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Search of human proteins with 150417973
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150417973 supervillin isoform 2 [Homo sapiens]
(2214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150417973 supervillin isoform 2 [Homo sapiens] 4430 0.0
gi|150417971 supervillin isoform 1 [Homo sapiens] 3020 0.0
gi|17572824 advillin [Homo sapiens] 182 4e-45
gi|194394237 villin 1 [Homo sapiens] 177 1e-43
gi|94721268 villin-like protein [Homo sapiens] 162 3e-39
gi|4504165 gelsolin isoform a precursor [Homo sapiens] 139 4e-32
gi|38044288 gelsolin isoform b [Homo sapiens] 139 4e-32
gi|189083782 gelsolin isoform c [Homo sapiens] 139 4e-32
gi|189083780 gelsolin isoform c [Homo sapiens] 139 4e-32
gi|189083778 gelsolin isoform b [Homo sapiens] 139 4e-32
gi|189083776 gelsolin isoform b [Homo sapiens] 139 4e-32
gi|189083774 gelsolin isoform b [Homo sapiens] 139 4e-32
gi|189083772 gelsolin isoform b [Homo sapiens] 139 4e-32
gi|162951877 scinderin isoform 1 [Homo sapiens] 135 6e-31
gi|4503743 flightless I homolog [Homo sapiens] 107 2e-22
gi|14916473 scinderin isoform 2 [Homo sapiens] 106 2e-22
gi|63252913 gelsolin-like capping protein [Homo sapiens] 62 8e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 60 2e-08
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 59 5e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 46 4e-04
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 46 5e-04
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 45 6e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 0.001
gi|50083281 KIAA1853 protein [Homo sapiens] 44 0.001
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 44 0.002
gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 44 0.002
gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Ho... 44 0.002
gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 44 0.002
gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 44 0.002
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 4430 bits (11489), Expect = 0.0
Identities = 2214/2214 (100%), Positives = 2214/2214 (100%)
Query: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE
Sbjct: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
Query: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY
Sbjct: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
Query: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG
Sbjct: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
Query: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT
Sbjct: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
Query: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINW 300
EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINW
Sbjct: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINW 300
Query: 301 PSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAAGST 360
PSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAAGST
Sbjct: 301 PSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAAGST 360
Query: 361 RQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVL 420
RQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVL
Sbjct: 361 RQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVL 420
Query: 421 HVCESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKP 480
HVCESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKP
Sbjct: 421 HVCESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKP 480
Query: 481 AVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKK 540
AVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKK
Sbjct: 481 AVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKK 540
Query: 541 RKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSA 600
RKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSA
Sbjct: 541 RKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSA 600
Query: 601 FLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQPI 660
FLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQPI
Sbjct: 601 FLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQPI 660
Query: 661 TSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRN 720
TSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRN
Sbjct: 661 TSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRN 720
Query: 721 TAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPA 780
TAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPA
Sbjct: 721 TAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPA 780
Query: 781 RLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRID 840
RLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRID
Sbjct: 781 RLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRID 840
Query: 841 TRQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPL 900
TRQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPL
Sbjct: 841 TRQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPL 900
Query: 901 DHNASATDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRD 960
DHNASATDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRD
Sbjct: 901 DHNASATDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRD 960
Query: 961 SGMEKYGSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSM 1020
SGMEKYGSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSM
Sbjct: 961 SGMEKYGSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSM 1020
Query: 1021 AKMNAQGNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAP 1080
AKMNAQGNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAP
Sbjct: 1021 AKMNAQGNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAP 1080
Query: 1081 VSWKPQDSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEE 1140
VSWKPQDSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEE
Sbjct: 1081 VSWKPQDSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEE 1140
Query: 1141 DWRNRLSRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKT 1200
DWRNRLSRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKT
Sbjct: 1141 DWRNRLSRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKT 1200
Query: 1201 RGRGAANDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQ 1260
RGRGAANDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQ
Sbjct: 1201 RGRGAANDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQ 1260
Query: 1261 LESDLKLDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMP 1320
LESDLKLDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMP
Sbjct: 1261 LESDLKLDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMP 1320
Query: 1321 RSPVEMDEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTE 1380
RSPVEMDEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTE
Sbjct: 1321 RSPVEMDEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTE 1380
Query: 1381 QRLNVAFMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPY 1440
QRLNVAFMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPY
Sbjct: 1381 QRLNVAFMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPY 1440
Query: 1441 KRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELA 1500
KRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELA
Sbjct: 1441 KRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELA 1500
Query: 1501 TLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAII 1560
TLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAII
Sbjct: 1501 TLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAII 1560
Query: 1561 ETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAF 1620
ETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAF
Sbjct: 1561 ETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAF 1620
Query: 1621 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1680
QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL
Sbjct: 1621 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1680
Query: 1681 DWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVE 1740
DWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVE
Sbjct: 1681 DWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVE 1740
Query: 1741 GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGE 1800
GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGE
Sbjct: 1741 GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGE 1800
Query: 1801 HSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQ 1860
HSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQ
Sbjct: 1801 HSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQ 1860
Query: 1861 GGMVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKA 1920
GGMVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKA
Sbjct: 1861 GGMVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKA 1920
Query: 1921 LIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG 1980
LIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG
Sbjct: 1921 LIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG 1980
Query: 1981 RRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYS 2040
RRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYS
Sbjct: 1981 RRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYS 2040
Query: 2041 APQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
APQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA
Sbjct: 2041 APQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
Query: 2101 PKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLA 2160
PKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLA
Sbjct: 2101 PKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLA 2160
Query: 2161 DLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
DLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
Sbjct: 2161 DLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
>gi|150417971 supervillin isoform 1 [Homo sapiens]
Length = 1788
Score = 3020 bits (7830), Expect = 0.0
Identities = 1513/1545 (97%), Positives = 1513/1545 (97%), Gaps = 32/1545 (2%)
Query: 670 RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR 729
RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR
Sbjct: 276 RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR 335
Query: 730 LQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPARLQASAHQK 789
LQDRSLTQPITTEEVVIAAT LQASAHQK
Sbjct: 336 LQDRSLTQPITTEEVVIAAT--------------------------------LQASAHQK 363
Query: 790 ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR 849
ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR
Sbjct: 364 ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR 423
Query: 850 YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY 909
YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY
Sbjct: 424 YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY 483
Query: 910 KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF 969
KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF
Sbjct: 484 KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF 543
Query: 970 EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL 1029
EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL
Sbjct: 544 EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL 603
Query: 1030 DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS 1089
DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS
Sbjct: 604 DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS 663
Query: 1090 EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR 1149
EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR
Sbjct: 664 EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR 723
Query: 1150 QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS 1209
QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS
Sbjct: 724 QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS 783
Query: 1210 TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR 1269
TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR
Sbjct: 784 TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR 843
Query: 1270 LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED 1329
LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED
Sbjct: 844 LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED 903
Query: 1330 FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME 1389
FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME
Sbjct: 904 FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME 963
Query: 1390 SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK
Sbjct: 964 SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
Query: 1450 GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL 1509
GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL
Sbjct: 1024 GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL 1083
Query: 1510 GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM 1569
GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM
Sbjct: 1084 GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM 1143
Query: 1570 DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG 1629
DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG
Sbjct: 1144 DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG 1203
Query: 1630 TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN 1689
TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN
Sbjct: 1204 TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN 1263
Query: 1690 EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI 1749
EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI
Sbjct: 1264 EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI 1323
Query: 1750 TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE 1809
TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE
Sbjct: 1324 TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE 1383
Query: 1810 KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR 1869
KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR
Sbjct: 1384 KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR 1443
Query: 1870 REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK 1929
REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK
Sbjct: 1444 REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK 1503
Query: 1930 AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC 1989
AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC
Sbjct: 1504 AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC 1563
Query: 1990 MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV 2049
MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV
Sbjct: 1564 MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV 1623
Query: 2050 DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG 2109
DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG
Sbjct: 1624 DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG 1683
Query: 2110 LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE 2169
LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE
Sbjct: 1684 LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE 1743
Query: 2170 GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
Sbjct: 1744 GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
Score = 548 bits (1411), Expect = e-155
Identities = 280/326 (85%), Positives = 294/326 (90%)
Query: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE
Sbjct: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
Query: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY
Sbjct: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
Query: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG
Sbjct: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
Query: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT
Sbjct: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
Query: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINW 300
EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARP + + + D + ++
Sbjct: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPRCTSHSETPTVDDEEKVDERAKLSV 300
Query: 301 PSRVKVREKLVKEESARNSPELASES 326
++ + ++ K +N P+ S +
Sbjct: 301 AAKRLLFREMEKSFDEQNVPKRRSRN 326
Score = 38.1 bits (87), Expect = 0.097
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 15/124 (12%)
Query: 631 ERERGSRKPRRYFSPGESRKTSERFRTQPITSAER--KESDRCTSHSETPTVDDEEKVDE 688
E+ R+ R R+ +R TQPIT+ E + + ++H + D + E
Sbjct: 316 EQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATLQASAHQKALAKDQTNEGKE 375
Query: 689 RAK--------LSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPIT 740
A+ LS+A K LF ++ Q V K S ++ R RR+ R TQP+T
Sbjct: 376 LAEQGEPDSSTLSLAEKLALFNKLS-----QPVSKAISTRNRIDTRQRRMNARYQTQPVT 430
Query: 741 TEEV 744
EV
Sbjct: 431 LGEV 434
>gi|17572824 advillin [Homo sapiens]
Length = 819
Score = 182 bits (461), Expect = 4e-45
Identities = 208/801 (25%), Positives = 328/801 (40%), Gaps = 148/801 (18%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
LL +KG+R+++ VE + N GD FLL W G +N E+ KA LA I+
Sbjct: 136 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 195
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-EDELYEAAIIETN 1563
RE G RA I IE A+ + K+L +S P DE+ + T
Sbjct: 196 D-RERGGRAE-IGVIE---GDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTI 250
Query: 1564 CIYRLMDD--KLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAF 1620
+Y + D +L + + + LL + + D G+++YVW GK T A+++ A
Sbjct: 251 MLYHISDSAGQLAVTEVATRPLVQ-DLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
Query: 1621 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1680
A + ++ ++ G E+ +FK+ F
Sbjct: 310 SKALGFIKMKSYPSSTNVETVNDGA-------------------------ESAMFKQLFQ 344
Query: 1681 DWTELKRS----NEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
W+ ++ + G++A+ +D +DVT + + P+ A + V+ G G
Sbjct: 345 KWSVKDQTMGLGKTFSIGKIAKVFQDK------FDVTLLHTKPEVAAQERM--VDDGNG- 395
Query: 1737 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1796
V+VW I + + Q G F+ GD Y+V + + V+
Sbjct: 396 ----------------KVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN------ 433
Query: 1797 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEE---RGAQVQVLQGKEPP 1853
GK + + WQGRH++ E SA VE+D + QV+V G EP
Sbjct: 434 ----------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPR 483
Query: 1854 CFLQCFQGGMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1912
F+ F+G +V+ G + RL+ + G +EV SSL S
Sbjct: 484 HFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND-- 541
Query: 1913 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1972
V L +A YLW+G + + + + A+ + + S+ T+ E G EP
Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD----------GSENTVAE---GQEP 588
Query: 1973 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 2032
FWD LG + A D LQ + RLF S+ +G F TE
Sbjct: 589 AEFWDLLGGKTPYANDKRLQQE-ILDVQSRLFECSNKTGQFVVTEIT------------D 635
Query: 2033 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 2092
F Q+DL + L+D +V+LW G A A++++SA+ T QY
Sbjct: 636 FTQDDLNPTD---VMLLDTWDQVFLWIG---------AEAN---ATEKESALATAQQYLH 680
Query: 2093 GK-NLKKPAPKSYLIHAGLEPLTFTNMFPSW---------------EHREDIAEITEMDT 2136
+ + P +I G EP FT F +W E D A I +
Sbjct: 681 THPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITA 740
Query: 2137 EVSNQITLVEDVLAKLCKTIYPLADLLA---RPLPEGVDPLKLEIYLTDEDFEFALDMTR 2193
++ N + ++ YP+A LL + LPE V+P K E YL+++DF +TR
Sbjct: 741 DMKNATLSLNSNDSE--PKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITR 798
Query: 2194 DEYNALPAWKQVNLKKAKGLF 2214
++ ALP WKQ+ +KK KGLF
Sbjct: 799 GQFAALPGWKQLQMKKEKGLF 819
Score = 61.2 bits (147), Expect = 1e-08
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 23/192 (11%)
Query: 1436 SAVPYKRLMLLQIKGRRHVQTRLVEPRA--SALNSGDCFLLLSPHCCFLWVGEFANVIEK 1493
+A P + L QI G T+ VE A S+LNS D FLL + +LW G+ ++ E+
Sbjct: 505 NAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDER 564
Query: 1494 AKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-ED 1552
A A ELA+L+ E T+ EG +FW LLGG+T Y A D + +
Sbjct: 565 AMAKELASLLCDGSE--------NTVAEG-----QEPAEFWDLLGGKTPY--ANDKRLQQ 609
Query: 1553 ELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVT 1612
E+ + C + + D+ L P +V++ D +V++W G E
Sbjct: 610 EILDVQSRLFECSNKTGQFVVTEITDF-----TQDDLNPTDVMLLDTWDQVFLWIGAEAN 664
Query: 1613 LAQRKIAFQLAK 1624
+++ A A+
Sbjct: 665 ATEKESALATAQ 676
Score = 58.9 bits (141), Expect = 5e-08
Identities = 84/383 (21%), Positives = 157/383 (40%), Gaps = 62/383 (16%)
Query: 1756 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1815
VW I + + + +P + G F+EGD YV+ +ST R A F
Sbjct: 18 VWRIEKMELALVPVSAHGNFYEGDCYVI-----LSTR-----------RVASLLSQDIHF 61
Query: 1816 WQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSG---- 1868
W G+ S+ E+ +A+ T +LD+ G Q + +Q E F F+ G++ G
Sbjct: 62 WIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVAS 121
Query: 1869 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGC 1928
+ E N RL V+G+ + +E++ +R + +L++ K +I W+G
Sbjct: 122 GMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSF---NRGDVFLLDLGKVIIQ-WNGP 177
Query: 1929 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDALGRRD--- 1983
++ + + A I+++ E G + V + + S L D LGRR
Sbjct: 178 ESNSGERLKAMLLAKDIRDR---ERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 234
Query: 1984 RKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQ 2043
D ++ L+ +S S+G A TE V++ P +Q+ L
Sbjct: 235 PTVPDEIIDQKQKSTI--MLYHISDSAGQLAVTE----------VATRPLVQDLLNH--D 280
Query: 2044 PALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKS 2103
L + ++Y+W+G G+ + +++++AM L + K K+ +
Sbjct: 281 DCYILDQSGTKIYVWKG--------KGATK----AEKQAAMSKALGFIKMKSYPS-STNV 327
Query: 2104 YLIHAGLEPLTFTNMFPSWEHRE 2126
++ G E F +F W ++
Sbjct: 328 ETVNDGAESAMFKQLFQKWSVKD 350
>gi|194394237 villin 1 [Homo sapiens]
Length = 827
Score = 177 bits (448), Expect = 1e-43
Identities = 199/799 (24%), Positives = 320/799 (40%), Gaps = 139/799 (17%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
LL +KG+R+V VE + N GD FLL W G + +E+ + LA I+
Sbjct: 139 LLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIR 198
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
+ G TY+ ++ + + + G+ A P D + E A+
Sbjct: 199 DQERGG--RTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVP--DTVVEPALKAALK 254
Query: 1565 IYRLMDDK--LVPDDDYWGKIPKCSLLQPKEVLVFDFGS-EVYVWHGKEVTLAQRKIAFQ 1621
+Y + D + LV + + + LL ++ + D G ++YVW GK+ ++K A
Sbjct: 255 LYHVSDSEGNLVVREVATRPLTQ-DLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMS 313
Query: 1622 LAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLD 1681
A +N + + P + Q + E+ +F++ F
Sbjct: 314 HA--------------LNFIKAKQYPPSTQVEVQN-----------DGAESAVFQQLFQK 348
Query: 1682 WTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEG 1741
WT R++ G+ + + +D T M PQ A
Sbjct: 349 WTASNRTS--GLGKTHTVGSVAKVEQVKFDATSMHVKPQVAA------------------ 388
Query: 1742 HDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEH 1801
++ + S V VW I + + + +G F+ GD Y++ + +++ GE
Sbjct: 389 -QQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLI---------GE- 437
Query: 1802 SVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGA---QVQVLQGKEPPCFLQC 1858
K+ + + WQG ++ E SA V LD++ Q++V GKEPP +
Sbjct: 438 ------KQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSI 491
Query: 1859 FQGGMVVHSGRREEEEE-NVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNV 1917
F+G MVV+ G RL+ V+G EV + L S V+
Sbjct: 492 FKGRMVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKT- 550
Query: 1918 NKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWD 1977
++ YLW G +E+ + A+ I + +V + EG EP FW
Sbjct: 551 -QSCCYLWCGKGCSGDEREMAKMVADTISR---------TEKQVVV----EGQEPANFWM 596
Query: 1978 ALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQED 2037
ALG + A LQ+ + PRLF S+ +G F ATE F Q+D
Sbjct: 597 ALGGKAPYANTKRLQEE-NLVITPRLFECSNKTGRFLATEIP------------DFNQDD 643
Query: 2038 LYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGK-NL 2096
L + +FL+D +V+ W G E ++K+A T +Y K +
Sbjct: 644 L---EEDDVFLLDVWDQVFFWIGKHANEE------------EKKAAATTAQEYLKTHPSG 688
Query: 2097 KKPAPKSYLIHAGLEPLTFTNMFPSWE------------------HREDIAEITEMDTEV 2138
+ P ++ G EP TFT F +W+ + D ++IT T
Sbjct: 689 RDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQITAEVTSP 748
Query: 2139 SNQITLVEDVLAKLCKTIYPLADLLARP---LPEGVDPLKLEIYLTDEDFEFALDMTRDE 2195
+ L+ I+PL L+ +P LPEGVDP + E +L+ EDF A MT
Sbjct: 749 KVDVFNANSNLSSGPLPIFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAA 808
Query: 2196 YNALPAWKQVNLKKAKGLF 2214
++ALP WKQ NLKK KGLF
Sbjct: 809 FSALPRWKQQNLKKEKGLF 827
Score = 73.2 bits (178), Expect = 3e-12
Identities = 90/384 (23%), Positives = 154/384 (40%), Gaps = 58/384 (15%)
Query: 1749 ITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGK 1808
IT+ + +W I +P + G F +GD Y++ + S H
Sbjct: 14 ITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYII---LAIHKTASSLSYDIH------- 63
Query: 1809 EKCVYFFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVV 1865
+W G+ S++ E+G +A+ T ++D+ R Q + +QG E F F+ G+V+
Sbjct: 64 ------YWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVI 117
Query: 1866 HSG----RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKAL 1921
G + E N RL V+G+ V +E++ +R + +L++ K L
Sbjct: 118 RKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSF---NRGDVFLLDLGK-L 173
Query: 1922 IYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDAL 1979
I W+G ++ + G T A +I++Q E G + V E + S L L
Sbjct: 174 IIQWNGPESTRMERLRGMTLAKEIRDQ---ERGGRTYVGVVDGENELASPKLMEVMNHVL 230
Query: 1980 G-RRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDL 2038
G RR+ KA + A +L+ +S S G+ E ++S ED
Sbjct: 231 GKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLS-----HEDC 285
Query: 2039 YSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKK 2098
Y Q L ++Y+W+G E ++K AM L + K K
Sbjct: 286 YILDQGGL-------KIYVWKGKKANE------------QEKKGAMSHALNFIKAKQY-P 325
Query: 2099 PAPKSYLIHAGLEPLTFTNMFPSW 2122
P+ + + + G E F +F W
Sbjct: 326 PSTQVEVQNDGAESAVFQQLFQKW 349
Score = 60.5 bits (145), Expect = 2e-08
Identities = 69/273 (25%), Positives = 109/273 (39%), Gaps = 52/273 (19%)
Query: 1429 TEQNSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFA 1488
T + +N P RL +Q G + + V RA+ LNS D F+L + CC+LW G+
Sbjct: 503 TSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGC 562
Query: 1489 NVIEKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD 1548
+ E+ A +A I T Q + EG +FW LGG+ Y +
Sbjct: 563 SGDEREMAKMVADTIS--------RTEKQVVVEG-----QEPANFWMALGGKAPYANTKR 609
Query: 1549 PKEDEL-YEAAIIE-TNCIYRLMDDKLVPD---DDYWGKIPKCSLLQPKEVLVFDFGSEV 1603
+E+ L + E +N R + + +PD DD L+ +V + D +V
Sbjct: 610 LQEENLVITPRLFECSNKTGRFLATE-IPDFNQDD----------LEEDDVFLLDVWDQV 658
Query: 1604 YVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIF 1663
+ W GK ++K A A+ +Y + DP E ++ ++G P
Sbjct: 659 FFWIGKHANEEEKKAAATTAQ-------EYLKTHPSGRDP-ETPIIVVKQGHEPP----- 705
Query: 1664 GRLTEHNETILFKEKFLDWTELKRSNEKNPGEL 1696
F FL W K SN K+ +L
Sbjct: 706 ----------TFTGWFLAWDPFKWSNTKSYEDL 728
>gi|94721268 villin-like protein [Homo sapiens]
Length = 856
Score = 162 bits (410), Expect = 3e-39
Identities = 206/842 (24%), Positives = 314/842 (37%), Gaps = 194/842 (23%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
LL IKGR+HV VE ++ N GD FLL W G ++ EKA+ L ++
Sbjct: 137 LLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALTYSLR 196
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKL----LGGQTSYQSAGDPKED-ELYEAAI 1559
+ G RA + G+ A D ++ LG + A P +D + A
Sbjct: 197 DRERGGGRA------QIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKAN 250
Query: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCS--LLQPKEVLVFDFGS-EVYVWHGKEVTLAQR 1616
+ +Y D +V + P + LLQ ++ + D G ++YVW G+ +L +R
Sbjct: 251 VRLYHVYEKGKDLVVLEL----ATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQER 306
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K AF A + +G P + + + E+ FK
Sbjct: 307 KAAFSRAVGFI-------------------------QAKGYPTYTNVEVVNDGAESAAFK 341
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F W+E +R N+K G D VK DV ++ + P+ A
Sbjct: 342 QLFRTWSEKRRRNQKLGGR------DKSIHVKL-DVGKLHTQPKLAA------------- 381
Query: 1737 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1796
R + S V+VW I + + + GQ G+ Y+V + +
Sbjct: 382 ------QLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTY--------- 426
Query: 1797 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGA---QVQVLQGKEPP 1853
+ G+ + + + WQG +T E ELD G Q V G EPP
Sbjct: 427 -------QRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPP 479
Query: 1854 CFLQCFQGGMVVHSGRREEEEENVQ-SEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1912
FL FQG +V+ R + S RL+ V+G +EV SSL S S
Sbjct: 480 HFLAIFQGQLVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNS--SD 537
Query: 1913 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1972
+ L V ++ YLW G +E+ R I S+ EG EP
Sbjct: 538 IFLLVTASVCYLWFGKGCNGDQREMARVVVTVI-------------SRKNEETVLEGQEP 584
Query: 1973 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 2032
FW+ALG R + L + +F PRLF SS G E +
Sbjct: 585 PHFWEALGGRAPYPSNKRLPEEVP-SFQPRLFECSSHMGCLVLAEVGF------------ 631
Query: 2033 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 2092
F QEDL + + L+D E++LW G AS+ K A+ +Y K
Sbjct: 632 FSQEDL---DKYDIMLLDTWQEIFLWLG--------------EAASEWKEAVAWGQEYLK 674
Query: 2093 GKNL-KKPAPKSYLIHAGLEPLTFTNMFPSWE---------HREDI-------AEITEMD 2135
+ PA L+ G EP TF F +W+ H+E + + I+E+
Sbjct: 675 THPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGSPAAASTISEIT 734
Query: 2136 TEVSN---------------------------QITLVEDVLAKLCKTIYPLADLLA---- 2164
EV+N + LV + +T ++ A
Sbjct: 735 AEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSSSVSSTSATING 794
Query: 2165 ------------RPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKG 2212
LPEGVDP + E YL+D DF+ +++E+ ++ W+Q KK G
Sbjct: 795 GLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMATWRQRQEKKQLG 854
Query: 2213 LF 2214
F
Sbjct: 855 FF 856
Score = 62.0 bits (149), Expect = 6e-09
Identities = 68/299 (22%), Positives = 123/299 (41%), Gaps = 58/299 (19%)
Query: 1348 HKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLN----VAFM----ESKRMKVEKMS 1399
H++ V PKR Q L A L YT QRL + ++ ++ ++E ++
Sbjct: 402 HRQPVDPKRHGQ--------LCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALN 453
Query: 1400 SNSNFSEVTLAGLASKEN-------------FSNVSLRSVNLTEQNSNNSAVPYKRLMLL 1446
SN+ +V G+ +E+ F + + + RL +
Sbjct: 454 SNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSASTTRLFQV 513
Query: 1447 QIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTK 1506
Q + +T V RAS+LNS D FLL++ C+LW G+ N ++ A + T+I K
Sbjct: 514 QGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRK 573
Query: 1507 RELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD-PKEDELYEAAIIETN-- 1563
E +T+ EG FW+ LGG+ Y S P+E ++ + E +
Sbjct: 574 NE--------ETVLEG-----QEPPHFWEALGGRAPYPSNKRLPEEVPSFQPRLFECSSH 620
Query: 1564 --CIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAF 1620
C+ L + +D L ++++ D E+++W G+ + + +A+
Sbjct: 621 MGCLV-LAEVGFFSQED----------LDKYDIMLLDTWQEIFLWLGEAASEWKEAVAW 668
>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
Length = 782
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 189 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 249 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 299
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 300 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 356 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 390
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 391 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 437
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 438 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 480
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 481 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 533 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 593 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 636
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 637 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 683
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 684 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 733
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 734 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 764
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 68 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 113
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 114 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 172
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 173 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 227
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 228 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 280
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 281 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 330
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 331 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 375
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 376 QVSVLPEGGETPL-FKQFFKNW 396
>gi|38044288 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083782 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 336 QVSVLPEGGETPL-FKQFFKNW 356
>gi|189083780 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 336 QVSVLPEGGETPL-FKQFFKNW 356
>gi|189083778 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083776 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083774 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083772 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 4e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|162951877 scinderin isoform 1 [Homo sapiens]
Length = 715
Score = 135 bits (339), Expect = 6e-31
Identities = 160/703 (22%), Positives = 293/703 (41%), Gaps = 154/703 (21%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
LL +KGRR V+ V + N GDCF++ + W G N E+ KA+++AT I+
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
G + + +EEG + K+LG + GD +D + + + +
Sbjct: 199 YNERKG--RSELIVVEEG-----SEPSELIKVLGEKPELPDGGD-DDDIIADISNRKMAK 250
Query: 1565 IYRLMDDK------LVPDDDYWGKIPKCSLLQPKEVLVFDFGS--EVYVWHGKEVTLAQR 1616
+Y + D +V +++ + ++L +E + D G+ +++VW GK+ +R
Sbjct: 251 LYMVSDASGSMRVTVVAEENPF----SMAMLLSEECFILDHGAAKQIFVWKGKDANPQER 306
Query: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
K A + A+ +N I L G ET +FK
Sbjct: 307 KAAMKTAEEFLQQMNYSKNTQIQVLPEG-------------------------GETPIFK 341
Query: 1677 EKFLDWTELKRSNEKN----PGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNV 1732
+ F DW + +S+ ++AQ K+ P +D +++ S PQ A
Sbjct: 342 QFFKDWRDKDQSDGFGKVYVTEKVAQIKQIP------FDASKLHSSPQMAA--------- 386
Query: 1733 GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTA 1792
+ S V++W + ++ + S G+F+ GD Y++ + +
Sbjct: 387 ----------QHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY----- 431
Query: 1793 VGSRQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQG 1849
+G+ + + WQG ++T E TSA +TV+LD G Q++V QG
Sbjct: 432 ----PRGQ-----------IIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQG 476
Query: 1850 KEPPCFLQCFQGG--MVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLR 1907
KEP L F+ ++ +G ++ + RL+ VR + ++EV +SL
Sbjct: 477 KEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLN 536
Query: 1908 SRTSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECD 1967
S + VL + + Y+W VG+ A+ + ++ A + + I
Sbjct: 537 S-NDVFVLKLPQNSGYIW-----------VGKGASQEEEKGAEYVASVLKCKTLRI---Q 581
Query: 1968 EGSEPLGFWDALGRRDRKAYDCM-LQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPS 2026
EG EP FW++LG +K Y L + + + PRL+ S+ +G F
Sbjct: 582 EGEEPEEFWNSLG--GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRF------------- 626
Query: 2027 VVSSMP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAM 2084
V+ +P F Q+DL + + L+D ++++W G N++ ++K ++
Sbjct: 627 VIEEIPGEFTQDDL---AEDDVMLLDAWEQIFIWIG--KDANEV----------EKKESL 671
Query: 2085 ETVLQYCK----GKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
++ Y + G++ + P +I G EP TFT F W+
Sbjct: 672 KSAKMYLETDPSGRDKRTPI---VIIKQGHEPPTFTGWFLGWD 711
Score = 64.7 bits (156), Expect = 1e-09
Identities = 91/387 (23%), Positives = 150/387 (38%), Gaps = 68/387 (17%)
Query: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
+ VW I + + +P+ + G F+ GDAY+V + TA SR H
Sbjct: 19 LQVWRIEKLELVPVPQSAHGDFYVGDAYLV-----LHTAKTSRGFTYH-----------L 62
Query: 1814 FFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSGRR 1870
FW G+ + E +A+ TV++D+ G Q + LQG E F+ F+GG+ +G
Sbjct: 63 HFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGV 122
Query: 1871 EEEEENVQSE----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLW 1925
+V + RL V+G V EV S ++ L IY W
Sbjct: 123 ASGLNHVLTNDLTAKRLLHVKGRRVVRAT--EVPLSWDSFNKGDCFIIDLGTE---IYQW 177
Query: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
G + R AN++ S + + +EGSEP LG +
Sbjct: 178 CGSSCNKYE----RLKANQVATGIRYNERKGRSELIVV---EEGSEPSELIKVLGEKPEL 230
Query: 1983 -DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSA 2041
D D ++ D + A +L+++S +SG R V PF L S
Sbjct: 231 PDGGDDDDIIADISNRKMA-KLYMVSDASGSM---------RVTVVAEENPFSMAMLLS- 279
Query: 2042 PQPALFLVDN--HHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKP 2099
F++D+ ++++W+G + +RK+AM+T ++ + N K
Sbjct: 280 --EECFILDHGAAKQIFVWKG------------KDANPQERKAAMKTAEEFLQQMNYSKN 325
Query: 2100 APKSYLIHAGLEPLTFTNMFPSWEHRE 2126
L G P+ F F W ++
Sbjct: 326 TQIQVLPEGGETPI-FKQFFKDWRDKD 351
>gi|4503743 flightless I homolog [Homo sapiens]
Length = 1269
Score = 107 bits (266), Expect = 2e-22
Identities = 172/745 (23%), Positives = 290/745 (38%), Gaps = 171/745 (22%)
Query: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
+ ++ G+++++ V + ++L+ FLL ++W G A + KA A I
Sbjct: 621 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKIN 680
Query: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE-----DELYEAAI 1559
G I + +G +FW+ LGG+ S P++ +LY+ +
Sbjct: 681 KNERKG--KAEITLLVQG-----QELPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGL 733
Query: 1560 ----IETNCI-YRL-MDDKLVPDDDYWGKIPKC-SLLQPKEVLVFDFGSEVYVWHGKEVT 1612
+E I Y+L ++ K P + ++ SLL + V + D S+V++W G++
Sbjct: 734 GLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSP 793
Query: 1613 LAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNET 1672
R A +L + L C L RP A R E E
Sbjct: 794 RLVRAAALKLGQEL-------------------CGML------HRPRHATVSRSLEGTEA 828
Query: 1673 ILFKEKFLDWTEL-----KRSNE---KNPG------ELAQHKEDPRTDVKAYDVTRMVSM 1718
+FK KF +W ++ R+ E ++PG A+ K+ + D+ A + R M
Sbjct: 829 QVFKAKFKNWDDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPM 888
Query: 1719 PQTTAGTILDGVNV---GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQF 1775
A +++ N G ++EG ++RLP++ G F
Sbjct: 889 SLAEAEQLMEEWNEDLDGMEGFVLEGKK--------------------FARLPEEEFGHF 928
Query: 1776 HEGDAYVVKWKFMVSTAVGSRQKGE-HSVRAAGKE-----------------KCVYFFWQ 1817
+ D YV ++ V +K E +A GKE +C+ +FWQ
Sbjct: 929 YTQDCYVFLCRYWVPVEYEEEEKKEDKEEKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQ 988
Query: 1818 GRHST---------VSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSG 1868
GR ++ +K +L +L+ V++ Q +E P FL F+ ++H G
Sbjct: 989 GREASNMGWLTFTFSLQKKFESLFPGKLE-----VVRMTQQQENPKFLSHFKRKFIIHRG 1043
Query: 1869 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVAC----HCSSLRSRTSMVVLNV------N 1918
+R+ + Q LY +R G+ L C SSL + +L V N
Sbjct: 1044 KRKAVQGAQQPS--LYQIR----TNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDN 1097
Query: 1919 KALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLG-FWD 1977
+ ++Y W G + ++ N + + S SK I +EG EP FW
Sbjct: 1098 QGIVYAWVGRASDPDEAKLAEDILNTMFDT--------SYSKQVI---NEGEEPENFFWV 1146
Query: 1978 ALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQED 2037
+G +K YD D + RLF S+ G FA TE F Q+D
Sbjct: 1147 GIGA--QKPYD----DDAEYMKHTRLFRCSNEKGYFAVTE-----------KCSDFCQDD 1189
Query: 2038 LYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLK 2097
L + L+DN EVY+W G + +I S + A + +Q+ + K +
Sbjct: 1190 L---ADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLK---------ACQVYIQHMRSKEHE 1237
Query: 2098 KPAPKSYLIHAGLEPLTFTNMFPSW 2122
+P + L+ G E FT F +W
Sbjct: 1238 RPR-RLRLVRKGNEQHAFTRCFHAW 1261
Score = 51.2 bits (121), Expect = 1e-05
Identities = 58/232 (25%), Positives = 92/232 (39%), Gaps = 34/232 (14%)
Query: 1756 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1815
+W I F + + G+F+E D Y+V F+ + G ++
Sbjct: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDS---------------GSLNWEIYY 547
Query: 1816 WQGRHSTVSEKGTSALMTVELDEERGAQVQVLQ---GKEPPCFLQCFQGGMVVHSGRREE 1872
W G +T+ +K SA+ V L GA+ + ++ G E FLQ F + G
Sbjct: 548 WIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTAS 607
Query: 1873 ---EEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKAL-IYLWHGC 1928
E+ R+Y V G+ ++ L V +SL R V +++ L IY+W G
Sbjct: 608 GFYTVEDTHYVTRMYRVYGKKNIK--LEPVPLKGTSLDPR---FVFLLDRGLDIYVWRGA 662
Query: 1929 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG 1980
+A + R A KI + K I +G E FW+ALG
Sbjct: 663 QATLSSTTKARLFAEKINKN-------ERKGKAEITLLVQGQELPEFWEALG 707
Score = 40.0 bits (92), Expect = 0.025
Identities = 59/258 (22%), Positives = 100/258 (38%), Gaps = 62/258 (24%)
Query: 1399 SSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVP-YKRLMLLQIKGRRHVQ-- 1455
+SN + T + E+ L V +T+Q N + +KR ++ R+ VQ
Sbjct: 992 ASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAVQGA 1051
Query: 1456 ----------------TRLVEPR--ASALNSGDCFLLLSPH-------CCFLWVGEFANV 1490
TR ++ +S LNS CF+L P + WVG A+
Sbjct: 1052 QQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGR-ASD 1110
Query: 1491 IEKAKASE--LATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD 1548
++AK +E L T+ T Q I EG FW +G Q Y
Sbjct: 1111 PDEAKLAEDILNTMFDTSYSK-------QVINEGEEPENF----FWVGIGAQKPYDD--- 1156
Query: 1549 PKEDELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSL-----LQPKEVLVFDFGSEV 1603
+A ++ ++R ++K Y+ KCS L ++++ D G EV
Sbjct: 1157 -------DAEYMKHTRLFRCSNEK-----GYFAVTEKCSDFCQDDLADDDIMLLDNGQEV 1204
Query: 1604 YVWHGKEVTLAQRKIAFQ 1621
Y+W G + + + K++ +
Sbjct: 1205 YMWVGTQTSQVEIKLSLK 1222
Score = 34.7 bits (78), Expect = 1.1
Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 33/160 (20%)
Query: 1470 DCFLLLSPHC---------CFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQTIE 1520
DC+++L + W+G A + +KA ++ A ++ CR T+
Sbjct: 526 DCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECR-----TVR 580
Query: 1521 EGINTHTHAAKDFWKLLGGQTSYQSAGDPK-----EDELYEAAIIETNCIYRLMDDKLVP 1575
E + + ++F ++ SY G ED Y + +Y + KL P
Sbjct: 581 EEMGDES---EEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYR---VYGKKNIKLEP 634
Query: 1576 DDDYWGKIP-KCSLLQPKEVLVFDFGSEVYVWHGKEVTLA 1614
+P K + L P+ V + D G ++YVW G + TL+
Sbjct: 635 -------VPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLS 667
>gi|14916473 scinderin isoform 2 [Homo sapiens]
Length = 468
Score = 106 bits (265), Expect = 2e-22
Identities = 125/555 (22%), Positives = 229/555 (41%), Gaps = 136/555 (24%)
Query: 1587 SLLQPKEVLVFDFGS--EVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPG 1644
++L +E + D G+ +++VW GK+ +RK A + A+ +N I L G
Sbjct: 28 AMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEG 87
Query: 1645 ECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKN----PGELAQHK 1700
ET +FK+ F DW + +S+ ++AQ K
Sbjct: 88 -------------------------GETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIK 122
Query: 1701 EDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEITSVSVDVWHIL 1760
+ P +D +++ S PQ A + S V++W +
Sbjct: 123 QIP------FDASKLHSSPQMAA-------------------QHNMVDDGSGKVEIWRVE 157
Query: 1761 EFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFFWQGRH 1820
++ + S G+F+ GD Y++ + + +G+ + + WQG +
Sbjct: 158 NNGRIQVDQNSYGEFYGGDCYIILYTY---------PRGQ-----------IIYTWQGAN 197
Query: 1821 STVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGG--MVVHSGRREEEEE 1875
+T E TSA +TV+LD G Q++V QGKEP L F+ ++ +G ++ +
Sbjct: 198 ATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ 257
Query: 1876 NVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCKAQAHTK 1935
RL+ VR + ++EV +SL S + VL + + Y+W
Sbjct: 258 APAPPTRLFQVRRNLASITRIVEVDVDANSLNS-NDVFVLKLPQNSGYIW---------- 306
Query: 1936 EVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCM-LQDP 1994
VG+ A+ + ++ A + + I EG EP FW++LG +K Y L +
Sbjct: 307 -VGKGASQEEEKGAEYVASVLKCKTLRI---QEGEEPEEFWNSLG--GKKDYQTSPLLET 360
Query: 1995 GSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP--FLQEDLYSAPQPALFLVDNH 2052
+ + PRL+ S+ +G F V+ +P F Q+DL + + L+D
Sbjct: 361 QAEDHPPRLYGCSNKTGRF-------------VIEEIPGEFTQDDL---AEDDVMLLDAW 404
Query: 2053 HEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK----GKNLKKPAPKSYLIHA 2108
++++W G N++ ++K ++++ Y + G++ + P +I
Sbjct: 405 EQIFIWIG--KDANEV----------EKKESLKSAKMYLETDPSGRDKRTPI---VIIKQ 449
Query: 2109 GLEPLTFTNMFPSWE 2123
G EP TFT F W+
Sbjct: 450 GHEPPTFTGWFLGWD 464
Score = 54.7 bits (130), Expect = 1e-06
Identities = 50/207 (24%), Positives = 92/207 (44%), Gaps = 36/207 (17%)
Query: 1427 NLTEQNSNNSAVPYKRLMLLQIKGRRHVQTRLVEPR--ASALNSGDCFLLLSP-HCCFLW 1483
N T + + P RL Q++ TR+VE A++LNS D F+L P + ++W
Sbjct: 249 NGTSKKGGQAPAPPTRLF--QVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 306
Query: 1484 VGEFANVIEKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY 1543
VG+ A+ E+ A +A++++ C+ IQ EE ++FW LGG+ Y
Sbjct: 307 VGKGASQEEEKGAEYVASVLK------CKTLRIQEGEE--------PEEFWNSLGGKKDY 352
Query: 1544 QSA------GDPKEDELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVF 1597
Q++ + LY + + + + DD L +V++
Sbjct: 353 QTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDD-----------LAEDDVMLL 401
Query: 1598 DFGSEVYVWHGKEVTLAQRKIAFQLAK 1624
D ++++W GK+ ++K + + AK
Sbjct: 402 DAWEQIFIWIGKDANEVEKKESLKSAK 428
>gi|63252913 gelsolin-like capping protein [Homo sapiens]
Length = 348
Score = 61.6 bits (148), Expect = 8e-09
Identities = 49/227 (21%), Positives = 100/227 (44%), Gaps = 22/227 (9%)
Query: 1432 NSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVI 1491
+ ++ P L Q+KG+++++ + N+GDCF+L F W G +N++
Sbjct: 126 HKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNIL 185
Query: 1492 EKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE 1551
E+ KA +LA I+ G ++ + +G + ++LG + + + G+P+E
Sbjct: 186 ERNKARDLALAIRDSERQG--KAQVEIVTDG-----EEPAEMIQVLGPKPALKE-GNPEE 237
Query: 1552 DELYEAAIIETNCIYRLMD-------DKLVPDDDYWGKIPKCSLLQPKEVLVFDFG--SE 1602
D + A + +Y++ D K+ + LL + V D G +
Sbjct: 238 DLTADKANAQAAALYKVSDATGQMNLTKVADSSPF-----ALELLISDDCFVLDNGLCGK 292
Query: 1603 VYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPL 1649
+Y+W G++ +R+ A Q+A+ + N + L G +P+
Sbjct: 293 IYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPI 339
Score = 46.2 bits (108), Expect = 4e-04
Identities = 69/320 (21%), Positives = 121/320 (37%), Gaps = 59/320 (18%)
Query: 1756 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1815
VW + + + +++ G F GD+Y+V + +E
Sbjct: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLV-------------------LHNGPEEVSHLHL 63
Query: 1816 WQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREE 1872
W G+ S+ E+G A++ V L+ ER Q + +QG E F+ F G+ G E
Sbjct: 64 WIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVES 123
Query: 1873 EEENVQSE-----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLWH 1926
+ +LY V+G+ + E A + S + ++ L N I+ W
Sbjct: 124 AFHKTSTGAPAAIKKLYQVKGKKNIRAT--ERALNWDSFNTGDCFILDLGQN---IFAWC 178
Query: 1927 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG----RR 1982
G K+ + R A I++ K + +G EP LG +
Sbjct: 179 GGKSNILERNKARDLALAIRDS-------ERQGKAQVEIVTDGEEPAEMIQVLGPKPALK 231
Query: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
+ + + D + A L+ +S ++G T+ V S PF E L S
Sbjct: 232 EGNPEEDLTADKANAQ-AAALYKVSDATGQMNLTK---------VADSSPFALELLIS-- 279
Query: 2043 QPALFLVDNH--HEVYLWQG 2060
F++DN ++Y+W+G
Sbjct: 280 -DDCFVLDNGLCGKIYIWKG 298
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 60.5 bits (145), Expect = 2e-08
Identities = 144/642 (22%), Positives = 224/642 (34%), Gaps = 102/642 (15%)
Query: 123 TLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESS-RDASSLYPGTETMGLRTCAGE 181
+LD + S S ++ S PDAVEK G S++ S DA P E
Sbjct: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER--------- 1418
Query: 182 SKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFTE 241
+S PE+ + R S + + L + + S S SG +
Sbjct: 1419 --------SSSASSPEMKDGL--PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD 1468
Query: 242 VPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINWP 301
+PR+P SR S D P+A P T +P+ S + +N
Sbjct: 1469 IPRTP------------SRGRSECDSSPEPKALPQTPRPR--------SRSPSSPELNNK 1508
Query: 302 SRVKVREKLVKEESARNSPELASESVTQRRH----QPAPVHYVSFQSEHSAFDRVPSKAA 357
RE+ E S + +A + QR Q V + E S D P A
Sbjct: 1509 CLTPQRERSGSESSV-DQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKA 1567
Query: 358 GSTRQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDS 417
TR P+R Q + +G + ++ ++ S + ++ V P G DS
Sbjct: 1568 -KTRTPLR---QRSRSGSSPEV---DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS 1620
Query: 418 ------PVLHVCESKAEE-EEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPED 470
P ++ +G G E + E K+ A G P+
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
Query: 471 PSRNEDFGKPAVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKP 530
SR + + S+ L + L ++ + + RT S P +
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
Query: 531 TGHNREASKKRKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDT 590
+ R ++ + +T S + P+ + L+ SRRE T
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE------------------KT 1782
Query: 591 KVSVAQLRSAFLASANACR-RPELKSRVERSAEGPG-----LPTGVERERGSRKPRRYFS 644
+ + + RS S + R R +SRV R G P E R S + RR S
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842
Query: 645 --PGESRKTSERFRTQPIT-SAERKESDRCT---SHSETPTVDDEEKVDERAKLSVAAKR 698
P SRK S R RT P R + T S S TP + R++ S ++R
Sbjct: 1843 RTPPTSRKRS-RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR---SRSRTSPVSRR 1898
Query: 699 LLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPIT 740
+S +V +RRSR+ A + R + RS T P+T
Sbjct: 1899 -------RSRSRTSVTRRRSRSRA--SPVSRRRSRSRTPPVT 1931
Score = 58.9 bits (141), Expect = 5e-08
Identities = 187/907 (20%), Positives = 325/907 (35%), Gaps = 134/907 (14%)
Query: 44 RASDPASPHIGRSNEEEETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAE 103
R+S P + RS ++ + S +S E S DS T+D++SL ++
Sbjct: 1100 RSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQS- 1157
Query: 104 RIARYKAERRRQLAEKYGLTLDPEADSEYLSRY-TKSRKEPDAVEKRGGKSDKQEESSRD 162
R+ +++ + L + T P + S + + R E V K ++ +E S
Sbjct: 1158 RLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG 1217
Query: 163 ASSLYPGTETMGLRTCAGESKDYALHVGDGSSDP--EVLLNIENQRRGQELSATRQAHDL 220
+S P T+ + + V + S +P ++L ++ ++ + S + ++
Sbjct: 1218 SS---PETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEV 1274
Query: 221 SPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKP 280
S T S +S V + S + S+G P SPE + + P
Sbjct: 1275 EERPAVSLTLDQSQSQASLEAV-------------EVPSMASSWGGPHFSPEHKELSNSP 1321
Query: 281 KHEWF----LQKDSEGDTPSLINWPSRVKVREKL---------------VKEESARNSPE 321
E L+ + G + +N +V+E L +KE+S R+S
Sbjct: 1322 LRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGH 1381
Query: 322 LASESVTQRRHQPAPVHYVSFQSEHS-------AFDRVPSKAAGST-----------RQP 363
+SE P V S S A R PS+ S+ R P
Sbjct: 1382 SSSEL------SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 364 IRGYVQPADTG----------HTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGD 413
R + G H+ +P + S S + P+P +L
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 414 GRDSPVLHVCESKAEEEEGEGEGEEKEED---VCFTEALEQSKKTLLALEGDGLVRSPED 470
SP +K + E G E D V T ++S+ SP++
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 471 PSRNEDFGKPAVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKP 530
S ++ T T Q+ + + + + R RS ++ +P +
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
Query: 531 TGHNREASKK--------RKVRTRSLSDFTGP-----PQLQALKYKDPASR------REL 571
+G + K R+ R+ S S GP ++ P SR R
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 572 ELPSSKTEGPYGEISMLDTKVSVAQLRSAFLA--SANACRRPELKSRV---ERSAEGPGL 626
P +K+ P S ++ S R A L+ S +A PE +SR R +
Sbjct: 1676 PEPKTKSRTPPRRRS---SRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS 1732
Query: 627 PTGVERERGSRKPRRYFSPGESRKTSERFRT--------QPITSAERKESDRCTSHSETP 678
P E+ R SR+ R SP ++ TS R R+ Q S R+E R T +
Sbjct: 1733 PEPAEKSRSSRRRRSASSP-RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791
Query: 679 TVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQP 738
+ R + S + R+ R S P R+ + RR + RS T P
Sbjct: 1792 --GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS---RRRRGRSRTPP 1846
Query: 739 ITTEEVVIAATEPIP-----ASCSGGTHPVMARLPSPTVARSAVQPARLQASAHQKALAK 793
T+ + + T P P + S TH +R +P ++R + +R + S + ++
Sbjct: 1847 -TSRKRSRSRTSPAPWKRSRSRASPATHR-RSRSRTPLISR---RRSRSRTSPVSRRRSR 1901
Query: 794 DQTNEGKELA-EQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQ---RRMNAR 849
+T+ + + + P S S + + + S+ S+ +TR R +R R +R
Sbjct: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR--SRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 850 YQTQPVT 856
+T PVT
Sbjct: 1960 SRTPPVT 1966
Score = 52.0 bits (123), Expect = 6e-06
Identities = 234/1179 (19%), Positives = 401/1179 (34%), Gaps = 183/1179 (15%)
Query: 126 PEADSEY-LSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAGESKD 184
PE Y L R + S + P +K+ K K++ R SS + S+
Sbjct: 165 PEPPKPYSLVRESSSSRSPTPKQKK--KKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 185 YALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFTEVPR 244
+ S P+ ++++R + S T A A S+S S S D+S +
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTT-PAPKSRRAHRSTSADSASSSDTSRSRSRS 281
Query: 245 SPKHAHSSSLQQAASRSPS-------FGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSL 297
+ H+++L A RSPS GD S ST +P ++ PS
Sbjct: 282 AAAKTHTTAL---AGRSPSPASGRRGEGDAPFSEPGTTSTQRPS-----SPETATKQPS- 332
Query: 298 INWPSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAA 357
S + ++K KE+SA P + E + PAP ++ E P
Sbjct: 333 ----SPYEDKDKDKKEKSATR-PSPSPERSSTGPEPPAPTPLLA---ERHGGSPQPLATT 384
Query: 358 GSTRQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDS 417
+++P+ P++ T P++PE + +S++++ P P T + S
Sbjct: 385 PLSQEPVN---PPSEASPTRDRSPPKSPEKLPQ----SSSSESSPPSPQPTKVSRHASSS 437
Query: 418 PVL-----------HVCESKAEEEEGEGEGE-EKEEDVCFTEALEQSKKTLLALEGDGLV 465
P + S + G + +K + + +S+ A G
Sbjct: 438 PESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS 497
Query: 466 RSP----EDPSRNEDFGKP-AVSTVTLEHQKELENVAQPPQAP----HQPTERTGRSEMV 516
R+P SR+ + + + + ++ PQ P + T+R GRS
Sbjct: 498 RTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSA 557
Query: 517 LYIQSEPVSQDAKPTGHNREASKKRKVRTRSLSDF-----TGPPQLQALKYKDPA--SRR 569
+S S+ G +R + R+ R+RS + + P + + + PA R
Sbjct: 558 RRGRSH--SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
Query: 570 ELELPSSKTEGPYGEISMLDTKVSVAQLRSAFLASANACRRPELKSRV-----ERSAEGP 624
P+ + + S A+ RS S RR +SR + P
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPAR-RSGRSRSRTPARRGRSRSRTPARRGRSRSRTP 674
Query: 625 GLPTGVERERG--------SRKPRRYFSP-------GESRKTSERFRTQPITSAERKESD 669
+G R R SR PRR S G S + + R + +S+ERK
Sbjct: 675 ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 670 RCTSHSETPTVDDEEKVD--------------ERAKLSVAAKRLLFREMEKSFDEQNVPK 715
R + E K +AK ++ +R L + P
Sbjct: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
Query: 716 RRSRNTA----VEQRLRRLQDRSLTQP------ITTEEVVIAATEPIPASCSGGTHPVMA 765
RRSR+ + + R + RS + P T +++ P P GT P
Sbjct: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP-KVKSGTPPRQG 853
Query: 766 RLPSPTVARSAVQPARLQA-SAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNK 824
+ SP +V P R + K +T + P + + + +
Sbjct: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
Query: 825 LSQPVSKAISTRNRIDTRQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVAS 884
QP KAI I RQR + P + + + P + S V S
Sbjct: 914 SPQPKVKAI-----ISPRQRSHSGSSSPSPSRV-------TSRTTPRRSRSVSPCSNVES 961
Query: 885 TVAPMY------AGDLRTKPPL----DHNASATDYKF-------SSSIENSDSPVRSILK 927
+ P Y + D + KP H+ S + Y S+ S SP
Sbjct: 962 RLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
Query: 928 SQAWQPLVEGSEN--KGMLREYGETESKRALTGRD-SGMEKYGSFEEAEASYPILNRARE 984
+ GS + G+ ES ++ G + ++ S P + ++
Sbjct: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081
Query: 985 GDSHKESKYAVPRRGSLERANPPITHLG------DEPKEFSMAKMNAQGNLDLRDRLPFE 1038
+SK +G R++ P+T L + EFS + M G + R +
Sbjct: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSD 1141
Query: 1039 EK---VEVENVMKRKFSLRAAEFGE-----PTSEQTGTAAGKTIAQTTAPVSWKPQDSSE 1090
N + + L AE E P + T + + + PV +P+ S
Sbjct: 1142 SSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESS-- 1199
Query: 1091 QPQEKLCKNPCAMFAAGEIKTPTGE--GLLDSPSKTMSIKERLALLKKSGEEDWRNRLSR 1148
+ ++TP E G SP KE+ + L S +++ L
Sbjct: 1200 ------------LVFKDTLRTPPRERSGAGSSP----ETKEQNSALPTSSQDE---ELME 1240
Query: 1149 RQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEER 1187
E + PA + + + S +K+ T + ES +EER
Sbjct: 1241 VVEKSEEPAGQILSHLS--SELKEMSTSNFESSPEVEER 1277
Score = 40.8 bits (94), Expect = 0.015
Identities = 52/196 (26%), Positives = 77/196 (39%), Gaps = 32/196 (16%)
Query: 155 KQEESSRDASSLYPGTETMGLRTCAGESKDYALHVGDGSS---DPEVLLNI--------- 202
K+ SS +SS + + + + S + +GSS PEV L
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 203 ENQRRGQ--ELSATRQAHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQAASR 260
E R G+ E + ++ S ++ SSS+ S S SS + S + SSS ++S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 261 SPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVKEESARNSP 320
SPS P P+A P PK K G+ S R +S R+S
Sbjct: 2648 SPSPAKP--GPQALPKPASPK------KPPPGERRS----------RSPRKPIDSLRDSR 2689
Query: 321 ELASESVTQRRHQPAP 336
L+ V +RR P P
Sbjct: 2690 SLSYSPVERRRPSPQP 2705
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 58.9 bits (141), Expect = 5e-08
Identities = 122/604 (20%), Positives = 221/604 (36%), Gaps = 85/604 (14%)
Query: 203 ENQRRGQELSATRQAHDLSPAAESSSTFSFSGRD-SSFTEVPRSPKHAHSSSLQQAASRS 261
++Q+R L + + S + S + S D S+ S + + + SRS
Sbjct: 119 QSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRS 178
Query: 262 PSFGDPQ----LSPEARPSTGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVKEESAR 317
S G PQ L+ S G H Q+ P NW S +V + +
Sbjct: 179 SSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA-NWDSPSRVPFSSGQHSTQS 237
Query: 318 NSPELASESVTQRRHQPAPVHYVSFQSEHS---AFDRVPSKAAGSTRQPIRGYVQPADTG 374
P L S+S + + A V + Q + + S++ G++ ++ P+
Sbjct: 238 FPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELK----PSSKA 293
Query: 375 HTAKLVTPETPENASECSWVASATQNVPK-----PPSLTVLEGDGRDSPVLHVCESKAEE 429
H KL P P +AS V+ + + + PP LT + + P +K +
Sbjct: 294 HLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQ 353
Query: 430 EEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGK------PAVS 483
+ G GE+K + T QSK L+ D + S ED +D K P +
Sbjct: 354 QSNFGTGEQKRYNPSKTSNGHQSKS---MLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSN 410
Query: 484 TVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKK--- 540
+ H E + ++ + H +E + S+ +SE S D++ ++ AS +
Sbjct: 411 SEPSHHNSEGADNSRDDSSSHSGSESSSGSDS----ESESSSSDSEANEPSQSASPEPEP 466
Query: 541 ---RKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSS---KTEGPYGEISMLDTKVSV 594
K + + + P ++ PAS + +PSS K EG T S
Sbjct: 467 PPTNKWQLDNWLNKVNPHKV------SPASSVDSNIPSSQGYKKEGREQGTGNSYTDTS- 519
Query: 595 AQLRSAFLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSER 654
P+ S + + G E RG +K SP +S T++R
Sbjct: 520 ---------------GPKETSSATPGRDSKTIQKGSESGRGRQK-----SPAQSDSTTQR 559
Query: 655 FRTQPITSAERKESDRCTS---------HSETPTVDDEEKVDERAKLSV-AAKRLLFREM 704
+ + + K++++ + SETP R K + +++ ++
Sbjct: 560 ---RTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKE 616
Query: 705 EKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVM 764
KS K++ ++T+ + R + T ++E +E +P S +P
Sbjct: 617 SKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE-----SESLPPSSQTPKYPES 671
Query: 765 ARLP 768
R P
Sbjct: 672 NRTP 675
Score = 45.4 bits (106), Expect = 6e-04
Identities = 110/555 (19%), Positives = 201/555 (36%), Gaps = 50/555 (9%)
Query: 111 ERRRQLAEKYGLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGT 170
+ + L + L+ ++D E T R P + + + + ++SRD SS + G+
Sbjct: 375 QSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS 434
Query: 171 ETMGLRTCAGE--SKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSS 228
E+ E S D + S+ PE N+ + H +SPA+ S
Sbjct: 435 ESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDS 494
Query: 229 TF-SFSGRDSSFTEVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQ 287
S G E + +S ++ +S +P + + G+ K
Sbjct: 495 NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKS----P 550
Query: 288 KDSEGDTPSLINWPSRVKVREKLVKEESARNSPELASES-VTQRRHQPAPVHYVSFQSEH 346
S+ T + K EK EE R ++ SE+ V P+ H + +
Sbjct: 551 AQSDSTTQRRTVGKKQPKKAEKAAAEE-PRGGLKIESETPVDLASSMPSSRHKAATKGSR 609
Query: 347 SAFDRVPSKAAGSTRQPIRGYVQPADTGHTAK-LVTPETPENASECSWVASATQNVPKPP 405
+ SK++ + Y + + ++ ++ +T + S+ S + PK P
Sbjct: 610 KPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP 669
Query: 406 SLTVLEGDGRDSPVLHVCESKAEEEEG------EGEGEEKEEDVCFTEALEQSKKTLLAL 459
+S V S EEE+ EEKE +E + ++ +
Sbjct: 670 ----------ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEP-DDRYPLIVKI 718
Query: 460 EGDGLVRSPEDPSRNEDFGKPAVSTVTLEHQKEL-----ENVAQPPQAPHQPTERTGRSE 514
+ + L R P P + + K V +H +E E V+ + H+ + SE
Sbjct: 719 DLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE 778
Query: 515 MVLYIQSEPVSQDAKPTGH----NREASKKRKVRTRS-LSDFTGPPQLQALKYKDPASRR 569
+P ++D GH NRE+SK+ + + L GP + K + + +R
Sbjct: 779 -----SKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKR 833
Query: 570 ELELPSS-KTEGPYGEISMLDTKVSVAQLRSAFLASANACRRPELKSRVERSAEG--PGL 626
+ SS K+ + + +K S + + + E+K + S+ P
Sbjct: 834 TISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSA 893
Query: 627 PTGVERERGSRKPRR 641
PT S KPRR
Sbjct: 894 PT-----LDSSKPRR 903
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.0 bits (110), Expect = 2e-04
Identities = 84/385 (21%), Positives = 143/385 (37%), Gaps = 54/385 (14%)
Query: 424 ESKAEEEEG-EGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKPAV 482
E +A+EEEG E EG E+EE E E+ K+ A E + + P + E
Sbjct: 475 EKEAKEEEGKEEEGGEEEE----AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA 530
Query: 483 STVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKKRK 542
+ E K V P +A P ++AK EA K
Sbjct: 531 KSPEKEEAKSPAEVKSPEKA------------------KSPAKEEAKSP---PEAKSPEK 569
Query: 543 VRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSAFL 602
+S ++ P K K PA + E + P+ + + + S A+ +S
Sbjct: 570 EEAKSPAEVKSPE-----KAKSPA-KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623
Query: 603 ASANA---CRRPE-LKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQ 658
A + + PE KS + A+ P E+E ++ P + SP ++ S
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKS 682
Query: 659 PITSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRS 718
P+ AE K ++ S V +E K E+AK V + + + E+ ++
Sbjct: 683 PV-KAEAKSPEKAKS-----PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736
Query: 719 RNTAVEQ----RLRRLQDRSLTQPITTEEVVIAATE----PIPASCSGGTHPVMARLPSP 770
++ E+ + +++ T + + E A E P PV + SP
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796
Query: 771 TVARSAVQPARLQASAHQKALAKDQ 795
A+S P + A A +K + K +
Sbjct: 797 EKAKS---PLKEDAKAPEKEIPKKE 818
Score = 33.9 bits (76), Expect = 1.8
Identities = 57/292 (19%), Positives = 107/292 (36%), Gaps = 13/292 (4%)
Query: 918 SDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSFEEAEASYP 977
S+ ++ + KS+ +VE + + E E ++ + E+ G EEAE
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE 499
Query: 978 ILNR--AREGDS-HKESKYAVPRRG-SLERANPPITHLGDEPKEF---SMAKMNAQGNLD 1030
A E S KE+K V S A P P E AK A+
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 1031 LRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSSE 1090
EK E ++ + K +A + ++ A A++ K ++
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK 619
Query: 1091 QPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRRQ 1150
P ++ K+P + + + K+PT E SP K S ++ A + + + +
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEE-AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 1151 EGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEE-----RKQLITVREEA 1197
+ + + E +S +K+ +++ ++E K V+EEA
Sbjct: 679 KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 730
Score = 31.6 bits (70), Expect = 9.0
Identities = 89/480 (18%), Positives = 171/480 (35%), Gaps = 35/480 (7%)
Query: 926 LKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSFEEAEASYPILNRAREG 985
+KS+ +VE SE + ++ E E++ E+ EE EA + EG
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVT--------EEVTEEEEKEA------KEEEG 483
Query: 986 DSHKESKYAVPRRGSLERANPPITHLGDEPKEF-SMAKMNAQGNLDLRDRLPFEEKVEVE 1044
+ + G E +PP KE S K A+ + + EK E +
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKS----PEKEEAK 539
Query: 1045 NVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSSEQPQEKLCKNPCAMF 1104
+ + K +A + ++ A + +P K + ++ P ++ K+P
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599
Query: 1105 AAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGE-EDWRNRLSRRQEGGKAPASSLHTQ 1163
+ + K+P E +KE K E + S +E K+P + +
Sbjct: 600 SPEKAKSPVKEEAKSPAEAKSPVKEE---AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 1164 EAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDSTQFTVAGRMVKKGL 1223
+ +K + + + E+ K + ++ + ++ A VK+
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 1224 ASP-TAITPVASPICGKTRGTTPVSKPLEDIE--ARPDMQLESDLKLDRLET----FLRR 1276
SP A +PV + +PV + + E P+ D+K +T R
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776
Query: 1277 LNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDEDFDVIFDP 1336
+K ++ + KS ++ P ++ A +SPV+ +E +
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Query: 1337 YAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFMESKRMKVE 1396
PK E K PK + K+ K A +++ + E++ A + K KVE
Sbjct: 837 EPPK---KAEEEKAPATPK--TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 46.2 bits (108), Expect = 4e-04
Identities = 106/541 (19%), Positives = 181/541 (33%), Gaps = 68/541 (12%)
Query: 152 KSDKQEESSRDASSLYPGTETMGLRTCAGESKDYALHVGDGSSDPEVL----LNIENQRR 207
K K E+ DA + +T T AG A G+G S+ E+ +
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQ 1815
Query: 208 GQELSATRQAHDLSPAAESSSTFSFSGR---DSSFTEVPRSPKHAHSSSLQQAASRSPSF 264
G+ + Q S AE G +S E P + A + +A S
Sbjct: 1816 GEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAE-GEAQPESEDV 1874
Query: 265 GDPQLSPEARPSTGK---PKHEWFLQKDSEGDTPSLINWPSRVKVREKLVKEESARNSPE 321
P+ EA+P + P+ EW +Q +SEG ++ + E + PE
Sbjct: 1875 EAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE 1934
Query: 322 L-------ASESVTQRRHQPAPVHYV--SFQSEHSA---FDRVPSKAAGSTRQPIRGYVQ 369
A E+ + Q P V S ++E A + V + Q G Q
Sbjct: 1935 SEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQ 1994
Query: 370 PADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVLHVCESKAEE 429
P A E E E + + PK +G ++ E + E
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPK--------SEGEEAQ-----EVEGET 2041
Query: 430 EEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKPAVSTVTLEH 489
++ EG+ + + + V EA E+++ E +G V+ E + E A
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQ------EAEGEVQEAEGEAHPESEDVDA-------- 2087
Query: 490 QKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASK-----KRKVR 544
+E E AQP + E G ++ I++ +A+P EA + + +
Sbjct: 2088 -QEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Query: 545 TRSLSDFTG--PPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSAFL 602
D G P+ + ++ ++ + EL + GE + +
Sbjct: 2147 GVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQ 2206
Query: 603 ASANACRRPELKSRVE--------RSAEGPGLPTGVERERGSRK--PRRYFSPGESRKTS 652
PE + + AEG P +G +K P+ G+S + S
Sbjct: 2207 PELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEAS 2266
Query: 653 E 653
E
Sbjct: 2267 E 2267
Score = 32.3 bits (72), Expect = 5.3
Identities = 59/278 (21%), Positives = 98/278 (35%), Gaps = 43/278 (15%)
Query: 35 LEEDTPRYMRASDPASPHIGRSNEEEETSDSSLEKQ-TRSKYCTETSGVHGDSPYGSGTM 93
+E +T + + P S + EEE ++ E Q + E+ V G
Sbjct: 2037 VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP 2096
Query: 94 DTHSLES--------KAERIARYKAERRRQLAEKYGLTLDPEADSEYLSRYTKSRKEPDA 145
++ +E+ KAE I + E Q E G+ PEA+ E ++ E +
Sbjct: 2097 ESEGVEAPEAEGEAQKAEGIEAPETEGEAQ-PESEGIEA-PEAEGE-------AQPESEG 2147
Query: 146 VEKRGGKSDKQEESS--------RDASSLYPGTETMGLRTCAGESKDYALHVGDGSSDPE 197
VE + + + Q ES +A G E A E++ A +G PE
Sbjct: 2148 VEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE-------APEAEGEAQPESEGIEAPE 2200
Query: 198 VLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQA 257
+ + G E +P AE + G ++ E P+ + ++
Sbjct: 2201 AEGEAQPELEGVE----------APEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 258 ASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTP 295
S S GD Q + S+ P+ GDTP
Sbjct: 2251 GSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 45.8 bits (107), Expect = 5e-04
Identities = 146/643 (22%), Positives = 230/643 (35%), Gaps = 102/643 (15%)
Query: 249 AHSSSLQQAASRSPSFGDPQLSPEARPST------------GKPKHEW-FLQKDSEGDTP 295
A + L++ +S DP L+PE P+ G K + LQK E +
Sbjct: 1723 AEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQK 1782
Query: 296 SLINWPSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSK 355
P RVK +E + K+ + R P AS S+ RH P + HS S
Sbjct: 1783 GRSKLPIRVKGKEDVPKKTTHRPHP-AASPSLKSERHAPGSPSPKT--ERHSTL----SS 1835
Query: 356 AAGSTRQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGR 415
+A + R P P + +P +P +E AS++ K ++ R
Sbjct: 1836 SAKTERHP------PVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTER 1889
Query: 416 DSPVLHVCESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNE 475
SPV + G+ +++ +++K G R P PS
Sbjct: 1890 HSPVSSTKTERHPPVSPSGKTDKRPP----VSPSGRTEKHPPVSPGRTEKRLPVSPSGRT 1945
Query: 476 DFGKPAVSTV--TLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGH 533
D +P VST T +H + Q P PT +T R E ++ V + K
Sbjct: 1946 DKHQP-VSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIE-----ETMSVRELMKAFQS 1999
Query: 534 NREASKKRKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVS 593
++ SK + TG + ++ K K P + ++ + K +GP
Sbjct: 2000 GQDPSKHK----------TGLFEHKSAKQKQPQEKGKVRV--EKEKGPI----------- 2036
Query: 594 VAQLRSAFLASANACRRPELKSRVERSAEGPGLP-TG-VERERGSRKP----RRYFSPGE 647
+R K+ + G LP TG E +RG R ++ + G
Sbjct: 2037 -------------LTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDAAGG 2083
Query: 648 SRKTSERFRTQPITSAERKESDRCTSHSETPTVDDEEKVDERA--KLSVAAKRLL---FR 702
K +P+ S +ES R SE P E+ DE+ L ++ R F
Sbjct: 2084 KEKVLSHKIPEPVQSVPEEESHR---ESEVP---KEKMADEQGDMDLQISPDRKTSTDFS 2137
Query: 703 EMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPI-TTEEVVIAATEPIPASC--SGG 759
E+ K E N ++ R + ++ + D+ LT P TT + E +PA SG
Sbjct: 2138 EVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGA 2197
Query: 760 THPVMARLPSPTVARSAVQPARLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKL 819
L + VA S L Q + + +EG LAE E +LS + K
Sbjct: 2198 LDGSSESLKNEGVAGSPC--GSLMEGTPQISSEESYKHEG--LAETPETSPESLSFSPK- 2252
Query: 820 ALFNKLSQPVSKAISTRNRIDTRQRRMNARYQTQPVTLGEVEQ 862
Q ST+ T R T+ +T G E+
Sbjct: 2253 ---KSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEER 2292
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 45.4 bits (106), Expect = 6e-04
Identities = 49/190 (25%), Positives = 75/190 (39%), Gaps = 25/190 (13%)
Query: 265 GDPQLSPEARPSTGKPKHEWFLQKDSEGD--TPSLINWPSRVKVREKLVKEESARNSPEL 322
GD P RP + W++ S G P LI V +R L+ + S R P
Sbjct: 152 GDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIM--ILVYLRIYLIAKRSNRRGPRA 209
Query: 323 ASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAAGSTRQPIRGYVQPADTGHTAKLVTP 382
QP P H + S ++P+ A+ ++ + + G+ + T +
Sbjct: 210 KGGPGQGESKQPRPDHGGALASA-----KLPALASVASAREVNGHSKS-----TGEKEEG 259
Query: 383 ETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVLHVCESKAEEEEGEGEGEEKEED 442
ETPE+ T PPS L G+ VC + E+E E E EE+EE+
Sbjct: 260 ETPED----------TGTRALPPSWAALPNSGQGQKE-GVCGASPEDEAEEEEEEEEEEE 308
Query: 443 VCFTEALEQS 452
C +A+ S
Sbjct: 309 ECEPQAVPVS 318
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 44.7 bits (104), Expect = 0.001
Identities = 78/378 (20%), Positives = 149/378 (39%), Gaps = 42/378 (11%)
Query: 369 QPADTGHTAKLVTPETPENASECSW------VASATQNVPKPPSLTVLEGDGRDSPVLHV 422
+P + PE PEN SW +A++T N PKP + ++P
Sbjct: 377 EPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPN-PKPAA------SSPETPSAGQ 429
Query: 423 CESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPE-DPSRNEDFGKPA 481
E+K ++ +G E + K+ + L+ + + E P R++ P
Sbjct: 430 QEAKTDQADGPREPPQS------ARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPC 483
Query: 482 VSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYI-QSEPVSQDAKPTGHNREASKK 540
++ + + + Q Q PT RS M +I ++ P+ D K + +E +
Sbjct: 484 PASKVVRPLRTFLHTVQRNQMLMTPTS-APRSVMKSFIKRNTPLRMDPKCSFVEKERQRL 542
Query: 541 RKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSA 600
+R + ++ QL+ K ++ RR LE K E ++ L + V Q++
Sbjct: 543 ENLRRKEEAE-----QLRRQKVEED-KRRRLEEVKLKREERLRKV--LQARERVEQMKEE 594
Query: 601 FLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQPI 660
+ ++ + E++ E +++ ++K + + + + R R
Sbjct: 595 KKKQIEQ-KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 661 TSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLL-FREMEKSFDEQNVPKRRSR 719
ER+ H E EE+ ER + + AKRL RE E+ E+ +RR +
Sbjct: 654 EEEERR-------HQELLQKKKEEE-QERLRKAAEAKRLAEQREQERREQERREQERREQ 705
Query: 720 NTAVEQRLRRLQDRSLTQ 737
++ RR Q+R L +
Sbjct: 706 ERREQE--RREQERQLAE 721
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 44.3 bits (103), Expect = 0.001
Identities = 89/400 (22%), Positives = 144/400 (36%), Gaps = 50/400 (12%)
Query: 32 HRLLEEDTPRYMRASDPASPHIGRSNEEEETSDSSLEKQTRSKYCTETSGVHGDSPYG-S 90
HR R S S H GRS EE + S ++ S+ C++T + DSP S
Sbjct: 186 HRCPSRSQSSESRPSSCESRHRGRSPEEGQKS-----RRRHSRRCSKT--LCKDSPEAQS 238
Query: 91 GTMDTHSLESKAERIARYKAERRRQLAEKYGLTLDPEADSEYLSRYTKSRKE---PDAVE 147
+ L+ AR A+ + T P S S+ S + P + +
Sbjct: 239 SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQ 298
Query: 148 KRGGKSDKQEESSRDASSLYPGTETMGLRTCAGESKDYALHVGDGSSDPEVLLNIENQRR 207
+S QE+ S G + +G S + G+ +L N+ R
Sbjct: 299 TSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGA----MLENLSPTSR 354
Query: 208 GQELS---------ATRQAHDLSPAAESSSTFSFSGRDSSFTEV-----------PR-SP 246
G+E A + L P+ SS R SS+ PR SP
Sbjct: 355 GRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASP 414
Query: 247 KHAHS---SSLQQAASRSPSFGDP--QLSPEARPSTGKPKHEWFLQKDSEGDTPSLINWP 301
++ S SS +++ SRSPS+ + SP +R S + + S P
Sbjct: 415 RYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKD 474
Query: 302 SRVKVREKLVKEESA--------RNSP-ELASESVTQRRHQPAPVHYVSFQSEHSAFDRV 352
S+ + RE+ + + R+SP L + +T R +P P + S S S
Sbjct: 475 SQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTS 534
Query: 353 PSKAAGSTRQPIRGYVQPADTGHTAKLVTPETPENASECS 392
++ S+R R Y + + + T ++S S
Sbjct: 535 SWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRS 574
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 43.9 bits (102), Expect = 0.002
Identities = 163/838 (19%), Positives = 272/838 (32%), Gaps = 121/838 (14%)
Query: 137 TKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAGESKDYALHVGDGSSDP 196
T + + P E+ K + R+ S+ P T + AG+ H+ + P
Sbjct: 174 TDNHEAPPTSEENSSNQGK-DPMIRNQRSVDPADSTTTHKESAGKK-----HI---TPAP 224
Query: 197 EVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQ 256
+ +N G+ + P +S ST D + T ++ H+S Q
Sbjct: 225 KSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL-----DKTSTSSHKTTTSFHNSGNSQ 279
Query: 257 AASRSPSF---------------GDPQLSPEARPSTGKPKHEWFLQKDSE---------- 291
+S SF G P+ S + S + L K ++
Sbjct: 280 TKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANE 339
Query: 292 ------------GDTPSLINWPSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHY 339
G T + N PS + E +E +A + L+ T+ R + A
Sbjct: 340 LTQSLAEPTEHGGRTANENNTPSPAEPTEN--RERTANENTTLSPAEPTENRERTA---- 393
Query: 340 VSFQSEHSA-FDRVPSKAAGSTRQPIRGYVQPADTGHTAKLVTPETPENASECSWVASAT 398
+E++A F P++ T T H + T + +E + T
Sbjct: 394 ----NENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERT 449
Query: 399 QNVPKPPSLTVLEGDGRDSPVLH--VCESKAEE-EEGEGEGEEKEEDVCF-TEALEQSKK 454
N PS G +P + S AE E GE E E E ++
Sbjct: 450 ANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRER 509
Query: 455 TLLALEGDGLVRSPEDPSRNEDFGKPAVSTVT-LEHQKELENVAQPPQAPHQPTERTGRS 513
T + SP P+ N + +T++ +E + E A P P E T
Sbjct: 510 TA----NENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTP-SPAEPTENG 564
Query: 514 EMVLYIQSEPVSQDAKPTGHNREASKKRKVRTRSLSDFTGPPQLQALKYKD-PASRRELE 572
+ + + S A+PT H RT ++ T P + + ++ A+ +
Sbjct: 565 QRTPFANEKTTSSSAEPTEHGE--------RTPLANENTTPSPAEPTENRERTANEKTTP 616
Query: 573 LPSSKTE-GPYGEISMLDTKVSVAQLRSAFLASANACRRPELKSRVERSAEGPGLPTGVE 631
P+ TE G ++ T S+A+ + N R P + S+ P E
Sbjct: 617 SPAEPTENGDRTPLANEKTTPSLAE------PTENGQRTPFANEKTTSSSAEP-----TE 665
Query: 632 RERGSRKPRRYFSPGESRKTSERFRTQ----------PITSAERKESDRCTSHSETPTVD 681
E + +P + T R RT P + E +++ T PT +
Sbjct: 666 HEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTEN 725
Query: 682 DEEKVDERAKLSVA-----AKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLT 736
E +E+ S A +R F EK+ P T + L T
Sbjct: 726 RERTANEKTTSSPAEPTENGQRTPFAN-EKTTSSSAEPTEHGERTPLANENTTLSPAGPT 784
Query: 737 QPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPARLQ-ASAHQKALAKDQ 795
+ E T P PA + +P+ A+ R A+ +
Sbjct: 785 E--NRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEP 842
Query: 796 TNEGKELAEQGEPDSST----LSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNARYQ 851
T GK E +S+ AE+ L N+ + S A T NR T + ++
Sbjct: 843 TENGKRTPFANEKTTSSSAEPTEHAERTPLANE-NTTSSPAEPTENRERTANEK-TTQFP 900
Query: 852 TQPVTLGEVEQVQSGKLIPFSPAVNTS-VSTVASTVAPMYAGDLRTKPPL--DHNASA 906
+P E + P P N + +T++P + PL D N A
Sbjct: 901 AEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQA 958
Score = 36.6 bits (83), Expect = 0.28
Identities = 141/680 (20%), Positives = 229/680 (33%), Gaps = 98/680 (14%)
Query: 479 KPAVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREAS 538
KP ++ T++H+ +N PP + + + G+ M+ +S V T H A
Sbjct: 160 KPTGNSKTIDHKSSTDNHEAPPTS-EENSSNQGKDPMIRNQRS--VDPADSTTTHKESAG 216
Query: 539 KKRKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGE-ISMLD-TKVSVAQ 596
KK T P+ + K + + S KT P + +S LD T S +
Sbjct: 217 KKH---------ITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHK 267
Query: 597 LRSAFLASANACRRPELKSRVER-------SAEGPGLPTGVERERGSR----------KP 639
++F S N+ + + S E+ + + G P E+ SR K
Sbjct: 268 TTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKT 327
Query: 640 RRYFSPGESRKTSERFRTQPITSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRL 699
+ S + +P R ++ T PT + E +E LS A
Sbjct: 328 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPT- 386
Query: 700 LFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGG 759
E++ +E P ++R +T T TE + +
Sbjct: 387 --ENRERTANENTAPFPAGPT----------ENREMTANENTTLFPAEPTEHGERTANEN 434
Query: 760 THPVMARLPSPTVARSAVQ-----PARLQASAHQKALAKDQ-TNEGKELAEQGE-----P 808
T P A P+ R+A + PA + A D+ T+ E E GE
Sbjct: 435 TTPSPAE-PTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLAN 493
Query: 809 DSSTLSLAE----KLALFNKLSQPVSKAISTRNR-------------IDTRQRRMNARYQ 851
+++T S AE + N+ + P S A T NR T R A +
Sbjct: 494 ENTTPSPAEPTENRERTANENTTP-SPAGPTENRETTANEKTTLSPVEPTENRETTANEK 552
Query: 852 TQPVTLGEVEQVQSGKLIPFSPAVNTSVS---TVASTVAPMYAGDLRTKPPLD----HNA 904
T P E ++G+ PF+ TS S T P+ A + T P +
Sbjct: 553 TTP---SPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPL-ANENTTPSPAEPTENRER 608
Query: 905 SATDYKFSSSIENSDSPVRSILKSQAWQP-LVEGSEN--KGMLREYGETESKRALTGRDS 961
+A + S E +++ R+ L ++ P L E +EN + T S T +
Sbjct: 609 TANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEE 668
Query: 962 GMEKYGSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMA 1021
+ P NR R + + A P AN T EP E
Sbjct: 669 RTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRER 728
Query: 1022 KMNAQGNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPT----SEQTGTAAG------ 1071
N + + ++ N S E GE T T + AG
Sbjct: 729 TANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRE 788
Query: 1072 KTIAQTTAPVSWKPQDSSEQ 1091
+T + T P +P ++ E+
Sbjct: 789 RTANEKTTPFPAEPTENRER 808
>gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 43.9 bits (102), Expect = 0.002
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 2167 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 358 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405
>gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Homo
sapiens]
Length = 358
Score = 43.9 bits (102), Expect = 0.002
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 2167 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 311 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 358
>gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 43.9 bits (102), Expect = 0.002
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 2167 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 336 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383
>gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 43.9 bits (102), Expect = 0.002
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 2167 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 336 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,466,696
Number of Sequences: 37866
Number of extensions: 4241446
Number of successful extensions: 15286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 295
Number of HSP's that attempted gapping in prelim test: 13796
Number of HSP's gapped (non-prelim): 1403
length of query: 2214
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2096
effective length of database: 13,779,330
effective search space: 28881475680
effective search space used: 28881475680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.