Search of human proteins with 148231468

Search of human proteins with 148231468

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148231468 GDNF family receptor alpha like [Homo sapiens]
         (394 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148231468 GDNF family receptor alpha like [Homo sapiens]           834   0.0  
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...    75   1e-13
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...    75   1e-13
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...    75   1e-13
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap...    70   3e-12
gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap...    67   3e-11
gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Ho...    64   3e-10
gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Ho...    57   3e-08
gi|38490571 keratin associated protein 10-7 [Homo sapiens]             33   0.45 
gi|167466169 growth arrest-specific 1 [Homo sapiens]                   32   0.76 
gi|37693519 BMP-binding endothelial regulator precursor protein ...    32   1.3  
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho...    31   1.7  
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]            31   2.2  
gi|38490568 keratin associated protein 10-4 [Homo sapiens]             30   4.9  
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]     30   4.9  
gi|4885653 vascular endothelial growth factor C preproprotein [H...    29   6.5  
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             29   6.5  
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]          29   6.5  
gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]                         29   8.4  
gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]                         29   8.4  
gi|50345997 E1A binding protein p300 [Homo sapiens]                    29   8.4  
gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Ho...    29   8.4  

>gi|148231468 GDNF family receptor alpha like [Homo sapiens]
          Length = 394

 Score =  834 bits (2154), Expect = 0.0
 Identities = 394/394 (100%), Positives = 394/394 (100%)

Query: 1   MIVFIFLAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDSDPGDPCKM 60
           MIVFIFLAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDSDPGDPCKM
Sbjct: 1   MIVFIFLAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDSDPGDPCKM 60

Query: 61  RNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTR 120
           RNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTR
Sbjct: 61  RNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTR 120

Query: 121 SHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPF 180
           SHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPF
Sbjct: 121 SHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPF 180

Query: 181 NIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTF 240
           NIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTF
Sbjct: 181 NIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTF 240

Query: 241 QSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSE 300
           QSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSE
Sbjct: 241 QSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSE 300

Query: 301 ESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMT 360
           ESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMT
Sbjct: 301 ESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMT 360

Query: 361 VTCGILLLVMVKLRTSRISSKARDPSSIQIPGEL 394
           VTCGILLLVMVKLRTSRISSKARDPSSIQIPGEL
Sbjct: 361 VTCGILLLVMVKLRTSRISSKARDPSSIQIPGEL 394


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 17/160 (10%)

Query: 130 SCLEVAEACVGDVVCNAQLASYLKAC--SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187
           +CL+ A+AC  D +C    ++Y+  C  S + + C+ ++C  A+R F+  +P   +  + 
Sbjct: 148 NCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGML 207

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQR 247
           FC C   DI C + +       C+      P CL++  SC+ + +CR     F +     
Sbjct: 208 FCSCR--DIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT----- 260

Query: 248 VTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVL 287
               C  +   +S+  K++       DC  AY  ++GTV+
Sbjct: 261 ---NCQPESRSVSSCLKENYA-----DCLLAYSGLIGTVM 292


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 17/160 (10%)

Query: 130 SCLEVAEACVGDVVCNAQLASYLKAC--SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187
           +CL+ A+AC  D +C    ++Y+  C  S + + C+ ++C  A+R F+  +P   +  + 
Sbjct: 148 NCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGML 207

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQR 247
           FC C   DI C + +       C+      P CL++  SC+ + +CR     F +     
Sbjct: 208 FCSCR--DIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT----- 260

Query: 248 VTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVL 287
               C  +   +S+  K++       DC  AY  ++GTV+
Sbjct: 261 ---NCQPESRSVSSCLKENYA-----DCLLAYSGLIGTVM 292


>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
           [Homo sapiens]
          Length = 465

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 17/160 (10%)

Query: 130 SCLEVAEACVGDVVCNAQLASYLKAC--SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187
           +CL+ A+AC  D +C    ++Y+  C  S + + C+ ++C  A+R F+  +P   +  + 
Sbjct: 153 NCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGML 212

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQR 247
           FC C   DI C + +       C+      P CL++  SC+ + +CR     F +     
Sbjct: 213 FCSCR--DIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT----- 265

Query: 248 VTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVL 287
               C  +   +S+  K++       DC  AY  ++GTV+
Sbjct: 266 ---NCQPESRSVSSCLKENYA-----DCLLAYSGLIGTVM 297


>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
           sapiens]
          Length = 464

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 51/196 (26%), Positives = 81/196 (41%), Gaps = 19/196 (9%)

Query: 131 CLEVAEACVGDVVCNAQLASYLKACSANGNP---CDLKQCQAAIRFFYQNIPFNIAQMLA 187
           CL+ A+AC  +  C    +SY+  C+   +P   C+ ++C  A+R F+  +P      + 
Sbjct: 161 CLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRML 220

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKC--- 244
           FC C   D  C + +      +C+      P CL +   C+ D LCR     F + C   
Sbjct: 221 FCSC--QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRAS 278

Query: 245 WQRVTRKCHED--ENCISTLSKQDLTCSGSDDCKAAYIDI--LGTVLQVQCTCRTITQSE 300
           +Q VT  C  D  + C+ + +          D    Y+D    G V+   C+CR     E
Sbjct: 279 YQTVT-SCPADNYQACLGSYAGMI-----GFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332

Query: 301 ESLCKIFQHMLHRKSC 316
           E  C+ F        C
Sbjct: 333 EE-CEKFLRDFTENPC 347


>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
           sapiens]
          Length = 400

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 84/342 (24%), Positives = 133/342 (38%), Gaps = 61/342 (17%)

Query: 7   LAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDS--------DPGDPC 58
           LA G  L  E +   N+C   R +C  D   C  A+  + D+C  S        +P  P 
Sbjct: 28  LAAGDPLPTE-SRLMNSCLQARRKCQADPT-CSAAYHHL-DSCTSSISTPLPSEEPSVPA 84

Query: 59  -------KMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKL--LGKKCINKS---D 106
                  ++RNSS         +++      CL   D Y TV++   LG   ++ S   D
Sbjct: 85  DCLEAAQQLRNSSLIGCMCHRRMKNQVA---CL---DIYWTVHRARSLGNYELDVSPYED 138

Query: 107 NVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQ 166
            V    +K NL+ + +        CL+ A  C  +  C+    +Y +ACS  G  C    
Sbjct: 139 TVTSKPWKMNLS-KLNMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACS--GPHCQRHV 195

Query: 167 CQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRS 226
           C   +  F++      AQ L  C CA +D  C + +    +  CA+  V  P CL + R 
Sbjct: 196 CLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCALPPV-APNCLELRRL 254

Query: 227 CQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTV 286
           C +D LCR     FQ+ C            + + T + +         C  AY+ ++GT 
Sbjct: 255 CFSDPLCRSRLVDFQTHC---------HPMDILGTCATE------QSRCLRAYLGLIGTA 299

Query: 287 L------------QVQCTCRTITQSEESLCKIFQHMLHRKSC 316
           +             + CTCR     +E  C++ +       C
Sbjct: 300 MTPNFVSNVNTSVALSCTCRGSGNLQEE-CEMLEGFFSHNPC 340


>gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Homo
           sapiens]
          Length = 269

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 48/196 (24%), Positives = 76/196 (38%), Gaps = 16/196 (8%)

Query: 131 CLEVAEACVGDVVCNAQLASYLKAC---SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187
           C++ AEAC  D  C    + Y+  C   +A G  C   +C+ A+R F+   P  +   L 
Sbjct: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPALTHALL 84

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMV--PPPTCLSVIRSCQNDELCRRHYRTFQSKCW 245
           FC CA     C + +      +CA +     PP+CL  +  C+   +CR     FQ  C 
Sbjct: 85  FCPCAGP--ACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSC- 141

Query: 246 QRVTRKCHEDENCISTLSKQDLTCSGSDDCKAA---YIDILGTVLQVQCTCRTITQSEES 302
              T      + C+     + L         A    Y+D +   +   C C       E 
Sbjct: 142 ---TPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRRED 198

Query: 303 LCKIFQHMLHRKSCFN 318
            C+ F+ +  R  C +
Sbjct: 199 -CEAFRGLFTRNRCLD 213


>gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Homo
           sapiens]
          Length = 299

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 8/109 (7%)

Query: 131 CLEVAEACVGDVVCNAQLASYLKAC---SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187
           C++ AEAC  D  C    + Y+  C   +A G  C   +C+ A+R F+   P  +   L 
Sbjct: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPALTHALL 84

Query: 188 FCDCAQSDIPCQQSKEALHSKTCAVN--MVPPPTCLSVIRSCQNDELCR 234
           FC CA     C + +      +CA +     PP+CL  +  C+   +CR
Sbjct: 85  FCPCAGP--ACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCR 131


>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
          Length = 370

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 34/146 (23%), Positives = 45/146 (30%), Gaps = 38/146 (26%)

Query: 136 EACVGDVVCNAQLAS---YLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCA 192
           +AC   V C          +  CS + + C    CQ+A                    C 
Sbjct: 107 QACCVPVCCKTVCCKPVYCVPVCSGDSSCCQQSSCQSAC-------------------CT 147

Query: 193 QSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKC 252
            S  PCQQ+        C V +   P C  +  SC     C        S C Q V    
Sbjct: 148 SS--PCQQA--------CCVPICCKPVCSGISSSCCQQSSC---VSCVSSPCCQAVCEPS 194

Query: 253 HEDENCISTLSKQDLTCSGSDDCKAA 278
                CIS+ +    +C     CK A
Sbjct: 195 PCQSGCISSCTP---SCCQQSSCKPA 217


>gi|167466169 growth arrest-specific 1 [Homo sapiens]
          Length = 345

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 17/126 (13%)

Query: 81  KECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVG 140
           ++C C  D  C   K   + C+ ++                  G  G+  C E    C  
Sbjct: 126 EDCDCAQDENCKSTKRAIEPCLPRTSG----------GGAGGPGAGGVMGCTEARRRCDR 175

Query: 141 DVVCNAQLASYLKACSA--NGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIP- 197
           D  CN  L+ YL  C    NG  C   +C+  I      +    A +L  C C   + P 
Sbjct: 176 DSRCNLALSRYLTYCGKVFNGLRC-TDECRTVIE---DMLAMPKAALLNDCVCDGLERPI 231

Query: 198 CQQSKE 203
           C+  KE
Sbjct: 232 CESVKE 237


>gi|37693519 BMP-binding endothelial regulator precursor protein
           [Homo sapiens]
          Length = 685

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 18/77 (23%), Positives = 30/77 (38%)

Query: 178 IPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHY 237
           IPF        C C   ++ C++ K  + S+ CA+ +     C    + C  +       
Sbjct: 59  IPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSS 118

Query: 238 RTFQSKCWQRVTRKCHE 254
             +QS     V R+C E
Sbjct: 119 FKWQSPAEPCVLRQCQE 135


>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
           sapiens]
          Length = 353

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 36/124 (29%), Positives = 47/124 (37%), Gaps = 31/124 (25%)

Query: 12  SLENEYTSQTNNCTYLREQCL----RDANGCKHAWRVMEDACNDSD--PGDP-------- 57
           SL NE  S    C    + C     RD   C+  W + E AC D D    +P        
Sbjct: 187 SLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQF 246

Query: 58  CKMRNSSY----CNLS-IQYLVESNFQFKECL---------CTDDFYCTVNKLLGKKCIN 103
           CK  N SY    C+ S +    E     KEC+         C D   C+   L  K C+ 
Sbjct: 247 CKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECS---LAEKTCVR 303

Query: 104 KSDN 107
           K++N
Sbjct: 304 KNEN 307


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 13/66 (19%)

Query: 210 CAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTC 269
           C+VN +  P C  V + C N           +  C  R T +C ED  CIS L K    C
Sbjct: 464 CSVNGLCVPACDGV-KDCPNG--------LDERNCVCRATFQCKEDSTCIS-LPK---VC 510

Query: 270 SGSDDC 275
            G  DC
Sbjct: 511 DGQPDC 516


>gi|38490568 keratin associated protein 10-4 [Homo sapiens]
          Length = 401

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 32/146 (21%), Positives = 44/146 (30%), Gaps = 38/146 (26%)

Query: 136 EACVGDVVCNAQLAS---YLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCA 192
           +AC   V C          +  C  + + C    CQ+A                    C 
Sbjct: 107 QACCVPVCCKTVCCKPVCCVPVCCGDSSCCQQSSCQSAC-------------------CT 147

Query: 193 QSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKC 252
            S  PCQQ+        C V +   P C  +  SC     C        S C Q V    
Sbjct: 148 SS--PCQQA--------CCVPICCKPVCSGISSSCCQQSSC---VSCVSSPCCQAVCEPS 194

Query: 253 HEDENCISTLSKQDLTCSGSDDCKAA 278
                CIS+ +    +C     C+ A
Sbjct: 195 PCQSGCISSCTP---SCCQQSSCQPA 217


>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
          Length = 236

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 50/222 (22%), Positives = 78/222 (35%), Gaps = 53/222 (23%)

Query: 160 NPCDLKQCQAAIRFFYQNIPFNIAQML---AFCDCAQ--SDIPCQQSKEALHSKTCAVNM 214
           +PC+  +CQ        N    +AQ +   A C CA   +   CQ S     S  C V+ 
Sbjct: 27  DPCEKNRCQ--------NGGTCVAQAMLGKATCRCASGFTGEDCQYST----SHPCFVS- 73

Query: 215 VPPPTCLSVIRSCQNDELCRRHYR-TFQSKCWQRVTRK-CHEDENCISTLSKQDLTCSGS 272
                     R C N   C    R T++  C    T K C   + C+S       TC   
Sbjct: 74  ----------RPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTC--- 120

Query: 273 DDCKAAYIDILGTVLQVQCTCRTIT-------QSEESLCKIFQHMLHRKSCFNYPTLSNV 325
                       T +  Q +C+ +T       +++ + C I  H  H  +C N P     
Sbjct: 121 ------------TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQC 168

Query: 326 KGMALYTRKHANKITLTGFHSP-FNGEVIYAAMCMTVTCGIL 366
           + +  +T ++ + + +    SP  NG         T  C  L
Sbjct: 169 QCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210


>gi|4885653 vascular endothelial growth factor C preproprotein [Homo
           sapiens]
          Length = 419

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 14/98 (14%)

Query: 143 VCNAQLASYLKACSANGNPCDLKQCQAAI-RFFYQNIPFNIAQMLAFCDCAQSDIPCQQS 201
           VC  +L  +   C AN    D   CQ    R   +N P N  +    C+C +S   C   
Sbjct: 318 VCKNKL--FPSQCGAN-REFDENTCQCVCKRTCPRNQPLNPGKCA--CECTESPQKCLLK 372

Query: 202 KEALHSKTCAVNMVPPPTCLSVIRSCQ-----NDELCR 234
            +  H +TC+    P   C +  ++C+     ++E+CR
Sbjct: 373 GKKFHHQTCSCYRRP---CTNRQKACEPGFSYSEEVCR 407


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 10/54 (18%)

Query: 291  CT-CRTITQSE-ESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLT 342
            CT CR++TQ E E  C+         +C+N P +    G+++Y +K   K+ L+
Sbjct: 1011 CTLCRSLTQPEMEYDCE--------NACYNQPGMRASPGLSMYDQKKCEKLVLS 1056


>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
          Length = 379

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 3/64 (4%)

Query: 244 CWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSEESL 303
           CW  +    +E    I ++   + TC    DC A  +D+LG  L+    C    Q     
Sbjct: 21  CWSALWD--YETPKVIVSIRVHNATCLSDADCVAGELDMLGNGLRTG-RCVPYYQGPSKT 77

Query: 304 CKIF 307
           C++F
Sbjct: 78  CEVF 81


>gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]
          Length = 389

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 10/68 (14%)

Query: 233 CRRHYRT--FQSKCWQRVTRKCHEDENCIS--------TLSKQDLTCSGSDDCKAAYIDI 282
           CR  Y     + K +  VT KC + ++ +         +L  +  +C  SD  K   + +
Sbjct: 200 CRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLV 259

Query: 283 LGTVLQVQ 290
           +GT LQVQ
Sbjct: 260 MGTSLQVQ 267


>gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]
          Length = 352

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 10/68 (14%)

Query: 233 CRRHYRT--FQSKCWQRVTRKCHEDENCIS--------TLSKQDLTCSGSDDCKAAYIDI 282
           CR  Y     + K +  VT KC + ++ +         +L  +  +C  SD  K   + +
Sbjct: 163 CRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLV 222

Query: 283 LGTVLQVQ 290
           +GT LQVQ
Sbjct: 223 MGTSLQVQ 230


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 15/93 (16%)

Query: 148  LASYLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEAL-- 205
            + S + AC      C L  CQ   R         + Q    C   +++  C   K+ +  
Sbjct: 1739 IQSLVHACQCRNANCSLPSCQKMKR---------VVQHTKGCK-RKTNGGCPICKQLIAL 1788

Query: 206  ---HSKTCAVNMVPPPTCLSVIRSCQNDELCRR 235
               H+K C  N  P P CL++ +  +  +L  R
Sbjct: 1789 CCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHR 1821


>gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Homo
           sapiens]
          Length = 402

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 29/99 (29%), Positives = 39/99 (39%), Gaps = 27/99 (27%)

Query: 33  RDANGCKHAWRVMEDACNDSD--PGDP--------CKMRNSSY----CNLS-IQYLVESN 77
           RD   C+  W + E AC D D    +P        CK  N SY    C+ S +    E  
Sbjct: 261 RDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGP 320

Query: 78  FQFKECL---------CTDDFYCTVNKLLGKKCINKSDN 107
              KEC+         C D   C+   L  K C+ K++N
Sbjct: 321 GNCKECISGYAREHGQCADVDECS---LAEKTCVRKNEN 356


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.134    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,841,707
Number of Sequences: 37866
Number of extensions: 706672
Number of successful extensions: 1976
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1925
Number of HSP's gapped (non-prelim): 39
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.