Guide to the Human Genome
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Name: PTCHD1 Sequence: fasta or formatted (888aa) NCBI GI: 148271104
Description:

patched domain containing 1

Referenced in:

Hedgehog and Related Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         53           2
 C cysteine            2.5         22           2
 D aspartate           3.5         31           2
 E glutamate           5.1         45           2
 F phenylalanine       6.6         59           2
 G glycine             4.1         36           2
 H histidine           2.5         22           2
 I isoleucine          6.3         56           2
 K lysine              5.0         44           3
 L leucine            11.1         99           2
 M methionine          2.0         18           1
 N asparagine          4.6         41           2
 P proline             3.2         28           2
 Q glutamine           2.8         25           2
 R arginine            4.7         42           2
 S serine              8.3         74           3
 T threonine           7.1         63           2
 V valine              8.4         75           2
 W tryptophan          1.1         10           1
 Y tyrosine            5.1         45           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   patched domain containing 1 
C6orf138              0.439   hypothetical protein LOC442213 
PTCHD3                0.093   patched domain containing 3 
NPC1L1                0.037   Niemann-Pick C1-like protein 1 isoform 2 
NPC1                  0.036   Niemann-Pick disease, type C1 precursor 
PTCH1                 0.032   patched isoform S 
PTCH1                 0.032   patched isoform S 
PTCH1                 0.032   patched isoform S 
PTCH1                 0.032   patched isoform S 
PTCH1                 0.032   patched isoform L' 
PTCH1                 0.032   patched isoform M 
PTCH1                 0.032   patched isoform L 
NPC1L1                0.026   Niemann-Pick C1-like protein 1 isoform 1 
PTCH2                 0.022   patched 2 
HMGCR                 0.010   3-hydroxy-3-methylglutaryl-Coenzyme A reductase iso...
HMGCR                 0.010   3-hydroxy-3-methylglutaryl-Coenzyme A reductase isofo...
SCAP                  0.008   SREBF chaperone protein 
DISP1                 0.006   dispatched A 
XPR1                  0.004   xenotropic and polytropic retrovirus receptor isofor...
TYW3                  0.003   tRNA-yW synthesizing protein 3 homolog isoform 1 [Ho...
PKD2                  0.003   polycystin 2 
GPRC5A                0.003   G protein-coupled receptor, family C, group 5, member...
ZCRB1                 0.003   zinc finger CCHC-type and RNA binding motif 1 
PKD2L2                0.003   polycystic kidney disease 2-like 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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