BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148528975 LON peptidase N-terminal domain and ring finger 2 [Homo sapiens] (754 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 1522 0.0 gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 563 e-160 gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 498 e-141 gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 457 e-128 gi|239747122 PREDICTED: hypothetical protein XP_002343916 [Homo ... 218 1e-56 gi|239746558 PREDICTED: hypothetical protein XP_002343788 [Homo ... 218 1e-56 gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 56 1e-07 gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 54 5e-07 gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 52 2e-06 gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 52 2e-06 gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 52 2e-06 gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 52 2e-06 gi|31377566 ring finger protein 168 [Homo sapiens] 52 2e-06 gi|37595555 ring finger protein 125 [Homo sapiens] 52 2e-06 gi|54792146 tripartite motif-containing 47 [Homo sapiens] 52 3e-06 gi|210147600 tripartite motif-containing 64 [Homo sapiens] 50 8e-06 gi|7706091 bifunctional apoptosis regulator [Homo sapiens] 50 8e-06 gi|239755486 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|239755484 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|239750044 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|239750042 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|239744355 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|239744353 PREDICTED: tripartite motif-containing protein 64C-... 50 1e-05 gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 50 1e-05 gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 50 1e-05 gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 50 1e-05 gi|109240538 polycomb group ring finger 1 [Homo sapiens] 49 1e-05 gi|8923898 zinc finger protein 313 [Homo sapiens] 49 2e-05 gi|22749269 ring finger protein 129 [Homo sapiens] 49 2e-05 gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 49 2e-05 >gi|148528975 LON peptidase N-terminal domain and ring finger 2 [Homo sapiens] Length = 754 Score = 1522 bits (3941), Expect = 0.0 Identities = 754/754 (100%), Positives = 754/754 (100%) Query: 1 MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGL 60 MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGL Sbjct: 1 MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGL 60 Query: 61 CLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAVGLRDRPLSAENPGG 120 CLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAVGLRDRPLSAENPGG Sbjct: 61 CLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAVGLRDRPLSAENPGG 120 Query: 121 EPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVN 180 EPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVN Sbjct: 121 EPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVN 180 Query: 181 VVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAEL 240 VVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAEL Sbjct: 181 VVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAEL 240 Query: 241 YLTMKNYEQALQDASAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNS 300 YLTMKNYEQALQDASAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNS Sbjct: 241 YLTMKNYEQALQDASAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNS 300 Query: 301 VKKEAQKVMCEVLFSATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEK 360 VKKEAQKVMCEVLFSATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEK Sbjct: 301 VKKEAQKVMCEVLFSATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEK 360 Query: 361 SDMLGNTNSSVLYFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIP 420 SDMLGNTNSSVLYFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIP Sbjct: 361 SDMLGNTNSSVLYFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIP 420 Query: 421 KKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHA 480 KKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHA Sbjct: 421 KKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHA 480 Query: 481 PHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPI 540 PHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPI Sbjct: 481 PHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPI 540 Query: 541 FVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVR 600 FVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVR Sbjct: 541 FVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVR 600 Query: 601 TFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQS 660 TFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQS Sbjct: 601 TFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQS 660 Query: 661 VSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMT 720 VSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMT Sbjct: 661 VSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMT 720 Query: 721 SLKERLLAIRRILVIITRKMNSRQELANARERNN 754 SLKERLLAIRRILVIITRKMNSRQELANARERNN Sbjct: 721 SLKERLLAIRRILVIITRKMNSRQELANARERNN 754 >gi|73747840 LON peptidase N-terminal domain and ring finger 3 isoform 1 [Homo sapiens] Length = 759 Score = 563 bits (1452), Expect = e-160 Identities = 318/730 (43%), Positives = 428/730 (58%), Gaps = 71/730 (9%) Query: 52 GLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAV----G 107 G + P+ + L DALA GR+ EAL +R + L E+LE+L L V Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120 Query: 108 LRDRPLSAENPGGEPEAPGEGGPAPEPRAPR--DLLGCPRCRRLLHKPVTLPCGLTVCKR 165 L P + A E G A A D C +C L PV+L CG T CK Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180 Query: 166 CVEPGPAR-------------------------------PQVRRVNVVLSGLLEKCFPAE 194 C+E G A P RVNVVLSGLL K FP Sbjct: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240 Query: 195 CRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDA 254 R +L + L R++Q EAALL+ ++A++LAP+D+ L R+++Y T++++E AL DA Sbjct: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300 Query: 255 SAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLF 314 AC+ P+ K H KAQAL+ LG+ +E L+EFLYC++L+ + + EAQ+ E+ Sbjct: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL-- 358 Query: 315 SATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYF 374 + +S ++ + G S M+ + +G ++ E+ + T+ Sbjct: 359 -------PHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASS 411 Query: 375 ILGLHFEEDKK--ALESILPTA-PSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPN 431 G E+ +K +ES T P+ K+ P D D P L+ P Sbjct: 412 KTGKCQEKKRKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLA------------- 458 Query: 432 SETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLS 491 S D +D ECALCMRL +EPVTTPCGHTFCLKCLERCLDH CPLCKD LS Sbjct: 459 ---------SFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLS 509 Query: 492 ELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVP 551 + LASR ++ V+ EELI ++LP+EL +R+++Y+EEM ELSNL ++VPIFVC MA+PTVP Sbjct: 510 QCLASRKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVP 569 Query: 552 CPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDA 611 CPLH+FEP YRLMIRRC+ETGT++FGMCL G +EYGC+LEI++V+ F DG SVVD+ Sbjct: 570 CPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDS 629 Query: 612 IGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRM 671 IG RFRVL RDGYNTADIEY+ED+KV+G + EL LH+ V+QQ+ WF SL+ + Sbjct: 630 IGKRRFRVLHQSQRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSL 689 Query: 672 KEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRR 731 K +IL+HFG MP+++ +PQ NP+GPAW WW+LAVLPLE +AQL L M SLK+RL IRR Sbjct: 690 KNRILNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRR 749 Query: 732 ILVIITRKMN 741 +L I+R N Sbjct: 750 VLAFISRNQN 759 >gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo sapiens] Length = 773 Score = 498 bits (1283), Expect = e-141 Identities = 305/739 (41%), Positives = 409/739 (55%), Gaps = 79/739 (10%) Query: 60 LCLRLGDALARAGRLPEALGAFRGAARLGA-LRPEELEELAGGLVRAVGLRDRPLSAENP 118 L LR G+ LA G L AL AF A R GA RPE L G LV + R Sbjct: 50 LLLRRGELLALGGHLKGALEAFAAALRRGAPARPECL----GALVDCLVFNYRLRHGLGW 105 Query: 119 GGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVE---------- 168 P A +GG LL C CR L +PVT+PCG + C+RC+ Sbjct: 106 SAAPVAGADGGAG-------GLLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLC 158 Query: 169 --------------------PGPARPQVR----RVNVVLSGLLEKCFPAECRLRRLAGQA 204 P P + R +VVL+ L EK FP + R AG+ Sbjct: 159 RDRLPPATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRL 218 Query: 205 RSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDASAACQNEPLL 264 L Q + AL +AL P D + + RAE Y ++ ++ A++D +A P Sbjct: 219 GELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVLFQLPDW 278 Query: 265 IKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENL 324 + + K + L G + L+ FL CLAL+ + K + QK++C++L N+ E L Sbjct: 279 PEVYFRKGKVLCDAGFLGDALQLFLQCLALDEDFAPAKLQVQKILCDLLLPE--NLKEGL 336 Query: 325 TSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDK 384 S S L + + +++EE + +E S ++S+ + S + L+ + Sbjct: 337 KESSWSSLPCTKNRPFDFHSVMEESQS-LNEPSPKQSEEIPEVTSEPVKG--SLNRAQSA 393 Query: 385 KALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEES------Q 438 +++ S A LKR + V + G + K+ LSL E+ Q Sbjct: 394 QSINSTEMPAREDCLKRVSSEPVLSVQE---KGVLLKRKLSLLEQDVIVNEDGRNKLKKQ 450 Query: 439 GLS------------------LDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHA 480 G + +DV+DFEC+LCMRL FEPVTTPCGH+FC CLERCLDHA Sbjct: 451 GETPNEVCMFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHA 510 Query: 481 PHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPI 540 P+CPLCK+ L E LA R + +T L EELI +YLPDELS+RK+IYDEE +ELS+LT++VPI Sbjct: 511 PYCPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPI 570 Query: 541 FVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVR 600 FVC MA+PTVPCPLHVFEPRYRLMIRR ++TGTK+FGMC+S ++YGCML+I++V Sbjct: 571 FVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVH 630 Query: 601 TFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEG-PEYEELAALHDSVHQQ 659 PDG SVVD +G RFRVL +DGY TADIEYLED KVE E + L LHD V+ Q Sbjct: 631 FLPDGRSVVDTVGGKRFRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHDLVYSQ 690 Query: 660 SVSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGM 719 + SWF +L+DR + QIL HFG MP+RE Q+ P+GPAW WW+LAVLP++ + QL++L M Sbjct: 691 ACSWFQNLRDRFRSQILQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQLSVLSM 750 Query: 720 TSLKERLLAIRRILVIITR 738 SLKERL I+ IL +R Sbjct: 751 KSLKERLTKIQHILTYFSR 769 >gi|37622896 LON peptidase N-terminal domain and ring finger 3 isoform 2 [Homo sapiens] Length = 718 Score = 457 bits (1177), Expect = e-128 Identities = 289/711 (40%), Positives = 381/711 (53%), Gaps = 74/711 (10%) Query: 52 GLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAV----G 107 G + P+ + L DALA GR+ EAL +R + L E+LE+L L V Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120 Query: 108 LRDRPLSAENPGGEPEAPGEGGPAPEPRAPR--DLLGCPRCRRLLHKPVTLPCGLTVCKR 165 L P + A E G A A D C +C L PV+L CG T CK Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180 Query: 166 CVEPGPARPQ-VRRVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQAL 224 C+E G A + V LS L+ G+AR +R Q LR + L Sbjct: 181 CLERGRAADRRCALCGVKLSALMVA-----------TGRARGARRAGQQPPPPLRVNVVL 229 Query: 225 -----ELAPDDNSLLLLRAE---LYLTMKNYEQAL---QDASAACQNEPLLIKGHQVKAQ 273 +L P LR E LY + E AL +A N+ LL ++Q Sbjct: 230 SGLLGKLFPGPARASQLRHEGNRLYRE-RQVEAALLKYNEAVKLAPNDHLLYSN---RSQ 285 Query: 274 ALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENLTSSIQSRLK 333 L + L + L P K + C +S ++ + Sbjct: 286 IYFTLESHENALHDAEIACKLRPM--GFKDNLELPHC--------------SSQEEAAAR 329 Query: 334 AQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDKK--ALESIL 391 G S M+ + +G ++ E+ + T+ G E+ +K +ES Sbjct: 330 GDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKKRKHCQIESQE 389 Query: 392 PTA-PSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECA 450 T P+ K+ P D D P L+ P S D +D ECA Sbjct: 390 ETGMPNKASKQDPPTDQGDKPALSLPLA----------------------SFDASDLECA 427 Query: 451 LCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEELIF 510 LCMRL +EPVTTPCGHTFCLKCLERCLDH CPLCKD LS+ LASR ++ V+ EELI Sbjct: 428 LCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIA 487 Query: 511 RYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVPCPLHVFEPRYRLMIRRCME 570 ++LP+EL +R+++Y+EEM ELSNL ++VPIFVC MA+PTVPCPLH+FEP YRLMIRRC+E Sbjct: 488 KFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIE 547 Query: 571 TGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDAIGISRFRVLSHRHRDGYNT 630 TGT++FGMCL G +EYGC+LEI++V+ F DG SVVD+IG RFRVL RDGYNT Sbjct: 548 TGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNT 607 Query: 631 ADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRMKEQILSHFGVMPDREPEPQ 690 ADIEY+ED+KV+G + EL LH+ V+QQ+ WF SL+ +K +IL+HFG MP+++ +PQ Sbjct: 608 ADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQ 667 Query: 691 SNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRRILVIITRKMN 741 NP+GPAW WW+LAVLPLE +AQL L M SLK+RL IRR+L I+R N Sbjct: 668 MNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718 >gi|239747122 PREDICTED: hypothetical protein XP_002343916 [Homo sapiens] Length = 598 Score = 218 bits (556), Expect = 1e-56 Identities = 133/222 (59%), Positives = 140/222 (63%), Gaps = 45/222 (20%) Query: 1 MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGL 60 +S EPVPPPP QCPGCD EPIAQRLEEGDEAFR +Y+ AA LFRS LA LAQPDRG Sbjct: 49 ISTEPVPPPP--QCPGCDCGEPIAQRLEEGDEAFRQSEYQKAAGLFRSTLARLAQPDRGQ 106 Query: 61 CLRLGDALARAGRLPEALGAFRGAARLGALRPE---ELEELAGGLVRAVGLRDRPLSAEN 117 CLRLG+ALARA RLP ALGAF A RL ALRPE EL ELAGGLV GLR+RPL Sbjct: 107 CLRLGNALARADRLPVALGAFCVALRLEALRPEELGELAELAGGLV-CPGLRERPLFTGK 165 Query: 118 PGGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVR 177 PGGE EAP G G RPQ Sbjct: 166 PGGELEAPALRG---------------------------------------AGAERPQAL 186 Query: 178 RVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLR 219 RVNVVLS LE+CFPA+C L RL GQARSLQRQQQPEAALLR Sbjct: 187 RVNVVLSRKLERCFPAKCPLLRLEGQARSLQRQQQPEAALLR 228 >gi|239746558 PREDICTED: hypothetical protein XP_002343788 [Homo sapiens] Length = 616 Score = 218 bits (556), Expect = 1e-56 Identities = 133/222 (59%), Positives = 140/222 (63%), Gaps = 45/222 (20%) Query: 1 MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGL 60 +S EPVPPPP QCPGCD EPIAQRLEEGDEAFR +Y+ AA LFRS LA LAQPDRG Sbjct: 67 ISTEPVPPPP--QCPGCDCGEPIAQRLEEGDEAFRQSEYQKAAGLFRSTLARLAQPDRGQ 124 Query: 61 CLRLGDALARAGRLPEALGAFRGAARLGALRPE---ELEELAGGLVRAVGLRDRPLSAEN 117 CLRLG+ALARA RLP ALGAF A RL ALRPE EL ELAGGLV GLR+RPL Sbjct: 125 CLRLGNALARADRLPVALGAFCVALRLEALRPEELGELAELAGGLV-CPGLRERPLFTGK 183 Query: 118 PGGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVR 177 PGGE EAP G G RPQ Sbjct: 184 PGGELEAPALRG---------------------------------------AGAERPQAL 204 Query: 178 RVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLR 219 RVNVVLS LE+CFPA+C L RL GQARSLQRQQQPEAALLR Sbjct: 205 RVNVVLSRKLERCFPAKCPLLRLEGQARSLQRQQQPEAALLR 246 >gi|24025688 ligand of numb-protein X 2 [Homo sapiens] Length = 690 Score = 56.2 bits (134), Expect = 1e-07 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Query: 446 DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLA 505 D C +C++ L +P+ TPCGHTFC KCL L CPL + +L L ++ ++L Sbjct: 47 DLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKS---SILV 103 Query: 506 EELIFRYL 513 +L+ + L Sbjct: 104 HKLLDKLL 111 >gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] Length = 493 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Query: 426 LQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERC--LDHAPHC 483 ++RSP+ S+ ++ CA+C + VT CGH FC C+ RC + +P C Sbjct: 1 MERSPDVSPGPSRSFKEELL---CAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTC 57 Query: 484 PLCKDKLSELLASRNFNITVLAEELI 509 P+CKD+ S N + L E+L+ Sbjct: 58 PVCKDRASPADLRTNHTLNNLVEKLL 83 Score = 31.6 bits (70), Expect = 2.8 Identities = 53/198 (26%), Positives = 74/198 (37%), Gaps = 46/198 (23%) Query: 130 PAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVE--------------PGPARPQ 175 P P +LL C C VTL CG C+ CV A P Sbjct: 9 PGPSRSFKEELL-CAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPA 67 Query: 176 VRRVNVVLSGLLEKC--------------FPAECRLRRLAGQARSLQRQQQPEAALLRCD 221 R N L+ L+EK F CRL R GQ SL + E C Sbjct: 68 DLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHR--GQL-SLFCLEDKELLCCSCQ 124 Query: 222 -----QALELAPDDNSLLLLRAELYLTMKNYEQALQDASAAC----QNEPLLIKGHQVKA 272 Q + P ++ RA+ +N E AL++ + A ++ + K +QV+A Sbjct: 125 ADPRHQGHRVQPVKDTAHDFRAK----CRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA 180 Query: 273 QALSGLGRSK-EVLKEFL 289 L G R + + L+EFL Sbjct: 181 AWLEGRIRQEFDKLREFL 198 >gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] Length = 1884 Score = 52.4 bits (124), Expect = 2e-06 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 448 ECALCMRLLFEPVTTPCGHTFCLKCLERCLDH---APHCPLCKDKLSELLASRNFNITVL 504 EC +C+ L+ EPV+T C H FC C+ + L+ CPLCK+ +++ + + L Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82 Query: 505 AEELI 509 EEL+ Sbjct: 83 VEELL 87 Score = 31.2 bits (69), Expect = 3.7 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 15/73 (20%) Query: 136 APRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAEC 195 A + +L CP C L+ +PV+ C CK C +L L +K P++C Sbjct: 17 AMQKILECPICLELIKEPVSTKCDHIFCKFC---------------MLKLLNQKKGPSQC 61 Query: 196 RLRRLAGQARSLQ 208 L + RSLQ Sbjct: 62 PLCKNDITKRSLQ 74 >gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] Length = 699 Score = 52.4 bits (124), Expect = 2e-06 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 448 ECALCMRLLFEPVTTPCGHTFCLKCLERCLDH---APHCPLCKDKLSELLASRNFNITVL 504 EC +C+ L+ EPV+T C H FC C+ + L+ CPLCK+ +++ + + L Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82 Query: 505 AEELI 509 EEL+ Sbjct: 83 VEELL 87 Score = 32.0 bits (71), Expect = 2.2 Identities = 83/376 (22%), Positives = 138/376 (36%), Gaps = 89/376 (23%) Query: 136 APRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAEC 195 A + +L CP C L+ +PV+ C CK C +L L +K P++C Sbjct: 17 AMQKILECPICLELIKEPVSTKCDHIFCKFC---------------MLKLLNQKKGPSQC 61 Query: 196 RLRRLAGQARSLQ---RQQQPEAALLR------CDQALELA----------------PDD 230 L + RSLQ R Q LL+ D LE A D+ Sbjct: 62 PLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDE 121 Query: 231 NSLLLL-----RAELYLTMKNYEQALQDASAACQNEPL-----LIKGHQVKAQALS---- 276 S++ RA+ L + +LQ+ S + Q L L +++ Q S Sbjct: 122 VSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIE 181 Query: 277 -GLGRSKEVLKEFLYCLALNPECNSVKKE----------AQKVMCEVLFSATANV--HEN 323 G S++ + + YC + E + + A+K CE + N H+ Sbjct: 182 LGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQP 241 Query: 324 LTSSIQSRLKAQGHSHMNAQALLEEGDAGS---SENS--------SEKSDMLGNTNSSVL 372 + + + K H +G+A S SE S S +SD+L + Sbjct: 242 SNNDLNTTEKRAAERHPEKY----QGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTM 297 Query: 373 YFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDL----NAPGKIPKKDLSLQR 428 L + +++ LE++L S +P + D+ L N +K L+ Q+ Sbjct: 298 QHNL-IKLQQEMAELEAVLEQHGSQP-SNSYPSIISDSSALEDLRNPEQSTSEKVLTSQK 355 Query: 429 SPNSE-TEESQGLSLD 443 S ++ +GLS D Sbjct: 356 SSEYPISQNPEGLSAD 371 >gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] Length = 759 Score = 52.4 bits (124), Expect = 2e-06 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 448 ECALCMRLLFEPVTTPCGHTFCLKCLERCLDH---APHCPLCKDKLSELLASRNFNITVL 504 EC +C+ L+ EPV+T C H FC C+ + L+ CPLCK+ +++ + + L Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82 Query: 505 AEELI 509 EEL+ Sbjct: 83 VEELL 87 Score = 32.0 bits (71), Expect = 2.2 Identities = 83/376 (22%), Positives = 138/376 (36%), Gaps = 89/376 (23%) Query: 136 APRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAEC 195 A + +L CP C L+ +PV+ C CK C +L L +K P++C Sbjct: 17 AMQKILECPICLELIKEPVSTKCDHIFCKFC---------------MLKLLNQKKGPSQC 61 Query: 196 RLRRLAGQARSLQ---RQQQPEAALLR------CDQALELA----------------PDD 230 L + RSLQ R Q LL+ D LE A D+ Sbjct: 62 PLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDE 121 Query: 231 NSLLLL-----RAELYLTMKNYEQALQDASAACQNEPL-----LIKGHQVKAQALS---- 276 S++ RA+ L + +LQ+ S + Q L L +++ Q S Sbjct: 122 VSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIE 181 Query: 277 -GLGRSKEVLKEFLYCLALNPECNSVKKE----------AQKVMCEVLFSATANV--HEN 323 G S++ + + YC + E + + A+K CE + N H+ Sbjct: 182 LGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQP 241 Query: 324 LTSSIQSRLKAQGHSHMNAQALLEEGDAGS---SENS--------SEKSDMLGNTNSSVL 372 + + + K H +G+A S SE S S +SD+L + Sbjct: 242 SNNDLNTTEKRAAERHPEKY----QGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTM 297 Query: 373 YFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDL----NAPGKIPKKDLSLQR 428 L + +++ LE++L S +P + D+ L N +K L+ Q+ Sbjct: 298 QHNL-IKLQQEMAELEAVLEQHGSQP-SNSYPSIISDSSALEDLRNPEQSTSEKVLTSQK 355 Query: 429 SPNSE-TEESQGLSLD 443 S ++ +GLS D Sbjct: 356 SSEYPISQNPEGLSAD 371 >gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] Length = 1863 Score = 52.4 bits (124), Expect = 2e-06 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 448 ECALCMRLLFEPVTTPCGHTFCLKCLERCLDH---APHCPLCKDKLSELLASRNFNITVL 504 EC +C+ L+ EPV+T C H FC C+ + L+ CPLCK+ +++ + + L Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82 Query: 505 AEELI 509 EEL+ Sbjct: 83 VEELL 87 Score = 31.2 bits (69), Expect = 3.7 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 15/73 (20%) Query: 136 APRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAEC 195 A + +L CP C L+ +PV+ C CK C +L L +K P++C Sbjct: 17 AMQKILECPICLELIKEPVSTKCDHIFCKFC---------------MLKLLNQKKGPSQC 61 Query: 196 RLRRLAGQARSLQ 208 L + RSLQ Sbjct: 62 PLCKNDITKRSLQ 74 >gi|31377566 ring finger protein 168 [Homo sapiens] Length = 571 Score = 52.4 bits (124), Expect = 2e-06 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Query: 444 VTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAP-HCPLCKDKLSELL---ASRNF 499 +++ +C +CM +L EPVT PC HT C C + ++ A CP C+ ++S RN Sbjct: 11 LSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNS 70 Query: 500 NITVLAEELIFRYLPDELSDRKRIYDEEMSELSN 533 + V +I ++ P E + R +E E+++ Sbjct: 71 LVNVELWTIIQKHYPREC--KLRASGQESEEVAD 102 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 20/91 (21%) Query: 143 CPRCRRLLHKPVTLPCGLTVCKRCVEPGPAR-----PQVRR---------------VNVV 182 C C +L +PVTLPC T+CK C + + P RR VNV Sbjct: 16 CGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVE 75 Query: 183 LSGLLEKCFPAECRLRRLAGQARSLQRQQQP 213 L +++K +P EC+LR ++ + QP Sbjct: 76 LWTIIQKHYPRECKLRASGQESEEVADDYQP 106 >gi|37595555 ring finger protein 125 [Homo sapiens] Length = 232 Score = 52.4 bits (124), Expect = 2e-06 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 11/75 (14%) Query: 414 NAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCL 473 +AP + L +R P L VT F+CA+C+ +L +PV T CGH FC C+ Sbjct: 12 SAPASATARALERRRDPE----------LPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCI 61 Query: 474 ERCL-DHAPHCPLCK 487 L ++ CP C+ Sbjct: 62 ATSLKNNKWTCPYCR 76 Score = 33.1 bits (74), Expect = 0.98 Identities = 12/35 (34%), Positives = 17/35 (48%) Query: 133 EPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCV 167 +P P C C +LH+PV CG C+ C+ Sbjct: 27 DPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCI 61 >gi|54792146 tripartite motif-containing 47 [Homo sapiens] Length = 638 Score = 51.6 bits (122), Expect = 3e-06 Identities = 25/62 (40%), Positives = 30/62 (48%), Gaps = 11/62 (17%) Query: 447 FECALCMRLLFEPVTTPCGHTFCLKCLERCLDH-----------APHCPLCKDKLSELLA 495 F C +C+ L EPVT PCGH FCL CL H A CPLC++ + L Sbjct: 7 FSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQ 66 Query: 496 SR 497 R Sbjct: 67 LR 68 Score = 33.9 bits (76), Expect = 0.57 Identities = 13/25 (52%), Positives = 15/25 (60%) Query: 143 CPRCRRLLHKPVTLPCGLTVCKRCV 167 CP C L +PVTLPCG C C+ Sbjct: 9 CPICLEPLREPVTLPCGHNFCLACL 33 >gi|210147600 tripartite motif-containing 64 [Homo sapiens] Length = 449 Score = 50.1 bits (118), Expect = 8e-06 Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVT CGH+FC CL C + AP CP C+ K+SE Sbjct: 2 DSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V+ ++L Sbjct: 61 ---KPNFNTNVVLKKL 73 >gi|7706091 bifunctional apoptosis regulator [Homo sapiens] Length = 450 Score = 50.1 bits (118), Expect = 8e-06 Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 14/131 (10%) Query: 413 LNAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKC 472 + P K + L+R E +S G + V++F C C +L P T CGH+FC C Sbjct: 1 MEEPQKSYVNTMDLERD---EPLKSTGPQISVSEFSCHCCYDILVNPTTLNCGHSFCRHC 57 Query: 473 LER--CLDHAPHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSE 530 L CP C++K +++L + I + PD + R+ E++ + Sbjct: 58 LALWWASSKKTECPECREKWEGFP-----KVSILLRDAIEKLFPDAI----RLRFEDIQQ 108 Query: 531 LSNLTRDVPIF 541 +++ + + F Sbjct: 109 NNDIVQSLAAF 119 Score = 33.9 bits (76), Expect = 0.57 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 13/69 (18%) Query: 143 CPRCRRLLHKPVTLPCGLTVCKRCVEPGPAR------PQVR-------RVNVVLSGLLEK 189 C C +L P TL CG + C+ C+ A P+ R +V+++L +EK Sbjct: 34 CHCCYDILVNPTTLNCGHSFCRHCLALWWASSKKTECPECREKWEGFPKVSILLRDAIEK 93 Query: 190 CFPAECRLR 198 FP RLR Sbjct: 94 LFPDAIRLR 102 >gi|239755486 PREDICTED: tripartite motif-containing protein 64C-like isoform 2 [Homo sapiens] Length = 447 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|239755484 PREDICTED: tripartite motif-containing protein 64C-like isoform 1 [Homo sapiens] Length = 450 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|239750044 PREDICTED: tripartite motif-containing protein 64C-like isoform 2 [Homo sapiens] Length = 447 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|239750042 PREDICTED: tripartite motif-containing protein 64C-like isoform 1 [Homo sapiens] Length = 450 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|239744355 PREDICTED: tripartite motif-containing protein 64C-like isoform 1 [Homo sapiens] Length = 447 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|239744353 PREDICTED: tripartite motif-containing protein 64C-like isoform 2 [Homo sapiens] Length = 450 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 436 ESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLD--HAP-HCPLCKDKLSE 492 +S L + + C +C+ +PVTT C H+FC CL C + AP CPLC+ K+SE Sbjct: 2 DSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60 Query: 493 LLASRNFNITVLAEEL 508 NFN V ++L Sbjct: 61 ---KPNFNTNVALKKL 73 >gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] Length = 1066 Score = 49.7 bits (117), Expect = 1e-05 Identities = 21/47 (44%), Positives = 30/47 (63%), Gaps = 1/47 (2%) Query: 446 DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPL-CKDKLS 491 D +CALC ++L +P+TTPCGH FC C+ + CP C+ +LS Sbjct: 15 DLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLS 61 Score = 34.3 bits (77), Expect = 0.44 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 20/98 (20%) Query: 141 LGCPRCRRLLHKPVTLPCGLTVCKRCVEPG-------PARPQVRRVNVVLSGLLEKCFPA 193 L C C ++L P+T PCG C CV P PAR + R L+ +L P Sbjct: 16 LKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKELNHVL----PL 71 Query: 194 ECRLRRL--------AGQARSLQRQQQPEAALLRCDQA 223 + + +L G R ++ QQ PE L RCD A Sbjct: 72 KRLILKLDIKCAYATRGCGRVVKLQQLPE-HLERCDFA 108 >gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapiens] Length = 481 Score = 49.7 bits (117), Expect = 1e-05 Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 7/50 (14%) Query: 446 DFECALCMRLLFEPVTTPCGHTFCLKCLERC-------LDHAPHCPLCKD 488 + C +C L EPVT CGH FC CL R L+ +P CPLCK+ Sbjct: 13 EVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKE 62 Score = 35.4 bits (80), Expect = 0.20 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%) Query: 139 DLLGCPRCRRLLHKPVTLPCGLTVCKRCVE-----PGP 171 D + CP C+ L +PVT+ CG C+ C+ PGP Sbjct: 12 DEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGP 49 >gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapiens] Length = 395 Score = 49.7 bits (117), Expect = 1e-05 Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 7/50 (14%) Query: 446 DFECALCMRLLFEPVTTPCGHTFCLKCLERC-------LDHAPHCPLCKD 488 + C +C L EPVT CGH FC CL R L+ +P CPLCK+ Sbjct: 13 EVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKE 62 Score = 35.4 bits (80), Expect = 0.20 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%) Query: 139 DLLGCPRCRRLLHKPVTLPCGLTVCKRCVE-----PGP 171 D + CP C+ L +PVT+ CG C+ C+ PGP Sbjct: 12 DEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGP 49 >gi|109240538 polycomb group ring finger 1 [Homo sapiens] Length = 259 Score = 49.3 bits (116), Expect = 1e-05 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 449 CALCMRLLFEPVT-TPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEE 507 C LC + T T C HTFC C+ + L + +CP+C K+ E N + + ++ Sbjct: 47 CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQD 106 Query: 508 LIFRYLPD-ELSDRKRI 523 ++++ +P + S+ KRI Sbjct: 107 IVYKLVPGLQDSEEKRI 123 >gi|8923898 zinc finger protein 313 [Homo sapiens] Length = 228 Score = 48.9 bits (115), Expect = 2e-05 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Query: 447 FECALCMRLLFEPVTTPCGHTFCLKCLERCL-DHAPHCPLCKDKLS 491 F C +C+ + +PV PCGH FC CL+ CL P C +C+ L+ Sbjct: 27 FTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALA 72 Score = 35.8 bits (81), Expect = 0.15 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 3/38 (7%) Query: 134 PRAPRDLLG---CPRCRRLLHKPVTLPCGLTVCKRCVE 168 P A D LG CP C + KPV +PCG C C++ Sbjct: 17 PAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQ 54 >gi|22749269 ring finger protein 129 [Homo sapiens] Length = 471 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 11/110 (10%) Query: 449 CALCMRLLFEPVTTPCGHTFCLKCLE---RCLDHAPHCPLCKDKLSELLASRNFNITVLA 505 C +C+ L +PVT CGH FC CL + LD CP+C+ RN + L Sbjct: 16 CPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRNPQLRNLT 75 Query: 506 EELIFRYLPDELSDRKRIYDEEMSELSN------LTRDVPIFVCAMAFPT 549 E I + L S RKR + M E N +D+ I +F T Sbjct: 76 E--IAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFST 123 Score = 30.8 bits (68), Expect = 4.8 Identities = 11/25 (44%), Positives = 14/25 (56%) Query: 143 CPRCRRLLHKPVTLPCGLTVCKRCV 167 CP C L PVT+ CG C+ C+ Sbjct: 16 CPICLEYLKDPVTINCGHNFCRSCL 40 >gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo sapiens] Length = 731 Score = 48.5 bits (114), Expect = 2e-05 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 446 DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCK---DKLSELLASRNFNIT 502 DF C +C ++ E T CGH+FC KC+ + L+ CP C D + L + N Sbjct: 133 DFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNEL 192 Query: 503 VLAEELIF 510 +L ++ F Sbjct: 193 ILKQKQRF 200 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,856,887 Number of Sequences: 37866 Number of extensions: 1731685 Number of successful extensions: 14178 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 280 Number of HSP's successfully gapped in prelim test: 214 Number of HSP's that attempted gapping in prelim test: 12862 Number of HSP's gapped (non-prelim): 1390 length of query: 754 length of database: 18,247,518 effective HSP length: 110 effective length of query: 644 effective length of database: 14,082,258 effective search space: 9068974152 effective search space used: 9068974152 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.