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Search of human proteins with 15529990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15529990 granzyme H [Homo sapiens]
(246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15529990 granzyme H [Homo sapiens] 507 e-144
gi|221625528 granzyme B precursor [Homo sapiens] 351 3e-97
gi|4503149 cathepsin G preproprotein [Homo sapiens] 289 2e-78
gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens] 226 1e-59
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 169 2e-42
gi|5453676 granzyme A precursor [Homo sapiens] 166 2e-41
gi|4504235 granzyme K precursor [Homo sapiens] 156 1e-38
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 154 7e-38
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 153 1e-37
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 153 1e-37
gi|42544239 complement factor D preproprotein [Homo sapiens] 153 2e-37
gi|71361688 myeloblastin [Homo sapiens] 150 1e-36
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 147 6e-36
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 147 6e-36
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 147 6e-36
gi|47551347 protease, serine-like 1 [Homo sapiens] 142 2e-34
gi|4885369 granzyme M precursor [Homo sapiens] 139 2e-33
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 138 4e-33
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 135 4e-32
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 135 4e-32
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 134 6e-32
gi|11496281 kallikrein 13 precursor [Homo sapiens] 134 7e-32
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 133 2e-31
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 131 6e-31
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 130 8e-31
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 129 3e-30
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 126 2e-29
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 126 2e-29
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 125 3e-29
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 124 1e-28
>gi|15529990 granzyme H [Homo sapiens]
Length = 246
Score = 507 bits (1305), Expect = e-144
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60
MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL
Sbjct: 1 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60
Query: 61 TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW
Sbjct: 61 TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNY 180
TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNY
Sbjct: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNY 180
Query: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIK 240
SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIK
Sbjct: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIK 240
Query: 241 RTMKRL 246
RTMKRL
Sbjct: 241 RTMKRL 246
>gi|221625528 granzyme B precursor [Homo sapiens]
Length = 247
Score = 351 bits (901), Expect = 3e-97
Identities = 176/246 (71%), Positives = 194/246 (78%), Gaps = 1/246 (0%)
Query: 1 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60
MQP LLLLAFLL P A EIIGGHEAKPHSRPYMA++ +KS KRCGG L+R DFVL
Sbjct: 1 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL 60
Query: 61 TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
TAAHC GSSINVTLGAHNIKEQE TQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK
Sbjct: 61 TAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR 120
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGN 179
T AV+PLRLPS+KAQVKPGQ CSVAGWG + + + TLQEV +TVQ+D +CE
Sbjct: 121 TRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY 180
Query: 180 YSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWI 239
Y E+CVGDP+ +T FKGDSGGPLVC VAQGI+SYG G PP KVS F+ WI
Sbjct: 181 YDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWI 240
Query: 240 KRTMKR 245
K+TMKR
Sbjct: 241 KKTMKR 246
>gi|4503149 cathepsin G preproprotein [Homo sapiens]
Length = 255
Score = 289 bits (739), Expect = 2e-78
Identities = 141/244 (57%), Positives = 175/244 (71%), Gaps = 1/244 (0%)
Query: 1 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60
MQP LLLLAFLL GA EIIGG E++PHSRPYMA++Q + RCGG LVR+DFVL
Sbjct: 1 MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL 60
Query: 61 TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
TAAHC GS+INVTLGAHNI+ +E TQQ I +R I HP YN + NDIMLLQL R+ +
Sbjct: 61 TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR 120
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNY 180
V P+ LP ++ ++PG LC+VAGWG VSM TL+EV L VQ+D QC R+F G+Y
Sbjct: 121 NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIF-GSY 179
Query: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIK 240
+ICVGD ++ + FKGDSGGPL+C +VA GI+SYG G PP V+ +VS FLPWI+
Sbjct: 180 DPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIR 239
Query: 241 RTMK 244
TM+
Sbjct: 240 TTMR 243
>gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens]
Length = 247
Score = 226 bits (577), Expect = 1e-59
Identities = 118/242 (48%), Positives = 153/242 (63%), Gaps = 4/242 (1%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKS-RKRCGGILVRKDFVLTAA 63
L LL FLL A EIIGG E KPHSRPYMA+++ + K CGG L+R++FVLTAA
Sbjct: 6 LPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAA 65
Query: 64 HCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTA 123
HC G SI VTLGAHNI E+E T Q + V + HP YN +DIMLL+L+ KA T A
Sbjct: 66 HCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLA 125
Query: 124 VRPLRLPSSKAQVKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSR 182
V L PS V PG++C VAGWG + + TLQEV L + C ++
Sbjct: 126 VGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF--RDFDH 183
Query: 183 ATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRT 242
++CVG+P+KT++ FKGDSGGPL+C VAQGI+SYG PP V+ ++SH+ PWI +
Sbjct: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQI 243
Query: 243 MK 244
++
Sbjct: 244 LQ 245
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 169 bits (429), Expect = 2e-42
Identities = 98/258 (37%), Positives = 142/258 (55%), Gaps = 23/258 (8%)
Query: 5 LLLLAFLLTPGAGTE--EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTA 62
LL L+FLL A + +++ G E PHS+P+ L E+ R CG L+ +VL+A
Sbjct: 4 LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVA---LYERGRFNCGASLISPHWVLSA 60
Query: 63 AHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTT 122
AHCQ + V LG HN+++++ +Q R IPHP Y ++ NDIMLL+L + A+
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
Query: 123 AVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS------------TLATTLQEVLLTVQKDC 170
VRP LP+ PG+ C V+GWG VS + +L TL +++ D
Sbjct: 121 QVRPAVLPTRCPH--PGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
Query: 171 QCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN---KKGTPPG 227
C++ + G + T +C G + +GDSGGPLVC + QGI+S+G+ T PG
Sbjct: 179 SCDKSYPGRLTN-TMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
Query: 228 VYIKVSHFLPWIKRTMKR 245
VY KV H+L WI+ TMKR
Sbjct: 238 VYTKVCHYLEWIRETMKR 255
>gi|5453676 granzyme A precursor [Homo sapiens]
Length = 262
Score = 166 bits (420), Expect = 2e-41
Identities = 103/250 (41%), Positives = 140/250 (56%), Gaps = 15/250 (6%)
Query: 6 LLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKR-CGGILVRKDFVLTAAH 64
++++ LL P E+IIGG+E PHSRPYM + RK C G L+ KD+VLTAAH
Sbjct: 14 VVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAH 69
Query: 65 CQ-GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTA 123
C V LGAH+I +E T+Q + VK+ P+P Y+P D+ LLQL KAK
Sbjct: 70 CNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKY 129
Query: 124 VRPLRLPSSKAQVKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSR 182
V L LP VKPG +C VAGWG + ++ + TL+EV +T+ C H N++
Sbjct: 130 VTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP 189
Query: 183 A---TEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG--NKKGTP--PGVYIKVS-H 234
+C G + + GDSG PL+C+ V +G+ S+G NK G P PGVYI +S
Sbjct: 190 VIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKK 249
Query: 235 FLPWIKRTMK 244
L WI T+K
Sbjct: 250 HLNWIIMTIK 259
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 156 bits (395), Expect = 1e-38
Identities = 96/253 (37%), Positives = 140/253 (55%), Gaps = 17/253 (6%)
Query: 4 FLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAA 63
F L++ +T EIIGG E PHSRP+MA +Q+ CGG+L+ +VLTAA
Sbjct: 10 FFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAA 66
Query: 64 HCQ-----GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118
HCQ G S V LGAH++ + E ++Q + +K+ IP SNDIML++L+ A
Sbjct: 67 HCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAA 126
Query: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTV--QKDCQCER 174
K V+ L + SK ++ G C V GWG +L + TL+EV +TV +K C +
Sbjct: 127 KLNKHVKMLHI-RSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQS 185
Query: 175 LFHGN-YSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKG--TPPGVY-I 230
++G+ + +C GD K + KGDSGGPL+CK V I+S G++ G T PG+Y +
Sbjct: 186 YYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTL 245
Query: 231 KVSHFLPWIKRTM 243
+ WIK +
Sbjct: 246 LTKKYQTWIKSNL 258
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 154 bits (389), Expect = 7e-38
Identities = 94/248 (37%), Positives = 140/248 (56%), Gaps = 17/248 (6%)
Query: 4 FLLLL--AFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLT 61
FLLLL A+ A ++++GGHE +PHS+P+ A L + + CGG+LV ++VLT
Sbjct: 14 FLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAA---LFQGQQLLCGGVLVGGNWVLT 70
Query: 62 AAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNP---KNFSNDIMLLQLERKA 118
AAHC+ V LG H+++ ++ +Q IPV + IPHP YN ++ ++D+MLLQL +A
Sbjct: 71 AAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQA 130
Query: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVS--MSTLATTLQEVLLTVQKDCQCERLF 176
+ V+P+ L Q PGQ C+V+GWG V+ TL + + +CE +
Sbjct: 131 SLGSKVKPISLADHCTQ--PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAY 188
Query: 177 HGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVS 233
G + +C G K T +GDSGGPLVC QGI S+G+ + PGVY +
Sbjct: 189 PGQITDGM-VCAGSSKGADT-CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNIC 246
Query: 234 HFLPWIKR 241
+L WIK+
Sbjct: 247 RYLDWIKK 254
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 153 bits (387), Expect = 1e-37
Identities = 90/246 (36%), Positives = 139/246 (56%), Gaps = 10/246 (4%)
Query: 5 LLLLAFLLTPGAGTE-EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAA 63
L +LA +T E +IIGGH S+P+ A + + R CGG L+ +V+TAA
Sbjct: 24 LQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAAL-LAGPRRRFLCGGALLSGQWVITAA 82
Query: 64 HCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTA 123
HC + V LG HN++ E TQQ + V R + HP YN + ND+MLLQL++ A+ A
Sbjct: 83 HCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRA 142
Query: 124 VRPLRLPSSKAQVKPGQLCSVAGWGYVS--MSTLATTLQEVLLTVQKDCQCERLFHGNYS 181
VRP+ + ++A PG C V+GWG +S ++ +LQ V + + D C++ + +
Sbjct: 143 VRPIEV--TQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTIT 200
Query: 182 RATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK-GTP--PGVYIKVSHFLPW 238
+C G P+ + +GDSGGPLVC+ QG++S+G ++ P PGVY + + W
Sbjct: 201 PGM-VCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259
Query: 239 IKRTMK 244
I+ TM+
Sbjct: 260 IEETMR 265
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 153 bits (387), Expect = 1e-37
Identities = 91/243 (37%), Positives = 136/243 (55%), Gaps = 20/243 (8%)
Query: 12 LTPGAG-----TEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQ 66
L P AG ++++GGHE +PHS+P+ A L + + CGG+LV ++VLTAAHC+
Sbjct: 64 LPPAAGHSRAQEDKVLGGHECQPHSQPWQAA---LFQGQQLLCGGVLVGGNWVLTAAHCK 120
Query: 67 GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNP---KNFSNDIMLLQLERKAKWTTA 123
V LG H+++ ++ +Q IPV + IPHP YN ++ ++D+MLLQL +A +
Sbjct: 121 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 180
Query: 124 VRPLRLPSSKAQVKPGQLCSVAGWGYVS--MSTLATTLQEVLLTVQKDCQCERLFHGNYS 181
V+P+ L Q PGQ C+V+GWG V+ TL + + +CE + G +
Sbjct: 181 VKPISLADHCTQ--PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQIT 238
Query: 182 RATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPW 238
+C G K T +GDSGGPLVC QGI S+G+ + PGVY + +L W
Sbjct: 239 DGM-VCAGSSKGADT-CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDW 296
Query: 239 IKR 241
IK+
Sbjct: 297 IKK 299
>gi|42544239 complement factor D preproprotein [Homo sapiens]
Length = 253
Score = 153 bits (386), Expect = 2e-37
Identities = 92/243 (37%), Positives = 126/243 (51%), Gaps = 12/243 (4%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
L+LL I+GG EA+ H+RPYMA VQ CGG+LV + +VL+AAH
Sbjct: 10 LVLLGAAACAAPPRGRILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAAH 66
Query: 65 C----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
C + V LGAH++ + E +++ V R +PHP P +D++LLQL KA
Sbjct: 67 CLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATL 126
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGN 179
AVRPL V PG LC VAGWG V+ +LQ VLL V C R H +
Sbjct: 127 GPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHD 186
Query: 180 YSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFL 236
TE + + KGDSGGPLVC V +G+++ G++ PG+Y +V+ +
Sbjct: 187 -GAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYA 245
Query: 237 PWI 239
WI
Sbjct: 246 AWI 248
>gi|71361688 myeloblastin [Homo sapiens]
Length = 256
Score = 150 bits (379), Expect = 1e-36
Identities = 94/249 (37%), Positives = 132/249 (53%), Gaps = 19/249 (7%)
Query: 6 LLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC 65
+LLA LL+ A EI+GGHEA+PHSRPYMA +Q CGG L+ FVLTAAHC
Sbjct: 13 VLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC 72
Query: 66 ----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWT 121
+NV LGAHN++ QE TQQ V + + Y+ +N ND++L+QL A +
Sbjct: 73 LRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131
Query: 122 TAVRPLRLPSSKAQVKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNY 180
+V ++LP V G C GWG V + A LQE+ +TV +
Sbjct: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FF 181
Query: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSY---GNKKGTPPGVYIKVSHFLP 237
R IC P++ GDSGGPL+C + QGI S+ G P + +V+ ++
Sbjct: 182 CRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241
Query: 238 WIKRTMKRL 246
WI+ T++R+
Sbjct: 242 WIRSTLRRV 250
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 147 bits (372), Expect = 6e-36
Identities = 95/249 (38%), Positives = 130/249 (52%), Gaps = 15/249 (6%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
L+LLA G II G E KPHS+P+ A L EK+R CG L+ ++LTAAH
Sbjct: 6 LILLALATGLVGGETRIIKGFECKPHSQPWQAA---LFEKTRLLCGATLIAPRWLLTAAH 62
Query: 65 CQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYN----PKNFSNDIMLLQLERKAKW 120
C V LG HN++++E +Q PHP +N K+ NDIML+++
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHG 178
T AVRPL L S V G C ++GWG S L TL+ +T+ + +CE + G
Sbjct: 123 TWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 179 NYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK---GTPPGVYIKVSHF 235
N + T +C + + +GDSGGPLVC QGI+S+G PGVY KV +
Sbjct: 181 NIT-DTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKY 239
Query: 236 LPWIKRTMK 244
+ WI+ TMK
Sbjct: 240 VDWIQETMK 248
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 147 bits (372), Expect = 6e-36
Identities = 95/249 (38%), Positives = 130/249 (52%), Gaps = 15/249 (6%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
L+LLA G II G E KPHS+P+ A L EK+R CG L+ ++LTAAH
Sbjct: 38 LILLALATGLVGGETRIIKGFECKPHSQPWQAA---LFEKTRLLCGATLIAPRWLLTAAH 94
Query: 65 CQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYN----PKNFSNDIMLLQLERKAKW 120
C V LG HN++++E +Q PHP +N K+ NDIML+++
Sbjct: 95 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHG 178
T AVRPL L S V G C ++GWG S L TL+ +T+ + +CE + G
Sbjct: 155 TWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
Query: 179 NYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK---GTPPGVYIKVSHF 235
N + T +C + + +GDSGGPLVC QGI+S+G PGVY KV +
Sbjct: 213 NIT-DTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKY 271
Query: 236 LPWIKRTMK 244
+ WI+ TMK
Sbjct: 272 VDWIQETMK 280
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 147 bits (372), Expect = 6e-36
Identities = 95/249 (38%), Positives = 130/249 (52%), Gaps = 15/249 (6%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
L+LLA G II G E KPHS+P+ A L EK+R CG L+ ++LTAAH
Sbjct: 6 LILLALATGLVGGETRIIKGFECKPHSQPWQAA---LFEKTRLLCGATLIAPRWLLTAAH 62
Query: 65 CQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYN----PKNFSNDIMLLQLERKAKW 120
C V LG HN++++E +Q PHP +N K+ NDIML+++
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHG 178
T AVRPL L S V G C ++GWG S L TL+ +T+ + +CE + G
Sbjct: 123 TWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 179 NYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK---GTPPGVYIKVSHF 235
N + T +C + + +GDSGGPLVC QGI+S+G PGVY KV +
Sbjct: 181 NIT-DTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKY 239
Query: 236 LPWIKRTMK 244
+ WI+ TMK
Sbjct: 240 VDWIQETMK 248
>gi|47551347 protease, serine-like 1 [Homo sapiens]
Length = 283
Score = 142 bits (359), Expect = 2e-34
Identities = 100/259 (38%), Positives = 135/259 (52%), Gaps = 19/259 (7%)
Query: 2 QPFLLLLAFLLTP-----GAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRK 56
+P L + L+ P G+ +IIGGHE PHSRPYMA V+F + CGG L+R
Sbjct: 10 RPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRA 66
Query: 57 DFVLTAAHCQGS----SINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLL 112
+V++AAHC + V LGAH + E TQQ + HP Y+P +NDI LL
Sbjct: 67 RWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLL 126
Query: 113 QLERKAKWTTAVRPLRLPSSKAQ-VKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDC 170
+L A AV LRLP +A+ G C VAGWG+VS L L E + V
Sbjct: 127 RLNGSAVLGPAVGLLRLPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPD 186
Query: 171 QCERLFHGNYSRATEICVGDPKKTQTGF-KGDSGGPLVCKDVAQGILSY-GNKKGTP--P 226
C + G+ + T +C + GF DSGGPLVC++ A G++S+ G G P P
Sbjct: 187 VCNSSWKGHLT-LTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTP 245
Query: 227 GVYIKVSHFLPWIKRTMKR 245
VY +VS F+ WI ++R
Sbjct: 246 DVYTQVSAFVAWIWDVVRR 264
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 139 bits (351), Expect = 2e-33
Identities = 95/253 (37%), Positives = 130/253 (51%), Gaps = 19/253 (7%)
Query: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
+L L L + +IIGG E PHSRPYMA LQ CGG+LV +VLTAAH
Sbjct: 10 VLALGALSVGSSFGTQIIGGREVIPHSRPYMAS---LQRNGSHLCGGVLVHPKWVLTAAH 66
Query: 65 CQG---SSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAKW 120
C + + + LG H + T +K I HP Y P ND+ LLQL+ K K
Sbjct: 67 CLAQRMAQLRLVLGLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKP 123
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSM-STLATTLQEVLLTV--QKDCQCERLFH 177
+ +RPL LPS + V G CS+AGWG L+ L+E+ L V + C R ++
Sbjct: 124 SRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWN 183
Query: 178 GNYSRATEICVGDPKKTQTGFKGDSGGPLVCKD--VAQGILSYGNKKGT---PPGVYIKV 232
G+ S + +C+ K Q KGDSGGPLVC V G+LS+ ++ T P V V
Sbjct: 184 GSLS-PSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAV 242
Query: 233 SHFLPWIKRTMKR 245
+ ++ WI++ R
Sbjct: 243 APYVSWIRKVTGR 255
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 138 bits (348), Expect = 4e-33
Identities = 87/250 (34%), Positives = 130/250 (52%), Gaps = 14/250 (5%)
Query: 1 MQPFLLLL---AFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKD 57
M P L+L A L P ++I+GG+ + +S PY Q CGG L+ +
Sbjct: 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPY----QVSLNSGYHFCGGSLINEQ 56
Query: 58 FVLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERK 117
+V++A HC S I V LG HNI+ E +QFI + I HP Y+ K +NDIML++L +
Sbjct: 57 WVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSR 116
Query: 118 AKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERL 175
A V + LP+ A G C ++GWG + S LQ + V +CE
Sbjct: 117 AVINARVSTISLPT--APPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS 174
Query: 176 FHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN--KKGTPPGVYIKVS 233
+ G + + CVG + + +GDSGGP+VC QG++S+G+ + PGVY KV
Sbjct: 175 YPGKIT-SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVY 233
Query: 234 HFLPWIKRTM 243
+++ WIK T+
Sbjct: 234 NYVKWIKNTI 243
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 135 bits (339), Expect = 4e-32
Identities = 81/245 (33%), Positives = 126/245 (51%), Gaps = 12/245 (4%)
Query: 6 LLLAFLLTPGAGTEE---IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTA 62
L++ L A EE ++ G S PY A L CGG+L+ +VLTA
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAA---LYTSGHLLCGGVLIHPLWVLTA 60
Query: 63 AHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTT 122
AHC+ ++ V LG HN++++E +Q+ V R + HP Y+ + DIMLL+L R AK +
Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 123 AVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSR 182
++P LP + C + GWG + T+Q + + +CE + G ++
Sbjct: 121 LIQP--LPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQ 178
Query: 183 ATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN---KKGTPPGVYIKVSHFLPWI 239
+C GD K + +GDSGGPLVC D +G++S+GN PGVY V + WI
Sbjct: 179 -NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
Query: 240 KRTMK 244
++T++
Sbjct: 238 QKTIQ 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 135 bits (339), Expect = 4e-32
Identities = 81/245 (33%), Positives = 126/245 (51%), Gaps = 12/245 (4%)
Query: 6 LLLAFLLTPGAGTEE---IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTA 62
L++ L A EE ++ G S PY A L CGG+L+ +VLTA
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAA---LYTSGHLLCGGVLIHPLWVLTA 60
Query: 63 AHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTT 122
AHC+ ++ V LG HN++++E +Q+ V R + HP Y+ + DIMLL+L R AK +
Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 123 AVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSR 182
++P LP + C + GWG + T+Q + + +CE + G ++
Sbjct: 121 LIQP--LPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQ 178
Query: 183 ATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN---KKGTPPGVYIKVSHFLPWI 239
+C GD K + +GDSGGPLVC D +G++S+GN PGVY V + WI
Sbjct: 179 -NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
Query: 240 KRTMK 244
++T++
Sbjct: 238 QKTIQ 242
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 134 bits (338), Expect = 6e-32
Identities = 91/264 (34%), Positives = 139/264 (52%), Gaps = 32/264 (12%)
Query: 4 FLLLLAFLLTPGAGT-----EEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDF 58
FL+L L G G I+GG E + HS+P+ A L S +CGGILV + +
Sbjct: 3 FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAA---LYHFSTFQCGGILVHRQW 59
Query: 59 VLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYN-----------PKNFSN 107
VLTAAHC + + LG HN+ + E T QF+ V PHP +N +++S+
Sbjct: 60 VLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSH 119
Query: 108 DIMLLQLERKAKW-TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLA--TTLQEVLL 164
D+MLL+L A T AV+ + LP+ + +V G C +GWG + + LQ V L
Sbjct: 120 DLMLLRLTEPADTITDAVKVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDL 177
Query: 165 TVQKDCQCERLFHGNYSRATE--ICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK 222
+ + +C++ + + T+ +CVG + + GDSGGPL+C V QG+ S+G
Sbjct: 178 KILPNDECKK---AHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVP 234
Query: 223 -GTP--PGVYIKVSHFLPWIKRTM 243
GTP P V ++V ++ WI+ T+
Sbjct: 235 CGTPNKPSVAVRVLSYVKWIEDTI 258
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 134 bits (337), Expect = 7e-32
Identities = 83/232 (35%), Positives = 125/232 (53%), Gaps = 14/232 (6%)
Query: 23 GGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIKEQ 82
GG+ PHS+P+ A L + R CGG+LV +VLTAAHC + V LG H +
Sbjct: 38 GGYTCFPHSQPWQAA---LLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRV 94
Query: 83 ERTQQFIPVKRPIPHPAYNPK----NFSNDIMLLQLERKAKWTTAVRPLRLPSSKAQVKP 138
E +Q V IPHP Y N +DIMLL+L+ + T ++ L L S ++ P
Sbjct: 95 EAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPL-SHNNRLTP 153
Query: 139 GQLCSVAGWGYVSMSTL--ATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQT 196
G C V+GWG + + TLQ + ++ D +C +++ G + +C G + +
Sbjct: 154 GTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKIT-DNMLCAGTKEGGKD 212
Query: 197 GFKGDSGGPLVCKDVAQGILSYGN-KKGTP--PGVYIKVSHFLPWIKRTMKR 245
+GDSGGPLVC GI+S+G+ G P PGVY +VS ++ WI+ T+++
Sbjct: 213 SCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRK 264
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 133 bits (334), Expect = 2e-31
Identities = 89/241 (36%), Positives = 120/241 (49%), Gaps = 26/241 (10%)
Query: 21 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 80
I+GG E + HS+P+ V CGG+LV +VLTAAHC + V LG HN+
Sbjct: 25 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
Query: 81 EQERTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKWTTAVRPLRL 129
E E T Q +PV PHP YN ++ S+D+MLL+L AK T V+ L L
Sbjct: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
Query: 130 PSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTVQKDCQCERLFHGNYSRATE-- 185
P+ + + G C +GWG + +LQ V L + + C R + + TE
Sbjct: 142 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYS---EKVTEFM 196
Query: 186 ICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK---GTPPGVYIKVSHFLPWIKRT 242
+C G + GDSGGPLVC V QGI S+G + P VY KV H+ WIK T
Sbjct: 197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 256
Query: 243 M 243
+
Sbjct: 257 I 257
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 131 bits (329), Expect = 6e-31
Identities = 78/252 (30%), Positives = 128/252 (50%), Gaps = 16/252 (6%)
Query: 3 PFLLLLAFLLTPGAGT------EEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRK 56
P+ L +L+ AG+ +II G + PHS+P+ A + E C G+LV
Sbjct: 7 PWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELF---CSGVLVHP 63
Query: 57 DFVLTAAHCQGSSINVTLGAHNIK-EQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLE 115
+VL+AAHC +S + LG H+++ +QE Q + + HP YN +ND+ML++L+
Sbjct: 64 QWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD 123
Query: 116 RKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERL 175
+ +R + + S G C V+GWG ++ + T LQ V ++V + C +L
Sbjct: 124 ESVSESDTIRSISIASQCPTA--GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKL 181
Query: 176 FHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKV 232
+ Y + C G + GDSGGPL+C QG++S+G + PGVY +
Sbjct: 182 YDPLY-HPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL 240
Query: 233 SHFLPWIKRTMK 244
F WI++T++
Sbjct: 241 CKFTEWIEKTVQ 252
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 130 bits (328), Expect = 8e-31
Identities = 84/247 (34%), Positives = 133/247 (53%), Gaps = 15/247 (6%)
Query: 7 LLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQ 66
LL+ L G IG E +P+S+P+ A + L +R CG L+ ++LTAAHC+
Sbjct: 9 LLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHL---TRLFCGATLISDRWLLTAAHCR 65
Query: 67 GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYN----PKNFSNDIMLLQLERKAKWTT 122
+ V LG H++ + E +Q V PHP +N + ++DIML++L R+A+ +
Sbjct: 66 KPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSP 125
Query: 123 AVRPLRLPSSKAQVKPGQLCSVAGWGYVS--MSTLATTLQEVLLTVQKDCQCERLFHGNY 180
AV+PL L S+ V PG C ++GWG VS + TLQ +++ ++ C + G+
Sbjct: 126 AVQPLNL--SQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHI 183
Query: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLP 237
S + +C G + + +GDSGGPLVC G++S G + + P VY V H+L
Sbjct: 184 SDSM-LCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLD 242
Query: 238 WIKRTMK 244
WI+ M+
Sbjct: 243 WIQEIME 249
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 129 bits (323), Expect = 3e-30
Identities = 84/250 (33%), Positives = 126/250 (50%), Gaps = 14/250 (5%)
Query: 1 MQPFLLLL---AFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKD 57
M PFL+L A + P ++I+GG+ + +S PY Q CGG L+ +
Sbjct: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPY----QVSLNSGSHFCGGSLISEQ 56
Query: 58 FVLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERK 117
+V++AAHC + I V LG HNIK E +QFI + I HP YN NDIML++L
Sbjct: 57 WVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSP 116
Query: 118 AKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSM--STLATTLQEVLLTVQKDCQCERL 175
A V + LP+ A G C ++GWG + L+ + V +C+
Sbjct: 117 AVINARVSTISLPT--APPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS 174
Query: 176 FHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKG--TPPGVYIKVS 233
+ G + + CVG + + + DSGGP+VC QG++S+G+ PGVY KV
Sbjct: 175 YPGKITNSM-FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVY 233
Query: 234 HFLPWIKRTM 243
+++ WIK T+
Sbjct: 234 NYVDWIKDTI 243
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 126 bits (316), Expect = 2e-29
Identities = 85/252 (33%), Positives = 128/252 (50%), Gaps = 17/252 (6%)
Query: 3 PFLLLLAFLLTPGAGTE----EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDF 58
P +LL L AG E +II G S P+ L ++ CGG+LV + +
Sbjct: 8 PLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVA---LLSGNQLHCGGVLVNERW 64
Query: 59 VLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118
VLTAAHC+ + V LG+ + + R Q I + HP Y+ + ND+ML++L +A
Sbjct: 65 VLTAAHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQA 122
Query: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERLF 176
+ ++ V+ +RLPS PG C+V+GWG + T + L V + + C +++
Sbjct: 123 RLSSMVKKVRLPSRCEP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 177 HGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN-KKGTP--PGVYIKVS 233
+ +C G P + GDSGGPLVC+ QG++S+G G P PGVY +V
Sbjct: 181 KDLLENSM-LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVC 239
Query: 234 HFLPWIKRTMKR 245
F WI TMK+
Sbjct: 240 KFTKWINDTMKK 251
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 126 bits (316), Expect = 2e-29
Identities = 85/252 (33%), Positives = 128/252 (50%), Gaps = 17/252 (6%)
Query: 3 PFLLLLAFLLTPGAGTE----EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDF 58
P +LL L AG E +II G S P+ L ++ CGG+LV + +
Sbjct: 8 PLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVA---LLSGNQLHCGGVLVNERW 64
Query: 59 VLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118
VLTAAHC+ + V LG+ + + R Q I + HP Y+ + ND+ML++L +A
Sbjct: 65 VLTAAHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQA 122
Query: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERLF 176
+ ++ V+ +RLPS PG C+V+GWG + T + L V + + C +++
Sbjct: 123 RLSSMVKKVRLPSRCEP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 177 HGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGN-KKGTP--PGVYIKVS 233
+ +C G P + GDSGGPLVC+ QG++S+G G P PGVY +V
Sbjct: 181 KDLLENSM-LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVC 239
Query: 234 HFLPWIKRTMKR 245
F WI TMK+
Sbjct: 240 KFTKWINDTMKK 251
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 125 bits (315), Expect = 3e-29
Identities = 83/239 (34%), Positives = 119/239 (49%), Gaps = 22/239 (9%)
Query: 21 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 80
I+GG E + HS+P+ V + R CGG+LV +VLTAAHC + + LG H++
Sbjct: 25 IVGGWECEKHSQPWQVLVA---SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
Query: 81 EQERTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKWTTAVRPLRL 129
E T Q V PHP Y+ + S+D+MLL+L A+ T AV+ + L
Sbjct: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141
Query: 130 PSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHGNYSRATEIC 187
P+ + + G C +GWG + T LQ V L V + C ++ H +C
Sbjct: 142 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV-HPQKVTKFMLC 198
Query: 188 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK---GTPPGVYIKVSHFLPWIKRTM 243
G ++ GDSGGPLVC V QGI S+G++ P +Y KV H+ WIK T+
Sbjct: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 124 bits (310), Expect = 1e-28
Identities = 84/247 (34%), Positives = 124/247 (50%), Gaps = 15/247 (6%)
Query: 5 LLLLAFLLT----PGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVL 60
LL+L F+ P ++I+GG+ + +S PY Q CGG L+ + +V+
Sbjct: 4 LLILTFVAAAVAAPFDDDDKIVGGYICEENSVPY----QVSLNSGYHFCGGSLISEQWVV 59
Query: 61 TAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
+A HC S I V LG HNI+ E +QFI + I HP YN + NDI+L++L A
Sbjct: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
Query: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYV--SMSTLATTLQEVLLTVQKDCQCERLFHG 178
+ V + LP+ A G ++GWG S + LQ + V +CE + G
Sbjct: 120 NSRVSAISLPT--APPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
Query: 179 NYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILS--YGNKKGTPPGVYIKVSHFL 236
+ CVG + + +GDSGGP+V QGI+S YG + PGVY KV +++
Sbjct: 178 KITN-NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYV 236
Query: 237 PWIKRTM 243
WIK T+
Sbjct: 237 DWIKDTI 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,379,752
Number of Sequences: 37866
Number of extensions: 455179
Number of successful extensions: 1460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 842
Number of HSP's gapped (non-prelim): 188
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.