Guide to the Human Genome
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Search of human proteins with 14150076

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14150076 Yip1 domain family, member 4 [Homo sapiens]
         (244 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14150076 Yip1 domain family, member 4 [Homo sapiens]               490   e-139
gi|28603852 Yip1 domain family, member 6 [Homo sapiens]                67   1e-11
gi|68226422 Yip1 domain family, member 5 [Homo sapiens]                64   9e-11
gi|32401427 Yip1 domain family, member 5 [Homo sapiens]                64   9e-11
gi|148664222 Yip1 domain family, member 7 [Homo sapiens]               61   1e-09
gi|10092643 Yip1 domain family, member 1 [Homo sapiens]                39   0.005
gi|13128976 Yip1 domain family, member 2 [Homo sapiens]                36   0.027
gi|226371746 peptide transporter 2 isoform a [Homo sapiens]            32   0.66 
gi|49472828 natural killer cell-specific antigen KLIP1 [Homo sap...    32   0.66 
gi|146219832 myosin light chain kinase 3 [Homo sapiens]                30   2.5  
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec...    29   3.3  
gi|5902022 PL6 protein [Homo sapiens]                                  28   5.6  
gi|33457301 glycerophosphodiester phosphodiesterase domain conta...    28   5.6  
gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]     28   7.3  
gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]     28   7.3  
gi|27477115 ATP-binding cassette, sub-family A, member 9 [Homo s...    28   7.3  
gi|50233864 olfactory receptor, family 2, subfamily L, member 8 ...    28   9.5  

>gi|14150076 Yip1 domain family, member 4 [Homo sapiens]
          Length = 244

 Score =  490 bits (1261), Expect = e-139
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGY 60
           MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGY
Sbjct: 1   MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGY 60

Query: 61  GWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLA 120
           GWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLA
Sbjct: 61  GWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLA 120

Query: 121 VVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIV 180
           VVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIV
Sbjct: 121 VVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIV 180

Query: 181 IAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSL 240
           IAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSL
Sbjct: 181 IAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSL 240

Query: 241 YTGV 244
           YTGV
Sbjct: 241 YTGV 244


>gi|28603852 Yip1 domain family, member 6 [Homo sapiens]
          Length = 236

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 51/182 (28%), Positives = 92/182 (50%), Gaps = 20/182 (10%)

Query: 67  EDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFS 126
           E D    N+ +   +  DLK +  K   VL P  S      ++RD  D WGPL + +  +
Sbjct: 48  EFDSSTLNESVRNTIMRDLKAVGKKFMHVLYPRKS----NTLLRDW-DLWGPLILCVTLA 102

Query: 127 MI--------SLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPL 178
           ++           G  +     + +W FG++TI L +++LGG +++ Q L V+GY +LPL
Sbjct: 103 LMLQRDSADSEKDGGPQFAEVFVIVW-FGAVTITLNSKLLGGNISFFQSLCVLGYCILPL 161

Query: 179 IVIAPV--LLVVGSFEVVSTLIKLFGVF----WAAYSAASLLVGEEFKTKKPLLIYPIFL 232
            V   +  L+++     V+ +++LF V     W+  ++ +LL   +   ++ L +YP+FL
Sbjct: 162 TVAMLICRLVLLADPGPVNFMVRLFVVIVMFAWSIVASTALLADSQPPNRRALAVYPVFL 221

Query: 233 LY 234
            Y
Sbjct: 222 FY 223


>gi|68226422 Yip1 domain family, member 5 [Homo sapiens]
          Length = 257

 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 50/170 (29%), Positives = 79/170 (46%), Gaps = 9/170 (5%)

Query: 72  EDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLY 131
           ED  PLLEEL I+   I+ K   VL P+     +   + +  D  GP+   L F    L 
Sbjct: 87  EDEPPLLEELGINFDHIWQKTLTVLHPLKVADGS---IMNETDLAGPMVFCLAFGATLLL 143

Query: 132 G---QFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVV 188
               QF  V  I  I   G   +  L  + G  V++G V  V+GY LLP+I+++   ++ 
Sbjct: 144 AGKIQFGYVYGISAIGCLGMFCLLNLMSMTG--VSFGCVASVLGYCLLPMILLSSFAVIF 201

Query: 189 GSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLI-YPIFLLYIYF 237
               +V  ++    + W ++SA+ + +       + LL+ YP  LLY  F
Sbjct: 202 SLQGMVGIILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVF 251


>gi|32401427 Yip1 domain family, member 5 [Homo sapiens]
          Length = 257

 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 50/170 (29%), Positives = 79/170 (46%), Gaps = 9/170 (5%)

Query: 72  EDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLY 131
           ED  PLLEEL I+   I+ K   VL P+     +   + +  D  GP+   L F    L 
Sbjct: 87  EDEPPLLEELGINFDHIWQKTLTVLHPLKVADGS---IMNETDLAGPMVFCLAFGATLLL 143

Query: 132 G---QFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVV 188
               QF  V  I  I   G   +  L  + G  V++G V  V+GY LLP+I+++   ++ 
Sbjct: 144 AGKIQFGYVYGISAIGCLGMFCLLNLMSMTG--VSFGCVASVLGYCLLPMILLSSFAVIF 201

Query: 189 GSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLI-YPIFLLYIYF 237
               +V  ++    + W ++SA+ + +       + LL+ YP  LLY  F
Sbjct: 202 SLQGMVGIILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVF 251


>gi|148664222 Yip1 domain family, member 7 [Homo sapiens]
          Length = 280

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 53/203 (26%), Positives = 93/203 (45%), Gaps = 18/203 (8%)

Query: 43  GDFIKESTATTFLRQRGYGWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSL 102
           G F + ++ + +  Q  Y   ++  D++P    PLLEEL I    I+ K   VL PM  +
Sbjct: 88  GQFFQPASNSDYYSQSPY---IDSFDEEP----PLLEELGIHFDHIWQKTLTVLNPMKPV 140

Query: 103 GFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGE- 161
             +   + +  D  GP+   +      L        ++  +   G L I  L  ++    
Sbjct: 141 DGS---IMNETDLTGPILFCVALGATLLLAGKVQFGYVYGMSAIGCLVIHALLNLMSSSG 197

Query: 162 VAYGQVLGVIGYSLLPLIVI---APVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEE 218
           V+YG V  V+GY LLP++++   A    + G F ++S+L+    + W + SA+ + +   
Sbjct: 198 VSYGCVASVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVI---IGWCSLSASKIFIAAL 254

Query: 219 FKTKKPLLI-YPIFLLYIYFLSL 240
               + LL+ YP  +LY  F  L
Sbjct: 255 HMEGQQLLVAYPCAILYGLFALL 277


>gi|10092643 Yip1 domain family, member 1 [Homo sapiens]
          Length = 306

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 40/129 (31%)

Query: 82  DIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPL---AVVLFFSMIS--------- 129
           D+D   ++ +I+  L+P+P   F R  +R NPD +GP    A ++F   IS         
Sbjct: 87  DVDTYQVFDRIKGSLLPIPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIH 146

Query: 130 -------LYGQFRVVS----------WIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIG 172
                     +FR VS          W++ + ++G    FL+ R         +V+ ++ 
Sbjct: 147 LGEKTYHYVPEFRKVSIAATIIYAYAWLVPLALWG----FLMWR-------NSKVMNIVS 195

Query: 173 YSLLPLIVI 181
           YS L ++ +
Sbjct: 196 YSFLEIVCV 204


>gi|13128976 Yip1 domain family, member 2 [Homo sapiens]
          Length = 316

 Score = 36.2 bits (82), Expect = 0.027
 Identities = 45/188 (23%), Positives = 75/188 (39%), Gaps = 40/188 (21%)

Query: 82  DIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGP------LAVVLFFS--------- 126
           D+D   +  +I+  L+P P   F R  +R+ PD +GP      LA VL  +         
Sbjct: 88  DVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQ 147

Query: 127 ----MISLYGQFRVV----------SWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIG 172
                I    QF  V          +W++ + ++G L      +   G   + + + + G
Sbjct: 148 RRDPSIHYSPQFHKVTVAGISIYCYAWLVPLALWGFLRWRKGVQERMGPYTFLETVCIYG 207

Query: 173 YSLLPLIVIAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASL------LVGEEFKTKKPLL 226
           YSL   I +  + L+      V  L  LFG      SAA L      +V E+ +    +L
Sbjct: 208 YSLFVFIPMVVLWLI-----PVPWLQWLFGALALGLSAAGLVFTLWPVVREDTRLVATVL 262

Query: 227 IYPIFLLY 234
           +  + LL+
Sbjct: 263 LSVVVLLH 270


>gi|226371746 peptide transporter 2 isoform a [Homo sapiens]
          Length = 729

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 8/93 (8%)

Query: 129 SLYGQFRVVSWIITIWIFGSLTIFLLAR-VLGGEVAYGQVLGVIGYSLLPLIV--IAPVL 185
           S  G+F+ + ++  +++ G +   L A  +LGG+V +  VL +IG SL+ L    I P +
Sbjct: 106 SWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVH-TVLSLIGLSLIALGTGGIKPCV 164

Query: 186 LVVGSFEV----VSTLIKLFGVFWAAYSAASLL 214
              G  +          + F VF+ + +A SL+
Sbjct: 165 AAFGGDQFEEKHAEERTRYFSVFYLSINAGSLI 197


>gi|49472828 natural killer cell-specific antigen KLIP1 [Homo
           sapiens]
          Length = 350

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 37/182 (20%), Positives = 73/182 (40%), Gaps = 36/182 (19%)

Query: 82  DIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFR------ 135
           D++   +  ++   ++P+  + F +++  +    +GPL +V     I L+G         
Sbjct: 123 DVEPAQVRSRLLESMIPIKMVNFPQKIAGE---LYGPLMLVFTLVAILLHGMKTSDTIIR 179

Query: 136 -------VVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVV 188
                   +      W+  S  I+ LA +   ++   Q+L ++GY L    +   VL + 
Sbjct: 180 EGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCI---VLFIT 236

Query: 189 GSFEVVSTLIKLFGVFWAAYSAAS------LLVGEEFKTKKPLL-------IYPIFLLYI 235
            +      L  LF +FW      S      +LV       + LL       ++ +FLLY+
Sbjct: 237 YNIH----LHALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYL 292

Query: 236 YF 237
           +F
Sbjct: 293 HF 294


>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
          Length = 819

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 19/58 (32%), Positives = 26/58 (44%)

Query: 23  ADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGYGWLLEVEDDDPEDNKPLLEE 80
           A  E L   +A+ D  + L G   ++S    FL Q    W      D PE+NK  +EE
Sbjct: 109 ARLEALFRMVAAVDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEE 166


>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
           precursor [Homo sapiens]
          Length = 943

 Score = 29.3 bits (64), Expect = 3.3
 Identities = 17/67 (25%), Positives = 31/67 (46%)

Query: 143 IWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVVGSFEVVSTLIKLFG 202
           + ++  L + +    L  EV       ++G SLLP+  +AP  ++ G F + S +     
Sbjct: 621 VLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGV 680

Query: 203 VFWAAYS 209
           V W  +S
Sbjct: 681 VLWEVFS 687


>gi|5902022 PL6 protein [Homo sapiens]
          Length = 351

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 16/88 (18%)

Query: 116 WGPLAVVLFFSMISL-YGQFRVVSWIITIWIFGSLTIFLLARV------LGGE-VAYGQV 167
           WG L +++FFS++++  G     ++++T     +L      R+      LGG  VA  Q 
Sbjct: 93  WGALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTVRIHGALGFLGGVLVALKQT 152

Query: 168 LG--------VIGYSLLPLIVIAPVLLV 187
           +G         +  S++P++++A +LL+
Sbjct: 153 MGDCVVLRVPQVRVSVMPMLLLALLLLL 180


>gi|33457301 glycerophosphodiester phosphodiesterase domain
           containing 4 [Homo sapiens]
          Length = 520

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 7/59 (11%)

Query: 122 VLFFSMISLYGQFRVVSWIITI----WIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLL 176
           +L F  I    ++    W+  +    W F S+ I  LAR+L    AY  +L ++G+ LL
Sbjct: 1   MLLFLWIETSSEYFNFDWVTFLGTGYWFFWSIFILSLARIL---TAYSSLLLLLGFLLL 56


>gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]
          Length = 572

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 4/35 (11%)

Query: 3   PPGPPPAYAPTNGDFTFVSSADAEDL--SGSIASP 35
           PP PPP Y P   ++T  S  DA+ +  +GS+ SP
Sbjct: 147 PPVPPPPYYPP--EYTCSSETDAQSITYNGSMDSP 179


>gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]
          Length = 668

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 4/35 (11%)

Query: 3   PPGPPPAYAPTNGDFTFVSSADAEDL--SGSIASP 35
           PP PPP Y P   ++T  S  DA+ +  +GS+ SP
Sbjct: 243 PPVPPPPYYPP--EYTCSSETDAQSITYNGSMDSP 275


>gi|27477115 ATP-binding cassette, sub-family A, member 9 [Homo
           sapiens]
          Length = 1624

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 1/70 (1%)

Query: 174 SLLPLIVIAPVLLVVGSFEVVSTLIKLFGVFWAAYS-AASLLVGEEFKTKKPLLIYPIFL 232
           +L+ LIV +  ++V+  F +V TL  L+G+     +   S+L+ + F T   + +  +F 
Sbjct: 283 TLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLVVFLLIVFW 342

Query: 233 LYIYFLSLYT 242
             + F +LYT
Sbjct: 343 GILGFPALYT 352


>gi|50233864 olfactory receptor, family 2, subfamily L, member 8
           [Homo sapiens]
          Length = 312

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 138 SWIITIWIFGSLTIFLLARVLGGEVAYGQVL 168
           +W+    +F S TIFL+   +G   +YGQVL
Sbjct: 191 TWVYEGTVFLSATIFLVFPFIGISCSYGQVL 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.145    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,735,828
Number of Sequences: 37866
Number of extensions: 428769
Number of successful extensions: 1462
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1448
Number of HSP's gapped (non-prelim): 17
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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