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Search of human proteins with 148833484
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148833484 poly(rC) binding protein 2 isoform c [Homo
sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 649 0.0
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 643 0.0
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 632 0.0
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 627 e-180
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 626 e-180
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 620 e-178
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 612 e-175
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 531 e-151
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 503 e-143
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 446 e-125
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 367 e-101
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 367 e-101
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 283 2e-76
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 106 3e-23
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 106 3e-23
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 106 3e-23
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 86 4e-17
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 86 4e-17
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 78 1e-14
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 77 2e-14
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 77 2e-14
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 75 1e-13
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 73 3e-13
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 72 5e-13
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 71 2e-12
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 70 2e-12
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 68 1e-11
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 55 9e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 55 9e-08
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 649 bits (1673), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV 240
KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV 240
Query: 241 KGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 300
KGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ
Sbjct: 241 KGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 300
Query: 301 VTITGSAASISLAQYLINVRLSSETGGMGSS 331
VTITGSAASISLAQYLINVRLSSETGGMGSS
Sbjct: 301 VTITGSAASISLAQYLINVRLSSETGGMGSS 331
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 643 bits (1658), Expect = 0.0
Identities = 331/335 (98%), Positives = 331/335 (98%), Gaps = 4/335 (1%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESS 236
PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESS
Sbjct: 181 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESS 240
Query: 237 SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS 296
SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS
Sbjct: 241 SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS 300
Query: 297 TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 331
TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS
Sbjct: 301 TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 335
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 632 bits (1631), Expect = 0.0
Identities = 331/362 (91%), Positives = 331/362 (91%), Gaps = 31/362 (8%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 210 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 269
KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
Query: 270 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 329
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
Query: 330 SS 331
SS
Sbjct: 361 SS 362
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 627 bits (1616), Expect = e-180
Identities = 331/366 (90%), Positives = 331/366 (90%), Gaps = 35/366 (9%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 265
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 300
Query: 266 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 325
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 301 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 360
Query: 326 GGMGSS 331
GGMGSS
Sbjct: 361 GGMGSS 366
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 626 bits (1615), Expect = e-180
Identities = 330/362 (91%), Positives = 330/362 (91%), Gaps = 32/362 (8%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 210 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 269
KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLIGCII
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLIGCII 299
Query: 270 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 329
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 300 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 359
Query: 330 SS 331
SS
Sbjct: 360 SS 361
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 620 bits (1600), Expect = e-178
Identities = 330/366 (90%), Positives = 330/366 (90%), Gaps = 36/366 (9%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 265
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
Query: 266 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 325
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
Query: 326 GGMGSS 331
GGMGSS
Sbjct: 360 GGMGSS 365
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 612 bits (1577), Expect = e-175
Identities = 318/331 (96%), Positives = 318/331 (96%), Gaps = 13/331 (3%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV 240
KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS--------- 231
Query: 241 KGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 300
AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ
Sbjct: 232 ----AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 287
Query: 301 VTITGSAASISLAQYLINVRLSSETGGMGSS 331
VTITGSAASISLAQYLINVRLSSETGGMGSS
Sbjct: 288 VTITGSAASISLAQYLINVRLSSETGGMGSS 318
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 531 bits (1367), Expect = e-151
Identities = 285/358 (79%), Positives = 305/358 (85%), Gaps = 29/358 (8%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175
KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 176 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 213
IPY+P P+SSPVI AGGQ AY+IQGQ+ I DL KL+Q
Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240
Query: 214 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 273
+A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+LIGCIIGRQG
Sbjct: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG 299
Query: 274 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 331
A INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE GMG S
Sbjct: 300 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK-GMGCS 356
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 503 bits (1296), Expect = e-143
Identities = 263/338 (77%), Positives = 293/338 (86%), Gaps = 8/338 (2%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPD-LTKLHQLAMQQSHF-PMTHGNTGFSG----IE 234
KP+S+PVIFAGGQAYTIQGQYAIP PD LTKLHQLAMQQ+ F P+ N F G +
Sbjct: 213 KPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 272
Query: 235 SS--SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 292
SS + + G +GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 273 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 332
Query: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 330
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 333 TEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 370
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 446 bits (1148), Expect = e-125
Identities = 241/337 (71%), Positives = 269/337 (79%), Gaps = 32/337 (9%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHF-PMTHGNTGFSG----IES 235
AYTIQGQYAIP PDLTKLHQLAMQQ+ F P+ N F G + S
Sbjct: 201 -------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS 247
Query: 236 S--SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 293
S + + G +GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 248 SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANAT 307
Query: 294 EGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 330
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 308 EGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 344
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 367 bits (941), Expect = e-101
Identities = 195/329 (59%), Positives = 242/329 (73%), Gaps = 21/329 (6%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWA 245
V+ + Q +++QGQY A+ ++TKL QL+ SH + ++P V
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVV---P 233
Query: 246 GLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITG 305
GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITG
Sbjct: 234 GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITG 293
Query: 306 SAASISLAQYLINVRL---SSETGGMGSS 331
S SI+LAQYLI L S +GG SS
Sbjct: 294 SPVSIALAQYLITACLETAKSTSGGTPSS 322
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 367 bits (941), Expect = e-101
Identities = 195/329 (59%), Positives = 242/329 (73%), Gaps = 21/329 (6%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWA 245
V+ + Q +++QGQY A+ ++TKL QL+ SH + ++P V
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVV---P 233
Query: 246 GLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITG 305
GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITG
Sbjct: 234 GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITG 293
Query: 306 SAASISLAQYLINVRL---SSETGGMGSS 331
S SI+LAQYLI L S +GG SS
Sbjct: 294 SPVSIALAQYLITACLETAKSTSGGTPSS 322
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 283 bits (723), Expect = 2e-76
Identities = 167/349 (47%), Positives = 209/349 (59%), Gaps = 76/349 (21%)
Query: 42 ESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLR 101
+S ARI ISEG+CPERI T+ G T A+F A +MI KL+ED+ ++ N SRPPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 102 LVVPASQCGSLIGKGGCKIK---EIR---------------------------------- 124
LV+PASQCGSLIGK G KIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 125 ------------------ESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVM 166
++TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 167 LESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTH 225
LESPPKG TIPY P S V+ + Q +++QGQY A+ ++TKL QL+ SH
Sbjct: 192 LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLS---SH----- 243
Query: 226 GNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGA 285
+ ++P V GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA
Sbjct: 244 ------AVPFATPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGA 294
Query: 286 QIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGMGSS 331
IKI N EG+ +R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 295 HIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 343
Score = 45.1 bits (105), Expect = 9e-05
Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 103 VVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI------- 155
+VP G +IG+ G KI EIR+ +GA +++ G+ + ER +TI G P SI
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIALAQYLI 326
Query: 156 ---IECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAG--GQAYTI 197
+E K S P + P+ P ++ P G G Y I
Sbjct: 327 TACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAI 373
Score = 35.4 bits (80), Expect = 0.071
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 25 VGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
+G +IG++G + ++R+ SGA I I +EG ER +T+ G +I A +I LE
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332
Query: 82 DISSSMTNSTAAS-------RPPVTLRLVVPASQCGS 111
S+S ++A PP+T P G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 106 bits (265), Expect = 3e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 74.7 bits (182), Expect = 1e-13
Identities = 44/99 (44%), Positives = 58/99 (58%), Gaps = 2/99 (2%)
Query: 219 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 278
S + M + G SG + S +G + L TT ++TIP DL G IIG+ G +I +
Sbjct: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
Query: 279 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 317
IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 59/211 (27%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTAT-------- 120
Query: 218 QSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGRQGAK 275
S P +ES + E Y + G D + L I L G IIG +GAK
Sbjct: 121 -SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAK 166
Query: 276 INEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
I E+R+ + IK+ STDR V I G
Sbjct: 167 IKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 106 bits (265), Expect = 3e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 75.5 bits (184), Expect = 6e-14
Identities = 45/108 (41%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
Query: 219 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 278
S + M + G SG + S +G + L TT ++TIP DL G IIG+ G +I +
Sbjct: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
Query: 279 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 59/211 (27%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTAT-------- 120
Query: 218 QSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGRQGAK 275
S P +ES + E Y + G D + L I L G IIG +GAK
Sbjct: 121 -SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAK 166
Query: 276 INEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
I E+R+ + IK+ STDR V I G
Sbjct: 167 IKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 106 bits (265), Expect = 3e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 74.7 bits (182), Expect = 1e-13
Identities = 44/99 (44%), Positives = 58/99 (58%), Gaps = 2/99 (2%)
Query: 219 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 278
S + M + G SG + S +G + L TT ++TIP DL G IIG+ G +I +
Sbjct: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
Query: 279 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 317
IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 59/211 (27%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTAT-------- 120
Query: 218 QSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGRQGAK 275
S P +ES + E Y + G D + L I L G IIG +GAK
Sbjct: 121 -SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAK 166
Query: 276 INEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
I E+R+ + IK+ STDR V I G
Sbjct: 167 IKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 86.3 bits (212), Expect = 4e-17
Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
Query: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
Query: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
+ + G+ L T T+A ++ +
Sbjct: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
Query: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235
P +++ ++ + G A L LA T G+ G S
Sbjct: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 405
Query: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292
++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 406 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 463
Query: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 464 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 497
Score = 70.9 bits (172), Expect = 2e-12
Identities = 52/198 (26%), Positives = 94/198 (47%), Gaps = 41/198 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
I +K+ E + SS T + ++ P+T
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSI 155
++++VP S G +IGKGG +K + E +GA VQ++ D + N ER +T++G P+
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQN 230
Query: 156 IECVKQICVVMLESPPKG 173
+ V+ I + E P G
Sbjct: 231 RKAVELIIQKIQEDPQSG 248
Score = 32.0 bits (71), Expect = 0.78
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 86.3 bits (212), Expect = 4e-17
Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
Query: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
+ + G+ L T T+A ++ +
Sbjct: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
Query: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235
P +++ ++ + G A L LA T G+ G S
Sbjct: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 381
Query: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292
++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 382 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 439
Query: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 440 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473
Score = 74.7 bits (182), Expect = 1e-13
Identities = 50/174 (28%), Positives = 91/174 (52%), Gaps = 17/174 (9%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
Query: 122 EIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173
+ E +GA VQ++ D + N ER +T++G P+ + V+ I + E P G
Sbjct: 172 AVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
Score = 32.0 bits (71), Expect = 0.78
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 78.2 bits (191), Expect = 1e-14
Identities = 87/368 (23%), Positives = 147/368 (39%), Gaps = 86/368 (23%)
Query: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
Query: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE---------------------- 168
V + LP ++ + I G + + + + ++ E
Sbjct: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
Query: 169 --SPPK---------------------GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
S P+ GV I ++P SP +A + G
Sbjct: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP-----ERAAQVMG-----P 306
Query: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTIPN 262
PD + H + GF G+ ++ +G + G Q ++ T+P
Sbjct: 307 PDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVPA 363
Query: 263 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINV 319
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 364 DKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
Query: 320 RLSSETGG 327
++ G
Sbjct: 424 KVGGTNLG 431
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/182 (31%), Positives = 83/182 (45%), Gaps = 22/182 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
Query: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
Query: 185 SP 186
P
Sbjct: 443 QP 444
Score = 49.3 bits (116), Expect = 5e-06
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 131 VQVAGDMLPNSTERAITIAGIP 152
+Q D S ERA + G P
Sbjct: 287 IQFKPDD-GISPERAAQVMGPP 307
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
Query: 315 YLI 317
L+
Sbjct: 139 RLL 141
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/260 (21%), Positives = 103/260 (39%), Gaps = 28/260 (10%)
Query: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
Query: 155 IIECVKQICVVMLESPPKG----------VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIP 204
IE K++ +++ G TI P+S + G TI+
Sbjct: 134 -IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERT 192
Query: 205 QPDLTKLHQ----------LAMQQSHFPMTHGNTGFSGI--ESSSPEVKGYWAGLDASAQ 252
+ + L + F + I E + +G ++
Sbjct: 193 GVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMG 252
Query: 253 TTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG-STDRQVTITGSAASIS 311
S E+++P +G +IGR G I +I+ +G +I+ P +G S +R + G
Sbjct: 253 GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMGPPDRCQ 311
Query: 312 LAQYLIN--VRLSSETGGMG 329
A ++I+ + + E G G
Sbjct: 312 HAAHIISELILTAQERDGFG 331
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 77.0 bits (188), Expect = 2e-14
Identities = 80/328 (24%), Positives = 144/328 (43%), Gaps = 35/328 (10%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQICVV----MLESPPKGVTIPY 178
++ ++ D+ + ER IT+ G ++ IE +K++ ML + IP
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIP- 364
Query: 179 RPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSP 238
S+ IF+ G + P H +F + + F P
Sbjct: 365 -GLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPF----P 419
Query: 239 EVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS-- 296
Y + L IP +G IIG++GA I ++ + +GA IKIA P EG
Sbjct: 420 HHHSY-------PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDV 471
Query: 297 TDRQVTITGSAASISLAQYLINVRLSSE 324
++R V ITG + AQ I +L E
Sbjct: 472 SERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 545 VPRDQTPDENEEVI 558
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 77.0 bits (188), Expect = 2e-14
Identities = 52/173 (30%), Positives = 91/173 (52%), Gaps = 21/173 (12%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 71 AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120
+ I +K+ E I +MT + +P T+ +L+VP S G +IGKGG +
Sbjct: 95 VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
Query: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESP 170
K + E +GA VQ++ P N ER +T++G P+ + + V I + E P
Sbjct: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDP 204
Score = 60.8 bits (146), Expect = 2e-09
Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 313
E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ +R+VTITGS A+ A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 314 QYLINVRLSSETGGMGSS 331
QYLI+ R++ E G S+
Sbjct: 470 QYLISQRVTYEQGVRASN 487
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 17 RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72
+L++ G IIGK G +VK + E+SGA + +S+ N ER++T++G + KA
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 73 AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117
+ I+ K++ED SS + NS P + V+PA+ S G
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
Score = 47.8 bits (112), Expect = 1e-05
Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 92 AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149
AA + + VP + G+++GKGG + E +E TGA++Q++ G+ LP + R +TI
Sbjct: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
Query: 150 GIP 152
G P
Sbjct: 461 GSP 463
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 313
+L +PN G IIG+ GA + + + SGA ++++ EG +R VT++G + A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
Score = 33.5 bits (75), Expect = 0.27
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 313
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R + G+A +++
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 314 QYLI 317
I
Sbjct: 96 HSFI 99
Score = 29.6 bits (65), Expect = 3.9
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE 51
VG+I+GK G+++ + +E +GARI IS+
Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 74.7 bits (182), Expect = 1e-13
Identities = 81/342 (23%), Positives = 143/342 (41%), Gaps = 47/342 (13%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D +
Sbjct: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
Query: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139
++ + +++PA + G +IGKGG IK+++E G ++ + D
Sbjct: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
Query: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184
N + ++ + I G P + + + + ++ E G+ +P P+ S
Sbjct: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
Query: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------MQQSHFPMT 224
VI G+ IQ + Q D T ++A + +
Sbjct: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
Query: 225 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGRQGAKINEIRQM 282
G G G P +G G + E+T IP G +IGR G + I Q
Sbjct: 395 SGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
Query: 283 SGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 321
+GA ++I+ + + D + I GS I A+ LI ++
Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
Score = 69.7 bits (169), Expect = 3e-12
Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+
Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
Query: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126
S PP + +P +CG +IG+GG +K I +
Sbjct: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172
TGA V+++ + PN + I G PQ I+ KQ+ +E P P
Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
Query: 173 GVTIPYRPKP 182
G P+ P P
Sbjct: 513 GPMGPFNPGP 522
Score = 53.1 bits (126), Expect = 3e-07
Identities = 25/73 (34%), Positives = 47/73 (64%)
Query: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
+ E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+
Sbjct: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
Query: 315 YLINVRLSSETGG 327
+++ +S GG
Sbjct: 206 MMLDDIVSRGRGG 218
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Query: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138
+ ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
Query: 139 PNSTERAITIAGIPQSI 155
P ER++++ G P+S+
Sbjct: 188 P---ERSVSLTGAPESV 201
Score = 30.0 bits (66), Expect = 3.0
Identities = 18/71 (25%), Positives = 31/71 (43%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 316
++ +P +G +IGR G I +I+ +G +I+ ++ I G A +
Sbjct: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 317 INVRLSSETGG 327
IN L S G
Sbjct: 386 INDLLQSLRSG 396
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 502 VPRDQTPDENEEVI 515
Score = 68.9 bits (167), Expect = 6e-12
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 26/167 (15%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
Query: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
A I+ KL E + M T+S S + L +P
Sbjct: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
Query: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
Score = 56.6 bits (135), Expect = 3e-08
Identities = 70/319 (21%), Positives = 134/319 (42%), Gaps = 60/319 (18%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+
Sbjct: 252 SEACRMILEIMQKEADETKLAEE------IPLKILAHNGLVGRLIGKEGRNLKK------ 299
Query: 129 AQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
+ + T ITI+ + + + +P + +T+ + +S I
Sbjct: 300 ---------IEHETGTKITISSLQD-----------LSIYNPERTITVKGTVEACASAEI 339
Query: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK-GYWAGL 247
++ K + A + M NT S P + G +
Sbjct: 340 ------------------EIMKKLREAFEND---MLAVNTHSGYFSSLYPHHQFGPFPHH 378
Query: 248 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITG 305
+ + L IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG
Sbjct: 379 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITG 437
Query: 306 SAASISLAQYLINVRLSSE 324
+ AQ I +L E
Sbjct: 438 PPEAQFKAQGRIFGKLKEE 456
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 3e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
Query: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Query: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
Query: 184 SSP 186
P
Sbjct: 466 PGP 468
Score = 68.9 bits (167), Expect = 6e-12
Identities = 79/347 (22%), Positives = 141/347 (40%), Gaps = 45/347 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
Query: 142 TERAITIAGIPQSIIECVKQICVVMLE---------------SPPKGVTIPYRPKPSSSP 186
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
Query: 187 VIFAGGQAY-TIQGQYAIP---QPDLTKLHQLAMQQSHFP----------------MTHG 226
VI G+ IQ + +PD + Q + P + G
Sbjct: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
Query: 227 NTGFSGIES-SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGA 285
N G G +G W + +P G IIG+ G I I Q SGA
Sbjct: 350 NPGGPGPGGRGRGRGQGNW-NMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGA 408
Query: 286 QIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGGMG 329
+I++ + D + TI G+ I A+ LI ++ +G
Sbjct: 409 RIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 250 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 309
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
Query: 310 ISLAQYLIN 318
+ A+ L++
Sbjct: 157 VQSAKRLLD 165
Score = 47.4 bits (111), Expect = 2e-05
Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 51/269 (18%)
Query: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
Query: 152 PQSIIECVKQICVVMLE------------SPPKGVTIPYRPKPSSSPVIFAGGQAY-TIQ 198
P+S ++ K++ ++E P V P + VI GG+ +Q
Sbjct: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
Query: 199 GQYAI--------PQ-----------PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPE 239
+ + PQ D K+ Q ++ + GF + +
Sbjct: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQ--AKEMVLELIRDQGGFREVRNEYGS 270
Query: 240 VKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST-D 298
G G+D + IP +G +IGR G I +I+ +G +I+ P +G+T +
Sbjct: 271 RIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGTTPE 320
Query: 299 RQVTITGSAASISLAQYLINVRLSSETGG 327
R ITG A +I L S G
Sbjct: 321 RIAQITGPPDRCQHAAEIITDLLRSVQAG 349
Score = 35.8 bits (81), Expect = 0.054
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
Query: 79 L 79
+
Sbjct: 447 I 447
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 72.4 bits (176), Expect = 5e-13
Identities = 74/319 (23%), Positives = 142/319 (44%), Gaps = 41/319 (12%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
++ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA----------- 356
Query: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAG 246
A ++Q + IP +L + S P S + ++P Y +
Sbjct: 357 -------AMSLQ-SHLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP----YSSF 399
Query: 247 LDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
+ A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V ITG
Sbjct: 400 MQAPEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
Query: 306 SAASISLAQYLINVRLSSE 324
+ AQ I +L E
Sbjct: 459 PPEAQFKAQGRIYGKLKEE 477
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 523 VPRDQTPDENDQVI 536
Score = 30.4 bits (67), Expect = 2.3
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 198 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 250
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Query: 251 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 307
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Query: 308 ASISLAQYLI 317
S A +I
Sbjct: 251 EGCSSACKMI 260
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 70.9 bits (172), Expect = 2e-12
Identities = 81/321 (25%), Positives = 146/321 (45%), Gaps = 49/321 (15%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
Query: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSS 185
++ ++ ++ + ER IT+ G ++ + ++I + ES +
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES-------------YEN 353
Query: 186 PVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWA 245
+ QA+ I G L+ L + FP T +G S P
Sbjct: 354 DIASMNLQAHLIPG---------LNLNALGL----FPPT---SGMPPPTSGPPSAMTPPY 397
Query: 246 GLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDRQVTI 303
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R V I
Sbjct: 398 PQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVRMVII 456
Query: 304 TGSAASISLAQYLINVRLSSE 324
TG + AQ I ++ E
Sbjct: 457 TGPPEAQFKAQGRIYGKIKEE 477
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
Query: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
Query: 130 QVQVAGDMLPNSTERAI 146
+V V D P+ ++ +
Sbjct: 520 EVVVPRDQTPDENDQVV 536
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
Query: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
A I+ K+ E + + +S+A PP +
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
Query: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
Query: 151 IPQS 154
P++
Sbjct: 320 PPEA 323
Score = 49.7 bits (117), Expect = 4e-06
Identities = 59/257 (22%), Positives = 110/257 (42%), Gaps = 38/257 (14%)
Query: 77 DKLEEDISSSMTNSTAASRPP------VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
+++ + +++ N T ++R V L+++ + G LIGK G +K++ + T +
Sbjct: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
Query: 131 VQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
+ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA------------- 217
Query: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLD 248
A ++Q + IP +L + S P S + ++P Y + +
Sbjct: 218 -----AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP----YSSFMQ 262
Query: 249 ASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSA 307
A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V ITG
Sbjct: 263 APEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPP 321
Query: 308 ASISLAQYLINVRLSSE 324
+ AQ I +L E
Sbjct: 322 EAQFKAQGRIYGKLKEE 338
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 68.2 bits (165), Expect = 1e-11
Identities = 80/303 (26%), Positives = 131/303 (43%), Gaps = 38/303 (12%)
Query: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
Query: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAY 195
E++ ++IAG P + +I V+M E P G+ P P P+S P I Q Y
Sbjct: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNS-PSIQHISQTY 235
Query: 196 TIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTS 255
I + + M + + S ++ + + + AG ASA S
Sbjct: 236 NISVSFK---------QRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVS 286
Query: 256 HELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA-Q 314
+L I ++GR G+ I I Q +GAQI +P V + G+ S+ LA Q
Sbjct: 287 TQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
Query: 315 YLI 317
YL+
Sbjct: 347 YLM 349
Score = 32.0 bits (71), Expect = 0.78
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 9e-08
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 312
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 313 AQYLINVRLSSE 324
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 316
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 317 INVRLSSET 325
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 9e-08
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 312
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 313 AQYLINVRLSSE 324
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 316
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 317 INVRLSSET 325
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,606,975
Number of Sequences: 37866
Number of extensions: 574809
Number of successful extensions: 1400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1015
Number of HSP's gapped (non-prelim): 257
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.