BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] (1374 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 2891 0.0 gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 2791 0.0 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 89 2e-17 gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 84 9e-16 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 84 9e-16 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 79 2e-14 gi|160707881 formin 2 [Homo sapiens] 79 4e-14 gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 78 7e-14 gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 78 7e-14 gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 78 7e-14 gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 78 7e-14 gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 78 7e-14 gi|11386183 WAS protein family, member 2 [Homo sapiens] 77 9e-14 gi|47132519 Ras association and pleckstrin homology domains 1 is... 77 1e-13 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 76 3e-13 gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 76 3e-13 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 4e-13 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 75 6e-13 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 1e-12 gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 74 1e-12 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 74 1e-12 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 73 2e-12 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 72 3e-12 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 72 3e-12 gi|153792074 proline rich 12 [Homo sapiens] 72 4e-12 gi|157168329 formin 1 [Homo sapiens] 72 5e-12 gi|210032580 SET domain containing 1B [Homo sapiens] 72 5e-12 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 71 6e-12 >gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] Length = 1374 Score = 2891 bits (7494), Expect = 0.0 Identities = 1374/1374 (100%), Positives = 1374/1374 (100%) Query: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS Sbjct: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 Query: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM Sbjct: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 Query: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP Sbjct: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 Query: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR Sbjct: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 Query: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS Sbjct: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 Query: 301 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK 360 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK Sbjct: 301 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK 360 Query: 361 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 420 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN Sbjct: 361 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 420 Query: 421 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 480 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS Sbjct: 421 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 480 Query: 481 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 540 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA Sbjct: 481 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 540 Query: 541 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 600 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI Sbjct: 541 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 600 Query: 601 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 660 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY Sbjct: 601 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 660 Query: 661 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 720 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA Sbjct: 661 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 720 Query: 721 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 780 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA Sbjct: 721 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 780 Query: 781 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 840 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV Sbjct: 781 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 840 Query: 841 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 900 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP Sbjct: 841 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 900 Query: 901 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 960 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS Sbjct: 901 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 960 Query: 961 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 1020 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR Sbjct: 961 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 1020 Query: 1021 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1080 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN Sbjct: 1021 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1080 Query: 1081 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1140 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL Sbjct: 1081 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1140 Query: 1141 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1200 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA Sbjct: 1141 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1200 Query: 1201 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1260 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND Sbjct: 1201 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1260 Query: 1261 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1320 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA Sbjct: 1261 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1320 Query: 1321 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1374 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK Sbjct: 1321 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1374 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 2791 bits (7236), Expect = 0.0 Identities = 1336/1374 (97%), Positives = 1336/1374 (97%), Gaps = 37/1374 (2%) Query: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS Sbjct: 1 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS 60 Query: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM Sbjct: 61 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 Query: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP Sbjct: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 Query: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR Sbjct: 181 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR 240 Query: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS Sbjct: 241 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS 300 Query: 301 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK 360 PSLERSYKKEYKRSG RSPSREK Sbjct: 301 PSLERSYKKEYKRSGS-------------------------------------RSPSREK 323 Query: 361 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 420 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN Sbjct: 324 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN 383 Query: 421 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 480 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS Sbjct: 384 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS 443 Query: 481 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 540 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA Sbjct: 444 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA 503 Query: 541 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 600 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI Sbjct: 504 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI 563 Query: 601 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 660 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY Sbjct: 564 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY 623 Query: 661 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 720 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA Sbjct: 624 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA 683 Query: 721 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 780 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA Sbjct: 684 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA 743 Query: 781 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 840 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV Sbjct: 744 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV 803 Query: 841 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 900 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP Sbjct: 804 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP 863 Query: 901 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 960 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS Sbjct: 864 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS 923 Query: 961 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 1020 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR Sbjct: 924 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR 983 Query: 1021 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1080 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN Sbjct: 984 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN 1043 Query: 1081 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1140 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL Sbjct: 1044 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL 1103 Query: 1141 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1200 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA Sbjct: 1104 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA 1163 Query: 1201 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1260 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND Sbjct: 1164 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND 1223 Query: 1261 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1320 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA Sbjct: 1224 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA 1283 Query: 1321 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1374 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK Sbjct: 1284 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK 1337 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 89.4 bits (220), Expect = 2e-17 Identities = 104/369 (28%), Positives = 128/369 (34%), Gaps = 92/369 (24%) Query: 19 PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDF 78 P+G G G P A P R P P P P P P PP P Sbjct: 198 PQGGRGRGRFPGAV---PGGDRFPGPAGPG------GPPPPFPAGQTPPRPPLGPPGPPG 248 Query: 79 VPFPPP----MPPSAQGP-----LPPCPI--------RPPFPNHQMRHPFPVPPCFPPMP 121 P PPP +PP GP PP P+ +PP P PVP PP Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308 Query: 122 PPMPCPNNPP----VPGAPPGQGTFPF-MMPPPSMPHPPP----------PPVMPQQVN- 165 PP P PP P PPG P + PPP +P PPP P P N Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 Query: 166 ---------------YQYPPGYSHHNFPPP--------------SFNSFQNNPSSFLPSA 196 Y PP Y ++ PP F N + SA Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSA 428 Query: 197 -----NNSSSPHF--------RHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 +++S+ + + K ++ R + D H S G Sbjct: 429 ISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYG-- 486 Query: 244 HRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSL 303 S RRER R D R SR +S + R+ RH Y R R RERERHR RD R Sbjct: 487 --SGSRRERSRERDHSR--SREKSRRHKSRSRDRHDDYYRERSRERERHRDRD--RDRDR 540 Query: 304 ERSYKKEYK 312 ER ++EY+ Sbjct: 541 ERDREREYR 549 Score = 88.2 bits (217), Expect = 5e-17 Identities = 94/339 (27%), Positives = 122/339 (35%), Gaps = 66/339 (19%) Query: 19 PRGRGGH------GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFL 72 P G GG G P P P PP Q P + P P P Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPP-----PMP 125 P +P P P+PP GP PP P PP P + P P P FPP PP P+ Sbjct: 280 PGQPFGQPPLGPLPP---GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336 Query: 126 CPNNPPVPGAPPGQG-----TFPFMMPPPSMPHPP------PPPVMPQQVNYQYPPGYSH 174 P +PG PPG P PPP+ P PPP P Y PP Y Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDP----YGRPPPYDR 392 Query: 175 HNFPPPS--------------FNSFQNNPSSFLPSA-----NNSSSPHFRH--------L 207 ++ PP F N + SA +++S+ + + Sbjct: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAI 452 Query: 208 PPYPLPKAPSERRSPERLKHYDDHRH--RDHSHGRGERHRSLDRRERGRSPDR-RRQDSR 264 K ++ R + D H S+G G R R+ RS ++ RR SR Sbjct: 453 SLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSR 512 Query: 265 YRSDYD-----RGRTPSRHRSYERSRERERERHRHRDNR 298 R +D R R RHR +R R+RER+R R +R Sbjct: 513 SRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR 551 >gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] Length = 588 Score = 84.0 bits (206), Expect = 9e-16 Identities = 74/222 (33%), Positives = 93/222 (41%), Gaps = 34/222 (15%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173 PP FPP PP P P +P PP T P ++PPP +P PPP P PPG Sbjct: 342 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGIPITVPPPGFPP------PPG-- 392 Query: 174 HHNFPPPS-FNSFQNNPSSFLPSANNSSSPH----FRHLPPYPLPKAPS----------- 217 PPPS + ++ SS S + + P+ F HLP P PS Sbjct: 393 ---APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG-SAPSWPSLVDTSKQWDYY 448 Query: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPS 276 RR +R + D R RD R ER R+ RER R D S + SD +R R Sbjct: 449 ARREKDRDRERDRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREY 504 Query: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSY 318 R YER R + RHR+ R E +K S R + Sbjct: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH 546 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 84.0 bits (206), Expect = 9e-16 Identities = 74/231 (32%), Positives = 97/231 (41%), Gaps = 38/231 (16%) Query: 21 GRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVP 80 G+ G G APS R N + P PP P +T+ ++ A PPRP+ Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPAS-----PRLGNTSEAHGAART-APPRPNVPA 173 Query: 81 FPPPMPPSAQGPLPP-----CPIR-----PPFPNHQMRHPFPVPP--CFPPMPPPMPCPN 128 PPP PP PLPP PI+ PP P + P PP C PP PPP P P Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233 Query: 129 NPPVPGAP--PGQGTFPFMMPPPSMPHPPPPPVMP-------------QQVNYQYPPGYS 173 PP+P A + P + P P PPP P++P + Q PP Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP 293 Query: 174 HHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPER 224 P S + + P+ LP N+SS PP P PK+PS + P++ Sbjct: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETP----PPLP-PKSPSFQAPPQK 339 Score = 55.1 bits (131), Expect = 5e-07 Identities = 58/199 (29%), Positives = 68/199 (34%), Gaps = 70/199 (35%) Query: 25 HGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPA------------PNFL 72 HGA +AP RP N+ P PP PP PS++ +P P Sbjct: 159 HGAARTAPP-RP-NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVA 216 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPC------------------PIRPPFP----------- 103 PP P P PPP PP PLPP PI PP P Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276 Query: 104 ------NHQMRHPFPVPPCFPPMPPPMPCPNN-----PPVPGA-------PPGQGTFPFM 145 + P P PP PP+PP C PP+PG PP P Sbjct: 277 AEPASPAQDAQEP-PAPP--PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333 Query: 146 MPPP------SMPHPPPPP 158 PP ++P PP PP Sbjct: 334 QAPPQKAGAQALPAPPAPP 352 Score = 48.9 bits (115), Expect = 3e-05 Identities = 42/134 (31%), Positives = 49/134 (36%), Gaps = 35/134 (26%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSP-----APNFLPPRPDFVPFPPPM--------PPS-- 88 P PP PP P++ S+ AP LPP P +P PP P S Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283 Query: 89 --AQGPLPPCPIRPPFPNHQMRHPFPVPPCF---------PPMPPPMPCPNNPP------ 131 AQ P P P PP+ + R P PP PP+PP P PP Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343 Query: 132 ---VPGAPPGQGTF 142 P APPG F Sbjct: 344 ALPAPPAPPGSQPF 357 Score = 36.2 bits (82), Expect = 0.22 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Query: 110 PFPVPPCFPPMPPPMPCPNNPPVPGAPP 137 P P PP PP PPP+ P PP P APP Sbjct: 4 PPPPPPPLPPPPPPLGAP-PPPPPSAPP 30 Score = 35.4 bits (80), Expect = 0.38 Identities = 21/41 (51%), Positives = 22/41 (53%), Gaps = 13/41 (31%) Query: 112 PVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMP 152 PVPP P PPP+P P PP GAPP PPPS P Sbjct: 2 PVPP---PPPPPLPPP--PPPLGAPP--------PPPPSAP 29 Score = 32.7 bits (73), Expect = 2.5 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 23/54 (42%) Query: 79 VPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 +P PPP PP PLPP P PP P PPP P+ PPV Sbjct: 1 MPVPPPPPP----PLPP----------------PPPPLGAPPPPP---PSAPPV 31 Score = 32.3 bits (72), Expect = 3.2 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 7/54 (12%) Query: 120 MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173 MP P P P PP+P PP P PPP P PP + P G S Sbjct: 1 MPVPPPPP--PPLPPPPP-----PLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47 Score = 32.0 bits (71), Expect = 4.2 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 14/43 (32%) Query: 119 PMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161 P+PPP P PP+P PP P P PPPP P Sbjct: 2 PVPPPPP----PPLPPPPP----------PLGAPPPPPPSAPP 30 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 79.3 bits (194), Expect = 2e-14 Identities = 58/160 (36%), Positives = 66/160 (41%), Gaps = 18/160 (11%) Query: 26 GARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPP-- 83 GA +AP+ P L PQ P PP P P +PPRP P PP Sbjct: 221 GAYYAAPALDPALCVHLVPQLP------RPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMA 274 Query: 84 PMPP-SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMP--PPM-PCPNNPPVPGAPPGQ 139 P+PP S P+PP P P P P P P P+P PPM P P PP+ PPG Sbjct: 275 PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGP 334 Query: 140 GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPP 179 PP P PP PP+ P PPG PP Sbjct: 335 PMARVPPGPPMAPLPPGPPMAP------LPPGPPMAPLPP 368 Score = 66.2 bits (160), Expect = 2e-10 Identities = 49/138 (35%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 32 PSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNS----PAPNF--LPPRPDFVPFP--P 83 P P+ + P +PP+ PP AP S P P +PP P P P P Sbjct: 250 PPMPPRPPMVPMPPRPPIAPM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP 307 Query: 84 PMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFP 143 PM P GP P P+ PP P P P PP PP P P PP+ PPG Sbjct: 308 PMAPVPTGP-PMAPV-PPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG----- 360 Query: 144 FMMPPPSMPHPPPPPVMP 161 PP P PP PP+ P Sbjct: 361 ----PPMAPLPPGPPMAP 374 Score = 42.7 bits (99), Expect = 0.002 Identities = 26/79 (32%), Positives = 28/79 (35%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 PP P P +PP P PP P + P PP PP P P P Sbjct: 304 PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPM 363 Query: 115 PCFPPMPPPMPCPNNPPVP 133 PP PP P P VP Sbjct: 364 APLPPGPPMAPLPPRSHVP 382 Score = 32.3 bits (72), Expect = 3.2 Identities = 21/52 (40%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPP 95 P PP+ PP P P LPP P P PP PP A PLPP Sbjct: 331 PPGPPMARV--PPGPPMAPLPPGPPMAPLPPGPPMAPLPPG-PPMA--PLPP 377 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 78.6 bits (192), Expect = 4e-14 Identities = 68/198 (34%), Positives = 82/198 (41%), Gaps = 26/198 (13%) Query: 44 PQQPPVQ-YQYEPPSAPSTTFSNSPAPNFLP-----PRPDF----VPFPPPMPPSAQGPL 93 PQ PP+Q + PP P + P P LP P P +P PPP+P +A P Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956 Query: 94 PPCP-----IRPPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGA---PPGQGTF 142 PP P + PP P + P P+P P PPP+P P PP+PGA PP Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016 Query: 143 PFMMPPPSMPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200 + PPP +P PPPP +P PP PPP P LP A Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076 Query: 201 SPHFRHL---PPYPLPKA 215 P PP PLP A Sbjct: 1077 PPPLPGAGIPPPPPLPGA 1094 Score = 72.4 bits (176), Expect = 3e-12 Identities = 62/190 (32%), Positives = 74/190 (38%), Gaps = 23/190 (12%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95 P PP+ PP P P P +PP P +P PPP+P + P PP Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035 Query: 96 CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPS 150 P PP P + P P+P P PPP+P PP P PG G + PPP Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAG----IPPPPP 1090 Query: 151 MPHP--PPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHL- 207 +P PPPP +P PP PPP P LP A P + Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150 Query: 208 --PPYPLPKA 215 PP PLP A Sbjct: 1151 IPPPPPLPGA 1160 Score = 66.6 bits (161), Expect = 2e-10 Identities = 55/170 (32%), Positives = 67/170 (39%), Gaps = 33/170 (19%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF----LPPRPDF----VPFPPPMPPSAQGPLPP 95 P PP+ PP P P P +PP P +P PPP+P P PP Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156 Query: 96 CPIR-----PPFPNHQMRHPFPVPPCFPPMPPPMPC---PNNPPVPGAP-------PGQG 140 P PP P + P P+P P PPP+P P PP+PGA PG G Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216 Query: 141 TFPF---MMPPPSMPHPPP-------PPVMPQQVNYQYPPGYSHHNFPPP 180 P +PPP PPP PP++PQ + P PPP Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266 Score = 59.7 bits (143), Expect = 2e-08 Identities = 63/199 (31%), Positives = 73/199 (36%), Gaps = 38/199 (19%) Query: 46 QPP----VQYQYEPPSAPSTTFSNS---PAPNFLP--------PRPDFVPFPPPMPPSAQ 90 QPP ++Q + S+ F NS P+P LP P VP PPP P Sbjct: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887 Query: 91 GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF------ 144 P P P P P PP PPP+P PP P P G G P Sbjct: 888 VPTLPSTAIPQPP------PLQGTEMLPPPPPPLPGAGIPPPPPLP-GAGILPLPPLPGA 940 Query: 145 -MMPPPSMPH---PPPPPVMPQQVNYQYP-PGYSHHNFPPPSFNSFQNNPSSFLPSANNS 199 + PPP +P PPPPP+ + P PG PPP P LP A Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIP 998 Query: 200 SSPHFRHL---PPYPLPKA 215 P PP PLP A Sbjct: 999 PPPPLPGAGIPPPPPLPGA 1017 Score = 45.4 bits (106), Expect = 4e-04 Identities = 46/151 (30%), Positives = 56/151 (37%), Gaps = 24/151 (15%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNF-- 71 PG G P GA P P R+ P PP+ PP P P P Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLP---RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181 Query: 72 --LPPRPDF----VPFPPPMPPSAQGPLPPCPIR--PPFPNHQMRHPFPVPPCFPPMPPP 123 +PP P +P PPP+P + P PP P PP P P+PP +PPP Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP------PLPPPGTGIPPP 1235 Query: 124 MPCPNNPPVPGAPPGQGTFPF-----MMPPP 149 P + P G T P +PPP Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266 Score = 32.3 bits (72), Expect = 3.2 Identities = 29/117 (24%), Positives = 40/117 (34%), Gaps = 24/117 (20%) Query: 120 MPPPMPCPNNPPVP-GAPPGQGT------------------FPFMMPPPSMPHPPPPPVM 160 +PP P PP P GA G T P S+ PPPPP + Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816 Query: 161 PQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPS 217 P H+ S +++ SS ++ N SP PP P ++ S Sbjct: 817 LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP-----PPLPCTESSS 868 >gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] Length = 520 Score = 77.8 bits (190), Expect = 7e-14 Identities = 68/211 (32%), Positives = 86/211 (40%), Gaps = 21/211 (9%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171 PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G Sbjct: 283 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 341 Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228 Y S FP + N LP S+P + L RR +R + Sbjct: 342 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 391 Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287 D R RD R ER R+ RER R D S + SD +R R R YER R Sbjct: 392 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 447 Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGRSY 318 + RHR+ R E +K S R + Sbjct: 448 REKEERHRERRHREKEETRHKSSRSNSRRRH 478 >gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] Length = 594 Score = 77.8 bits (190), Expect = 7e-14 Identities = 68/211 (32%), Positives = 86/211 (40%), Gaps = 21/211 (9%) Query: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171 PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G Sbjct: 357 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 415 Query: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228 Y S FP + N LP S+P + L RR +R + Sbjct: 416 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 465 Query: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287 D R RD R ER R+ RER R D S + SD +R R R YER R Sbjct: 466 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521 Query: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGRSY 318 + RHR+ R E +K S R + Sbjct: 522 REKEERHRERRHREKEETRHKSSRSNSRRRH 552 >gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] Length = 1125 Score = 77.8 bits (190), Expect = 7e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 784 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 838 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 839 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 897 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 898 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 954 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 955 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1004 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1005 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1054 Score = 62.4 bits (150), Expect = 3e-09 Identities = 87/305 (28%), Positives = 106/305 (34%), Gaps = 30/305 (9%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHR 279 E L H + +RH S +R+ R RS R + R RS R SRHR Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRR--SRHR 460 Query: 280 SYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL-SVVPEPAG-CTPEL-PGE 336 RSR R R+R RH + RS S ER +E +R R GL V PE A C+ L G+ Sbjct: 461 ---RSRSRSRDRRRH--SPRSRSQERR-DREKERERRQKGLPQVKPETASVCSTTLWVGQ 514 Query: 337 IIKNT 341 + K T Sbjct: 515 LDKRT 519 Score = 61.2 bits (147), Expect = 6e-09 Identities = 92/356 (25%), Positives = 123/356 (34%), Gaps = 86/356 (24%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPP-------PM--PPSAQGPL 93 H PPV +PP+ T P P F P P P PP PM PP P Sbjct: 685 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742 Query: 94 PPCPIRPPF---PNHQMRHPFP----------------------VPPCFP---PMPPPMP 125 PP PI PP P H P VPP P P PP Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802 Query: 126 CPNNPPVPGAPPGQ------------GTFPFMMP---PPSMPHP--------PPPPVMPQ 162 + G PG G P ++P PP MP P PP P+ P Sbjct: 803 PVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPH 862 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 ++ PPG PPP P P P P P P P +R Sbjct: 863 MMHRGPPPGPGGFAMPPPHGMKGPFPPHG--PFVRPGGMPGLG--GPGPGPGGPEDRDGR 918 Query: 223 ERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSD----YDRGRTPSR- 277 ++ + + + + ++ + + P ++Q ++R+D ++ GR R Sbjct: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERF 978 Query: 278 -HRSY----ERSRERERERHRHRDN---------RRSPSLERSYKKEYKRSGRSYG 319 RS+ E RER R+ RDN RRSP +R E +R+ RS G Sbjct: 979 GRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLE-ERNRRSSG 1033 Score = 52.4 bits (124), Expect = 3e-06 Identities = 48/150 (32%), Positives = 57/150 (38%), Gaps = 44/150 (29%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPPSFNSFQNNPS 190 P T P +PPP P PPPPP + N + PPG+ PPP P Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI-----TPPV 751 Query: 191 SFLPSANNSSSPHFRHLPPYPLPKAPSERR 220 S P H PP +P S R Sbjct: 752 SIPPP----------HTPPISIPNLVSGAR 771 Score = 52.0 bits (123), Expect = 4e-06 Identities = 46/127 (36%), Positives = 56/127 (44%), Gaps = 20/127 (15%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHP- 154 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP-PG 742 Query: 155 PPPPVMP 161 PPPP+ P Sbjct: 743 PPPPITP 749 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 957 Query: 74 PR 75 P+ Sbjct: 958 PQ 959 >gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo sapiens] Length = 1132 Score = 77.8 bits (190), Expect = 7e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 791 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 845 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 846 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 904 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 905 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 961 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 962 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1011 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1012 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1061 Score = 62.4 bits (150), Expect = 3e-09 Identities = 87/305 (28%), Positives = 106/305 (34%), Gaps = 30/305 (9%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 223 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 282 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 283 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 329 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 330 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 387 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHR 279 E L H + +RH S +R+ R RS R + R RS R SRHR Sbjct: 388 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRR--SRHR 445 Query: 280 SYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL-SVVPEPAG-CTPEL-PGE 336 RSR R R+R RH + RS S ER +E +R R GL V PE A C+ L G+ Sbjct: 446 ---RSRSRSRDRRRH--SPRSRSQERR-DREKERERRQKGLPQVKPETASVCSTTLWVGQ 499 Query: 337 IIKNT 341 + K T Sbjct: 500 LDKRT 504 Score = 57.0 bits (136), Expect = 1e-07 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 619 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 668 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 669 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 728 Query: 156 PPPVMP 161 PPP+ P Sbjct: 729 PPPITP 734 Score = 51.6 bits (122), Expect = 5e-06 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 642 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 681 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180 P T P +PPP P PPPPP + N + PPG+ PPP Sbjct: 682 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 731 Score = 48.9 bits (115), Expect = 3e-05 Identities = 87/381 (22%), Positives = 127/381 (33%), Gaps = 114/381 (29%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPI---- 98 H PPV +PP+ T P P F P VP PPP PP + P + Sbjct: 670 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPG----VPPPPPPPPFLRPGFNPMHLPPGF 723 Query: 99 RPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNP----------------PVPGAPPG---- 138 PP P + P +P PP PP+ PN+ P+P G Sbjct: 724 LPPGPPPPITPPVSIP---PPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGN 780 Query: 139 ---------QGTFPFMMPPPSMPHPP--------------PPPVM-------------PQ 162 G+ P ++P PP P PV+ P Sbjct: 781 AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPG 840 Query: 163 QVNYQYPPG-------------------YSHHNFPPPSFNSFQNNPSSFLPSANNSSSPH 203 + Q PPG + H PPP F P + P Sbjct: 841 LIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF 900 Query: 204 FR--HLP----PYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPD 257 R +P P P P P +R ++ + + + + ++ + + P Sbjct: 901 VRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 960 Query: 258 RRRQDSRYRSD----YDRGRTPSR--HRSY----ERSRERERERHRHRDN---------R 298 ++Q ++R+D ++ GR R RS+ E RER R+ RDN R Sbjct: 961 TQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGR 1020 Query: 299 RSPSLERSYKKEYKRSGRSYG 319 RSP +R E +R+ RS G Sbjct: 1021 RSPDRDRHRDLE-ERNRRSSG 1040 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 914 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 964 Query: 74 PR 75 P+ Sbjct: 965 PQ 966 >gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo sapiens] Length = 1147 Score = 77.8 bits (190), Expect = 7e-14 Identities = 92/297 (30%), Positives = 111/297 (37%), Gaps = 47/297 (15%) Query: 24 GHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFS-NSPAPNFLPPRPDFVPF- 81 G P+AP+ P P PV AP +P+ L RP +P Sbjct: 806 GSAVPPAAPTNLPTP-----PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQ 860 Query: 82 -PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM----PCPNNPPV--PG 134 PP MPP P P RP P+ R P P P F MPPP P P + P PG Sbjct: 861 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF-AMPPPHGMKGPFPPHGPFVRPG 919 Query: 135 APPGQGTFPFMMP-----------PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 PG G P P PP P P P PQQ Q PPP+ Sbjct: 920 GMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPT-- 976 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGER 243 Q P F N + F + RRS D R+ + + R Sbjct: 977 --QQQPQQF----RNDNRQQFNS----GRDQERFGRRSFGNRVENDRERYGNRNDDRDNS 1026 Query: 244 HRSLDRRERG-RSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRR 299 +R DRRE G RSPDR R+R +R R S HR ER R+RE R ++ R Sbjct: 1027 NR--DRREWGRRSPDR----DRHRDLEERNRRSSGHRDRERD-SRDRESRREKEEAR 1076 Score = 62.4 bits (150), Expect = 3e-09 Identities = 87/305 (28%), Positives = 106/305 (34%), Gaps = 30/305 (9%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF 102 P QP Q PP T F F P+ V +A P PP Sbjct: 238 PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA 297 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQ 162 P + P P PPP P PG G M P H P+ Sbjct: 298 PTATV--PAAAAPAAASPPPPQ-------APFGFPGDG----MQQPAYTQHQNMDQFQPR 344 Query: 163 QVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 + Q P HH P P P + P PP P S + Sbjct: 345 MMGIQQDP--MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402 Query: 223 ERLK---HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHR 279 E L H + +RH S +R+ R RS R + R RS R SRHR Sbjct: 403 EPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRR--SRHR 460 Query: 280 SYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL-SVVPEPAG-CTPEL-PGE 336 RSR R R+R RH + RS S ER +E +R R GL V PE A C+ L G+ Sbjct: 461 ---RSRSRSRDRRRH--SPRSRSQERR-DREKERERRQKGLPQVKPETASVCSTTLWVGQ 514 Query: 337 IIKNT 341 + K T Sbjct: 515 LDKRT 519 Score = 57.0 bits (136), Expect = 1e-07 Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P++P + + S T SP P LP VP PP +P A +PP P P Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLP-----VPVPP-IPVPAPITVPP----PQVP 683 Query: 104 NHQMRHPFP---VPPCFPP---MPPPMPCPNNPPVPGAPP--GQGTFPFMMPPPSMPHPP 155 HQ P PP F P +PPP P PP P PP G P +PP +P P Sbjct: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 743 Query: 156 PPPVMP 161 PPP+ P Sbjct: 744 PPPITP 749 Score = 51.6 bits (122), Expect = 5e-06 Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 29/110 (26%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPP--MPPPMPCPNNPPVPGA-P 136 P P P+P P+PP P+ P P PP +PP P PPV GA Sbjct: 657 PIPKPLPV----PVPPIPV-------------PAPITVPPPQVPPHQP---GPPVVGALQ 696 Query: 137 PGQGTFPFMMPPPSM-----PHPPPPPVMPQQVNYQY-PPGYSHHNFPPP 180 P T P +PPP P PPPPP + N + PPG+ PPP Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPP 746 Score = 48.9 bits (115), Expect = 3e-05 Identities = 87/381 (22%), Positives = 127/381 (33%), Gaps = 114/381 (29%) Query: 43 HPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPI---- 98 H PPV +PP+ T P P F P VP PPP PP + P + Sbjct: 685 HQPGPPVVGALQPPAF--TPPLGIPPPGFGPG----VPPPPPPPPFLRPGFNPMHLPPGF 738 Query: 99 RPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNP----------------PVPGAPPG---- 138 PP P + P +P PP PP+ PN+ P+P G Sbjct: 739 LPPGPPPPITPPVSIP---PPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGN 795 Query: 139 ---------QGTFPFMMPPPSMPHPP--------------PPPVM-------------PQ 162 G+ P ++P PP P PV+ P Sbjct: 796 AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPG 855 Query: 163 QVNYQYPPG-------------------YSHHNFPPPSFNSFQNNPSSFLPSANNSSSPH 203 + Q PPG + H PPP F P + P Sbjct: 856 LIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF 915 Query: 204 FR--HLP----PYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPD 257 R +P P P P P +R ++ + + + + ++ + + P Sbjct: 916 VRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 975 Query: 258 RRRQDSRYRSD----YDRGRTPSR--HRSY----ERSRERERERHRHRDN---------R 298 ++Q ++R+D ++ GR R RS+ E RER R+ RDN R Sbjct: 976 TQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGR 1035 Query: 299 RSPSLERSYKKEYKRSGRSYG 319 RSP +R E +R+ RS G Sbjct: 1036 RSPDRDRHRDLE-ERNRRSSG 1055 Score = 33.5 bits (75), Expect = 1.4 Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P R G P P +PQ PQQP Q Q +PP S P P Sbjct: 929 PGPGGPEDRDGRQQPPQQPQQQPQPQA---PQQPQQQQQQQPPP------SQQPPPTQQQ 979 Query: 74 PR 75 P+ Sbjct: 980 PQ 981 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 77.4 bits (189), Expect = 9e-14 Identities = 55/160 (34%), Positives = 63/160 (39%), Gaps = 9/160 (5%) Query: 36 PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP--L 93 P+ ++ P PP P P F+ PAP PP P + PPP PP G Sbjct: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPP--PPPPPMIGIPPPPPPVGFGSPGT 346 Query: 94 PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPH 153 PP P P FP H F PP PP PP P PP P + P G P PPP Sbjct: 347 PPPPSPPSFPPHP---DFAAPPP-PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG- 401 Query: 154 PPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFL 193 PPPPP PP S P S + + S L Sbjct: 402 PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLL 441 Score = 62.4 bits (150), Expect = 3e-09 Identities = 57/181 (31%), Positives = 70/181 (38%), Gaps = 32/181 (17%) Query: 29 PSAPSFRPQNLR---LLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM 85 P+ S+ N R L P++ V PP AP P P F PP P PPP Sbjct: 271 PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPP-----PAPPPP 325 Query: 86 PPSAQG-PLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPF 144 PP G P PP P+ P P P PP FPP P P PP Sbjct: 326 PPPMIGIPPPPPPVGFGSPGTP---PPPSPPSFPPHPD-FAAPPPPP------------- 368 Query: 145 MMPPPSMPHP--PPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201 PPP+ +P PPPP+ P PP PPP F P + P ++++ Sbjct: 369 --PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP-AIPPPLSDTTK 425 Query: 202 P 202 P Sbjct: 426 P 426 Score = 60.1 bits (144), Expect = 1e-08 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 34/167 (20%) Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMR----------------HPFPVPPC 116 PP P P P ++ LPP P +P R HP P PP Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306 Query: 117 FPP-------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYP 169 P PPP P P PP+ G PP P P P PP PP P ++ P Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP--PVGFGSPGTPPPPSPPSFPPHPDFAAP 364 Query: 170 PGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 P PPP + P L + P PP P P P Sbjct: 365 PPP-----PPPPAADYPTLPPPPLSQPTGGAPPP----PPPPPPPGP 402 Score = 60.1 bits (144), Expect = 1e-08 Identities = 50/147 (34%), Positives = 59/147 (40%), Gaps = 18/147 (12%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 P G P G A P AP P + + P PPV + P + S P P+F Sbjct: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363 Query: 74 PRPDFVPFPPPMPPSAQGP-LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 P PPP PP+A P LPP P+ P PP PP PPP P P PP Sbjct: 364 PP------PPPPPPAADYPTLPPPPLSQPTGG--------APP--PPPPPPPPGPPPPPF 407 Query: 133 PGAPPGQGTFPFMMPPPSMPHPPPPPV 159 GA GQ P + + P P V Sbjct: 408 TGA-DGQPAIPPPLSDTTKPKSSLPAV 433 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 76.6 bits (187), Expect = 1e-13 Identities = 67/213 (31%), Positives = 79/213 (37%), Gaps = 69/213 (32%) Query: 53 YEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP-----SAQGPLPPCPIRPPFPN--- 104 ++PP+ P S S P L P VP PPP PP SA L P P P P Sbjct: 684 FKPPTPPVMQ-SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA 742 Query: 105 -------HQMRHPFPVPPCFPPMPPPMPCPNNP--------------------------- 130 HQ++H V P PP PPP+P P P Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA 802 Query: 131 ---PVPGAPPG--QGTFPFMMPPPSMPHPP---PPPVMPQQVNYQYPPGYSHHNFPPPSF 182 P P PP Q FP PPS P PP PPP +P+Q ++ PPPS Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK--------PPPS- 853 Query: 183 NSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215 P S +PS + F PP P P A Sbjct: 854 ------PLSPVPSVVKQIASQF---PPPPTPPA 877 Score = 63.2 bits (152), Expect = 2e-09 Identities = 67/210 (31%), Positives = 78/210 (37%), Gaps = 43/210 (20%) Query: 44 PQQPPVQYQYEPPSAPST-TFSNSPAPNFLPPRPDFVPF------PPPMPPSAQG-PLPP 95 P PPV PP+ P +F P P+ L P P V PPP PP+ + PL P Sbjct: 828 PPTPPVPVP--PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885 Query: 96 CP--IRPPFPNHQMRHP-------------FPVPP-----CFPPMPPPMPCPNNPPVPGA 135 P + P P P FP PP FPP PPP P P PP P Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP-PPPSPVPAPPPPP-- 942 Query: 136 PPGQGTFPFMMPPP-------SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNN 188 PP P P S P PP PQ+ + + H P P S + Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH--PEPKRPSVDSL 1000 Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSE 218 S F P A S SP LPP P P + Sbjct: 1001 VSKFTPPA-ESGSPSKETLPPPAAPPKPGK 1029 Score = 60.1 bits (144), Expect = 1e-08 Identities = 67/217 (30%), Positives = 83/217 (38%), Gaps = 41/217 (18%) Query: 29 PSAPSFR--PQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM- 85 PS P F P L++ Q Q PP+ P +P P PP+P V P P Sbjct: 735 PSLPQFSAPPPPLKIHQVQHIT---QVAPPTPPPPPPIPAPLPPQAPPKP-LVTIPAPTS 790 Query: 86 ------------PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPPP-MP-----C 126 PP+ P+PP +P FP + P PP P P+PPP +P C Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP---PSPPTPPVPVPPPTLPKQQSFC 847 Query: 127 PNNPPVPGAPPGQ------GTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGY-SHHNFPP 179 PP P +P FP PP+M P PV P V Q PP + + P Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV-PANVAPQSPPAVKAKPKWQP 906 Query: 180 PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 S PS P SS F PP P+P P Sbjct: 907 SSIPV----PSPDFPPPPPESSLVFPPPPPSPVPAPP 939 Score = 60.1 bits (144), Expect = 1e-08 Identities = 58/189 (30%), Positives = 71/189 (37%), Gaps = 13/189 (6%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDF--VPFPPPMPPSAQG---PLPPCPIRP-PFPNHQMR 108 PP P+ PA +++PP P VP PPP P Q PP P+ P P Q+ Sbjct: 808 PPVPPAKKQPAFPA-SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866 Query: 109 HPFPVPPCFPPMP--PPMPCPNNPPVPGAPPGQGTFPFMMP---PPSMPHPPPPPVMPQQ 163 FP PP P M P P P N P +PP P P P P PPPP Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANV-APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925 Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223 V PP PPP + S P S + P P P+ S +S Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985 Query: 224 RLKHYDDHR 232 +H + R Sbjct: 986 GAEHPEPKR 994 Score = 55.8 bits (133), Expect = 3e-07 Identities = 54/200 (27%), Positives = 64/200 (32%), Gaps = 42/200 (21%) Query: 52 QYEPPSAPSTTFSNSPAPNFLPP---RPDFV----------PFPPPMPPSAQGPLPPCPI 98 Q E S N P + +PP +P V P PPP PP P PP P Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645 Query: 99 RPPFPNHQMRHPFPVPPCF---------------------PPMPPPMPCPNNPPVPGAPP 137 PP P+ P F PP PP M + P PP Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705 Query: 138 GQGTFPFMMPPPSMPHPPPPP--VMPQQVNYQYPPGYSHHNFPPPSFNSFQ-NNPSSFLP 194 ++PPP P PPP P M Q P + PPP Q + + P Sbjct: 706 NG-----VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760 Query: 195 SANNSSSPHFRHLPPYPLPK 214 P LPP PK Sbjct: 761 PTPPPPPPIPAPLPPQAPPK 780 Score = 50.1 bits (118), Expect = 1e-05 Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 36/161 (22%) Query: 92 PLPPCP-IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP--GAPPGQGTFPFMMPP 148 PL P P I P+ Q P P PP PP PPP P P PP+P AP P + Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 Query: 149 PSMPH-------------PPPPPVMPQQ---------VNYQYPPGYSHHNFPPPSFNSFQ 186 ++ PP PPVM Q N PP P P Q Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727 Query: 187 NNPSSFLPSANNSSSP-------HFRHL----PPYPLPKAP 216 P+ PS S+P +H+ PP P P P Sbjct: 728 LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768 Score = 44.3 bits (103), Expect = 8e-04 Identities = 52/207 (25%), Positives = 62/207 (29%), Gaps = 78/207 (37%) Query: 29 PSAPSFRPQNLRLLH----PQQPPV---QYQYEPPSAPSTTFSNSPAPN-----FLPPRP 76 P+ P+ Q L+ + PQ PP + +++P S P + P P F PP P Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932 Query: 77 DFVPFPPPMPPSAQGPLP---------------PCPIRPPFPNHQMR----------HPF 111 VP PPP PP P P P +PP P Q HP Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPE 991 Query: 112 PVPPCF--------PPMPPPMPCPNNPPVPGAPPGQGTF--------------------- 142 P P PP P P P APP G Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 Query: 143 -----------PFMMPPPSMPHPPPPP 158 F PP PPPPP Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPP 1078 Score = 41.2 bits (95), Expect = 0.007 Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 23/138 (16%) Query: 98 IRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPP 157 + P P ++ P+ PP+PPP P P PP P PP P PS P Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP-------PLPSQSAPSAG 658 Query: 158 PVMPQQVNY------QYPPGYSHHNFPPPS---FNSFQNNPSSFLPSANNSSSPHFRHLP 208 P V Y Q +S F PP+ S P +P N P P Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP--NGVVP-----P 711 Query: 209 PYPLPKAPSERRSPERLK 226 P P P P+ + +LK Sbjct: 712 PPPPPPPPTPGSAMAQLK 729 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 75.9 bits (185), Expect = 3e-13 Identities = 126/498 (25%), Positives = 178/498 (35%), Gaps = 116/498 (23%) Query: 56 PSAPST-TFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 PS P+T F P P PP P +P PP +PP P P P +PP + + P Sbjct: 548 PSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFP-PGQPPPAGYSV-----PP 601 Query: 115 PCFPPMPPPMPCP-----------NNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQ 163 P FPP P + P N P APP F + P Sbjct: 602 PGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPP-LSREEFYREQRRLKEESKSPYSGS- 659 Query: 164 VNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPE 223 YS ++ S S+ S + S S + PPYP RR Sbjct: 660 -------SYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYP-------RRGRG 705 Query: 224 RLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYD-RGRTPSRHRSYE 282 + ++Y R R SHG HRS R RSP RR SR RS RG++P++ + Sbjct: 706 KSRNY---RSRSRSHG---YHRS-----RSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQ 754 Query: 283 RSRERER-ERHRH-----------------RD---NRRSPSLERSYKKEYKRSGRSYGLS 321 ERE R+R RD R ER Y++ Y++ + Y Sbjct: 755 GETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAG 814 Query: 322 VVPEPAGCTPELPGEIIKNTDSWAP----PLEIVNHRSPSREKKRARWEEEKDRWSDNQS 377 P P+ N ++++P PL I N SP +R + + S N Sbjct: 815 AQPRPSA-----------NRENFSPERFLPLNIRN--SPFTRGRREDYVGGQSHRSRNIG 861 Query: 378 SG-----------KDKNYTSIKEKEPEETMPD------------KNEEEEEELLKPVWIR 414 S K+ T KEKE E D + EE E L P + Sbjct: 862 SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLE 921 Query: 415 CTHSENYYSSDPMDQVGDSTVVGTSR-----LRDL---YDKFEEELGSRQEKAKAARPPW 466 T ++ + + DS V SR +RD + + S ++K + +P Sbjct: 922 -TSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKA 980 Query: 467 EPPKTKLDEDLESSSESE 484 + KTK D + S+ E Sbjct: 981 KGDKTKRKNDGSAVSKKE 998 Score = 41.6 bits (96), Expect = 0.005 Identities = 66/317 (20%), Positives = 126/317 (39%), Gaps = 39/317 (12%) Query: 195 SANNSSSPHFRHLPPYPLPKAPSERRSPER--LKHYDDHRHRDHSHGRGERHRSLDRRER 252 S+N +P+ Y + S +R E+ L D R+ G++++ + R+ Sbjct: 1428 SSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDL 1487 Query: 253 GR-----------SPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSP 301 + SP R R+ +++ YD R +S +++ ++RE+H Sbjct: 1488 PKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKH--------- 1538 Query: 302 SLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSP--SRE 359 LE KE + Y L+ PE ++ G+I K+T P L + S +RE Sbjct: 1539 VLEARNNKESSGNKLLYILN-PPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRE 1597 Query: 360 KKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEP----EETMPDKNEEEEEELLKP---VW 412 A +E + + SD++S+ S+KE+E + + DK E+ +E L V Sbjct: 1598 TDEAAFEPDYNE-SDSESN------VSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQ 1650 Query: 413 IRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTK 472 + + ++++ S S +R E S+++K K + + K Sbjct: 1651 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1710 Query: 473 LDEDLESSSESECESDE 489 + +E E E + Sbjct: 1711 KKHKKHAGTEVELEKSQ 1727 Score = 38.1 bits (87), Expect = 0.059 Identities = 62/317 (19%), Positives = 119/317 (37%), Gaps = 29/317 (9%) Query: 211 PLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYD 270 P+ KA E + K + + G + S +E + + ++ + + DY Sbjct: 1024 PIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQET--KPVKEEKVKKDYS 1081 Query: 271 RGRTPSRHRSYERSRERERERHRHRDN----RRSPSLERSYKKEYKRSGRSYGLSVVPEP 326 + + + E ++ E+++ DN R+ + E+ K+++ S V E Sbjct: 1082 KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141 Query: 327 AGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTS 386 +P+ E P + ++ +P+++ K R +K ++N S+ Sbjct: 1142 VKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN-------- 1193 Query: 387 IKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVG--------- 437 KEP E + + + ++E +K R SS +D S+ G Sbjct: 1194 --TKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK 1251 Query: 438 TSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSS 497 T R + EE A+ + P++K D+D ESE E D ST SS Sbjct: 1252 TDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKD---DFESE-EEDVKSTQPISS 1307 Query: 498 DSEVFDVIAEIKRKKAH 514 + VI + K ++ Sbjct: 1308 VGKPASVIKNVSTKPSN 1324 Score = 36.2 bits (82), Expect = 0.22 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 14/71 (19%) Query: 146 MPPPSMPHPPPPPVMPQQV---------NYQYP---PGYSHHNFPPPSFNSFQNNPSSFL 193 +PPP P PPP P++ + + Q P P S P PS +S +N SS Sbjct: 336 LPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLA 395 Query: 194 P--SANNSSSP 202 P S N SS+P Sbjct: 396 PPVSGNPSSAP 406 Score = 33.5 bits (75), Expect = 1.4 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 29 PSAPSFRPQNLRLLHP-QQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPM-- 85 P P RP R L P + P+ Q +P P T+ S PAP+ + PP+ Sbjct: 341 PPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSG 400 Query: 86 -PPSAQGPLP 94 P SA P+P Sbjct: 401 NPSSAPAPVP 410 Score = 30.8 bits (68), Expect = 9.3 Identities = 51/237 (21%), Positives = 88/237 (37%), Gaps = 27/237 (11%) Query: 320 LSVVPEPAGCTPEL---PGEIIKNTDSWAPPLEIVNH--RSPSREKKRARWEEEKDRWSD 374 +S V +PA + P I+K + + P E + + S E + + K+ S Sbjct: 1305 ISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASS 1364 Query: 375 NQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYS----------S 424 + KD++Y+ ++++ PE+ E+E L R N+ S S Sbjct: 1365 EKGKTKDRDYSVLEKENPEKRKNSTQPEKESNL-----DRLNEQGNFKSLSQSSKEARTS 1419 Query: 425 DPMDQVGDSTVVGTSRLRDL---YDKFEEELGSRQ-EKAKAARPPWEPPKTKLDEDLESS 480 D D S+ + RD YD E R+ EK + R P + K D S Sbjct: 1420 DKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNK---DSASG 1476 Query: 481 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCK 537 +++ + D + DS+ + RK +D N+ + D CK Sbjct: 1477 QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533 >gi|119226260 calcium homeostasis endoplasmic reticulum protein [Homo sapiens] Length = 916 Score = 75.9 bits (185), Expect = 3e-13 Identities = 90/309 (29%), Positives = 105/309 (33%), Gaps = 63/309 (20%) Query: 80 PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP-VPPCF--PPMPPPMPCPNNPPVPGAP 136 PF PP +GP PP P F H F PP F PP P P Sbjct: 513 PFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFD 572 Query: 137 PGQGTFPFMMPPPS------MPHPP----PPPVMPQQVNYQYPP-------------GYS 173 QG FP M PP MPHP PP PQ ++ PP G Sbjct: 573 YPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPP 632 Query: 174 HHNFPPPSFNS---FQNNPSSFLPSANNSSSPHFRHLPP----YPLPKAPSER--RSPER 224 H N PS + + P+ + ++ L P P P PSER + E Sbjct: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692 Query: 225 LKHYDDHRHRDHSHG--------------RGERHRSLDRRERGRSPDRRRQDSRYRSD-- 268 H +S G R R + ++R G S R R SR RS Sbjct: 693 FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSR 752 Query: 269 -----------YDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRS 317 Y R R+ S RSY RSR R R R R RS S RS K Y R Sbjct: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR-SSRSRSRSQSRSRSKSYSPGRRR 811 Query: 318 YGLSVVPEP 326 S P P Sbjct: 812 RSRSRSPTP 820 Score = 44.3 bits (103), Expect = 8e-04 Identities = 71/292 (24%), Positives = 91/292 (31%), Gaps = 63/292 (21%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR--PP 101 P PP P P+T +S P +P ++ P+A GP P P PP Sbjct: 357 PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPP 416 Query: 102 FPNHQMRHPFPVPPC---FPPMPPPMPCPNNPPVPGAPP-------------------GQ 139 P PV P PP PP P P P PP GQ Sbjct: 417 NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGP-PHCPPWNNSHEGMWGEQRGDPGWNGQ 475 Query: 140 GTFP------------FMMPPPSMPHPPP-------PPV---MPQQVNYQYPPGYSHHNF 177 P F P S PP PP P +PP H F Sbjct: 476 RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQF 535 Query: 178 -PPPSFNSFQNNPSSFL----PSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHR 232 PP ++F P F+ P + P + H YP P+E P H+ HR Sbjct: 536 NQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPH---HHPGHR 592 Query: 233 H-----RDHSHGRGERHRSL---DRRERGRSPDRRRQDSRYRSDYDRGRTPS 276 +H G +H G+ P RRQ + + D P+ Sbjct: 593 MPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPN 644 Score = 42.0 bits (97), Expect = 0.004 Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 82 PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141 PPP PP A P P P P Q PP P P P A +G Sbjct: 356 PPPAPPPAPAPAPAIP-----PTTQPDD--SKPPIQMPGSSEYEAPGGVQDPAAAGPRGP 408 Query: 142 FPFMMPPPSMP--HPPPPPVMP--QQVNYQYPPGYSHHNFPPPSFNSFQNN 188 P PP+ P P PV P QQ + PP Y HH PP + N+ Sbjct: 409 GPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPP-YPHHQGGPPHCPPWNNS 458 Score = 33.5 bits (75), Expect = 1.4 Identities = 25/94 (26%), Positives = 33/94 (35%), Gaps = 17/94 (18%) Query: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSH-----------HNF 177 PP P PP P +PP + P PP+ MP Y+ P G H+ Sbjct: 355 PPPPAPPPAPAPAP-AIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQ 413 Query: 178 PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211 PP+ + + P P PPYP Sbjct: 414 IPPNKPPWFDQPHPVAPWGQQQPPEQ----PPYP 443 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 75.1 bits (183), Expect = 4e-13 Identities = 62/187 (33%), Positives = 78/187 (41%), Gaps = 24/187 (12%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPA----PNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR 99 P PPVQ + PP++P + S +P P+ P P PP PP + PP Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727 Query: 100 PPFPNHQMRHPFPVPPCFPPMPPPM-PCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--- 155 PP ++ P P PP PPM P P P PP+ APP Q PP S+P P Sbjct: 728 PPLAAPPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMSPLAK 783 Query: 156 PPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKA 215 PPP P + P PP SF + F PSA+ SP P P+A Sbjct: 784 PPPQAPPAL---ATPPLQALPSPPASF----PGQAPFSPSASLPMSP-----LATPPPQA 831 Query: 216 PSERRSP 222 P +P Sbjct: 832 PPVLAAP 838 Score = 67.4 bits (163), Expect = 9e-11 Identities = 69/247 (27%), Positives = 86/247 (34%), Gaps = 32/247 (12%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR-------PDFVPF 81 P +PS P + PP+Q PP++P + S +P P PP P P Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743 Query: 82 PPPMPPSAQGP--------LPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVP 133 PPM PSA P PP + P P P PP P PP + P +P Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP--PQAPPALATPPLQALP 801 Query: 134 GAP---PGQGTF----PFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQ 186 P PGQ F M P + P P PPV+ + Q PP PP+ + Q Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPS-------PPASPTLQ 853 Query: 187 NNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRS 246 P + S S L P P P R L D H + E R Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913 Query: 247 LDRRERG 253 D G Sbjct: 914 YDSGPEG 920 Score = 65.5 bits (158), Expect = 3e-10 Identities = 64/206 (31%), Positives = 76/206 (36%), Gaps = 32/206 (15%) Query: 47 PPVQYQYEPPSAPSTTFSNSP---APNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF- 102 PP+Q PP++P + +P APN L PF PP P Q P P P PP Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVS 686 Query: 103 ---------PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP------ 147 P P VPP PP PPM P+ P P APP P +P Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPS-PPASPPM-SPSATPPPQAPPPLAAPPLQVPPSPPAS 744 Query: 148 PPSMPHPPPPPVMPQQV---NYQYPPG------YSHHNFPPPSF-NSFQNNPSSFLPSAN 197 PP P PPP +P + Q PP S PPP + P LPS Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804 Query: 198 NSSSPHFRHLPPYPLPKAPSERRSPE 223 S P LP +P P+ Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQ 830 Score = 57.4 bits (137), Expect = 9e-08 Identities = 58/189 (30%), Positives = 65/189 (34%), Gaps = 56/189 (29%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQP-PVQYQYEPPSAPSTTFSNSPAPNFL 72 P R P RG P AP+ HP QP P Q P P Sbjct: 252 PARSGPSARG----TPRAPA---------HPSQPKPKGLQALRP------------PQVT 286 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP--------VPPCFPPMPP-P 123 PPR D P A GPL P+ P P+ P P +P PP PP Sbjct: 287 PPRKDAAP--------ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338 Query: 124 MPCPNNPPVPGAPPGQGTFPF------MMPPPSMPHPP--PPPVMPQQVNYQYPPGYSHH 175 P P PP P APP T P PPSM PP PP + PP H Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL-----QTIPPIQVPH 393 Query: 176 NFPPPSFNS 184 + PS + Sbjct: 394 SLTSPSLQA 402 Score = 52.0 bits (123), Expect = 4e-06 Identities = 62/217 (28%), Positives = 75/217 (34%), Gaps = 47/217 (21%) Query: 43 HPQQPPVQYQYEPP-----SAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPL---- 93 H Q P+ PP S + PA PP + PP +A PL Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557 Query: 94 ---PPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT-----FPFM 145 PPCP P P P PP P P P PP +PP QG P Sbjct: 558 LETPPCPA--PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615 Query: 146 MPPPSMPH----------PPP---PPVMPQQV-NYQYPPGYSHHNF-----PPPS----- 181 PPP P P P PP+ P + Q P + H PPPS Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675 Query: 182 -FNSFQNNPSSFLPSAN-NSSSPHFRHLPPYPLPKAP 216 F+ + P S PSA S +P PP +P +P Sbjct: 676 PFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSP 710 Score = 39.7 bits (91), Expect = 0.020 Identities = 62/253 (24%), Positives = 79/253 (31%), Gaps = 65/253 (25%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR---PDFVPFPP-P 84 PS P P L P PP PS P+T S +P PP P PP Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTL--PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390 Query: 85 MPPSAQGP---LPPCPIRPPF---------PNHQMRHPF-------------------PV 113 +P S P PP P+ P Q H F Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450 Query: 114 PPCFPPMPPPMPCPNNPPV-----PGAPPGQGTF---PFMMPPPSMPHPPPPPVMPQQVN 165 PP PP+ P+ P +PP+ P P P H P P+ + Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS----S 506 Query: 166 YQYPPGYSHHNFPPPSFNS---------FQNNPSSFLPSANNSS----SPHFRHLP---P 209 PP + + PPS + +N PS P +S +PH P P Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566 Query: 210 YPLPKAPSERRSP 222 PL PS +P Sbjct: 567 CPLQAPPSPLTTP 579 Score = 32.0 bits (71), Expect = 4.2 Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 37/198 (18%) Query: 31 APSFRPQNLRLLHPQQPPVQYQYEPPSAPS--TTFSNSPAPNFLPPRPDFVPFPPPMPPS 88 APS RP+ PP + + S+ S +T SPA P + P S Sbjct: 193 APSARPR---------PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 89 AQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPP 148 + P+ P + P P P P P P PP + P + P Sbjct: 244 SSAT----PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299 Query: 149 PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLP 208 S P P P G PPP +N ++ LP+ S P Sbjct: 300 SSSPLATPS-----------PSGTKARPVPPP------DNAATPLPATLPPSPP-----L 337 Query: 209 PYPLPKAPSERRSPERLK 226 PLP AP +P L+ Sbjct: 338 ATPLPLAPPSPSAPPSLQ 355 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 74.7 bits (182), Expect = 6e-13 Identities = 98/389 (25%), Positives = 142/389 (36%), Gaps = 76/389 (19%) Query: 21 GRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVP 80 G G R S + R + P + PS P T SP+P PPR P Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP-APPPRRRRTP 573 Query: 81 FPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQG 140 P PP + P PP R P P R+ P+ + P PPP +PP PP + Sbjct: 574 TP---PPRRRTPSPPPRRRSPSPR---RYSPPIQRRYSPSPPPKRRTASPP---PPPKRR 624 Query: 141 TFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSS 200 P P + H PPP V + P S S + ++PS A S Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS-------SKHRKGSSPSRSTREA-RSP 676 Query: 201 SPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRR 260 P+ RH P P P+AP SP + RR SP RR+ Sbjct: 677 QPNKRH-SPSPRPRAPQTSSSPPPV-----------------------RRGASSSPQRRQ 712 Query: 261 QDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL 320 S PS SR E ++ + SPS + +R S + Sbjct: 713 SPS-----------PSTRPIRRVSRTPEPKKIK---KAASPS-----PQSVRRVSSSRSV 753 Query: 321 SVVPEPAGCTPELPGEIIKN---TDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQS 377 S PEPA P P +++ + +W+P + + +SP+ R SD + Sbjct: 754 SGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP-------SPSPPRNSDQEG 806 Query: 378 SGKDKNYTSIKEKEPEETMPDKNEEEEEE 406 GK K K+K+ ++ DK ++ ++ Sbjct: 807 GGKKK-----KKKKDKKHKKDKKHKKHKK 830 Score = 49.7 bits (117), Expect = 2e-05 Identities = 58/252 (23%), Positives = 93/252 (36%), Gaps = 17/252 (6%) Query: 230 DHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPS-RHRSYERSRERE 288 D ++ S + ER RS RR + RSP RR+ S R + R + S RHR+ RS Sbjct: 155 DKEEKESSREKRERSRS-PRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213 Query: 289 RERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSV-----VPEPAGCTPELPGEIIKNTDS 343 E+ PS++ + + S L V +PEP +PE + K + Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273 Query: 344 WAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEE 403 P RS S+ + R R + + ++Y+ + P + Sbjct: 274 TRP-----RSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP 328 Query: 404 EEELLKPVWIRCTHS---ENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK 460 + P R + S SS + G S+ +SR R K + S K + Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLS--GSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386 Query: 461 AARPPWEPPKTK 472 P PP+ + Sbjct: 387 RLSPSASPPRRR 398 Score = 48.5 bits (114), Expect = 4e-05 Identities = 66/298 (22%), Positives = 94/298 (31%), Gaps = 64/298 (21%) Query: 19 PRGRGGHGARPS------APSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFL 72 PRGR P +PS P R P PP + PS P S SP Sbjct: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPP---RRRTPSPPPRRRSPSPRRYSP 598 Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPP---CFPPMPPPMPCPNN 129 P + + P PPP +A P PP P P + R PP P P ++ Sbjct: 599 PIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658 Query: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPP-------GYSHHNFPPPSF 182 G+ P + T P P+ H P P Q + PP P PS Sbjct: 659 KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718 Query: 183 NSFQN----------------NPSSFL----------------------PSANNSSSPHF 204 + +P S PS S SP Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778 Query: 205 RHLPPYPLPKAPSERRSPERLKHYDDH-------RHRDHSHGRGERHRSLDRRERGRS 255 P P+ KA S SP ++ D + +D H + ++H+ + ++ ++ Sbjct: 779 NWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKA 836 Score = 44.7 bits (104), Expect = 6e-04 Identities = 53/203 (26%), Positives = 77/203 (37%), Gaps = 55/203 (27%) Query: 226 KHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSR 285 K +D RD + E+ S ++RER RSP RR+ R+PS R R Sbjct: 146 KQDEDKDKRD----KEEKESSREKRERSRSPRRRKS-----------RSPSPRRRSSPVR 190 Query: 286 ERERERH-----RHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKN 340 RER+R RHR RSP S PE TPELP +K Sbjct: 191 -RERKRSHSRSPRHRTKSRSP-------------------SPAPEKKEKTPELPEPSVKV 230 Query: 341 TD-------------SWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSI 387 + P I + PS E K ++ E+EK++ + +S + K+ + Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPE-KNSKKEKEKEK-TRPRSRSRSKSRSRT 288 Query: 388 KEKEPEETMPDKNEEEEEELLKP 410 + + P T P + P Sbjct: 289 RSRSPSHTRPRRRHRSRSRSYSP 311 Score = 43.9 bits (102), Expect = 0.001 Identities = 56/221 (25%), Positives = 82/221 (37%), Gaps = 31/221 (14%) Query: 209 PYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPD----RRRQDSR 264 P P PK PS ++ ++ K + R R S + R R RSP RRR SR Sbjct: 252 PIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS------RTRSRSPSHTRPRRRHRSR 305 Query: 265 YRSDYDRGRTPSRHRSYERSRERERE-----RHRHRDN--RRSPSLERSYKKEYKRSGRS 317 RS R R R R R R R RHR + RR S S S Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS 365 Query: 318 YGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHR-----SPSREKKRARWEEEKDRW 372 S +P T P + + + S +PP HR +P + + + ++ +R Sbjct: 366 RSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHRPSPPATPPPKTRHSPTPQQSNRT 423 Query: 373 -------SDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEE 406 S ++SGK + +++E P + E E Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE 464 Score = 41.6 bits (96), Expect = 0.005 Identities = 60/268 (22%), Positives = 91/268 (33%), Gaps = 31/268 (11%) Query: 121 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF--- 177 P P P P P + T P MPPP PV ++ + G S + Sbjct: 311 PRRRPSPRRRP----SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366 Query: 178 -------PPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDD 230 PP +S PSA S P RH P P P R SP + Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSA---SPPRRRHRPSPPATPPPKTRHSPTPQQSNRT 423 Query: 231 HRHR-----DHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSR 285 + R + G+ +H+ ++RE + R+ S+ D+G + S ++ R Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR 483 Query: 286 ERERERHRHRDNRRSPSL------ERSYKKE---YKRSGRSYGLSVVPEPAGCTPELPGE 336 + R+ + + S S +RS+ K +R S S P P E Sbjct: 484 QYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543 Query: 337 IIKNTDSWAPPLEIVNHRSPSREKKRAR 364 + PP SP+ +R R Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRR 571 Score = 40.0 bits (92), Expect = 0.015 Identities = 65/267 (24%), Positives = 91/267 (34%), Gaps = 51/267 (19%) Query: 261 QDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL 320 ++S+ + ++ R SR RS RSR R R R RR S RSY + S R Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR-- 320 Query: 321 SVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGK 380 P P TP PP RSP R ++R+ S + SS Sbjct: 321 ---PSPRRRTP---------PRRMPPPPRHRRSRSPVRRRRRS-----SASLSGSSSSSS 363 Query: 381 DKNYTSIKEKEPEETM--PDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGT 438 S +K P+ T P K P R H + ++ P T + Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP---RRRHRPSPPATPPPKTRHSPTPQQS 420 Query: 439 SRLRD---------LYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSS-------- 481 +R R K + G+ EK ++ P +P K +L E E Sbjct: 421 NRTRKSRVSVSPGRTSGKVTKHKGT--EKRESPSPAPKPRKVELSESEEDKGGKMAAADS 478 Query: 482 --------ESECESDEDSTCSSSSDSE 500 +S DS SSSS+ E Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDE 505 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.076 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.076 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.076 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 29/213 (13%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPP 87 RP +P+ + + P PP PP PS ++S + P VP PPP P Sbjct: 307 RPQSPATGRTPV-FVSPTPPP-----PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360 Query: 88 SA-QGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMM 146 +A Q P P P P + HP P PP+ PP+ P +PPV A P T P Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAP-----PPIAPPLVQP-SPPVARAAPVCETVPVHP 414 Query: 147 PP----PSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSP 202 P +P PPPPP +P PPG + P + + + PS P+ + + P Sbjct: 415 LPQGEVQGLPPPPPPPPLP-------PPGIRPSS--PVTVTALAHPPSGLHPTPSTAPGP 465 Query: 203 HFRHLPPYP---LPKAPSERRSPERLKHYDDHR 232 H +PP P + A +R P L D R Sbjct: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498 Score = 37.7 bits (86), Expect = 0.076 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 55/159 (34%) Query: 113 VPPCFPPMPPPM---------------------------------------PCPNNPPVP 133 V P PP PPPM P P PP+P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 134 GAPPGQGTFPFM--MPPPSMPHPPPPP--------VMPQQVNYQYPPGYSHHNFPPPSFN 183 A M PPP +P PPPPP V P Q PG H PP + Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392 Query: 184 SFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSP 222 Q +P P A ++P +P +PLP+ + P Sbjct: 393 LVQPSP----PVAR--AAPVCETVPVHPLPQGEVQGLPP 425 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 73.6 bits (179), Expect = 1e-12 Identities = 69/246 (28%), Positives = 88/246 (35%), Gaps = 63/246 (25%) Query: 19 PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPP-------------SAP--STTF 63 P GGHG P + + P PP+ PP S P S + Sbjct: 402 PSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461 Query: 64 SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFP-PMPP 122 +PP P + PPP PPS Q P PP PP+ Q + P P PP Sbjct: 462 RLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521 Query: 123 PMPCPNN-------------PP----------VPGAPPGQGTFPFMMP---------PPS 150 P+P N PP PGAP QG P M+P PP Sbjct: 522 PLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN-PTMVPLPPGVQPPLPPG 580 Query: 151 MPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPY 210 P PPPPP PPG + + PP +PS+F+ + +PP+ Sbjct: 581 APPPPPPP----------PPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVA----GMPPF 626 Query: 211 PLPKAP 216 +P AP Sbjct: 627 GMPPAP 632 Score = 48.5 bits (114), Expect = 4e-05 Identities = 56/182 (30%), Positives = 65/182 (35%), Gaps = 46/182 (25%) Query: 13 HPGRGC--PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAP----------- 59 H G+G P G P PS +P P P Q Q +PP P Sbjct: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-GPLPPWQQQQQQPPPPPPPSSSMASSTP 522 Query: 60 ------STTFSNSPAPNFLPP--RPDFVPFPPPMPPSAQG-----PLPPCPIRPPFPNHQ 106 +TT + S +PP + P P QG PLPP ++PP P Sbjct: 523 LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP--- 578 Query: 107 MRHPFPVPPCFPPMPPP-----MPCPNNPPVPGAPPG-----QGTFPFMMPPPSMPHPPP 156 P PP PP PPP M P PP P P G MPP MP PP Sbjct: 579 ---PGAPPP--PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633 Query: 157 PP 158 PP Sbjct: 634 PP 635 Score = 38.5 bits (88), Expect = 0.045 Identities = 45/139 (32%), Positives = 52/139 (37%), Gaps = 19/139 (13%) Query: 46 QPPVQYQYEPPSAPSTT-FSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPF-- 102 + PV S P+TT +++P P P PPP S PP P Sbjct: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP-----PPPSLMSTTQSRPPWMNSGPSES 376 Query: 103 -PNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSM-PHPPPPPVM 160 P H M P P P P P P+ G P Q P PPP M P PPP Sbjct: 377 RPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN-PNGPPPPWMQPPPPPMNQG 435 Query: 161 PQQVNYQYPPGYSHHNFPP 179 P +PPG HH PP Sbjct: 436 P------HPPG--HHGPPP 446 Score = 36.6 bits (83), Expect = 0.17 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 8/69 (11%) Query: 69 PNFLPPRPDFVPFPPPMPPS-------AQGPLPPCPIRPP-FPNHQMRHPFPVPPCFPPM 120 P PP P P PPP PP A P PP P+ P F +PP P Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPP 630 Query: 121 PPPMPCPNN 129 PP P P N Sbjct: 631 APPPPPPQN 639 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 72.8 bits (177), Expect = 2e-12 Identities = 66/211 (31%), Positives = 77/211 (36%), Gaps = 49/211 (23%) Query: 55 PPSAP----STTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGP------LPPCPIRP---- 100 PPSAP S+ S P P PP FPPP+PP P +PP P+ P Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPPPGS----FPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272 Query: 101 -----------PFPNHQMRHPFPVPPCFPPMP--PPMPCPNNPP-----VPGAPPGQGTF 142 P H HP P PP P P M ++ P PPG G Sbjct: 273 HGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332 Query: 143 PFMMPPPSMPHPPPPPV-MPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201 P PPP MPHP PPP+ MP + PP S P P P +P + Sbjct: 333 PPPRPPPGMPHPGPPPMGMPP----RGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGP 388 Query: 202 PHFRHL--------PPYPLPKAPSERRSPER 224 P PP P P+ P R P R Sbjct: 389 PRPPPYGYQRGPLPPPRPTPRPPVPPRGPLR 419 Score = 62.4 bits (150), Expect = 3e-09 Identities = 50/150 (33%), Positives = 59/150 (39%), Gaps = 15/150 (10%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLP 73 PG G P G G P P P HP +Q + P + P P Sbjct: 281 PGAGHP-GHGHSHPHPFPPGGMP------HPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP 333 Query: 74 PRPDFVPFPPP-MPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPV 132 P P PPP MP P+ P PPF + M HP P+PP PPP+ P+ Sbjct: 334 P-----PRPPPGMPHPGPPPMGMPPRGPPFGS-PMGHPGPMPPHGMRGPPPLMPPHGYTG 387 Query: 133 PGAPPGQGTFPFMMPPP-SMPHPPPPPVMP 161 P PP G +PPP P PP PP P Sbjct: 388 PPRPPPYGYQRGPLPPPRPTPRPPVPPRGP 417 Score = 58.5 bits (140), Expect = 4e-08 Identities = 49/153 (32%), Positives = 53/153 (34%), Gaps = 28/153 (18%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQ------------- 90 P PP + PPSA T + P P P F P P P +Q Sbjct: 264 PPMPPGAAGHGPPSA-GTPGAGHPGHGHSHPHP-FPPGGMPHPGMSQMQLAHHGPHGLGH 321 Query: 91 ---GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147 GP PP P M HP P P PP PP P P P P G P +MP Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMP 381 Query: 148 PPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP 180 P PP PP P GY PPP Sbjct: 382 PHGYTGPPRPP----------PYGYQRGPLPPP 404 Score = 48.1 bits (113), Expect = 6e-05 Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 24/145 (16%) Query: 88 SAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMP 147 +AQ PL RP HQ+ P PP P P + P PG PP G+FP +P Sbjct: 196 AAQNPLSQAD-RP----HQLFADAPPPPS-APNPVVSSLGSGLPPPGMPP-PGSFPPPVP 248 Query: 148 PP-SMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRH 206 PP ++P P PP MP PPG + H PS+ P A + H H Sbjct: 249 PPGALP-PGIPPAMPPP---PMPPGAAGH-----------GPPSAGTPGAGHPGHGH-SH 292 Query: 207 LPPYPLPKAPSERRSPERLKHYDDH 231 P+P P S +L H+ H Sbjct: 293 PHPFPPGGMPHPGMSQMQLAHHGPH 317 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 72.4 bits (176), Expect = 3e-12 Identities = 72/248 (29%), Positives = 89/248 (35%), Gaps = 50/248 (20%) Query: 35 RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQG--P 92 RP R P PP + PS P + S+ P PP P P PPP+PPS+ G Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP---PPPPPSRPGPPPLPPSSSGNDE 330 Query: 93 LPPCPIR--------PPFPNHQMRHPFPVPPC-------------FPPMPPPMPCPNNPP 131 P P R PP P+ P P PP P+PPP P N Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390 Query: 132 VPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSF---NSFQNN 188 A P P S P PP+ P + + PP PPPS N FQ++ Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP------PPPSTSIRNGFQDS 444 Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLD 248 P + P LPP P P + + P +L R E + Sbjct: 445 PCEDEWESRFYFHP-ISDLPP-PEPYVQTTKSYPSKL-------------ARNESRSGSN 489 Query: 249 RRERGRSP 256 RRERG P Sbjct: 490 RRERGAPP 497 Score = 67.8 bits (164), Expect = 7e-11 Identities = 76/246 (30%), Positives = 92/246 (37%), Gaps = 62/246 (25%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYE--PPSAPSTT--FSNSPAP 69 PGR P GH + P PQ R+ P +P V + + PP PST +SP Sbjct: 147 PGR-FPVPSPGHRSGPP----EPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200 Query: 70 NFLPP------RPDFVPFPPPMPPSA----------QGPLP---PCPIRPPFPNHQMRHP 110 PP +P P PPP P + Q PL P RPP P R Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL 260 Query: 111 FPVPPCFPP------------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158 PP PP +PPP P N PPVP P + PPP P PPP Sbjct: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320 Query: 159 VMPQQVNYQYPPGYSHHNFPP--PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 + PP S ++ P P N ++ + LPS S PLP P Sbjct: 321 L---------PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------PLPPPP 361 Query: 217 SERRSP 222 SER P Sbjct: 362 SERPPP 367 Score = 40.0 bits (92), Expect = 0.015 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 29/160 (18%) Query: 64 SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPP 123 S P LPP P PPS G P P P H+ PP P Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-----PSPGHRSG---------PPEPQR 166 Query: 124 MPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 P PP P G+ P +PPP P P P PG P P+ Sbjct: 167 NRMP--PPRPDV----GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220 Query: 184 SFQNNPSSFL------PSANNSSSPHFRHLPPYPLPKAPS 217 F N + L S +SSSP F + P PLP PS Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSP-FSNRP--PLPPTPS 257 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 72.4 bits (176), Expect = 3e-12 Identities = 72/248 (29%), Positives = 89/248 (35%), Gaps = 50/248 (20%) Query: 35 RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQG--P 92 RP R P PP + PS P + S+ P PP P P PPP+PPS+ G Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP---PPPPPSRPGPPPLPPSSSGNDE 330 Query: 93 LPPCPIR--------PPFPNHQMRHPFPVPPC-------------FPPMPPPMPCPNNPP 131 P P R PP P+ P P PP P+PPP P N Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390 Query: 132 VPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSF---NSFQNN 188 A P P S P PP+ P + + PP PPPS N FQ++ Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP------PPPSTSIRNGFQDS 444 Query: 189 PSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLD 248 P + P LPP P P + + P +L R E + Sbjct: 445 PCEDEWESRFYFHP-ISDLPP-PEPYVQTTKSYPSKL-------------ARNESRSGSN 489 Query: 249 RRERGRSP 256 RRERG P Sbjct: 490 RRERGAPP 497 Score = 67.8 bits (164), Expect = 7e-11 Identities = 76/246 (30%), Positives = 92/246 (37%), Gaps = 62/246 (25%) Query: 14 PGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYE--PPSAPSTT--FSNSPAP 69 PGR P GH + P PQ R+ P +P V + + PP PST +SP Sbjct: 147 PGR-FPVPSPGHRSGPP----EPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200 Query: 70 NFLPP------RPDFVPFPPPMPPSA----------QGPLP---PCPIRPPFPNHQMRHP 110 PP +P P PPP P + Q PL P RPP P R Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL 260 Query: 111 FPVPPCFPP------------MPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158 PP PP +PPP P N PPVP P + PPP P PPP Sbjct: 261 DDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320 Query: 159 VMPQQVNYQYPPGYSHHNFPP--PSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 + PP S ++ P P N ++ + LPS S PLP P Sbjct: 321 L---------PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------PLPPPP 361 Query: 217 SERRSP 222 SER P Sbjct: 362 SERPPP 367 Score = 40.0 bits (92), Expect = 0.015 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 29/160 (18%) Query: 64 SNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPP 123 S P LPP P PPS G P P P H+ PP P Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-----PSPGHRSG---------PPEPQR 166 Query: 124 MPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFN 183 P PP P G+ P +PPP P P P PG P P+ Sbjct: 167 NRMP--PPRPDV----GSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220 Query: 184 SFQNNPSSFL------PSANNSSSPHFRHLPPYPLPKAPS 217 F N + L S +SSSP F + P PLP PS Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSP-FSNRP--PLPPTPS 257 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 72.0 bits (175), Expect = 4e-12 Identities = 45/108 (41%), Positives = 52/108 (48%), Gaps = 17/108 (15%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 PP AP+ P P LP P P PP + PP P PP P Q + P P P Sbjct: 1422 PPLAPAAAV---PGPPPLPGLPSANSNGTPEPPLLEEKPPPTP--PPAPTPQPQPPPPPP 1476 Query: 115 PCFP--PMPPPM--PCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158 P P P PPP+ P P++PP P PP PPP+MP PPPPP Sbjct: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPP--------PPPPAMPSPPPPP 1516 Score = 64.7 bits (156), Expect = 6e-10 Identities = 53/164 (32%), Positives = 64/164 (39%), Gaps = 21/164 (12%) Query: 60 STTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCF-- 117 S+ S P P+ P PP+ P+A P PP P+ P P+ P PP Sbjct: 1399 SSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPP-PL-PGLPSANSNGT-PEPPLLEE 1455 Query: 118 --PPMPPPMPCPNNPPVPGAPPGQGTFP----FMMPPPSMPHPPP-PPVMPQQVNYQYPP 170 PP PPP P P P P PP Q P + P PS P PPP PP P + PP Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515 Query: 171 GYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPK 214 PPP+ P P+A + P P L K Sbjct: 1516 -------PPPAAAPLAAPPEE--PAAPSPEDPELPDTRPLHLAK 1550 Score = 64.7 bits (156), Expect = 6e-10 Identities = 43/119 (36%), Positives = 51/119 (42%), Gaps = 16/119 (13%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMP-PSAQGPLPPCPIRPPF 102 P PP+ P PS + +P P L +P P PPP P P Q P PP P +P Sbjct: 1431 PGPPPL------PGLPSANSNGTPEPPLLEEKPP--PTPPPAPTPQPQPPPPPPPPQPAL 1482 Query: 103 PNHQMRHPFPVPPCFPPMPPPMPCPNNP--PVPGAPPGQGTFPFMMPP--PSMPHPPPP 157 P+ P P P PPP+P P P P P PP P PP P+ P P P Sbjct: 1483 PSPP---PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538 Score = 50.1 bits (118), Expect = 1e-05 Identities = 34/94 (36%), Positives = 38/94 (40%), Gaps = 10/94 (10%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P P Q Q PP P SP P + P P P PPP+PP P P P PP P Sbjct: 1462 PPAPTPQPQPPPPPPPPQPALPSPPP-LVAPTPSSPP-PPPLPPP---PPPAMPSPPPPP 1516 Query: 104 NHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPP 137 P P PP P P P +P +P P Sbjct: 1517 -----PPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545 Score = 43.1 bits (100), Expect = 0.002 Identities = 32/94 (34%), Positives = 37/94 (39%), Gaps = 18/94 (19%) Query: 125 PCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNS 184 P P + GA PG TFP + YQ+P + FP PS S Sbjct: 125 PGPTELFISGALPGSSTFPSSSALSA---------------YQHPASFGSRPFPVPSSLS 169 Query: 185 FQNNPSSFLPSANNSSSPH-FRHLPPYPLPKAPS 217 Q+ P F P AN SPH HL P P PS Sbjct: 170 LQDPP--FSPPANGLLSPHDVLHLKPSQAPTVPS 201 Score = 42.7 bits (99), Expect = 0.002 Identities = 50/175 (28%), Positives = 64/175 (36%), Gaps = 31/175 (17%) Query: 52 QYEPPSAPSTTFSNSPAPNFL------PPRPDFVPFPPP-MPPSAQGPLP-PCPIRPPFP 103 Q PP P T S P P+ L P P +P PPP + PS P P P Sbjct: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820 Query: 104 NHQMRHPFPVPPCFPPMPPPMPCPNNPPVP----------GAPPGQGTFPFMMPPPSMPH 153 H + P P PPP P P PP+P G P + P + P S+ Sbjct: 821 VHLLE---PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS-PRLRPEESL-- 874 Query: 154 PPPPPVMPQQVN--YQYPPGYSHHNFPPPSFNSFQNNPSSFL--PSANNSSSPHF 204 PP M + + PP PP NS +P+ PS + +P F Sbjct: 875 -DPPGAMQELLGALEPLPPAPGDTGVGPP--NSEGKDPAGAYRSPSPQGTKAPRF 926 Score = 37.4 bits (85), Expect = 0.100 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 128 NNPPVPGAPPGQGTFPFMM-----PPPSMPHPPPPPVMPQQVNYQYPP 170 + PPVP GQ P PPP P PPP P P++ + PP Sbjct: 1668 HRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPP 1715 Score = 35.0 bits (79), Expect = 0.50 Identities = 48/176 (27%), Positives = 61/176 (34%), Gaps = 29/176 (16%) Query: 60 STTFSNSPAPNFLPPRPDFV--PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCF 117 S+TF +S A + F PFP P S Q P P PP + + P V Sbjct: 139 SSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDP----PFSPPA--NGLLSPHDVLHLK 192 Query: 118 PPMPPPMPCPNNPP--VPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHH 175 P P +P G G PP P PP PP P+ + Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHL----------- 241 Query: 176 NFPPPSFNSFQNNPSSFLPSANNSSSP---HFRHLPPYPLPKAPSERRSPERLKHY 228 P FN + SS +A SSP +F P P P + R +KHY Sbjct: 242 ---PTQFNLLAS--SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHY 292 Score = 34.3 bits (77), Expect = 0.85 Identities = 39/135 (28%), Positives = 44/135 (32%), Gaps = 24/135 (17%) Query: 82 PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141 PPP PP+ P CP R + P P PP +P N G Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPET----PGLGLDPNKPPELPSTVNAEPLGLIQSG-- 1033 Query: 142 FPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSS 201 P PP P PPPPP P P F S P L +SS Sbjct: 1034 -PHQAAPPPPPPPPPPPA---------PASEPKGGLTSPIFCS--TKPKKLL----KTSS 1077 Query: 202 PHF--RHLPPYPLPK 214 H R PP+ PK Sbjct: 1078 FHLLRRRDPPFQTPK 1092 Score = 32.7 bits (73), Expect = 2.5 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 10/41 (24%) Query: 118 PPMPPPMPCPNNPPVPGAPPGQGTFPFMMPP--PSMPHPPP 156 PP+ PP P + P G P PP P++PHPPP Sbjct: 1305 PPLSPPKSVPPSVPARGLQP--------QPPATPAVPHPPP 1337 Score = 32.0 bits (71), Expect = 4.2 Identities = 35/135 (25%), Positives = 43/135 (31%), Gaps = 9/135 (6%) Query: 32 PSFRPQNLRLLHPQQPPVQYQYEPPSAPSTT-FSNSPAPNFLPPRPDFVPFPPPMPPSAQ 90 P F P LL P + P+ PS+ F L P PP P Sbjct: 173 PPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPP 232 Query: 91 GPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM-----PCPNNPPVPGAPPGQGTF--P 143 P PP P P + + P + P PP A P Q T Sbjct: 233 DPPPP-PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291 Query: 144 FMMPPPSMPHPPPPP 158 + P + P PPPPP Sbjct: 292 YQRPASAQPPPPPPP 306 Score = 32.0 bits (71), Expect = 4.2 Identities = 24/77 (31%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 73 PPRPDFVPFPPPMPPSAQGPLPPCP------IRPP-FPNHQMRHPFPVPPCFPPM--PPP 123 P P + P+ P P A G P P +PP P+ P + P PPP Sbjct: 982 PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPP 1041 Query: 124 MPCPNNPPVPGAPPGQG 140 P P PP P + P G Sbjct: 1042 PPPPPPPPAPASEPKGG 1058 Score = 32.0 bits (71), Expect = 4.2 Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 14/69 (20%) Query: 94 PPCPIRPPFPNHQMRHPFPV-----PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPP 148 PP P+R + Q ++P PP P PPP P PP Q P Sbjct: 1670 PPVPVRR---SGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQ------TPE 1720 Query: 149 PSMPHPPPP 157 +MP PP P Sbjct: 1721 TAMPEPPAP 1729 Score = 31.6 bits (70), Expect = 5.5 Identities = 33/114 (28%), Positives = 42/114 (36%), Gaps = 9/114 (7%) Query: 38 NLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFL--PPRPDFVPFPPPMPPSAQGPLPP 95 +L L+ P PP APS + S S L P D P PPP PP P+ P Sbjct: 789 DLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM-P 847 Query: 96 CPIRPPFPNHQMRHPFPVPPCFP--PMPPPMPCPN----NPPVPGAPPGQGTFP 143 + +H + P P P + PP P+P AP G P Sbjct: 848 LQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 71.6 bits (174), Expect = 5e-12 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 10/93 (10%) Query: 72 LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM-----PC 126 LPP P +P PPP+P S G L P P PP P P PP PP+PPP P Sbjct: 645 LPPPPASIPPPPPLP-SGLGSLSPAPPMPPVSAGPPLPPPPPPP--PPLPPPSSAGPPPP 701 Query: 127 PNNPPVPG--APPGQGTFPFMMPPPSMPHPPPP 157 P PP+P APP G P PPP + PPPP Sbjct: 702 PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPP 734 Score = 58.9 bits (141), Expect = 3e-08 Identities = 45/120 (37%), Positives = 49/120 (40%), Gaps = 16/120 (13%) Query: 47 PPVQYQYEPPSAPSTTFSNSPAPNFLP-----PRPDFVPFPPPMPPSAQGPLPPCPIRPP 101 PP PP PS S SPAP P P P P PPP+PP + PP P PP Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPP 706 Query: 102 FPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMP 161 PN P PP P PPP P PP APP F + S P P + P Sbjct: 707 LPNS------PAPPN-PGGPPPAP----PPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEP 755 Score = 40.8 bits (94), Expect = 0.009 Identities = 34/104 (32%), Positives = 37/104 (35%), Gaps = 25/104 (24%) Query: 44 PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFP 103 P PPV P P P + PP P PPP+P S P PP P PP Sbjct: 669 PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP---PPPLPNS---PAPPNPGGPP-- 720 Query: 104 NHQMRHPFPVPPCFPPMPPP----------MPCPNNPPV-PGAP 136 P P PP P PPP CP P + P P Sbjct: 721 ------PAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCP 758 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 71.6 bits (174), Expect = 5e-12 Identities = 49/123 (39%), Positives = 61/123 (49%), Gaps = 21/123 (17%) Query: 54 EPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPV 113 E PSAP T+ ++ P P + P V P + P+ PLPP P PP P P P Sbjct: 645 EMPSAPITS-ADCPKPMVVTPGAAAVAAPSVLAPTL--PLPPPPGFPPLPP-----PPPP 696 Query: 114 PPCFP--PMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHP---PPPPVMPQQVNYQY 168 PP P PMPPP+P P PP P P +PPP +P P PPPP++P + Sbjct: 697 PPPQPGFPMPPPLPPPPPPPPPAHP------AVTVPPPPLPAPPGVPPPPILPPLP--PF 748 Query: 169 PPG 171 PPG Sbjct: 749 PPG 751 Score = 63.5 bits (153), Expect = 1e-09 Identities = 63/195 (32%), Positives = 76/195 (38%), Gaps = 46/195 (23%) Query: 56 PSAPSTTFSNSPAPNF-LPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVP 114 P A + + AP LPP P F P PPP PP PP P M P P P Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP-----------PPQPGFPMPPPLPPP 712 Query: 115 PCFPPMPPPMPCPNNPPVP-GAPPGQGTFPFMMPPPSMPHPP--PPPVMP-QQVNYQYPP 170 P PP PP P PP P APPG + PPP +P P PP + P QV+ + Sbjct: 713 P--PPPPPAHPAVTVPPPPLPAPPG------VPPPPILPPLPPFPPGLFPVMQVDMSHVL 764 Query: 171 GYSHHNFPPPSFNSFQNN-----------------PSSFLPSANNSSSPHFRHLPPYPLP 213 G P SFQ P +A S+ F +LPPY P Sbjct: 765 GGQWGGMP----MSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGP 820 Query: 214 KAPSERRSPERLKHY 228 + S P R +H+ Sbjct: 821 FSLS-NSGPGRGQHW 834 Score = 60.8 bits (146), Expect = 8e-09 Identities = 124/528 (23%), Positives = 178/528 (33%), Gaps = 78/528 (14%) Query: 27 ARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMP 86 A +APS L L P P PP P F P P LPP P P PPP Sbjct: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGF---PMPPPLPPPP---PPPPPAH 720 Query: 87 PSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPP---PMPCPNNPPVPGAPPGQGTFP 143 P+ P PP P P P P P+ P PP PP P+ + V G G Sbjct: 721 PAVTVPPPPLPAPPGVP------PPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMS 774 Query: 144 FMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLP-SANNSSSP 202 F M + +M Q YPP + + F N P P S +NS Sbjct: 775 FQMQTQVLSR-----LMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPG 829 Query: 203 HFRHLPPYPL--PKAPSERRSPER---------------LKHYDDHRHRDHSHGRGE--R 243 +H PP P P P P + LK RD + E Sbjct: 830 RGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVA 889 Query: 244 HRSL----DRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRH----- 294 R+ D++ER S D DR + R S + E + Sbjct: 890 FRAFDEWWDKKERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGL 949 Query: 295 ----RDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEI 350 R R PS + K+ + + P + + E ++ D P E+ Sbjct: 950 GIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCEL 1009 Query: 351 VNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKP 410 R+ K R + S G++ S+ E++ ++ EEEEEE Sbjct: 1010 A-----KRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEE---- 1060 Query: 411 VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPK 470 ++ D + + T + + +D D EEE S K Sbjct: 1061 ---EDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTS-----------K 1106 Query: 471 TKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRL 518 + ESS SE ES +S+ SSS D E +V+A + ++ + + Sbjct: 1107 AEATSSSESSESSEFESSSESSPSSSEDEE--EVVAREEEEEEEEEEM 1152 Score = 57.0 bits (136), Expect = 1e-07 Identities = 55/210 (26%), Positives = 73/210 (34%), Gaps = 36/210 (17%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQYEPP----SAPSTTFSNSPAPNFLPPRPDFVPFPPP 84 P P + LL P+ P + + PP AP P P + P P P PPP Sbjct: 1226 PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP 1285 Query: 85 MPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPM-----PCPNNPPVPGAPPGQ 139 PP + P PP +H P P+ PP P + + VP P G+ Sbjct: 1286 RPP--RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGE 1343 Query: 140 -----GTFPFMMPPPSMPHPPPPPVMPQQVNYQYP---PGYSHHNFPPPSFNSFQNNPSS 191 G+ + P +P P + YP P S P F S Sbjct: 1344 PPLSGGSSGLSLSSPQVPGSP----------FSYPAPSPSLSSGGLPRTPGRDF-----S 1388 Query: 192 FLPSANNSSSPHFRHLPPYPLPKAPSERRS 221 F P+ + S P LP PLP + RS Sbjct: 1389 FTPTFSEPSGPLL--LPVCPLPTGRRDERS 1416 Score = 42.7 bits (99), Expect = 0.002 Identities = 44/183 (24%), Positives = 63/183 (34%), Gaps = 40/183 (21%) Query: 11 SFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPN 70 +F P G G S P F+ Q Q + + PP A +T PAP Sbjct: 345 AFRGSSDLPFGAVGGTGGSSGPPFKAQ-------PQDSATFAHTPPPAQAT-----PAPG 392 Query: 71 FLPPRPDFVPFPPPM---PPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCP 127 F + F P+ P+ PP + P R P P PP+PP P Sbjct: 393 F---KSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAP-----PPLPPAEPLA 444 Query: 128 NNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQN 187 P G PPG PPPP ++ + G+S P + ++ Sbjct: 445 KEKP--GTPPG---------------PPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLES 487 Query: 188 NPS 190 +P+ Sbjct: 488 SPA 490 Score = 42.7 bits (99), Expect = 0.002 Identities = 50/173 (28%), Positives = 63/173 (36%), Gaps = 36/173 (20%) Query: 18 CPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPR-- 75 CP G R S P P L P P+ P + P+ + + AP LPP Sbjct: 1405 CPLPTGRRDER-SGPLASPVLLETGLPLPLPLPLPL-PLALPAVLRAQARAPTPLPPLLP 1462 Query: 76 PDFVPFPPPM----------PPSA---QGPLPPCPIRPPFPNHQMRHPFPVP-----PCF 117 PPPM PPS GPL +RPP R +P P F Sbjct: 1463 APLASCPPPMKRKPGRPRRSPPSMLSLDGPL----VRPPAGAALGRELLLLPGQPQTPVF 1518 Query: 118 PPMPPPMPCP---NNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQ 167 P P N +P PP +PP P PPPPPV P ++ ++ Sbjct: 1519 PSTHDPRTVTLDFRNAGIPAPPPP-------LPPQPPPPPPPPPVEPTKLPFK 1564 Score = 39.7 bits (91), Expect = 0.020 Identities = 56/245 (22%), Positives = 71/245 (28%), Gaps = 75/245 (30%) Query: 41 LLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRP 100 LL Q+ + + EP S SP + PF P +GP PP RP Sbjct: 506 LLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSS-RP 564 Query: 101 PFPNHQMRHPFPVPPC---------FPPMPPPMPCPNNP--------------------- 130 + P P+P P PPP P P +P Sbjct: 565 SSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPT 624 Query: 131 --------------------PVPGAP-------------PGQGTF--PFMMPP------- 148 +P AP PG P ++ P Sbjct: 625 SEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684 Query: 149 PSMPH-PPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANN-SSSPHFRH 206 P P PPPPP P Q + PP PPP + P LP+ P Sbjct: 685 PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP 744 Query: 207 LPPYP 211 LPP+P Sbjct: 745 LPPFP 749 Score = 37.7 bits (86), Expect = 0.076 Identities = 34/124 (27%), Positives = 42/124 (33%), Gaps = 22/124 (17%) Query: 25 HGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTT----------FSNSPAPNFLPP 74 H P+ + P P Q PV + PP P+ T F +PAP LPP Sbjct: 380 HTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPP 439 Query: 75 RPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPG 134 P PP GP PP + M P F P P P P + Sbjct: 440 AEPLAKEKPGTPP---GPPPP-------DTNSME--LGGRPTFGWSPEPCDSPGTPTLES 487 Query: 135 APPG 138 +P G Sbjct: 488 SPAG 491 Score = 35.4 bits (80), Expect = 0.38 Identities = 38/130 (29%), Positives = 44/130 (33%), Gaps = 32/130 (24%) Query: 28 RPSAPSFRPQNLRLLHPQ-QPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMP 86 RP A + + L LL Q Q PV P + F N+ P PP P P PPP P Sbjct: 1495 RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPP 1554 Query: 87 PSAQGPLP--------PCPIRPPFPN----------------------HQMRHPFPVPPC 116 P LP P PP P + RH VPP Sbjct: 1555 PVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPA 1614 Query: 117 -FPPMPPPMP 125 P + PP P Sbjct: 1615 GSPELSPPQP 1624 Score = 33.1 bits (74), Expect = 1.9 Identities = 43/185 (23%), Positives = 58/185 (31%), Gaps = 58/185 (31%) Query: 28 RPSAPSFRPQNLRLLHPQQPPVQY-QYEPPSAPST--TFSNSPAPNFLPPRPDFVP---- 80 RP +P P+ HP PP + PP P + + S + +P P P Sbjct: 1289 RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSG 1348 Query: 81 ------------------FPPPMPPSAQGPLPPCPIR-----PPFPNHQMRHPFPVPPC- 116 +P P P + G LP P R P F + P +P C Sbjct: 1349 GSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTF--SEPSGPLLLPVCP 1406 Query: 117 FP---------------------PMPPPMPCPNNPPVPGAPPGQGTFPFMMPP----PSM 151 P P+P P+P P +P Q P +PP P Sbjct: 1407 LPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLA 1466 Query: 152 PHPPP 156 PPP Sbjct: 1467 SCPPP 1471 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 71.2 bits (173), Expect = 6e-12 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 17/111 (15%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCP------IRPPFPNHQMR 108 PP P P+P+ LP +P PPP+P SA+ P PP P I PP P Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTA-IPPPPPLPGSARIPPPPPPLPGSAGIPPPPP----- 696 Query: 109 HPFPVPPCFPPMPPPMPC-PNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPP 158 P P PP PPP+P P PP P P G G P PPP M PPPPP Sbjct: 697 -PLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGMGMPPPPP 743 Score = 59.7 bits (143), Expect = 2e-08 Identities = 58/180 (32%), Positives = 70/180 (38%), Gaps = 46/180 (25%) Query: 64 SNSPAPNFLPPR-PDFVPFPP--PMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM 120 S S A +PP P P PP P+P + +PP PP P P P PP PP Sbjct: 555 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPP----PPAPGDSTTPPPPPPP--PPP 608 Query: 121 PPPMP---CPNNPP-VPGA------PPGQGTFPFMMPPP-----SMPHP---------PP 156 PPP+P C ++PP +PG PP G PPP +P P PP Sbjct: 609 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP 668 Query: 157 PPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAP 216 PP +P + PP PPP P P + P PP PLP P Sbjct: 669 PPPLPGSA--RIPP-------PPPPLPGSAGIPPPPPPLPGEAGMPP----PPPPLPGGP 715 Score = 59.3 bits (142), Expect = 2e-08 Identities = 55/180 (30%), Positives = 63/180 (35%), Gaps = 40/180 (22%) Query: 29 PSAPSFRPQNLRLLHPQQPPVQYQ----YEPPSAPSTTFSNSPAPNFLPPRPDFVPFP-- 82 PS PS P P PP+ PP AP + + P P PP P P P Sbjct: 565 PSVPSRAPV------PPAPPLPGDSGTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGG 615 Query: 83 ----------------PPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMP- 125 PP P S +PP P P P PP PPP+P Sbjct: 616 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP-PPPLPG 674 Query: 126 CPNNPPVPGAPPGQGTFPFMMPPPSMP----HPPPPPVMPQQVNYQYPPGY-SHHNFPPP 180 PP P PG P PPP +P PPPPP +P PP + PPP Sbjct: 675 SARIPPPPPPLPGSAGIP--PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 732 Score = 58.9 bits (141), Expect = 3e-08 Identities = 42/136 (30%), Positives = 50/136 (36%), Gaps = 2/136 (1%) Query: 19 PRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDF 78 P G P P P+ + + P P PP + P P LP Sbjct: 633 PPPLSGDATIPPPPPL-PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 691 Query: 79 VPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPG 138 P PPP+P A P PP P+ P P PFP P PP PP M P PP P Sbjct: 692 PPPPPPLPGEAGMPPPPPPL-PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPA 750 Query: 139 QGTFPFMMPPPSMPHP 154 PF + P + P Sbjct: 751 APVLPFGLTPKKLYKP 766 Score = 56.2 bits (134), Expect = 2e-07 Identities = 54/185 (29%), Positives = 61/185 (32%), Gaps = 44/185 (23%) Query: 55 PPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPV- 113 PPS PS +P P P D PP P PP P PP P + + Sbjct: 564 PPSVPS----RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS 619 Query: 114 -PPCFP-----------------PMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPH-- 153 PP P P PPP+P P P + PG P PPP +P Sbjct: 620 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP---PPPPLPGSA 676 Query: 154 --PPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211 PPPPP +P PP PPP P P P PP P Sbjct: 677 RIPPPPPPLPGSAG--IPP-------PPPPLPGEAGMPPPPPPLPGGPGIP-----PPPP 722 Query: 212 LPKAP 216 P P Sbjct: 723 FPGGP 727 Score = 46.2 bits (108), Expect = 2e-04 Identities = 44/125 (35%), Positives = 51/125 (40%), Gaps = 23/125 (18%) Query: 113 VPPCFP---PMPPPMPCPNN-----PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQV 164 VPP P P+PP P P + PP P PG T P PPP P PPPP +P V Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPA--PGDSTTP--PPPPPPP--PPPPPLPGGV 616 Query: 165 NYQYP---PGYSHHNFPPPSFNSFQNNPSSFLPSA----NNSSSPHFRHLPPYPLPKAPS 217 P PG + + PPP P LP + SS P +P P P P Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP--PPPPLPG 674 Query: 218 ERRSP 222 R P Sbjct: 675 SARIP 679 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,391,490 Number of Sequences: 37866 Number of extensions: 4286909 Number of successful extensions: 63124 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 629 Number of HSP's successfully gapped in prelim test: 1520 Number of HSP's that attempted gapping in prelim test: 24208 Number of HSP's gapped (non-prelim): 16778 length of query: 1374 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1259 effective length of database: 13,892,928 effective search space: 17491196352 effective search space used: 17491196352 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.