GRRG  G +G  G PG  G E
Sbjct: 1555 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 1614

Query: 1576 GSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEK 1635
            G  G +G QGP G AG  G  G  G  GP+G  G  G  G +GR G  G KGEPG+ G K
Sbjct: 1615 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 1674

Query: 1636 GAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARG 1695
            G +G  GPRG  G+DG  G GS GR+G KG+ GFPG  GPKG  G+PG  G TG KG RG
Sbjct: 1675 GGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 1734

Query: 1696 KMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
            +  ++G PG +G  G+PG PG  G KG +G  S   C LIQ ++D+ P  +G  ECPV P
Sbjct: 1735 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFP 1793

Query: 1756 TELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRF 1815
            TEL FALD S  V +  F RM++++  +V D+ + E++CP GA +A+++YN+     +RF
Sbjct: 1794 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 1853

Query: 1816 SDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQS 1875
            +D+ +KS LL +I+ +    +S  + +  AM F++RN FKR   G   RK+A FFS+  +
Sbjct: 1854 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 1913

Query: 1876 ADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALER 1935
              +  +  A ++     I P+ +T      +  A  I++T     +V+P+G D    LE 
Sbjct: 1914 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 1973

Query: 1936 LQRCTFCYDVCKPDASCD---------QARPPPVQSYMDAAFLLDASRNMGSAEFEDIRA 1986
            +  C  C D+C  D SC            R       +D AF+LD++      +F +++ 
Sbjct: 1974 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2033

Query: 1987 FLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKR 2046
            ++  L+   +++P+P+ S    RVA++ HAP + + N    PV+ EF+LT Y SK  +  
Sbjct: 2034 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2093

Query: 2047 HVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESL 2106
             +   + QL G   +G A+++T++NVF S PN R  K++ ++  GE      E  ++  L
Sbjct: 2094 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2153

Query: 2107 RAKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138
            +AKC+GY   V  +G   + KE+   AS P D
Sbjct: 2154 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2185



 Score =  280 bits (717), Expect = 9e-75
 Identities = 211/782 (26%), Positives = 393/782 (50%), Gaps = 36/782 (4%)

Query: 430  VDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFE 489
            ++  + DI  L+DGS +    +F+ ++ F+++V+    I    ++V   QYAD+   EF 
Sbjct: 32   IEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFY 91

Query: 490  INKYSNKQDLGKAIENIRQMGGNT-NTGAALNFTLSLL--QKAKKQRGNKVPCHLVVLTN 546
             N +  K+++  A+  ++ + G+   TG+AL+F  + L    A  +    +P  LV++T 
Sbjct: 92   FNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITG 151

Query: 547  GMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDA--LKDIRN 604
            G S D I +PA  L+   I  +AIG K A+Q +L EIA +   V+   +F A  L+ +  
Sbjct: 152  GKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLP 211

Query: 605  QVVQEICTEEAC-KEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGV 663
             ++  + T     +E K DI+FL D S ++  + F  ++ F+  ++ +  + P+  +I V
Sbjct: 212  GLLAPLRTLSGTPEESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAV 270

Query: 664  VQFSDINKEEFQLNRFMSQSDISNAIDQM-AHIGQTTLTGSALSFVSQY-FSPTKGAR-- 719
             Q+SD  K E + +   S+ +I N + +M    G+    G AL +  +Y F  + G+R  
Sbjct: 271  AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 330

Query: 720  PNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVE 779
              + +FL+L+  G + D V  PA  L+Q GV+ +      ++  +LE+I   P  +   E
Sbjct: 331  DGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 390

Query: 780  NFDILQRIEDDLVFGICSPREECKR--IEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837
            +   +  +   +V  + S             DVVF++D S  +    + ++K+F+  +V+
Sbjct: 391  SLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVE 449

Query: 838  KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST-YTAEALGF-S 895
              DVG+++VR   ++Y+D     FYL+ +  K +V++ ++    +GG T  T  AL F  
Sbjct: 450  SLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVL 509

Query: 896  DHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955
             ++   + GSR+ +GVPQ+LIV+T   S   D +   +  ++  G + + +GI  A+  E
Sbjct: 510  RNILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGAVPIGIGIGNADITE 567

Query: 956  LLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEI--------------DKVDL 1001
            +  ++   D    + TF  L  +   ++  V   ++ +                  K D+
Sbjct: 568  MQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDV 627

Query: 1002 VFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEK 1061
            VFL+DGS S  P +F+ ++  +  +V   DV  +  R+   QFSD    EF L     + 
Sbjct: 628  VFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKD 686

Query: 1062 EISFQIENIKQIFG-NTHIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVA 1119
            E+   ++ ++   G   ++G AL  V  + F+  +GSRI  G PQ L++++ G+S DEV 
Sbjct: 687  EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVD 746

Query: 1120 QAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTA 1179
              A  L+  G+  +++   + D ++L++I+ + E   +V  F EL  + ++++  I T  
Sbjct: 747  DPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLT 805

Query: 1180 GE 1181
             E
Sbjct: 806  SE 807



 Score =  154 bits (390), Expect = 7e-37
 Identities = 141/559 (25%), Positives = 251/559 (44%), Gaps = 36/559 (6%)

Query: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85
            AD+VFL+DSS+ +    F  ++ F+++++  L I   K RV + Q+S+ +  EF+L T++
Sbjct: 828  ADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYR 887

Query: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145
             ++P+L+ +R+     G  L  GKAL+   R  F   A  R +   P  LV++   +S+D
Sbjct: 888  SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD 947

Query: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATS-QFHFNLRTVRDLSMFSQNMTHIIK 204
            +V   ++ +R  G+  + VG +      L+ +    +  F +R  R+L    + + +   
Sbjct: 948  DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFG 1007

Query: 205  DVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN 264
                       D    +      AD+VFLLD SIN   ++F  +  F+ E V  +    +
Sbjct: 1008 PSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGD 1067

Query: 265  CMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFSAR 323
             ++VGLV Y+++      L     K +++  I  +  + G+ A T   ++ LR   F   
Sbjct: 1068 SIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPE 1127

Query: 324  NGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPA 383
             GSR +Q VPQIA ++T   S ++    ++ L + GV +F +G+      ++ KIAS+ A
Sbjct: 1128 AGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA 1187

Query: 384  EQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA-DIYLLID 442
              +             N   L +L  Q+  T  +     ETL  G  D  +A ++ +++ 
Sbjct: 1188 TAF----------RVGNVQELSELSEQVLET--LHDAMHETLCPGVTDAAKACNLDVILG 1235

Query: 443  GSGSTQATDFHEMKTFLSEVVGMFNIAPH------------KVRVGAVQYADSWDLE-FE 489
              GS     F   K F S+V  + N                 VRV  V    S  +E F+
Sbjct: 1236 FDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD 1295

Query: 490  INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMS 549
             ++Y  + ++ +   N+R       T   L   L+  +++      KV  H    T+G  
Sbjct: 1296 FDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPD-SVKVVIH---FTDGAD 1349

Query: 550  KD--SILEPANRLREEHIR 566
             D   +   +  LR+E +R
Sbjct: 1350 GDLADLHRASENLRQEGVR 1368


>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1237

 Score =  436 bits (1122), Expect = e-121
 Identities = 326/1202 (27%), Positives = 591/1202 (49%), Gaps = 60/1202 (4%)

Query: 19   QDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSE 78
            Q +  + AD++FL+D S+  GS +F  +  F+  ++  LPI   + RV + Q+SD+  + 
Sbjct: 28   QQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTM 87

Query: 79   FHLSTFKGRSPMLNHLRKNFGFIGGSL-QIGKALQEAHRTYFSAPANGRDKKQFPPILVV 137
            F L T+  ++ +L  + K  GF GG L  IG AL      +F+     R ++  P +LV+
Sbjct: 88   FSLDTYSTKAQVLGAV-KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146

Query: 138  LASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMAT-SQFHFNLRTVRDLSMFS 196
            +++  S D +     AL++  V    +G Q AS   L+ +AT     F +   R      
Sbjct: 147  ISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQ 206

Query: 197  QNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESV 256
            + +   I  V +          V      +  D+VFL+D S      NF+ ++ F+ + +
Sbjct: 207  EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266

Query: 257  SALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKA-YTGAAIKKL 315
              L+I ++ ++V +  Y++  +     +    K EV+  ++ + P  G A YTG+A+  +
Sbjct: 267  QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326

Query: 316  RKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQL 375
            R  +F++  G R  +G+P++ VL+T   S D +++ A  L+R  +  F +G +GA   +L
Sbjct: 327  RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386

Query: 376  EKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA 435
            E+IA   +  ++      A L       L  LR     T+S   E         V + + 
Sbjct: 387  EEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLR-----TLSGTPE---------VHSNKR 432

Query: 436  DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
            DI  L+DGS +   T+F  ++ F+  +V   +I    +RVG VQ++D+   EF +N Y  
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492

Query: 496  KQDLGKAIENIRQMGGN-TNTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDS 552
            K D+   +  ++  GG+  NTG+AL++  +    +    +    VP  L++LT G S+DS
Sbjct: 493  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 552

Query: 553  ILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICT 612
             L+ AN L    I  + +G  +AN+ +L +IA     VY + DF +L  +  Q++Q + T
Sbjct: 553  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTT 612

Query: 613  ------EE---ACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGV 663
                  EE   A  E K DI+FL D S ++  + F  ++ F+  ++ +  + P+  +I V
Sbjct: 613  YVSGGVEEVPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAV 671

Query: 664  VQFSDINKEEFQLNRFMSQSDISNAIDQM-AHIGQTTLTGSALSFVSQY-FSPTKGAR-- 719
             Q+SD  K E + +   S+ +I N + +M    G+    G AL +  +Y F  + G+R  
Sbjct: 672  AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731

Query: 720  PNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVE 779
              + +FL+L+  G + D V  PA  L+Q GV+ +      ++  +LE+I   P  +   E
Sbjct: 732  DGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791

Query: 780  NFDILQRIEDDLVFGICSPREECKR--IEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837
            +   +  +   +V  + S             DVVF++D S  +    + ++K+F+  +V+
Sbjct: 792  SLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVE 850

Query: 838  KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST-YTAEALGF-S 895
              DVG+++VR   ++Y+D     FYL+ +  K +V++ ++    +GG T  T  AL F  
Sbjct: 851  SLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVL 910

Query: 896  DHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955
             ++   + GSR+ +GVPQ+LIV+T   S   D +   +  ++  G + + +GI  A+  E
Sbjct: 911  RNILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGAVPIGIGIGNADITE 968

Query: 956  LLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEI--------------DKVDL 1001
            +  ++   D    + TF  L  +   ++  V   ++ +                  K D+
Sbjct: 969  MQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDV 1028

Query: 1002 VFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEK 1061
            VFL+DGS S  P +F+ ++  +  +V   DV  +  R+   QFSD    EF L     + 
Sbjct: 1029 VFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKD 1087

Query: 1062 EISFQIENIKQIFG-NTHIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVA 1119
            E+   ++ ++   G   ++G AL  V  + F+  +GSRI  G PQ L++++ G+S DEV 
Sbjct: 1088 EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVD 1147

Query: 1120 QAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTA 1179
              A  L+  G+  +++   + D ++L++I+ + E   +V  F EL  + ++++  I T  
Sbjct: 1148 DPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLT 1206

Query: 1180 GE 1181
             E
Sbjct: 1207 SE 1208



 Score =  255 bits (652), Expect = 3e-67
 Identities = 170/588 (28%), Positives = 313/588 (53%), Gaps = 25/588 (4%)

Query: 613  EEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKE 672
            ++   +  ADI+FL+D S + G  NF+ +  F+ NL+ K  IG  ++++GVVQFSD  + 
Sbjct: 27   QQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRT 86

Query: 673  EFQLNRFMSQSDISNAIDQMAHI-GQTTLTGSALSF-VSQYFSPTKGAR--PNIRKFLIL 728
             F L+ + +++ +  A+  +    G+    G AL F V  +F+   G+R    + + L+L
Sbjct: 87   MFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146

Query: 729  ITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIE 788
            I+ G + D ++   V L+Q  V  + +G   ++  +L+ I+    +VF V  F     ++
Sbjct: 147  ISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQ 206

Query: 789  DDL---VFGICS-------PREECKRIEV--LDVVFVIDSSGSIDYDEYNIMKDFMIGLV 836
            + L   + G+         P    + IEV   D+VF++D S ++    +N ++DF+  ++
Sbjct: 207  EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266

Query: 837  KKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST-YTAEALGF- 894
            ++ ++G++ ++    +YAD     FY +   TK EVI+ ++  + + GS  YT  AL F 
Sbjct: 267  QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326

Query: 895  SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPV 954
             +++FT + G R  +G+P++L++IT G+S   D+++  A+ L+   I+  A+G  GA+  
Sbjct: 327  RNNLFTSSAGYRAAEGIPKLLVLITGGKS--LDEISQPAQELKRSSIMAFAIGNKGADQA 384

Query: 955  ELLAMAGSSDKYFFVETF--GGLKGIFSDVTASVCN-SSKVDCEIDKVDLVFLMDGSTSI 1011
            EL  +A  S   F    F    L+G+   + A +   S   +   +K D++FL+DGS ++
Sbjct: 385  ELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANV 444

Query: 1012 QPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIK 1071
               +F  +++F+ ++V   D+  + +R+G  QFSDT   EF L T+  + +I   +  ++
Sbjct: 445  GKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQ 504

Query: 1072 QIFGN-THIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRG 1129
               G+  + G+AL  V  ++F    GSRI    PQ+LL+LT GQS+D   QAA AL   G
Sbjct: 505  LQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAG 564

Query: 1130 IDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICT 1177
            I  + VG    +  +L QI         + +F  L  + +++++ + T
Sbjct: 565  ILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTT 612



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 70/365 (19%), Positives = 148/365 (40%), Gaps = 41/365 (11%)

Query: 1752 PVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARH 1811
            P    +++F  D S ++  Q F  +++ +  ++ ++ V+    P G  IA+  Y+   + 
Sbjct: 626  PESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSDDVKV 680

Query: 1812 LVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATF-- 1869
              RF +   K ++L  ++ +  +   A   +G A+ +  R +F ++        +  F  
Sbjct: 681  ESRFDEHQSKPEILNLVKRMKIKTGKA-LNLGYALDYAQRYIFVKSAGSRIEDGVLQFLV 739

Query: 1870 -FSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGAD 1928
               +G+S+D   +   A       ++P +    N          D     Q+++ P+   
Sbjct: 740  LLVAGRSSD--RVDGPASNLKQSGVVPFIFQAKNA---------DPAELEQIVLSPA--- 785

Query: 1929 YIPALERLQRCTFCY-DVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987
            +I A E L +    +  +     S     P PV    D  FLLD S  + S  F  ++ F
Sbjct: 786  FILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSG-FPLLKEF 844

Query: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047
            +  +++  ++  +        RVA++ ++             R EF L +Y +K+ +   
Sbjct: 845  VQRVVESLDVGQDRV------RVAVVQYS----------DRTRPEFYLNSYMNKQDVVNA 888

Query: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107
            V +           G AL++ L N+ +S+   R  + +  +    T+   G+ ++  S+ 
Sbjct: 889  VRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVV 948

Query: 2108 AKCQG 2112
             K  G
Sbjct: 949  VKRGG 953



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%)

Query: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
            G PE   +  +++F LD S +V +  F  +++ +  LV  + +  ++  VG         
Sbjct: 423  GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 473

Query: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856
                 LV+FSD             KS +L  +  +  +  S     G A+ ++  N F  
Sbjct: 474  -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 527

Query: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913
               +    H  ++    ++GQS D++     A+    +    V  + +N   + +  A +
Sbjct: 528  AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 586

Query: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973
             +    ++ +      +PAL +         V         A+P   +S  D  FL D S
Sbjct: 587  PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 639

Query: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033
             N+   +F  +R FL  ++D   + PE      G R+A+  ++            V+ E 
Sbjct: 640  ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 682

Query: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084
                ++SK     L+KR   ++ K LN    +G+AL +    +F+ +   R        +
Sbjct: 683  RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 738

Query: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136
            + +++   +  +DG      +   K  G   F+F      D  ELE +   P
Sbjct: 739  VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 784



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 85/396 (21%), Positives = 153/396 (38%), Gaps = 55/396 (13%)

Query: 1753 VHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHL 1812
            V+  ++VF +D S  +    F  +++ +A +++ +++ ++   V    A+  Y    R  
Sbjct: 235  VNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQV----AVAQYADTVRPE 290

Query: 1813 VRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTL---PGAHTRKIATF 1869
              F+    K +++  +  +     SA    G A+ F+  N+F  +          K+   
Sbjct: 291  FYFNTHPTKREVITAVRKMKPLDGSALYT-GSALDFVRNNLFTSSAGYRAAEGIPKLLVL 349

Query: 1870 FSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV----IVVPS 1925
             + G+S D   I+  A E     I+              AFAI + G  Q     I   S
Sbjct: 350  ITGGKSLD--EISQPAQELKRSSIM--------------AFAIGNKGADQAELEEIAFDS 393

Query: 1926 GADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIR 1985
               +IPA  R                     P    +  D  FLLD S N+G   F  +R
Sbjct: 394  SLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVR 453

Query: 1986 AFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMK 2045
             F+  L++  +I  +        RV L+  +          +PV  EF+L TY++K  + 
Sbjct: 454  DFVMNLVNSLDIGND------NIRVGLVQFS---------DTPV-TEFSLNTYQTKSDIL 497

Query: 2046 RHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRN----KVIFVISAGETSHLDGEIL 2101
             H+ +   Q       G AL +   N F      R      +++ +++AG++   D  + 
Sbjct: 498  GHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE--DSYLQ 555

Query: 2102 KKESLRAKCQGYALFVFSLGPIWDDK-ELEDLASHP 2136
               +L        +  F +G    +K ELE +A +P
Sbjct: 556  AANALTRA----GILTFCVGASQANKAELEQIAFNP 587



 Score = 35.8 bits (81), Expect = 0.49
 Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 22/162 (13%)

Query: 1742 SPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIA 1801
            SPG  GK        ++VF +D S+     EF+ ++ ++  LV  + V  ++      +A
Sbjct: 1019 SPGVGGK-------RDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDT----TRVA 1066

Query: 1802 ILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREI--GRAMRFISRNVFKRTLP 1859
            ++ ++   +     +    K ++   ++ +   R    R+I  G A+ ++SRN+FKR L 
Sbjct: 1067 VIQFSDDPKVEFLLNAHSSKDEVQNAVQRL---RPKGGRQINVGNALEYVSRNIFKRPLG 1123

Query: 1860 GAHTRKIATF---FSSGQSADAHSITTAAMEFGALEIIPVVI 1898
                  +  F    SSG+S D   +   A+E     + P  I
Sbjct: 1124 SRIEEGVPQFLVLISSGKSDD--EVDDPAVELKQFGVAPFTI 1163



 Score = 33.5 bits (75), Expect = 2.4
 Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 28/142 (19%)

Query: 1961 QSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDF 2020
            Q   D  FL+D S N GS  F  I  FL  LL+   I     T      V   S  P   
Sbjct: 32   QDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI----GTQQIRVGVVQFSDEP--- 84

Query: 2021 LPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQL---NGD-AFIGHALQWTLDNVFLST 2076
                     R  F+L TY +    K  V  +VK L    G+ A IG AL + ++N F   
Sbjct: 85   ---------RTMFSLDTYST----KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRA 131

Query: 2077 PNLRRN----KVIFVISAGETS 2094
               R      +V+ +ISAG +S
Sbjct: 132  GGSRVEEGVPQVLVLISAGPSS 153


>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1036

 Score =  363 bits (932), Expect = 1e-99
 Identities = 271/990 (27%), Positives = 495/990 (50%), Gaps = 57/990 (5%)

Query: 229  DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
            D+VFL+D S      NF+ ++ F+ + +  L+I ++ ++V +  Y++  +     +    
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 289  KSEVLQHIQNLSPRTGKA-YTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDN 347
            K EV+  ++ + P  G A YTG+A+  +R  +F++  G R  +G+P++ VL+T   S D 
Sbjct: 98   KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 348  VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
            +++ A  L+R  +  F +G +GA   +LE+IA   +  ++      A L       L  L
Sbjct: 158  ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPL 217

Query: 408  RNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFN 467
            R     T+S   E         V + + DI  L+DGS +   T+F  ++ F+  +V   +
Sbjct: 218  R-----TLSGTPE---------VHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263

Query: 468  IAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGN-TNTGAALNFTLS-- 524
            I    +RVG VQ++D+   EF +N Y  K D+   +  ++  GG+  NTG+AL++  +  
Sbjct: 264  IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 323

Query: 525  LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIA 584
              +    +    VP  L++LT G S+DS L+ AN L    I  + +G  +AN+ +L +IA
Sbjct: 324  FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 383

Query: 585  GEEKRVYYVHDFDALKDIRNQVVQEICT------EE---ACKEMKADIMFLVDSSGSIGP 635
                 VY + DF +L  +  Q++Q + T      EE   A  E K DI+FL D S ++  
Sbjct: 384  FNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVG 443

Query: 636  ENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQM-AH 694
            + F  ++ F+  ++ +  + P+  +I V Q+SD  K E + +   S+ +I N + +M   
Sbjct: 444  Q-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIK 502

Query: 695  IGQTTLTGSALSFVSQY-FSPTKGAR--PNIRKFLILITDGEAQDIVKEPAVVLRQEGVI 751
             G+    G AL +  +Y F  + G+R    + +FL+L+  G + D V  PA  L+Q GV+
Sbjct: 503  TGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVV 562

Query: 752  IYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREECKR--IEVLD 809
             +      ++  +LE+I   P  +   E+   +  +   +V  + S             D
Sbjct: 563  PFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKD 622

Query: 810  VVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTK 869
            VVF++D S  +    + ++K+F+  +V+  DVG+++VR   ++Y+D     FYL+ +  K
Sbjct: 623  VVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNK 681

Query: 870  LEVISVLQNDQAMGGST-YTAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDAD 927
             +V++ ++    +GG T  T  AL F   ++   + GSR+ +GVPQ+LIV+T   S   D
Sbjct: 682  QDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRS--GD 739

Query: 928  KLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVC 987
             +   +  ++  G + + +GI  A+  E+  ++   D    + TF  L  +   ++  V 
Sbjct: 740  DVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVT 799

Query: 988  NSSKVDCEI--------------DKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVS 1033
              ++ +                  K D+VFL+DGS S  P +F+ ++  +  +V   DV 
Sbjct: 800  QLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVG 858

Query: 1034 LNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFG-NTHIGAALREV-EHYFR 1091
             +  R+   QFSD    EF L     + E+   ++ ++   G   ++G AL  V  + F+
Sbjct: 859  FDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFK 918

Query: 1092 PDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGT 1151
              +GSRI  G PQ L++++ G+S DEV   A  L+  G+  +++   + D ++L++I+ +
Sbjct: 919  RPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLS 977

Query: 1152 AEKKLTVHNFDELKKVNKRIVRNICTTAGE 1181
             E   +V  F EL  + ++++  I T   E
Sbjct: 978  PEYVFSVSTFRELPSLEQKLLTPITTLTSE 1007



 Score =  351 bits (900), Expect = 5e-96
 Identities = 270/981 (27%), Positives = 486/981 (49%), Gaps = 54/981 (5%)

Query: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
           D+VFLVD S  LG  +F  ++ FI K+I  L I  D  +VA+AQY+D +  EF+ +T   
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 87  RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
           +  ++  +RK     G +L  G AL       F++ A  R  +  P +LV++   +S D 
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 147 VEEASKALRKDGVKIISVGVQKASEENLKAMA-TSQFHFNLRTVRDLSMFSQNMTHIIKD 205
           + + ++ L++  +   ++G + A +  L+ +A  S   F     R   +  Q M   +  
Sbjct: 158 ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPL--QGMLPGLLA 215

Query: 206 VIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENC 265
            ++   G  +          +  D++FLLD S N  + NF Y++ F+   V++LDI  + 
Sbjct: 216 PLRTLSGTPE-------VHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN 268

Query: 266 MRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAY-TGAAIKKLRKEVFSARN 324
           +RVGLV +S+      SL+    KS++L H++ L  + G    TG+A+  +    F+   
Sbjct: 269 IRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAG 328

Query: 325 GSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAE 384
           GSR  + VPQ+ +L+T   SED+  +AA  L R G+  F +G   A+  +LE+IA +P+ 
Sbjct: 329 GSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSL 388

Query: 385 QYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444
            Y+  +  F+ L A  Q  ++ L   ++  V          K         DI  L DGS
Sbjct: 389 VYL--MDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESK--------RDILFLFDGS 438

Query: 445 GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504
            +     F  ++ FL +++   N+ P   R+   QY+D   +E   +++ +K ++   ++
Sbjct: 439 ANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVK 497

Query: 505 NIR-QMGGNTNTGAALNFT--LSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561
            ++ + G   N G AL++      ++ A  +  + V   LV+L  G S D +  PA+ L+
Sbjct: 498 RMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLK 557

Query: 562 EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICT----EEACK 617
           +  +  +    K A+  +L +I      +        + D+  Q+V  + +      A  
Sbjct: 558 QSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV 617

Query: 618 EMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLN 677
             + D++FL+D S  +    F  +K F++ +V    +G DRV++ VVQ+SD  + EF LN
Sbjct: 618 SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 676

Query: 678 RFMSQSDISNAIDQMAHI-GQTTLTGSALSFV-SQYFSPTKGAR--PNIRKFLILITDGE 733
            +M++ D+ NA+ Q+  + G T  TG+AL FV       + G+R    + + LI++T   
Sbjct: 677 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADR 736

Query: 734 AQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVF 793
           + D V+ P+VV+++ G +   +G+  +++T+++ IS  P+    +  F  L  ++  +  
Sbjct: 737 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISE 796

Query: 794 GICS-PREECKRIEVL-------------DVVFVIDSSGSIDYDEYNIMKDFMIGLVKKA 839
            +    REE  R++ +             DVVF+ID S S    E+  ++  +  LV   
Sbjct: 797 RVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL 855

Query: 840 DVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGG-STYTAEALGF-SDH 897
           DVG +  R   ++++DDP+V F L+   +K EV + +Q  +  GG       AL + S +
Sbjct: 856 DVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRN 915

Query: 898 MFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELL 957
           +F    GSR+ +GVPQ L++I+ G+S   D+++  A  L+  G+    +    A+  EL+
Sbjct: 916 IFKRPLGSRIEEGVPQFLVLISSGKSD--DEVDDPAVELKQFGVAPFTIA-RNADQEELV 972

Query: 958 AMAGSSDKYFFVETFGGLKGI 978
            ++ S +  F V TF  L  +
Sbjct: 973 KISLSPEYVFSVSTFRELPSL 993



 Score =  325 bits (833), Expect = 3e-88
 Identities = 246/801 (30%), Positives = 398/801 (49%), Gaps = 51/801 (6%)

Query: 27   DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
            D++FL+D S  +G  +FP+V+ F+  +++SL I  D  RV L Q+SD   +EF L+T++ 
Sbjct: 232  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 291

Query: 87   RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
            +S +L HLR+     G  L  G AL   +  +F+     R ++  P +L++L + +SED+
Sbjct: 292  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 351

Query: 147  VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206
              +A+ AL + G+    VG  +A++  L+ +A +     L  + D S        +I+ +
Sbjct: 352  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQPL 409

Query: 207  IKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM 266
              Y  G V++  V   Q  S  D++FL D S N     F  ++ FL + +  L++K    
Sbjct: 410  TTYVSGGVEE--VPLAQPESKRDILFLFDGSAN-LVGQFPVVRDFLYKIIDELNVKPEGT 466

Query: 267  RVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARNG 325
            R+ +  YS++ KV +      +K E+L  ++ +  +TGKA   G A+   ++ +F    G
Sbjct: 467  RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 526

Query: 326  SRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQ 385
            SR   GV Q  VL+    S D V   A NL++ GV  F    + A   +LE+I   PA  
Sbjct: 527  SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 586

Query: 386  YVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444
              ++ L    DL       LK + N     VS                 E D+  L+DGS
Sbjct: 587  LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDGS 630

Query: 445  GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504
               + + F  +K F+  VV   ++   +VRV  VQY+D    EF +N Y NKQD+  A+ 
Sbjct: 631  EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 689

Query: 505  NIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561
             +  +GG T NTGAAL F L   L+  A  +    VP  L+VLT   S D +  P+  ++
Sbjct: 690  QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVK 749

Query: 562  EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM-- 619
                    IGI  A+ T+++ I+        +  F  L  ++ QV+ E  T+   +E+  
Sbjct: 750  RGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELSR 808

Query: 620  ---------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVV 664
                           K D++FL+D S S GPE F  ++T ++ LV    +G D  ++ V+
Sbjct: 809  LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVI 867

Query: 665  QFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTL-TGSALSFVSQ-YFSPTKGAR--P 720
            QFSD  K EF LN   S+ ++ NA+ ++   G   +  G+AL +VS+  F    G+R   
Sbjct: 868  QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 927

Query: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780
             + +FL+LI+ G++ D V +PAV L+Q GV  +++    ++  +L +IS  PE VF V  
Sbjct: 928  GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVST 986

Query: 781  FDILQRIEDDLVFGICSPREE 801
            F  L  +E  L+  I +   E
Sbjct: 987  FRELPSLEQKLLTPITTLTSE 1007



 Score =  318 bits (816), Expect = 3e-86
 Identities = 221/776 (28%), Positives = 409/776 (52%), Gaps = 39/776 (5%)

Query: 430  VDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFE 489
            ++  + DI  L+DGS +    +F+ ++ F+++V+    I    ++V   QYAD+   EF 
Sbjct: 32   IEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFY 91

Query: 490  INKYSNKQDLGKAIENIRQMGGNT-NTGAALNFTLSLL--QKAKKQRGNKVPCHLVVLTN 546
             N +  K+++  A+  ++ + G+   TG+AL+F  + L    A  +    +P  LV++T 
Sbjct: 92   FNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITG 151

Query: 547  GMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDA--LKDIRN 604
            G S D I +PA  L+   I  +AIG K A+Q +L EIA +   V+   +F A  L+ +  
Sbjct: 152  GKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLP 211

Query: 605  QVVQEICTEEACKEM---KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQI 661
             ++  + T     E+   K DI+FL+D S ++G  NF  ++ F+ NLV+   IG D +++
Sbjct: 212  GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRV 271

Query: 662  GVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTL-TGSALSFV-SQYFSPTKGA- 718
            G+VQFSD    EF LN + ++SDI   + Q+   G + L TGSALS+V + +F+   G+ 
Sbjct: 272  GLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSR 331

Query: 719  -RPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFY 777
             R ++ + L+L+T G+++D   + A  L + G++ + VG   +N  +LE+I+  P +V+ 
Sbjct: 332  IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL 391

Query: 778  VENFDILQRIEDDLVFGICS-----------PREECKRIEVLDVVFVIDSSGSIDYDEYN 826
            +++F  L  +   L+  + +            + E KR    D++F+ D S ++   ++ 
Sbjct: 392  MDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANL-VGQFP 446

Query: 827  IMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST 886
            +++DF+  ++ + +V     R    +Y+DD +V    D+  +K E++++++  +   G  
Sbjct: 447  VVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKA 506

Query: 887  YT-AEALGFSD-HMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVL 944
                 AL ++  ++F ++ GSR+  GV Q L+++  G S  +D+++  A  L+  G++  
Sbjct: 507  LNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPF 564

Query: 945  AVGIDGANPVELLAMAGSSDKYFFVET---FGGLKGIFSDVTASVCNSSKVDCEIDKVDL 1001
                  A+P EL  +  S       E+    G L     ++  SV N +      +K D+
Sbjct: 565  IFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK-DV 623

Query: 1002 VFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEK 1061
            VFL+DGS  ++ + F  +KEF+  VV+  DV  +RVR+   Q+SD   PEF L +++ ++
Sbjct: 624  VFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQ 682

Query: 1062 EISFQIENIKQIFGNT-HIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVA 1119
            ++   +  +  + G T + GAAL  V  +      GSRI  G PQ+L+VLT  +S D+V 
Sbjct: 683  DVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVR 742

Query: 1120 QAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNI 1175
              +  ++  G     +GIG+ D  ++  I+   +  + +  F +L  V + I   +
Sbjct: 743  NPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 798



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 70/365 (19%), Positives = 148/365 (40%), Gaps = 41/365 (11%)

Query: 1752 PVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARH 1811
            P    +++F  D S ++  Q F  +++ +  ++ ++ V+    P G  IA+  Y+   + 
Sbjct: 425  PESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSDDVKV 479

Query: 1812 LVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATF-- 1869
              RF +   K ++L  ++ +  +   A   +G A+ +  R +F ++        +  F  
Sbjct: 480  ESRFDEHQSKPEILNLVKRMKIKTGKA-LNLGYALDYAQRYIFVKSAGSRIEDGVLQFLV 538

Query: 1870 -FSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGAD 1928
               +G+S+D   +   A       ++P +    N          D     Q+++ P+   
Sbjct: 539  LLVAGRSSD--RVDGPASNLKQSGVVPFIFQAKNA---------DPAELEQIVLSPA--- 584

Query: 1929 YIPALERLQRCTFCY-DVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987
            +I A E L +    +  +     S     P PV    D  FLLD S  + S  F  ++ F
Sbjct: 585  FILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSG-FPLLKEF 643

Query: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047
            +  +++  ++  +        RVA++ ++             R EF L +Y +K+ +   
Sbjct: 644  VQRVVESLDVGQDRV------RVAVVQYS----------DRTRPEFYLNSYMNKQDVVNA 687

Query: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107
            V +           G AL++ L N+ +S+   R  + +  +    T+   G+ ++  S+ 
Sbjct: 688  VRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVV 747

Query: 2108 AKCQG 2112
             K  G
Sbjct: 748  VKRGG 752



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%)

Query: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
            G PE   +  +++F LD S +V +  F  +++ +  LV  + +  ++  VG         
Sbjct: 222  GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 272

Query: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856
                 LV+FSD             KS +L  +  +  +  S     G A+ ++  N F  
Sbjct: 273  -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 326

Query: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913
               +    H  ++    ++GQS D++     A+    +    V  + +N   + +  A +
Sbjct: 327  AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 385

Query: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973
             +    ++ +      +PAL +         V         A+P   +S  D  FL D S
Sbjct: 386  PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 438

Query: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033
             N+   +F  +R FL  ++D   + PE      G R+A+  ++            V+ E 
Sbjct: 439  ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 481

Query: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084
                ++SK     L+KR   ++ K LN    +G+AL +    +F+ +   R        +
Sbjct: 482  RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 537

Query: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136
            + +++   +  +DG      +   K  G   F+F      D  ELE +   P
Sbjct: 538  VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 583



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 85/396 (21%), Positives = 153/396 (38%), Gaps = 55/396 (13%)

Query: 1753 VHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHL 1812
            V+  ++VF +D S  +    F  +++ +A +++ +++ ++   V    A+  Y    R  
Sbjct: 34   VNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQV----AVAQYADTVRPE 89

Query: 1813 VRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTL---PGAHTRKIATF 1869
              F+    K +++  +  +     SA    G A+ F+  N+F  +          K+   
Sbjct: 90   FYFNTHPTKREVITAVRKMKPLDGSALYT-GSALDFVRNNLFTSSAGYRAAEGIPKLLVL 148

Query: 1870 FSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQV----IVVPS 1925
             + G+S D   I+  A E     I+              AFAI + G  Q     I   S
Sbjct: 149  ITGGKSLD--EISQPAQELKRSSIM--------------AFAIGNKGADQAELEEIAFDS 192

Query: 1926 GADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIR 1985
               +IPA  R                     P    +  D  FLLD S N+G   F  +R
Sbjct: 193  SLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVR 252

Query: 1986 AFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMK 2045
             F+  L++  +I  +        RV L+  +          +PV  EF+L TY++K  + 
Sbjct: 253  DFVMNLVNSLDIGND------NIRVGLVQFS---------DTPV-TEFSLNTYQTKSDIL 296

Query: 2046 RHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRN----KVIFVISAGETSHLDGEIL 2101
             H+ +   Q       G AL +   N F      R      +++ +++AG++   D  + 
Sbjct: 297  GHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE--DSYLQ 354

Query: 2102 KKESLRAKCQGYALFVFSLGPIWDDK-ELEDLASHP 2136
               +L        +  F +G    +K ELE +A +P
Sbjct: 355  AANALTRA----GILTFCVGASQANKAELEQIAFNP 386



 Score = 35.8 bits (81), Expect = 0.49
 Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 22/162 (13%)

Query: 1742 SPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIA 1801
            SPG  GK        ++VF +D S+     EF+ ++ ++  LV  + V  ++      +A
Sbjct: 818  SPGVGGK-------RDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDT----TRVA 865

Query: 1802 ILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREI--GRAMRFISRNVFKRTLP 1859
            ++ ++   +     +    K ++   ++ +   R    R+I  G A+ ++SRN+FKR L 
Sbjct: 866  VIQFSDDPKVEFLLNAHSSKDEVQNAVQRL---RPKGGRQINVGNALEYVSRNIFKRPLG 922

Query: 1860 GAHTRKIATF---FSSGQSADAHSITTAAMEFGALEIIPVVI 1898
                  +  F    SSG+S D   +   A+E     + P  I
Sbjct: 923  SRIEEGVPQFLVLISSGKSDD--EVDDPAVELKQFGVAPFTI 962


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
            sapiens]
          Length = 1019

 Score =  287 bits (735), Expect = 7e-77
 Identities = 204/644 (31%), Positives = 292/644 (45%), Gaps = 37/644 (5%)

Query: 1398 GDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG---PVGEQGTKGCYGTKGPKGNRGLN 1454
            G  GP G RG  G KG+ G  GE G  G +G PG   P+G  G KG  G KG KG  G +
Sbjct: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 1455 GQEGE---VGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G++G     G+NG DG  G+ G  G PG KG+ G+ G  G PG+ G+PG+RG +G +GDP
Sbjct: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      G  G KG +G QG  G PG PG  G++      G +G  G +G  G  G 
Sbjct: 376  GRPGRRGP-PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G +G  G KG  GP G  G+ GE G  G+KG +G PGP G  G  G  G QG++G+PGD
Sbjct: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLK 1691
             G +G  G PGP+G   + G PG+   G +GA G++G PG  GP+G  GD G  GE G K
Sbjct: 495  AGPRGDSGQPGPKG---DPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 1692 GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPEC 1751
            G +G+    G PGE G  G  G PG +G  G  G    + C+++ YVR+       +  C
Sbjct: 552  GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRC 611

Query: 1752 PVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIK--VRENSCPVGAHIAILSYNSHA 1809
                 ++VF +D S  +    F   K  +  +V  +    ++     G  + ++ Y+   
Sbjct: 612  GA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG 669

Query: 1810 RHLVRFSDAYKKSQLLREIETIP-YERSSASREIGRAMRFISRNVFKRTLPGAHTRKIAT 1868
                   D  +   L    E +   E  +       A++F    + K +     TR  A 
Sbjct: 670  TFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKES-RRQKTRVFAV 728

Query: 1869 FFSSG-----------QSADAHSITTAAMEFGALEIIPVVITFSNVPSVR--RAFAIDDT 1915
              + G           ++     +T  A+  G  ++        N+ S+   +   + + 
Sbjct: 729  VITDGRHDPRDDDLNLRALCDRDVTVTAIGIG--DMFHEKHESENLYSIACDKPQQVRNM 786

Query: 1916 GTFQVIVVPSGADYIPALERLQRCTFCYDV-CKPDASCDQARPPPVQSYMDAAFLLDASR 1974
              F  +V     D +  +        C D+ C+ + S  Q    PV    D  FLLD S 
Sbjct: 787  TLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPV----DIVFLLDGSE 842

Query: 1975 NMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPP 2018
             +G   F   R F+  +     +    +  +   RVALL    P
Sbjct: 843  RLGEQNFHKARRFVEQVARRLTLARRDDDPLNA-RVALLQFGGP 885



 Score =  196 bits (497), Expect = 3e-49
 Identities = 116/270 (42%), Positives = 141/270 (52%), Gaps = 29/270 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G  G PG RGP G+ G  G  GE G  G +G PG  G +G  G  G KG KG 
Sbjct: 336  LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGY 395

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            +         G +G  G  G +G  G PG +G KG+ G +G PG +G+PG  G KG +GD
Sbjct: 396  Q---------GNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD 446

Query: 1511 PGAPGVDSSIEGPTGLKGE---RGRQGRRGWPGPPGTPGSRRKTAAHGRR---GHTGPQG 1564
            PG        EGP GL GE   +G +G RG PGP G  G+  +    G R   G  GP+G
Sbjct: 447  PGP-------EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG 499

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
             +G PGP G  G  G   P GPRG  G KGE       GP+GP G  G+ G +G  G +G
Sbjct: 500  DSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE------PGPRGPEGGRGDFGLKGEPGRKG 552

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPG 1654
             KGEP D G  G  G  GPRG+ G +G PG
Sbjct: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score =  187 bits (474), Expect = 1e-46
 Identities = 107/245 (43%), Positives = 133/245 (54%), Gaps = 23/245 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GDPG PG+RGPPG  G++G    +G  G  GAPG  G +G KG  G +GPKG  
Sbjct: 367  GDQGGKGDPGRPGRRGPPGEIGAKG---SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G  G DG  GE+GD G  G +G  G+ G++G+ G RG PG RG +G  G+P
Sbjct: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G        +G  G  G+ G +G  G PGP G P         GR G + P G  G PG 
Sbjct: 484  GK-------QGSRGDPGDAGPRGDSGQPGPKGDP---------GRPGFSYP-GPRGAPGE 526

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
               +G  G +GP+G RG+ G+KGE G  G KG    PGP GE G +G  G  G +GEPG 
Sbjct: 527  ---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583

Query: 1632 LGEKG 1636
             G+ G
Sbjct: 584  PGDPG 588



 Score =  157 bits (398), Expect = 9e-38
 Identities = 99/243 (40%), Positives = 120/243 (49%), Gaps = 40/243 (16%)

Query: 1520 IEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLG 1579
            I GP+G KG RG++G +G  G PG PG + +    G  G  G  G  G+PG  G +G  G
Sbjct: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313

Query: 1580 LKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPG------------GEAGNQGRLGSQGNKG 1627
              G +G  G AG  G  G  G  G  GPPG              GEAG+ G  G QG KG
Sbjct: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373

Query: 1628 EPGDLGEK---GAVGFPGPRGLQGNDGSPG----------------YGSVGRKGAKGQEG 1668
            +PG  G +   G +G  G +G QGN G+PG                 G  GR+G  G +G
Sbjct: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 1669 FPGESGPKGEIGDPG--GP----GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
             PG  GPKGE GDPG  GP    GE G KGA+G     GLPG  G  G  G PG++G +G
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG---DRGLPGPRGPQGALGEPGKQGSRG 490

Query: 1723 AKG 1725
              G
Sbjct: 491  DPG 493



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 107/434 (24%), Positives = 179/434 (41%), Gaps = 69/434 (15%)

Query: 799  REEC------KRIEVLDVVFVIDSSGSIDYDEYNIMKDFMI------GLVKKADVGKNQV 846
            RE C      KR   LDVVFVIDSS SI Y  + + K+F+I      G + K    +   
Sbjct: 599  RETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGT 658

Query: 847  RFGALKYADDPEV-LFYLDDFGTKLEVIS----VLQNDQAMGGSTYTAEALGFS-DHMFT 900
            R G ++Y+ +       LDD   +++ +S     ++N + + G T+T  AL F+ D +  
Sbjct: 659  RVGVVQYSHEGTFEAIQLDD--ERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK 716

Query: 901  EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGA--------- 951
            E+R  +         +VITDG  HD    +   +AL D+ + V A+GI            
Sbjct: 717  ESRRQKTR----VFAVVITDGR-HDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESEN 771

Query: 952  -------NPVELLAMAGSSDKYFFVETF-GGLKGIFSDVTASVC-------NSSKVDCEI 996
                    P ++  M   SD     E F   ++ +       VC         S   C  
Sbjct: 772  LYSIACDKPQQVRNMTLFSD--LVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQ 829

Query: 997  DKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLN-----RVRIGAAQFSDTYHPE 1051
              VD+VFL+DGS  +   +F K + F+  V +   ++         R+   QF      +
Sbjct: 830  RPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQ 889

Query: 1052 --FPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHYF--RPDMGSRINTGTPQVLL 1107
              FPL   +    I   +E  + +   +H+GA +    +     P  G+R +     V  
Sbjct: 890  VAFPLSHNL--TAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVF- 946

Query: 1108 VLTDG-QSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVH--NFDEL 1164
             LTDG    D + ++A ++R + +    + +G   D  ++      ++    H  ++D L
Sbjct: 947  -LTDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSL 1005

Query: 1165 KKVN--KRIVRNIC 1176
             +     R +R IC
Sbjct: 1006 AQPGFFDRFIRWIC 1019



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 87/399 (21%), Positives = 169/399 (42%), Gaps = 36/399 (9%)

Query: 229  DVVFLLDMSINGSEENFDYLKGFLEESVSALDI------KENCMRVGLVAYSNETKVINS 282
            DVVF++D S +    NF   K F+   V+ L         E   RVG+V YS+E     +
Sbjct: 615  DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG-TFEA 673

Query: 283  LSMGINKSEVL----QHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVL 338
            + +   + + L    + ++NL    G  +T +A+K     +        + Q     AV+
Sbjct: 674  IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK----ESRRQKTRVFAVV 729

Query: 339  VT---HRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAE--QYVSKLKTF 393
            +T   H   +D++   A+  R   VT   +G       + E + S   +  Q V  +  F
Sbjct: 730  ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLF 789

Query: 394  ADLAAHNQTFLKKLRNQITHTVSVFSE----RTETLKSGCVDTEEADIYLLIDGSGSTQA 449
            +DL A  + F+  + + +     +       +TE   + C      DI  L+DGS     
Sbjct: 790  SDLVA--EKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQ-RPVDIVFLLDGSERLGE 846

Query: 450  TDFHEMKTFLSEVVGMFNIA-----PHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504
             +FH+ + F+ +V     +A     P   RV  +Q+    + +       N   + +A+E
Sbjct: 847  QNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALE 906

Query: 505  NIRQMGGNTNTGAALNFTLSLLQKAKKQRGNK-VPCHLVVLTNGMS-KDSILEPANRLRE 562
              + +   ++ GA +   ++ + ++ +    +      V LT+G++  DS+ E A+ +R+
Sbjct: 907  TTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRK 966

Query: 563  EHI--RVYAIGIKEANQTQLREIAGEEKRVYYVHDFDAL 599
            +++   V A+G             G+   V++  D+D+L
Sbjct: 967  QNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSL 1005



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 88/391 (22%), Positives = 165/391 (42%), Gaps = 57/391 (14%)

Query: 607 VQEIC----TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVS---------KSQ 653
           V+E C     E+ C  +  D++F++DSS SIG  NF+  K F+ N+V+         KS+
Sbjct: 598 VRETCGCCDCEKRCGAL--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSE 655

Query: 654 IGPDRVQIGVVQFS-DINKEEFQLN--RFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQ 710
            G    ++GVVQ+S +   E  QL+  R  S S    A+  +  I   T T SAL F   
Sbjct: 656 TG---TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYD 712

Query: 711 YFSPTKGARPNIRKFLILITDGE---AQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEE 767
                +  R   R F ++ITDG      D +   A+  R   V    +G       + E 
Sbjct: 713 RLI-KESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESEN 771

Query: 768 I----SGRPEMVFYVENFD--ILQRIEDDLVFGIC-SPREECKRI-------------EV 807
           +      +P+ V  +  F   + ++  DD+   +C  P+  C  +               
Sbjct: 772 LYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRP 831

Query: 808 LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKN-----QVRFGALKYA--DDPEVL 860
           +D+VF++D S  +    ++  + F+  + ++  + +        R   L++    + +V 
Sbjct: 832 VDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVA 891

Query: 861 FYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITD 920
           F L    T +     L+  Q +   ++    +  + +    +      +      + +TD
Sbjct: 892 FPLSHNLTAIH--EALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTD 949

Query: 921 GESHDADKLNATAKALRDKGIL--VLAVGID 949
           G + + D L+ +A ++R + ++  VLA+G D
Sbjct: 950 GVTGN-DSLHESAHSMRKQNVVPTVLALGSD 979



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 80/387 (20%), Positives = 154/387 (39%), Gaps = 71/387 (18%)

Query: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSL------PIEADKYRVALAQYSDKLHSEFH 80
           DVVF++DSS+ +G  +F   K F+  +++ L      P      RV + QYS       H
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS-------H 667

Query: 81  LSTFKG------RSPMLNHLR---KNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQF 131
             TF+       R   L+  +   KN  +I G      AL+ A+        + R K + 
Sbjct: 668 EGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK--ESRRQKTRV 725

Query: 132 PPILVVLASSESEDNVEEASKALRKDGVKIISVGV-----QKASEENLKAMATSQFHFNL 186
             +++     +  D+ +   +AL    V + ++G+     +K   ENL ++A  +     
Sbjct: 726 FAVVITDGRHDPRDD-DLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK----P 780

Query: 187 RTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSM------------------- 227
           + VR++++FS        D++   E  +DD+    C  P +                   
Sbjct: 781 QQVRNMTLFS--------DLV--AEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQR 830

Query: 228 -ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN-----CMRVGLVAYSNETKVIN 281
             D+VFLLD S    E+NF   + F+E+    L +          RV L+ +    +   
Sbjct: 831 PVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQV 890

Query: 282 SLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTH 341
           +  +  N + + + ++        ++ GA +      +  +  G  +         L   
Sbjct: 891 AFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDG 950

Query: 342 RDSEDNVTKAAVNLRREGV--TIFTLG 366
               D++ ++A ++R++ V  T+  LG
Sbjct: 951 VTGNDSLHESAHSMRKQNVVPTVLALG 977



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 32/156 (20%), Positives = 66/156 (42%), Gaps = 6/156 (3%)

Query: 1750 ECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKV-RENSCPVGAHIAILSYNSH 1808
            +C   P ++VF LD S  + EQ F + +  +  + R + + R +  P+ A +A+L +   
Sbjct: 826  QCTQRPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGP 885

Query: 1809 ARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGA--HTRKI 1866
                V F  ++  + +   +ET  Y  S +   +G  +      + +    GA  H    
Sbjct: 886  GEQQVAFPLSHNLTAIHEALETTQYLNSFS--HVGAGVVHAINAIVRSPRGGARRHAELS 943

Query: 1867 ATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSN 1902
              F + G + +  S+  +A       ++P V+   +
Sbjct: 944  FVFLTDGVTGN-DSLHESAHSMRKQNVVPTVLALGS 978


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
            sapiens]
          Length = 828

 Score =  286 bits (732), Expect = 2e-76
 Identities = 162/417 (38%), Positives = 219/417 (52%), Gaps = 14/417 (3%)

Query: 1398 GDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG---PVGEQGTKGCYGTKGPKGNRGLN 1454
            G  GP G RG  G KG+ G  GE G  G +G PG   P+G  G KG  G KG KG  G +
Sbjct: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 1455 GQEGE---VGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G++G     G+NG DG  G+ G  G PG KG+ G+ G  G PG+ G+PG+RG +G +GDP
Sbjct: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      G  G KG +G QG  G PG PG  G++      G +G  G +G  G  G 
Sbjct: 376  GRPGRRGP-PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G +G  G KG  GP G  G+ GE G  G+KG +G PGP G  G  G  G QG++G+PGD
Sbjct: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLK 1691
             G +G  G PGP+G   + G PG+   G +GA G++G PG  GP+G  GD G  GE G K
Sbjct: 495  AGPRGDSGQPGPKG---DPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 1692 GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPEC 1751
            G +G+    G PGE G  G  G PG +G  G  G    + C+++ YVR+       +  C
Sbjct: 552  GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRC 611

Query: 1752 PVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIK--VRENSCPVGAHIAILSYN 1806
                 ++VF +D S  +    F   K  +  +V  +    ++     G  + ++ Y+
Sbjct: 612  GA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS 666



 Score =  196 bits (497), Expect = 3e-49
 Identities = 116/270 (42%), Positives = 141/270 (52%), Gaps = 29/270 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G  G PG RGP G+ G  G  GE G  G +G PG  G +G  G  G KG KG 
Sbjct: 336  LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGY 395

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            +         G +G  G  G +G  G PG +G KG+ G +G PG +G+PG  G KG +GD
Sbjct: 396  Q---------GNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD 446

Query: 1511 PGAPGVDSSIEGPTGLKGE---RGRQGRRGWPGPPGTPGSRRKTAAHGRR---GHTGPQG 1564
            PG        EGP GL GE   +G +G RG PGP G  G+  +    G R   G  GP+G
Sbjct: 447  PGP-------EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG 499

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
             +G PGP G  G  G   P GPRG  G KGE       GP+GP G  G+ G +G  G +G
Sbjct: 500  DSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE------PGPRGPEGGRGDFGLKGEPGRKG 552

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPG 1654
             KGEP D G  G  G  GPRG+ G +G PG
Sbjct: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score =  187 bits (474), Expect = 1e-46
 Identities = 107/245 (43%), Positives = 133/245 (54%), Gaps = 23/245 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GDPG PG+RGPPG  G++G    +G  G  GAPG  G +G KG  G +GPKG  
Sbjct: 367  GDQGGKGDPGRPGRRGPPGEIGAKG---SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G  G DG  GE+GD G  G +G  G+ G++G+ G RG PG RG +G  G+P
Sbjct: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G        +G  G  G+ G +G  G PGP G P         GR G + P G  G PG 
Sbjct: 484  GK-------QGSRGDPGDAGPRGDSGQPGPKGDP---------GRPGFSYP-GPRGAPGE 526

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
               +G  G +GP+G RG+ G+KGE G  G KG    PGP GE G +G  G  G +GEPG 
Sbjct: 527  ---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583

Query: 1632 LGEKG 1636
             G+ G
Sbjct: 584  PGDPG 588



 Score =  157 bits (398), Expect = 9e-38
 Identities = 99/243 (40%), Positives = 120/243 (49%), Gaps = 40/243 (16%)

Query: 1520 IEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLG 1579
            I GP+G KG RG++G +G  G PG PG + +    G  G  G  G  G+PG  G +G  G
Sbjct: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313

Query: 1580 LKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPG------------GEAGNQGRLGSQGNKG 1627
              G +G  G AG  G  G  G  G  GPPG              GEAG+ G  G QG KG
Sbjct: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373

Query: 1628 EPGDLGEK---GAVGFPGPRGLQGNDGSPG----------------YGSVGRKGAKGQEG 1668
            +PG  G +   G +G  G +G QGN G+PG                 G  GR+G  G +G
Sbjct: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 1669 FPGESGPKGEIGDPG--GP----GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
             PG  GPKGE GDPG  GP    GE G KGA+G     GLPG  G  G  G PG++G +G
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG---DRGLPGPRGPQGALGEPGKQGSRG 490

Query: 1723 AKG 1725
              G
Sbjct: 491  DPG 493



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 54/168 (32%), Positives = 83/168 (49%), Gaps = 25/168 (14%)

Query: 799 REEC------KRIEVLDVVFVIDSSGSIDYDEYNIMKDFMI------GLVKKADVGKNQV 846
           RE C      KR   LDVVFVIDSS SI Y  + + K+F+I      G + K    +   
Sbjct: 599 RETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGT 658

Query: 847 RFGALKYADDPEV-LFYLDDFGTKLEVIS----VLQNDQAMGGSTYTAEALGFS-DHMFT 900
           R G ++Y+ +       LDD   +++ +S     ++N + + G T+T  AL F+ D +  
Sbjct: 659 RVGVVQYSHEGTFEAIQLDD--ERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK 716

Query: 901 EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGI 948
           E+R  +         +VITDG  HD    +   +AL D+ + V A+GI
Sbjct: 717 ESRRQKTR----VFAVVITDGR-HDPRDDDLNLRALCDRDVTVTAIGI 759



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 22/142 (15%)

Query: 607 VQEIC----TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVS---------KSQ 653
           V+E C     E+ C  +  D++F++DSS SIG  NF+  K F+ N+V+         KS+
Sbjct: 598 VRETCGCCDCEKRCGAL--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSE 655

Query: 654 IGPDRVQIGVVQFS-DINKEEFQLN--RFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQ 710
            G    ++GVVQ+S +   E  QL+  R  S S    A+  +  I   T T SAL F   
Sbjct: 656 TG---TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYD 712

Query: 711 YFSPTKGARPNIRKFLILITDG 732
                +  R   R F ++ITDG
Sbjct: 713 RLI-KESRRQKTRVFAVVITDG 733



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 46/160 (28%), Positives = 68/160 (42%), Gaps = 18/160 (11%)

Query: 428 GCVDTEEA----DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNI------APHKVRVGA 477
           GC D E+     D+  +ID S S   T+F   K F+  VV           +    RVG 
Sbjct: 603 GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662

Query: 478 VQYADSWDLE---FEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRG 534
           VQY+     E    +  +  +     +A++N+  + G T T +AL F    L   K+ R 
Sbjct: 663 VQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRL--IKESRR 720

Query: 535 NKVPCHLVVLTNGM--SKDSILEPANRLREEHIRVYAIGI 572
            K     VV+T+G    +D  L     L +  + V AIGI
Sbjct: 721 QKTRVFAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGI 759



 Score = 38.5 bits (88), Expect = 0.076
 Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 34/190 (17%)

Query: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSL------PIEADKYRVALAQYSDKLHSEFH 80
           DVVF++DSS+ +G  +F   K F+  +++ L      P      RV + QYS       H
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS-------H 667

Query: 81  LSTFKG------RSPMLNHLR---KNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQF 131
             TF+       R   L+  +   KN  +I G      AL+ A+        + R K + 
Sbjct: 668 EGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK--ESRRQKTRV 725

Query: 132 PPILVVLASSESEDNVEEASKALRKDGVKIISVGV-----QKASEENLKAMATSQFHFNL 186
             +++     +  D+ +   +AL    V + ++G+     +K   ENL ++A  +     
Sbjct: 726 FAVVITDGRHDPRDD-DLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK----P 780

Query: 187 RTVRDLSMFS 196
           + VR++++FS
Sbjct: 781 QQVRNMTLFS 790



 Score = 37.4 bits (85), Expect = 0.17
 Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 29/167 (17%)

Query: 993  DCE--IDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDV------SLNRVRIGAAQF 1044
            DCE     +D+VF++D S SI   +F   K F+ +VV           S    R+G  Q+
Sbjct: 606  DCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQY 665

Query: 1045 SDTYHPEFPLGTF----IGEKEI----SFQ--IENIKQIFGNTHIGAALREVEHYFRPDM 1094
            S         GTF    + ++ I    SF+  ++N++ I G T   +AL+    Y R   
Sbjct: 666  SHE-------GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA--YDRLIK 716

Query: 1095 GSRINTGTPQVLLVLTDGQSQDEVAQA-AEALRHRGIDIYSVGIGDV 1140
             SR    T    +V+TDG+           AL  R + + ++GIGD+
Sbjct: 717  ESR-RQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDM 762



 Score = 35.4 bits (80), Expect = 0.64
 Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 20/185 (10%)

Query: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDI------KENCMRVGLVAYSNETKVINS 282
           DVVF++D S +    NF   K F+   V+ L         E   RVG+V YS+E     +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE-GTFEA 673

Query: 283 LSMGINKSEVL----QHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVL 338
           + +   + + L    + ++NL    G  +T +A+K     +        + Q     AV+
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK----ESRRQKTRVFAVV 729

Query: 339 VT---HRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAE--QYVSKLKTF 393
           +T   H   +D++   A+  R   VT   +G       + E + S   +  Q V  +  F
Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLF 789

Query: 394 ADLAA 398
           +DL A
Sbjct: 790 SDLVA 794


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
            sapiens]
          Length = 918

 Score =  286 bits (732), Expect = 2e-76
 Identities = 162/417 (38%), Positives = 219/417 (52%), Gaps = 14/417 (3%)

Query: 1398 GDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG---PVGEQGTKGCYGTKGPKGNRGLN 1454
            G  GP G RG  G KG+ G  GE G  G +G PG   P+G  G KG  G KG KG  G +
Sbjct: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 1455 GQEGE---VGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G++G     G+NG DG  G+ G  G PG KG+ G+ G  G PG+ G+PG+RG +G +GDP
Sbjct: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      G  G KG +G QG  G PG PG  G++      G +G  G +G  G  G 
Sbjct: 376  GRPGRRGP-PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G +G  G KG  GP G  G+ GE G  G+KG +G PGP G  G  G  G QG++G+PGD
Sbjct: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLK 1691
             G +G  G PGP+G   + G PG+   G +GA G++G PG  GP+G  GD G  GE G K
Sbjct: 495  AGPRGDSGQPGPKG---DPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 1692 GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPEC 1751
            G +G+    G PGE G  G  G PG +G  G  G    + C+++ YVR+       +  C
Sbjct: 552  GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRC 611

Query: 1752 PVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIK--VRENSCPVGAHIAILSYN 1806
                 ++VF +D S  +    F   K  +  +V  +    ++     G  + ++ Y+
Sbjct: 612  GA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS 666



 Score =  196 bits (497), Expect = 3e-49
 Identities = 116/270 (42%), Positives = 141/270 (52%), Gaps = 29/270 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G  G PG RGP G+ G  G  GE G  G +G PG  G +G  G  G KG KG 
Sbjct: 336  LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGY 395

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            +         G +G  G  G +G  G PG +G KG+ G +G PG +G+PG  G KG +GD
Sbjct: 396  Q---------GNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD 446

Query: 1511 PGAPGVDSSIEGPTGLKGE---RGRQGRRGWPGPPGTPGSRRKTAAHGRR---GHTGPQG 1564
            PG        EGP GL GE   +G +G RG PGP G  G+  +    G R   G  GP+G
Sbjct: 447  PGP-------EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG 499

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
             +G PGP G  G  G   P GPRG  G KGE       GP+GP G  G+ G +G  G +G
Sbjct: 500  DSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE------PGPRGPEGGRGDFGLKGEPGRKG 552

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPG 1654
             KGEP D G  G  G  GPRG+ G +G PG
Sbjct: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score =  187 bits (474), Expect = 1e-46
 Identities = 107/245 (43%), Positives = 133/245 (54%), Gaps = 23/245 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GDPG PG+RGPPG  G++G    +G  G  GAPG  G +G KG  G +GPKG  
Sbjct: 367  GDQGGKGDPGRPGRRGPPGEIGAKG---SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G  G DG  GE+GD G  G +G  G+ G++G+ G RG PG RG +G  G+P
Sbjct: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G        +G  G  G+ G +G  G PGP G P         GR G + P G  G PG 
Sbjct: 484  GK-------QGSRGDPGDAGPRGDSGQPGPKGDP---------GRPGFSYP-GPRGAPGE 526

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
               +G  G +GP+G RG+ G+KGE G  G KG    PGP GE G +G  G  G +GEPG 
Sbjct: 527  ---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583

Query: 1632 LGEKG 1636
             G+ G
Sbjct: 584  PGDPG 588



 Score =  157 bits (398), Expect = 9e-38
 Identities = 99/243 (40%), Positives = 120/243 (49%), Gaps = 40/243 (16%)

Query: 1520 IEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLG 1579
            I GP+G KG RG++G +G  G PG PG + +    G  G  G  G  G+PG  G +G  G
Sbjct: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313

Query: 1580 LKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPG------------GEAGNQGRLGSQGNKG 1627
              G +G  G AG  G  G  G  G  GPPG              GEAG+ G  G QG KG
Sbjct: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373

Query: 1628 EPGDLGEK---GAVGFPGPRGLQGNDGSPG----------------YGSVGRKGAKGQEG 1668
            +PG  G +   G +G  G +G QGN G+PG                 G  GR+G  G +G
Sbjct: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 1669 FPGESGPKGEIGDPG--GP----GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
             PG  GPKGE GDPG  GP    GE G KGA+G     GLPG  G  G  G PG++G +G
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG---DRGLPGPRGPQGALGEPGKQGSRG 490

Query: 1723 AKG 1725
              G
Sbjct: 491  DPG 493



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 54/168 (32%), Positives = 83/168 (49%), Gaps = 25/168 (14%)

Query: 799 REEC------KRIEVLDVVFVIDSSGSIDYDEYNIMKDFMI------GLVKKADVGKNQV 846
           RE C      KR   LDVVFVIDSS SI Y  + + K+F+I      G + K    +   
Sbjct: 599 RETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGT 658

Query: 847 RFGALKYADDPEV-LFYLDDFGTKLEVIS----VLQNDQAMGGSTYTAEALGFS-DHMFT 900
           R G ++Y+ +       LDD   +++ +S     ++N + + G T+T  AL F+ D +  
Sbjct: 659 RVGVVQYSHEGTFEAIQLDD--ERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK 716

Query: 901 EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGI 948
           E+R  +         +VITDG  HD    +   +AL D+ + V A+GI
Sbjct: 717 ESRRQKTR----VFAVVITDGR-HDPRDDDLNLRALCDRDVTVTAIGI 759



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 22/142 (15%)

Query: 607 VQEIC----TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVS---------KSQ 653
           V+E C     E+ C  +  D++F++DSS SIG  NF+  K F+ N+V+         KS+
Sbjct: 598 VRETCGCCDCEKRCGAL--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSE 655

Query: 654 IGPDRVQIGVVQFS-DINKEEFQLN--RFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQ 710
            G    ++GVVQ+S +   E  QL+  R  S S    A+  +  I   T T SAL F   
Sbjct: 656 TG---TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYD 712

Query: 711 YFSPTKGARPNIRKFLILITDG 732
                +  R   R F ++ITDG
Sbjct: 713 RLI-KESRRQKTRVFAVVITDG 733



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 46/160 (28%), Positives = 68/160 (42%), Gaps = 18/160 (11%)

Query: 428 GCVDTEEA----DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNI------APHKVRVGA 477
           GC D E+     D+  +ID S S   T+F   K F+  VV           +    RVG 
Sbjct: 603 GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662

Query: 478 VQYADSWDLE---FEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRG 534
           VQY+     E    +  +  +     +A++N+  + G T T +AL F    L   K+ R 
Sbjct: 663 VQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRL--IKESRR 720

Query: 535 NKVPCHLVVLTNGM--SKDSILEPANRLREEHIRVYAIGI 572
            K     VV+T+G    +D  L     L +  + V AIGI
Sbjct: 721 QKTRVFAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGI 759



 Score = 38.9 bits (89), Expect = 0.058
 Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 46/245 (18%)

Query: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSL------PIEADKYRVALAQYSDKLHSEFH 80
           DVVF++DSS+ +G  +F   K F+  +++ L      P      RV + QYS       H
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS-------H 667

Query: 81  LSTFKG------RSPMLNHLR---KNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQF 131
             TF+       R   L+  +   KN  +I G      AL+ A+        + R K + 
Sbjct: 668 EGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK--ESRRQKTRV 725

Query: 132 PPILVVLASSESEDNVEEASKALRKDGVKIISVGV-----QKASEENLKAMATSQFHFNL 186
             +++     +  D+ +   +AL    V + ++G+     +K   ENL ++A  +     
Sbjct: 726 FAVVITDGRHDPRDD-DLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK----P 780

Query: 187 RTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMA--DVVFLLDMSINGSEEN 244
           + VR++++FS        D++   E  +DD+    C  P +   D+    D    G E  
Sbjct: 781 QQVRNMTLFS--------DLV--AEKFIDDMEDVLCPDPQIVCPDLPCQTDAPWPGGEPP 830

Query: 245 FDYLK 249
             +L+
Sbjct: 831 VTFLR 835



 Score = 37.4 bits (85), Expect = 0.17
 Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 29/167 (17%)

Query: 993  DCE--IDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDV------SLNRVRIGAAQF 1044
            DCE     +D+VF++D S SI   +F   K F+ +VV           S    R+G  Q+
Sbjct: 606  DCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQY 665

Query: 1045 SDTYHPEFPLGTF----IGEKEI----SFQ--IENIKQIFGNTHIGAALREVEHYFRPDM 1094
            S         GTF    + ++ I    SF+  ++N++ I G T   +AL+    Y R   
Sbjct: 666  SHE-------GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA--YDRLIK 716

Query: 1095 GSRINTGTPQVLLVLTDGQSQDEVAQA-AEALRHRGIDIYSVGIGDV 1140
             SR    T    +V+TDG+           AL  R + + ++GIGD+
Sbjct: 717  ESR-RQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDM 762



 Score = 35.4 bits (80), Expect = 0.64
 Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 20/185 (10%)

Query: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDI------KENCMRVGLVAYSNETKVINS 282
           DVVF++D S +    NF   K F+   V+ L         E   RVG+V YS+E     +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE-GTFEA 673

Query: 283 LSMGINKSEVL----QHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVL 338
           + +   + + L    + ++NL    G  +T +A+K     +        + Q     AV+
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK----ESRRQKTRVFAVV 729

Query: 339 VT---HRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAE--QYVSKLKTF 393
           +T   H   +D++   A+  R   VT   +G       + E + S   +  Q V  +  F
Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLF 789

Query: 394 ADLAA 398
           +DL A
Sbjct: 790 SDLVA 794


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score =  283 bits (725), Expect = 1e-75
 Identities = 236/800 (29%), Positives = 350/800 (43%), Gaps = 66/800 (8%)

Query: 1377 NVAERTCCCLFCK-CIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE 1435
            N  E+ CC   C+   G  G  GDPG  G+RG PG  G +G  G+ G  G+ G  G  G 
Sbjct: 241  NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK 1495
            +G KG  G KG +G +G  G++G+ G +G+DG+ GE G  GLPG KG  G +G QG PG 
Sbjct: 301  KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360

Query: 1496 RGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG 1555
            +G PG  G KG +G+PGA       +G  G  G  G  G  G PG PG PG + +    G
Sbjct: 361  KGDPGAFGLKGEKGEPGA-------DGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG 413

Query: 1556 RRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAG 1615
              G  G  G  G PG  G  G+ G +GP+G  GEAG +G++G    +GP G PG  GEAG
Sbjct: 414  NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG---REGPVGVPGDPGEAG 470

Query: 1616 NQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGP 1675
              G  G +G++G PG    +GA G PGP G  G+ G  G          G EGFPG  G 
Sbjct: 471  PIGPKGYRGDEGPPGS---EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGY 527

Query: 1676 KGEIGDPGGPGETGLKGARGKMISAGLPGE----------MGSPGEPGPPGRKGVKGAKG 1725
             G  G PG  G  G  G +G    AG PG+           G+ G  GP G +G  G +G
Sbjct: 528  PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQG 587

Query: 1726 LASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLV- 1784
                  CE++  +           EC   P +L+F LD S  +  Q FE  K+ +  ++ 
Sbjct: 588  PPGPDECEILDIIMKMC----SCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVID 643

Query: 1785 ---RDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLRE-IETIPYERSSASR 1840
               RD  V+       A +   S++    H+   S + +  Q L+E I+++ +   +   
Sbjct: 644  RLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQW--MAGGT 701

Query: 1841 EIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTA--AMEFGALEIIPVVI 1898
              G A+++       + LP +   +IA   + G+S D    TT    +    ++++ V I
Sbjct: 702  FTGEALQYTR----DQLLPPSPNNRIALVITDGRS-DTQRDTTPLNVLCSPGIQVVSVGI 756

Query: 1899 --TFSNVPSVRRAFAIDDTGTFQVIVVPS----GADYIPALER--LQRCT--FCYDVCKP 1948
               F  +P   +   I   G       P       +Y   LE   L+  T   C D   P
Sbjct: 757  KDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCP 816

Query: 1949 DASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGD 2008
            D +C    P    S  D   LLD S ++GS  F+  + F   L + F +T          
Sbjct: 817  DYTC----PITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERF-LTAGRTDPAHDV 871

Query: 2009 RVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWT 2068
            RVA++ ++        Q+ P RA      +           +++  +N    +  AL + 
Sbjct: 872  RVAVVQYS-----GTGQQRPERASLQ---FLQNYTALASAVDAMDFINDATDVNDALGY- 922

Query: 2069 LDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKE 2128
            +   +    +    K + + S G +       ++K    A+  G  +FV  +G   ++  
Sbjct: 923  VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPH 982

Query: 2129 LEDLASHPLDHHLVQLGRIH 2148
            +  L +     + V  G  H
Sbjct: 983  IRVLVTGKTAEYDVAYGESH 1002



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 98/374 (26%), Positives = 160/374 (42%), Gaps = 53/374 (14%)

Query: 436 DIYLLIDGSGSTQATDFHEMKTFLSEVVG------MFNIAPHKVRVGAVQYADSWDLE-- 487
           D+  ++D S S    +F   K F+ +V+       +    P +   G VQY+ S   E  
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 488 -FEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTN 546
                   N Q+L +AI++++ M G T TG AL +T    Q       N++    +V+T+
Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRD--QLLPPSPNNRI---ALVITD 729

Query: 547 GMS-KDSILEPANRLREEHIRVYAIGIKEA----------NQTQLREIAGEEKR----VY 591
           G S       P N L    I+V ++GIK+           N    + +A  + R    + 
Sbjct: 730 GRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLV 789

Query: 592 YVHDFDALKD-IRNQVVQEICTEEACKE--------MKADIMFLVDSSGSIGPENFSKMK 642
             +  + L+D     V  +IC ++ C +          ADI  L+D S S+G  NF   K
Sbjct: 790 KENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTK 849

Query: 643 TFMKNLVSK----SQIGPDR-VQIGVVQFSDINK---EEFQLNRFMSQSDISNAIDQMAH 694
            F K L  +     +  P   V++ VVQ+S   +   E   L    + + +++A+D M  
Sbjct: 850 RFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDF 909

Query: 695 IGQTTLTGSALSFVSQYF-SPTKGARPNIRKFLILITDGEAQDIVK---EPAVVLRQEGV 750
           I   T    AL +V++++   + GA    +K L+L +DG +Q       E AV   Q   
Sbjct: 910 INDATDVNDALGYVTRFYREASSGA---AKKRLLLFSDGNSQGATPAAIEKAVQEAQRAG 966

Query: 751 IIYSVGVFGSNVTQ 764
           I   V V G  V +
Sbjct: 967 IEIFVVVVGRQVNE 980



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 98/407 (24%), Positives = 172/407 (42%), Gaps = 57/407 (14%)

Query: 790  DLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGK------ 843
            D++  +CS  E CK    +D++FV+DSS SI    + I KDF++ ++ +    +      
Sbjct: 598  DIIMKMCSCCE-CK-CGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEP 655

Query: 844  NQVRFGALKYADDP---EVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMF 899
             Q   G ++Y+       V           E+   +++ Q M G T+T EAL ++ D + 
Sbjct: 656  GQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLL 715

Query: 900  TEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGI----------D 949
              +  +R       + +VITDG S D  +       L   GI V++VGI          D
Sbjct: 716  PPSPNNR-------IALVITDGRS-DTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSD 767

Query: 950  GANPVELLAMAGSSDK---YFFVETFGGL--KGIFSDVTASVCNSSKVD---CEI---DK 998
              N +    +A S  +       E +  L       +VTA +C   K     C I     
Sbjct: 768  QLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSP 827

Query: 999  VDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVS-----LNRVRIGAAQFSDT--YHPE 1051
             D+  L+DGS S+  ++F   K F   + + F  +      + VR+   Q+S T    PE
Sbjct: 828  ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887

Query: 1052 FPLGTFI-GEKEISFQIENIKQIFGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLT 1110
                 F+     ++  ++ +  I   T +  AL  V  ++R       +    + LL+ +
Sbjct: 888  RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYR----EASSGAAKKRLLLFS 943

Query: 1111 DGQSQD----EVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAE 1153
            DG SQ      + +A +  +  GI+I+ V +G   ++  I++  T +
Sbjct: 944  DGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGK 990



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 95/409 (23%), Positives = 167/409 (40%), Gaps = 61/409 (14%)

Query: 606 VVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSK------SQIGPDRV 659
           ++ ++C+   CK    D++F++DSS SIG +NF   K F+  ++ +       +  P + 
Sbjct: 599 IIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS 658

Query: 660 QIGVVQFSDINKEEFQLNR---FMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTK 716
             GVVQ+S    +E    R     +  ++  AI  +  +   T TG AL +      P  
Sbjct: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718

Query: 717 GARPNIRKFLILITDGEAQDIVKE--PAVVLRQEGVIIYSVGV-----FGSNVTQLEEIS 769
              PN  +  ++ITDG + D  ++  P  VL   G+ + SVG+     F     QL  IS
Sbjct: 719 ---PN-NRIALVITDGRS-DTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVIS 773

Query: 770 --------GRPEMVFYVENF------DILQRIEDDLVFGICSPREECKRI--EVLDVVFV 813
                   GRP +    EN+        L+ +   +      P   C        D+  +
Sbjct: 774 CQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITIL 833

Query: 814 IDSSGSIDYDEYNIMKDFMIGLVKK-ADVGK----NQVRFGALKYA----DDPE--VLFY 862
           +D S S+    ++  K F   L ++    G+    + VR   ++Y+      PE   L +
Sbjct: 834 LDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQF 893

Query: 863 LDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITDGE 922
           L ++      +  +     +  +T   +ALG+    + EA      K     L++ +DG 
Sbjct: 894 LQNYTALASAVDAM---DFINDATDVNDALGYVTRFYREASSGAAKKR----LLLFSDGN 946

Query: 923 SHDADKLNATAKALRDK-----GILVLAVGIDGANPVELLAMAGSSDKY 966
           S  A    A  KA+++       I V+ VG     P   + + G + +Y
Sbjct: 947 SQGATPA-AIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEY 994



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 96/439 (21%), Positives = 174/439 (39%), Gaps = 79/439 (17%)

Query: 216  DIFVEACQ------GPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKE------ 263
            DI ++ C       GP   D++F+LD S +   +NF+  K F+ + +  L   E      
Sbjct: 598  DIIMKMCSCCECKCGP--IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEP 655

Query: 264  NCMRVGLVAYSNET--KVINSLSMGI-NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVF 320
                 G+V YS+    + ++  S  I N  E+ + I++L    G  +TG A++  R ++ 
Sbjct: 656  GQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLL 715

Query: 321  SARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVN-LRREGVTIFTLGIEGASD------- 372
                 +R       IA+++T   S+       +N L   G+ + ++GI+   D       
Sbjct: 716  PPSPNNR-------IALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQ 768

Query: 373  ---TQLEKIASHPAEQYVSKLK-TFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSG 428
                  + +A       +S +K  +A+L      FLK +  QI        ++       
Sbjct: 769  LNVISCQGLAPSQGRPGLSLVKENYAELL--EDAFLKNVTAQIC-----IDKKCPDYTCP 821

Query: 429  CVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIA-----PHKVRVGAVQYADS 483
               +  ADI +L+DGS S  + +F   K F   +   F  A      H VRV  VQY+ +
Sbjct: 822  ITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGT 881

Query: 484  WDLEFE---INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCH 540
                 E   +    N   L  A++ +  +   T+   AL +     ++A      K    
Sbjct: 882  GQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKK---R 938

Query: 541  LVVLTNGMSKDS--------------------ILEPANRLREEHIRVYAIGIKEANQTQL 580
            L++ ++G S+ +                    ++    ++ E HIRV   G     +T  
Sbjct: 939  LLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTG-----KTAE 993

Query: 581  REIAGEEKRVYYVHDFDAL 599
             ++A  E  ++ V  + AL
Sbjct: 994  YDVAYGESHLFRVPSYQAL 1012



 Score = 32.7 bits (73), Expect = 4.2
 Identities = 37/163 (22%), Positives = 69/163 (42%), Gaps = 21/163 (12%)

Query: 615 ACKEMKADIMFLVDSSGSIGPEN------FSKMKTFMKNLVSKSQIGPDRVQ------IG 662
           A ++   D+ F++D+S S+            K+K+F K  +   +    R         G
Sbjct: 30  AFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAG 89

Query: 663 VVQFSDINKEEFQLNRFMSQSD-ISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPN 721
            + +SD  +    L R     D + +++D + + G+ T T  A+    +      G+   
Sbjct: 90  ALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLL-VGGSHLK 148

Query: 722 IRKFLILITDGEAQDIVKEPAVVL-------RQEGVIIYSVGV 757
             K+LI++TDG   +  KEP   L       +  GV ++SV +
Sbjct: 149 ENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAI 191



 Score = 32.7 bits (73), Expect = 4.2
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 17/168 (10%)

Query: 26  ADVVFLVDSSDRLGSKSFPFVKMFITK-----MISSLPIEADKYRVALAQYS--DKLHSE 78
           AD+  L+D S  +GS +F   K F  +     + +     A   RVA+ QYS   +   E
Sbjct: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887

Query: 79  FHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVL 138
                F      L        FI  +  +  AL    R Y  A +    K+     L++ 
Sbjct: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKR-----LLLF 942

Query: 139 ASSESED----NVEEASKALRKDGVKIISVGV-QKASEENLKAMATSQ 181
           +   S+      +E+A +  ++ G++I  V V ++ +E +++ + T +
Sbjct: 943 SDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGK 990


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  282 bits (721), Expect = 3e-75
 Identities = 163/374 (43%), Positives = 192/374 (51%), Gaps = 41/374 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQG---TKGCYGTKGPK 1448
            G  G  G  GP G  GPPG  G +G  G+ G AGERG PGP G +G   T G  G KG +
Sbjct: 231  GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 290

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG---------------DEGSQGSP 1493
            G  GL+G +GE G  G+ G +G  G+NG PG  G +G                 G+ G P
Sbjct: 291  GYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQP 350

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAA 1553
            G  G PG  G  G  G PGAPG      GPTG +G  G QG RG PG PG+PG    +  
Sbjct: 351  GPAGPPGPVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409

Query: 1554 HGRRGHTGPQGTAG---------IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
             G  G  G +G+AG          PGP G  G  G  GP GP+G+ G  G  G  G +GP
Sbjct: 410  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 469

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGA 1663
            +G PGP G  G  G  G +G +G  G+ G  G +G PG RG  GN G PG  G  G KGA
Sbjct: 470  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529

Query: 1664 KGQEGFPGESGPKGEIGDPGGPGETGLKGAR------------GKMISAGLPGEMGSPGE 1711
             G+ G  G +GPKG  GDPG PGE GL GAR            GK+  +G PGE G PG 
Sbjct: 530  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 1712 PGPPGRKGVKGAKG 1725
            PGP G +G  G  G
Sbjct: 590  PGPQGARGQPGVMG 603



 Score =  269 bits (687), Expect = 3e-71
 Identities = 159/377 (42%), Positives = 186/377 (49%), Gaps = 27/377 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GD G PG +GP G  G +G  G  G  G RGA GP G  G  G  G  GP G+ 
Sbjct: 852  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSN 911

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G +G DG  G +GD+G PGR GE G +G  G PG++G PGD G  G  G P
Sbjct: 912  GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 971

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G  G+     G  GL G+RG +G  G PGP G PG +    A G RG  GP G  G+ GP
Sbjct: 972  GPQGLAGQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030

Query: 1572 ---DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
                G EGS G  GP G  G AGVKG++G  G+ G  G PGP G  G  G  G QG++GE
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGF------PGESGPKGE 1678
             G  G  G  G  G RG+QG  G  G     G  G +G KG  GF      PG  GP G+
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 1679 IGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYV 1738
             G  G  G +G +G  G +  +G  G  G PG  GPPG +G  G  G A           
Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG---------- 1200

Query: 1739 RDRSPGRHGKPECPVHP 1755
                PG  G P  P  P
Sbjct: 1201 ---PPGNPGPPGPPGPP 1214



 Score =  266 bits (679), Expect = 2e-70
 Identities = 151/342 (44%), Positives = 177/342 (51%), Gaps = 13/342 (3%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT G  GP G  GP G  G++G  G +G+ GERGA G  G +G +G  G KGP+G  
Sbjct: 720  GLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 779

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G +G  G  G  G  G  G  G+ G  G  G  G  G++G+PG+RG  G  G  G  G P
Sbjct: 780  GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839

Query: 1512 GAPGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
            GA G   +   +G  G KG+ G  G +G  G PG  G    T   G RG  GP G  G P
Sbjct: 840  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899

Query: 1570 GPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEP 1629
            G  G  G  G  G  GP G  G  G+ G  G++G  GPPG  GE G QG  G  G KGEP
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 1630 GDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETG 1689
            GD G  GA G PGP+GL G       G VG  G +G+ GFPG  GP GE G  G PG +G
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQ-----RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 1014

Query: 1690 LKGARGKMISAGL------PGEMGSPGEPGPPGRKGVKGAKG 1725
             +G  G +   GL      PG  GSPG  GPPGR G  G KG
Sbjct: 1015 DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056



 Score =  262 bits (669), Expect = 3e-69
 Identities = 159/379 (41%), Positives = 188/379 (49%), Gaps = 50/379 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG  G++G PG  G  G  G++G  G  G PGP G  G +G  G  GP G +
Sbjct: 606  GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G  G  GE G  G  G  G+ G PG  G +G+   +G PG+RG+PG +G +G RG P
Sbjct: 666  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE---RGFPGERGSPGAQGLQGPRGLP 722

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG D    GP G  G  G  G +G PG  G PG R      G +G  G  G  G  G 
Sbjct: 723  GTPGTD----GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP---------------QGPPGPGGEAGN 1616
             G +G  GL GP GP G AG  GEKG VG  GP                GPPGP G AG 
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGES-- 1673
             G  G  G KGE G+ G+KG  G PGP+G  G  G  G  G  G KGA+G +G PG +  
Sbjct: 839  PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGF 898

Query: 1674 -------GPKGEIGDPGGP------GETGLKGARGK------------MISAGLPGEMGS 1708
                   GP G  G+PG P      G+ G KGARG                AG PGE G 
Sbjct: 899  PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 958

Query: 1709 PGEPGPPGRKGVKGAKGLA 1727
            PG+ GP G +G  G +GLA
Sbjct: 959  PGDDGPSGAEGPPGPQGLA 977



 Score =  261 bits (667), Expect = 6e-69
 Identities = 167/405 (41%), Positives = 201/405 (49%), Gaps = 44/405 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAG----ERGAP-----GPVGEQGTKGCY 1442
            G  GT G+PGPPG  GPPG  G  G    +   G      GA      GP+G  G +G  
Sbjct: 153  GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  G  G +G  G  GE GE G+ G  G +G  G PG+ G+ G+ G  G  G+RG PG +
Sbjct: 213  GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 1503 GAKGLRGDPGAPGVD-----------SSIEGPTGLKGERGRQGRRGWP---GPPGTPGSR 1548
            GA+G  G PG PGV                G  G+KGE G  G  G P   GP G PG R
Sbjct: 273  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 1549 RKT---AAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQ 1605
             +T    A G RG+ G  G AG PGP G  G  G  G  G +GEAG  G +G  G++GP+
Sbjct: 333  GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392

Query: 1606 ------GPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSV 1658
                  G PGP G +GN G  G  G KG  G  G  GA GFPGPRG  G  G+ G  G  
Sbjct: 393  GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452

Query: 1659 GRKGAKGQEGFPGESGPKGEIGD------PGGPGETGLKGARGK---MISAGLPGEMGSP 1709
            G+ G  G  GF GE GPKGE G       PG  GE G +GARG+   +   G PGE G+P
Sbjct: 453  GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP 512

Query: 1710 GEPGPPGRKGVKGAKGLASFSTCELIQYVR--DRSPGRHGKPECP 1752
            G  G PG+ G+ G KG         +   +  +  PGR G+P  P
Sbjct: 513  GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557



 Score =  261 bits (667), Expect = 6e-69
 Identities = 158/365 (43%), Positives = 185/365 (50%), Gaps = 35/365 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG----- 1446
            G  G +G  G  G+ G  GFKG +G  GE G AG +GAPGP GE+G +G  G  G     
Sbjct: 444  GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 1447 -PKGNRGLNGQEGEVGENGI---DGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGT---- 1498
             P G RG  G  G  G++G+    G  GE+G +GL G KG  GD G  G PG  G     
Sbjct: 504  GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 1499 --PGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR 1556
              PGD G +G  G  GAPG D    GP G +G RG+ G  G+PGP G  G   K    G 
Sbjct: 564  GRPGDAGPQGKVGPSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKA---GE 619

Query: 1557 RGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGN 1616
            +G  G  G  G+PG DG  G+ G  GP GP GE G +G  G  G +G  GPPGP GE G 
Sbjct: 620  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPR------GLQGNDGSPGY-GSVGRKGAKGQEGF 1669
             G  G  G  G PG +G +G  GFPG R      GLQG  G PG  G+ G KGA G  G 
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 1670 PGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEP---------GPPGRKGV 1720
            PG  GP G  G PG  G  G+ G +G     G  G  G+PG+          GPPG  G 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 1721 KGAKG 1725
             G KG
Sbjct: 800  NGEKG 804



 Score =  259 bits (661), Expect = 3e-68
 Identities = 155/345 (44%), Positives = 177/345 (51%), Gaps = 26/345 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG PG  GP G  G+ G  G  G  G  GAPG  G  G  G  G  GP+G  
Sbjct: 387  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G+ GE GI G  GEQG       KGE G  G QG+PG  G  G RGA   RG+P
Sbjct: 447  GPLGPKGQTGEPGIAGFKGEQGP------KGEPGPAGPQGAPGPAGEEGKRGA---RGEP 497

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPG------PPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G  GV     GP G  GERG  G RG+PG      P G PG R  +   G +G  G  G 
Sbjct: 498  G--GV-----GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G PG  G  G  G  G  GP+G+ G  G  G  G  GP GP G  G+ G  G  G +G 
Sbjct: 551  PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610

Query: 1626 KGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGD 1681
             GEPG  GEKG  G PG RGL G DG  G     G  G  G +G++G PG SG +G  G 
Sbjct: 611  NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG PGE G  G +G    AG PG +G  GE G PG +G  GA+GL
Sbjct: 671  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715



 Score =  255 bits (651), Expect = 4e-67
 Identities = 156/388 (40%), Positives = 187/388 (48%), Gaps = 37/388 (9%)

Query: 1392 GGDGTMGDPGPPGKRG---PPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G+PG PG RG    PG  G +G +G  G  GE G PGP G QG +G  G  G  
Sbjct: 546  GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 605

Query: 1449 GNRGLNGQEGEVGENGIDG---LNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G +G NG+ G+ GE G+ G   L G  G +G  G  G  G  G  G  G++G PG  G +
Sbjct: 606  GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665

Query: 1506 GLRGDPGAPGV-----DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG---RR 1557
            GL G PG PG      D  + G  G  G  G +G RG+PG  G+PG++      G     
Sbjct: 666  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 725

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP+G +G  GP G +G  GL+G  G RG AG+ G KG  G  G +GP G  G+ G +
Sbjct: 726  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 785

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----------YGSVGRKGAKGQE 1667
            G  G  G  G  G  GEKG VG PGP G  G  G+PG           G  G  GA GQ 
Sbjct: 786  GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 845

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            G  GE G  G+ GD G PG  G  GA G     G+ G  G+ G  GPPG  G  GA G  
Sbjct: 846  GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG-- 903

Query: 1728 SFSTCELIQYVRDRSPGRHGKPECPVHP 1755
                       R   PG +G P  P  P
Sbjct: 904  -----------RVGPPGSNGNPGPPGPP 920



 Score =  255 bits (651), Expect = 4e-67
 Identities = 148/332 (44%), Positives = 169/332 (50%), Gaps = 20/332 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G +G PG  G  GPPG  G  G  G +G  G+ G PG  GE G +G  G  G KG  
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G +G  G  G  G  GL G++G  GLPG++GE+G     G PG  G PG +GA G  GD 
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG---FPGLPGPSGEPGKQGAPGASGDR 1016

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      GP GL G  G  GR G PG  G PG        G RG TG  G  G PGP
Sbjct: 1017 GPPGP----VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G  G  G  G QG RGEA         G++GP GP GP G  G QG  G +G+KGE G+
Sbjct: 1073 PGSPGPAGPTGKQGDRGEA---------GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1123

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
             GE+G  G  G  GLQG  G PG     G+ G  G  G  G PG  GP G+ G  G PG 
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1183

Query: 1688 TGLKGARGKMISAGLPGEMGSPGEPGPPGRKG 1719
             G  G RG+    G  G  G+PG PGPPG  G
Sbjct: 1184 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score =  254 bits (649), Expect = 7e-67
 Identities = 157/384 (40%), Positives = 184/384 (47%), Gaps = 39/384 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G+ G PG  GP G +G  G +G  G  G  G PG  GE+G  G  G +G  G 
Sbjct: 575  VGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 634

Query: 1451 RGLN---------GQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTP-- 1499
             G           G  GE GE G  G +G QG  G PG  GE G  G QG PG+ G P  
Sbjct: 635  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694

Query: 1500 -GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG 1558
             G RG +G  G+ G+PG    ++GP GL G  G  G +G  GP G PG++      G +G
Sbjct: 695  VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ---GPPGLQG 750

Query: 1559 HTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
              G +G AGI GP G  G +G KGP+G  G+ G +G  G +G  GP G  G  GE G  G
Sbjct: 751  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              GS G +G PG+ GE G  G  G  G  G DG PG  G  G  G KG  G PG  GP G
Sbjct: 811  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870

Query: 1678 EIGDPGGPGETGLKGARGKMISAGL------------PGEMGSPGEPGPPGRKGVKGAKG 1725
              G  G  G TG KGARG     G             PG  G+PG PGPPG  G  G KG
Sbjct: 871  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930

Query: 1726 LASFSTCELIQYVRDRSPGRHGKP 1749
                S            PGR G+P
Sbjct: 931  ARGDS----------GPPGRAGEP 944



 Score =  251 bits (640), Expect = 7e-66
 Identities = 162/394 (41%), Positives = 192/394 (48%), Gaps = 63/394 (15%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG---PVGEQGTKGCYGTKGPK 1448
            G  G +G  GPPG+RG PG   + G+ G++G+AG +GAPG   P G  G KG  G  G  
Sbjct: 495  GEPGGVGPIGPPGERGAPG---NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPG---RKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  GL G  G  G  G  G  G+ G +G PG   R G  G +G++G PG  G PG +GA 
Sbjct: 552  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 1506 GL------RGDPGAPGV-----------DSSIEGPTGLKGERGRQGR------RGWPGPP 1542
            G       +G PGAPG+            +   GP G  GERG QG       +G PGPP
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 1543 GTPGSRRKTAAHGRRGH------TGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEK 1596
            G PG   K    G  G        GP+G  G PG  G  G+ GL+GP+G  G  G  G K
Sbjct: 672  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731

Query: 1597 GGVGSKGP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGP---RGLQGND 1650
            G  G  GP   QGPPG  G  G +G  G  G KG+ GD+GEKG  G PG    RGL G  
Sbjct: 732  GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 791

Query: 1651 GSPG----------------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            G PG                 GS G +GA G+ G  G  GP G  G PG  G+ G KG +
Sbjct: 792  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851

Query: 1695 ---GKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
               G+   AG PG  G  G PGP G  GV G KG
Sbjct: 852  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 885



 Score =  249 bits (635), Expect = 3e-65
 Identities = 159/410 (38%), Positives = 194/410 (47%), Gaps = 75/410 (18%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG----- 1446
            G  G  G  GPPG +GPPG +G  G  G  GIAG +G  G VGE+G +G  G  G     
Sbjct: 729  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788

Query: 1447 ----PKGNRGLNGQEGEVG------ENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKR 1496
                P G  G NG++GEVG        G  G  GE+G+ G PG  G  G  G+ G PG +
Sbjct: 789  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 1497 GTPGDRGAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQGRRGWPG------------PP 1542
            G  G+ G KG  G PG  G   +   +GPTG+ G +G +G +G PG            PP
Sbjct: 849  GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 1543 GTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
            G+ G+       G  G  GP+G  G  GP G  G  GL+GP GP GE G  G+ G  G++
Sbjct: 909  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968

Query: 1603 GPQGP------------------------PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAV 1638
            GP GP                        PGP GE G QG  G+ G++G PG +G  G  
Sbjct: 969  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028

Query: 1639 G---FPGPRGLQGNDGSPGY-------------GSVGRKGAKGQEGFPGESGPKGEIGDP 1682
            G    PG  G  G DG PG              G+VG  GA G  G PG +GP G+ GD 
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088

Query: 1683 G-----GP-GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            G     GP G +G  GARG     G  G+ G  GEPG  G KG +G  GL
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1138



 Score =  248 bits (633), Expect = 5e-65
 Identities = 157/374 (41%), Positives = 176/374 (47%), Gaps = 39/374 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  G  G+ GPPG  GS G  G  G  GE G PGP G  G  G  G  G KG 
Sbjct: 791  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR---GAKGL 1507
            +G  GQ+G+ G  G  G +G  G  G  G  G KG  G+QG PG  G PG     G  G 
Sbjct: 851  QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910

Query: 1508 RGDPGAPGV--DSSIEGPTGLKGERGRQGRRGWP------GPPGTPGSRRKTAAHGRRGH 1559
             G+PG PG    S  +GP G +G+ G  GR G P      GPPG  G        G  G 
Sbjct: 911  NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 970

Query: 1560 TGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGE 1613
             GPQG A      G+PG  G  G  GL GP G  G+ G  G  G  G  GP GPPG  G 
Sbjct: 971  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030

Query: 1614 AGNQGRLGSQGNKGEP---------GDLGEKGAVGFP------------GPRGLQGNDGS 1652
            AG  GR GS G  G P         GD GE GAVG P            GP G QG+ G 
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 1653 PG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
             G  G +G  G  G  G  G  GP+G+ G+ G PGE GLKG RG     GLPG  G  G+
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 1712 PGPPGRKGVKGAKG 1725
             G  G  G  G +G
Sbjct: 1151 QGASGPAGPSGPRG 1164



 Score =  245 bits (625), Expect = 4e-64
 Identities = 147/344 (42%), Positives = 167/344 (48%), Gaps = 29/344 (8%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG  G RG  G  G  G  G  G  GE G PGP G  G +G  G +G  G 
Sbjct: 770  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
             G  G  G  G +G  G  GEQG+ G  G  G  G +G  G+PG +G  G  G KG RG 
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             G PG      G  G  G  G  G  G PGPPG PG   K    G RG +GP G AG P 
Sbjct: 890  QGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP- 944

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPG 1630
                    GL+GP GP GE   KGE G  G  G +GPPGP G AG +G +G       PG
Sbjct: 945  --------GLQGPAGPPGE---KGEPGDDGPSGAEGPPGPQGLAGQRGIVGL------PG 987

Query: 1631 DLGEKGAVGFPGPRGLQGNDGSPGY-------GSVGRKGAKGQEGFPGESGPKGEIGDPG 1683
              GE+G  G PGP G  G  G+PG        G VG  G  G  G PG  G  G  G PG
Sbjct: 988  QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 1047

Query: 1684 GPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
              G  G+KG RG+  + G PG  G PG PGP G  G +G +G A
Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1091



 Score =  243 bits (619), Expect = 2e-63
 Identities = 156/395 (39%), Positives = 176/395 (44%), Gaps = 61/395 (15%)

Query: 1392 GGDGTMGDPG-------PPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGT 1444
            G  G  G+PG       P G  GP G  G +G  G+ G  GE+GAPGP G  G  G  G 
Sbjct: 101  GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 160

Query: 1445 KGPKGNRGLNGQEGEVGE------NGID------------GLNGEQGDNGLPGRKGEKGD 1486
             GP G  G  G  G  G        G D            G  G  G  G PG  G  G 
Sbjct: 161  PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 220

Query: 1487 EGSQGSPGKRGTPGDRGAKGLRGDPGAPGV--DSSIEGPTGLKGER---GRQGRRGWPGP 1541
            +G QG+PG+ G PG  G  G RG PG PG   D    G  G  GER   G QG RG+PG 
Sbjct: 221  QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 280

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPR---------GEAGV 1592
            PG PG +      G  G  G  G  G+ G  G  G  G  GP GPR         G AG 
Sbjct: 281  PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA 340

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGS 1652
             G +G  G  GP GPPGP G AG  G  G+ G KGE G  G +G  G  GPRG  G  GS
Sbjct: 341  AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400

Query: 1653 PG----------------YGSVGRKGAKGQEGFPGESGP------KGEIGDPGGPGETGL 1690
            PG                 GS G  G  G  GFPG  GP       G +G  G  GE G+
Sbjct: 401  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G +G+    G PG  G  G PGP G +G +GA+G
Sbjct: 461  AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG 495



 Score =  206 bits (523), Expect = 3e-52
 Identities = 124/309 (40%), Positives = 144/309 (46%), Gaps = 44/309 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G +G  G PGPPG  G  G KG+ G  G  G AGE G  GP G  G KG  G  GP G  
Sbjct: 909  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK---RGTPGDRGAKGLR 1508
            G  G +G  G+ GI GL G++G+ G PG  G  G+ G QG+PG    RG PG  G  GL 
Sbjct: 969  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028

Query: 1509 GDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT 1560
            G  G PG + S         +G  G+KG+RG  G  G PG PG PGS       G++G  
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088

Query: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG----------------- 1603
            G  G  G  GP G  G+ G++GPQGPRG+ G  GE G  G KG                 
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148

Query: 1604 ----------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQ 1647
                            P GP GP G+ G  G  G  G  G  G  GE G  G PG  G  
Sbjct: 1149 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208

Query: 1648 GNDGSPGYG 1656
            G  G PG G
Sbjct: 1209 GPPGPPGPG 1217



 Score =  168 bits (426), Expect = 5e-41
 Identities = 116/298 (38%), Positives = 139/298 (46%), Gaps = 50/298 (16%)

Query: 1475 NGLPGRKGEKGDEGS-------QGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLK 1527
            +G PG KG+KG+ G        +G PG +G  G++G +G RGD                K
Sbjct: 97   SGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD----------------K 140

Query: 1528 GERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG-- 1585
            GE+G  G RG  G PGTPG+             GP G  G PGP GL G+   +   G  
Sbjct: 141  GEKGAPGPRGRDGEPGTPGN------------PGPPGPPGPPGPPGLGGNFAAQMAGGFD 188

Query: 1586 -PRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
               G A +   +G +G  GP+GPPGP G  G QG  G+ G  GEPG  G  G  G PGP 
Sbjct: 189  EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPP 248

Query: 1645 GLQGNDGSPG-------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKM 1697
            G  G+DG  G        G  G +GA+G  G PG  G KG  G PG  G  G  GA G  
Sbjct: 249  GKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 308

Query: 1698 ISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
              +G PGE GSPG  GP G  G +G  G A  +         D  PG  G P  PV P
Sbjct: 309  GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR----GNDGQPGPAGPPG-PVGP 361



 Score =  168 bits (426), Expect = 5e-41
 Identities = 111/309 (35%), Positives = 133/309 (43%), Gaps = 71/309 (22%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKG------SEGYLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G  GD GPPG+ G PG +G       +G  G++G +G  G PGP G  G +G  G  
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGR------KGEKGDEGSQGSPGKRGTP 1499
            G +G RG  G  G  GE G  G  G  GD G PG        G  G+ G +GSPG  G P
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 1500 GDRGAKGLRGD---------PGAPGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  GA G++GD         PGAPG   S    GPTG +G+RG  G +G  GP G  G+R
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 1549 R------------------KTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRG-- 1588
                               +    G RG TG QG  G PGP G +G+ G  GP GPRG  
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166

Query: 1589 ----------------------------EAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL 1620
                                        E G  G  G  G  GP GPPGPG +      L
Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1226

Query: 1621 GSQGNKGEP 1629
            G +    +P
Sbjct: 1227 GPREKGPDP 1235



 Score =  163 bits (413), Expect = 2e-39
 Identities = 106/276 (38%), Positives = 122/276 (44%), Gaps = 52/276 (18%)

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            G  G KG +G+PG       I+   G KG  G QG  G  GP G  G + +  A G RG 
Sbjct: 98   GQPGPKGQKGEPG------DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGR 151

Query: 1560 TGPQGTAGIPGPDG---------------------------------LEGSLGLKGPQGP 1586
             G  GT G PGP G                                 ++G +G  GP+GP
Sbjct: 152  DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211

Query: 1587 RGEAGV------------KGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE 1634
             G AG              GE G  G  GP+GPPGP G+ G+ G  G  G  GE G  G 
Sbjct: 212  PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271

Query: 1635 KGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGA 1693
            +GA GFPG  GL G  G  GY G  G KG  G  G  GESG  GE G PG  G  GL G 
Sbjct: 272  QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331

Query: 1694 RGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            RG+   AG  G  G+ G+PGP G  G  G  G   F
Sbjct: 332  RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367



 Score =  127 bits (319), Expect = 1e-28
 Identities = 75/181 (41%), Positives = 85/181 (46%), Gaps = 28/181 (15%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG  GP          G++G  GE GA GP+G  G  G  G +GP+G 
Sbjct: 1064 VGAPGAPGPPGSPGPAGP---------TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            RG  G+ GE GE G+ G  G  G  GLPG  G  GD+G+ G  G  G  G  G  G  G 
Sbjct: 1115 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             GA G    I GP G  G RGR G  G  GPPG P               GP G  G PG
Sbjct: 1175 DGANG----IPGPIGPPGPRGRSGETGPAGPPGNP---------------GPPGPPGPPG 1215

Query: 1571 P 1571
            P
Sbjct: 1216 P 1216



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 56/154 (36%), Positives = 62/154 (40%), Gaps = 35/154 (22%)

Query: 1607 PPGPGGEAGNQGRLGSQGNKGEPGDL----GEKGAVGFPGPRGLQGNDGSPG----YGSV 1658
            P  P   A   G+ G +G KGEPGD+    G KG  G  GP G QG  G  G     G+ 
Sbjct: 87   PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146

Query: 1659 GRKGAKGQEGFPGESGPKGEIGDPGGP---------------------------GETGLK 1691
            G +G  G+ G PG  GP G  G PG P                           G  G  
Sbjct: 147  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 1692 GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G RG    AG PG  G  G PG PG  GV G  G
Sbjct: 207  GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG 240


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  282 bits (721), Expect = 3e-75
 Identities = 163/374 (43%), Positives = 192/374 (51%), Gaps = 41/374 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQG---TKGCYGTKGPK 1448
            G  G  G  GP G  GPPG  G +G  G+ G AGERG PGP G +G   T G  G KG +
Sbjct: 162  GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 221

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG---------------DEGSQGSP 1493
            G  GL+G +GE G  G+ G +G  G+NG PG  G +G                 G+ G P
Sbjct: 222  GYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQP 281

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAA 1553
            G  G PG  G  G  G PGAPG      GPTG +G  G QG RG PG PG+PG    +  
Sbjct: 282  GPAGPPGPVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340

Query: 1554 HGRRGHTGPQGTAG---------IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
             G  G  G +G+AG          PGP G  G  G  GP GP+G+ G  G  G  G +GP
Sbjct: 341  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 400

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGA 1663
            +G PGP G  G  G  G +G +G  G+ G  G +G PG RG  GN G PG  G  G KGA
Sbjct: 401  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460

Query: 1664 KGQEGFPGESGPKGEIGDPGGPGETGLKGAR------------GKMISAGLPGEMGSPGE 1711
             G+ G  G +GPKG  GDPG PGE GL GAR            GK+  +G PGE G PG 
Sbjct: 461  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 1712 PGPPGRKGVKGAKG 1725
            PGP G +G  G  G
Sbjct: 521  PGPQGARGQPGVMG 534



 Score =  269 bits (687), Expect = 3e-71
 Identities = 159/377 (42%), Positives = 186/377 (49%), Gaps = 27/377 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GD G PG +GP G  G +G  G  G  G RGA GP G  G  G  G  GP G+ 
Sbjct: 783  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSN 842

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G +G DG  G +GD+G PGR GE G +G  G PG++G PGD G  G  G P
Sbjct: 843  GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 902

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G  G+     G  GL G+RG +G  G PGP G PG +    A G RG  GP G  G+ GP
Sbjct: 903  GPQGLAGQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961

Query: 1572 ---DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
                G EGS G  GP G  G AGVKG++G  G+ G  G PGP G  G  G  G QG++GE
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGF------PGESGPKGE 1678
             G  G  G  G  G RG+QG  G  G     G  G +G KG  GF      PG  GP G+
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 1679 IGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYV 1738
             G  G  G +G +G  G +  +G  G  G PG  GPPG +G  G  G A           
Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG---------- 1131

Query: 1739 RDRSPGRHGKPECPVHP 1755
                PG  G P  P  P
Sbjct: 1132 ---PPGNPGPPGPPGPP 1145



 Score =  266 bits (679), Expect = 2e-70
 Identities = 151/342 (44%), Positives = 177/342 (51%), Gaps = 13/342 (3%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT G  GP G  GP G  G++G  G +G+ GERGA G  G +G +G  G KGP+G  
Sbjct: 651  GLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 710

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G +G  G  G  G  G  G  G+ G  G  G  G  G++G+PG+RG  G  G  G  G P
Sbjct: 711  GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770

Query: 1512 GAPGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
            GA G   +   +G  G KG+ G  G +G  G PG  G    T   G RG  GP G  G P
Sbjct: 771  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830

Query: 1570 GPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEP 1629
            G  G  G  G  G  GP G  G  G+ G  G++G  GPPG  GE G QG  G  G KGEP
Sbjct: 831  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 1630 GDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETG 1689
            GD G  GA G PGP+GL G       G VG  G +G+ GFPG  GP GE G  G PG +G
Sbjct: 891  GDDGPSGAEGPPGPQGLAGQ-----RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 945

Query: 1690 LKGARGKMISAGL------PGEMGSPGEPGPPGRKGVKGAKG 1725
             +G  G +   GL      PG  GSPG  GPPGR G  G KG
Sbjct: 946  DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987



 Score =  262 bits (669), Expect = 3e-69
 Identities = 159/379 (41%), Positives = 188/379 (49%), Gaps = 50/379 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG  G++G PG  G  G  G++G  G  G PGP G  G +G  G  GP G +
Sbjct: 537  GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 596

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G  G  GE G  G  G  G+ G PG  G +G+   +G PG+RG+PG +G +G RG P
Sbjct: 597  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE---RGFPGERGSPGAQGLQGPRGLP 653

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG D    GP G  G  G  G +G PG  G PG R      G +G  G  G  G  G 
Sbjct: 654  GTPGTD----GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 709

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP---------------QGPPGPGGEAGN 1616
             G +G  GL GP GP G AG  GEKG VG  GP                GPPGP G AG 
Sbjct: 710  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 769

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGES-- 1673
             G  G  G KGE G+ G+KG  G PGP+G  G  G  G  G  G KGA+G +G PG +  
Sbjct: 770  PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGF 829

Query: 1674 -------GPKGEIGDPGGP------GETGLKGARGK------------MISAGLPGEMGS 1708
                   GP G  G+PG P      G+ G KGARG                AG PGE G 
Sbjct: 830  PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 889

Query: 1709 PGEPGPPGRKGVKGAKGLA 1727
            PG+ GP G +G  G +GLA
Sbjct: 890  PGDDGPSGAEGPPGPQGLA 908



 Score =  261 bits (667), Expect = 6e-69
 Identities = 167/405 (41%), Positives = 201/405 (49%), Gaps = 44/405 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAG----ERGAP-----GPVGEQGTKGCY 1442
            G  GT G+PGPPG  GPPG  G  G    +   G      GA      GP+G  G +G  
Sbjct: 84   GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  G  G +G  G  GE GE G+ G  G +G  G PG+ G+ G+ G  G  G+RG PG +
Sbjct: 144  GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 1503 GAKGLRGDPGAPGVD-----------SSIEGPTGLKGERGRQGRRGWP---GPPGTPGSR 1548
            GA+G  G PG PGV                G  G+KGE G  G  G P   GP G PG R
Sbjct: 204  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 1549 RKT---AAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQ 1605
             +T    A G RG+ G  G AG PGP G  G  G  G  G +GEAG  G +G  G++GP+
Sbjct: 264  GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323

Query: 1606 ------GPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSV 1658
                  G PGP G +GN G  G  G KG  G  G  GA GFPGPRG  G  G+ G  G  
Sbjct: 324  GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383

Query: 1659 GRKGAKGQEGFPGESGPKGEIGD------PGGPGETGLKGARGK---MISAGLPGEMGSP 1709
            G+ G  G  GF GE GPKGE G       PG  GE G +GARG+   +   G PGE G+P
Sbjct: 384  GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP 443

Query: 1710 GEPGPPGRKGVKGAKGLASFSTCELIQYVR--DRSPGRHGKPECP 1752
            G  G PG+ G+ G KG         +   +  +  PGR G+P  P
Sbjct: 444  GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488



 Score =  261 bits (667), Expect = 6e-69
 Identities = 158/365 (43%), Positives = 185/365 (50%), Gaps = 35/365 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG----- 1446
            G  G +G  G  G+ G  GFKG +G  GE G AG +GAPGP GE+G +G  G  G     
Sbjct: 375  GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 1447 -PKGNRGLNGQEGEVGENGI---DGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGT---- 1498
             P G RG  G  G  G++G+    G  GE+G +GL G KG  GD G  G PG  G     
Sbjct: 435  GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 1499 --PGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR 1556
              PGD G +G  G  GAPG D    GP G +G RG+ G  G+PGP G  G   K    G 
Sbjct: 495  GRPGDAGPQGKVGPSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKA---GE 550

Query: 1557 RGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGN 1616
            +G  G  G  G+PG DG  G+ G  GP GP GE G +G  G  G +G  GPPGP GE G 
Sbjct: 551  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPR------GLQGNDGSPGY-GSVGRKGAKGQEGF 1669
             G  G  G  G PG +G +G  GFPG R      GLQG  G PG  G+ G KGA G  G 
Sbjct: 611  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670

Query: 1670 PGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEP---------GPPGRKGV 1720
            PG  GP G  G PG  G  G+ G +G     G  G  G+PG+          GPPG  G 
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 1721 KGAKG 1725
             G KG
Sbjct: 731  NGEKG 735



 Score =  259 bits (661), Expect = 3e-68
 Identities = 155/345 (44%), Positives = 177/345 (51%), Gaps = 26/345 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG PG  GP G  G+ G  G  G  G  GAPG  G  G  G  G  GP+G  
Sbjct: 318  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G+ GE GI G  GEQG       KGE G  G QG+PG  G  G RGA   RG+P
Sbjct: 378  GPLGPKGQTGEPGIAGFKGEQGP------KGEPGPAGPQGAPGPAGEEGKRGA---RGEP 428

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPG------PPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G  GV     GP G  GERG  G RG+PG      P G PG R  +   G +G  G  G 
Sbjct: 429  G--GV-----GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G PG  G  G  G  G  GP+G+ G  G  G  G  GP GP G  G+ G  G  G +G 
Sbjct: 482  PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541

Query: 1626 KGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGD 1681
             GEPG  GEKG  G PG RGL G DG  G     G  G  G +G++G PG SG +G  G 
Sbjct: 542  NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG PGE G  G +G    AG PG +G  GE G PG +G  GA+GL
Sbjct: 602  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646



 Score =  255 bits (651), Expect = 4e-67
 Identities = 156/388 (40%), Positives = 187/388 (48%), Gaps = 37/388 (9%)

Query: 1392 GGDGTMGDPGPPGKRG---PPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G+PG PG RG    PG  G +G +G  G  GE G PGP G QG +G  G  G  
Sbjct: 477  GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536

Query: 1449 GNRGLNGQEGEVGENGIDG---LNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G +G NG+ G+ GE G+ G   L G  G +G  G  G  G  G  G  G++G PG  G +
Sbjct: 537  GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 596

Query: 1506 GLRGDPGAPGV-----DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG---RR 1557
            GL G PG PG      D  + G  G  G  G +G RG+PG  G+PG++      G     
Sbjct: 597  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 656

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP+G +G  GP G +G  GL+G  G RG AG+ G KG  G  G +GP G  G+ G +
Sbjct: 657  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 716

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----------YGSVGRKGAKGQE 1667
            G  G  G  G  G  GEKG VG PGP G  G  G+PG           G  G  GA GQ 
Sbjct: 717  GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 776

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            G  GE G  G+ GD G PG  G  GA G     G+ G  G+ G  GPPG  G  GA G  
Sbjct: 777  GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG-- 834

Query: 1728 SFSTCELIQYVRDRSPGRHGKPECPVHP 1755
                       R   PG +G P  P  P
Sbjct: 835  -----------RVGPPGSNGNPGPPGPP 851



 Score =  255 bits (651), Expect = 4e-67
 Identities = 148/332 (44%), Positives = 169/332 (50%), Gaps = 20/332 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G +G PG  G  GPPG  G  G  G +G  G+ G PG  GE G +G  G  G KG  
Sbjct: 831  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G +G  G  G  G  GL G++G  GLPG++GE+G     G PG  G PG +GA G  GD 
Sbjct: 891  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG---FPGLPGPSGEPGKQGAPGASGDR 947

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      GP GL G  G  GR G PG  G PG        G RG TG  G  G PGP
Sbjct: 948  GPPGP----VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1003

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G  G  G  G QG RGEA         G++GP GP GP G  G QG  G +G+KGE G+
Sbjct: 1004 PGSPGPAGPTGKQGDRGEA---------GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1054

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
             GE+G  G  G  GLQG  G PG     G+ G  G  G  G PG  GP G+ G  G PG 
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1114

Query: 1688 TGLKGARGKMISAGLPGEMGSPGEPGPPGRKG 1719
             G  G RG+    G  G  G+PG PGPPG  G
Sbjct: 1115 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146



 Score =  254 bits (649), Expect = 7e-67
 Identities = 157/384 (40%), Positives = 184/384 (47%), Gaps = 39/384 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G+ G PG  GP G +G  G +G  G  G  G PG  GE+G  G  G +G  G 
Sbjct: 506  VGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 565

Query: 1451 RGLN---------GQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTP-- 1499
             G           G  GE GE G  G +G QG  G PG  GE G  G QG PG+ G P  
Sbjct: 566  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625

Query: 1500 -GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG 1558
             G RG +G  G+ G+PG    ++GP GL G  G  G +G  GP G PG++      G +G
Sbjct: 626  VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ---GPPGLQG 681

Query: 1559 HTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
              G +G AGI GP G  G +G KGP+G  G+ G +G  G +G  GP G  G  GE G  G
Sbjct: 682  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              GS G +G PG+ GE G  G  G  G  G DG PG  G  G  G KG  G PG  GP G
Sbjct: 742  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801

Query: 1678 EIGDPGGPGETGLKGARGKMISAGL------------PGEMGSPGEPGPPGRKGVKGAKG 1725
              G  G  G TG KGARG     G             PG  G+PG PGPPG  G  G KG
Sbjct: 802  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861

Query: 1726 LASFSTCELIQYVRDRSPGRHGKP 1749
                S            PGR G+P
Sbjct: 862  ARGDS----------GPPGRAGEP 875



 Score =  251 bits (640), Expect = 7e-66
 Identities = 162/394 (41%), Positives = 192/394 (48%), Gaps = 63/394 (15%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG---PVGEQGTKGCYGTKGPK 1448
            G  G +G  GPPG+RG PG   + G+ G++G+AG +GAPG   P G  G KG  G  G  
Sbjct: 426  GEPGGVGPIGPPGERGAPG---NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPG---RKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  GL G  G  G  G  G  G+ G +G PG   R G  G +G++G PG  G PG +GA 
Sbjct: 483  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 1506 GL------RGDPGAPGV-----------DSSIEGPTGLKGERGRQGR------RGWPGPP 1542
            G       +G PGAPG+            +   GP G  GERG QG       +G PGPP
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 1543 GTPGSRRKTAAHGRRGH------TGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEK 1596
            G PG   K    G  G        GP+G  G PG  G  G+ GL+GP+G  G  G  G K
Sbjct: 603  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662

Query: 1597 GGVGSKGP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGP---RGLQGND 1650
            G  G  GP   QGPPG  G  G +G  G  G KG+ GD+GEKG  G PG    RGL G  
Sbjct: 663  GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 722

Query: 1651 GSPG----------------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            G PG                 GS G +GA G+ G  G  GP G  G PG  G+ G KG +
Sbjct: 723  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782

Query: 1695 ---GKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
               G+   AG PG  G  G PGP G  GV G KG
Sbjct: 783  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 816



 Score =  249 bits (635), Expect = 3e-65
 Identities = 159/410 (38%), Positives = 194/410 (47%), Gaps = 75/410 (18%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG----- 1446
            G  G  G  GPPG +GPPG +G  G  G  GIAG +G  G VGE+G +G  G  G     
Sbjct: 660  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719

Query: 1447 ----PKGNRGLNGQEGEVG------ENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKR 1496
                P G  G NG++GEVG        G  G  GE+G+ G PG  G  G  G+ G PG +
Sbjct: 720  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 1497 GTPGDRGAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQGRRGWPG------------PP 1542
            G  G+ G KG  G PG  G   +   +GPTG+ G +G +G +G PG            PP
Sbjct: 780  GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 1543 GTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
            G+ G+       G  G  GP+G  G  GP G  G  GL+GP GP GE G  G+ G  G++
Sbjct: 840  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899

Query: 1603 GPQGP------------------------PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAV 1638
            GP GP                        PGP GE G QG  G+ G++G PG +G  G  
Sbjct: 900  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959

Query: 1639 G---FPGPRGLQGNDGSPGY-------------GSVGRKGAKGQEGFPGESGPKGEIGDP 1682
            G    PG  G  G DG PG              G+VG  GA G  G PG +GP G+ GD 
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019

Query: 1683 G-----GP-GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            G     GP G +G  GARG     G  G+ G  GEPG  G KG +G  GL
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1069



 Score =  248 bits (633), Expect = 5e-65
 Identities = 157/374 (41%), Positives = 176/374 (47%), Gaps = 39/374 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  G  G+ GPPG  GS G  G  G  GE G PGP G  G  G  G  G KG 
Sbjct: 722  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR---GAKGL 1507
            +G  GQ+G+ G  G  G +G  G  G  G  G KG  G+QG PG  G PG     G  G 
Sbjct: 782  QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841

Query: 1508 RGDPGAPGV--DSSIEGPTGLKGERGRQGRRGWP------GPPGTPGSRRKTAAHGRRGH 1559
             G+PG PG    S  +GP G +G+ G  GR G P      GPPG  G        G  G 
Sbjct: 842  NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 901

Query: 1560 TGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGE 1613
             GPQG A      G+PG  G  G  GL GP G  G+ G  G  G  G  GP GPPG  G 
Sbjct: 902  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961

Query: 1614 AGNQGRLGSQGNKGEP---------GDLGEKGAVGFP------------GPRGLQGNDGS 1652
            AG  GR GS G  G P         GD GE GAVG P            GP G QG+ G 
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 1653 PG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
             G  G +G  G  G  G  G  GP+G+ G+ G PGE GLKG RG     GLPG  G  G+
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 1712 PGPPGRKGVKGAKG 1725
             G  G  G  G +G
Sbjct: 1082 QGASGPAGPSGPRG 1095



 Score =  245 bits (625), Expect = 4e-64
 Identities = 147/344 (42%), Positives = 167/344 (48%), Gaps = 29/344 (8%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG  G RG  G  G  G  G  G  GE G PGP G  G +G  G +G  G 
Sbjct: 701  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
             G  G  G  G +G  G  GEQG+ G  G  G  G +G  G+PG +G  G  G KG RG 
Sbjct: 761  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             G PG      G  G  G  G  G  G PGPPG PG   K    G RG +GP G AG P 
Sbjct: 821  QGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP- 875

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPG 1630
                    GL+GP GP GE   KGE G  G  G +GPPGP G AG +G +G       PG
Sbjct: 876  --------GLQGPAGPPGE---KGEPGDDGPSGAEGPPGPQGLAGQRGIVGL------PG 918

Query: 1631 DLGEKGAVGFPGPRGLQGNDGSPGY-------GSVGRKGAKGQEGFPGESGPKGEIGDPG 1683
              GE+G  G PGP G  G  G+PG        G VG  G  G  G PG  G  G  G PG
Sbjct: 919  QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 978

Query: 1684 GPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
              G  G+KG RG+  + G PG  G PG PGP G  G +G +G A
Sbjct: 979  RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1022



 Score =  243 bits (619), Expect = 2e-63
 Identities = 156/395 (39%), Positives = 176/395 (44%), Gaps = 61/395 (15%)

Query: 1392 GGDGTMGDPG-------PPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGT 1444
            G  G  G+PG       P G  GP G  G +G  G+ G  GE+GAPGP G  G  G  G 
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 1445 KGPKGNRGLNGQEGEVGE------NGID------------GLNGEQGDNGLPGRKGEKGD 1486
             GP G  G  G  G  G        G D            G  G  G  G PG  G  G 
Sbjct: 92   PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 151

Query: 1487 EGSQGSPGKRGTPGDRGAKGLRGDPGAPGV--DSSIEGPTGLKGER---GRQGRRGWPGP 1541
            +G QG+PG+ G PG  G  G RG PG PG   D    G  G  GER   G QG RG+PG 
Sbjct: 152  QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 211

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPR---------GEAGV 1592
            PG PG +      G  G  G  G  G+ G  G  G  G  GP GPR         G AG 
Sbjct: 212  PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA 271

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGS 1652
             G +G  G  GP GPPGP G AG  G  G+ G KGE G  G +G  G  GPRG  G  GS
Sbjct: 272  AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 331

Query: 1653 PG----------------YGSVGRKGAKGQEGFPGESGP------KGEIGDPGGPGETGL 1690
            PG                 GS G  G  G  GFPG  GP       G +G  G  GE G+
Sbjct: 332  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 391

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G +G+    G PG  G  G PGP G +G +GA+G
Sbjct: 392  AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG 426



 Score =  206 bits (523), Expect = 3e-52
 Identities = 124/309 (40%), Positives = 144/309 (46%), Gaps = 44/309 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G +G  G PGPPG  G  G KG+ G  G  G AGE G  GP G  G KG  G  GP G  
Sbjct: 840  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK---RGTPGDRGAKGLR 1508
            G  G +G  G+ GI GL G++G+ G PG  G  G+ G QG+PG    RG PG  G  GL 
Sbjct: 900  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959

Query: 1509 GDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT 1560
            G  G PG + S         +G  G+KG+RG  G  G PG PG PGS       G++G  
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019

Query: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG----------------- 1603
            G  G  G  GP G  G+ G++GPQGPRG+ G  GE G  G KG                 
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079

Query: 1604 ----------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQ 1647
                            P GP GP G+ G  G  G  G  G  G  GE G  G PG  G  
Sbjct: 1080 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139

Query: 1648 GNDGSPGYG 1656
            G  G PG G
Sbjct: 1140 GPPGPPGPG 1148



 Score =  168 bits (426), Expect = 5e-41
 Identities = 111/309 (35%), Positives = 133/309 (43%), Gaps = 71/309 (22%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKG------SEGYLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G  GD GPPG+ G PG +G       +G  G++G +G  G PGP G  G +G  G  
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGR------KGEKGDEGSQGSPGKRGTP 1499
            G +G RG  G  G  GE G  G  G  GD G PG        G  G+ G +GSPG  G P
Sbjct: 918  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 1500 GDRGAKGLRGD---------PGAPGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  GA G++GD         PGAPG   S    GPTG +G+RG  G +G  GP G  G+R
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 1549 R------------------KTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRG-- 1588
                               +    G RG TG QG  G PGP G +G+ G  GP GPRG  
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097

Query: 1589 ----------------------------EAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL 1620
                                        E G  G  G  G  GP GPPGPG +      L
Sbjct: 1098 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1157

Query: 1621 GSQGNKGEP 1629
            G +    +P
Sbjct: 1158 GPREKGPDP 1166



 Score =  166 bits (421), Expect = 2e-40
 Identities = 115/295 (38%), Positives = 137/295 (46%), Gaps = 50/295 (16%)

Query: 1478 PGRKGEKGDEGS-------QGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGER 1530
            PG KG+KG+ G        +G PG +G  G++G +G RGD                KGE+
Sbjct: 31   PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD----------------KGEK 74

Query: 1531 GRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG---PR 1587
            G  G RG  G PGTPG+             GP G  G PGP GL G+   +   G     
Sbjct: 75   GAPGPRGRDGEPGTPGN------------PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 122

Query: 1588 GEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQ 1647
            G A +   +G +G  GP+GPPGP G  G QG  G+ G  GEPG  G  G  G PGP G  
Sbjct: 123  GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 182

Query: 1648 GNDGSPG-------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISA 1700
            G+DG  G        G  G +GA+G  G PG  G KG  G PG  G  G  GA G    +
Sbjct: 183  GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242

Query: 1701 GLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
            G PGE GSPG  GP G  G +G  G A  +         D  PG  G P  PV P
Sbjct: 243  GSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR----GNDGQPGPAGPPG-PVGP 292



 Score =  127 bits (319), Expect = 1e-28
 Identities = 75/181 (41%), Positives = 85/181 (46%), Gaps = 28/181 (15%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG  GP          G++G  GE GA GP+G  G  G  G +GP+G 
Sbjct: 995  VGAPGAPGPPGSPGPAGP---------TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            RG  G+ GE GE G+ G  G  G  GLPG  G  GD+G+ G  G  G  G  G  G  G 
Sbjct: 1046 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             GA G    I GP G  G RGR G  G  GPPG P               GP G  G PG
Sbjct: 1106 DGANG----IPGPIGPPGPRGRSGETGPAGPPGNP---------------GPPGPPGPPG 1146

Query: 1571 P 1571
            P
Sbjct: 1147 P 1147


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  280 bits (716), Expect = 1e-74
 Identities = 174/406 (42%), Positives = 202/406 (49%), Gaps = 52/406 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGPPG  GP G  G +G  G  G  GERG PGP G +G  G  G  G KG+R
Sbjct: 207  GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHR 266

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G +G+ GE GE G  GL GE   NGLPG  G  G  G +G+PG+RG PG  GA G RG+ 
Sbjct: 267  GFDGRNGEKGETGAPGLKGE---NGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGND 323

Query: 1512 GAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI- 1568
            GA G D      GP G  G  G  G +G  GP G+PGS     A G+RG  GPQG AG  
Sbjct: 324  GARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS---NGAPGQRGEPGPQGHAGAQ 380

Query: 1569 --PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNK 1626
              PGP G+ GS G KG  GP G  G  G  G  G  GP G  G  G  G  G  G  G K
Sbjct: 381  GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440

Query: 1627 GEPGDLGEKGAVGF---PGPRGLQGNDGSPG-------------------------YGSV 1658
            GEPG  GE+G  G    PG +G  G DGSPG                          G  
Sbjct: 441  GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP 500

Query: 1659 GRKGAKGQEGFPGESGPKGEIGD------PGGPGETGLKGARGKMISAGLPGEMGSPGE- 1711
            G KG  G+ G PG +GP+G  G+      PGGPG  G+ G+ G   S G PG  GS GE 
Sbjct: 501  GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560

Query: 1712 --PGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
              PGPPG  G +G  G+  F   +      D +PG++G+   P  P
Sbjct: 561  GRPGPPGPSGPRGQPGVMGFPGPK----GNDGAPGKNGERGGPGGP 602



 Score =  270 bits (689), Expect = 2e-71
 Identities = 161/357 (45%), Positives = 179/357 (50%), Gaps = 29/357 (8%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGS---EGYLGEEGIAGERGAPGPVG------------EQ 1436
            G  G  G PGPPG  G PG KG     G  G  G+ G RG PGP G            E 
Sbjct: 375  GHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEP 434

Query: 1437 GTKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSP 1493
            G  G  G  GP+G RG   + G  G  GE+G DG  GE G NGLPG  GE+G  G +G  
Sbjct: 435  GKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA 494

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAA 1553
            G  G PG++G  G RG PG  G   +  G  G  G  G  G RG PG PG PGS  K   
Sbjct: 495  GPNGIPGEKGPAGERGAPGPAGPRGAA-GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553

Query: 1554 HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGE 1613
             G +G +G  G  G  GP G  G +G  GP+G  G  G  GE+GG G  GPQGPPG  GE
Sbjct: 554  PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613

Query: 1614 AGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGF 1669
             G QG  G  G    PG  G+KG  G PGP+GLQG  G+ G     G  G  G KG  G 
Sbjct: 614  TGPQGPPGPTG----PG--GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA 667

Query: 1670 PGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG  G KG+ G PG  G  GL GA G    AG PG  G  G  GPPG  G  G  GL
Sbjct: 668  PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724



 Score =  262 bits (670), Expect = 2e-69
 Identities = 166/383 (43%), Positives = 186/383 (48%), Gaps = 52/383 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG  G+RG PG  G +G  G+ G  G +G PGP G  G KG  G  GP+G +
Sbjct: 582  GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ 641

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G  G  GENG  G  G +GD G PG  G KGD G+   PG+RG PG  GA GLRG  
Sbjct: 642  GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA---PGERGPPGLAGAPGLRGGA 698

Query: 1512 GAPGVDS-----------SIEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKTAAH 1554
            G PG +               G  GL+G  G +G  G PGP      PG PG+       
Sbjct: 699  GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD 758

Query: 1555 GRRGHTGP------------------QGTAGIPGPDGLEGSLGLKGPQGP---------R 1587
            G RG TGP                   G  GI GP G  G  G  GP GP          
Sbjct: 759  GPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQN 818

Query: 1588 GEAGVKGEKGGVGSKGPQGPP---GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
            GE G KGE+G  G KG  GPP   GP G +G  G  G QG KGE G  G  GA GFPG R
Sbjct: 819  GEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGAR 878

Query: 1645 GLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPG 1704
            GL G  GS   G+ G  G  G  G  G  GP G  G PG PG +G KG  G+    G PG
Sbjct: 879  GLPGPPGS--NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936

Query: 1705 EMGSPGEPGPPGRKGVKGAKGLA 1727
              G PG PGP G  G+ GA+GLA
Sbjct: 937  AQGPPGAPGPLGIAGITGARGLA 959



 Score =  262 bits (670), Expect = 2e-69
 Identities = 154/380 (40%), Positives = 184/380 (48%), Gaps = 33/380 (8%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ GPPG  GPPG  G  G  G +G+ GERG+PG  G  G  G  G  GP G+ 
Sbjct: 828  GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887

Query: 1452 GLNGQEGEVGENGID---------------GLNGEQGDNGLPGRKGEKGDEGSQGSPGKR 1496
            G  G  G  G  G D               G++G +GD G PG KG  G +G  G+PG  
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 1497 GTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR 1556
            G  G  GA+GL G PG PG   S  GP G+KGE G+ G  G  G  G PG +      G 
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGS-PGPQGVKGESGKPGANGLSGERGPPGPQ---GLPGL 1003

Query: 1557 RGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGN 1616
             G  G  G  G PG DGL G  G  G +G RGE G  G  G  G  GP GP GP G++G+
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD 1063

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSV-GRKGAKGQEGFPGESGP 1675
            +G  G  G  G PG  G +GA G  GPRG +G  G  G   + G +G  G  G PG  GP
Sbjct: 1064 RGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGP 1123

Query: 1676 KGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELI 1735
             G+ G  G PG  G +G  G     G  G  G PG  GPPG +G +G +G          
Sbjct: 1124 AGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERG---------- 1173

Query: 1736 QYVRDRSPGRHGKPECPVHP 1755
                + SPG  G+P  P  P
Sbjct: 1174 ---SEGSPGHPGQPGPPGPP 1190



 Score =  261 bits (667), Expect = 6e-69
 Identities = 163/385 (42%), Positives = 188/385 (48%), Gaps = 57/385 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG----- 1446
            G  G MG  G PG+RG PG  G+ G  G +G  G  G PGP G  GT G  G+ G     
Sbjct: 294  GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 1447 -PKGNRGLNGQEGEVGENGIDGLNGEQGD------NGLPGRKGEKGDEGSQGSP---GKR 1496
             P G+ G NG  G+ GE G  G  G QG       NG PG KGE G  G  G+P   G R
Sbjct: 354  GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 1497 GTPGD---RGAKGLRGDPGAPGV--------------DSSIEGPTGLKGERGRQGRRGWP 1539
            G PG     GA GLRG  G PG               ++ I G  G KGE G+ G  G P
Sbjct: 414  GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 1540 GPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGV 1599
            G  G PG+  +  A G RG  GP G  G  GP G  G+ G  GP+G  GE G  G  GG 
Sbjct: 474  GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 1600 GSKGPQGPPGPGGEAGNQGRLGSQGNKGEP------GDLGEKGAVGFPGPRGLQGNDGSP 1653
            G +G  G PG  G  G  G  GSQG  G P      G  G+ G +GFPGP+   GNDG+P
Sbjct: 534  GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK---GNDGAP 590

Query: 1654 G-------------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISA 1700
            G              G  G+ G  G +G PG +GP G+ GD G PG  GL+G  G   + 
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG---TG 647

Query: 1701 GLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G PGE G PGEPGP G  G  GA G
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPG 672



 Score =  256 bits (654), Expect = 2e-67
 Identities = 154/369 (41%), Positives = 170/369 (46%), Gaps = 21/369 (5%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G PG  G+ G PG  G  G  G  G  GE G PGP G  G  G  G  G KG 
Sbjct: 767  IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
            RG  G++GE G  G+ G  G  G  G PG +G KG+ GS G PG  G PG RG  G  G 
Sbjct: 827  RGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS 886

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             G PG      G  G  G  G  G  G PG PG  G +      G +G  G QG  G PG
Sbjct: 887  NGNPGPPGP-SGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPG 1630
            P G+ G  G +G  GP G  G +G  G  G KG  G PG  G +G +G  G QG  G  G
Sbjct: 946  PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 1631 DLGEKGAVGFPGPRGLQGNDGSPG-------YGSVGRKGAKGQEGFPGESGPKGEIGDPG 1683
              GE G  G PG  GL G DGSPG        GS G  GA G  G PG  GP G+ GD G
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 1684 GPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSP 1743
              G  G  GA G   S G PG  G  G+ G  G +G  G KG   F             P
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGF-------------P 1112

Query: 1744 GRHGKPECP 1752
            G  G P  P
Sbjct: 1113 GNPGAPGSP 1121



 Score =  255 bits (651), Expect = 4e-67
 Identities = 164/428 (38%), Positives = 194/428 (45%), Gaps = 81/428 (18%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G MG  GPPG  G  G  G  G  GE G  G +G PGP GE+G  G  G  G KG  
Sbjct: 405  GAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGED 464

Query: 1452 GLNGQEGEVGENGIDGLNGEQG---------DNGLPGRKGEKGDEGSQG---------SP 1493
            G +G  GE G NG+ G  GE+G          NG+PG KG  G+ G+ G          P
Sbjct: 465  GKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP 524

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGR------QGRRGWPGPPGTPGS 1547
            G+ G PG  G +G+ G PG PG D    GP G +GE GR       G RG PG  G PG 
Sbjct: 525  GRDGVPGGPGMRGMPGSPGGPGSDGK-PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583

Query: 1548 RRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGP 1607
            +    A G+ G  G  G  G  GP G  G  G +GP GP G  G KG+ G  G +G QG 
Sbjct: 584  KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL 643

Query: 1608 PGPGGEAGNQGRLGSQGNKGE---PGDLGEKGAVGFPGPRGLQGNDGSPGY--------- 1655
            PG GG  G  G+ G  G KG+   PG  G KG  G PG RG  G  G+PG          
Sbjct: 644  PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703

Query: 1656 ----------GSVGRKGAKGQEGFPGESG------PKGEIGDPGGPGETGLKGA---RGK 1696
                      G  G  G  G +G PGE G      PKG+ G+PGGPG  G+ G    RG 
Sbjct: 704  EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGP 763

Query: 1697 MISAGLPGEMGSPGEPGP---------------PGRKGVKGAKGLASFSTCELIQYVRDR 1741
                G PG  G PG+ G                PG +G  G  G A F            
Sbjct: 764  TGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF----------PG 813

Query: 1742 SPGRHGKP 1749
            +PG++G+P
Sbjct: 814  APGQNGEP 821



 Score =  254 bits (648), Expect = 9e-67
 Identities = 155/385 (40%), Positives = 184/385 (47%), Gaps = 51/385 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGS---EGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G PG  G+RG PGF+G     G  GE+G AGERGAPGP G +G  G  G  G  
Sbjct: 471  GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL- 1507
            G  G+ G  G  G  G DG  G  G  G  GR G  G  G +G PG  G PG +G  G  
Sbjct: 531  GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 1508 -----RGDPGAPGV--------DSSIEGPTGLKGERGRQGRRGWPGPPGT---PGSRRKT 1551
                 RG PG PG         ++  +GP G  G  G +G  G PGP G    PG+    
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGP---------RGEAGVKGEKGGVGSK 1602
              +G+ G  GP+G AG PG  G +G  G  G +GP         RG AG  G +GG G+ 
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710

Query: 1603 GPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-------Y 1655
            GP GPPG  G  G QG  G +G  G PG  G+KG  G PG  G+ G DG  G        
Sbjct: 711  GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 1656 GSVGRKGAKGQEGFP---------------GESGPKGEIGDPGGPGETGLKGARGKMISA 1700
            G  G+ G KG+ G P               GE+GP G  G PG PG+ G  G +G+  + 
Sbjct: 771  GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 1701 GLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G  GE G PG  GPPG  G  G  G
Sbjct: 831  GEKGEGGPPGVAGPPGGSGPAGPPG 855



 Score =  252 bits (643), Expect = 3e-66
 Identities = 148/339 (43%), Positives = 171/339 (50%), Gaps = 23/339 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGPPG  G PG  GS GY G  G  G+ G  GP G  G  G  G  G  G  
Sbjct: 174  GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G+ GE G  G  G+ G  G  G PG KG +G +G  G  G+ G PG +G  GL G+ 
Sbjct: 234  GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            GAPG      GP G  GERGR         PG PG      A G RG+ G +G+ G PGP
Sbjct: 294  GAPGP----MGPRGAPGERGR---------PGLPG------AAGARGNDGARGSDGQPGP 334

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G  G+ G  G  G +GE G  G  G  G+ G +G PGP G AG QG  G  G  G PG 
Sbjct: 335  PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL 1690
             GE G  G PG  GL G  G PG  G+ G  G +G  G PG++G KGE G  G  GE G+
Sbjct: 395  KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
             G  G   + G  G+ GSPGEPG  G  G  G +G   F
Sbjct: 455  PGVPG---AKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490



 Score =  249 bits (635), Expect = 3e-65
 Identities = 153/370 (41%), Positives = 181/370 (48%), Gaps = 36/370 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGA---PGPVGEQGTKG---CYGTK 1445
            G  G +G PGP G +G PG  G++G  G++G  G  G    PGP G+ G KG     G  
Sbjct: 729  GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQ------------GSP 1493
            G  G RG  G+ GE G  G  G  G  G NG PG KGE+G  G +            G  
Sbjct: 789  GIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGS 848

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDS-----SIEGPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G PG +G KG RG PG PG         + GP G  G  G  G  G PG  G PG  
Sbjct: 849  GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908

Query: 1549 RKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEK---GGVGSKGPQ 1605
              T A G  G +GP+G AG PG  G  G+ G  G  GP G AG+ G +   G  G  GP+
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 1606 GPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-------GSV 1658
            G PGP G  G  G+ G+ G  GE G  G +G  G  G  G  G DG+PG        GS 
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028

Query: 1659 GRKGAKGQEGFPGESGPKGEIGDPG--GP-GETGLKGARGKMISAGLPGEMGSPGEPGPP 1715
            G KG +G+ G PG  G  G  G PG  GP G++G +G  G    AG PG  GS G PGP 
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088

Query: 1716 GRKGVKGAKG 1725
            G +G KG  G
Sbjct: 1089 GPRGDKGETG 1098



 Score =  240 bits (613), Expect = 1e-62
 Identities = 142/321 (44%), Positives = 160/321 (49%), Gaps = 13/321 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGP G  G PG  G  G  G+ G  GE+G+PG  G  G  G  G  G  G R
Sbjct: 897  GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKG---EKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            GL G  G  G  G  G  G +G++G PG  G   E+G  G QG PG  GT G+ G  G  
Sbjct: 957  GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G  G PG D S  G  G +GE G  G  G PG PG PG        G RG +GP G AG 
Sbjct: 1017 GSDGLPGRDGS-PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
            PGP    GS G  GPQGPRG+ G  GE+G  G KG +G PG  G  G+ G  G QG  G 
Sbjct: 1076 PGP---AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132

Query: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
            PG  G +G VG  GP G  G  G PG     G  G +G +G EG PG  G  G  G PG 
Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192

Query: 1685 PGETGLKGARGKMISAGLPGE 1705
            PG     G  G    AG+ GE
Sbjct: 1193 PGP--CCGGVGAAAIAGIGGE 1211



 Score =  193 bits (490), Expect = 2e-48
 Identities = 138/390 (35%), Positives = 157/390 (40%), Gaps = 92/390 (23%)

Query: 1447 PKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEG------------------ 1488
            P   +G  G +G+ G  GI G NG+ G  G PG  G  G  G                  
Sbjct: 98   PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157

Query: 1489 -----------------------------------SQGSPGKRGTPGDRGAKGLRGDPGA 1513
                                               S GSPG +G PG+ G  G  G PG 
Sbjct: 158  YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217

Query: 1514 PGVDSSIEGPTGLKGERGRQGR---RGWPGPPGT---------PGSRRKTAAHGRRGHTG 1561
            PG      GP G  GE GR GR   RG PGPPG          PG +      GR G  G
Sbjct: 218  PGAIGP-SGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 1562 PQGTAGIPGPDGLEGSLGLKGPQGPR------------GEAGVKGEKGGVGSKGPQGPPG 1609
              G  G+ G +GL G  G  GP GPR            G AG +G  G  GS G  GPPG
Sbjct: 277  ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336

Query: 1610 PGGEAGNQGRLGSQGN---KGEPGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKG 1662
            P G AG  G  G++G     G PG  G  G  G PGP+G  G  G PG     GS G KG
Sbjct: 337  PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396

Query: 1663 AKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
              G  G PG  G  G  G PG  G  G  G RG    AG PG+ G+ GEPGP G +G  G
Sbjct: 397  EMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG---GAGEPGKNGAKGEPGPRGERGEAG 453

Query: 1723 AKGLASFSTCELIQYVRDRSPGRHGKPECP 1752
              G+         +  +D SPG  G    P
Sbjct: 454  IPGVPGAKG----EDGKDGSPGEPGANGLP 479



 Score =  152 bits (385), Expect = 3e-36
 Identities = 101/278 (36%), Positives = 119/278 (42%), Gaps = 58/278 (20%)

Query: 1523 PTGLKGERGRQGRRGWPGPPGTPGS----------------------------------- 1547
            PT     +G QG +G PGPPG PG                                    
Sbjct: 95   PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154

Query: 1548 ------RRKTAAHGRRGHTGPQGTAGIPGPDGLE------GSLGLKGPQGPRGEAGVKGE 1595
                  +   A  G  G+ GP G  G PGP G        GS G +GP G  G+AG  G 
Sbjct: 155  YDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP 214

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG- 1654
             G  G+ GP GP G  GE+G  GR G +G  G PG  G  G  GFPG +G +G DG  G 
Sbjct: 215  PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGE 274

Query: 1655 YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE---TGLKGARGKMISAGLPGEMGSPGE 1711
             G  G  G KG+ G PGE+G  G +G  G PGE    GL GA G   + G  G  G PG 
Sbjct: 275  KGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGP 334

Query: 1712 PGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKP 1749
            PGPPG  G  G+ G          +     SPG +G P
Sbjct: 335  PGPPGTAGFPGSPGAKG-------EVGPAGSPGSNGAP 365



 Score =  102 bits (255), Expect = 3e-21
 Identities = 65/170 (38%), Positives = 73/170 (42%), Gaps = 6/170 (3%)

Query: 1562 PQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGG-----EAGN 1616
            PQ       P   +G  G KG  GP G  G  G+ G  G  G  G PGP G       G 
Sbjct: 89   PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGP 1675
            Q       +      +   G  G+PGP G  G  G PG  G  G  G+ G +G PGE G 
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 1676 KGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G  G PG PG  G  G  GK   +G PG  G  G PGPPG KG  G  G
Sbjct: 209  AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPG 258



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 59/145 (40%), Positives = 71/145 (48%), Gaps = 9/145 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  G PG +GP G KG  G  G  GI G RG PG  G  G+ G  G +G  G+ 
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133

Query: 1452 GLNGQEGEVGENGI---DGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G  G  G VG +G    DG +G  G  G PG +G +G+ GS+GSPG  G PG  G     
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP---- 1189

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQ 1533
              PGAPG      G   + G  G +
Sbjct: 1190 --PGAPGPCCGGVGAAAIAGIGGEK 1212



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 56/164 (34%), Positives = 65/164 (39%), Gaps = 31/164 (18%)

Query: 1604 PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG--------- 1654
            PQ P  P      QG  G +G+ G PG  G  G  G PG  G  G+ G PG         
Sbjct: 89   PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 1655 ------YGSVGRK---GAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGE 1705
                  Y S   K      G  G+PG +GP G  G PG  G  G  G+ G     G PG+
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 1706 MGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKP 1749
             G  G PGPPG  G  G  G             +D   GR G+P
Sbjct: 209  AGPSGPPGPPGAIGPSGPAG-------------KDGESGRPGRP 239



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 36/89 (40%), Positives = 42/89 (47%), Gaps = 1/89 (1%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  GP G  GPPG  G+ G+ G  G  G RG  G  G +G+ G  G  GP G 
Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189

Query: 1451 RGLNGQ-EGEVGENGIDGLNGEQGDNGLP 1478
             G  G   G VG   I G+ GE+     P
Sbjct: 1190 PGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  275 bits (703), Expect = 4e-73
 Identities = 160/355 (45%), Positives = 185/355 (52%), Gaps = 23/355 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKG---SEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G PGPPG  GP G  G   ++G  G  G AGERG  GP G  G +G  G  GP 
Sbjct: 593  GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G  G  G++G  G+ G  G +G +G+ G PG +G +G  G  G  G  G PG+ GAKG  
Sbjct: 653  GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G PGAPG     +G  GL+G  G +G  G PGP G  G      A G  G  G +G  G 
Sbjct: 713  GAPGAPGS----QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
             GP G  G+ G KG  GP G AG  G +G  G +G  GPPGP G AG  G  G  G KGE
Sbjct: 769  IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828

Query: 1629 PGDLGEKGAVGFPGPRGLQ------GNDGSPGY----------GSVGRKGAKGQEGFPGE 1672
            PGD G KG  G PGP G        GN G+PG           G+ G  GA G+ G PG 
Sbjct: 829  PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888

Query: 1673 SGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            SG  G  G PG  G+ G KG RG+   AG PGE+G PG PGP G KG  GA G A
Sbjct: 889  SGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA 943



 Score =  273 bits (697), Expect = 2e-72
 Identities = 156/358 (43%), Positives = 183/358 (51%), Gaps = 27/358 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVG---EQGTKGCYGTKGPK 1448
            G  G  G PGP G  GPPGF G+ G  GE G  G RG+ GP G   E G  G  G  GP 
Sbjct: 326  GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPA 385

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            GN G +GQ G  G NG  G+ G  G    PG +G  G +G  G PG +G  G+ GA G +
Sbjct: 386  GNPGADGQPGAKGANGAPGIAGAPG---FPGARGPSGPQGPGGPPGPKGNSGEPGAPGSK 442

Query: 1509 GDPGAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTA 1566
            GD GA G      ++GP G  GE G++G RG PGP G PG   +    G RG  G  G A
Sbjct: 443  GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA 502

Query: 1567 GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG---PQGPPGPGGEAGNQGRLGSQ 1623
            G  GP G  GS G  GP+G  GEAG  GE G  G+KG     G PGP G+ G  G  G  
Sbjct: 503  GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 1624 GNKGEPGD---LGEKGAVGFPGPRGLQGNDGSPG----------YGSVGRKGAKGQEGFP 1670
            G  G PG     G+ G +GFPGP+G  G  G  G           G  G+ G  G +G P
Sbjct: 563  GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622

Query: 1671 GESGP---KGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G +GP   +GE G  G PG  GL G  G    AG PGE G PG+ G PG  G +G +G
Sbjct: 623  GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG 680



 Score =  266 bits (681), Expect = 1e-70
 Identities = 162/375 (43%), Positives = 186/375 (49%), Gaps = 41/375 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKG------SEGYLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G  G PGPPG  GPPG  G      S GY  +E   G    PGP+G  G +G  G  
Sbjct: 136  GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGY--DEKSTGGISVPGPMGPSGPRGLPGPP 193

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  G +G  G  GE GE G  G  G +G  G PG+ G+ G+ G  G PG+RG PG +GA+
Sbjct: 194  GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253

Query: 1506 GLRGDPGAPGVD-----SSIEG------PTGLKGE---------------RGRQGRRGWP 1539
            GL G  G PG+      S ++G      P G KGE               RG  G RG P
Sbjct: 254  GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313

Query: 1540 GPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGV 1599
            G PG  G+R    A G  G  GP G AG PG  G  G+ G  GPQGPRG  G +G +G  
Sbjct: 314  GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP 373

Query: 1600 GSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----Y 1655
            G  GP G  GP G  G  G+ G++G  G PG  G  G  G  GP G QG  G PG     
Sbjct: 374  GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 1656 GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGL---PGEMGSPGEP 1712
            G  G  G+KG  G  GE GP G  G PG  GE G +GARG+    GL   PGE G PG  
Sbjct: 434  GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493

Query: 1713 GPPGRKGVKGAKGLA 1727
            G PG  GV G KG A
Sbjct: 494  GFPGADGVAGPKGPA 508



 Score =  266 bits (680), Expect = 2e-70
 Identities = 161/389 (41%), Positives = 189/389 (48%), Gaps = 48/389 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERG---APGPVGEQGTKGCYGTKGPK 1448
            G  G  G  GP G+ G PG  G+ G +G  G+ GERG   APGP G +G  G  G  GP 
Sbjct: 275  GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 1449 GNRG---------LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTP 1499
            G  G           G +GE G  G  G  G QG  G PG  G  G  G  G+PG  G P
Sbjct: 335  GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            G +GA G  G  GAPG   +  GP+G +G  G  G +G  G PG PGS+  T   G +G 
Sbjct: 395  GAKGANGAPGIAGAPGFPGA-RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT---GAKGE 450

Query: 1560 TGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG---PQGPPGPGGEAGN 1616
             GP G  G PGP G EG  G +G  GP G  G  GE+GG GS+G     G  GP G AG 
Sbjct: 451  PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE 510

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----------------YGSVGR 1660
            +G  G  G KG PG+ G  G  G PG +GL G+ GSPG                 G  G 
Sbjct: 511  RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570

Query: 1661 KGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGV 1720
             GA+GQ G  G  GPKG  G+PG  GE G+ G  G +  AG  GE G+ G PGP G  G 
Sbjct: 571  PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630

Query: 1721 KGAKGLASFSTCELIQYVRDRSPGRHGKP 1749
            +G +G A              SPG  G P
Sbjct: 631  RGEQGPAG-------------SPGFQGLP 646



 Score =  265 bits (676), Expect = 5e-70
 Identities = 160/365 (43%), Positives = 181/365 (49%), Gaps = 42/365 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPV---------GEQGTKGCY 1442
            G DG  G  GPPG  GP G +G +G  G  G    +G PGP          GEQG  G  
Sbjct: 611  GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF---QGLPGPAGPPGEAGKPGEQGVPGDL 667

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGD------EGSQGSPGKR 1496
            G  GP G RG  G  GE G  G  G  G +G NG PG  G KGD       GSQG+PG +
Sbjct: 668  GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ 727

Query: 1497 GTPGDRGAKGL------RGDPGAPGVDSS--------IEGPTGLKGERGRQGRRGWPGPP 1542
            G PG+RGA GL      RGD G  G D S        + GP G  G  G  G +G  GP 
Sbjct: 728  GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS 787

Query: 1543 GTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
            G  G      A G RG  GP G AG  GP G +G  G KG     G+AG KG+ G  G  
Sbjct: 788  GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP---GDAGAKGDAGPPGPA 844

Query: 1603 GPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRK 1661
            GP GPPGP G  G  G  G++G+ G PG  G  GA G  GP G  GN G PG  G  G++
Sbjct: 845  GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904

Query: 1662 GAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVK 1721
            G KG  G  G +G  GE+G PG PG  G KG      S G  G  G+PG PGP G  G +
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKG------SPGADGPAGAPGTPGPQGIAGQR 958

Query: 1722 GAKGL 1726
            G  GL
Sbjct: 959  GVVGL 963



 Score =  264 bits (674), Expect = 8e-70
 Identities = 158/379 (41%), Positives = 177/379 (46%), Gaps = 45/379 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYG------TK 1445
            G  G  G+PGP G +GPPG  G EG  G  G  G  G PGP GE+G  G  G        
Sbjct: 443  GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA 502

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GPKG  G  G  G  G  G  G  G  G+ GLPG KG  G  GS G  GK G PG  G  
Sbjct: 503  GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 1506 GLRGDPGAPGVDSS-----IEGPTGLKGERGRQGRRGWPGPPGTPGSRRK---TAAHGRR 1557
            G  G PG PG           GP G  GE G+ G RG PGPPG  G   K     A G  
Sbjct: 563  GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEA------------------GVKGEKGGV 1599
            G  GP G  G  GP G  G  GL GP GP GEA                  G +GE+G  
Sbjct: 623  GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP 682

Query: 1600 GSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY---- 1655
            G +G QGPPGP G  G  G  G+ G KG+ G  G  G+ G PG +G+ G  G+ G     
Sbjct: 683  GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742

Query: 1656 GSVGRKGAKGQEGFPGES---------GPKGEIGDPGGPGETGLKGARGKMISAGLPGEM 1706
            G  G  G KG +G PG+          GP G  G PG  GE+G  G  G   + G PG+ 
Sbjct: 743  GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802

Query: 1707 GSPGEPGPPGRKGVKGAKG 1725
            G PG PGP G  G  GA G
Sbjct: 803  GEPGPPGPAGFAGPPGADG 821



 Score =  263 bits (671), Expect = 2e-69
 Identities = 162/389 (41%), Positives = 190/389 (48%), Gaps = 54/389 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIA---GERGAPGPVGEQGTKGCYGTKGP 1447
            +G  G  G PGPPG  GP GF+G  G  GE G +   G RG PGP G+ G  G  G  G 
Sbjct: 181  MGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGR 240

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGD------EGSQGSPGKRGTPGD 1501
             G RG  G +G  G  G  GL G +G  G  G  G KGD      +G  GSPG+ G PG 
Sbjct: 241  PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ 300

Query: 1502 RGAKGL---RGDPGAPGVDSS--IEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR 1556
             G +GL   RG PGAPG   +   +G TG  G  G  G  G PG PG  G++ +    G 
Sbjct: 301  MGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP 360

Query: 1557 RGHTGPQGTAGIPGP---------------DGLEGSLGLKGPQGPRGEAGVKGEKGGVGS 1601
            RG  GPQG  G PGP               DG  G+ G  G  G  G  G  G +G  G 
Sbjct: 361  RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP 420

Query: 1602 KGPQGPPGPGGEAGNQGRLGSQGN---KGEPGDL------------------GEKGAVGF 1640
            +GP GPPGP G +G  G  GS+G+   KGEPG +                  GE G  G 
Sbjct: 421  QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480

Query: 1641 PGPRGLQGNDGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGK 1696
            PGP G +G  GS G+    G  G KG  G+ G PG +GPKG  G+ G PGE GL GA+G 
Sbjct: 481  PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540

Query: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              S G PG  G  G PGP G+ G  G  G
Sbjct: 541  TGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569



 Score =  254 bits (650), Expect = 5e-67
 Identities = 157/376 (41%), Positives = 179/376 (47%), Gaps = 46/376 (12%)

Query: 1392 GGDGTMGDPGPPGKRGP---PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G PGP G RG    PG  G++G  G  G  G +GAPG  G  G +G  G  GPK
Sbjct: 683  GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G+RG  G +G  G  G DG+ G  G  G PG  G  GD+G  G  G  G  G RGA G R
Sbjct: 743  GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802

Query: 1509 GDPGAPGVDSSIEGP---------------TGLKGERGRQGRRGWPGPPGTPGSRRKTAA 1553
            G+PG PG  +   GP                G KG+ G  G  G  GPPG  G+     A
Sbjct: 803  GEPGPPG-PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861

Query: 1554 HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGE 1613
             G RG  GP G  G PG  G  G  G  G  GP G  G  G++GG G +G  GP G  GE
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921

Query: 1614 AGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGES 1673
             G  G  G  G KG PG  G  GA G PGP+G+ G       G VG  G +G+ GFPG  
Sbjct: 922  VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQ-----RGVVGLPGQRGERGFPGLP 976

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCE 1733
            GP GE   PG  G +G  G RG       PG MG PG  GPPG  G +GA G        
Sbjct: 977  GPSGE---PGKQGPSGASGERGP------PGPMGPPGLAGPPGESGREGAPG-------- 1019

Query: 1734 LIQYVRDRSPGRHGKP 1749
                  + SPGR G P
Sbjct: 1020 -----AEGSPGRDGSP 1030



 Score =  250 bits (639), Expect = 1e-65
 Identities = 144/326 (44%), Positives = 164/326 (50%), Gaps = 14/326 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G +G PGP G  GPPG     G  G+EG  G RG  GP G  G  G  G  GP G +
Sbjct: 878  GAAGRVGPPGPSGNAGPPG---PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G  G  G  G  G  G  G+ G  G++G+ G  G PG  G PG +G  G  G+ 
Sbjct: 935  GSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER 994

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG      GP GL G  G  GR G PG  G+PG      A G RG TGP G  G P  
Sbjct: 995  GPPGP----MGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-- 1048

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
                G+ G  GP GP G++G +GE G  G  GP GP G  G AG QG  G +G  GE GD
Sbjct: 1049 ----GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD 1104

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL 1690
             G KG  GF G +G  G  GSPG  G  G  G  G  G PG +G  G+ G  G PG  G 
Sbjct: 1105 RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGP 1164

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPG 1716
             G RG+   AG  G  G PG PGPPG
Sbjct: 1165 PGPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score =  250 bits (638), Expect = 1e-65
 Identities = 149/344 (43%), Positives = 170/344 (49%), Gaps = 11/344 (3%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GD GPPG  GP G  G  G +G  G  G RG+ GP G  G  G  G  GP G  
Sbjct: 830  GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  G  G +G  G +G+ G  GR GE G  G  G  G++G+PG  G  G  G P
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G  G+     G  GL G+RG +G  G PGP G PG +  + A G RG  GP G  G+ GP
Sbjct: 950  GPQGIAGQ-RGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPG----PG--GEAGNQGRLGSQGN 1625
             G  G  G  G +G  G  G  G KG  G  GP GPPG    PG  G  G  G+ G +G 
Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGE 1068

Query: 1626 KGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPG- 1683
             G  G  G  G VG  GP G QG  G  G  G  G +G KG  GF G  GP G  G PG 
Sbjct: 1069 TGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGE 1128

Query: 1684 -GP-GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             GP G +G  G RG   SAG PG+ G  G PGP G  G +G  G
Sbjct: 1129 QGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTG 1172



 Score =  243 bits (620), Expect = 2e-63
 Identities = 163/408 (39%), Positives = 182/408 (44%), Gaps = 72/408 (17%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGI---AGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  G PGP G RG  G KG++G  G++G+    G  G PGP G  G KG  G  GP 
Sbjct: 731  GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790

Query: 1449 GN---RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G    RG  G  GE G  G  G  G  G +G PG KGE GD G++G  G  G  G  G  
Sbjct: 791  GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850

Query: 1506 GLRGDPGAPGVDSS--IEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKTAAHGRR 1557
            G  G+ GAPG   +    GP G  G  G  GR G PGP      PG PG   K    G R
Sbjct: 851  GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPR 910

Query: 1558 GHTGPQGTAG---------------IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
            G TGP G  G                PG DG  G+ G  GPQG  G+ GV G  G  G +
Sbjct: 911  GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970

Query: 1603 GPQGPPGPGGEAGNQGRLGSQGNKGEPGDLG---------EKGAVGFPGPRGLQGNDGSP 1653
            G  G PGP GE G QG  G+ G +G PG +G         E G  G PG  G  G DGSP
Sbjct: 971  GFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP 1030

Query: 1654 GY-------GSVGRKGAKGQEGFPGESGPKGEIGD-----PGGP---------------- 1685
            G        G  G  GA G  G PG  GP G+ GD     P GP                
Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQ 1090

Query: 1686 ------GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
                  GETG +G RG     G  G  G PG PG PG +G  GA G A
Sbjct: 1091 GPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPA 1138



 Score =  209 bits (532), Expect = 2e-53
 Identities = 126/309 (40%), Positives = 144/309 (46%), Gaps = 41/309 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGPPG  G  G KG  G  G  G  GE G PGP G  G KG  G  GP G  
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNG---LPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G  G +G  G+ G+ GL G++G+ G   LPG  GE G +G  G+ G+RG PG  G  GL 
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 1509 GDPG------APGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHT 1560
            G PG      APG + S   +G  G KG+RG  G  G PG PG PG+       G+ G  
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066

Query: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG----------------- 1603
            G  G AG  GP G  G+ G  GPQGPRG+ G  GE+G  G KG                 
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 1604 -------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
                         P+GPPG  G  G  G  G  G  G PG  G  G  G  GP G  G  
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 1651 GSPGYGSVG 1659
            G PG  S G
Sbjct: 1187 GPPGPPSAG 1195



 Score =  191 bits (485), Expect = 7e-48
 Identities = 124/321 (38%), Positives = 140/321 (43%), Gaps = 45/321 (14%)

Query: 1438 TKGCYGTKGPKGNRGLNGQEGEVG--ENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK 1495
            TK C G + P+G       +G     +    G+ G +GD G  G +G  G  G  G PG+
Sbjct: 78   TKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQ 137

Query: 1496 RGTPGDRGAKGLRGDPG-----AP----GVDSSIEGPTGLKGERGRQGRRGWPGPPGTPG 1546
             G PG  G  G  G PG     AP    G D    G   + G  G  G RG PGPPG PG
Sbjct: 138  PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPG 197

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQG 1606
             +            G QG  G PG  G  G +G +GP GP G+ G  GE G  G  G +G
Sbjct: 198  PQ------------GFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERG 245

Query: 1607 PPGPGGEA---------------------GNQGRLGSQGNKGEPGDLGEKGAVGFPGPRG 1645
            PPGP G                       G +G  G  G KGEPG  GE GA G  GPRG
Sbjct: 246  PPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305

Query: 1646 LQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPG 1704
            L G  G PG  G  G +G  G  G  G  GP G  G PG PG  G KG  G     G  G
Sbjct: 306  LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEG 365

Query: 1705 EMGSPGEPGPPGRKGVKGAKG 1725
              G  GEPGPPG  G  G  G
Sbjct: 366  PQGVRGEPGPPGPAGAAGPAG 386



 Score =  152 bits (384), Expect = 4e-36
 Identities = 90/220 (40%), Positives = 101/220 (45%), Gaps = 28/220 (12%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG  G+ G PG +GS G  G  G  G+RG  GP G  G  G  G  GP G 
Sbjct: 1000 MGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP 1059

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
             G +G  GE G  G  G  G  G  G  G +G +GD+G  G  G RG  G RG  GL+G 
Sbjct: 1060 AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGP 1119

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
            P          GP G  GE+G  G  G  GP G PGS          G  G  G  G+PG
Sbjct: 1120 P----------GPPGSPGEQGPSGASGPAGPRGPPGS---------AGAPGKDGLNGLPG 1160

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGP 1610
            P G         P GPRG  G  G  G  G  GP GPPGP
Sbjct: 1161 PIG---------PPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191



 Score =  127 bits (318), Expect = 2e-28
 Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 12/195 (6%)

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGS 1622
            Q T G+ GP G  G  G +GP GP G  G+ G+ G  G  GP GPPGP G  GN     S
Sbjct: 105  QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLS 164

Query: 1623 QG-NKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGD 1681
             G ++   G +   G +G  GPRGL G  G+PG    G +G  G+ G PG SGP G  G 
Sbjct: 165  YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPG--PQGFQGPPGEPGEPGASGPMGPRGP 222

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGP---PGRKGVKGAKGLASFSTCELIQYV 1738
            PG PG+ G  G  GK    G PGE G PG  G    PG  G+ G KG   FS  +  +  
Sbjct: 223  PGPPGKNGDDGEAGK---PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAK-- 277

Query: 1739 RDRSP-GRHGKPECP 1752
             D  P G  G+P  P
Sbjct: 278  GDAGPAGPKGEPGSP 292


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  275 bits (703), Expect = 4e-73
 Identities = 153/343 (44%), Positives = 185/343 (53%), Gaps = 6/343 (1%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PGPPG  G PG +G  G  G  GI G  G  GP G  G KG  G KGP+G 
Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGP 1130

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
             G +G +G VG  G  G  G  G++G  G  GE G +GS+G  G++G PG  G +G  G 
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 1511 PGAPGVDSSI--EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            PG  G D      G  GL G++G +G RG+PGPPG  G +      G +G TG  G  G 
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
            PGP G  G  G  G  GP+G  G  G  G VG KG  G  G  G  G  G  G +G +GE
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE 1310

Query: 1629 PGDLGEKGAVGFPGPRGLQGND---GSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             G+ G  GA G PGP+G  G+D   GSPG  G  G  G  G+ G  G+ GP G+ GD G 
Sbjct: 1311 KGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGE 1370

Query: 1685 PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            PG+TG  G  G+   +G PG+ G PG  GP GR+G KGAKG A
Sbjct: 1371 PGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413



 Score =  269 bits (688), Expect = 2e-71
 Identities = 159/373 (42%), Positives = 189/373 (50%), Gaps = 45/373 (12%)

Query: 1392 GGDGTMGDPGPPGKRGP---------------PGFKGSEGYLGEEGIAGERGAPGPVGEQ 1436
            GG GT G PGP G+RGP               PG KG+ G  G  G  GERG  GP G  
Sbjct: 898  GGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPT 957

Query: 1437 GTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGE---------QGDNGLPGRKGEKGDE 1487
            G  G  G  GP G  GL G  G+ GE G  G  G          QG  G  G  GE+G  
Sbjct: 958  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHP 1017

Query: 1488 GSQGSPGKRGTPGDRGAKGLRGDPGAPGV--------------DSSIEGPTGLKGERGRQ 1533
            G  G PG++G PG  G +G +GDPG  G+              D  + GP G  G +G +
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077

Query: 1534 GRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVK 1593
            G  G PGP G+PG R    A G  G  G  G  G PGP G +G+ G KGPQGP G  G++
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 1594 GEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSP 1653
            G    VG  GP GP GP GE G++G +G  G KG  GD GE+G    PGP G QG  G P
Sbjct: 1138 GP---VGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGP---PGPTGPQGPIGQP 1191

Query: 1654 G-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEP 1712
            G  G+ G  G +GQ+G  G+ G +G  G PG PG  GL+G  G     G  G++G  G P
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251

Query: 1713 GPPGRKGVKGAKG 1725
            GPPG +G  GA G
Sbjct: 1252 GPPGPRGPSGAPG 1264



 Score =  266 bits (680), Expect = 2e-70
 Identities = 155/361 (42%), Positives = 178/361 (49%), Gaps = 30/361 (8%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPG +GP G+ G  G  G +GI G +G  G  GE G  G  G  G KG+R
Sbjct: 769  GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G  GE+G +G  G  G NG PG  G  G++G  G PG  G PG +G KG  G P
Sbjct: 829  GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFP 888

Query: 1512 GAPGVDSSI--------------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRR 1557
            G PG +                  GPTG +GERG +G  G PGP G  G        G R
Sbjct: 889  GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGER 948

Query: 1558 GHTGPQGTAGIPGP---------DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP 1608
            G  GPQG  G PGP         DGL G  G +G  G +G+ G  G  G VG +GP G  
Sbjct: 949  GPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008

Query: 1609 GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----GSVGRKGAK 1664
            GP GE G+ G  G  G +G PG  G++G  G PGP GL G DG PG     G  G  G  
Sbjct: 1009 GPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPV 1068

Query: 1665 GQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAK 1724
            G  G  G  GP G  G  G PGE G  GA G +   G+PG  G  G PGP G KG  G K
Sbjct: 1069 GALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI---GIPGRPGPQGPPGPAGEKGAPGEK 1125

Query: 1725 G 1725
            G
Sbjct: 1126 G 1126



 Score =  266 bits (679), Expect = 2e-70
 Identities = 153/334 (45%), Positives = 172/334 (51%), Gaps = 12/334 (3%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGY------LGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G MG PGPPG RGP G  G++G       +G  G  GE+G PG  GE G  G  G  
Sbjct: 1243 GDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPP 1302

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GPKG RG  G+ G  G  G  G  G  GD+G  G  G  G  G  G PG+ G  G  G  
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP 1362

Query: 1506 GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G +GD G PG   S  GPTG  G  G  G+RG PGP G  G + +  A G  G  GP G 
Sbjct: 1363 GDKGDDGEPGQTGS-PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK 1421

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G  GP G  G     GP G RG  G  GE+G  GS GP GPPGP G  G  G  G  G 
Sbjct: 1422 TGPIGPQGAPGK---PGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP 1478

Query: 1626 KGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGP 1685
            KGE G  G  G +G PG +G +G+ G PG    G  G KG++G  G SGP G  G PG P
Sbjct: 1479 KGEKGHPGLIGLIGPPGEQGEKGDRGLPG--PQGSSGPKGEQGITGPSGPIGPPGPPGLP 1536

Query: 1686 GETGLKGARGKMISAGLPGEMGSPGEPGPPGRKG 1719
            G  G KGA+G     G  GE G PG PGPPG  G
Sbjct: 1537 GPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  263 bits (673), Expect = 1e-69
 Identities = 150/335 (44%), Positives = 171/335 (51%), Gaps = 9/335 (2%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ G  G+ G PG KGS+G  GE+G  G  G  GP+G+ G  G  G  GP+G +
Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL GQ+G+ G  G  G  G  G  GLPG  GEKG+ G  G  G  G PG RG  G  G  
Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G  G    I  P G  GE+G  G  G PG PG  G        G +G +GP G AG PGP
Sbjct: 1267 GPQGPPGGIGNP-GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP 1325

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G  G  G KG  GP G  G  G  G  G  G  GPPG  G+ G  G+ GS G  GEPG 
Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP 1385

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLK 1691
             G  G  G PGP G +G  G  G      KG  G EG PG++GP G  G PG PG  GL+
Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKG-----AKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 1692 GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            G  G +   GLPG   SPG  GPPG  G  G  GL
Sbjct: 1441 GIPGPVGEQGLPG---SPGPDGPPGPMGPPGLPGL 1472



 Score =  260 bits (664), Expect = 1e-68
 Identities = 158/382 (41%), Positives = 183/382 (47%), Gaps = 38/382 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIA---------------GERGAPGPVGE 1435
            +G  G  G PGPPG++G PG  G EG  G+ G A               G+RG PGPVG 
Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEK---GDEGSQGS 1492
             G KG  G  GP G  G  G+ G  G  G  G+ G  G  G PG  GEK   G++G QG 
Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGP 1130

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIE--GPTGLKGERGRQGRRGWPGPPGTPGSRRK 1550
             G+ G  G  G  G  G  G PG D      G  G KG +G +G +G PGP G  G   +
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 1551 TAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGP---RGEAGVKGEKGGVGSKGPQGP 1607
                G  G  GP+G  G+ G  G EG  G  GP GP   +G  G  GEKG  G  G  GP
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250

Query: 1608 PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQE 1667
            PGP G  G  G  G+ G +G PG +G  GAVG  G  G  G  G PG G  G  G KG+ 
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG--GPPGPKGER 1308

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            G  GESGP G  G PG  G  G  G +G     G PG+ G PGEPGP G+ G  G KG  
Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG-- 1366

Query: 1728 SFSTCELIQYVRDRSPGRHGKP 1749
                        D  PG+ G P
Sbjct: 1367 -----------DDGEPGQTGSP 1377



 Score =  257 bits (656), Expect = 1e-67
 Identities = 161/410 (39%), Positives = 199/410 (48%), Gaps = 76/410 (18%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGI-------------AGERG--------- 1428
            +G  G +GDPG  G  G PG  G++G  G  G              AG +G         
Sbjct: 486  MGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQ 545

Query: 1429 -----------APGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL 1477
                         GP G  G  G  G  GP G+ GL G+ G+VG  G  G+ G  G  G 
Sbjct: 546  AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGK 605

Query: 1478 PGRKGEKGDEGSQGSPGKRGTPGDR---------GAKGLRGDPGAPGV-----------D 1517
            PGR+G  G +G++G PG+ G  GDR         G KG RGDPG  G            D
Sbjct: 606  PGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGD 665

Query: 1518 SSIEGPTGLKGE---RGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGL 1574
                GP GL GE   RG  G +G PGPPG PG        G +G+ GPQG    PGP G 
Sbjct: 666  DGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGE---PGPPGQ 722

Query: 1575 EGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE 1634
            +G+ G +G  GP+G  G  GEKG +G  G  G PG  G  G+ G+ G  G KG  G  G 
Sbjct: 723  QGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGP 782

Query: 1635 KGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFP------GESGPKGEIGDPGGPGET 1688
            +G +G+PGPRG++G DG  G    G KG KG++GFP      G  G +GEIG PG  GE 
Sbjct: 783  QGPIGYPGPRGVKGADGIRGL--KGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGED 840

Query: 1689 GLKGARGKMISAGLPGEMGSPGE---------PGPPGRKGVKGAKGLASF 1729
            G +G +G+    G PG +G PGE         PG PGR+G KG+ G   F
Sbjct: 841  GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890



 Score =  256 bits (653), Expect = 2e-67
 Identities = 153/371 (41%), Positives = 180/371 (48%), Gaps = 41/371 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE---------QGTKGCY 1442
            G  G  G PGP G  G  G KG  G +G +G  G +G PGP G+          G +G  
Sbjct: 562  GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMP 621

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  GPKG+RG +G  G  GE G  G  G  G  G PG  GE+GD+G  G  G  G PG R
Sbjct: 622  GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G  G +G PG PG    + G  G  G +G  G +G PGPPG  G+       G +G  GP
Sbjct: 682  GLLGPKGPPGPPG-PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGP---PGPGGEAGNQGR 1619
             G  G  G  GL G  G  GP G  G+ G  GEKGG G  GPQGP   PGP G  G  G 
Sbjct: 741  PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGI 800

Query: 1620 LGSQGNKGEPGD------------LGEKGAVGFPGPRGLQGNDGSPGY------------ 1655
             G +G KGE G+             G++G +G PGPRG  G +G  G             
Sbjct: 801  RGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP 860

Query: 1656 -GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G  G+ G  G  G+PG  GPKG IG PG PG  G KG RG   + G PG  G  G  GP
Sbjct: 861  PGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG---TPGKPGPRGQRGPTGP 917

Query: 1715 PGRKGVKGAKG 1725
             G +G +G  G
Sbjct: 918  RGERGPRGITG 928



 Score =  249 bits (636), Expect = 2e-65
 Identities = 160/401 (39%), Positives = 192/401 (47%), Gaps = 46/401 (11%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGP---------VGEQGTKGC 1441
            +G  G  G  GPPG  G PG +G  G  G  G+ G+ G  G           GE+G +G 
Sbjct: 588  VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647

Query: 1442 YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGD 1501
             G  GP G  G +G+ G+ GE G  GL GE G  GL G KG  G  G  G  G  G PG 
Sbjct: 648  PGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707

Query: 1502 RGAKGLRGDPGAPGVDSS-----------IEGPTGLKGERGRQGRRGWP---GPPGTPGS 1547
            +G  G +G+PG PG   +             GP G KG  G+ G  G P   GPPG PG 
Sbjct: 708  KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767

Query: 1548 RRKTAAHGRRGHTGPQGTAGIPGPDGLEGS---LGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
                   G +G  GPQG  G PGP G++G+    GLKG +G +GE G  G KG +G KG 
Sbjct: 768  EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827

Query: 1605 Q---GPPGPGGEAGNQGRLGSQGNKGEPGDL---GEKGAVGFPGPRGLQGNDGSPGY--- 1655
            +   GPPGP GE G +G  G  G  G+PG L   GEKG +G PG  G  G  G  G    
Sbjct: 828  RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887

Query: 1656 -GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G  G  G KG  G PG+ GP+G+ G  G  GE G +G  GK    G  G  G  G  GP
Sbjct: 888  PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK---PGPKGNSGGDGPAGP 944

Query: 1715 PGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
            PG +G  G +G   F   +         PG  GK   P HP
Sbjct: 945  PGERGPNGPQGPTGFPGPK-------GPPGPPGKDGLPGHP 978



 Score =  248 bits (633), Expect = 5e-65
 Identities = 147/351 (41%), Positives = 173/351 (49%), Gaps = 17/351 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  GDPGP G  GPPG  G  G  GE G  G  G PGP G  G KG  G  GP G  
Sbjct: 640  GEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT 699

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G++GQ G  G  G  G  G  G  G PG +G  G +G+ G PG++G  G  G  G+ G  
Sbjct: 700  GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD 759

Query: 1512 GAPGVDSSIEGPTGLKGERGR---QGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G PG     EGP G KG +G    QG  G+PGP G  G+       G +G  G  G  G 
Sbjct: 760  GPPGHPGK-EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGF 818

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
             G  G++G  G  GP GPRGE G +G KG     GP G PGP G  G +G+LG  G  G 
Sbjct: 819  KGDMGIKGDRGEIGPPGPRGEDGPEGPKG---RGGPNGDPGPLGPPGEKGKLGVPGLPGY 875

Query: 1629 PGDLGEKGAVGFPG------PRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGE 1678
            PG  G KG++GFPG       +G +G  G PG     G  G +G +G  G  G+ GPKG 
Sbjct: 876  PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGN 935

Query: 1679 IGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
             G  G  G  G +G  G     G PG  G PG PG  G  G  G +G   F
Sbjct: 936  SGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986



 Score =  222 bits (565), Expect = 4e-57
 Identities = 134/306 (43%), Positives = 160/306 (52%), Gaps = 30/306 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG PG+ GPPG KG  G  GE G +G  G PGP G  G  G  G+ GP G  
Sbjct: 1285 GEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFP 1344

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG---DEGSQGSPGKRGTPGDRGAKGLR 1508
            G  G  GE G  G DG  G++GD+G PG+ G  G   + G  G PGKRG PG  G +G +
Sbjct: 1345 GDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQ 1404

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G+ GA G ++ +EGP G  G  G QG  G PGP G           G  G  G QG  G 
Sbjct: 1405 GEKGAKG-EAGLEGPPGKTGPIGPQGAPGKPGPDGL---------RGIPGPVGEQGLPGS 1454

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN--- 1625
            PGPDG  G +G  G  G +G++G KGEKG  G  G  GPPG  GE G++G  G QG+   
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514

Query: 1626 KGEPGDLGEKGAVGFPGPRGL---------QGNDGSPGYGSVGRKGAKGQEGFPGESGPK 1676
            KGE G  G  G +G PGP GL         +G+      G  G KG  G  G PG  GP 
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSS-----GPTGPKGEAGHPGPPGPPGPP 1569

Query: 1677 GEIGDP 1682
            GE+  P
Sbjct: 1570 GEVIQP 1575



 Score =  202 bits (514), Expect = 3e-51
 Identities = 133/335 (39%), Positives = 158/335 (47%), Gaps = 55/335 (16%)

Query: 1443 GTKGPKGNRGLNGQEGEVGENG--IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPG 1500
            G  GP+G +G  G+   + E G  I+G  G +G  GLPG  G  G  G  G PG+RG PG
Sbjct: 444  GIGGPRGEKGQKGEPAII-EPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPG 502

Query: 1501 DRGAKGLRGDPGAPGV------------DSSIEGP-----------------TGLKGERG 1531
              G  G  G PG PG             D+  +GP                   L+G  G
Sbjct: 503  RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562

Query: 1532 RQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP------------DGLEGSLG 1579
              G  G PGP G PGS       G  G  GP+G  G PGP            DG  G  G
Sbjct: 563  PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622

Query: 1580 LKGPQGPR---GEAGVKGEKGGVGSKGPQGPPGP---GGEAGNQGRLGSQGNKGEPGD-- 1631
              GP+G R   G AG+ GEKG  G  GP GPPGP    GE G+ G +G +G  GEPG   
Sbjct: 623  QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682

Query: 1632 -LGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL 1690
             LG KG  G PGP G+ G DG P  G  G  G +G+ G PG+ G  G  G PG  G  G 
Sbjct: 683  LLGPKGPPGPPGPPGVTGMDGQP--GPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G +G +   GLPG  G+ G PG PG++G  G KG
Sbjct: 741  PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775



 Score =  179 bits (453), Expect = 4e-44
 Identities = 103/241 (42%), Positives = 126/241 (52%), Gaps = 13/241 (5%)

Query: 1391 IGGDGTMGDPGPP---GKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP 1447
            +G  G  G PG P   G+ GPPG KG +G  G+ G  G  G PGP G  G +G  G  GP
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
            +G +G  G +GE G  G  G  G  G  G PG+ G  G  G  G  G++G PG  G  G 
Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAG 1567
             G  G PG+   ++G +G KGE+G  G  G  GPPG  G +      G RG  GPQG++ 
Sbjct: 1461 PGPMGPPGL-PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK------GDRGLPGPQGSS- 1512

Query: 1568 IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKG 1627
              GP G +G  G  GP GP G  G+ G  G  G+KG  GP GP GEAG+ G  G  G  G
Sbjct: 1513 --GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570

Query: 1628 E 1628
            E
Sbjct: 1571 E 1571



 Score =  138 bits (347), Expect = 7e-32
 Identities = 87/201 (43%), Positives = 96/201 (47%), Gaps = 22/201 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPGKRGPPG  G EG  GE+G  GE G  GP G+ G  G  G  G  G  
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437

Query: 1452 GLNGQEGEVGENGI------DGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GL G  G VGE G+      DG  G  G  GLPG KG+ G +G +G PG  G  G  G +
Sbjct: 1438 GLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497

Query: 1506 GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPG---------SRRKTAAHGR 1556
            G +GD G PG   S  GP G +G  G  G  G PGPPG PG         S   T   G 
Sbjct: 1498 GEKGDRGLPGPQGS-SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556

Query: 1557 RGHT------GPQGTAGIPGP 1571
             GH       GP G    P P
Sbjct: 1557 AGHPGPPGPPGPPGEVIQPLP 1577



 Score =  115 bits (289), Expect = 4e-25
 Identities = 81/223 (36%), Positives = 106/223 (47%), Gaps = 23/223 (10%)

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
            PG P    +I    G+ G RG +G++G P     PG   +       G  GP+G AG+PG
Sbjct: 432  PGMPANQDTIY--EGIGGPRGEKGQKGEPAII-EPGMLIE-------GPPGPEGPAGLPG 481

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP-------GPGGEAGNQGRLGSQ 1623
            P G  G  G  G  G RG  G  G  G  G  GP G         G GG+AG++G + S 
Sbjct: 482  PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS- 540

Query: 1624 GNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPG 1683
              + +   + ++  +   GP G  G  G PG   VG  G+ G +G PG+ GP+G  G  G
Sbjct: 541  AQESQAQAILQQARLALRGPAGPMGLTGRPG--PVGPPGSGGLKGEPGDVGPQGPRGVQG 598

Query: 1684 GPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
             PG  G  G RG+   AG  G  G PG+ GP G +G  G  GL
Sbjct: 599  PPGPAGKPGRRGR---AGSDGARGMPGQTGPKGDRGFDGLAGL 638



 Score = 61.6 bits (148), Expect = 8e-09
 Identities = 52/158 (32%), Positives = 59/158 (37%), Gaps = 32/158 (20%)

Query: 1598 GVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGP------RGLQGNDG 1651
            G G + P  P  PG  A          N   P     +GA    G       R L  N  
Sbjct: 358  GEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYY 417

Query: 1652 SPGY----------------------GSVGRKGAKGQEGFPGESGPKGEI-GDPGGPGET 1688
             P Y                      G  G +G KGQ+G P    P   I G PG  G  
Sbjct: 418  DPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPA 477

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            GL G  G M   G  G++G PGE GPPGR G+ GA GL
Sbjct: 478  GLPGPPGTM---GPTGQVGDPGERGPPGRPGLPGADGL 512



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 34/91 (37%), Positives = 37/91 (40%), Gaps = 10/91 (10%)

Query: 1639 GFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMI 1698
            G  GPRG +G  G P     G       EG PG  GP G  G PG  G TG  G  G+  
Sbjct: 444  GIGGPRGEKGQKGEPAIIEPGML----IEGPPGPEGPAGLPGPPGTMGPTGQVGDPGER- 498

Query: 1699 SAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
                 G  G PG PG  G  G  G   +  F
Sbjct: 499  -----GPPGRPGLPGADGLPGPPGTMLMLPF 524


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  275 bits (703), Expect = 4e-73
 Identities = 161/374 (43%), Positives = 197/374 (52%), Gaps = 39/374 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ G PG  G PGF+G +G  G  G  G RG PGP+G+ G KG  G  GP G  
Sbjct: 850  GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPE 909

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS------------QGSPGKRGTP 1499
            G  G  G  G+NG +G+ G+ G  GLPG +G+ G EG             +G PG++G P
Sbjct: 910  GFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFP 969

Query: 1500 GDRGAKGLRGDPGAPGVDSSI--------------EGPTGLKGERGRQGRRGWPGPPGTP 1545
            G  G  G++G+PG PG    +               G  G KG+RG  G  G PGP G+ 
Sbjct: 970  GRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSM 1029

Query: 1546 GSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQ 1605
            G        G  G  GPQG  G  GP G+ G+ G +GP+GP G AG +G +G  G  GPQ
Sbjct: 1030 GHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQ 1089

Query: 1606 GPPG-PG--GEAGNQGRLGSQGNKGEPGDL---GEKGAVGFPGPRGLQGNDGSPG-YGSV 1658
            G PG PG  G AG +G LGS+G  G PG     G KG  G PGP+G QG  G PG  G  
Sbjct: 1090 GRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPK 1149

Query: 1659 GRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEM------GSPGEP 1712
            G  GA G+ G PGE+G KG++G  G PGE GL G RG+    G  G M      G  G+P
Sbjct: 1150 GPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209

Query: 1713 GPPGRKGVKGAKGL 1726
            GP G  G KG +GL
Sbjct: 1210 GPDGEHGEKGQEGL 1223



 Score =  265 bits (677), Expect = 4e-70
 Identities = 156/381 (40%), Positives = 192/381 (50%), Gaps = 54/381 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G MG PG PG +GPPG +G  G  G +G  G RG  GP GEQG++G  G  GP+G  
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 1452 GLNGQEGEVGENG---------IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG----- 1497
            G  GQ+G  GE G         I G +G  G  GLPG  G +G +G  G PG+ G     
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPP 1152

Query: 1498 ----------------------TPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGR 1535
                                  TPG++G  G RG+PG  G DS   GP GLKG+RG    
Sbjct: 1153 GAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEG-DSGPMGPDGLKGDRGD--- 1208

Query: 1536 RGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE 1595
               PGP G  G + +    G  G  GP G  G+ GP+G  G  G KG  G +G  G +G+
Sbjct: 1209 ---PGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQ 1265

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG- 1654
             G +G  G  GPPG  G  G++G LG  G  G  G  GE G  G+ G +G+ G  G PG 
Sbjct: 1266 LGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGP 1325

Query: 1655 YGSVGRKG----AKGQEGFPGESGP------KGEIGDPGGPGETGLKGARGKMISAGLPG 1704
             G  G +G    A+G  G PG+ GP      +GE GDPG PG+ G++G RGK    G PG
Sbjct: 1326 KGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPG 1385

Query: 1705 EMGSPGEPGPPGRKGVKGAKG 1725
              G  G PGP G KG +G KG
Sbjct: 1386 HPGPRGWPGPKGSKGAEGPKG 1406



 Score =  261 bits (666), Expect = 7e-69
 Identities = 159/372 (42%), Positives = 193/372 (51%), Gaps = 37/372 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPG------------FKGSEGYLGEEGIAGERGAPGPVGEQGT 1438
            +G DG  G PG  G RGP G             KG++GY G+ G  G  G PGP G  G 
Sbjct: 1224 MGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGP 1283

Query: 1439 KGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGS------ 1492
            KG  G+ GP G  G  G +GE G  G DG  G  G  G PG KGEKG++G  G       
Sbjct: 1284 KGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPG 1343

Query: 1493 -PGKRGTPGDRGAKGLRGDPGAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGS-- 1547
             PG RG  GDRG +G  GDPG PG +    + G  G +G+ G  G RGWPGP G+ G+  
Sbjct: 1344 PPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEG 1403

Query: 1548 -RRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRG------EAGVKGEKGGVG 1600
             + K    G  G  G QG  G+PGP G+ G  GL+G  GP G      +AG +GE+G  G
Sbjct: 1404 PKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDG 1463

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----G 1656
              GP GP G  G  G  G  G+QG  G  G+ G  G +G PG RG +G  G PG     G
Sbjct: 1464 DPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPG 1523

Query: 1657 SVGRKGAKGQEGFPGES---GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPG 1713
            S G+ G  G+ GFPG +   GPKG  GD G  G  G +G  G M   G+ G +G  G  G
Sbjct: 1524 SKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSG 1583

Query: 1714 PPGRKGVKGAKG 1725
             PG KG KG++G
Sbjct: 1584 LPGPKGDKGSRG 1595



 Score =  258 bits (658), Expect = 6e-68
 Identities = 158/374 (42%), Positives = 191/374 (51%), Gaps = 53/374 (14%)

Query: 1392 GGDGTMGDPGPPGKRGP---PGFKGSEGYLGEEGIAGERG---------APGPVGEQG-- 1437
            G DG  G+PG PG+ GP    GF G  G +GE GI GE+G          PGP G  G  
Sbjct: 973  GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032

Query: 1438 -------TKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDE 1487
                   T G  G +GP G+RG   + G +G  G  G DG  GEQG  GL   KG  G +
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL---KGPPGPQ 1089

Query: 1488 GSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGS 1547
            G  G PG++G  G+RG  G RG PG PG      GP G KG  G  G +G  GP G PG 
Sbjct: 1090 GRPGRPGQQGVAGERGHLGSRGFPGIPGP----SGPPGTKGLPGEPGPQGPQGPIGPPGE 1145

Query: 1548 RRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGP 1607
                   G +G  G  G  G+PG  G++G LG  G  G +G  G +GE G  G  GP GP
Sbjct: 1146 M------GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 1608 PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQ 1666
             G  G+ G+ G  G  G KG+ G +GE G  G PG  G++G +G  G  G  GR GAKG 
Sbjct: 1200 DGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGA 1259

Query: 1667 EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEP-------------- 1712
            +G+ G+ G  G  GDPG PG  G KG+RG +   G PG MG+ GEP              
Sbjct: 1260 KGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGP 1319

Query: 1713 -GPPGRKGVKGAKG 1725
             GPPG KG KG +G
Sbjct: 1320 LGPPGPKGEKGEQG 1333



 Score =  258 bits (658), Expect = 6e-68
 Identities = 160/396 (40%), Positives = 203/396 (51%), Gaps = 36/396 (9%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGA---PGPVGEQGTKGCYG 1443
            F   +G  G +G+ G  G  GPPG  G +G +G  G+ G  G    PGP G  G++G  G
Sbjct: 998  FIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057

Query: 1444 TKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGR------KGEKGDEGSQGSPGKRG 1497
             +G KG RG  G +G  GE G  GL G  G  G PGR       GE+G  GS+G PG  G
Sbjct: 1058 MRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117

Query: 1498 TPGDRGAKGLRGDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPGPPGTPGSRR 1549
              G  G KGL G+PG  G    I        +GP G  GE G  G  G  G  G  G+  
Sbjct: 1118 PSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPG 1177

Query: 1550 KTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP- 1608
            +    G+RG  G +G +G  GPDGL+G    +G  GP GE G KG++G +G  GP GPP 
Sbjct: 1178 EQGLIGQRGEPGLEGDSGPMGPDGLKGD---RGDPGPDGEHGEKGQEGLMGEDGPPGPPG 1234

Query: 1609 -----GPGGEAGNQ---GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----YG 1656
                 GP G++G Q   GR G++G KG  G LGE G  G PGP G  G  GS G     G
Sbjct: 1235 VTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTG 1294

Query: 1657 SVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPG 1716
            + GR GA+G+ G  G  G KG +G  G PG  G KG +G+       G  G PG+ GP G
Sbjct: 1295 APGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE--DGKAEGPPGPPGDRGPVG 1352

Query: 1717 RKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECP 1752
             +G +G  G   +   E +Q +R + PG+ G+P  P
Sbjct: 1353 DRGDRGEPGDPGYPGQEGVQGLRGK-PGQQGQPGHP 1387



 Score =  256 bits (653), Expect = 2e-67
 Identities = 157/377 (41%), Positives = 191/377 (50%), Gaps = 48/377 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGC---------Y 1442
            G  G MG PG  G  GPPG KG +GY G  G  GE+G PGP G  G KG           
Sbjct: 688  GAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV 747

Query: 1443 GTKGPKGNR---------GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSP 1493
            G  GPKG+R         GL G +GE G  G+ G  G+ G  G PG  GE+G  G  G+P
Sbjct: 748  GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807

Query: 1494 GKRGT---------------------PGDRGAKGLRGDPGAPGV--DSSIEGPTGLKGER 1530
            G+ G                      PG +G KGL G  G PG+  D   +G  G+ G+ 
Sbjct: 808  GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDP 867

Query: 1531 GRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEA 1590
            G QG +G  G PG PG+R K    G  G  G +G+ G PGP G EG  G  GP G  G  
Sbjct: 868  GFQGDKGSQGLPGFPGARGKP---GPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPE 924

Query: 1591 GVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
            G+KG+ G  G  GP+G  GP G+ G  G  G+ G +G+P   G KG  G PG  G++G  
Sbjct: 925  GMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQP---GRKGFPGRPGLDGVKGEP 981

Query: 1651 GSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSP 1709
            G PG  G VG +G  G  G  GE G  GE GD G  G  G+ G +G M   G+PG MG+P
Sbjct: 982  GDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTP 1041

Query: 1710 GEPGPPGRKGVKGAKGL 1726
            GEPGP G  G +G  G+
Sbjct: 1042 GEPGPQGPPGSRGPPGM 1058



 Score =  255 bits (651), Expect = 4e-67
 Identities = 146/350 (41%), Positives = 174/350 (49%), Gaps = 19/350 (5%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G DG  GD G PG  G  G KG EG +GE+G  G  G  G  G +G  G  G KG  G 
Sbjct: 1197 MGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256

Query: 1451 RGLNGQEGEVGENGIDG------------LNGEQGDNGLPGRKGEKGDEGSQGSPGKRGT 1498
            +G  G +G++GE G+ G              G  G  G PGR G +G+ G  G  G +G 
Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316

Query: 1499 PGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG 1558
             G  G  G +G+ G  G D   EGP G  G+RG  G RG  G PG PG   +    G RG
Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376

Query: 1559 HTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
              G QG  G PGP G  G  G KG +GP+G+ G  G  G  G +G QG PGP G  G QG
Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              G  G  G PG  G+       G +G QG+DG PG  G  G++G  G  G PG  GP G
Sbjct: 1437 LEGIAGPDGLPGRDGQ------AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPG 1490

Query: 1678 EIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
              G+ G PG+ G  G RG     GLPG  G PG  G PG  G  G  G+A
Sbjct: 1491 FKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMA 1540



 Score =  253 bits (645), Expect = 2e-66
 Identities = 150/373 (40%), Positives = 189/373 (50%), Gaps = 40/373 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG---------- 1440
            +G  GT G+ G  G+RG PG +G  G +G +G+ G+RG PGP GE G KG          
Sbjct: 1170 LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGP 1229

Query: 1441 -----CYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK 1495
                   G +GP+G  G  G++G  G  G  G  G+ G+ G+PG  G  G  G +GS G 
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 1496 RGTPGDRGAKGLRGDPGAPGVDSSIE-----GPTGLKGERGRQGRRGWP-GPPGTPGSRR 1549
             G  G  G  G +G+PG  G D         GP G KGE+G QG  G   GPPG PG R 
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349

Query: 1550 KTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPG 1609
                 G RG  G  G  G PG +G++G  G  G QG  G  G +G  G  GSKG +GP G
Sbjct: 1350 PV---GDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKG 1406

Query: 1610 PGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEG 1668
              G+AG  GR G QG +G PG    +G VG  G  G+ G DG PG  G  G++G +G +G
Sbjct: 1407 KQGKAGAPGRRGVQGLQGLPGP---RGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDG 1463

Query: 1669 FPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE------------PGPPG 1716
             PG  GP G+ G+PG  G  G +G  G    +GLPG++G PG+             G PG
Sbjct: 1464 DPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPG 1523

Query: 1717 RKGVKGAKGLASF 1729
             KG  G  G   F
Sbjct: 1524 SKGQPGDSGEMGF 1536



 Score =  249 bits (636), Expect = 2e-65
 Identities = 151/375 (40%), Positives = 185/375 (49%), Gaps = 42/375 (11%)

Query: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
            MG PGP G  G PG  G  G  G  G  G RG PGP G  G  G  G KG KG+ GL+  
Sbjct: 624  MGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPG 683

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
            +   G  G  GL G  G+ G PGRKG KG  G  G PG++G PG  G+ G +G PG  G+
Sbjct: 684  KAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGL 743

Query: 1517 DSSI-----------------------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAA 1553
               +                       +G  GL G  G++G+ G PG PG  G R     
Sbjct: 744  PGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGL 803

Query: 1554 HGRRGHTGPQGTAGIP---------GPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
             G  G  G  G  G+P         GP G  G  G+KG  G  GE G+KG+KG  G  G 
Sbjct: 804  DGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGV 863

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDL---GEKGAVGF---PGPRGLQGNDGSPG---- 1654
             G PG  G+ G+QG  G  G +G+PG L   G+KG++GF   PGP G  G+ G PG    
Sbjct: 864  SGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGP 923

Query: 1655 YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G  G+ GA+G  G  G+ GP+G+ G  G PG  GL+G  G+    G PG  G  GEPG 
Sbjct: 924  EGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGD 983

Query: 1715 PGRKGVKGAKGLASF 1729
            PGR G  G +G   F
Sbjct: 984  PGRPGPVGEQGFMGF 998



 Score =  214 bits (545), Expect = 8e-55
 Identities = 135/311 (43%), Positives = 157/311 (50%), Gaps = 16/311 (5%)

Query: 1423 IAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKG 1482
            +AG    P  +G  G KG  G  GP G  GL G  G  G  G  G  G  G  G PG KG
Sbjct: 614  LAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKG 673

Query: 1483 EKGDEGSQGSPGKR--GTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPG 1540
            +KGD G   SPGK   G  GD G  GL G+PG PG     +G  G  G  G  G +G PG
Sbjct: 674  QKGDPGL--SPGKAHDGAKGDMGLPGLSGNPGPPG----RKGHKGYPGPAGHPGEQGQPG 727

Query: 1541 PPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVG 1600
            P G+PG++      G  G  G  G  G  G  GL G  GL G  G RG  GV G++G +G
Sbjct: 728  PEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMG 787

Query: 1601 SK------GPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG 1654
                    G +GPPG  G  G  G  G  G  G  GDLG  G +G+PGP+G++G  GS  
Sbjct: 788  MPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGS-- 845

Query: 1655 YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G  G KG KG++G PG SG  G  GD G  G  G  GARGK    G  G+ GS G PGP
Sbjct: 846  VGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905

Query: 1715 PGRKGVKGAKG 1725
            PG +G  G  G
Sbjct: 906  PGPEGFPGDIG 916



 Score =  210 bits (535), Expect = 1e-53
 Identities = 128/305 (41%), Positives = 155/305 (50%), Gaps = 25/305 (8%)

Query: 1392 GGDGTM-GDPGPPGKRGPPGFKGSEG------YLGEEGIAGERGAPGPVGEQGTKGCYGT 1444
            G DG   G PGPPG RGP G +G  G      Y G+EG+ G RG PG  G+ G  G  G 
Sbjct: 1333 GEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392

Query: 1445 KGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGA 1504
             GPKG++G  G +G+ G+ G  G  G QG  GLPG +G  G +G +G  G  G PG  G 
Sbjct: 1393 PGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQ 1452

Query: 1505 KGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQG 1564
             G +G+ G    D    GP G  G+RG  G  G PG  G PG          +G +G  G
Sbjct: 1453 AGQQGEQG----DDGDPGPMGPAGKRGNPGVAGLPGAQGPPGF---------KGESGLPG 1499

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
              G PG  G EG  GL G QG  G  G  G+ G +G  G  G  GP G  G+ G  G QG
Sbjct: 1500 QLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQG 1559

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             +G PG +G++G V   GP G+ G  G P  G  G KG++G  G  G  GP G  G PG 
Sbjct: 1560 PRGPPGLMGKEGIV---GPLGILGPSGLP--GPKGDKGSRGDWGLQGPRGPPGPRGRPGP 1614

Query: 1685 PGETG 1689
            PG  G
Sbjct: 1615 PGPPG 1619



 Score =  154 bits (388), Expect = 1e-36
 Identities = 108/279 (38%), Positives = 123/279 (44%), Gaps = 68/279 (24%)

Query: 1526 LKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSL------- 1578
            L G  G +G  G PGPPG PG      A G RG  GP G  G+PGP G +G         
Sbjct: 623  LMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSP 682

Query: 1579 --------------GLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ---GRLG 1621
                          GL G  GP G  G KG  G  G  G QG PGP G  G +   GR G
Sbjct: 683  GKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQG 742

Query: 1622 SQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFP---GESGP-- 1675
              G  G+PG  G +G +G PG  GL G+DG  G  G  G++G  G  GFP   GE GP  
Sbjct: 743  LPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802

Query: 1676 ----KGEIGDPGGPGETGL---------------KGARGKMISAGLP------GEMGSPG 1710
                 GE+G PG PG  GL               KG +G M S G P      GE G PG
Sbjct: 803  LDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPG 862

Query: 1711 EPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKP 1749
              G PG +G KG++GL  F             PG  GKP
Sbjct: 863  VSGDPGFQGDKGSQGLPGF-------------PGARGKP 888



 Score =  119 bits (298), Expect = 3e-26
 Identities = 71/161 (44%), Positives = 86/161 (53%), Gaps = 14/161 (8%)

Query: 1391 IGGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP 1447
            +G  G  G+PG    PG +GPPGFK      GE G+ G+ G P   G++GT+G  G  G 
Sbjct: 1468 MGPAGKRGNPGVAGLPGAQGPPGFK------GESGLPGQLGPP---GKRGTEGRTGLPGN 1518

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
            +G  G  GQ G+ GE G  G+ G  G  G PG  G KG +G +G PG  G  G  G  G+
Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578

Query: 1508 RGDPGAPGV--DSSIEGPTGLKGERGRQGRRGWPGPPGTPG 1546
             G  G PG   D    G  GL+G RG  G RG PGPPG PG
Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 59/132 (44%), Positives = 68/132 (51%), Gaps = 12/132 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPGKRG  G  G  G  GE G  G+ G  G +G  G  G +G KGP G+ 
Sbjct: 1493 GESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDI 1552

Query: 1452 GLNGQEGE------VGENGIDGLNGEQGDNGLPGRKGEKG---DEGSQGSPGKRGTPGDR 1502
            G  G +G       +G+ GI G  G  G +GLPG KG+KG   D G Q   G RG PG R
Sbjct: 1553 GFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQ---GPRGPPGPR 1609

Query: 1503 GAKGLRGDPGAP 1514
            G  G  G PG P
Sbjct: 1610 GRPGPPGPPGGP 1621



 Score = 68.2 bits (165), Expect = 9e-11
 Identities = 57/199 (28%), Positives = 72/199 (36%), Gaps = 20/199 (10%)

Query: 1541 PPGTPGSRRKTAAHGRR-----GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE 1595
            P  TPGS R T           G + P+    +P P           P G +   G +  
Sbjct: 491  PAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGS--------APTGSKKPIGSEAS 542

Query: 1596 KGGVGSKGPQGP----PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDG 1651
            K       P+ P    PG          L ++ +  +P    +        P     +  
Sbjct: 543  KKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602

Query: 1652 SPGYGSVGRKGAKGQEGFP---GESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGS 1708
             P           G   FP   G  GPKG+ G PG PG  GL G  G     G PG  G+
Sbjct: 603  RPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662

Query: 1709 PGEPGPPGRKGVKGAKGLA 1727
            PG PGPPG KG KG  GL+
Sbjct: 663  PGLPGPPGAKGQKGDPGLS 681


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  270 bits (690), Expect = 1e-71
 Identities = 152/358 (42%), Positives = 183/358 (51%), Gaps = 24/358 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPG +GP G+ G  G  G +G+ G +G+ G  GE G  G  G  G KG+R
Sbjct: 751  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 810

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  GQ G  GE+G +G  G  G  G PG  G+ G++G  G PG  G PG +G KG  G P
Sbjct: 811  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870

Query: 1512 GAPGVDSSI--------------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRR 1557
            G PG +                  GPTG +G RG +G  G PGP GT G        G R
Sbjct: 871  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930

Query: 1558 GHTGPQGTAGIPGP---------DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP 1608
            G  GPQG  G PGP         DGL G  G +G  G +G+ G  G  G VG +GP G  
Sbjct: 931  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 990

Query: 1609 GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQE 1667
            GP GE G+ G  G  G +G PG  G++GA G PGP+G+ G DG  G  G  G +G  G +
Sbjct: 991  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1050

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G PG  G +G  G PG  G  G +G+ G     GLPG  G  G PGP G KG  G KG
Sbjct: 1051 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108



 Score =  265 bits (677), Expect = 4e-70
 Identities = 156/346 (45%), Positives = 179/346 (51%), Gaps = 17/346 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GG+G  G PGP G  G  G  G+ G +G  G  G +G PGP GE+G  G  G +GP G  
Sbjct: 1057 GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1116

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G+ G  G  G  G  G  GE GD G    PG+KG KGD+G  G PG  G  G  GA G+ 
Sbjct: 1117 GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1176

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH---TGPQGT 1565
            G  G PG      G  G+ G++G +G RG+PGPPG  G +      G +G     GP G 
Sbjct: 1177 GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G PGP G +G  G  GPQGP G  G  G  G  G  G  G PGP GEAG  G  G +G 
Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1292

Query: 1626 KGE---PGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGD 1681
            KGE   PG  G  GA G PG  G +GN G  G+ G  G  G  G  G  G  G KGE GD
Sbjct: 1293 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1352

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            PG PG  G  G  G     G PG+ G PG  G  GR+G KGAKG A
Sbjct: 1353 PGQPGPPGPSGEAG---PPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395



 Score =  261 bits (667), Expect = 6e-69
 Identities = 153/349 (43%), Positives = 183/349 (52%), Gaps = 21/349 (6%)

Query: 1395 GTMGDPGPPGKRGP------PGFKGSEGYLGEEGIAGE---RGAPGPVGEQGTKGCYGTK 1445
            G  G PG PG++GP      PGF G+ G  G  G+AG+   RG  GP G +G++G  G  
Sbjct: 850  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 909

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  G +G +G +G  G  G  G  G QG  G PG KG  G  G  G PG  G  G+ G +
Sbjct: 910  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969

Query: 1506 GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G  G PG  GV    +GPTG  G  G +G  G PGPPG  G        G +G  GPQG 
Sbjct: 970  GKTGPPGPGGVVGP-QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
            +G  GP GL G  G +G  G +G  G+KG +G  G  GP G PG  G AG  G +G  G 
Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1088

Query: 1626 ---KGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
               +G PG  GEKGA G  GP+G  G DG    G VG  G  G  G PGE G KGEIG+P
Sbjct: 1089 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--QGPVGLPGPAGPAGSPGEDGDKGEIGEP 1146

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSP------GEPGPPGRKGVKGAKG 1725
            G  G  G KG  G     GL G +G+P      GEPGP G++G+ G KG
Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1195



 Score =  261 bits (667), Expect = 6e-69
 Identities = 160/390 (41%), Positives = 194/390 (49%), Gaps = 54/390 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGS---------------------EGYLGEEGIAGERGA 1429
            +G  G  G PGPPGK G PG  G                      +G  GE G  GERG 
Sbjct: 939  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 998

Query: 1430 PGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE---KGD 1486
            PGP G  G +G  G  G +G +G  G +G  G++G  GL G  G+ GLPG +G    KG 
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 1487 EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP----- 1541
            EG QG PG  G+PG+RG+ G  G  G PG     +GP G  GE+G  G +G  GP     
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKGPQGPAGRDG 1117

Query: 1542 ----------------PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG 1585
                            PG  G + +    G++G  G +G  G PGP GL+G +G  G  G
Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177

Query: 1586 PRGEAGVKGEKGGVGSKGPQGP---PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPG 1642
              GE G +G++G  G KG +G    PGP G  G QG  G  G KGE GD+G  G  G PG
Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237

Query: 1643 PRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL---KGARGKMIS 1699
            PRG QG +G+   G  G  G+ G  G  GE G  GE G+PG PGE G+   KG RG+   
Sbjct: 1238 PRGPQGPNGAD--GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295

Query: 1700 AGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            AG PG  G PG  GPPG  G KG  G   F
Sbjct: 1296 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325



 Score =  257 bits (656), Expect = 1e-67
 Identities = 164/416 (39%), Positives = 199/416 (47%), Gaps = 81/416 (19%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQ----------GTKGC 1441
            G  G MG PG  G  GPPG  G  G  G  G+ G  G PGP G            G+KG 
Sbjct: 460  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 519

Query: 1442 -----------------YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEK 1484
                                +GP G  GL G+ G VG  G  G  GE GD G  G +G +
Sbjct: 520  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 579

Query: 1485 GDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGT 1544
            G  G  G PGKRG PG  G +G+ G+PGA G D   +G  GL G++G +G RG  GPPG 
Sbjct: 580  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKG-DRGFDGLPGLPGDKGHRGERGPQGPPGP 638

Query: 1545 PGS------------RRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGE 1589
            PG             R      G RG  GP+GT G PG  G+   +G  G KG  GP+GE
Sbjct: 639  PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 698

Query: 1590 AGVKGEKGGVGSKG---PQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGA 1637
             G  G++G  G +G   PQGP GP GE G QG+ G           G+ G+ G  GEKGA
Sbjct: 699  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 758

Query: 1638 ---------VGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFP---------------GES 1673
                     +G+PGPRG++G DG  G    G KG KG++GFP               G+ 
Sbjct: 759  LGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            GP+GE G  G  G  G  G  G    AG  G++G PG PG PGR+G KG+ G   F
Sbjct: 817  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 872



 Score =  256 bits (655), Expect = 1e-67
 Identities = 157/395 (39%), Positives = 191/395 (48%), Gaps = 57/395 (14%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERG---APGPVGEQGTKGCYGTK 1445
            G  G  G PGP   PGKRG PG  G  G  GE G  G+RG    PG  G++G +G  G +
Sbjct: 574  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 633

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GP G  G +G  GE GE G  GL GE G  GL G +G  G  G  G  G  G PG +G  
Sbjct: 634  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 693

Query: 1506 GLRGDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPG------PPGTPGSRRKT 1551
            G +G+PG PG   +         +GP G  GE+G QG+ G  G      PPG PG   ++
Sbjct: 694  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 753

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGS---LGLKGPQGPRGEAGVKGEKGGVGSKG----- 1603
               G  G  GPQG  G PGP G++G+    GLKG +G +GE G  G KG +G KG     
Sbjct: 754  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 813

Query: 1604 -------------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
                               P G PGP G+AG +G+LG  G  G PG  G KG+ GFPG  
Sbjct: 814  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 873

Query: 1645 GLQGNDGSPGY----------GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            G  G  G+ G           G  G +G++G  G  G+ GPKG  G  G PG  G +G +
Sbjct: 874  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 933

Query: 1695 GKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            G     G PG  G PG PG  G  G  G +G   F
Sbjct: 934  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 968



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/363 (42%), Positives = 188/363 (51%), Gaps = 35/363 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  G  G+ GPPG  G +G +G  GIAG  G PGP G+QG    +G KG +G 
Sbjct: 1143 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM---FGQKGDEGA 1199

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNG------LPGRKGEKGDEGSQGSPGKRGTPG---- 1500
            RG  G  G +G  G+ G  GE+G+NG       PG  G +G +G  G+ G +G PG    
Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259

Query: 1501 -----DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG 1555
                 ++G  G  G+PG PG ++ + GP   KGERG +G  G PG  G PG++      G
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPG-EAGVGGP---KGERGEKGEAGPPGAAGPPGAKGPPGDDG 1315

Query: 1556 RRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAG 1615
             +G+ GP G  G PGP G  G  G  G  G +GE G  G+ G  G  G  GPPGP G+ G
Sbjct: 1316 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1375

Query: 1616 NQGRLGSQGNKGEPGDLGEKGAVGFP---GPRGLQGNDGSPG----------YGSVGRKG 1662
              G  G++G +GE G  GE GA G P   GP G QG  G PG           G  G  G
Sbjct: 1376 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1435

Query: 1663 AKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            A GQ+G PG  GP G  G  G PG  G KG  G +   G PGE G  G+ G PG +G  G
Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1495

Query: 1723 AKG 1725
            AKG
Sbjct: 1496 AKG 1498



 Score =  254 bits (650), Expect = 5e-67
 Identities = 150/340 (44%), Positives = 173/340 (50%), Gaps = 21/340 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEG------YLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G MG PGPPG RGP G  G++G       +G  G  GE+G PG  G  G  G  G  
Sbjct: 1225 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1284

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDR 1502
            GPKG RG  G+ G  G  G  G  G  GD+G    PG  G  GD G  G PG  G  G  
Sbjct: 1285 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1344

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G KG  GDPG PG       P G  GE G  G  G  GPPG  G+  +    G +G  G 
Sbjct: 1345 GDKGEDGDPGQPG-------PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1397

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGS 1622
            +G  G  GP G +G  G  GP+G RG  G  GE+G  G+ G  GPPGP G  G  G  G 
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1457

Query: 1623 QGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
             G+KGE G  G  G +G PG +G +G+ G PG  + G  GAKG  G PG +GP G  G P
Sbjct: 1458 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--TQGSPGAKGDGGIPGPAGPLGPPGPP 1515

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            G PG  G KG +G   S G  G+ G  G PGPPG  G  G
Sbjct: 1516 GLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  252 bits (644), Expect = 3e-66
 Identities = 153/374 (40%), Positives = 187/374 (50%), Gaps = 44/374 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G MG  G PG  G PG  G++G  G+ G  G RG  GP G  G  G  G  G  G R
Sbjct: 541  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 1452 GLNGQEGEVGENGIDGL---------NGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G+ G+ G  G+ G DGL          GE+G  G PG  G+ G  G  G  G RG PG+ 
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660

Query: 1503 GAKGLRGD------PGAPGVDSSIEGPTGLKGERGRQ------GRRGWPGPPGTPGSRRK 1550
            G +GL G       PG PG+ + ++GP G KG  G Q      G++G PGP G PG +  
Sbjct: 661  GPRGLLGPRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 719

Query: 1551 TAAHGRRGHTGPQGTAGIPGPD------------GLEGSLGLKGPQGP---RGEAGVKGE 1595
                G +G  G  G AG+PG D            G +G+LG  GPQGP    G  GVKG 
Sbjct: 720  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG- 1654
             G  G KG +G  G  G  G +G +G +G++GE G +G +G  G  GP+G  G  G PG 
Sbjct: 780  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839

Query: 1655 ---YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
                G  G+ G  G  G+PG  GPKG  G PG PG  G KGARG    AG PG  G  G 
Sbjct: 840  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG---VAGKPGPRGQRGP 896

Query: 1712 PGPPGRKGVKGAKG 1725
             GP G +G +G  G
Sbjct: 897  TGPRGSRGARGPTG 910



 Score =  250 bits (638), Expect = 1e-65
 Identities = 152/376 (40%), Positives = 181/376 (48%), Gaps = 16/376 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GGDG  G  G  G  G  G +G+ G+ G  G  G +G PGP GE+G  G  G  GP G  
Sbjct: 1177 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G  G +G  G  G  G  G  G KGE G+ G+ G PG+ G  G +G +G +G+ 
Sbjct: 1237 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1296

Query: 1512 GAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGS------------RRKTAAHGRR 1557
            G PG       +GP G  G +G  G  G+PG PG PG             + +    G+ 
Sbjct: 1297 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1356

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP G AG PGP G  G  G  G +G +GE G KGE G  G  G  GP GP G AG  
Sbjct: 1357 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPK 1676
            G  G +G  G  G+ G  GA G  GP G  G  G PG  G  G KG KG  G  G  GP 
Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1476

Query: 1677 GEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQ 1736
            GE G+ G  G  G +G+ G     G+PG  G  G PGPPG  G +G KG    ST    Q
Sbjct: 1477 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG-STGPAGQ 1535

Query: 1737 YVRDRSPGRHGKPECP 1752
                  PG  G P  P
Sbjct: 1536 KGDSGLPGPPGSPGPP 1551



 Score =  227 bits (578), Expect = 1e-58
 Identities = 136/317 (42%), Positives = 161/317 (50%), Gaps = 30/317 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +GG G  G+PG  G  GPPG  G  G  GE G  GE G PG  G  G KG  G  GPKGN
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 1451 RGL---------NGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGD 1501
             G           G+ G  G++G+ G  GE GD G PG  G  G+ G  G PGKRG PG 
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1379

Query: 1502 RGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTG 1561
             GA+G +G+ GA G ++  EGP G  G  G QG  G PGP G           G  G  G
Sbjct: 1380 AGAEGRQGEKGAKG-EAGAEGPPGKTGPVGPQGPAGKPGPEGL---------RGIPGPVG 1429

Query: 1562 PQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLG 1621
             QG  G  G DG  G +G  G  G +G+ G KGEKG  G  G  GPPG  GE G++G  G
Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 1622 SQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGD 1681
            +QG+ G  GD       G PGP G  G  G PG       G +G +G  G +GP G+ GD
Sbjct: 1490 TQGSPGAKGD------GGIPGPAGPLGPPGPPGL-----PGPQGPKGNKGSTGPAGQKGD 1538

Query: 1682 PGGPGETGLKGARGKMI 1698
             G PG  G  G  G++I
Sbjct: 1539 SGLPGPPGSPGPPGEVI 1555



 Score =  194 bits (492), Expect = 1e-48
 Identities = 133/339 (39%), Positives = 155/339 (45%), Gaps = 63/339 (18%)

Query: 1440 GCYGTKGPKGNRGLNGQEGEVGENG--IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
            G YG KG KG       E  V E G  ++G  G  G  G+ G  G +G  G  G PG RG
Sbjct: 432  GAYGEKGQKG-------EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRG 484

Query: 1498 TPGDRGAKGLRGDPGAPGV---------DSSIEGPT-----------------GLKGERG 1531
             PG  G  G  G PG PG              +GPT                  L+G  G
Sbjct: 485  PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG 544

Query: 1532 RQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD---------------GLEG 1576
              G  G PGP G PGS       G  G  GP+G  G PGP                G+ G
Sbjct: 545  PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
              G KG +G  G  G+ G+KG  G +GPQGPPGP G+ G +G  G  G +G PG+ G +G
Sbjct: 605  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664

Query: 1637 AVGFPGPRGLQGNDGSPGYGSV-GRKGAKGQEGFPGESGPKGEIGDPG-----GP----G 1686
             +   GPRG  G  G PG   V G  G KG  G  GE GP G+ G+PG     GP    G
Sbjct: 665  LL---GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 721

Query: 1687 ETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G KG +GK   AGLPG  G PG PG  G+ G KGA G
Sbjct: 722  PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 760



 Score =  157 bits (398), Expect = 9e-38
 Identities = 104/282 (36%), Positives = 120/282 (42%), Gaps = 55/282 (19%)

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            G  G KG +G+P        +EGP G  G  G  G  G  GP G PG        GR G 
Sbjct: 432  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 491

Query: 1560 TGPQGTAGIP---------------------------------------GPDGLEGSLGL 1580
             G  G  G P                                       GP G  G  G 
Sbjct: 492  PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 551

Query: 1581 KGPQGPRGEAGVKGEKGGVGSKGP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGA 1637
             GP G  G +G KGE G  G +GP   QGPPGP G+ G +GR G+ G +G PG+ G KG 
Sbjct: 552  PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 611

Query: 1638 VGFP------------GPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             GF             G RG QG  G PG  G  G  G  G  G PGE+GP+G +G  G 
Sbjct: 612  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 671

Query: 1685 PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG  G  G  G     G  G MG  GEPGPPG++G  G +GL
Sbjct: 672  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713



 Score =  112 bits (280), Expect = 4e-24
 Identities = 78/224 (34%), Positives = 94/224 (41%), Gaps = 47/224 (20%)

Query: 1542 PGTPGSRRKTAA----HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKG 1597
            PG P     T      HG  G  G +G   +  P  L     ++GP GP G AG+ G  G
Sbjct: 415  PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-----VEGPPGPAGPAGIMGPPG 469

Query: 1598 GVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDL----------GEKGAV--------- 1638
              G  GP G PG  G  G  G  G+ G  G PG +          G KG           
Sbjct: 470  LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 529

Query: 1639 -----------GFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
                       G PGP GL G  G    G  G  GAKG+ G PG  GP+G  G PG  G+
Sbjct: 530  AILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 587

Query: 1688 TGLKGARGKMISAGLPGEMGSPGE------PGPPGRKGVKGAKG 1725
             G +G  G     G+PGE G+ G+      PG PG KG +G +G
Sbjct: 588  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 53/132 (40%), Positives = 66/132 (50%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG  G+ GPPG  G  G  G +G  G +G  G  G  G  G  G +G KG+R
Sbjct: 1426 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1485

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G +G  G  G  G+ G  G  G PG  G  G +G +G+ G  G  G +G  GL G P
Sbjct: 1486 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1545

Query: 1512 GAPGVDSSIEGP 1523
            G+PG    +  P
Sbjct: 1546 GSPGPPGEVIQP 1557



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 22/101 (21%)

Query: 1654 GYGSVGRKGAKGQ----------EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLP 1703
            G+G+ G KG KG+          EG PG +GP G +G PG  G TG             P
Sbjct: 430  GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP------------P 477

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPG 1744
            G+ G  G PG PG  G  G  G          +Y  D S G
Sbjct: 478  GDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 518


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  270 bits (690), Expect = 1e-71
 Identities = 152/358 (42%), Positives = 183/358 (51%), Gaps = 24/358 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPG +GP G+ G  G  G +G+ G +G+ G  GE G  G  G  G KG+R
Sbjct: 700  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 759

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  GQ G  GE+G +G  G  G  G PG  G+ G++G  G PG  G PG +G KG  G P
Sbjct: 760  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819

Query: 1512 GAPGVDSSI--------------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRR 1557
            G PG +                  GPTG +G RG +G  G PGP GT G        G R
Sbjct: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879

Query: 1558 GHTGPQGTAGIPGP---------DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP 1608
            G  GPQG  G PGP         DGL G  G +G  G +G+ G  G  G VG +GP G  
Sbjct: 880  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 939

Query: 1609 GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQE 1667
            GP GE G+ G  G  G +G PG  G++GA G PGP+G+ G DG  G  G  G +G  G +
Sbjct: 940  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 999

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G PG  G +G  G PG  G  G +G+ G     GLPG  G  G PGP G KG  G KG
Sbjct: 1000 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057



 Score =  265 bits (677), Expect = 4e-70
 Identities = 156/346 (45%), Positives = 179/346 (51%), Gaps = 17/346 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GG+G  G PGP G  G  G  G+ G +G  G  G +G PGP GE+G  G  G +GP G  
Sbjct: 1006 GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1065

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G+ G  G  G  G  G  GE GD G    PG+KG KGD+G  G PG  G  G  GA G+ 
Sbjct: 1066 GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1125

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH---TGPQGT 1565
            G  G PG      G  G+ G++G +G RG+PGPPG  G +      G +G     GP G 
Sbjct: 1126 GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G PGP G +G  G  GPQGP G  G  G  G  G  G  G PGP GEAG  G  G +G 
Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241

Query: 1626 KGE---PGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGD 1681
            KGE   PG  G  GA G PG  G +GN G  G+ G  G  G  G  G  G  G KGE GD
Sbjct: 1242 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1301

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            PG PG  G  G  G     G PG+ G PG  G  GR+G KGAKG A
Sbjct: 1302 PGQPGPPGPSGEAG---PPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344



 Score =  261 bits (667), Expect = 6e-69
 Identities = 153/349 (43%), Positives = 183/349 (52%), Gaps = 21/349 (6%)

Query: 1395 GTMGDPGPPGKRGP------PGFKGSEGYLGEEGIAGE---RGAPGPVGEQGTKGCYGTK 1445
            G  G PG PG++GP      PGF G+ G  G  G+AG+   RG  GP G +G++G  G  
Sbjct: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 858

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  G +G +G +G  G  G  G  G QG  G PG KG  G  G  G PG  G  G+ G +
Sbjct: 859  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918

Query: 1506 GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G  G PG  GV    +GPTG  G  G +G  G PGPPG  G        G +G  GPQG 
Sbjct: 919  GKTGPPGPGGVVGP-QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
            +G  GP GL G  G +G  G +G  G+KG +G  G  GP G PG  G AG  G +G  G 
Sbjct: 978  SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037

Query: 1626 ---KGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
               +G PG  GEKGA G  GP+G  G DG    G VG  G  G  G PGE G KGEIG+P
Sbjct: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--QGPVGLPGPAGPAGSPGEDGDKGEIGEP 1095

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSP------GEPGPPGRKGVKGAKG 1725
            G  G  G KG  G     GL G +G+P      GEPGP G++G+ G KG
Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144



 Score =  261 bits (667), Expect = 6e-69
 Identities = 160/390 (41%), Positives = 194/390 (49%), Gaps = 54/390 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGS---------------------EGYLGEEGIAGERGA 1429
            +G  G  G PGPPGK G PG  G                      +G  GE G  GERG 
Sbjct: 888  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 947

Query: 1430 PGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE---KGD 1486
            PGP G  G +G  G  G +G +G  G +G  G++G  GL G  G+ GLPG +G    KG 
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 1487 EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP----- 1541
            EG QG PG  G+PG+RG+ G  G  G PG     +GP G  GE+G  G +G  GP     
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKGPQGPAGRDG 1066

Query: 1542 ----------------PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG 1585
                            PG  G + +    G++G  G +G  G PGP GL+G +G  G  G
Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126

Query: 1586 PRGEAGVKGEKGGVGSKGPQGP---PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPG 1642
              GE G +G++G  G KG +G    PGP G  G QG  G  G KGE GD+G  G  G PG
Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186

Query: 1643 PRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL---KGARGKMIS 1699
            PRG QG +G+   G  G  G+ G  G  GE G  GE G+PG PGE G+   KG RG+   
Sbjct: 1187 PRGPQGPNGAD--GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244

Query: 1700 AGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            AG PG  G PG  GPPG  G KG  G   F
Sbjct: 1245 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274



 Score =  257 bits (656), Expect = 1e-67
 Identities = 164/416 (39%), Positives = 199/416 (47%), Gaps = 81/416 (19%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQ----------GTKGC 1441
            G  G MG PG  G  GPPG  G  G  G  G+ G  G PGP G            G+KG 
Sbjct: 409  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 468

Query: 1442 -----------------YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEK 1484
                                +GP G  GL G+ G VG  G  G  GE GD G  G +G +
Sbjct: 469  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 528

Query: 1485 GDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGT 1544
            G  G  G PGKRG PG  G +G+ G+PGA G D   +G  GL G++G +G RG  GPPG 
Sbjct: 529  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKG-DRGFDGLPGLPGDKGHRGERGPQGPPGP 587

Query: 1545 PGS------------RRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGE 1589
            PG             R      G RG  GP+GT G PG  G+   +G  G KG  GP+GE
Sbjct: 588  PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 647

Query: 1590 AGVKGEKGGVGSKG---PQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGA 1637
             G  G++G  G +G   PQGP GP GE G QG+ G           G+ G+ G  GEKGA
Sbjct: 648  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 707

Query: 1638 ---------VGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFP---------------GES 1673
                     +G+PGPRG++G DG  G    G KG KG++GFP               G+ 
Sbjct: 708  LGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            GP+GE G  G  G  G  G  G    AG  G++G PG PG PGR+G KG+ G   F
Sbjct: 766  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 821



 Score =  256 bits (655), Expect = 1e-67
 Identities = 157/395 (39%), Positives = 191/395 (48%), Gaps = 57/395 (14%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERG---APGPVGEQGTKGCYGTK 1445
            G  G  G PGP   PGKRG PG  G  G  GE G  G+RG    PG  G++G +G  G +
Sbjct: 523  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GP G  G +G  GE GE G  GL GE G  GL G +G  G  G  G  G  G PG +G  
Sbjct: 583  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 642

Query: 1506 GLRGDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPG------PPGTPGSRRKT 1551
            G +G+PG PG   +         +GP G  GE+G QG+ G  G      PPG PG   ++
Sbjct: 643  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGS---LGLKGPQGPRGEAGVKGEKGGVGSKG----- 1603
               G  G  GPQG  G PGP G++G+    GLKG +G +GE G  G KG +G KG     
Sbjct: 703  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 762

Query: 1604 -------------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
                               P G PGP G+AG +G+LG  G  G PG  G KG+ GFPG  
Sbjct: 763  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 822

Query: 1645 GLQGNDGSPGY----------GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            G  G  G+ G           G  G +G++G  G  G+ GPKG  G  G PG  G +G +
Sbjct: 823  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 882

Query: 1695 GKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            G     G PG  G PG PG  G  G  G +G   F
Sbjct: 883  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/363 (42%), Positives = 188/363 (51%), Gaps = 35/363 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  G  G+ GPPG  G +G +G  GIAG  G PGP G+QG    +G KG +G 
Sbjct: 1092 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM---FGQKGDEGA 1148

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNG------LPGRKGEKGDEGSQGSPGKRGTPG---- 1500
            RG  G  G +G  G+ G  GE+G+NG       PG  G +G +G  G+ G +G PG    
Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208

Query: 1501 -----DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG 1555
                 ++G  G  G+PG PG ++ + GP   KGERG +G  G PG  G PG++      G
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPG-EAGVGGP---KGERGEKGEAGPPGAAGPPGAKGPPGDDG 1264

Query: 1556 RRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAG 1615
             +G+ GP G  G PGP G  G  G  G  G +GE G  G+ G  G  G  GPPGP G+ G
Sbjct: 1265 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1324

Query: 1616 NQGRLGSQGNKGEPGDLGEKGAVGFP---GPRGLQGNDGSPG----------YGSVGRKG 1662
              G  G++G +GE G  GE GA G P   GP G QG  G PG           G  G  G
Sbjct: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384

Query: 1663 AKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            A GQ+G PG  GP G  G  G PG  G KG  G +   G PGE G  G+ G PG +G  G
Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444

Query: 1723 AKG 1725
            AKG
Sbjct: 1445 AKG 1447



 Score =  254 bits (650), Expect = 5e-67
 Identities = 150/340 (44%), Positives = 173/340 (50%), Gaps = 21/340 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEG------YLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G MG PGPPG RGP G  G++G       +G  G  GE+G PG  G  G  G  G  
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDR 1502
            GPKG RG  G+ G  G  G  G  G  GD+G    PG  G  GD G  G PG  G  G  
Sbjct: 1234 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G KG  GDPG PG       P G  GE G  G  G  GPPG  G+  +    G +G  G 
Sbjct: 1294 GDKGEDGDPGQPG-------PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGS 1622
            +G  G  GP G +G  G  GP+G RG  G  GE+G  G+ G  GPPGP G  G  G  G 
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406

Query: 1623 QGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
             G+KGE G  G  G +G PG +G +G+ G PG  + G  GAKG  G PG +GP G  G P
Sbjct: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--TQGSPGAKGDGGIPGPAGPLGPPGPP 1464

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            G PG  G KG +G   S G  G+ G  G PGPPG  G  G
Sbjct: 1465 GLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  252 bits (644), Expect = 3e-66
 Identities = 153/374 (40%), Positives = 187/374 (50%), Gaps = 44/374 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G MG  G PG  G PG  G++G  G+ G  G RG  GP G  G  G  G  G  G R
Sbjct: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549

Query: 1452 GLNGQEGEVGENGIDGL---------NGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G+ G+ G  G+ G DGL          GE+G  G PG  G+ G  G  G  G RG PG+ 
Sbjct: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609

Query: 1503 GAKGLRGD------PGAPGVDSSIEGPTGLKGERGRQ------GRRGWPGPPGTPGSRRK 1550
            G +GL G       PG PG+ + ++GP G KG  G Q      G++G PGP G PG +  
Sbjct: 610  GPRGLLGPRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 668

Query: 1551 TAAHGRRGHTGPQGTAGIPGPD------------GLEGSLGLKGPQGP---RGEAGVKGE 1595
                G +G  G  G AG+PG D            G +G+LG  GPQGP    G  GVKG 
Sbjct: 669  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG- 1654
             G  G KG +G  G  G  G +G +G +G++GE G +G +G  G  GP+G  G  G PG 
Sbjct: 729  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788

Query: 1655 ---YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
                G  G+ G  G  G+PG  GPKG  G PG PG  G KGARG    AG PG  G  G 
Sbjct: 789  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG---VAGKPGPRGQRGP 845

Query: 1712 PGPPGRKGVKGAKG 1725
             GP G +G +G  G
Sbjct: 846  TGPRGSRGARGPTG 859



 Score =  250 bits (638), Expect = 1e-65
 Identities = 152/376 (40%), Positives = 181/376 (48%), Gaps = 16/376 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GGDG  G  G  G  G  G +G+ G+ G  G  G +G PGP GE+G  G  G  GP G  
Sbjct: 1126 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1185

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G  G +G  G  G  G  G  G KGE G+ G+ G PG+ G  G +G +G +G+ 
Sbjct: 1186 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1245

Query: 1512 GAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGS------------RRKTAAHGRR 1557
            G PG       +GP G  G +G  G  G+PG PG PG             + +    G+ 
Sbjct: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP G AG PGP G  G  G  G +G +GE G KGE G  G  G  GP GP G AG  
Sbjct: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPK 1676
            G  G +G  G  G+ G  GA G  GP G  G  G PG  G  G KG KG  G  G  GP 
Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425

Query: 1677 GEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQ 1736
            GE G+ G  G  G +G+ G     G+PG  G  G PGPPG  G +G KG    ST    Q
Sbjct: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG-STGPAGQ 1484

Query: 1737 YVRDRSPGRHGKPECP 1752
                  PG  G P  P
Sbjct: 1485 KGDSGLPGPPGSPGPP 1500



 Score =  227 bits (578), Expect = 1e-58
 Identities = 136/317 (42%), Positives = 161/317 (50%), Gaps = 30/317 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +GG G  G+PG  G  GPPG  G  G  GE G  GE G PG  G  G KG  G  GPKGN
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 1451 RGL---------NGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGD 1501
             G           G+ G  G++G+ G  GE GD G PG  G  G+ G  G PGKRG PG 
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1328

Query: 1502 RGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTG 1561
             GA+G +G+ GA G ++  EGP G  G  G QG  G PGP G           G  G  G
Sbjct: 1329 AGAEGRQGEKGAKG-EAGAEGPPGKTGPVGPQGPAGKPGPEGL---------RGIPGPVG 1378

Query: 1562 PQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLG 1621
             QG  G  G DG  G +G  G  G +G+ G KGEKG  G  G  GPPG  GE G++G  G
Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 1622 SQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGD 1681
            +QG+ G  GD       G PGP G  G  G PG       G +G +G  G +GP G+ GD
Sbjct: 1439 TQGSPGAKGD------GGIPGPAGPLGPPGPPGL-----PGPQGPKGNKGSTGPAGQKGD 1487

Query: 1682 PGGPGETGLKGARGKMI 1698
             G PG  G  G  G++I
Sbjct: 1488 SGLPGPPGSPGPPGEVI 1504



 Score =  194 bits (492), Expect = 1e-48
 Identities = 133/339 (39%), Positives = 155/339 (45%), Gaps = 63/339 (18%)

Query: 1440 GCYGTKGPKGNRGLNGQEGEVGENG--IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
            G YG KG KG       E  V E G  ++G  G  G  G+ G  G +G  G  G PG RG
Sbjct: 381  GAYGEKGQKG-------EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRG 433

Query: 1498 TPGDRGAKGLRGDPGAPGV---------DSSIEGPT-----------------GLKGERG 1531
             PG  G  G  G PG PG              +GPT                  L+G  G
Sbjct: 434  PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG 493

Query: 1532 RQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD---------------GLEG 1576
              G  G PGP G PGS       G  G  GP+G  G PGP                G+ G
Sbjct: 494  PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
              G KG +G  G  G+ G+KG  G +GPQGPPGP G+ G +G  G  G +G PG+ G +G
Sbjct: 554  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613

Query: 1637 AVGFPGPRGLQGNDGSPGYGSV-GRKGAKGQEGFPGESGPKGEIGDPG-----GP----G 1686
             +   GPRG  G  G PG   V G  G KG  G  GE GP G+ G+PG     GP    G
Sbjct: 614  LL---GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 670

Query: 1687 ETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G KG +GK   AGLPG  G PG PG  G+ G KGA G
Sbjct: 671  PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 709



 Score =  157 bits (398), Expect = 9e-38
 Identities = 104/282 (36%), Positives = 120/282 (42%), Gaps = 55/282 (19%)

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            G  G KG +G+P        +EGP G  G  G  G  G  GP G PG        GR G 
Sbjct: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440

Query: 1560 TGPQGTAGIP---------------------------------------GPDGLEGSLGL 1580
             G  G  G P                                       GP G  G  G 
Sbjct: 441  PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 500

Query: 1581 KGPQGPRGEAGVKGEKGGVGSKGP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGA 1637
             GP G  G +G KGE G  G +GP   QGPPGP G+ G +GR G+ G +G PG+ G KG 
Sbjct: 501  PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 560

Query: 1638 VGFP------------GPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             GF             G RG QG  G PG  G  G  G  G  G PGE+GP+G +G  G 
Sbjct: 561  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620

Query: 1685 PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG  G  G  G     G  G MG  GEPGPPG++G  G +GL
Sbjct: 621  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662



 Score =  112 bits (280), Expect = 4e-24
 Identities = 78/224 (34%), Positives = 94/224 (41%), Gaps = 47/224 (20%)

Query: 1542 PGTPGSRRKTAA----HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKG 1597
            PG P     T      HG  G  G +G   +  P  L     ++GP GP G AG+ G  G
Sbjct: 364  PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-----VEGPPGPAGPAGIMGPPG 418

Query: 1598 GVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDL----------GEKGAV--------- 1638
              G  GP G PG  G  G  G  G+ G  G PG +          G KG           
Sbjct: 419  LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 478

Query: 1639 -----------GFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
                       G PGP GL G  G    G  G  GAKG+ G PG  GP+G  G PG  G+
Sbjct: 479  AILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 536

Query: 1688 TGLKGARGKMISAGLPGEMGSPGE------PGPPGRKGVKGAKG 1725
             G +G  G     G+PGE G+ G+      PG PG KG +G +G
Sbjct: 537  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 53/132 (40%), Positives = 66/132 (50%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG  G+ GPPG  G  G  G +G  G +G  G  G  G  G  G +G KG+R
Sbjct: 1375 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1434

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G +G  G  G  G+ G  G  G PG  G  G +G +G+ G  G  G +G  GL G P
Sbjct: 1435 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1494

Query: 1512 GAPGVDSSIEGP 1523
            G+PG    +  P
Sbjct: 1495 GSPGPPGEVIQP 1506



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 22/101 (21%)

Query: 1654 GYGSVGRKGAKGQ----------EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLP 1703
            G+G+ G KG KG+          EG PG +GP G +G PG  G TG             P
Sbjct: 379  GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP------------P 426

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPG 1744
            G+ G  G PG PG  G  G  G          +Y  D S G
Sbjct: 427  GDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 467


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  270 bits (690), Expect = 1e-71
 Identities = 152/358 (42%), Positives = 183/358 (51%), Gaps = 24/358 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  GPPG +GP G+ G  G  G +G+ G +G+ G  GE G  G  G  G KG+R
Sbjct: 739  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 798

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  GQ G  GE+G +G  G  G  G PG  G+ G++G  G PG  G PG +G KG  G P
Sbjct: 799  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858

Query: 1512 GAPGVDSSI--------------EGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRR 1557
            G PG +                  GPTG +G RG +G  G PGP GT G        G R
Sbjct: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918

Query: 1558 GHTGPQGTAGIPGP---------DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP 1608
            G  GPQG  G PGP         DGL G  G +G  G +G+ G  G  G VG +GP G  
Sbjct: 919  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 978

Query: 1609 GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQE 1667
            GP GE G+ G  G  G +G PG  G++GA G PGP+G+ G DG  G  G  G +G  G +
Sbjct: 979  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1038

Query: 1668 GFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G PG  G +G  G PG  G  G +G+ G     GLPG  G  G PGP G KG  G KG
Sbjct: 1039 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096



 Score =  265 bits (677), Expect = 4e-70
 Identities = 156/346 (45%), Positives = 179/346 (51%), Gaps = 17/346 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GG+G  G PGP G  G  G  G+ G +G  G  G +G PGP GE+G  G  G +GP G  
Sbjct: 1045 GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1104

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G+ G  G  G  G  G  GE GD G    PG+KG KGD+G  G PG  G  G  GA G+ 
Sbjct: 1105 GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1164

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH---TGPQGT 1565
            G  G PG      G  G+ G++G +G RG+PGPPG  G +      G +G     GP G 
Sbjct: 1165 GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
             G PGP G +G  G  GPQGP G  G  G  G  G  G  G PGP GEAG  G  G +G 
Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280

Query: 1626 KGE---PGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGD 1681
            KGE   PG  G  GA G PG  G +GN G  G+ G  G  G  G  G  G  G KGE GD
Sbjct: 1281 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1340

Query: 1682 PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
            PG PG  G  G  G     G PG+ G PG  G  GR+G KGAKG A
Sbjct: 1341 PGQPGPPGPSGEAG---PPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383



 Score =  261 bits (667), Expect = 6e-69
 Identities = 153/349 (43%), Positives = 183/349 (52%), Gaps = 21/349 (6%)

Query: 1395 GTMGDPGPPGKRGP------PGFKGSEGYLGEEGIAGE---RGAPGPVGEQGTKGCYGTK 1445
            G  G PG PG++GP      PGF G+ G  G  G+AG+   RG  GP G +G++G  G  
Sbjct: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 897

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            G  G +G +G +G  G  G  G  G QG  G PG KG  G  G  G PG  G  G+ G +
Sbjct: 898  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957

Query: 1506 GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGT 1565
            G  G PG  GV    +GPTG  G  G +G  G PGPPG  G        G +G  GPQG 
Sbjct: 958  GKTGPPGPGGVVGP-QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGN 1625
            +G  GP GL G  G +G  G +G  G+KG +G  G  GP G PG  G AG  G +G  G 
Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076

Query: 1626 ---KGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
               +G PG  GEKGA G  GP+G  G DG    G VG  G  G  G PGE G KGEIG+P
Sbjct: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--QGPVGLPGPAGPAGSPGEDGDKGEIGEP 1134

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSP------GEPGPPGRKGVKGAKG 1725
            G  G  G KG  G     GL G +G+P      GEPGP G++G+ G KG
Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183



 Score =  261 bits (667), Expect = 6e-69
 Identities = 160/390 (41%), Positives = 194/390 (49%), Gaps = 54/390 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGS---------------------EGYLGEEGIAGERGA 1429
            +G  G  G PGPPGK G PG  G                      +G  GE G  GERG 
Sbjct: 927  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 986

Query: 1430 PGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE---KGD 1486
            PGP G  G +G  G  G +G +G  G +G  G++G  GL G  G+ GLPG +G    KG 
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 1487 EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP----- 1541
            EG QG PG  G+PG+RG+ G  G  G PG     +GP G  GE+G  G +G  GP     
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKGPQGPAGRDG 1105

Query: 1542 ----------------PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG 1585
                            PG  G + +    G++G  G +G  G PGP GL+G +G  G  G
Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165

Query: 1586 PRGEAGVKGEKGGVGSKGPQGP---PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPG 1642
              GE G +G++G  G KG +G    PGP G  G QG  G  G KGE GD+G  G  G PG
Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225

Query: 1643 PRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL---KGARGKMIS 1699
            PRG QG +G+   G  G  G+ G  G  GE G  GE G+PG PGE G+   KG RG+   
Sbjct: 1226 PRGPQGPNGAD--GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283

Query: 1700 AGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            AG PG  G PG  GPPG  G KG  G   F
Sbjct: 1284 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313



 Score =  257 bits (656), Expect = 1e-67
 Identities = 164/416 (39%), Positives = 199/416 (47%), Gaps = 81/416 (19%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQ----------GTKGC 1441
            G  G MG PG  G  GPPG  G  G  G  G+ G  G PGP G            G+KG 
Sbjct: 448  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 507

Query: 1442 -----------------YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEK 1484
                                +GP G  GL G+ G VG  G  G  GE GD G  G +G +
Sbjct: 508  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 567

Query: 1485 GDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGT 1544
            G  G  G PGKRG PG  G +G+ G+PGA G D   +G  GL G++G +G RG  GPPG 
Sbjct: 568  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKG-DRGFDGLPGLPGDKGHRGERGPQGPPGP 626

Query: 1545 PGS------------RRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGE 1589
            PG             R      G RG  GP+GT G PG  G+   +G  G KG  GP+GE
Sbjct: 627  PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 686

Query: 1590 AGVKGEKGGVGSKG---PQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGA 1637
             G  G++G  G +G   PQGP GP GE G QG+ G           G+ G+ G  GEKGA
Sbjct: 687  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 746

Query: 1638 ---------VGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFP---------------GES 1673
                     +G+PGPRG++G DG  G    G KG KG++GFP               G+ 
Sbjct: 747  LGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            GP+GE G  G  G  G  G  G    AG  G++G PG PG PGR+G KG+ G   F
Sbjct: 805  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 860



 Score =  256 bits (655), Expect = 1e-67
 Identities = 157/395 (39%), Positives = 191/395 (48%), Gaps = 57/395 (14%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERG---APGPVGEQGTKGCYGTK 1445
            G  G  G PGP   PGKRG PG  G  G  GE G  G+RG    PG  G++G +G  G +
Sbjct: 562  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GP G  G +G  GE GE G  GL GE G  GL G +G  G  G  G  G  G PG +G  
Sbjct: 622  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 681

Query: 1506 GLRGDPGAPGVDSSI--------EGPTGLKGERGRQGRRGWPG------PPGTPGSRRKT 1551
            G +G+PG PG   +         +GP G  GE+G QG+ G  G      PPG PG   ++
Sbjct: 682  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGS---LGLKGPQGPRGEAGVKGEKGGVGSKG----- 1603
               G  G  GPQG  G PGP G++G+    GLKG +G +GE G  G KG +G KG     
Sbjct: 742  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 801

Query: 1604 -------------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
                               P G PGP G+AG +G+LG  G  G PG  G KG+ GFPG  
Sbjct: 802  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 861

Query: 1645 GLQGNDGSPGY----------GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            G  G  G+ G           G  G +G++G  G  G+ GPKG  G  G PG  G +G +
Sbjct: 862  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 921

Query: 1695 GKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            G     G PG  G PG PG  G  G  G +G   F
Sbjct: 922  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 956



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/363 (42%), Positives = 188/363 (51%), Gaps = 35/363 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG  G  G  G  G+ GPPG  G +G +G  GIAG  G PGP G+QG    +G KG +G 
Sbjct: 1131 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM---FGQKGDEGA 1187

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNG------LPGRKGEKGDEGSQGSPGKRGTPG---- 1500
            RG  G  G +G  G+ G  GE+G+NG       PG  G +G +G  G+ G +G PG    
Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247

Query: 1501 -----DRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHG 1555
                 ++G  G  G+PG PG ++ + GP   KGERG +G  G PG  G PG++      G
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPG-EAGVGGP---KGERGEKGEAGPPGAAGPPGAKGPPGDDG 1303

Query: 1556 RRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAG 1615
             +G+ GP G  G PGP G  G  G  G  G +GE G  G+ G  G  G  GPPGP G+ G
Sbjct: 1304 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1363

Query: 1616 NQGRLGSQGNKGEPGDLGEKGAVGFP---GPRGLQGNDGSPG----------YGSVGRKG 1662
              G  G++G +GE G  GE GA G P   GP G QG  G PG           G  G  G
Sbjct: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423

Query: 1663 AKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            A GQ+G PG  GP G  G  G PG  G KG  G +   G PGE G  G+ G PG +G  G
Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483

Query: 1723 AKG 1725
            AKG
Sbjct: 1484 AKG 1486



 Score =  254 bits (650), Expect = 5e-67
 Identities = 150/340 (44%), Positives = 173/340 (50%), Gaps = 21/340 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEG------YLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G MG PGPPG RGP G  G++G       +G  G  GE+G PG  G  G  G  G  
Sbjct: 1213 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1272

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDR 1502
            GPKG RG  G+ G  G  G  G  G  GD+G    PG  G  GD G  G PG  G  G  
Sbjct: 1273 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1332

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G KG  GDPG PG       P G  GE G  G  G  GPPG  G+  +    G +G  G 
Sbjct: 1333 GDKGEDGDPGQPG-------PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGS 1622
            +G  G  GP G +G  G  GP+G RG  G  GE+G  G+ G  GPPGP G  G  G  G 
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445

Query: 1623 QGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDP 1682
             G+KGE G  G  G +G PG +G +G+ G PG  + G  GAKG  G PG +GP G  G P
Sbjct: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--TQGSPGAKGDGGIPGPAGPLGPPGPP 1503

Query: 1683 GGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
            G PG  G KG +G   S G  G+ G  G PGPPG  G  G
Sbjct: 1504 GLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  252 bits (644), Expect = 3e-66
 Identities = 153/374 (40%), Positives = 187/374 (50%), Gaps = 44/374 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G MG  G PG  G PG  G++G  G+ G  G RG  GP G  G  G  G  G  G R
Sbjct: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 1452 GLNGQEGEVGENGIDGL---------NGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G+ G+ G  G+ G DGL          GE+G  G PG  G+ G  G  G  G RG PG+ 
Sbjct: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648

Query: 1503 GAKGLRGD------PGAPGVDSSIEGPTGLKGERGRQ------GRRGWPGPPGTPGSRRK 1550
            G +GL G       PG PG+ + ++GP G KG  G Q      G++G PGP G PG +  
Sbjct: 649  GPRGLLGPRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 707

Query: 1551 TAAHGRRGHTGPQGTAGIPGPD------------GLEGSLGLKGPQGP---RGEAGVKGE 1595
                G +G  G  G AG+PG D            G +G+LG  GPQGP    G  GVKG 
Sbjct: 708  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG- 1654
             G  G KG +G  G  G  G +G +G +G++GE G +G +G  G  GP+G  G  G PG 
Sbjct: 768  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827

Query: 1655 ---YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
                G  G+ G  G  G+PG  GPKG  G PG PG  G KGARG    AG PG  G  G 
Sbjct: 828  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG---VAGKPGPRGQRGP 884

Query: 1712 PGPPGRKGVKGAKG 1725
             GP G +G +G  G
Sbjct: 885  TGPRGSRGARGPTG 898



 Score =  250 bits (638), Expect = 1e-65
 Identities = 152/376 (40%), Positives = 181/376 (48%), Gaps = 16/376 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GGDG  G  G  G  G  G +G+ G+ G  G  G +G PGP GE+G  G  G  GP G  
Sbjct: 1165 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1224

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G  G +G  G  G  G  G  G KGE G+ G+ G PG+ G  G +G +G +G+ 
Sbjct: 1225 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1284

Query: 1512 GAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGS------------RRKTAAHGRR 1557
            G PG       +GP G  G +G  G  G+PG PG PG             + +    G+ 
Sbjct: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP G AG PGP G  G  G  G +G +GE G KGE G  G  G  GP GP G AG  
Sbjct: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPK 1676
            G  G +G  G  G+ G  GA G  GP G  G  G PG  G  G KG KG  G  G  GP 
Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464

Query: 1677 GEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQ 1736
            GE G+ G  G  G +G+ G     G+PG  G  G PGPPG  G +G KG    ST    Q
Sbjct: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG-STGPAGQ 1523

Query: 1737 YVRDRSPGRHGKPECP 1752
                  PG  G P  P
Sbjct: 1524 KGDSGLPGPPGSPGPP 1539



 Score =  227 bits (578), Expect = 1e-58
 Identities = 136/317 (42%), Positives = 161/317 (50%), Gaps = 30/317 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +GG G  G+PG  G  GPPG  G  G  GE G  GE G PG  G  G KG  G  GPKGN
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 1451 RGL---------NGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGD 1501
             G           G+ G  G++G+ G  GE GD G PG  G  G+ G  G PGKRG PG 
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1367

Query: 1502 RGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTG 1561
             GA+G +G+ GA G ++  EGP G  G  G QG  G PGP G           G  G  G
Sbjct: 1368 AGAEGRQGEKGAKG-EAGAEGPPGKTGPVGPQGPAGKPGPEGL---------RGIPGPVG 1417

Query: 1562 PQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLG 1621
             QG  G  G DG  G +G  G  G +G+ G KGEKG  G  G  GPPG  GE G++G  G
Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 1622 SQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGD 1681
            +QG+ G  GD       G PGP G  G  G PG       G +G +G  G +GP G+ GD
Sbjct: 1478 TQGSPGAKGD------GGIPGPAGPLGPPGPPGL-----PGPQGPKGNKGSTGPAGQKGD 1526

Query: 1682 PGGPGETGLKGARGKMI 1698
             G PG  G  G  G++I
Sbjct: 1527 SGLPGPPGSPGPPGEVI 1543



 Score =  194 bits (492), Expect = 1e-48
 Identities = 133/339 (39%), Positives = 155/339 (45%), Gaps = 63/339 (18%)

Query: 1440 GCYGTKGPKGNRGLNGQEGEVGENG--IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
            G YG KG KG       E  V E G  ++G  G  G  G+ G  G +G  G  G PG RG
Sbjct: 420  GAYGEKGQKG-------EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRG 472

Query: 1498 TPGDRGAKGLRGDPGAPGV---------DSSIEGPT-----------------GLKGERG 1531
             PG  G  G  G PG PG              +GPT                  L+G  G
Sbjct: 473  PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG 532

Query: 1532 RQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD---------------GLEG 1576
              G  G PGP G PGS       G  G  GP+G  G PGP                G+ G
Sbjct: 533  PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
              G KG +G  G  G+ G+KG  G +GPQGPPGP G+ G +G  G  G +G PG+ G +G
Sbjct: 593  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652

Query: 1637 AVGFPGPRGLQGNDGSPGYGSV-GRKGAKGQEGFPGESGPKGEIGDPG-----GP----G 1686
             +   GPRG  G  G PG   V G  G KG  G  GE GP G+ G+PG     GP    G
Sbjct: 653  LL---GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 709

Query: 1687 ETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G KG +GK   AGLPG  G PG PG  G+ G KGA G
Sbjct: 710  PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 748



 Score =  157 bits (398), Expect = 9e-38
 Identities = 104/282 (36%), Positives = 120/282 (42%), Gaps = 55/282 (19%)

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            G  G KG +G+P        +EGP G  G  G  G  G  GP G PG        GR G 
Sbjct: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479

Query: 1560 TGPQGTAGIP---------------------------------------GPDGLEGSLGL 1580
             G  G  G P                                       GP G  G  G 
Sbjct: 480  PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 539

Query: 1581 KGPQGPRGEAGVKGEKGGVGSKGP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGA 1637
             GP G  G +G KGE G  G +GP   QGPPGP G+ G +GR G+ G +G PG+ G KG 
Sbjct: 540  PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 599

Query: 1638 VGFP------------GPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             GF             G RG QG  G PG  G  G  G  G  G PGE+GP+G +G  G 
Sbjct: 600  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659

Query: 1685 PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            PG  G  G  G     G  G MG  GEPGPPG++G  G +GL
Sbjct: 660  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701



 Score =  112 bits (280), Expect = 4e-24
 Identities = 78/224 (34%), Positives = 94/224 (41%), Gaps = 47/224 (20%)

Query: 1542 PGTPGSRRKTAA----HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKG 1597
            PG P     T      HG  G  G +G   +  P  L     ++GP GP G AG+ G  G
Sbjct: 403  PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-----VEGPPGPAGPAGIMGPPG 457

Query: 1598 GVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDL----------GEKGAV--------- 1638
              G  GP G PG  G  G  G  G+ G  G PG +          G KG           
Sbjct: 458  LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 517

Query: 1639 -----------GFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
                       G PGP GL G  G    G  G  GAKG+ G PG  GP+G  G PG  G+
Sbjct: 518  AILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575

Query: 1688 TGLKGARGKMISAGLPGEMGSPGE------PGPPGRKGVKGAKG 1725
             G +G  G     G+PGE G+ G+      PG PG KG +G +G
Sbjct: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 53/132 (40%), Positives = 66/132 (50%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG  G+ GPPG  G  G  G +G  G +G  G  G  G  G  G +G KG+R
Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1473

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G +G  G  G  G+ G  G  G PG  G  G +G +G+ G  G  G +G  GL G P
Sbjct: 1474 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533

Query: 1512 GAPGVDSSIEGP 1523
            G+PG    +  P
Sbjct: 1534 GSPGPPGEVIQP 1545



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 22/101 (21%)

Query: 1654 GYGSVGRKGAKGQ----------EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLP 1703
            G+G+ G KG KG+          EG PG +GP G +G PG  G TG             P
Sbjct: 418  GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP------------P 465

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPG 1744
            G+ G  G PG PG  G  G  G          +Y  D S G
Sbjct: 466  GDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 506


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  266 bits (681), Expect = 1e-70
 Identities = 146/338 (43%), Positives = 179/338 (52%), Gaps = 12/338 (3%)

Query: 1400 PGPPGKRGPPGFKGSEGYLGE---EGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
            PGPPG  G PGFKG +G  G+   EG  G++G  GP G  G  G  G +G +G RG +G+
Sbjct: 566  PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 625

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
             G+ G+ G  G+ G  G  G PG  G  G  G+ G PG +G+PG  G  G +G  G PG+
Sbjct: 626  VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI 685

Query: 1517 -----DSSIEGPTGLKGERGRQGRRGWPGPPGT---PGSRRKTAAHGRRGHTGPQGTAGI 1568
                     +G  G  GE G+ G  G PGP G    PG +  T   G  G  G  G  G+
Sbjct: 686  PGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL 745

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
            PG +GL G  G  GP GP+G  G +G  G  GS G  G PGP G  G +G  G  G+ G 
Sbjct: 746  PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805

Query: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
            PG LG +G  G PG +G+ G +G PG  G  G KG +G  G  G+ GP G  G PG PG 
Sbjct: 806  PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI 865

Query: 1688 TGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G KG  G M   GLPGE G  G PGPPG+ G  G +G
Sbjct: 866  PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 903



 Score =  254 bits (648), Expect = 9e-67
 Identities = 165/421 (39%), Positives = 201/421 (47%), Gaps = 62/421 (14%)

Query: 1392 GGDGTMGDPGPPGKR--GPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGC--YGTKGP 1447
            G  G  G PGPPGK   G PG +GS G  G  G  G+RGAPG  G  G++G    G  GP
Sbjct: 452  GDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGP 511

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNG------------------------------L 1477
             G  G  G +G  G  G+ G  G QG  G                              L
Sbjct: 512  PGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGL 571

Query: 1478 PGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRG 1537
            PG  G KGD+G  G PG+ GT G +G  G  G PG PG    I GP G +GERG  G  G
Sbjct: 572  PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG----IAGPQGSQGERGADGEVG 627

Query: 1538 WPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAG---VKG 1594
              G  G PG        G  G  G  G AG  GP G++GS G +GP GP+G +G   + G
Sbjct: 628  QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687

Query: 1595 EKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRG------LQG 1648
            E+G  G  G  GPPG  G+AG  G  G +G +G PG  G  G  G PGPRG      L G
Sbjct: 688  EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 747

Query: 1649 NDGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPG 1704
             +G PG     G  G +G +G  G PG++G  G  G+PG  G  G KG++G+  S GLPG
Sbjct: 748  QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 807

Query: 1705 EMG------SPGEPGPPGRKGVKGAKGLASFSTCELIQYVR-DRSP----GRHGKPECPV 1753
             +G       PGE G PG++GV G  G   F        ++ D+ P    G+ G P  P 
Sbjct: 808  FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 867

Query: 1754 H 1754
            H
Sbjct: 868  H 868



 Score =  250 bits (638), Expect = 1e-65
 Identities = 157/371 (42%), Positives = 182/371 (49%), Gaps = 46/371 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ GP G  GPPG KG EG  G  G AG  GAPG VG  G  G  G+ G  G R
Sbjct: 365  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 424

Query: 1452 GLNGQEGEVGENGIDGLNG---------EQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  G++GE GE G  G  G         + G  GLPG  G    +G  G PG RG+PG  
Sbjct: 425  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLP 480

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G  G +GD GAPG    I G  G +G+ G  G  G PGP G PG +    + G  G  GP
Sbjct: 481  GPLGTKGDRGAPG----IPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 535

Query: 1563 QGTAG------------------------IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGG 1598
            QG AG                         PGP GL G  G KG +G  G+ G +G +G 
Sbjct: 536  QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK 595

Query: 1599 VGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG---- 1654
             G  GP G PGP G AG QG  G +G  GE G  G++G  G PG  G  GN G PG    
Sbjct: 596  KGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI 655

Query: 1655 YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G+ G  G +G  G  G  GP+G  G PG PGE G +G  GK    G PG+ G PG PGP
Sbjct: 656  AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 715

Query: 1715 PGRKGVKGAKG 1725
             G +G  G KG
Sbjct: 716  EGARGPPGFKG 726



 Score =  241 bits (615), Expect = 6e-63
 Identities = 155/379 (40%), Positives = 187/379 (49%), Gaps = 42/379 (11%)

Query: 1398 GDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQE 1457
            G+ GP G++G PG  G  G  G  G  G +G  GP G +G +G +G  G  GN G  G  
Sbjct: 347  GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 406

Query: 1458 GEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS---QGSPGKRGTPGDRGAKGLRGDPGAP 1514
            G  G +G  G  G  G  G PG+ GE+G++G+   +GSPG  G  GD GA GL G PG  
Sbjct: 407  GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK- 465

Query: 1515 GVDSS--IEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD 1572
            G D    + G  GL G  G +G RG PG PG+PGSR         G  GP G +G PG  
Sbjct: 466  GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDK 521

Query: 1573 GLEGSLGLKGPQGPRGEAGVKGEKG------------GVGSKGPQGPPG-PG--GEAGNQ 1617
            G  GS GL G  GP+G AG  G                V +  P GPPG PG  G  G++
Sbjct: 522  GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPK 1676
            G  G  G +G  G  GE G  G PGP G+ G  GS G  G+ G  G KG +G PG  G  
Sbjct: 582  GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641

Query: 1677 GEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQ 1736
            G  G+PG PG  G+ GA      AG PG  GSPG+ GPPG +G  G  G+          
Sbjct: 642  GPPGNPGPPGADGIAGA------AGPPGIQGSPGKEGPPGPQGPSGLPGIPG-------- 687

Query: 1737 YVRDRSPGRHGKPECPVHP 1755
               +   GR GKP  P  P
Sbjct: 688  --EEGKEGRDGKPGPPGEP 704



 Score =  239 bits (610), Expect = 2e-62
 Identities = 168/436 (38%), Positives = 196/436 (44%), Gaps = 92/436 (21%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG RG  G +G  G  GE+G AG  GAPG  G +G KG  G KG  G  
Sbjct: 253  GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP 312

Query: 1452 GLNGQEGEVGE----------------------NGIDGLNGEQGDNGLP------GRKGE 1483
            GL G  GE GE                       G  G  GE+GD GLP      GR GE
Sbjct: 313  GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 372

Query: 1484 KGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPG 1543
             G +G  G PG +G  G  GA G  G+PGAPG      GP+G  G  G  G RG PG  G
Sbjct: 373  LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG-HVGAPGPSGPPGSVGAPGLRGTPGKDG 431

Query: 1544 TPGSRRKTAAHGRRGHTGPQ---GTAGIPGP--------DGLEGSLGLKGPQGPRGEAGV 1592
              G +      G  G  GP+   G  G+PGP         GL GS GL GP G +G+ G 
Sbjct: 432  ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGA 491

Query: 1593 KGEKGGVGSKGP-----QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGF------- 1640
             G  G  GS+G       GPPGP G  G++G  GS+G  G PG  G  G  G        
Sbjct: 492  PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPG 551

Query: 1641 --------------PGPRGL------QGNDGSPG----YGSVGRKGAKGQEGFPGE---S 1673
                          PGP GL      +G+ G PG     G+ G+KG  G  G PG    +
Sbjct: 552  DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIA 611

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCE 1733
            GP+G  G+ G  GE G KG +G     G+PG MG PG PGPPG  G+ GA G        
Sbjct: 612  GPQGSQGERGADGEVGQKGDQG---HPGVPGFMGPPGNPGPPGADGIAGAAGPPGI---- 664

Query: 1734 LIQYVRDRSPGRHGKP 1749
                    SPG+ G P
Sbjct: 665  ------QGSPGKEGPP 674



 Score =  231 bits (588), Expect = 8e-60
 Identities = 146/376 (38%), Positives = 171/376 (45%), Gaps = 58/376 (15%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGP G RGPPGFKG  G  G  G  GE GA G  G++G  G  G  GP G +
Sbjct: 705  GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ 764

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPG---KRGTPGDRGAKGLR 1508
            G  G  G  G+NG  G  GE G +G PG+KG KG+ GS G PG    RG PG+ G KG+ 
Sbjct: 765  GPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVP 824

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G  G PG      G  G KGERG  G +G  GPPG  G        G +GHTG  G  G+
Sbjct: 825  GKEGVPGKP----GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 880

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGV----------------------------- 1599
            PG +G    +G  GP G  G  G++GE   +                             
Sbjct: 881  PGENG---PVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 937

Query: 1600 ---GSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYG 1656
                S+G  GPPGP G+ G  GR G  G  G PG  G +G  G  GP+G +G  G PG  
Sbjct: 938  YMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAP 997

Query: 1657 SVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPG 1716
             VG +G  G  G PG+ G  G   D       GL G         +PG  G  G  G PG
Sbjct: 998  GVGLRGEMGPPGIPGQPGEPGYAKD-------GLPG---------IPGPQGETGPAGHPG 1041

Query: 1717 RKGVKGAKGLASFSTC 1732
              G  G  G    S C
Sbjct: 1042 LPGPPGPPGQCDPSQC 1057



 Score =  220 bits (561), Expect = 1e-56
 Identities = 139/362 (38%), Positives = 169/362 (46%), Gaps = 11/362 (3%)

Query: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
            +G  GP  +R               G+    G PG  GE G  G  G +G  G +GL G+
Sbjct: 219  LGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGR 278

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
             GE GE G   L G  G  G+ G KG++G++G  G PG +G  G++G  G  G PG PG 
Sbjct: 279  PGEKGEAG---LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 335

Query: 1517 DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG 1576
             S       + GE+G +G +G PG PG PG + +    G +G TGP G  G  G  G  G
Sbjct: 336  TSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG 395

Query: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636
            + G  G  G  G  G  G  G VG+ G +G PG  GE G +G  G +G+ G  G  G+ G
Sbjct: 396  AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 455

Query: 1637 AVGFPGPRGLQGNDGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKG 1692
            A G PGP G +G DG PG     G  G  G KG  G PG  G  G  GDP G G  G  G
Sbjct: 456  APGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDP-GIGVAGPPG 513

Query: 1693 ARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELI--QYVRDRSPGRHGKPE 1750
              G     G PG  G PG PGP G  G  G   L S     L+      D  PG  G P 
Sbjct: 514  PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 573

Query: 1751 CP 1752
             P
Sbjct: 574  LP 575



 Score =  100 bits (249), Expect = 2e-20
 Identities = 66/177 (37%), Positives = 82/177 (46%), Gaps = 22/177 (12%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEG--------IAGERGAP------------ 1430
            +G  G  G+ GP G  GPPG  G  G  GE          I  E G              
Sbjct: 875  MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934

Query: 1431 GPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQ 1490
             P   + ++G  G  GP G  GL G+ G +GE G  G  G +G +G  G KGE+G +G  
Sbjct: 935  PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDP 994

Query: 1491 GSPGKRGTPGDRGAKGLRGDPGAPG-VDSSIEGPTGLKGERGRQGRRGWPGPPGTPG 1546
            G+PG  G  G+ G  G+ G PG PG     + G  G +GE G  G  G PGPPG PG
Sbjct: 995  GAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  266 bits (681), Expect = 1e-70
 Identities = 146/338 (43%), Positives = 179/338 (52%), Gaps = 12/338 (3%)

Query: 1400 PGPPGKRGPPGFKGSEGYLGE---EGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456
            PGPPG  G PGFKG +G  G+   EG  G++G  GP G  G  G  G +G +G RG +G+
Sbjct: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178

Query: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516
             G+ G+ G  G+ G  G  G PG  G  G  G+ G PG +G+PG  G  G +G  G PG+
Sbjct: 1179 VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI 1238

Query: 1517 -----DSSIEGPTGLKGERGRQGRRGWPGPPGT---PGSRRKTAAHGRRGHTGPQGTAGI 1568
                     +G  G  GE G+ G  G PGP G    PG +  T   G  G  G  G  G+
Sbjct: 1239 PGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL 1298

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE 1628
            PG +GL G  G  GP GP+G  G +G  G  GS G  G PGP G  G +G  G  G+ G 
Sbjct: 1299 PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358

Query: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGE 1687
            PG LG +G  G PG +G+ G +G PG  G  G KG +G  G  G+ GP G  G PG PG 
Sbjct: 1359 PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI 1418

Query: 1688 TGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G KG  G M   GLPGE G  G PGPPG+ G  G +G
Sbjct: 1419 PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456



 Score =  263 bits (672), Expect = 1e-69
 Identities = 175/448 (39%), Positives = 204/448 (45%), Gaps = 109/448 (24%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGF-------KGSEGYLG------EEGIAGERGAPGPVGEQG 1437
            IG  G +G PGP G++G  G        KG +G LG       +G  G RG PG +GE G
Sbjct: 501  IGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG 560

Query: 1438 TKGCYGTKGPKGNRGLNGQEGEV------GENGIDGLNGEQGDNGLPGRKGEKGDEGSQG 1491
              G  G +GP+G  GL G  G V      GE G  G  GE+G+ GL G  G+ GD G QG
Sbjct: 561  LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKT 1551
             PG  G  G +G KG  G  G PGV  S+    GLKGE+G  G RG  G PG PG+R   
Sbjct: 621  RPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680

Query: 1552 AAHGR---------RGHTGPQGTAGIPGPDGLE---GSLGLKGPQGPRGEAGVKGEKGGV 1599
               GR         RG  G  G  GIPG  GL+   G  G+ GP GP G  G+ GE G  
Sbjct: 681  GPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP 740

Query: 1600 GSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE------------------------- 1634
            G  GP GP GP G+ G  G  G  G KGEPG+ GE                         
Sbjct: 741  GKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEK 800

Query: 1635 -----KGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEG-------------------- 1668
                  GA GFPG RG +G+ G  G  G  G KG +G++G                    
Sbjct: 801  GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 860

Query: 1669 --FPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
               PGE GPKGE GDPG PGE GL+G          PGE+G  G  GPPG KG +GA G 
Sbjct: 861  PRMPGEQGPKGEKGDPGLPGEPGLQGR---------PGELGPQGPTGPPGAKGQEGAHG- 910

Query: 1727 ASFSTCELIQYVRDRSPGRHGKPECPVH 1754
                           +PG  G P  P H
Sbjct: 911  ---------------APGAAGNPGAPGH 923



 Score =  256 bits (654), Expect = 2e-67
 Identities = 157/367 (42%), Positives = 199/367 (54%), Gaps = 27/367 (7%)

Query: 1388 CKCIGGD-GTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERG----APGPVGEQGTKGCY 1442
            C C  G+ G MG  GP G  GP G  G+ G +G  G  GE+G     P   GE+G KG  
Sbjct: 476  CSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSL 535

Query: 1443 GTKGP---KGNRGLNGQEGEVGENGID---GLNGEQGDNGLPGRKGEKGDEGSQGSPGKR 1496
            G  GP    G++G+ G+ GE+GE G+    G+ G QG  GLPG  G  G  G QG  G++
Sbjct: 536  GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595

Query: 1497 GTPGDRGAKGLRGDPGAPG--VDSSIEGPTGLKGERGRQGRRGWPGPPGTPGS-RRKTAA 1553
            GT G++G +GL G PG PG        GP+G+ G +G +G  G  GPPG PGS  ++   
Sbjct: 596  GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655

Query: 1554 HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK------GPQGP 1607
             G +G  GP+G  G PGP G  G +G +G  GP G  G++G+KG +G        G QGP
Sbjct: 656  KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715

Query: 1608 PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQ 1666
            PGP G  G  G  GS G  GE G  G+ G  G  GP G  G +G PG  G+ G  G +G+
Sbjct: 716  PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGE 775

Query: 1667 EGFPGESGPKGEIGD------PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGV 1720
            +G PG+ G +GEIG+      PG  GE GL GA G     G  G+ G  GE G PG KG 
Sbjct: 776  DGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGD 835

Query: 1721 KGAKGLA 1727
            +G KG A
Sbjct: 836  RGEKGEA 842



 Score =  254 bits (648), Expect = 9e-67
 Identities = 165/413 (39%), Positives = 203/413 (49%), Gaps = 49/413 (11%)

Query: 1384 CCLFCKCIGGD----------GTMGDPG-----PPGKRGPPGFKGSEGYLGEEGIAGERG 1428
            C L  +C+ GD          G+ GDPG     PPG  GPPG KGS G     G+ G  G
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG---SRGLPGFPG 1072

Query: 1429 APGPVGEQGTKGCYGTKGPKGNRGLNG--QEGEVGENGIDGLNG-EQGDNGLPGRKGEKG 1485
              GP G  G  G  G +GP G  GL+     G++     D  N    G  GLPG  G KG
Sbjct: 1073 PQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG 1132

Query: 1486 DEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTP 1545
            D+G  G PG+ GT G +G  G  G PG PG    I GP G +GERG  G  G  G  G P
Sbjct: 1133 DKGVPGKPGREGTEGKKGEAGPPGLPGPPG----IAGPQGSQGERGADGEVGQKGDQGHP 1188

Query: 1546 GSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAG---VKGEKGGVGSK 1602
            G        G  G  G  G AG  GP G++GS G +GP GP+G +G   + GE+G  G  
Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248

Query: 1603 GPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRG------LQGNDGSPGY- 1655
            G  GPPG  G+AG  G  G +G +G PG  G  G  G PGPRG      L G +G PG  
Sbjct: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308

Query: 1656 ---GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMG----- 1707
               G  G +G +G  G PG++G  G  G+PG  G  G KG++G+  S GLPG +G     
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368

Query: 1708 -SPGEPGPPGRKGVKGAKGLASFSTCELIQYVR-DRSP----GRHGKPECPVH 1754
              PGE G PG++GV G  G   F        ++ D+ P    G+ G P  P H
Sbjct: 1369 GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH 1421



 Score =  248 bits (634), Expect = 4e-65
 Identities = 160/397 (40%), Positives = 188/397 (47%), Gaps = 63/397 (15%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ GP G  GPPG KG EG  G  G AG  GAPG VG  G  G  G+ G  G R
Sbjct: 883  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942

Query: 1452 GLNGQEGEVGENGIDGLNG---------EQGDNGLP-----GRKGEKGDEGSQGSPGKRG 1497
            G  G++GE GE G  G  G         + G  GLP     G+ GE G  GS G PG  G
Sbjct: 943  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLG 1002

Query: 1498 T--------------------PGDRGAKGLRGDPGA---PGVD-SSIEGPTGLKGERGRQ 1533
            T                     GDRGA G+ G PG+   PG+  +   GP+G  G++G  
Sbjct: 1003 TKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSP 1062

Query: 1534 GRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI---------------------PGPD 1572
            G RG PG PG  G   +  A G  G  GP G  G+                     PGP 
Sbjct: 1063 GSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP 1122

Query: 1573 GLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDL 1632
            GL G  G KG +G  G+ G +G +G  G  GP G PGP G AG QG  G +G  GE G  
Sbjct: 1123 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 1182

Query: 1633 GEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGET 1688
            G++G  G PG  G  GN G PG     G+ G  G +G  G  G  GP+G  G PG PGE 
Sbjct: 1183 GDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEE 1242

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G +G  GK    G PG+ G PG PGP G +G  G KG
Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 1279



 Score =  240 bits (612), Expect = 1e-62
 Identities = 160/412 (38%), Positives = 192/412 (46%), Gaps = 63/412 (15%)

Query: 1392 GGDGTMGDPGPPGKRGP------------------PGFKGSEGYLGEEGIAGERGAPGPV 1433
            G  G  G+ G PGK GP                  PG KG  G  GE+G+ G+ G  G +
Sbjct: 729  GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEI 788

Query: 1434 GEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSP 1493
            GEQG  G  G KG  G  G  G  G  GE G  G  GE G  GL G +GEKG+ G  G P
Sbjct: 789  GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPP 848

Query: 1494 GKRGT----------PGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPG 1543
            G  GT          PG++G KG +GDPG P       G  GL+G  G  G +G  GPPG
Sbjct: 849  GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP-------GEPGLQGRPGELGPQGPTGPPG 901

Query: 1544 TPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
              G      A G  G+ G  G  G PGP G  GS+G  G +G  G+ G +GEKG  G +G
Sbjct: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961

Query: 1604 PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRG------------------ 1645
              GP GP G+ G  G  G  G KG+ G+ G +G+ G PGP G                  
Sbjct: 962  SPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGG 1020

Query: 1646 --LQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGL 1702
              ++G+ G+PG  GS G +G  G  G  G  GP G  GD G PG  GL G  G    AG 
Sbjct: 1021 QCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079

Query: 1703 PGEMGSPGEPGPPGRKGVKGAKGLASFSTCELI--QYVRDRSPGRHGKPECP 1752
             G  G+PGE GPPG+ G+     L S     L+      D  PG  G P  P
Sbjct: 1080 DGAPGNPGERGPPGKPGL---SSLLSPGDINLLAKDVCNDCPPGPPGLPGLP 1128



 Score =  239 bits (609), Expect = 3e-62
 Identities = 165/415 (39%), Positives = 191/415 (46%), Gaps = 60/415 (14%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG  GPP   G+ G  G +GIA   GA GP G QG+ G  G  GP+G 
Sbjct: 1179 VGQKGDQGHPGVPGFMGPP---GNPGPPGADGIA---GAAGPPGIQGSPGKEGPPGPQGP 1232

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGD 1510
             GL G  GE G+ G DG  G  G+ G  G  G  G EG++G PG +G  GD GA G RG+
Sbjct: 1233 SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGE 1292

Query: 1511 PGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPG 1570
             GA G+    EG  G  G+ G  G +G  GP G PG   K  + G  G  GP GT G  G
Sbjct: 1293 SGAMGLPGQ-EGLPGKDGDTGPTGPQGPQGPRGPPG---KNGSPGSPGEPGPSGTPGQKG 1348

Query: 1571 PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPG 1630
              G  GS GL G  GPRG  G  GEKG  G +G  G PG  G  G +G  G +G+KG PG
Sbjct: 1349 SKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 1408

Query: 1631 DLGEKGAVGFPGPR---GLQGNDGSPG-YGSVGRKGAKGQEGFPGESG------------ 1674
              G+ G  G PG +   GL G  G PG  G VG  G  GQ GFPG  G            
Sbjct: 1409 GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLI 1468

Query: 1675 --------------------------PKGEIGDPGGPGETGLKGARGKMISAGLPGEMGS 1708
                                       +G  G PG PG+ GL G  G M   G PG+ G 
Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528

Query: 1709 PGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALD 1763
             G  GP G KG +GAKG        L         G  G P  P  P E  +A D
Sbjct: 1529 EGPSGPIGPKGERGAKGDPGAPGVGL--------RGEMGPPGIPGQPGEPGYAKD 1575



 Score =  238 bits (608), Expect = 4e-62
 Identities = 158/413 (38%), Positives = 191/413 (46%), Gaps = 75/413 (18%)

Query: 1398 GDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQE 1457
            G+ GP G++G PG  G  G  G  G  G +G  GP G +G +G +G  G  GN G  G  
Sbjct: 865  GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924

Query: 1458 GEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS---QGSPGKRGTPGDRGAKGLRGDPGA- 1513
            G  G +G  G  G  G  G PG+ GE+G++G+   +GSPG  G  GD GA GL G PG  
Sbjct: 925  GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 984

Query: 1514 ----PGVDSS--IEGPTGLKGERGR--------------QGRRGWPGPPGTPGSRRKTAA 1553
                PG+  S  + GP G K   G+              +G RG PG PG+PGSR     
Sbjct: 985  KDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI 1044

Query: 1554 HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQG------- 1606
                G  GP G +G PG  G  GS GL G  GP+G AG  G  G  G +GP G       
Sbjct: 1045 ----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100

Query: 1607 -----------------PPGPGGEAGNQGRLGSQGNKGEPG------DLGEKGAVGFPGP 1643
                             PPGP G  G  G  G +G  G+PG        GE G  G PGP
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 1644 RGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGL 1702
             G+ G  GS G  G+ G  G KG +G PG  G  G  G+PG PG  G+ GA      AG 
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA------AGP 1214

Query: 1703 PGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
            PG  GSPG+ GPPG +G  G  G+             +   GR GKP  P  P
Sbjct: 1215 PGIQGSPGKEGPPGPQGPSGLPGIPG----------EEGKEGRDGKPGPPGEP 1257



 Score =  231 bits (588), Expect = 8e-60
 Identities = 146/376 (38%), Positives = 171/376 (45%), Gaps = 58/376 (15%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGP G RGPPGFKG  G  G  G  GE GA G  G++G  G  G  GP G +
Sbjct: 1258 GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ 1317

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPG---KRGTPGDRGAKGLR 1508
            G  G  G  G+NG  G  GE G +G PG+KG KG+ GS G PG    RG PG+ G KG+ 
Sbjct: 1318 GPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVP 1377

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G  G PG      G  G KGERG  G +G  GPPG  G        G +GHTG  G  G+
Sbjct: 1378 GKEGVPGKP----GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGV----------------------------- 1599
            PG +G    +G  GP G  G  G++GE   +                             
Sbjct: 1434 PGENG---PVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490

Query: 1600 ---GSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYG 1656
                S+G  GPPGP G+ G  GR G  G  G PG  G +G  G  GP+G +G  G PG  
Sbjct: 1491 YMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAP 1550

Query: 1657 SVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPG 1716
             VG +G  G  G PG+ G  G   D       GL G         +PG  G  G  G PG
Sbjct: 1551 GVGLRGEMGPPGIPGQPGEPGYAKD-------GLPG---------IPGPQGETGPAGHPG 1594

Query: 1717 RKGVKGAKGLASFSTC 1732
              G  G  G    S C
Sbjct: 1595 LPGPPGPPGQCDPSQC 1610



 Score =  133 bits (335), Expect = 2e-30
 Identities = 83/255 (32%), Positives = 143/255 (56%), Gaps = 10/255 (3%)

Query: 616 CKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQ 675
           CK +  D++FL+D+S S+G E+F K++ ++ NLV   ++GPDR ++GVV++SD     F+
Sbjct: 32  CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFE 91

Query: 676 LNRFMSQSDISNAIDQMAHIGQTTLTGSALSFV-SQYFSPTKGARPNIRKF---LILITD 731
           L  F SQ ++  A  ++A+ G  T TG AL ++ ++ FSP  G RP  R +    IL+TD
Sbjct: 92  LGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTD 151

Query: 732 GEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEM--VFYVENFDILQRIED 789
           G +QD+V + A    + G+ I++VGV  +   +LEEI+  P+   VF+V +F+ + +I  
Sbjct: 152 GRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRG 211

Query: 790 DLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMI-GLVKKADVG--KNQV 846
            L   +C     C  + V    F   + G+ +   +++M  F +  ++ K + G   + V
Sbjct: 212 KLRRRLCE-NVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYV 270

Query: 847 RFGALKYADDPEVLF 861
           R G+       E +F
Sbjct: 271 RMGSFPVVQSTEDVF 285



 Score =  113 bits (282), Expect = 2e-24
 Identities = 64/194 (32%), Positives = 108/194 (55%), Gaps = 4/194 (2%)

Query: 987  CNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSD 1046
            C + +  C+    DLVFL+D S+S+   DF+K+++++A++V  F+V  +R R+G  ++SD
Sbjct: 25   CQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSD 84

Query: 1047 TYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREV-EHYFRPDMGSR-INTGTPQ 1104
                 F LG F  ++E+      +    GNT+ G ALR +    F P  G R  +    Q
Sbjct: 85   RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144

Query: 1105 VLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVH--NFD 1162
            V ++LTDG+SQD V  AA A    GI I++VG+G+   ++L +I    +     H  +F+
Sbjct: 145  VAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFN 204

Query: 1163 ELKKVNKRIVRNIC 1176
             + K+  ++ R +C
Sbjct: 205  AIDKIRGKLRRRLC 218



 Score =  110 bits (274), Expect = 2e-23
 Identities = 69/255 (27%), Positives = 127/255 (49%), Gaps = 8/255 (3%)

Query: 426 KSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWD 485
           ++GC      D+  L+D S S    DF +++ +++ +V  F + P + RVG V+Y+D   
Sbjct: 29  RAGCKSVHY-DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPT 87

Query: 486 LEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLL---QKAKKQRGNKVPCHLV 542
             FE+  + +++++  A   +   GGNTNTG AL +  +         + R        +
Sbjct: 88  TAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAI 147

Query: 543 VLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEK--RVYYVHDFDALK 600
           +LT+G S+D +L+ A       IR++A+G+ EA + +L EIA E K   V++V DF+A+ 
Sbjct: 148 LLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAID 207

Query: 601 DIRNQVVQEICTEEACKEMKAD-IMFLVDSSGSIGPENFSKMKTF-MKNLVSKSQIGPDR 658
            IR ++ + +C    C  ++ +   F   + G+     F  M  F +K ++ K + G   
Sbjct: 208 KIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQS 267

Query: 659 VQIGVVQFSDINKEE 673
             + +  F  +   E
Sbjct: 268 SYVRMGSFPVVQSTE 282



 Score =  101 bits (252), Expect = 7e-21
 Identities = 61/146 (41%), Positives = 76/146 (52%), Gaps = 24/146 (16%)

Query: 1604 PQGPPGPGGE-------------AGNQGRLGSQGNKGEPG---DLGEKGAVGFPGPRGLQ 1647
            PQ PP PG E             AG +G +G  G  G PG   D+G  G VG PGP+G +
Sbjct: 457  PQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEK 516

Query: 1648 GNDGSP--GYGSVGRKGAKGQEGFPGESGPK------GEIGDPGGPGETGLKGARGKMIS 1699
            G+ G    G G  G KG+ G  G PG  G K      GE+G+PG PGE G++G +G    
Sbjct: 517  GDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGL 576

Query: 1700 AGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G PG +G+PG  G  G KG +G KG
Sbjct: 577  PGPPGRVGAPGLQGERGEKGTRGEKG 602



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 58/196 (29%), Positives = 97/196 (49%), Gaps = 5/196 (2%)

Query: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
           D+VFLLD S +  +E+F+ ++ ++   V   ++  +  RVG+V YS+       L +  +
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDN 347
           + EV    + L+   G   TG A++ +    FS   G R +++   Q+A+L+T   S+D 
Sbjct: 98  QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157

Query: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
           V  AA    R G+ IF +G+  A   +LE+IAS P   +V  +  F  +         KL
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAI----DKIRGKL 213

Query: 408 RNQITHTVSVFSERTE 423
           R ++   V   S R E
Sbjct: 214 RRRLCENVLCPSVRVE 229



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 64/204 (31%), Positives = 102/204 (50%), Gaps = 15/204 (7%)

Query: 794 GICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKY 853
           G  + R  CK +   D+VF++D+S S+  +++  ++ ++  LV   +VG ++ R G ++Y
Sbjct: 24  GCQAQRAGCKSVHY-DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRY 82

Query: 854 ADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEAL------GFSDHMFTEARGSRL 907
           +D P   F L  FG++ EV +  +     GG+T T +AL       FS H    A G   
Sbjct: 83  SDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPH----AGGRPR 138

Query: 908 NKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVEL--LAMAGSSDK 965
           ++   QV I++TDG S D   L+A A A R  GI + AVG+  A   EL  +A    S  
Sbjct: 139 DRAYKQVAILLTDGRSQDL-VLDAAAAAHR-AGIRIFAVGVGEALKEELEEIASEPKSAH 196

Query: 966 YFFVETFGGLKGIFSDVTASVCNS 989
            F V  F  +  I   +   +C +
Sbjct: 197 VFHVSDFNAIDKIRGKLRRRLCEN 220



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 44/154 (28%), Positives = 84/154 (54%), Gaps = 2/154 (1%)

Query: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
           D+VFL+D+S  +G + F  V+ ++  ++ +  +  D+ RV + +YSD+  + F L  F G
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLF-G 96

Query: 87  RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDK-KQFPPILVVLASSESED 145
               +    +   + GG+   G AL+      FS  A GR + + +  + ++L    S+D
Sbjct: 97  SQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179
            V +A+ A  + G++I +VGV +A +E L+ +A+
Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIAS 190



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGF-----KGSEGYLGEEGIAGERGAPGPVGEQG 1437
            +G  G MG PG PG+ G PG+      G  G  GE G AG  G PGP G  G
Sbjct: 1552 VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603



 Score = 40.8 bits (94), Expect = 0.015
 Identities = 46/205 (22%), Positives = 83/205 (40%), Gaps = 19/205 (9%)

Query: 1952 CDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVA 2011
            C   R      + D  FLLD S ++G  +FE +R ++  L+D FE+ P+        RV 
Sbjct: 25   CQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPD------RTRVG 78

Query: 2012 LLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDN 2071
            ++ ++     P T        F L  + S+  +K      +    G+   G AL++    
Sbjct: 79   VVRYSD---RPTT-------AFELGLFGSQEEVKAAARR-LAYHGGNTNTGDALRYITAR 127

Query: 2072 VFLSTPNLR-RNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELE 2130
             F      R R++    ++   T     +++   +  A   G  +F   +G    + ELE
Sbjct: 128  SFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKE-ELE 186

Query: 2131 DLASHPLDHHLVQLGRIHKPDHSYG 2155
            ++AS P   H+  +   +  D   G
Sbjct: 187  EIASEPKSAHVFHVSDFNAIDKIRG 211



 Score = 33.5 bits (75), Expect = 2.4
 Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 10/144 (6%)

Query: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816
            +LVF LD S  V +++FE++++ +A LV   +V  +   VG    ++ Y+          
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVG----VVRYSDRPTTAFELG 93

Query: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHT----RKIATFFSS 1872
                + ++      + Y     +   G A+R+I+   F     G       +++A   + 
Sbjct: 94   LFGSQEEVKAAARRLAYH--GGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTD 151

Query: 1873 GQSADAHSITTAAMEFGALEIIPV 1896
            G+S D      AA     + I  V
Sbjct: 152  GRSQDLVLDAAAAAHRAGIRIFAV 175


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  265 bits (678), Expect = 3e-70
 Identities = 152/342 (44%), Positives = 184/342 (53%), Gaps = 11/342 (3%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG +G  GF G  G +GE+G +G+ G PG  GE+G  G  G +G  G 
Sbjct: 787  LGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
             G  G +G+VG++G  G+ GE+G  GL   PG  G KG  G QG  G+ G PG RG  G 
Sbjct: 847  TGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGF 906

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAG 1567
            +G  G PG  + + GP G  GE G  G RG PGPPG PG +      G  G  G +G  G
Sbjct: 907  QGQTGPPG-PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQ---GLPGLEGREGAKGELG 962

Query: 1568 IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKG 1627
             PGP G EG  GL+G  GP+G  G  G  G  G KGP GP G  G  G +G LG  G  G
Sbjct: 963  PPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIG 1022

Query: 1628 EPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPG 1686
             PG  G +G VG  G +G +G  G PG  G  G  G  G  G PG +GP GE GD G  G
Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082

Query: 1687 ETGLKGARGKMISAGLPGE---MGSPGEPGPPGRKGVKGAKG 1725
              G KG++G    AG PG+    G  G PGPPG  G +G +G
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG 1124



 Score =  262 bits (669), Expect = 3e-69
 Identities = 167/388 (43%), Positives = 197/388 (50%), Gaps = 57/388 (14%)

Query: 1395 GTMGDPGPPGKRGPPGFKGSEGYLGE---EGIAGERGAPGPVGEQGTKGC---YGTKGPK 1448
            GT G+ GPPG  G PG  GS+G LG    EG  GE+GA GP G  G  G     G KG  
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 1449 GNRGLNGQEGEVGENGID------GLNGEQGDNGLPGRKGEKGDE---------GSQGSP 1493
            GNRGL G++GE GE+G        GL G+QG  G PG +GE G E         G +G P
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 1494 GKRGTPGDRGAKGLRGDPGAPGVDSSIE-----GPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G  G  G  GL G PG PG   SI      GP G KG+ G+ G+ G  G  G PGSR
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838

Query: 1549 RKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP 1608
             +    G  G  GP+G  G  G  G+ G  GL G QGP G  G KG  G  G  G  G P
Sbjct: 839  GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHP 898

Query: 1609 GPGGEAGNQGR---------LGSQGNKGEPGDLGEKGAVGFPGP------RGLQGNDGSP 1653
            G  GE G QG+         LG QG  GE G LGE+G  G PGP       GL+G +G+ 
Sbjct: 899  GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 1654 GY----GSVGRKGAKGQEGF------PGESGPKGEIGDPGGPGETGLKGA---RGKMISA 1700
            G     G +G++G  G  GF      PG+ GP G  GD G PG  G  G+   RG +  A
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018

Query: 1701 ---GLPGEMGSPGEPGPPGRKGVKGAKG 1725
               GLPG+ GS G  GP G+KG +G +G
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERG 1046



 Score =  260 bits (665), Expect = 9e-69
 Identities = 159/384 (41%), Positives = 190/384 (49%), Gaps = 51/384 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGP------------PGFKGSEGYL---------GEEGIAGERGA 1429
            +G  G  G  G PG  GP            PG KG  G           GE+G  G  G 
Sbjct: 529  MGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP 588

Query: 1430 PGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS 1489
            PGP G+ G  G  G  GP+G+ G  G+ G  G +G  G  G  G  G PG  G++G+ GS
Sbjct: 589  PGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648

Query: 1490 QGSPGKR---GTPGDRGAKGLRGDPGAPGVDSSI-----EGPTGLKGERGRQGRRGWPGP 1541
            QG PG +   GTPG++G  G  G PG PG D  +     EGPT   GE+G QG  G  GP
Sbjct: 649  QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT---GEKGAQGPPGSAGP 705

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQ------GPRGEAGVKGE 1595
            PG PG R      G RG  G +G  G  G  G +G +GLKG Q      GPRGE G +G 
Sbjct: 706  PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP 765

Query: 1596 KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGP------RGLQGN 1649
            KG  G  G +GPP   G AG +G+LG  G  G PG  G KG++GFPGP      +G  G 
Sbjct: 766  KGQAGQAGEEGPP---GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGK 822

Query: 1650 DGSPGY----GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGE 1705
             G PG     G  G +G +GQ G  G+ GPKG++G  G PG  G KG  G     G PG 
Sbjct: 823  TGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGP 882

Query: 1706 MGSPGEPGPPGRKGVKGAKGLASF 1729
             G PG  G  GR G  G +G   F
Sbjct: 883  KGPPGHQGKDGRPGHPGQRGELGF 906



 Score =  260 bits (665), Expect = 9e-69
 Identities = 157/371 (42%), Positives = 187/371 (50%), Gaps = 41/371 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEG------YLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G  G PG PG +GPPG +G +G        GE G  G+ G PGP G  G +G  G  
Sbjct: 869  GLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEV 928

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQG---DNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            GP G RG  G  G  GE G+ GL G +G   + G PG  G++G  G +G PG +G PGD 
Sbjct: 929  GPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDP 988

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G  GL+GD G PG      G  G  GERG  G  G  G PG  GS       G++G  G 
Sbjct: 989  GPTGLKGDKGPPGP----VGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGE 1044

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGS--------------------- 1601
            +G  G  G DG+ G LG  GP G  G +G +G+KG VG+                     
Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104

Query: 1602 KGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGR 1660
            +GP G PGP G  G QGR G  G  G+ GD G +G VG  GP GLQG  G PG  G VG 
Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 1661 KGAKGQEGFPGESGPKGEIGD------PGGPGETGLKGARGKMISAGLPGEMGSPGEPGP 1714
             G+ G  G PG  GP+G  G       PGG G+ G  G +G+   AG PG  G+PG PGP
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224

Query: 1715 PGRKGVKGAKG 1725
             G  G KG  G
Sbjct: 1225 KGDIGEKGDSG 1235



 Score =  259 bits (663), Expect = 2e-68
 Identities = 154/365 (42%), Positives = 185/365 (50%), Gaps = 38/365 (10%)

Query: 1392 GGDGTMGDPGP------PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G+ G PGP      PG++GPPG  G  G  G +G  G  G  GP GE+G +G  G+ 
Sbjct: 644  GNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSA 703

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE---KGDEGSQGSPGKRGTPGDR 1502
            GP G  G  G +G  G  G+ G  GE+G++G PG KG+   KGD+G  G+PG RG  G  
Sbjct: 704  GPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSR-------------- 1548
            G KG  G  G        EGP G  GE+G+ G  G PG PG PG +              
Sbjct: 764  GPKGQAGQAGE-------EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816

Query: 1549 ----RKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
                 KT   G  G  GP G+ G  G  G  G  G KG  G  G  G+ GEKG  G +GP
Sbjct: 817  KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGP 876

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGA 1663
             G PGP G  G+QG+ G  G+ G+ G+LG +G  G PGP G+ G  G  G  G +G +G 
Sbjct: 877  PGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP 936

Query: 1664 KGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGL---PGEMGSPGEPGPPGRKGV 1720
             G  G PGE G  G  G  G  GE G  G  GK   AGL   PG  G PG+PGP G KG 
Sbjct: 937  PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996

Query: 1721 KGAKG 1725
            KG  G
Sbjct: 997  KGPPG 1001



 Score =  259 bits (662), Expect = 2e-68
 Identities = 154/360 (42%), Positives = 185/360 (51%), Gaps = 32/360 (8%)

Query: 1391 IGGDGTMGDPGPPGKR---GPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP 1447
            +G  G  G PG PG R   GP G KG  G  GEEG  G  G  G +G  G  G  G  GP
Sbjct: 742  VGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGP 801

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGE---QGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGA 1504
            KG+ G  G  G +GE G  G  G+   +G+ G PG +GE+G  G+ G PG +G  G  GA
Sbjct: 802  KGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGA 861

Query: 1505 KGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQG 1564
             G+ G+ G PG    ++GP G  G +G  G +G  G PG PG R +    G +G TGP G
Sbjct: 862  PGIPGEKGLPG----LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL---GFQGQTGPPG 914

Query: 1565 TAGIPGPDGLEGSL------GLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
             AG+ GP G  G +      G  GP GP GE G+ G +G  G+KG  GPPGP G+ G  G
Sbjct: 915  PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-------YGSVGRKGAKGQEGFPG 1671
              G  G KG PGD G  G  G  GP G  G +GSPG        G +G  G  G EG  G
Sbjct: 975  LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034

Query: 1672 ESGPKGEIGDPGGPGETGLKGARGKMISAGLP------GEMGSPGEPGPPGRKGVKGAKG 1725
             +G KG  G+ G PG TG  G  G +   G P      GE G  G+ G PG KG KG KG
Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG 1094



 Score =  257 bits (657), Expect = 8e-68
 Identities = 151/349 (43%), Positives = 174/349 (49%), Gaps = 15/349 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G DG  G  GPPG  G  G  G  G++G  G  G +G PGP GE+G  G  G+ GP G  
Sbjct: 1115 GADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAP 1174

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G +G  G  G  GL G  G  G  G KGE+GD G  G PG  G PG +G  G +GD 
Sbjct: 1175 GPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS 1234

Query: 1512 GAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
            G  G       +GP G  G +G  G  G PG  G PG    +   G  G  G  G  G P
Sbjct: 1235 GPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294

Query: 1570 GPDGLEGSLGLKGPQGPRGEAGV------KGEKGGVGSKGPQGPPG---PGGEAGNQGRL 1620
            GP G  G  G  GP G RG +G       +GEKG  G  GP GPPG   P G  G  GR+
Sbjct: 1295 GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRV 1354

Query: 1621 GSQGNKGEPGDLGEKGAVGFPG---PRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPK 1676
            G +G +G PG +GE G +G PG   P G  G  G PG  G  G KG KG  G  G  GP 
Sbjct: 1355 GPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPP 1414

Query: 1677 GEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            GE G+ G  G  G++G  G     G PG +GS G PGPPG  G  G KG
Sbjct: 1415 GEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463



 Score =  253 bits (645), Expect = 2e-66
 Identities = 154/359 (42%), Positives = 185/359 (51%), Gaps = 35/359 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEG---IAGERGAPGPVGEQGTKGCYGTK--- 1445
            G  G  G PGP G  G PG KG EG  G +G   + G  G PG VG+ G  G  G +   
Sbjct: 482  GPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLP 541

Query: 1446 ---GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
               GPKG+RG +G  G  GE G  G  G  G  G PG  GE+G EG  G  G+ G PG R
Sbjct: 542  GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR 601

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G  G RG PG  G      G TG+ G  G +G  G PG PG PG +     HG +G  GP
Sbjct: 602  GLLGPRGSPGPTG----RPGVTGIDGAPGAKGNVGPPGEPGPPGQQ---GNHGSQGLPGP 654

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPP---GPGGEAGNQGR 1619
            QG  G PG  G  G+ G+ G  G  G  G  G +G  G KG QGPP   GP G  G +G 
Sbjct: 655  QGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV 714

Query: 1620 LGSQGNKGEPGDLGEKGAVGFPGPR---GLQGNDGSPG----------YGSVGRKGAKGQ 1666
             G+ GN+G  G+ GEKG  GFPG +   GL+G+ G PG           G  G+ G  G+
Sbjct: 715  KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774

Query: 1667 EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            EG PG +G KG++G PG PG  G  G +G   S G PG +G  GE G  G+ G  G +G
Sbjct: 775  EGPPGSAGEKGKLGVPGLPGYPGRPGPKG---SIGFPGPLGPIGEKGKSGKTGQPGLEG 830



 Score =  252 bits (644), Expect = 3e-66
 Identities = 150/346 (43%), Positives = 178/346 (51%), Gaps = 21/346 (6%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+ G  G  G PG KGS+G  G+ G  G+ G  GP G  G  G  G +G +G  
Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL GQ+G+ G  G  G+ G  G  GLPG  GEKG+ G  GS G  G PG RG +G  G  
Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG+   + G  G  GE+G +G  G PGPPG PG        G +G +GP G AG PG 
Sbjct: 1187 GTPGLPGGV-GQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK 1245

Query: 1572 ------DGLEGSLG---LKGPQGPRGEAGVKGEKGGVGSKGPQGP---PGPGGEAGNQGR 1619
                  DG +GS+G   L G  GP G+ GV G  G  G KG  G    PGP G +G  G 
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305

Query: 1620 LGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEI 1679
             G  G +G  G +G +G  G  G +G  G DG PG     R G  G  G PG  GP+G  
Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPG-----RTGPMGARGPPGRVGPEGLR 1360

Query: 1680 GDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G PG  GE GL GA G+M   G PG +G  G PG  G  G KG KG
Sbjct: 1361 GIPGPVGEPGLLGAPGQM---GPPGPLGPSGLPGLKGDTGPKGEKG 1403



 Score =  252 bits (644), Expect = 3e-66
 Identities = 158/362 (43%), Positives = 184/362 (50%), Gaps = 39/362 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G +G  GPPG +G PG  G +G +G+ G  G  GAPGP G QG  G  GT G  G  
Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGV 1195

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKG---EKGDEGSQGS---PGKRGTPGDRGAK 1505
            G  G  GE GE G  G  G  G  G+PG KG   EKGD G  G+   PGK+G PG+ GAK
Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAK 1255

Query: 1506 ------GLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGT---------PGSRRK 1550
                  GL GD G PG D  + G  G  GE+G  G  G PGPPG          PG R  
Sbjct: 1256 GSVGPTGLPGDLGPPG-DPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGP 1314

Query: 1551 TAAHGRRGHTGPQGTAGIPGPD---------GLEGSLGLKGPQGPRGEAGVKGEKGGVGS 1601
            +   GR G  G +G  G PGPD         G  G  G  GP+G RG  G  GE G +G+
Sbjct: 1315 SGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGA 1374

Query: 1602 KGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRK 1661
             G  GPPGP G +G  G  G  G KGE G +G  G +G PG  G +G+ G PG      +
Sbjct: 1375 PGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV-----Q 1429

Query: 1662 GAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVK 1721
            G  G +G PG  GP G +G PG PG  G  G +G   S G PG MG  G+ GP G  G  
Sbjct: 1430 GPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG---SKGSPGSMGPRGDTGPAGPPGPP 1486

Query: 1722 GA 1723
            GA
Sbjct: 1487 GA 1488



 Score =  251 bits (642), Expect = 4e-66
 Identities = 152/363 (41%), Positives = 180/363 (49%), Gaps = 29/363 (7%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G  G  G+RGPPG  G +G  G  G  G  GA GP GE+G KG  G  G KG++
Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSK 1090

Query: 1452 GLNGQEGEVGENGI---------DGLNGEQGDNGLPGRKGEKGDEGSQG------SPGKR 1496
            G  G  G  G+ GI          G +G QG  G PG  G+KGD+G +G       PG +
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQ 1150

Query: 1497 GTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR 1556
            G PG  G KG  GD G+ G   +  GP G +G  G +G  G PG  G PG+  +    G 
Sbjct: 1151 GLPGPPGEKGEVGDVGSMGPHGA-PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGD 1209

Query: 1557 RGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGN 1616
             G  GP G  GIPGP G  G  G  GP G  G  G KG  G  G+KG  GP G  G+ G 
Sbjct: 1210 AGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGP 1269

Query: 1617 QGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----------YGSVGRKGAKGQ 1666
             G  G  G  G PG+ G+ G VG PGP G  G  G+PG           G  GR+G KG 
Sbjct: 1270 PGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGA 1329

Query: 1667 EGFPGESGPKGEIGDPGG---PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGA 1723
            +G PG  GP G  G  G    PG  G +G RG     G PG +G+PG+ GPPG  G  G 
Sbjct: 1330 KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGL 1389

Query: 1724 KGL 1726
             GL
Sbjct: 1390 PGL 1392



 Score =  249 bits (635), Expect = 3e-65
 Identities = 148/352 (42%), Positives = 181/352 (51%), Gaps = 22/352 (6%)

Query: 1391 IGGDGTMGDPGPPGKRGP---PGFKGSEGYL---GEEGIAGERGAPGPVGEQGTKGCYGT 1444
            +G +G+ G+ GP G  G    PG  GSEG +   G++G  GERG PGP G+ G  G  G 
Sbjct: 1003 VGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGP 1062

Query: 1445 KGPKGNRGLNGQE---GEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGD 1501
             GP G  G +G+E   G+VG  G  G  G++GD G PG+ G +G  G  G PG  G  G 
Sbjct: 1063 LGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGR 1122

Query: 1502 RGAKGLRGDPGAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            RG  GL G  G  GV     + GP GL+G  G  G +G  G  G+ G        G +G 
Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182

Query: 1560 TGPQGTAGIPGPDGLEGSLGLKGPQ------GPRGEAGVKGEKGGVGSKGPQGPPGPGGE 1613
            TG +GT G+PG  G  G++G KG +      GP G  G+ G KG +G KG  GP G  G 
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGP 1242

Query: 1614 AGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGES 1673
             G +G  G  G KG  G  G  G +G PG  G+ G DGSP     G KG  G  G PG  
Sbjct: 1243 PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP-----GEKGDPGDVGGPGPP 1297

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G  GE G PG PG+ G  G  G+    G  G  G PG  GPPGR G  GA+G
Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349



 Score =  241 bits (614), Expect = 8e-63
 Identities = 156/370 (42%), Positives = 178/370 (48%), Gaps = 41/370 (11%)

Query: 1395 GTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG-----------------PVGEQG 1437
            G  G PGPPG  G PG  G  G  G  GI G RG PG                 PV  Q 
Sbjct: 404  GPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQ 463

Query: 1438 TKGC-------YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQ 1490
             +            KGP G  GL G+ G VG  G  GL GE+G  G  G +G +G  G  
Sbjct: 464  AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523

Query: 1491 GSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRK 1550
            G  GK G PG  GA+GL GD G  G D   +G  GL GE+G++G  G  G PG PG   +
Sbjct: 524  GRVGKMGRPGADGARGLPGDTGPKG-DRGFDGLPGLPGEKGQRGDFGHVGQPGPPG---E 579

Query: 1551 TAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGP 1610
                G  G  GP G AG PGP GL G  G  GP G  G  G+ G  G  G+ GP G PGP
Sbjct: 580  DGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGP 639

Query: 1611 GGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----GSVGRKGAK-- 1664
             G+ GN G  G  G +G  G  GEKG  G PG  GL G+DG  G+    G  G KGA+  
Sbjct: 640  PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP 699

Query: 1665 ----GQEGFPGESGPKGEIGDPGGPGETGLKGA---RGKMISAGLPGEMGSPGEPGPPGR 1717
                G  G+PG  G KG  G+ G  GE G KG     G     GL G+ G PG PGP G 
Sbjct: 700  PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759

Query: 1718 KGVKGAKGLA 1727
             G +G KG A
Sbjct: 760  DGPEGPKGQA 769



 Score =  169 bits (427), Expect = 4e-41
 Identities = 113/320 (35%), Positives = 137/320 (42%), Gaps = 82/320 (25%)

Query: 1480 RKGEKGDEGSQGSPGKRGTPGDR---------GAKGLRGDPGAPGVDSSIEGPTGLKGER 1530
            R+ E+GD+ + G   +      R         G KG +G+P         EGP G  G +
Sbjct: 341  REDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQ 400

Query: 1531 GRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG-------------- 1576
            G  G  G PGPPG PG           G  GP G  GIPG DG+ G              
Sbjct: 401  GVVGPSGPPGPPGFPGD---------PGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAG 451

Query: 1577 ----------------------SLGLKGPQGP------------RGEAGVKGEKGGVGSK 1602
                                   L +KGP GP             G  G+KGE+G  G +
Sbjct: 452  GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ 511

Query: 1603 GP---QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSV 1658
            GP   QGP GP G  G  GR G+ G +G PGD G KG  GF G  GL G  G  G +G V
Sbjct: 512  GPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHV 571

Query: 1659 GRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLP------------GEM 1706
            G+ G  G++G  G  GP G  G  G PG  GL G RG     G P            G +
Sbjct: 572  GQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNV 631

Query: 1707 GSPGEPGPPGRKGVKGAKGL 1726
            G PGEPGPPG++G  G++GL
Sbjct: 632  GPPGEPGPPGQQGNHGSQGL 651



 Score =  103 bits (258), Expect = 1e-21
 Identities = 63/150 (42%), Positives = 72/150 (48%), Gaps = 27/150 (18%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAG---ERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G MG  GPPG+ GP G +G  G +GE G+ G   + G PGP+G  G  G  G  GPK
Sbjct: 1340 GRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPK 1399

Query: 1449 GNRG------LNGQEGEVGENGIDGLNGEQGDNGL------------------PGRKGEK 1484
            G +G      L G  GE GE G  GL G QG  G                   PG  G  
Sbjct: 1400 GEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL 1459

Query: 1485 GDEGSQGSPGKRGTPGDRGAKGLRGDPGAP 1514
            G +GS+GSPG  G  GD G  G  G PGAP
Sbjct: 1460 GQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  102 bits (255), Expect = 3e-21
 Identities = 68/167 (40%), Positives = 76/167 (45%), Gaps = 29/167 (17%)

Query: 1391 IGGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP 1447
            +G +G  G PGP   PG  G PG  G  G LG  G+ G +G  GP GE+G  G  G  GP
Sbjct: 1354 VGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGP 1413

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
                      GE GE G  GL G QG  G  G  G  G  GS G PG  G  G  G KG 
Sbjct: 1414 ---------PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGS 1464

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTP----GSRRK 1550
            +G PG+              G RG  G  G PGPPG P    G RR+
Sbjct: 1465 KGSPGS-------------MGPRGDTGPAGPPGPPGAPAELHGLRRR 1498



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 64/184 (34%), Positives = 68/184 (36%), Gaps = 46/184 (25%)

Query: 1588 GEAGVKGEKGGVGSKGPQ--GPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRG 1645
            GE G KGE   +  KG Q  GPPG  G  G  G  G  G  G PGD G  G  G PG  G
Sbjct: 373  GEKGAKGEPAVI-EKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPG 431

Query: 1646 LQGNDGSPGY----------------------------------------GSVGRKGAKG 1665
            + G  G PG                                         G VG  G  G
Sbjct: 432  IDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPG 491

Query: 1666 QEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G PG  G KGE G  G  G  GL+G  G     G  G+MG PG  G  G  G  G KG
Sbjct: 492  PVGLPGHPGLKGEEGAEGPQGPRGLQGPHGP---PGRVGKMGRPGADGARGLPGDTGPKG 548

Query: 1726 LASF 1729
               F
Sbjct: 549  DRGF 552


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  264 bits (675), Expect = 6e-70
 Identities = 166/388 (42%), Positives = 198/388 (51%), Gaps = 31/388 (7%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G MG PGPPG  GP G +G+ G  G  G+ G+   PGP G+ G KG  G  GP G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK---PGPHGDLGFKGIKGLLGPPGI 1135

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS-QGSPGKRGTPGDRGAKGLRG 1509
            RG  G  G  G  G  G+ G+QG +G+PG  GEKG+ G  +  PG RG PG +GAKG RG
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 1510 DPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
             PG PG+    +G  G  G RG  G  G+PGPPG PG+       G RG  G +G+ G P
Sbjct: 1196 APGFPGLPGR-KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSRGSPGAP 1253

Query: 1570 GPDGL-----------EGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
            GP G            +GS+G  GP+GP G AG  G  G +G+ G  G PGP G+ G QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              G +G KG PG LG  G  G  GP+G  G  G PG    +   G+ G  G PGE G +G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1678 EIGDPGGPGETGLKGARGKMISAGLPG---------EMGSPGEPGPPGRKGVKGAKGLAS 1728
            E G PG PG  G  G RGK    G PG           GS GEPGP G  G+ G KG   
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433

Query: 1729 FSTCELIQYVRDRSPGRHGK----PECP 1752
             S        R     RH +    P CP
Sbjct: 1434 DSGSPATWTTRGFVFTRHSQTTAIPSCP 1461



 Score =  254 bits (648), Expect = 9e-67
 Identities = 180/448 (40%), Positives = 206/448 (45%), Gaps = 81/448 (18%)

Query: 1390 CIGGDGTMGDPGPPG-------KRGPPGFKGSEGYLGEEGIAGERGA------------- 1429
            C G  G  G PGPPG       ++GPPG  G  GYLG  GI G  G              
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1430 -PGPVGEQGTKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
             PGP G  G  G +G KG  G +G   L G  G  G  G+ G  G  G  G PG KGEKG
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1486 D----EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP 1541
            +    EG  G PG  G  G  G KGL G PG PGV   + GP G     G +G +G PG 
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV-KGLPGPKGELALSGEKGDQGPPGD 600

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE-KGGVG 1600
            PG+PGS       G  G+ GPQG  G+ G  G+ G+ G  G  GPRGE  V     G  G
Sbjct: 601  PGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG 659

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG--AVGFPGPRGLQGNDGSPGY--- 1655
              GP G PGP G  G  G LG  G+ G PG  GE G   +GFPGP G +G+ G PG    
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1656 -------------GSVGRKGAKGQE-----------GFPGE---SGPKGEIGDPGGPGET 1688
                         G  G  GAKG+            GFPGE   SG  GEIG PG PG  
Sbjct: 720  LGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLP 779

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGR--KGVKGAKGLASFSTCELIQYVR------- 1739
            G  G  G     G PG+ G PGE GPPGR  +G +GA+GL   +  +  Q  R       
Sbjct: 780  GTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKG 839

Query: 1740 -------DRS--PGRHGKPECPVHPTEL 1758
                   DRS  PG  G P  P H  E+
Sbjct: 840  DPGIPGLDRSGFPGETGSPGIPGHQGEM 867



 Score =  253 bits (647), Expect = 1e-66
 Identities = 162/396 (40%), Positives = 189/396 (47%), Gaps = 69/396 (17%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT+G PG  G+ G PG  G +G  GE G + E   PGP G  G  G  G  G KG  
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G +G  G +G  G  G  GLPG+ G  GD G +G  G  G PG RG  GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1512 GAPGV--------DSSIEGPTGLKGE----------------RGRQGRRGWPGPPGTPGS 1547
            G+PG            I GP G KGE                +G +G RG PG PG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1548 RRKTAAHGRRGHTGPQGTAGIP--------------GPDGLEGSLGLKGPQGPRGE--AG 1591
            +      G RG TG +G  G P              GP G  GS G  GP GP G    G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1592 VKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDG 1651
            +KG+KG +G  GP+GPPG  G+ G  GRLG+ G  G PG  G+ G  GFPG +G +GN G
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1652 SPGY----GSVGRK------------------GAKGQEGFPGESGPKGEIGDPGGPGETG 1689
              G     G +G K                  G+ G  G PGE G +GE G PG PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1690 LKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G RGK      PG+ G PG PGP G KG KG+KG
Sbjct: 1386 PCGPRGK------PGKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  250 bits (639), Expect = 1e-65
 Identities = 166/414 (40%), Positives = 195/414 (47%), Gaps = 68/414 (16%)

Query: 1392 GGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG-C 1441
            GG GT G PG  G  G          PG  G+ G  G +G  G+ G PGP GEQG  G C
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 1442 YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPG--RKGEKGDEGSQGSPGKRGTP 1499
               +GP+G +GL G  G  G+ G  G  G +GD G+PG  R G  G+ GS G PG +G  
Sbjct: 810  I--EGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1500 GDRGAKGLRGDPGA---PGVDSSIE--------GPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G +G  G+PG    PG D  I         GP G  G  G  G+RG PG PG  G R
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 1549 RKTAAHGRRGHTGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
                A G +G  G  G +      G  G  GL+G  G  G +G RG  G+ G KG  G  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 1603 GPQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGAVGFPGP---------R 1644
            GP GPPGP G+ G+ G  G         S GN G PG  G++G +GFPG           
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 1645 GLQGNDGSPGYGS---VGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAG 1701
            GLQG+ G PGY      G  G  G  G PG+ G KGE+G PG PG  G  G  G   + G
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG---APG 1104

Query: 1702 LPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
             PG  G PG+PGP G  G KG KGL                PG  G P  P  P
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLG-------------PPGIRGPPGLPGFP 1145



 Score =  247 bits (630), Expect = 1e-64
 Identities = 162/377 (42%), Positives = 190/377 (50%), Gaps = 39/377 (10%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGF---KGSEGYLGEEGIAGERGAPGP---------VG 1434
            F   IG  G  G+PG PG+RG PG    KG  G  G +G  G++G PGP          G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 1435 EQGTKGCYGTKGPKGNRGLNGQEGEVGENGID---GLNGEQGDNGLPGRKGEKGDEGSQG 1491
            E G KG  G  G KGNRG+ G  G  G  G+    G  G +GD G  G  GE G  G  G
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG-----RRGWPGPPGTPG 1546
            S G  G PG +G +G  G PG  G    + G  GL+G++G  G     R G PGP G PG
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAG-RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
                    G  G  GP G  G  GP+G     GS GL G  GP G+ G KG KG +G  G
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1604 PQGPPG-PG--GEAGNQGRLGSQGNKGEPGDLGEKGAVGF----PGPRGLQGNDGSPG-Y 1655
             +GPPG PG  G  G  G  G QG  G PG  GEKG  G     PGPRG  G  G+ G  
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 1656 GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGA--RGKMISAGLPGEMGSPGEPG 1713
            G+ G  G  G++G  G++GP+G  G  G PG  GL GA   G+  + G PG  GSPG PG
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 1714 PPGRK-----GVKGAKG 1725
            PPG       G+KG KG
Sbjct: 1255 PPGPPGSHVIGIKGDKG 1271



 Score =  244 bits (623), Expect = 7e-64
 Identities = 158/413 (38%), Positives = 195/413 (47%), Gaps = 55/413 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG +G  G  G  GY G  GI G  G  G +G  G  G  G  GP GN 
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS------------QGSPGKRGTP 1499
            G  GQ G        G+ G +G  G PG KGE+GD+G+            +G PG +G  
Sbjct: 910  GTPGQRGS------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 1500 GDRGAKGLRGDPGAPGVD--SSIEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKT 1551
            G+ G KG RG PG PG+     + GP G  G RG  G  G PG       PG+ G+    
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLK-----------GPQGPRGEAGVKGEKGGVG 1600
             + G+RG  G  G AG PG  G+ G  G K           GP GP G+ G+ G+ G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEP------GDLGEKGAVGFPGPRGLQGNDGSPG 1654
              G  GPPG  G AG +G  GS G+ G P      GDLG KG  G  GP G++G  G PG
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 1655 Y----GSVGRKGAKGQEGFPGESGPKGEI-------GDPGGPGETGLKGARGKMISAGLP 1703
            +    G +G +G +G++G PG +G KGE        G  G PG  G KG RG     GLP
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLP 1203

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRS-PGRHGKPECPVHP 1755
            G  G+ G+ GP G  G++G  G        +     +R  PG  G P  P  P
Sbjct: 1204 GRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256



 Score =  239 bits (609), Expect = 3e-62
 Identities = 165/426 (38%), Positives = 199/426 (46%), Gaps = 53/426 (12%)

Query: 1379 AERTCCCLF---CKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE 1435
            A + C C     C C   DG  G+ G  G  GPPG  G +G+ G EG+      PGP G 
Sbjct: 27   ASKGCVCKDKGQCFC---DGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQGP 77

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGS 1492
            +G  G  G  G KG RG++G  G  G  G+ G  G  G  GL   PG  G KG++G  G 
Sbjct: 78   KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL 137

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIE-------GPTGLKGERGRQGRRGWPGPPGTP 1545
            PG  G PG  GA GL+G  GAP  +  IE       G  G  G +G  G  G+PGP G P
Sbjct: 138  PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPP 197

Query: 1546 GSRRKTAAHGRRGHTGPQGTAG--IPGPDGLEGSLGLKGPQGPRG-----------EAGV 1592
            G        G  G  GP+G  G  + G  G  G  GL GP GP G              +
Sbjct: 198  GPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDL 257

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQ--GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
            KGEKG  G+ G  GPPGP G  G       G+ G+ G  G  G+ G  GFPG  G++GN 
Sbjct: 258  KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317

Query: 1651 GSPG-YGSVGRKGAKGQEGFPGESGP---------KGEIGDPGGPGETGLKGARGKMISA 1700
            G PG  G  G KG KG  G PG  GP         KG+ G PG PG  G +G +G     
Sbjct: 318  GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377

Query: 1701 GLPGEMGS--PGEPGPPGRKGVKGAKGLASFSTCELIQYVRD----RSPGRHGKPECPVH 1754
            G+PG  GS  PG  G PG  G+KG+KG       + +          SPG  G P  P  
Sbjct: 378  GVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGP 437

Query: 1755 PTELVF 1760
            P ++VF
Sbjct: 438  PGDIVF 443



 Score =  114 bits (285), Expect = 1e-24
 Identities = 74/185 (40%), Positives = 83/185 (44%), Gaps = 4/185 (2%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT GD GPPG+ G PG  G  G  G+ G  G  G  G  G  G  G  G  GP G +
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G+ G   I  L G  G  G PG  G +G+ G  G PG  G  G RG  G  G P
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG--HTGPQGTAGIP 1569
            G PG  +  +G  G KGE G  G  G PG  G  G     A    RG   T    T  IP
Sbjct: 1400 GTPG-PAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458

Query: 1570 G-PDG 1573
              P+G
Sbjct: 1459 SCPEG 1463



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 51/120 (42%), Positives = 57/120 (47%), Gaps = 9/120 (7%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQG 1437
            F   IG  G +G  GPPG RG          PG  G  G  GE G+ GE G PGP G  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1438 TKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
              G  G  G  G  G  G  GE G  G  G  G  G +GLPG KG++GD GS  +   RG
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  264 bits (675), Expect = 6e-70
 Identities = 166/388 (42%), Positives = 198/388 (51%), Gaps = 31/388 (7%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G MG PGPPG  GP G +G+ G  G  G+ G+   PGP G+ G KG  G  GP G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK---PGPHGDLGFKGIKGLLGPPGI 1135

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS-QGSPGKRGTPGDRGAKGLRG 1509
            RG  G  G  G  G  G+ G+QG +G+PG  GEKG+ G  +  PG RG PG +GAKG RG
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 1510 DPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
             PG PG+    +G  G  G RG  G  G+PGPPG PG+       G RG  G +G+ G P
Sbjct: 1196 APGFPGLPGR-KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSRGSPGAP 1253

Query: 1570 GPDGL-----------EGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
            GP G            +GS+G  GP+GP G AG  G  G +G+ G  G PGP G+ G QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              G +G KG PG LG  G  G  GP+G  G  G PG    +   G+ G  G PGE G +G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1678 EIGDPGGPGETGLKGARGKMISAGLPG---------EMGSPGEPGPPGRKGVKGAKGLAS 1728
            E G PG PG  G  G RGK    G PG           GS GEPGP G  G+ G KG   
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433

Query: 1729 FSTCELIQYVRDRSPGRHGK----PECP 1752
             S        R     RH +    P CP
Sbjct: 1434 DSGSPATWTTRGFVFTRHSQTTAIPSCP 1461



 Score =  254 bits (648), Expect = 9e-67
 Identities = 180/448 (40%), Positives = 206/448 (45%), Gaps = 81/448 (18%)

Query: 1390 CIGGDGTMGDPGPPG-------KRGPPGFKGSEGYLGEEGIAGERGA------------- 1429
            C G  G  G PGPPG       ++GPPG  G  GYLG  GI G  G              
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1430 -PGPVGEQGTKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
             PGP G  G  G +G KG  G +G   L G  G  G  G+ G  G  G  G PG KGEKG
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1486 D----EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP 1541
            +    EG  G PG  G  G  G KGL G PG PGV   + GP G     G +G +G PG 
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV-KGLPGPKGELALSGEKGDQGPPGD 600

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE-KGGVG 1600
            PG+PGS       G  G+ GPQG  G+ G  G+ G+ G  G  GPRGE  V     G  G
Sbjct: 601  PGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG 659

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG--AVGFPGPRGLQGNDGSPGY--- 1655
              GP G PGP G  G  G LG  G+ G PG  GE G   +GFPGP G +G+ G PG    
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1656 -------------GSVGRKGAKGQE-----------GFPGE---SGPKGEIGDPGGPGET 1688
                         G  G  GAKG+            GFPGE   SG  GEIG PG PG  
Sbjct: 720  LGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLP 779

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGR--KGVKGAKGLASFSTCELIQYVR------- 1739
            G  G  G     G PG+ G PGE GPPGR  +G +GA+GL   +  +  Q  R       
Sbjct: 780  GTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKG 839

Query: 1740 -------DRS--PGRHGKPECPVHPTEL 1758
                   DRS  PG  G P  P H  E+
Sbjct: 840  DPGIPGLDRSGFPGETGSPGIPGHQGEM 867



 Score =  253 bits (647), Expect = 1e-66
 Identities = 162/396 (40%), Positives = 189/396 (47%), Gaps = 69/396 (17%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT+G PG  G+ G PG  G +G  GE G + E   PGP G  G  G  G  G KG  
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G +G  G +G  G  G  GLPG+ G  GD G +G  G  G PG RG  GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1512 GAPGV--------DSSIEGPTGLKGE----------------RGRQGRRGWPGPPGTPGS 1547
            G+PG            I GP G KGE                +G +G RG PG PG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1548 RRKTAAHGRRGHTGPQGTAGIP--------------GPDGLEGSLGLKGPQGPRGE--AG 1591
            +      G RG TG +G  G P              GP G  GS G  GP GP G    G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1592 VKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDG 1651
            +KG+KG +G  GP+GPPG  G+ G  GRLG+ G  G PG  G+ G  GFPG +G +GN G
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1652 SPGY----GSVGRK------------------GAKGQEGFPGESGPKGEIGDPGGPGETG 1689
              G     G +G K                  G+ G  G PGE G +GE G PG PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1690 LKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G RGK      PG+ G PG PGP G KG KG+KG
Sbjct: 1386 PCGPRGK------PGKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  250 bits (639), Expect = 1e-65
 Identities = 166/414 (40%), Positives = 195/414 (47%), Gaps = 68/414 (16%)

Query: 1392 GGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG-C 1441
            GG GT G PG  G  G          PG  G+ G  G +G  G+ G PGP GEQG  G C
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 1442 YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPG--RKGEKGDEGSQGSPGKRGTP 1499
               +GP+G +GL G  G  G+ G  G  G +GD G+PG  R G  G+ GS G PG +G  
Sbjct: 810  I--EGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1500 GDRGAKGLRGDPGA---PGVDSSIE--------GPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G +G  G+PG    PG D  I         GP G  G  G  G+RG PG PG  G R
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 1549 RKTAAHGRRGHTGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
                A G +G  G  G +      G  G  GL+G  G  G +G RG  G+ G KG  G  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 1603 GPQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGAVGFPGP---------R 1644
            GP GPPGP G+ G+ G  G         S GN G PG  G++G +GFPG           
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 1645 GLQGNDGSPGYGS---VGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAG 1701
            GLQG+ G PGY      G  G  G  G PG+ G KGE+G PG PG  G  G  G   + G
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG---APG 1104

Query: 1702 LPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
             PG  G PG+PGP G  G KG KGL                PG  G P  P  P
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLG-------------PPGIRGPPGLPGFP 1145



 Score =  247 bits (630), Expect = 1e-64
 Identities = 162/377 (42%), Positives = 190/377 (50%), Gaps = 39/377 (10%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGF---KGSEGYLGEEGIAGERGAPGP---------VG 1434
            F   IG  G  G+PG PG+RG PG    KG  G  G +G  G++G PGP          G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 1435 EQGTKGCYGTKGPKGNRGLNGQEGEVGENGID---GLNGEQGDNGLPGRKGEKGDEGSQG 1491
            E G KG  G  G KGNRG+ G  G  G  G+    G  G +GD G  G  GE G  G  G
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG-----RRGWPGPPGTPG 1546
            S G  G PG +G +G  G PG  G    + G  GL+G++G  G     R G PGP G PG
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAG-RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
                    G  G  GP G  G  GP+G     GS GL G  GP G+ G KG KG +G  G
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1604 PQGPPG-PG--GEAGNQGRLGSQGNKGEPGDLGEKGAVGF----PGPRGLQGNDGSPG-Y 1655
             +GPPG PG  G  G  G  G QG  G PG  GEKG  G     PGPRG  G  G+ G  
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 1656 GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGA--RGKMISAGLPGEMGSPGEPG 1713
            G+ G  G  G++G  G++GP+G  G  G PG  GL GA   G+  + G PG  GSPG PG
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 1714 PPGRK-----GVKGAKG 1725
            PPG       G+KG KG
Sbjct: 1255 PPGPPGSHVIGIKGDKG 1271



 Score =  244 bits (623), Expect = 7e-64
 Identities = 158/413 (38%), Positives = 195/413 (47%), Gaps = 55/413 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG +G  G  G  GY G  GI G  G  G +G  G  G  G  GP GN 
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS------------QGSPGKRGTP 1499
            G  GQ G        G+ G +G  G PG KGE+GD+G+            +G PG +G  
Sbjct: 910  GTPGQRGS------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 1500 GDRGAKGLRGDPGAPGVD--SSIEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKT 1551
            G+ G KG RG PG PG+     + GP G  G RG  G  G PG       PG+ G+    
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLK-----------GPQGPRGEAGVKGEKGGVG 1600
             + G+RG  G  G AG PG  G+ G  G K           GP GP G+ G+ G+ G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEP------GDLGEKGAVGFPGPRGLQGNDGSPG 1654
              G  GPPG  G AG +G  GS G+ G P      GDLG KG  G  GP G++G  G PG
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 1655 Y----GSVGRKGAKGQEGFPGESGPKGEI-------GDPGGPGETGLKGARGKMISAGLP 1703
            +    G +G +G +G++G PG +G KGE        G  G PG  G KG RG     GLP
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLP 1203

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRS-PGRHGKPECPVHP 1755
            G  G+ G+ GP G  G++G  G        +     +R  PG  G P  P  P
Sbjct: 1204 GRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256



 Score =  239 bits (609), Expect = 3e-62
 Identities = 165/426 (38%), Positives = 199/426 (46%), Gaps = 53/426 (12%)

Query: 1379 AERTCCCLF---CKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE 1435
            A + C C     C C   DG  G+ G  G  GPPG  G +G+ G EG+      PGP G 
Sbjct: 27   ASKGCVCKDKGQCFC---DGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQGP 77

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGS 1492
            +G  G  G  G KG RG++G  G  G  G+ G  G  G  GL   PG  G KG++G  G 
Sbjct: 78   KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL 137

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIE-------GPTGLKGERGRQGRRGWPGPPGTP 1545
            PG  G PG  GA GL+G  GAP  +  IE       G  G  G +G  G  G+PGP G P
Sbjct: 138  PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPP 197

Query: 1546 GSRRKTAAHGRRGHTGPQGTAG--IPGPDGLEGSLGLKGPQGPRG-----------EAGV 1592
            G        G  G  GP+G  G  + G  G  G  GL GP GP G              +
Sbjct: 198  GPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDL 257

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQ--GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
            KGEKG  G+ G  GPPGP G  G       G+ G+ G  G  G+ G  GFPG  G++GN 
Sbjct: 258  KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317

Query: 1651 GSPG-YGSVGRKGAKGQEGFPGESGP---------KGEIGDPGGPGETGLKGARGKMISA 1700
            G PG  G  G KG KG  G PG  GP         KG+ G PG PG  G +G +G     
Sbjct: 318  GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377

Query: 1701 GLPGEMGS--PGEPGPPGRKGVKGAKGLASFSTCELIQYVRD----RSPGRHGKPECPVH 1754
            G+PG  GS  PG  G PG  G+KG+KG       + +          SPG  G P  P  
Sbjct: 378  GVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGP 437

Query: 1755 PTELVF 1760
            P ++VF
Sbjct: 438  PGDIVF 443



 Score =  114 bits (285), Expect = 1e-24
 Identities = 74/185 (40%), Positives = 83/185 (44%), Gaps = 4/185 (2%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT GD GPPG+ G PG  G  G  G+ G  G  G  G  G  G  G  G  GP G +
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G+ G   I  L G  G  G PG  G +G+ G  G PG  G  G RG  G  G P
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG--HTGPQGTAGIP 1569
            G PG  +  +G  G KGE G  G  G PG  G  G     A    RG   T    T  IP
Sbjct: 1400 GTPG-PAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458

Query: 1570 G-PDG 1573
              P+G
Sbjct: 1459 SCPEG 1463



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 51/120 (42%), Positives = 57/120 (47%), Gaps = 9/120 (7%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQG 1437
            F   IG  G +G  GPPG RG          PG  G  G  GE G+ GE G PGP G  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1438 TKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
              G  G  G  G  G  G  GE G  G  G  G  G +GLPG KG++GD GS  +   RG
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  264 bits (675), Expect = 6e-70
 Identities = 166/388 (42%), Positives = 198/388 (51%), Gaps = 31/388 (7%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G MG PGPPG  GP G +G+ G  G  G+ G+   PGP G+ G KG  G  GP G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK---PGPHGDLGFKGIKGLLGPPGI 1135

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS-QGSPGKRGTPGDRGAKGLRG 1509
            RG  G  G  G  G  G+ G+QG +G+PG  GEKG+ G  +  PG RG PG +GAKG RG
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 1510 DPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
             PG PG+    +G  G  G RG  G  G+PGPPG PG+       G RG  G +G+ G P
Sbjct: 1196 APGFPGLPGR-KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSRGSPGAP 1253

Query: 1570 GPDGL-----------EGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
            GP G            +GS+G  GP+GP G AG  G  G +G+ G  G PGP G+ G QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1619 RLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKG 1677
              G +G KG PG LG  G  G  GP+G  G  G PG    +   G+ G  G PGE G +G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1678 EIGDPGGPGETGLKGARGKMISAGLPG---------EMGSPGEPGPPGRKGVKGAKGLAS 1728
            E G PG PG  G  G RGK    G PG           GS GEPGP G  G+ G KG   
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433

Query: 1729 FSTCELIQYVRDRSPGRHGK----PECP 1752
             S        R     RH +    P CP
Sbjct: 1434 DSGSPATWTTRGFVFTRHSQTTAIPSCP 1461



 Score =  254 bits (648), Expect = 9e-67
 Identities = 180/448 (40%), Positives = 206/448 (45%), Gaps = 81/448 (18%)

Query: 1390 CIGGDGTMGDPGPPG-------KRGPPGFKGSEGYLGEEGIAGERGA------------- 1429
            C G  G  G PGPPG       ++GPPG  G  GYLG  GI G  G              
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1430 -PGPVGEQGTKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
             PGP G  G  G +G KG  G +G   L G  G  G  G+ G  G  G  G PG KGEKG
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1486 D----EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP 1541
            +    EG  G PG  G  G  G KGL G PG PGV   + GP G     G +G +G PG 
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV-KGLPGPKGELALSGEKGDQGPPGD 600

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE-KGGVG 1600
            PG+PGS       G  G+ GPQG  G+ G  G+ G+ G  G  GPRGE  V     G  G
Sbjct: 601  PGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG 659

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG--AVGFPGPRGLQGNDGSPGY--- 1655
              GP G PGP G  G  G LG  G+ G PG  GE G   +GFPGP G +G+ G PG    
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1656 -------------GSVGRKGAKGQE-----------GFPGE---SGPKGEIGDPGGPGET 1688
                         G  G  GAKG+            GFPGE   SG  GEIG PG PG  
Sbjct: 720  LGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLP 779

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGR--KGVKGAKGLASFSTCELIQYVR------- 1739
            G  G  G     G PG+ G PGE GPPGR  +G +GA+GL   +  +  Q  R       
Sbjct: 780  GTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKG 839

Query: 1740 -------DRS--PGRHGKPECPVHPTEL 1758
                   DRS  PG  G P  P H  E+
Sbjct: 840  DPGIPGLDRSGFPGETGSPGIPGHQGEM 867



 Score =  253 bits (647), Expect = 1e-66
 Identities = 162/396 (40%), Positives = 189/396 (47%), Gaps = 69/396 (17%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT+G PG  G+ G PG  G +G  GE G + E   PGP G  G  G  G  G KG  
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G +G  G +G  G  G  GLPG+ G  GD G +G  G  G PG RG  GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1512 GAPGV--------DSSIEGPTGLKGE----------------RGRQGRRGWPGPPGTPGS 1547
            G+PG            I GP G KGE                +G +G RG PG PG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1548 RRKTAAHGRRGHTGPQGTAGIP--------------GPDGLEGSLGLKGPQGPRGE--AG 1591
            +      G RG TG +G  G P              GP G  GS G  GP GP G    G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1592 VKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDG 1651
            +KG+KG +G  GP+GPPG  G+ G  GRLG+ G  G PG  G+ G  GFPG +G +GN G
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1652 SPGY----GSVGRK------------------GAKGQEGFPGESGPKGEIGDPGGPGETG 1689
              G     G +G K                  G+ G  G PGE G +GE G PG PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1690 LKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              G RGK      PG+ G PG PGP G KG KG+KG
Sbjct: 1386 PCGPRGK------PGKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  250 bits (639), Expect = 1e-65
 Identities = 166/414 (40%), Positives = 195/414 (47%), Gaps = 68/414 (16%)

Query: 1392 GGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG-C 1441
            GG GT G PG  G  G          PG  G+ G  G +G  G+ G PGP GEQG  G C
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 1442 YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPG--RKGEKGDEGSQGSPGKRGTP 1499
               +GP+G +GL G  G  G+ G  G  G +GD G+PG  R G  G+ GS G PG +G  
Sbjct: 810  I--EGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1500 GDRGAKGLRGDPGA---PGVDSSIE--------GPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G +G  G+PG    PG D  I         GP G  G  G  G+RG PG PG  G R
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 1549 RKTAAHGRRGHTGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
                A G +G  G  G +      G  G  GL+G  G  G +G RG  G+ G KG  G  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 1603 GPQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGAVGFPGP---------R 1644
            GP GPPGP G+ G+ G  G         S GN G PG  G++G +GFPG           
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 1645 GLQGNDGSPGYGS---VGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAG 1701
            GLQG+ G PGY      G  G  G  G PG+ G KGE+G PG PG  G  G  G   + G
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG---APG 1104

Query: 1702 LPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
             PG  G PG+PGP G  G KG KGL                PG  G P  P  P
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLG-------------PPGIRGPPGLPGFP 1145



 Score =  247 bits (630), Expect = 1e-64
 Identities = 162/377 (42%), Positives = 190/377 (50%), Gaps = 39/377 (10%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGF---KGSEGYLGEEGIAGERGAPGP---------VG 1434
            F   IG  G  G+PG PG+RG PG    KG  G  G +G  G++G PGP          G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 1435 EQGTKGCYGTKGPKGNRGLNGQEGEVGENGID---GLNGEQGDNGLPGRKGEKGDEGSQG 1491
            E G KG  G  G KGNRG+ G  G  G  G+    G  G +GD G  G  GE G  G  G
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG-----RRGWPGPPGTPG 1546
            S G  G PG +G +G  G PG  G    + G  GL+G++G  G     R G PGP G PG
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAG-RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
                    G  G  GP G  G  GP+G     GS GL G  GP G+ G KG KG +G  G
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1604 PQGPPG-PG--GEAGNQGRLGSQGNKGEPGDLGEKGAVGF----PGPRGLQGNDGSPG-Y 1655
             +GPPG PG  G  G  G  G QG  G PG  GEKG  G     PGPRG  G  G+ G  
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 1656 GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGA--RGKMISAGLPGEMGSPGEPG 1713
            G+ G  G  G++G  G++GP+G  G  G PG  GL GA   G+  + G PG  GSPG PG
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 1714 PPGRK-----GVKGAKG 1725
            PPG       G+KG KG
Sbjct: 1255 PPGPPGSHVIGIKGDKG 1271



 Score =  244 bits (623), Expect = 7e-64
 Identities = 158/413 (38%), Positives = 195/413 (47%), Gaps = 55/413 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG +G  G  G  GY G  GI G  G  G +G  G  G  G  GP GN 
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS------------QGSPGKRGTP 1499
            G  GQ G        G+ G +G  G PG KGE+GD+G+            +G PG +G  
Sbjct: 910  GTPGQRGS------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 1500 GDRGAKGLRGDPGAPGVD--SSIEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKT 1551
            G+ G KG RG PG PG+     + GP G  G RG  G  G PG       PG+ G+    
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLK-----------GPQGPRGEAGVKGEKGGVG 1600
             + G+RG  G  G AG PG  G+ G  G K           GP GP G+ G+ G+ G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEP------GDLGEKGAVGFPGPRGLQGNDGSPG 1654
              G  GPPG  G AG +G  GS G+ G P      GDLG KG  G  GP G++G  G PG
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 1655 Y----GSVGRKGAKGQEGFPGESGPKGEI-------GDPGGPGETGLKGARGKMISAGLP 1703
            +    G +G +G +G++G PG +G KGE        G  G PG  G KG RG     GLP
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLP 1203

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRS-PGRHGKPECPVHP 1755
            G  G+ G+ GP G  G++G  G        +     +R  PG  G P  P  P
Sbjct: 1204 GRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256



 Score =  239 bits (609), Expect = 3e-62
 Identities = 165/426 (38%), Positives = 199/426 (46%), Gaps = 53/426 (12%)

Query: 1379 AERTCCCLF---CKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE 1435
            A + C C     C C   DG  G+ G  G  GPPG  G +G+ G EG+      PGP G 
Sbjct: 27   ASKGCVCKDKGQCFC---DGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQGP 77

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGS 1492
            +G  G  G  G KG RG++G  G  G  G+ G  G  G  GL   PG  G KG++G  G 
Sbjct: 78   KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL 137

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIE-------GPTGLKGERGRQGRRGWPGPPGTP 1545
            PG  G PG  GA GL+G  GAP  +  IE       G  G  G +G  G  G+PGP G P
Sbjct: 138  PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPP 197

Query: 1546 GSRRKTAAHGRRGHTGPQGTAG--IPGPDGLEGSLGLKGPQGPRG-----------EAGV 1592
            G        G  G  GP+G  G  + G  G  G  GL GP GP G              +
Sbjct: 198  GPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDL 257

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQ--GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
            KGEKG  G+ G  GPPGP G  G       G+ G+ G  G  G+ G  GFPG  G++GN 
Sbjct: 258  KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317

Query: 1651 GSPG-YGSVGRKGAKGQEGFPGESGP---------KGEIGDPGGPGETGLKGARGKMISA 1700
            G PG  G  G KG KG  G PG  GP         KG+ G PG PG  G +G +G     
Sbjct: 318  GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377

Query: 1701 GLPGEMGS--PGEPGPPGRKGVKGAKGLASFSTCELIQYVRD----RSPGRHGKPECPVH 1754
            G+PG  GS  PG  G PG  G+KG+KG       + +          SPG  G P  P  
Sbjct: 378  GVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGP 437

Query: 1755 PTELVF 1760
            P ++VF
Sbjct: 438  PGDIVF 443



 Score =  114 bits (285), Expect = 1e-24
 Identities = 74/185 (40%), Positives = 83/185 (44%), Gaps = 4/185 (2%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  GT GD GPPG+ G PG  G  G  G+ G  G  G  G  G  G  G  G  GP G +
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  G+ G   I  L G  G  G PG  G +G+ G  G PG  G  G RG  G  G P
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG--HTGPQGTAGIP 1569
            G PG  +  +G  G KGE G  G  G PG  G  G     A    RG   T    T  IP
Sbjct: 1400 GTPG-PAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458

Query: 1570 G-PDG 1573
              P+G
Sbjct: 1459 SCPEG 1463



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 51/120 (42%), Positives = 57/120 (47%), Gaps = 9/120 (7%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQG 1437
            F   IG  G +G  GPPG RG          PG  G  G  GE G+ GE G PGP G  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1438 TKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRG 1497
              G  G  G  G  G  G  GE G  G  G  G  G +GLPG KG++GD GS  +   RG
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  263 bits (673), Expect = 1e-69
 Identities = 156/346 (45%), Positives = 184/346 (53%), Gaps = 15/346 (4%)

Query: 1393 GDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE------QGTKGCYGTKG 1446
            GD + GDPG  G  G PG  G  G  GEEG  G RG+PGP G        G  G  G  G
Sbjct: 1007 GDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPG 1066

Query: 1447 PKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKG 1506
             +G RGL G  G+ GE G  G  G  G  G PG  G KG+ G  GS G++G PG  G++G
Sbjct: 1067 LQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEG 1126

Query: 1507 LRGDPG--APGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQG 1564
            L G PG   P  +   +G +G KG++G QG+ G+PGPPG PG   K  + G  G    +G
Sbjct: 1127 LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKG 1186

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
            + GI GP GL GS G  GP G +G AG+ G  G  G  G +G PGP G  G  G  G +G
Sbjct: 1187 SEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKG 1246

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPG- 1683
              G PG  G KG  G PGP G  G  G+   G  G  G +G+ G PG  GP G  G PG 
Sbjct: 1247 KTGHPGLPGPKGDCGKPGPPGSTGRPGAE--GEPGAMGPQGRPGPPGHVGPPGPPGQPGP 1304

Query: 1684 -GPGETGLK---GARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             G    GLK   GA G+   AGLPG+ G PG PGPPG  G  GA G
Sbjct: 1305 AGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAG 1350



 Score =  259 bits (663), Expect = 2e-68
 Identities = 162/420 (38%), Positives = 193/420 (45%), Gaps = 54/420 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG  GPPG  G +G  G  G AGE+G PGP G +G  G  G  GP+G R
Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  GE G+ G  G  G  G  G PG  G+ G  G  G   ++G+ G RG  GL G P
Sbjct: 1141 GPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSP 1200

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGR---RGWPGPPGTPGSRRKTAAHGRRGHTG---PQGT 1565
            G PG    I+GP GL G  G+ G+   RG PGP G PG        G+ GH G   P+G 
Sbjct: 1201 GPPG-PPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGD 1259

Query: 1566 AGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGG--------EAGNQ 1617
             G PGP G  G  G +G  G  G  G  G  G VG  GP G PGP G        + G  
Sbjct: 1260 CGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGAT 1319

Query: 1618 GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGES 1673
            G  G  G  G+PG  G  G  G PG  G  G +G PG    YG  G KG  G  G  G++
Sbjct: 1320 GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQA 1379

Query: 1674 GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG-------L 1726
            G KG  G PGGPG++G  G  G    AG  G  G+PG  G PG  GV G+ G       +
Sbjct: 1380 GEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEI 1439

Query: 1727 ASFSTCELIQYV----------------------------RDRSPGRHGKPECPVHPTEL 1758
              F   E+I+                              +D +PGR G P  P  P ++
Sbjct: 1440 KRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQI 1499



 Score =  250 bits (639), Expect = 1e-65
 Identities = 160/438 (36%), Positives = 203/438 (46%), Gaps = 63/438 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGA---------PGPVGEQGTKGCY 1442
            G  G  G PGPPG  GPPGF G+ G  G  G+ GERG          PGP G+ G  G  
Sbjct: 1036 GPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  G  G +G  G  G  GE G  G  G +G  G PG  G +G+ G QG+ G++G  G +
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 1503 GAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQGRRG------WPGPPGTPGSR------ 1548
            G  G  G PG PG    +   GP G + E+G +G RG       PGPPG PG +      
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 1549 ---RKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQ 1605
                K    G RG  GP G  G+ GP G +G  G  G  GP+G+ G  G  G  G  G +
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 1606 GPP---GPGGEAGNQGRLGSQGNKGEPGDL--------GEKGAVGFPGPRGLQGNDGSPG 1654
            G P   GP G  G  G +G  G  G+PG          G++GA G  G  GL G  G PG
Sbjct: 1276 GEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335

Query: 1655 Y----GSVGRKGAKGQEGFPGES---GPKGEIGDPGGPGETGLKGARGKMISAGLPGEMG 1707
            +    G  G  GA G+EG PG+    GP G  GDPG  G+ G  G +G+    G PG+ G
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395

Query: 1708 SPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALDH--- 1764
            S G  GPPG  G +G  G                +PG  G P  P  P  +   +++   
Sbjct: 1396 SMGPVGPPGPAGERGHPG----------------APGPSGSPGLPGVPGSMGDMVNYDEI 1439

Query: 1765 SRDVTEQEFERMKEMMAF 1782
             R + ++  +   E MA+
Sbjct: 1440 KRFIRQEIIKMFDERMAY 1457



 Score =  244 bits (622), Expect = 9e-64
 Identities = 164/435 (37%), Positives = 180/435 (41%), Gaps = 95/435 (21%)

Query: 1392 GGDGTMGDPGPPGKRGPPGF---------------KGSEGYLGEEGIAGERGAPGPVGEQ 1436
            G  G  G PG PG  GPPGF               KGSEG  G  G+ G  G PGP G Q
Sbjct: 1150 GDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQ 1209

Query: 1437 GTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKR 1496
            G  G  G  G  G  GL G  G  G  G+ G  G +G  G PG  G KGD G  G PG  
Sbjct: 1210 GPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGST 1269

Query: 1497 GTPGDRGAKGLRGDPGAPGVDSSIEGP-------------TGLKGERGRQGRRGW----- 1538
            G PG  G  G  G  G PG    +  P              GLKG+RG  G RG      
Sbjct: 1270 GRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPG 1329

Query: 1539 ----PGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKG 1594
                PG PG PG      A G+ G  G QG  G PGP G  G+ G KG  G +G AG+ G
Sbjct: 1330 QPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPG 1389

Query: 1595 EKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG------------------ 1636
              G  GS GP GPPGP GE G+ G  G  G+ G PG  G  G                  
Sbjct: 1390 GPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIK 1449

Query: 1637 ---------------------AVGFPGPRGLQGNDGSPG----------YGSVGRKGAKG 1665
                                 A G PGP G  G  G PG           G  GR+G  G
Sbjct: 1450 MFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPG 1509

Query: 1666 QEGFPGESGPKGEIGD--------PGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGR 1717
              G PG  G KG+IG         PG PG  G  G  GKM + G  G+ G PG PGPPG 
Sbjct: 1510 VRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGP 1568

Query: 1718 KGVKGAKGLASFSTC 1732
             G  G  G  + S C
Sbjct: 1569 MGQPGKAGHCNPSDC 1583



 Score =  234 bits (598), Expect = 6e-61
 Identities = 162/390 (41%), Positives = 194/390 (49%), Gaps = 50/390 (12%)

Query: 1393 GDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRG 1452
            G    G PG PG+ G PG KG +G  GE G AG  G PGPVG  G KG  G         
Sbjct: 579  GSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPAL 638

Query: 1453 LNGQEGEVGENGIDGLNGEQGDNG-----LPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
             N Q+G+V    + G +GE+G+ G     LPG++G+ G+ G +G  G  G PGD G  G 
Sbjct: 639  SNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGT 698

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAG 1567
             G PG  G +  ++GP G KGE+G  G    P   GT      T   GR G  GP+G  G
Sbjct: 699  TGRPGLSG-EPGVQGPAGPKGEKG-DGCTACPSLQGTV-----TDMAGRPGQPGPKGEQG 751

Query: 1568 IPGPD--GLEGSLGLKGPQGPRGEAGVKGEKG--GVGSKGPQGPPGPGGEAGNQGRLGSQ 1623
              G    G  G  GL G QGP G  GV+GE G  G G +GPQG PG  G  G QG     
Sbjct: 752  PEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGL---P 808

Query: 1624 GNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG---YGSVGRKGAKGQEGF---PGESGPKG 1677
            G +G PG  GEKGA G PG +G  G  G PG    G  GR G +GQ G    PGE GP+G
Sbjct: 809  GPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRG 868

Query: 1678 EIGDPGG---PGE-----TGLKGARGK-MISAGLPGEMGSPGEPGPPGRKGVKGAKGLAS 1728
            E G+PG    P +     +G+ GA G  M S+  PG  G PG PGPPG  GV G +G+  
Sbjct: 869  EKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGV-- 926

Query: 1729 FSTCELIQYVRDRSPGRHGKPECPVHPTEL 1758
                          PG +G P  P    EL
Sbjct: 927  --------------PGNNGLPGQPGLTAEL 942



 Score =  224 bits (572), Expect = 6e-58
 Identities = 164/458 (35%), Positives = 180/458 (39%), Gaps = 124/458 (27%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVG-----------EQGTKG 1440
            G  G  G  G PG RGPPG  G +G  G  G+ G  G  GP G           +QG  G
Sbjct: 797  GAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTG 856

Query: 1441 CYGTKGPKGNRGLNGQEGEV---------------------------------------G 1461
              GT G KG RG  G+ GE                                        G
Sbjct: 857  LRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPG 916

Query: 1462 ENGIDGLNGEQGDNGLPGR-------------------------------------KGEK 1484
              G+ GL G  G+NGLPG+                                     KGEK
Sbjct: 917  PPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEK 976

Query: 1485 GDEGSQGSPG-----------------------KRGTPGDRGAKGLRGDPGAPGVDSSIE 1521
            GD+G  G PG                         G PG  G+ GL G PG PG     E
Sbjct: 977  GDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGE-E 1035

Query: 1522 GPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLK 1581
            GP G++G  G  G  G PG PG  GS       G RG TG  G  G PGP G  G  G  
Sbjct: 1036 GPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 1582 GPQGPRGEAGVKGEKGGVGSKGPQGP------PGPGGEAGNQGRLGSQGNKGEPGDLGEK 1635
            GP G  G  G +G  G  G KG  GP      PGP G AG +G  G QGN GE GD G +
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 1636 GAVGF---PGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGET 1688
            G  GF   PGP G  G  GSPG        G +G +G  G PG  GP G  G  G  G  
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL 1726
            GL G  GK    G PG  G PG  GPPG KG  G  GL
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253



 Score =  219 bits (559), Expect = 2e-56
 Identities = 157/440 (35%), Positives = 185/440 (42%), Gaps = 108/440 (24%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG +GPPG KG +G  G  G    RG  GP GE G  G  G +G  G 
Sbjct: 755  VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG----RGVQGPQGEPGAPGLPGIQGLPGP 810

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGR--KGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            RG  G  GE G  G  G+ G  G  G PG    G  G +G QG  G RGTPG++G +G +
Sbjct: 811  RGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEK 870

Query: 1509 GDP--------------GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAH 1554
            G+P              G PG      G +   G +G  G  G PGPPG PG +     +
Sbjct: 871  GEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNN 930

Query: 1555 G----------------------------------------RRGHTGPQGTAGIPGPD-- 1572
            G                                         +G  G QG  G+PG D  
Sbjct: 931  GLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNC 990

Query: 1573 ------------------------GLEGSLGLKGP---QGPRGEAGVKGEKGGVGSKGPQ 1605
                                    G  GS GL GP    G RGE G  G +G  G  GP 
Sbjct: 991  AQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPI 1050

Query: 1606 GPPG-PG--------GEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY- 1655
            GPPG PG        G  G +G  G  G+KGEPG  G+ G  G  GP GL G  G  GY 
Sbjct: 1051 GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYT 1110

Query: 1656 GSVGRK---GAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSP--- 1709
            GS G K   G  G EG PG  GP G  G+ G  G +G KG +G     G PG  G P   
Sbjct: 1111 GSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFP 1170

Query: 1710 ---GEPGPPGRKGVKGAKGL 1726
               G PGPPG +  KG++G+
Sbjct: 1171 GKVGSPGPPGPQAEKGSEGI 1190



 Score =  217 bits (552), Expect = 1e-55
 Identities = 150/402 (37%), Positives = 184/402 (45%), Gaps = 84/402 (20%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G +G  G+PGPPG  GPPG  G  G  G+ G     G PGP G++G+ G  G +GP G 
Sbjct: 440  VGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPG-----GPPGPKGDKGSSGIPGKEGPGGK 493

Query: 1451 RGLNGQEGEVGE------NGIDGLNGEQGDNGLPGRKGEKGDE-GSQGSPGKRGTPGDRG 1503
             G  G +GE G+         +G     G  G PG KGE GD   ++G PG +G  G++G
Sbjct: 494  PGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKG 553

Query: 1504 -----------------AKGLRGDPGAPGVD----SSIEGPTGLKGERGRQGRRGWPGPP 1542
                             + G  GD G+PG          G  GLKGE+G  G  G  G P
Sbjct: 554  EPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSP 613

Query: 1543 GTPGSRRKTAAHGRRGH---------------------TGPQGTAGIPGPDGLEGSLGLK 1581
            G PG        G +G                       GP G  G PGP G     GL 
Sbjct: 614  GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPG----FGLP 669

Query: 1582 GPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE------- 1634
            G QG  GE G+KG+KG  G+ G  G PG  G  G  G  G QG  G  G+ G+       
Sbjct: 670  GKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPS 729

Query: 1635 --------KGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGP---KGEIGDPG 1683
                     G  G PGP+G QG +G      VGR G  GQ G PG  GP   KG  G+PG
Sbjct: 730  LQGTVTDMAGRPGQPGPKGEQGPEG------VGRPGKPGQPGLPGVQGPPGLKGVQGEPG 783

Query: 1684 GPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             PG  G++G +G+  + GLPG  G PG  GPPG  G KGA+G
Sbjct: 784  PPGR-GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQG 824



 Score =  211 bits (536), Expect = 9e-54
 Identities = 145/408 (35%), Positives = 167/408 (40%), Gaps = 99/408 (24%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPK 1448
            G  G  GDPGP   PG  GPPGFKG  G+ G  G  G+ G PGP G  G  G  G  G  
Sbjct: 1222 GKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAM 1281

Query: 1449 GNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLR 1508
            G +G  G  G VG  G  G  G  G + +    G KGD G+ G  G  G PG  G  G  
Sbjct: 1282 GPQGRPGPPGHVGPPGPPGQPGPAGISAV----GLKGDRGATGERGLAGLPGQPGPPGHP 1337

Query: 1509 GDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI 1568
            G PG PG D    G  G +G  G+QG  G PGP G PG      A G++G  G +G AG+
Sbjct: 1338 GPPGEPGTD----GAAGKEGPPGKQGFYGPPGPKGDPG------AAGQKGQAGEKGRAGM 1387

Query: 1569 PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG------------------------- 1603
            PG  G  GS+G  GP GP GE G  G  G  GS G                         
Sbjct: 1388 PGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEI 1447

Query: 1604 -----------------------PQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGF 1640
                                     G PGP G+ G  GR G+ G+ G PG +G +G  G 
Sbjct: 1448 IKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGL 1507

Query: 1641 PGPRGLQGNDGS-----------------------PGYGSVGRKGAKGQEGFPGESGPKG 1677
            PG RGL G  G                        PGYG +G  G  GQ+G PG  GP G
Sbjct: 1508 PGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPG 1567

Query: 1678 EIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
             +G PG  G        G M           P E   P  K +KG  G
Sbjct: 1568 PMGQPGKAGHCNPSDCFGAM-----------PMEQQYPPMKTMKGPFG 1604



 Score =  210 bits (534), Expect = 1e-53
 Identities = 152/447 (34%), Positives = 188/447 (42%), Gaps = 102/447 (22%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            GG G  G PGPPG +G  G +G++  +     A  + A GP GE+G  G  G  G  G+ 
Sbjct: 337  GGKGERGLPGPPGSKGEKGARGND-CVRISPDAPLQCAEGPKGEKGESGALGPSGLPGST 395

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGR------KGEKGD------EGSQGSPGKRGTP 1499
            G  GQ+GE G+ GI G+ G+ G +G PG       KG+KGD      EG  G PG  G P
Sbjct: 396  GEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLP 455

Query: 1500 GDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAA------ 1553
            G  G  GL G PG PG     +G  G  G  G++G  G PG PG  G +           
Sbjct: 456  GPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLP 514

Query: 1554 ------HGRRGHTGPQGTAGIP----GPDGLEG--------------------------- 1576
                   G  G  GP+G  G P    G  G++G                           
Sbjct: 515  EGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGA 574

Query: 1577 -------SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEP 1629
                     GL G  G  G  G+KGEKG  G  GP G PGP G  G  G  G++G   EP
Sbjct: 575  SGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEP 634

Query: 1630 GDL------GEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPG 1683
                     G+   V  PGP G +G  G PG+G  G++G  G+ G  G+ G  G  GDPG
Sbjct: 635  CPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPG 694

Query: 1684 GPGET---GLKGARGKMISAGLPGEMGS---------------PGEPGPPGRKGVKGAKG 1725
             PG T   GL G  G    AG  GE G                 G PG PG KG +G +G
Sbjct: 695  TPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG 754

Query: 1726 LASFSTCELIQYVRDRSPGRHGKPECP 1752
            +                PG+ G+P  P
Sbjct: 755  VG--------------RPGKPGQPGLP 767



 Score =  171 bits (434), Expect = 6e-42
 Identities = 135/392 (34%), Positives = 166/392 (42%), Gaps = 84/392 (21%)

Query: 1412 KGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN---RGLNGQEGEVGENGIDG- 1467
            K   G    +  A +   P   G + +       GPKG    RGL G  G  GE G  G 
Sbjct: 300  KAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGN 359

Query: 1468 ----------LNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVD 1517
                      L   +G  G  G  G  G  G  GS G++G  G++G  G++G PG PG D
Sbjct: 360  DCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRD 419

Query: 1518 S-----SIEGPTGLKGER---GRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
                   + GP G KG+    G +G  G PGPPG PG        G  G  G  G  G P
Sbjct: 420  GRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPG----PPGIGLPGTPGDPG--GPP 473

Query: 1570 GPDGLEGSLGLKGPQGP---RGEAGVKGEKGG------------------VGSKGPQGPP 1608
            GP G +GS G+ G +GP    G+ GVKGEKG                    G  GP+G P
Sbjct: 474  GPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEP 533

Query: 1609 G-PGGEAGNQGRLGSQGNKGEP--GDLGEKGAVGFPGPRGLQGNDGSPGY------GSVG 1659
            G P    G+ G  G +G KGEP        GA       G  G+ GSPG+      G  G
Sbjct: 534  GDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAG 593

Query: 1660 RKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMIS---------------AGLPG 1704
              G KG++G  GE+GP G  G PG  G  G+KGA+G+                    LPG
Sbjct: 594  VPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPG 653

Query: 1705 EMGSPGEPGPP-----------GRKGVKGAKG 1725
              G  GEPGPP           G +G+KG KG
Sbjct: 654  PSGEKGEPGPPGFGLPGKQGKAGERGLKGQKG 685



 Score =  169 bits (428), Expect = 3e-41
 Identities = 120/321 (37%), Positives = 150/321 (46%), Gaps = 54/321 (16%)

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G    K  RG    +    +     ++G +  N      G KG +G +G PG  G+ G++
Sbjct: 295  GRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEK 354

Query: 1503 GAKG---LRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGH 1559
            GA+G   +R  P AP      EGP G KGE G  G  G PG  G  G +      G +G 
Sbjct: 355  GARGNDCVRISPDAPL--QCAEGPKGEKGESGALGPSGLPGSTGEKGQK------GEKGD 406

Query: 1560 TGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGR 1619
             G +G  G PG DG  G + + GP+G +G+ G  G +G  G  GP G PGP G  G  G 
Sbjct: 407  GGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPG-IGLPGT 465

Query: 1620 LGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQ---------EGF- 1669
             G  G  G PG  G+KG+ G PG  G  G  G PG      KG KG          EGF 
Sbjct: 466  PGDPG--GPPGPKGDKGSSGIPGKEGPGGKPGKPGV-----KGEKGDPCEVCPTLPEGFQ 518

Query: 1670 -----PGESGPKGEIGDP----GGPGETGLKGARGK--------------MISAGLPGEM 1706
                 PG+ GPKGE GDP    G PG  G+KG +G+              + S G  G++
Sbjct: 519  NFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDV 578

Query: 1707 GSP--GEPGPPGRKGVKGAKG 1725
            GSP  G PG PGR GV G KG
Sbjct: 579  GSPGFGLPGLPGRAGVPGLKG 599



 Score =  120 bits (301), Expect = 2e-26
 Identities = 93/274 (33%), Positives = 119/274 (43%), Gaps = 49/274 (17%)

Query: 1510 DPGAPGVDSSIEGPTGLKGERGRQGRRGWPG---PPGTPGSRRKTAAHGRRGHTGPQGTA 1566
            +P    VD+ + G    K ERG +  +       PP   G+R         G  G +G  
Sbjct: 283  EPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGER 342

Query: 1567 GIPGPDGLEGSLGLKGPQGPRG-----------------EAGVKGEKGGVGSKGPQGPPG 1609
            G+PGP G +G          +G                   G KGEKG  G+ GP G PG
Sbjct: 343  GLPGPPGSKGE---------KGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPG 393

Query: 1610 PGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGF 1669
              GE G +G  G  G KG PG  G  G  G     G +G  G PG+  VG +G  G+ G 
Sbjct: 394  STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF--VGPEGLAGEPGP 451

Query: 1670 PGESGPKGEIGDPGGPGET-GLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLAS 1728
            PG  GP G IG PG PG+  G  G +G   S+G+PG+ G  G+PG PG KG KG      
Sbjct: 452  PGLPGPPG-IGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKG------ 504

Query: 1729 FSTCELIQYVRD---------RSPGRHGKPECPV 1753
               CE+   + +           PG  G+P  PV
Sbjct: 505  -DPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPV 537



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 61/196 (31%), Positives = 79/196 (40%), Gaps = 11/196 (5%)

Query: 1541 PPGTPGSRRKTAAHGRRGHTGPQGTAGI-------PGPDGLEGSLGLKGPQGPRGEAGVK 1593
            PP T  +RR T ++       PQ    +         P   E    L G    + E G K
Sbjct: 248  PPETSKARRDTQSN-ELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAK 306

Query: 1594 GEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSP 1653
              +    +   + PP   G   +   L   G KG  G+ G  G  G  G +G +GND   
Sbjct: 307  VHQE---TAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVR 363

Query: 1654 GYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPG 1713
                   + A+G +G  GESG  G  G PG  GE G KG +G     G+PG+ G  G PG
Sbjct: 364  ISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPG 423

Query: 1714 PPGRKGVKGAKGLASF 1729
                 G KG KG   F
Sbjct: 424  EICVIGPKGQKGDPGF 439



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 40/92 (43%), Positives = 47/92 (51%), Gaps = 14/92 (15%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            IG +G     G PG RG PG KG +G +G  GIAGE G PGP G QG  G          
Sbjct: 1499 IGREGRQ---GLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPG---------- 1544

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKG 1482
             G  G  G +G+ GI G+ G  G  G PG+ G
Sbjct: 1545 YGKMGATGPMGQQGIPGIPGPPGPMGQPGKAG 1576



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 28/61 (45%), Positives = 37/61 (60%), Gaps = 8/61 (13%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGF--KGSEGYLGEEGIAGERGAPGPVGEQGTKG------CY 1442
            IG  G  G PGPPG +GPPG+   G+ G +G++GI G  G PGP+G+ G  G      C+
Sbjct: 1525 IGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCF 1584

Query: 1443 G 1443
            G
Sbjct: 1585 G 1585


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  263 bits (671), Expect = 2e-69
 Identities = 156/357 (43%), Positives = 193/357 (54%), Gaps = 42/357 (11%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G MG PGPPG  GP G +G+ G  G  G+ G+   PGP G+ G KG  G  GP G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK---PGPHGDLGFKGIKGLLGPPGI 1135

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS-QGSPGKRGTPGDRGAKGLRG 1509
            RG  G  G  G  G  G+ G+QG +G+PG  GEKG+ G  +  PG RG PG +GAKG RG
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 1510 DPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIP 1569
             PG PG+    +G  G  G RG  G  G+PGPPG PG+       G+ G+ GP G+ G P
Sbjct: 1196 APGFPGLPGR-KGAMGDAGPRGPTGIEGFPGPPGLPGA----IIPGQTGNRGPPGSRGSP 1250

Query: 1570 GPDGLEGSLGLKGPQGPRGE--AGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKG 1627
            G  G         P GP G    G+KG+KG +G  GP+GPPG  G+ G  GRLG+ G  G
Sbjct: 1251 GAPG---------PPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301

Query: 1628 EPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEI------G 1680
             PG  G+ G  GFPG +G +GN   PG+ GS+G  G  G +G PG  G  G +      G
Sbjct: 1302 LPGPRGDPGFQGFPGVKGEKGN---PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358

Query: 1681 DPGGPGETGLKGARGKMISAGLPGEM------------GSPGEPGPPGRKGVKGAKG 1725
             PG PG  G  G +G+    G PG +            G PG PGP G KG KG+KG
Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  254 bits (648), Expect = 9e-67
 Identities = 180/448 (40%), Positives = 206/448 (45%), Gaps = 81/448 (18%)

Query: 1390 CIGGDGTMGDPGPPG-------KRGPPGFKGSEGYLGEEGIAGERGA------------- 1429
            C G  G  G PGPPG       ++GPPG  G  GYLG  GI G  G              
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1430 -PGPVGEQGTKGCYGTKGPKGNRG---LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
             PGP G  G  G +G KG  G +G   L G  G  G  G+ G  G  G  G PG KGEKG
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1486 D----EGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGP 1541
            +    EG  G PG  G  G  G KGL G PG PGV   + GP G     G +G +G PG 
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV-KGLPGPKGELALSGEKGDQGPPGD 600

Query: 1542 PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGE-KGGVG 1600
            PG+PGS       G  G+ GPQG  G+ G  G+ G+ G  G  GPRGE  V     G  G
Sbjct: 601  PGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG 659

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG--AVGFPGPRGLQGNDGSPGY--- 1655
              GP G PGP G  G  G LG  G+ G PG  GE G   +GFPGP G +G+ G PG    
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1656 -------------GSVGRKGAKGQE-----------GFPGE---SGPKGEIGDPGGPGET 1688
                         G  G  GAKG+            GFPGE   SG  GEIG PG PG  
Sbjct: 720  LGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLP 779

Query: 1689 GLKGARGKMISAGLPGEMGSPGEPGPPGR--KGVKGAKGLASFSTCELIQYVR------- 1739
            G  G  G     G PG+ G PGE GPPGR  +G +GA+GL   +  +  Q  R       
Sbjct: 780  GTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKG 839

Query: 1740 -------DRS--PGRHGKPECPVHPTEL 1758
                   DRS  PG  G P  P H  E+
Sbjct: 840  DPGIPGLDRSGFPGETGSPGIPGHQGEM 867



 Score =  250 bits (639), Expect = 1e-65
 Identities = 166/414 (40%), Positives = 195/414 (47%), Gaps = 68/414 (16%)

Query: 1392 GGDGTMGDPGPPGKRGP---------PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG-C 1441
            GG GT G PG  G  G          PG  G+ G  G +G  G+ G PGP GEQG  G C
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 1442 YGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPG--RKGEKGDEGSQGSPGKRGTP 1499
               +GP+G +GL G  G  G+ G  G  G +GD G+PG  R G  G+ GS G PG +G  
Sbjct: 810  I--EGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1500 GDRGAKGLRGDPGA---PGVDSSIE--------GPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G +G  G+PG    PG D  I         GP G  G  G  G+RG PG PG  G R
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 1549 RKTAAHGRRGHTGPQGTA------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
                A G +G  G  G +      G  G  GL+G  G  G +G RG  G+ G KG  G  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 1603 GPQGPPGPGGEAGNQGRLG---------SQGNKGEPGDLGEKGAVGFPGP---------R 1644
            GP GPPGP G+ G+ G  G         S GN G PG  G++G +GFPG           
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 1645 GLQGNDGSPGYGS---VGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAG 1701
            GLQG+ G PGY      G  G  G  G PG+ G KGE+G PG PG  G  G  G   + G
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG---APG 1104

Query: 1702 LPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
             PG  G PG+PGP G  G KG KGL                PG  G P  P  P
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLG-------------PPGIRGPPGLPGFP 1145



 Score =  247 bits (630), Expect = 1e-64
 Identities = 162/377 (42%), Positives = 190/377 (50%), Gaps = 39/377 (10%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGF---KGSEGYLGEEGIAGERGAPGP---------VG 1434
            F   IG  G  G+PG PG+RG PG    KG  G  G +G  G++G PGP          G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 1435 EQGTKGCYGTKGPKGNRGLNGQEGEVGENGID---GLNGEQGDNGLPGRKGEKGDEGSQG 1491
            E G KG  G  G KGNRG+ G  G  G  G+    G  G +GD G  G  GE G  G  G
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG-----RRGWPGPPGTPG 1546
            S G  G PG +G +G  G PG  G    + G  GL+G++G  G     R G PGP G PG
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAG-RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPGPDGL---EGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
                    G  G  GP G  G  GP+G     GS GL G  GP G+ G KG KG +G  G
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1604 PQGPPG-PG--GEAGNQGRLGSQGNKGEPGDLGEKGAVGF----PGPRGLQGNDGSPG-Y 1655
             +GPPG PG  G  G  G  G QG  G PG  GEKG  G     PGPRG  G  G+ G  
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 1656 GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGA--RGKMISAGLPGEMGSPGEPG 1713
            G+ G  G  G++G  G++GP+G  G  G PG  GL GA   G+  + G PG  GSPG PG
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 1714 PPGRK-----GVKGAKG 1725
            PPG       G+KG KG
Sbjct: 1255 PPGPPGSHVIGIKGDKG 1271



 Score =  244 bits (623), Expect = 7e-64
 Identities = 158/413 (38%), Positives = 195/413 (47%), Gaps = 55/413 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PG PG +G  G  G  GY G  GI G  G  G +G  G  G  G  GP GN 
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS------------QGSPGKRGTP 1499
            G  GQ G        G+ G +G  G PG KGE+GD+G+            +G PG +G  
Sbjct: 910  GTPGQRGS------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 1500 GDRGAKGLRGDPGAPGVD--SSIEGPTGLKGERGRQGRRGWPGP------PGTPGSRRKT 1551
            G+ G KG RG PG PG+     + GP G  G RG  G  G PG       PG+ G+    
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLK-----------GPQGPRGEAGVKGEKGGVG 1600
             + G+RG  G  G AG PG  G+ G  G K           GP GP G+ G+ G+ G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEP------GDLGEKGAVGFPGPRGLQGNDGSPG 1654
              G  GPPG  G AG +G  GS G+ G P      GDLG KG  G  GP G++G  G PG
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 1655 Y----GSVGRKGAKGQEGFPGESGPKGEI-------GDPGGPGETGLKGARGKMISAGLP 1703
            +    G +G +G +G++G PG +G KGE        G  G PG  G KG RG     GLP
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLP 1203

Query: 1704 GEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRS-PGRHGKPECPVHP 1755
            G  G+ G+ GP G  G++G  G        +     +R  PG  G P  P  P
Sbjct: 1204 GRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256



 Score =  239 bits (609), Expect = 3e-62
 Identities = 165/426 (38%), Positives = 199/426 (46%), Gaps = 53/426 (12%)

Query: 1379 AERTCCCLF---CKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGE 1435
            A + C C     C C   DG  G+ G  G  GPPG  G +G+ G EG+      PGP G 
Sbjct: 27   ASKGCVCKDKGQCFC---DGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQGP 77

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGL---PGRKGEKGDEGSQGS 1492
            +G  G  G  G KG RG++G  G  G  G+ G  G  G  GL   PG  G KG++G  G 
Sbjct: 78   KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL 137

Query: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIE-------GPTGLKGERGRQGRRGWPGPPGTP 1545
            PG  G PG  GA GL+G  GAP  +  IE       G  G  G +G  G  G+PGP G P
Sbjct: 138  PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPP 197

Query: 1546 GSRRKTAAHGRRGHTGPQGTAG--IPGPDGLEGSLGLKGPQGPRG-----------EAGV 1592
            G        G  G  GP+G  G  + G  G  G  GL GP GP G              +
Sbjct: 198  GPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDL 257

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQ--GRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGND 1650
            KGEKG  G+ G  GPPGP G  G       G+ G+ G  G  G+ G  GFPG  G++GN 
Sbjct: 258  KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317

Query: 1651 GSPG-YGSVGRKGAKGQEGFPGESGP---------KGEIGDPGGPGETGLKGARGKMISA 1700
            G PG  G  G KG KG  G PG  GP         KG+ G PG PG  G +G +G     
Sbjct: 318  GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377

Query: 1701 GLPGEMGS--PGEPGPPGRKGVKGAKGLASFSTCELIQYVRD----RSPGRHGKPECPVH 1754
            G+PG  GS  PG  G PG  G+KG+KG       + +          SPG  G P  P  
Sbjct: 378  GVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGP 437

Query: 1755 PTELVF 1760
            P ++VF
Sbjct: 438  PGDIVF 443



 Score =  238 bits (607), Expect = 5e-62
 Identities = 169/444 (38%), Positives = 196/444 (44%), Gaps = 88/444 (19%)

Query: 1392 GGDGTMGDPGPP------GKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTK 1445
            G  G  G+PGP       G +G PG KG  G  GE+G    RG PG  G +G KG  G  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG---NRGVPGMPGLKGLKGLPGPA 990

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK 1505
            GP G RG  G  G  GE G+ G+ G  G+ G+PG KG++G  G  G  G+ G PG  G +
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1506 GLRGDPG-APGVDSSIEGPTG---LKGERGRQGRRGWPGPPG---------------TPG 1546
            G +G+PG + G      GPTG   L G+ G++G  G PGPPG               +PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1547 SRRKTAAHGRRGHTGPQGTAGIPG---PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKG 1603
               K   HG  G  G +G  G PG   P GL G  G  GP G RG+ G  G  G  G KG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1604 PQG----PPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVG------------FPGPRGLQ 1647
              G    PPGP G  G QG  G +G  G PG  G KGA+G            FPGP GL 
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1648 GN-----------------------DGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPG- 1683
            G                         G PG   +G KG KG  G PG  GP G  GD G 
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 1684 -----GPGETGLKGARGKMISAGLPGEMGSPGEPG------PPGRKGVKGAKGL-ASFST 1731
                  PG  GL G RG     G PG  G  G PG      PPG  G KG  G+     T
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 1732 CELIQYVRDRSPGRHGKPECPVHP 1755
             ++I       PG  G P  P  P
Sbjct: 1351 LKIISL-----PGSPGPPGTPGEP 1369



 Score =  161 bits (407), Expect = 8e-39
 Identities = 103/254 (40%), Positives = 118/254 (46%), Gaps = 32/254 (12%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGT--KGCYGTKGPKG 1449
            G  G  GD G PG  G PG KG+ G  G  G  G  G PGP G  G    G  G +GP G
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG 1245

Query: 1450 NRGLNGQEGEVGENG--IDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
            +RG  G  G  G  G  + G+ G++G  G PG KG  G  G  G PG+ G PG  G  G 
Sbjct: 1246 SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGP 1305

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRG--------- 1558
            RGDPG        +G  G+KGE+G  G  G  GPPG  G +      G  G         
Sbjct: 1306 RGDPG-------FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358

Query: 1559 HTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQG 1618
              GP GT G PG        G  GP GP G  G  G +G  G  G  G PGP GE GN  
Sbjct: 1359 SPGPPGTPGEPGMQ------GEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN-- 1410

Query: 1619 RLGSQGNKGEPGDL 1632
                +G+KGEP  L
Sbjct: 1411 ----KGSKGEPESL 1420



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 15/107 (14%)

Query: 1387 FCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKG 1446
            F   IG  G +G  GPPG RG P      G L    + G  G PG  GE G +G  G  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDP------GTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379

Query: 1447 PKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSP 1493
            P GN G  G  G+ G++         G  G PG  GEKG++GS+G P
Sbjct: 1380 PPGNLGPCGPRGKPGKD---------GKPGTPGPAGEKGNKGSKGEP 1417


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  262 bits (669), Expect = 3e-69
 Identities = 162/399 (40%), Positives = 196/399 (49%), Gaps = 46/399 (11%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G+ G  G PG  G PG KG  G+ G EG  GE GAPG  GE G  G  G  GP G 
Sbjct: 278  VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP 337

Query: 1451 RGLNGQEGEVGENGIDGLNGEQG---------------DNGLPGRKGEKGDEGSQGSPGK 1495
            RG+ G+ G +G  G  G  G  G                +G PG  G KG+ G  G+ G 
Sbjct: 338  RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397

Query: 1496 RGTPGDRGAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQGRRGWPG---PPGTPGSRRK 1550
             G  G RG  G  G  G+PG+  +I  +G  G KG  G  G  G PG   PPG+PG +  
Sbjct: 398  EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457

Query: 1551 TAAHGRRGHTGPQGTAGIPG---PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGP 1607
            T   G RG  G  G  G  G   P G  G  G++GP GP GE G +G +G  G+ GP GP
Sbjct: 458  TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517

Query: 1608 PGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQE 1667
             G  G  GN+G  GS G  G  G  GE+G VG  GP+G QG+ G P  G  G  GA+G  
Sbjct: 518  VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP--GEPGLPGARGLT 575

Query: 1668 GFPGESGPKGEIGDPGGPGETGLK------GARGKMISAGLPGEMGSPGEPGPPGRKGVK 1721
            G PG  GP+G++G  G PGE G        G RG+  S GLPG  GS G+PG PG  G  
Sbjct: 576  GNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 1722 GAKGLASFSTCELIQYVRDRSPGRHGK--PECPVHPTEL 1758
            G  G             +  +PG+ G+  P  PV P  L
Sbjct: 636  GVPG-------------QRGAPGKDGEVGPSGPVGPPGL 661



 Score =  257 bits (656), Expect = 1e-67
 Identities = 155/397 (39%), Positives = 192/397 (48%), Gaps = 68/397 (17%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYG------TK 1445
            G  G  G+ GP G RGP G +G  G  G  G  G  G PG +G  GT G  G      T 
Sbjct: 381  GNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS 440

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE---KGDEGSQGSPGKRGTPGDR 1502
            GP G+ G  G  G  G  G  G+ G+ GD G+PG KGE   KG+ G  G  G  G PG+ 
Sbjct: 441  GPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE 500

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G +G RGDPG  G       P G  GERG  G RG+PG  G PG +      G  G +GP
Sbjct: 501  GKRGPRGDPGTVG-------PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGP 553

Query: 1563 QGTAG---------IPGPDGLEGSLGLKGPQG---------------PRGEAGVKGEKGG 1598
            +G+ G         +PG  GL G+ G++GP+G               P G  G++G+ G 
Sbjct: 554  KGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGS 613

Query: 1599 VGSKGPQGP---PGPGGEAGN------------QGRLGSQGNKGEPGDLGEKGAVGFPGP 1643
            +G  GP+G    PG  GEAGN             G +G  G  G PG  GE+G  G PGP
Sbjct: 614  MGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP 673

Query: 1644 RGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGG---------PGETGL 1690
             G QG  G PG     G  G +G  G  G  G  GP+GE G+PG          PGE G+
Sbjct: 674  TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLA 1727
             G  G     G PG  G+PG+ GPPG +G+ G +G+A
Sbjct: 734  AGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770



 Score =  254 bits (649), Expect = 7e-67
 Identities = 184/503 (36%), Positives = 218/503 (43%), Gaps = 77/503 (15%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP- 1447
            G DG  G PGP   PG  GP G KG  G  G  G  G RG PG  GE G  G  G  GP 
Sbjct: 792  GNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQ 851

Query: 1448 --------KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTP 1499
                    KG  G  GQ+G+ G  G  GL G  G +G  G  G KG  G+QG PG  G P
Sbjct: 852  GPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFP 911

Query: 1500 GDRGAKGLRGDPGAPGVDSSI-----EGPTGLKGERGRQGR---RGWPGPPGTPGSRRKT 1551
            G  G  G  G  GAPG    +     EGP GL+G+ G  GR   RG  GPPG PG +   
Sbjct: 912  GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP 971

Query: 1552 AAHGRRGHTGPQGTA---------GIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSK 1602
               G+ G  GP G A         G+PG  G  G  GL GP G  G+ G  G  G  G  
Sbjct: 972  GEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP 1031

Query: 1603 GPQGPP---GPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----- 1654
            GP GPP   GP GE G +G  G+ G  G  G +GE+G  G PGP GL G+ G+PG     
Sbjct: 1032 GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPV 1091

Query: 1655 --------------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR------ 1694
                           G +G  G  G+ G PG  GP+G+ GD G  G+ G KG R      
Sbjct: 1092 GAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQ 1151

Query: 1695 ---------GKMISAGLPGEMGSPGEPGPPGRKGVKGAKG-LASFSTCELIQYVRDRS-- 1742
                     G+  SAG+PG  G  G PGP G  G +G  G L       +   V +    
Sbjct: 1152 GLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE 1211

Query: 1743 --PGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRE--NSCPVGA 1798
              PG  G P  P  P  L  AL    D+     E M + +     D    +  N    G 
Sbjct: 1212 GPPGEPGPPGPPGPPGHLTAALG---DIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGV 1268

Query: 1799 HIAILSYNSHARHLVRFSDAYKK 1821
            H  + S +S     +R  D  KK
Sbjct: 1269 HATLKSLSSQI-ETMRSPDGSKK 1290



 Score =  253 bits (647), Expect = 1e-66
 Identities = 152/358 (42%), Positives = 177/358 (49%), Gaps = 15/358 (4%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G+MG PGP G  G PG     G  G  G+ G+RGAPG  GE       G  GP G  
Sbjct: 609  GQPGSMGLPGPKGSSGDPG---KPGEAGNAGVPGQRGAPGKDGE------VGPSGPVGPP 659

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G+ GE G  G  G  G  G  G PG  G+ GD+G  G PG  G  G RG +G  G+ 
Sbjct: 660  GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG+ + + G  G+ G  G  G +G PGP GTPG    T   G +G  G +G AG PGP
Sbjct: 720  GEPGI-TGLPGEKGMAGGHGPDGPKGSPGPSGTPGD---TGPPGLQGMPGERGIAGTPGP 775

Query: 1572 DGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGD 1631
             G  G +G KG +G  G  G +G  G +G  GP GP G  GE G +G +G  G++G PG 
Sbjct: 776  KGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGS 835

Query: 1632 LGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL 1690
             GE G  G  G  G QG DG PG  G  G  G KG  G PG  G  G  G  G  G  GL
Sbjct: 836  RGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGL 895

Query: 1691 KGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGK 1748
            KG RG     G  G  GS G  GPPG  G  G  G       E    +R   PG HG+
Sbjct: 896  KGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRG-DPGSHGR 952



 Score =  253 bits (645), Expect = 2e-66
 Identities = 157/370 (42%), Positives = 179/370 (48%), Gaps = 36/370 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAG------ERGAPGPVGEQGTKGCYGTK 1445
            G  G  G PGP G RG  G KG+EG  G +G  G        G  GP GE+G  G  G  
Sbjct: 765  GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLV 824

Query: 1446 GPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGE------KGDEGSQGSPGKRGTP 1499
            GP G+RG  G  GE G  G  G  G QG +G PG KGE      KGD GS G  G  G+P
Sbjct: 825  GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP 884

Query: 1500 GDRGAKGL------RGDPGAPGV-----DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            G  G  G+      RG  G PG       +   GP G  G  G  G  G PG  G PG R
Sbjct: 885  GPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944

Query: 1549 RKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGP- 1607
                +HGR G  GP G  G PG  G  G  G  GP GP G AG  G++G VG  G +G  
Sbjct: 945  GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004

Query: 1608 -----PGPGGEAGNQGRLGSQGNKGEPGDL---GEKGAVGFPGPRGLQGNDGSPGY-GSV 1658
                 PGP G  G  G  G+ G+KG PG +   G  G VG PGP G  GNDG+PG  G+V
Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064

Query: 1659 GRKGAKGQ---EGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPP 1715
            G +G +G     G PG  G  G  G  G PG+ G +G  G     G PG  G  G PGP 
Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQ 1124

Query: 1716 GRKGVKGAKG 1725
            G +G KG  G
Sbjct: 1125 GPRGDKGDHG 1134



 Score =  251 bits (642), Expect = 4e-66
 Identities = 151/362 (41%), Positives = 173/362 (47%), Gaps = 39/362 (10%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGF------------KGSEGYLGEEGIAGERGAPGP---VGE 1435
            +G  G  G  G PG+ G PG             +G EG LG  G  GE G PGP   +G 
Sbjct: 548  VGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGI 607

Query: 1436 QGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGK 1495
            +G  G  G  GPKG+ G  G+ GE G  G+ G  G  G +G  G  G  G  G  G  G+
Sbjct: 608  RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667

Query: 1496 RGTPGDRGAKGLRGDPGAPGV-----------DSSIEGPTGLKGERGRQGRRGWPGPPGT 1544
            +G PG  G +GL G PG PG            D    GP G +GERG  G RG PG  G 
Sbjct: 668  QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727

Query: 1545 PGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
            PG +     HG  G  G  G +G PG  G  G  G+ G +G  G  G KG++GG+G KG 
Sbjct: 728  PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGA 787

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY-GSVGRKGA 1663
            +      G AGN G  G  G  G PG  G  G  G PGPRGL G  GS G  GS G  G 
Sbjct: 788  E------GTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGP 841

Query: 1664 KGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGA 1723
             G  GF G  GP G+ G  G PGE G KG       AG PG  G  G PGP G  GV G 
Sbjct: 842  TGAVGFAGPQGPDGQPGVKGEPGEPGQKG------DAGSPGPQGLAGSPGPHGPNGVPGL 895

Query: 1724 KG 1725
            KG
Sbjct: 896  KG 897



 Score =  251 bits (642), Expect = 4e-66
 Identities = 161/391 (41%), Positives = 183/391 (46%), Gaps = 57/391 (14%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVG---------EQGTKGCY 1442
            G  G  G+ GP G  GPPG  G  G  G  G  G +G PGP G         +QG  G  
Sbjct: 642  GAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDP 701

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
            G  GP G RG  G  GE GE GI GL GE+G  G  G  G KG  G  G+PG  G PG +
Sbjct: 702  GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ 761

Query: 1503 GAKGLRGDPGAPGV--DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGR---R 1557
            G  G RG  G PG   D    G  G +G  G  G RG PGP G PG    T   G    R
Sbjct: 762  GMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPR 821

Query: 1558 GHTGPQGTAGIP---GPDGLEGSLGLKGPQGPRGEAGVKGE------KGGVGSKGP---- 1604
            G  GP G+ G P   G +G  G++G  GPQGP G+ GVKGE      KG  GS GP    
Sbjct: 822  GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA 881

Query: 1605 --------------------QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
                                QGPPG  G  G+ GR+G  G  G PG  G  G  G  GP 
Sbjct: 882  GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941

Query: 1645 GLQGNDGSPGY----------GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
            GL+G+ GS G           G  G KG  G++G PG  GP G  G  G  G  G+ G R
Sbjct: 942  GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001

Query: 1695 GKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            G+    GLPG  G+PG+ GP G  G KG  G
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPG 1032



 Score =  249 bits (637), Expect = 2e-65
 Identities = 154/365 (42%), Positives = 181/365 (49%), Gaps = 35/365 (9%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G++G  G PG  G PG KGS G  G+ G AG  G PG  G  G  G  G  GP G  
Sbjct: 600  GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            GL G+ GE G  G  G  G  G  G PG  G+ GD+G  G PG  G  G RG +G  G+ 
Sbjct: 660  GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGP 1571
            G PG+ + + G  G+ G  G  G +G PGP GTPG    T   G +G  G +G AG PGP
Sbjct: 720  GEPGI-TGLPGEKGMAGGHGPDGPKGSPGPSGTPGD---TGPPGLQGMPGERGIAGTPGP 775

Query: 1572 DGLEGSLG---------------LKGPQGPRGEAGVKGEKGGVGSKGPQGPPG----PG- 1611
             G  G +G               L GP GP G AG  GEKG  G +G  GPPG    PG 
Sbjct: 776  KGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGS 835

Query: 1612 ----------GEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSV-GR 1660
                      G AG QG  G  G KGEPG+ G+KG  G PGP+GL G+ G  G   V G 
Sbjct: 836  RGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGL 895

Query: 1661 KGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGV 1720
            KG +G +G PG +G  G  G  G PG  G  G  G +   G  G  G  G+PG  GR G 
Sbjct: 896  KGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGD 955

Query: 1721 KGAKG 1725
            +G  G
Sbjct: 956  RGPAG 960



 Score =  230 bits (587), Expect = 1e-59
 Identities = 145/376 (38%), Positives = 173/376 (46%), Gaps = 41/376 (10%)

Query: 1383 CCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCY 1442
            CC +  +  GG  T    G  G++G PG            + G RG PGP G  G++G  
Sbjct: 92   CCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPV--------VTGIRGRPGPAGPPGSQGPR 143

Query: 1443 GTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKG----------------EKGD 1486
            G +GPKG  G  G +G  GE G+ G  G  G  G P   G                EK  
Sbjct: 144  GERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSG 203

Query: 1487 EGSQGS--PGKRGTPGDRGAKGLRGDPGAPGV-----DSSIEGPTGLKGERGRQGRRGWP 1539
             GSQ    PG  G  G RG +GL+G  G  G      +    GP G  G RG +G  G P
Sbjct: 204  LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKP 263

Query: 1540 GPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGV 1599
            G  G PG        G  G  G +G  G PG  GL+G  G KG +GP+GE G  G KG  
Sbjct: 264  GEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEA 323

Query: 1600 GSKGP---QGPPGPGGEAGNQGRLGSQGNKGE------PGDLGEKGAVGFPGPRGLQGND 1650
            G  GP    GP GP G  G +GRLG QG  G+      PG  G  G +G PG  G  GN 
Sbjct: 324  GPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP 383

Query: 1651 GSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSP 1709
            G  G  G  G +G +G +G  GE+GP G +G PG PG  G  G  G     G PG  G P
Sbjct: 384  GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP 443

Query: 1710 GEPGPPGRKGVKGAKG 1725
            G  GPPG  G +G+ G
Sbjct: 444  GSAGPPGSPGPQGSTG 459



 Score =  211 bits (536), Expect = 9e-54
 Identities = 127/305 (41%), Positives = 143/305 (46%), Gaps = 36/305 (11%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN 1450
            +G  G  G PG PG +G P         GE+G  G  G PGP G  G +G  G  G +G 
Sbjct: 953  VGDRGPAGPPGGPGDKGDP---------GEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE 1003

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKR------GTPGDRGA 1504
            RG+ G  G  G  G  G  G  GD G PG  G  G  G  G PG        GTPG  GA
Sbjct: 1004 RGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063

Query: 1505 KGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQG 1564
             G RGD G P       GP GL G    QG  G PGP G PG   +    G RG  GP G
Sbjct: 1064 VGERGDRGDP-------GPAGLPGS---QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPG 1113

Query: 1565 TAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQG 1624
             AG  G  G +G  G KG  G RG+ G KG +G  G +G  GPPGP GE G+ G  G  G
Sbjct: 1114 RAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFG 1173

Query: 1625 NKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGG 1684
             +G PG +G  G  G PGP            G +G  G +G  G  G  GP GE G PG 
Sbjct: 1174 PRGPPGPVGPSGKEGNPGP-----------LGPIGPPGVRGSVGEAGPEGPPGEPGPPGP 1222

Query: 1685 PGETG 1689
            PG  G
Sbjct: 1223 PGPPG 1227



 Score =  160 bits (404), Expect = 2e-38
 Identities = 107/297 (36%), Positives = 133/297 (44%), Gaps = 61/297 (20%)

Query: 1479 GRKGEKGDEGS-------QGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERG 1531
            GRKG+KG+ G        +G PG  G PG +G +G RG  G PG      GP G+ GE G
Sbjct: 110  GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGP----RGPQGIDGEPG 165

Query: 1532 RQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGT--------AGIPGPDGLEGSLGLK-- 1581
              G+ G PGPPG P             H GP G         AG+    GL   +GL   
Sbjct: 166  VPGQPGAPGPPGHPS------------HPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPG 213

Query: 1582 --GPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVG 1639
              GP GPRG  G++G++GG G  GP G PG  G  G  G  G +G  G+PG+ GE G  G
Sbjct: 214  SVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG 273

Query: 1640 FPGPRGLQGNDGSPGY-GSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMI 1698
             PG  G  G+ G+ G+ G+ G  G KG  G  G  GPKGE+                   
Sbjct: 274  NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEV------------------- 314

Query: 1699 SAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
              G PG  G  G  GP G  G  G +G+      E  +     +PG+ G    P  P
Sbjct: 315  --GAPGSKGEAGPTGPMGAMGPLGPRGMPG----ERGRLGPQGAPGQRGAHGMPGKP 365



 Score =  132 bits (331), Expect = 5e-30
 Identities = 95/242 (39%), Positives = 110/242 (45%), Gaps = 40/242 (16%)

Query: 1492 SPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKT 1551
            +PG   T   RG KG +G+PG   V + I               RG PGP G PGS+   
Sbjct: 99   TPGGGNTNFGRGRKGQKGEPGLVPVVTGI---------------RGRPGPAGPPGSQ--- 140

Query: 1552 AAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPG 1611
               G RG  GP+G    PGP         +GPQG  GE GV G+ G  G  G    PGP 
Sbjct: 141  ---GPRGERGPKGR---PGP---------RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPD 185

Query: 1612 GEA----GNQGRLGSQGNKGEPGDL--GEKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAK 1664
            G +         L  +   G    L  G  G VG  GP+GLQG  G  G  G  G  G  
Sbjct: 186  GLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDP 245

Query: 1665 GQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAK 1724
            G  G  G  GP+G  G PG  GE G  G  G++  AG PG  G PG PG PG KG +G K
Sbjct: 246  GPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHK 305

Query: 1725 GL 1726
            GL
Sbjct: 306  GL 307



 Score =  118 bits (296), Expect = 6e-26
 Identities = 76/208 (36%), Positives = 93/208 (44%), Gaps = 25/208 (12%)

Query: 1541 PPG--------TPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGV 1592
            PPG        TPG        GR+G  G  G   +     + G  G  GP GP G  G 
Sbjct: 88   PPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPV-----VTGIRGRPGPAGPPGSQGP 142

Query: 1593 KGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGS 1652
            +GE+G  G  GP+GP G  GE G  G+ G+ G  G P   G  G +  P    + G D  
Sbjct: 143  RGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDG-LSRPFSAQMAGLDEK 201

Query: 1653 PGYGS-----------VGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAG 1701
             G GS           VG +G +G +G  G +GP G  G+PG PG  G  G+RG     G
Sbjct: 202  SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG 261

Query: 1702 LPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
             PGE G PG  G PG  G  G+ G   F
Sbjct: 262  KPGEDGEPGRNGNPGEVGFAGSPGARGF 289


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  261 bits (667), Expect = 6e-69
 Identities = 159/353 (45%), Positives = 190/353 (53%), Gaps = 20/353 (5%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGER--GAPGPVGEQGTKG-----CYGT 1444
            G DG  G PG PG  G PG  G +G  G  G  G+   G PG  GE+G  G       G 
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 1445 KGPKGNRGL---NGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGS--QGSPGKRGTP 1499
             G KG+RGL    G++GE G  G  G  GE G  G PG KG KGD G    GSPG  G P
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPP 2385

Query: 1500 GDRGAKGLRGDPGAPGVDS--SIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRR 1557
            G +G  GL G PGAPGV       GP G  G+ G  G RG  GPPG  G        G  
Sbjct: 2386 GVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445

Query: 1558 GHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQ 1617
            G  GP G +G+ G  G  G +GL GP+G RGE G++GE G  G +GP+G  GP G  G +
Sbjct: 2446 GSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504

Query: 1618 GRLGSQGNKGEPGDLGEKGAV-GFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGP 1675
            G  G  G+ G  GD G+   + G PGPRG +G+ G  G  G  G KG +G  G PG+ G 
Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGS 2564

Query: 1676 KGEIGDPGG---PGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
            KGE GD G    PG  GL G +G+  +AG+PG+ GSPG+ G PG +G KG  G
Sbjct: 2565 KGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617



 Score =  260 bits (664), Expect = 1e-68
 Identities = 169/402 (42%), Positives = 201/402 (50%), Gaps = 81/402 (20%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G DG  G PG PG  GPPG K S    G  G++GE+G PG  G +G  G  G +GPKG+R
Sbjct: 2073 GRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDR 2131

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G+ G +G+ GE    G  G+ G+ GLPG +G  G EG  G  G RG PG  G  G  G P
Sbjct: 2132 GVPGIKGDRGE---PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPP 2188

Query: 1512 GAPGV--DSSIEGPTGLKGERGRQGRRG-----------WPGPPGTPGSRRKTAAHGRRG 1558
            GAPG+   +  +GP+GLKGE G  G  G            PGPPG  G      + G  G
Sbjct: 2189 GAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPG 2248

Query: 1559 HTGPQGTAGIPGPDG------------LEGSLGLKGPQGPRGEAG--------------V 1592
              G  G  G PG DG            + GS GL GP GP+GE G               
Sbjct: 2249 QVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGA 2308

Query: 1593 KGEKGGVG-----------SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFP 1641
            KGEKG  G           +KG +G PGP GE G  GR G      EPGD GE G  G P
Sbjct: 2309 KGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAG------EPGDPGEDGQKGAP 2362

Query: 1642 GPRGLQGN-----DGSPG----------YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPG 1686
            GP+G +G+      GSPG           G  G  GA G  GFPG++GP+GE+G PG  G
Sbjct: 2363 GPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSG 2422

Query: 1687 ETGLKGARGKMISAGLPGEMGSPGEP---GPPGRKGVKGAKG 1725
            E GL G  G+    G+PG +G PG P   GPPG  G+KG KG
Sbjct: 2423 ERGLAGPPGR---EGIPGPLGPPGPPGSVGPPGASGLKGDKG 2461



 Score =  256 bits (655), Expect = 1e-67
 Identities = 161/365 (44%), Positives = 185/365 (50%), Gaps = 36/365 (9%)

Query: 1392 GGDGTMGDPGP---PGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKG-CYGTKGP 1447
            G DG  G PG    PG  G PG KGS G  G  G  GERG  GP GE G  G   G +GP
Sbjct: 1302 GADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP 1361

Query: 1448 --KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGR--KGEKGDEGSQGSPGKRGTPGDRG 1503
               G +G  G  G  G  G  G  G +G  GLPG   KG+KGD G +G PG        G
Sbjct: 1362 GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG 1421

Query: 1504 AKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQ 1563
              GL G PG+PG    + GP G KGE+G     G PG PG PGS  +    G  G  GP+
Sbjct: 1422 EPGLPGLPGSPGPQGPV-GPPGKKGEKG-DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479

Query: 1564 GTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQ 1623
            G  G PGP G  G  G +GP GP G  G+ G  G  G+KGP+GPPGP    G QG  G  
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP---TGRQGEKGEP 1536

Query: 1624 GNKGEP--------GDLGEKGAVGFPGPRG---LQGNDGSPGY------------GSVGR 1660
            G  G+P        G  GEKG VG  GPRG   +QG  G PG             G  G 
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 1661 KGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGV 1720
             G  G+ G PG+SGP GE GDPG PG  G  G RG+    G  G+ G PG+PG PG+ G 
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 1721 KGAKG 1725
            +G +G
Sbjct: 1657 RGLRG 1661



 Score =  254 bits (648), Expect = 9e-67
 Identities = 156/364 (42%), Positives = 180/364 (49%), Gaps = 39/364 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G PGP G  GPPG KG +G   E+G  G  G PG  GEQG +G  G  GPKG+R
Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGD-SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G  G  GE GE G  G  G  G  GLPG  G  G +G +G PG  G  G++G  G  GDP
Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 1512 GAPGV-------DSSIEGPTGLKGERGRQGRRGWPG--------PPGTPGSRRKTAAHGR 1556
               G        +    GP G +G  G QG RG PG        P G PG R      GR
Sbjct: 1543 AVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGR 1602

Query: 1557 RG---HTGPQGTAGIPG---------PDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGP 1604
             G    +GP G  G PG         P G +G +G KG +GP G+ G+ G+ G  G +G 
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGA 1662

Query: 1605 QGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGN--DGSPGYGSVGRKG 1662
             G  GP GE G+QG  G  G  G PG  G KG  G PGP G  G   D  PG    G  G
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722

Query: 1663 AKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKG 1722
             +GQEG     GPKG+ G PG PGE G++G RG       PG  G PG  GP G KG +G
Sbjct: 1723 DRGQEG---PRGPKGDPGLPGAPGERGIEGFRGP------PGPQGDPGVRGPAGEKGDRG 1773

Query: 1723 AKGL 1726
              GL
Sbjct: 1774 PPGL 1777



 Score =  253 bits (647), Expect = 1e-66
 Identities = 155/375 (41%), Positives = 190/375 (50%), Gaps = 40/375 (10%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIA-----GERGAPGPVGEQGTKGCYGTKG 1446
            G  G +G PGPPG  GPPG  G +G  G+ G+      GERG PG  GE G  G  G +G
Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRG 2493

Query: 1447 PKGNRGLNGQEGEVGENGIDGLNGEQGDN----GLPGRKGEKGDEGSQGSPGKRGTPGDR 1502
              G  G  G+ GE G+ G  GL G++GD+    G PG +G KGD G +G    RG  GD+
Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP---RGLDGDK 2550

Query: 1503 GAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGP 1562
            G +G  GDPG    D   +G  G KG  G  G RG  GP G PG      A G  G  G 
Sbjct: 2551 GPRGDNGDPG----DKGSKGEPGDKGSAGLPGLRGLLGPQGQPG------AAGIPGDPGS 2600

Query: 1563 QGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGS 1622
             G  G+PG  G +G +G  GP+G +GE GVKG  G  G KG +G  GP G  G  G  G 
Sbjct: 2601 PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE 2660

Query: 1623 QGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGE 1678
             G  G PG  G  G  G  GP+G +G DG PG     G  G +G  G  GFPG SG  G 
Sbjct: 2661 MGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGS 2720

Query: 1679 IGDPGGPGETGLKGARG-------------KMISA-GLPGEMGSPGEPGPPGRKGVKGAK 1724
             G PG PG  G +G  G             +++ A G+PG  G  GE G PG  G +G K
Sbjct: 2721 AGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEK 2780

Query: 1725 GLASFSTCELIQYVR 1739
            G A+ +  ++  +VR
Sbjct: 2781 GEAALTEDDIRGFVR 2795



 Score =  252 bits (643), Expect = 3e-66
 Identities = 173/471 (36%), Positives = 207/471 (43%), Gaps = 113/471 (23%)

Query: 1391 IGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTK---------GC 1441
            +G  G  G+ G  G  GPPG  G  G  GE G+ G  G  GPVGE+G +         G 
Sbjct: 1627 VGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS 1686

Query: 1442 YGTKGPKGNRGLNG----------------QEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
             G+ GPKG+RG  G                ++GE G+ G +G  G +GD GLPG  GE+G
Sbjct: 1687 PGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746

Query: 1486 DEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVD-----------SSIEGPTGLKGERGRQG 1534
             EG +G PG +G PG RG  G +GD G PG+D           +   GP G  G+ G  G
Sbjct: 1747 IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG 1806

Query: 1535 R---------RGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQG 1585
            R         +G PGP G PG   K    G+ G  G  G  G PG DG +G  G  G  G
Sbjct: 1807 RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASG 1866

Query: 1586 PRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGR-----LGSQGNKGEPGDLGEKGAVGF 1640
              G  G KGE+G  G  GPQGPPG  G  G  G+      G  G KG+ G+ G KG  G 
Sbjct: 1867 REGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGL 1926

Query: 1641 PGPRGLQGNDGS-PGY---------------------------------------GSVGR 1660
            PG RGL+G  GS P                                         G  G 
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE 1986

Query: 1661 KGAKGQE---GFPGESGPKGEIGDP-------------GGPGETGLKGARGKMISAGLPG 1704
            +G  G+E   GFPGE G KG+ GDP             G PG +GL G  GK    GLPG
Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046

Query: 1705 EMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHP 1755
              G  GE G PG +G +G KG       E  +  RD  PG  G P  P  P
Sbjct: 2047 RAGGVGEAGRPGERGERGEKG-------ERGEQGRDGPPGLPGTPGPPGPP 2090



 Score =  250 bits (639), Expect = 1e-65
 Identities = 164/389 (42%), Positives = 186/389 (47%), Gaps = 51/389 (13%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPG-PVGEQGTKGCYGTKGPKGN 1450
            G  G  G+ GPPGK GP GF G  G  G+ G  G +G PG  +GE+G  G  G  G  G 
Sbjct: 1979 GPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038

Query: 1451 RGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAK----- 1505
             G+ G  G  G  G  G  GE+G+ G  G +GE+G +G  G PG  G PG  G K     
Sbjct: 2039 PGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDE 2098

Query: 1506 ---GLRGDPGAPGV--------DSSIEGPTG------LKGERGRQGRRGWPGPPGTPGSR 1548
               GL G+ G PG+         +  +GP G      +KG+RG  G RG  G PG PG R
Sbjct: 2099 PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGER 2158

Query: 1549 R------KTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKG--GVG 1600
                   K    G RG  GP G  G PGP G  G  G  GPQGP G  G  GE G  G G
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRG 2218

Query: 1601 SKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDG--------- 1651
              GP G  G  G  G  G +G QG+ G PG +GE G  G PG  G  G DG         
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPG 2278

Query: 1652 SPGY-GSVGRKGAKGQEGFPGES-----GPKGEIGDPGG-----PGETGLKGARGKMISA 1700
            SPG  G VG KG  G  G PG++     G KGE G PGG      GE G KG RG     
Sbjct: 2279 SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPR 2338

Query: 1701 GLPGEMGSPGEPGPPGRKGVKGAKGLASF 1729
            G  GE G  GEPG PG  G KGA G   F
Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367



 Score =  250 bits (639), Expect = 1e-65
 Identities = 151/369 (40%), Positives = 189/369 (51%), Gaps = 41/369 (11%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G  G+PG PG+ G  G  G +G+ G+ G+ G  G+PGP G  G KG  G  G  G  
Sbjct: 2342 GEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLPGAP 2400

Query: 1452 GLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDP 1511
            G+ G  G+ G  G  G  G  G+ GL G  G +G  G  G PG  G+ G  GA GL+GD 
Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460

Query: 1512 GAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGI--- 1568
            G PGV   + GP G +GE G +G  G PG  G  G      + G RG  G  G+AG+   
Sbjct: 2461 GDPGV--GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518

Query: 1569 ----------PGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPG-------PG 1611
                      PGP G +G +G +GP+G  G+ G +G+ G  G KG +G PG       PG
Sbjct: 2519 KGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPG 2578

Query: 1612 -----------GEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGY----G 1656
                       G AG  G  GS G  G PG  GEKG VGF GPRGL+G  G  G     G
Sbjct: 2579 LRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDG 2638

Query: 1657 SVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPG 1716
              G KG  G  G PG +G KGE+G+PG PG++G  G  G +   G  G+ G  G+PGP G
Sbjct: 2639 EKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI---GPKGDRGFDGQPGPKG 2695

Query: 1717 RKGVKGAKG 1725
             +G KG +G
Sbjct: 2696 DQGEKGERG 2704



 Score =  247 bits (631), Expect = 8e-65
 Identities = 156/385 (40%), Positives = 186/385 (48%), Gaps = 64/385 (16%)

Query: 1392 GGDGTMGDPGPPGK--RGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKG 1449
            G  G  G+ GPPG    G PG KG  G  G  G+ G  G PG  G  G KG  G  GP G
Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625

Query: 1450 NRGLNGQEGEVGENG---------IDGLNGEQGDNGLPGRKG---EKGDEGSQGSPGKRG 1497
              G  G++GEVGE G         + G  GE+G  G PG +G   EKGD+G  G  G+ G
Sbjct: 1626 PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNG 1685

Query: 1498 TPGDRGAKGLRGDPGAPGVDSSI---------EGPTGLKGERGRQGRRGWPGPPGTPGSR 1548
            +PG  G KG RG+PG PG    +         +G  G +G+ G +G +G PG PG PG R
Sbjct: 1686 SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGER 1745

Query: 1549 RKTAAHGRRGHTGPQGTAGIPGP---------------DGLEGSLGLKGPQGPRGEAGVK 1593
                  G RG  GPQG  G+ GP                GL+G  G  GP GP G AG  
Sbjct: 1746 ---GIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA 1802

Query: 1594 GE---------KGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPR 1644
            G+         +G  G  GP GPPG  G+ G  G+ G  G  GEPGD GE G  G  G  
Sbjct: 1803 GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS 1862

Query: 1645 GLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISA 1700
            G  G +G  G     G+ G  G +G  G PG  GP G+ G PG PG TG KG R      
Sbjct: 1863 GASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDR------ 1915

Query: 1701 GLPGEMGSPGEPGPPGRKGVKGAKG 1725
               GE GS GE G PG +G++G  G
Sbjct: 1916 ---GETGSKGEQGLPGERGLRGEPG 1937



 Score =  246 bits (629), Expect = 1e-64
 Identities = 157/402 (39%), Positives = 194/402 (48%), Gaps = 65/402 (16%)

Query: 1391 IGGDGTMGDPGPPGKRGP------PGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGT 1444
            +G  G+ G PGPPG +G       PG  G  G+ G+ G  GE G PGP GE+G  G  G 
Sbjct: 2373 VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432

Query: 1445 KGPKGNRGLNGQEGEVGENGIDGLNGEQGDNG--LPGRKGEKGDEGSQG----------- 1491
            +G  G  G  G  G VG  G  GL G++GD G  LPG +GE+G+ G +G           
Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 1492 -------SPGKRGTPGDRGAKGLRGDPGAPGV------------DSSIEGPTGLKGERGR 1532
                   S G+RG  GD G+ GL+GD G   V            D    GP GL G++G 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552

Query: 1533 QGRRGWPGPPGT---PGSRRKTAAHGRRGHTGPQGTA---------------GIPGPDGL 1574
            +G  G PG  G+   PG +      G RG  GPQG                 G+PG  G 
Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE 2612

Query: 1575 EGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE 1634
            +G +G  GP+G +GE GVKG  G  G KG +G  GP G  G  G  G  G  G PG  G 
Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA 2672

Query: 1635 KGAVGFPGPRGLQGNDGSPG----YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGL 1690
             G  G  GP+G +G DG PG     G  G +G  G  GFPG SG  G  G PG PG  G 
Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732

Query: 1691 K---GARGKMISAGLPGE--MGSPGEPGPPGRKGVKGAKGLA 1727
            +   G +G+    G PGE  +G+PG PG PG +G +G  G A
Sbjct: 2733 RGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774



 Score =  242 bits (618), Expect = 3e-63
 Identities = 157/375 (41%), Positives = 181/375 (48%), Gaps = 46/375 (12%)

Query: 1395 GTMGDPGPPG---KRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNR 1451
            G  G PGP G   + G PG  G  G  G  G AG  G  G  GE+G +G  G  GP G  
Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP 2081

Query: 1452 GLNGQEGEVGEN-GID----GLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTP---GDRG 1503
            G  G  G  G    +D    GL+GEQG  GL G KGE G  G QG  G RG P   GDRG
Sbjct: 2082 GTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG 2141

Query: 1504 AKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQ 1563
              G RG  G PG+     G  G +G+ G QG RG PGP G  G      A G  G  GPQ
Sbjct: 2142 EPGPRGQDGNPGLPGE-RGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 1564 GTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQ 1623
            G +G+ G  G  G  G +G  GP G  G+ G  G  G  GPQG PG  G+ G  G+ G+ 
Sbjct: 2201 GPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP 2259

Query: 1624 GNKGEPGDLGEKGAVGFP---------GPRGLQGNDGSPGYGSVGRKGAKGQEGFP---- 1670
            G  G  G  G++G+ G P         GP+G  G  G+PG   VG  GAKG++G P    
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 1671 -------------------GESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGE 1711
                               GE G  G  G+PG PGE G KGA G     G PG +G PG 
Sbjct: 2320 GDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGS 2378

Query: 1712 PGPPGRKGVKGAKGL 1726
            PGPPG  GVKG  GL
Sbjct: 2379 PGPPGPPGVKGDLGL 2393



 Score =  241 bits (614), Expect = 8e-63
 Identities = 169/449 (37%), Positives = 195/449 (43%), Gaps = 115/449 (25%)

Query: 1392 GGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGN- 1450
            G +G  GDPG  G++G  G  G+ G  G +G  GERGAPG +G QG  G  G  GP G  
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901

Query: 1451 -------RGLNGQEGEVGENGIDGLNGEQGDNGLPG------------------------ 1479
                    G  G  GE G  G  GL GE+G  G PG                        
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVE 1961

Query: 1480 ---------------RKGEKGDEGSQGSPGKRGT---PGDRGAKGLRGDPGAPGV----- 1516
                           R+G KGD G QG PGK G    PG+RG KG RGDPG  G      
Sbjct: 1962 TWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLAL 2021

Query: 1517 -DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLE 1575
             +    GP+GL GE G+ G  G PG  G  G   +    G RG  G +G  G  GP GL 
Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP 2081

Query: 1576 GSLGLKGPQGPR--------------GEAGVKGEKGGVGSKGPQGP-------------- 1607
            G+ G  GP GP+              G  G+KG KG  GS G QGP              
Sbjct: 2082 GTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG 2141

Query: 1608 -PGPGGEAGN------------QGRLGSQGNKGEPG------DLGEKGAVGFPGPRGLQG 1648
             PGP G+ GN            +G+ G QG +G PG      D G  GA G  GP G QG
Sbjct: 2142 EPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQG 2201

Query: 1649 ---------NDGSPGYGSVGRKGAKGQEGFPGESG---PKGEIGDPGGPGETGLKGARGK 1696
                       G PG G  G  GA G  G PG SG   P+G  G PG  GETG  GA G+
Sbjct: 2202 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR 2261

Query: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
              ++G  G+ GSPG PG PG  G  G KG
Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKG 2290



 Score =  233 bits (593), Expect = 2e-60
 Identities = 148/331 (44%), Positives = 171/331 (51%), Gaps = 28/331 (8%)

Query: 1415 EGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGD 1474
            +G  GE G  G RG  GP G+ G  G  G  GP+G  G    +GE G  G DG  G  G 
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR 1312

Query: 1475 NGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG 1534
             G PG  G  G +GS G PG RG PG+RG +G +G+PGAPG     EGP GL G +G  G
Sbjct: 1313 AGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP-GLPGRKGDPG 1371

Query: 1535 RRGWP------------GPPGTPGSRRK--TAAHGRRGHTGPQGTAGI-PGPDGLEGSLG 1579
              G P            GPPG PG+  K      G RG  GP G  GI PG  GL G  G
Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP-GEGGIAPGEPGLPGLPG 1430

Query: 1580 LKGPQGPRGEAGVKGEK-----GGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGE 1634
              GPQGP G  G KGEK     G  G  G  G PG  G  G  G +G +G++G PG LGE
Sbjct: 1431 SPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGE 1490

Query: 1635 KGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGAR 1694
             G  G  GP G  G+ G PG    GR GAKG EG PG +G +GE G+PG PG+  + G  
Sbjct: 1491 AGEKGERGPPGPAGSRGLPGV--AGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP- 1547

Query: 1695 GKMISAGLPGEMGSPGEPGPPGRKGVKGAKG 1725
                 AG  GE G  G  GP G  GV+G +G
Sbjct: 1548 ---AVAGPKGEKGDVGPAGPRGATGVQGERG 1575



 Score =  177 bits (450), Expect = 8e-44
 Identities = 130/310 (41%), Positives = 151/310 (48%), Gaps = 44/310 (14%)

Query: 1455 GQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAP 1514
            GQ+GE GE G+ G  G  GD GLPGR G         +PG +G PG   AKG RG PGA 
Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGLPGRTG---------APGPQGPPGSATAKGERGFPGA- 1303

Query: 1515 GVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD-G 1573
                  +G  G  G  G  G  G PG  G+PG        G RG  GP+G  G PG   G
Sbjct: 1304 ------DGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 1574 LEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLG 1633
             EG  GL G +G  G +G  G +G +G  GP+GPPG  G A  +G  G +G +G PG  G
Sbjct: 1358 GEGP-GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTA-MKGDKGDRGERGPPGP-G 1414

Query: 1634 EKGAVGFPGPRGLQGNDGSPG-YGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKG 1692
            E G    PG  GL G  GSPG  G VG  G KG++G   E G  G  G PG PGE G +G
Sbjct: 1415 EGGIA--PGEPGLPGLPGSPGPQGPVGPPGKKGEKG-DSEDGAPGLPGQPGSPGEQGPRG 1471

Query: 1693 ---ARGKMISAGLPGEMGSPGEP---GPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRH 1746
               A G     G PG +G  GE    GPPG  G +G  G+A               PG  
Sbjct: 1472 PPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAG-------------RPGAK 1518

Query: 1747 GKPECPVHPT 1756
            G PE P  PT
Sbjct: 1519 G-PEGPPGPT 1527



 Score =  152 bits (385), Expect = 3e-36
 Identities = 104/264 (39%), Positives = 124/264 (46%), Gaps = 47/264 (17%)

Query: 1481 KGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPG 1540
            KG+KG+ G  G  G+ G PGD G  G  G PG          P G  G    +G RG+PG
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPG----------PQGPPGSATAKGERGFPG 1302

Query: 1541 PPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVG 1600
              G PGS             G  G  G PG  GL+GS GL GP+G  GE G         
Sbjct: 1303 ADGRPGS------------PGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG--------- 1341

Query: 1601 SKGPQGPPG-PGGEAGNQGRLGSQGNKGEPGDL---GEKGAVGFPGPRGLQGNDGSPGYG 1656
             +GP+G PG PG   G +G  G  G KG+PG     G +G +G PGPRG  G  G+   G
Sbjct: 1342 PRGPKGEPGAPGQVIGGEGP-GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKG 1400

Query: 1657 SVGRKGAKGQEG------FPGESGPKGEIGDPGGPGETGLKGARGKMISA-----GLPGE 1705
              G +G +G  G       PGE G  G  G PG  G  G  G +G+   +     GLPG+
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ 1460

Query: 1706 MGSPGEPGPPGRKGVKGAKGLASF 1729
             GSPGE GP G  G  G KG   F
Sbjct: 1461 PGSPGEQGPRGPPGAIGPKGDRGF 1484



 Score =  117 bits (292), Expect = 2e-25
 Identities = 64/165 (38%), Positives = 82/165 (49%), Gaps = 14/165 (8%)

Query: 1388 CKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGP 1447
            C   G  G  G+ GPPG+   PG  G +G +GE G+ G+ GAPG           G  GP
Sbjct: 2634 CGLDGEKGDKGEAGPPGR---PGLAGHKGEMGEPGVPGQSGAPGK---------EGLIGP 2681

Query: 1448 KGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507
            KG+RG +GQ G  G+ G  G  G  G  G PG  G  G  G  G PG  G  G  G +G 
Sbjct: 2682 KGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQ 2741

Query: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTA 1552
            +G+ G PG    + G  G+ G  G +G +G PGP G  G + + A
Sbjct: 2742 KGERGPPG--ERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAA 2784



 Score =  105 bits (262), Expect = 5e-22
 Identities = 69/197 (35%), Positives = 106/197 (53%), Gaps = 10/197 (5%)

Query: 799 REECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK--KADVGKNQVRFGALKYADD 856
           R  C R+   D+VF++D S SI    +  ++ F+ GLV           VRF  ++Y+DD
Sbjct: 28  RVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDD 87

Query: 857 PEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEA-LGFSDHMFTEARGSRLNKGVPQVL 915
           P   F LD  G+  +VI  ++     GG+T T  A L  +DH+F          GVP+V 
Sbjct: 88  PRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLP---QLARPGVPKVC 144

Query: 916 IVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAG--SSDKYFFVETFG 973
           I+ITDG+S D   ++  A+ L+ +G+ + AVGI  A+P EL  +A   +SD +FFV  F 
Sbjct: 145 ILITDGKSQDL--VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFS 202

Query: 974 GLKGIFSDVTASVCNSS 990
            L+ +   V+  VC ++
Sbjct: 203 ILRTLLPLVSRRVCTTA 219



 Score =  105 bits (261), Expect = 7e-22
 Identities = 59/171 (34%), Positives = 103/171 (60%), Gaps = 4/171 (2%)

Query: 621 ADIMFLVDSSGSIGPENFSKMKTFMKNLVS--KSQIGPDRVQIGVVQFSDINKEEFQLNR 678
           ADI+FL+D S SIG  NF ++++F++ LV           V+   VQ+SD  + EF L+ 
Sbjct: 37  ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 679 FMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIV 738
             S  D+  AI ++++ G  T TG+A+  V+ +    + ARP + K  ILITDG++QD+V
Sbjct: 97  LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCILITDGKSQDLV 156

Query: 739 KEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMVFYVENFDILQRI 787
              A  L+ +GV +++VG+  ++  +L+ ++ +P  +  F+V +F IL+ +
Sbjct: 157 DTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTL 207



 Score =  104 bits (259), Expect = 1e-21
 Identities = 63/186 (33%), Positives = 105/186 (56%), Gaps = 8/186 (4%)

Query: 1000 DLVFLMDGSTSIQPNDFKKMKEFLASVVQDFD--VSLNRVRIGAAQFSDTYHPEFPLGTF 1057
            D+VFL+DGS+SI  ++F++++ FL  +V  F    S   VR    Q+SD    EF L   
Sbjct: 38   DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 1058 IGEKEISFQIENIKQIFGNTHIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQD 1116
                ++   I  +    GNT  GAA+  V +H F P +      G P+V +++TDG+SQD
Sbjct: 98   GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQD 154

Query: 1117 EVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITG--TAEKKLTVHNFDELKKVNKRIVRN 1174
             V  AA+ L+ +G+ +++VGI + D ++L ++    T++    V++F  L+ +   + R 
Sbjct: 155  LVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRR 214

Query: 1175 ICTTAG 1180
            +CTTAG
Sbjct: 215  VCTTAG 220



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 59/188 (31%), Positives = 102/188 (54%), Gaps = 5/188 (2%)

Query: 429 CVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHK--VRVGAVQYADSWDL 486
           C     ADI  L+DGS S   ++F E+++FL  +V  F+ A     VR   VQY+D    
Sbjct: 31  CTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRT 90

Query: 487 EFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTN 546
           EF ++   +  D+ +AI  +   GGNT TGAA+      +   +  R   VP   +++T+
Sbjct: 91  EFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPG-VPKVCILITD 149

Query: 547 GMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKR--VYYVHDFDALKDIRN 604
           G S+D +   A RL+ + ++++A+GIK A+  +L+ +A +      ++V+DF  L+ +  
Sbjct: 150 GKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLP 209

Query: 605 QVVQEICT 612
            V + +CT
Sbjct: 210 LVSRRVCT 217



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 54/171 (31%), Positives = 88/171 (51%), Gaps = 5/171 (2%)

Query: 228 ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENC--MRVGLVAYSNETKVINSLSM 285
           AD+VFLLD S +    NF  ++ FLE  V       +   +R   V YS++ +    L  
Sbjct: 37  ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 286 GINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSE 345
             +  +V++ I+ LS + G   TGAAI  +   VF  +       GVP++ +L+T   S+
Sbjct: 97  LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQ 153

Query: 346 DNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADL 396
           D V  AA  L+ +GV +F +GI+ A   +L+++AS P   +   +  F+ L
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSIL 204



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 50/165 (30%), Positives = 83/165 (50%), Gaps = 11/165 (6%)

Query: 26  ADVVFLVDSSDRLGSKSFPFVKMFITKMIS--SLPIEADKYRVALAQYSDKLHSEFHLST 83
           AD+VFL+D S  +G  +F  V+ F+  ++   S    A   R A  QYSD   +EF L  
Sbjct: 37  ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 84  FKGRSPMLNHLRKNFGFIGGSLQIGKA-LQEAHRTYFSAPANGRDKKQFPPILVVLASSE 142
                 ++  +R+   + GG+ + G A L  A   +    A    +   P + +++   +
Sbjct: 97  LGSGGDVIRAIRE-LSYKGGNTRTGAAILHVADHVFLPQLA----RPGVPKVCILITDGK 151

Query: 143 SEDNVEEASKALRKDGVKIISVGVQKASEENLKAMA---TSQFHF 184
           S+D V+ A++ L+  GVK+ +VG++ A  E LK +A   TS F F
Sbjct: 152 SQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFF 196



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 25/175 (14%)

Query: 1965 DAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNT 2024
            D  FLLD S ++G + F ++R+FL  L+  F        S  G R A + ++        
Sbjct: 38   DIVFLLDGSSSIGRSNFREVRSFLEGLVLPF----SGAASAQGVRFATVQYS-------- 85

Query: 2025 QKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRR--- 2081
                 R EF L    S   + R + E +    G+   G A+    D+VFL  P L R   
Sbjct: 86   --DDPRTEFGLDALGSGGDVIRAIRE-LSYKGGNTRTGAAILHVADHVFL--PQLARPGV 140

Query: 2082 NKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136
             KV  +I+ G++     +++   + R K QG  LF   +    D +EL+ +AS P
Sbjct: 141  PKVCILITDGKSQ----DLVDTAAQRLKGQGVKLFAVGIKNA-DPEELKRVASQP 190



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 41/222 (18%), Positives = 88/222 (39%), Gaps = 6/222 (2%)

Query: 581  REIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSK 640
            + + G E  V Y+     + D        +     C    AD++FL  ++        + 
Sbjct: 1013 QRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEAT 1072

Query: 641  MKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQT-T 699
             +   + +++   +GP  VQ+G++ +S      F LN       I   I  M ++  +  
Sbjct: 1073 RRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGN 1132

Query: 700  LTGSALSFVSQYF--SPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGV 757
              G+A+    +Y       G R ++   ++L+ D   +  +  P    +  G+ +  +G+
Sbjct: 1133 NLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGM 1192

Query: 758  FGSNVTQLEEISGRPEMV---FYVENFDILQRIEDDLVFGIC 796
             G++  QL  ++   + V   F V++   L +    L   +C
Sbjct: 1193 AGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALC 1234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,165,975
Number of Sequences: 37866
Number of extensions: 4760889
Number of successful extensions: 113269
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 244
Number of HSP's successfully gapped in prelim test: 595
Number of HSP's that attempted gapping in prelim test: 16983
Number of HSP's gapped (non-prelim): 8581
length of query: 2263
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2145
effective length of database: 13,779,330
effective search space: 29556662850
effective search space used: 29556662850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.