Search of human proteins with 85861202

Search of human proteins with 85861202

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|85861202 carcinoembryonic antigen-related cell adhesion
molecule 16 [Homo sapiens]
         (484 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|85861202 carcinoembryonic antigen-related cell adhesion molec...   970   0.0  
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...   178   9e-45
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...   178   9e-45
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...   177   2e-44
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...   174   1e-43
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [...   169   5e-42
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   167   3e-41
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   167   3e-41
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1...   166   4e-41
gi|21314600 carcinoembryonic antigen-related cell adhesion molec...   164   1e-40
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi...   160   3e-39
gi|148612793 carcinoembryonic antigen-related cell adhesion mole...   151   1e-36
gi|52317156 carcinoembryonic antigen-related cell adhesion molec...   150   2e-36
gi|156564378 carcinoembryonic antigen-related cell adhesion mole...   144   1e-34
gi|156564393 carcinoembryonic antigen-related cell adhesion mole...   144   1e-34
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi...   134   2e-31
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi...   133   4e-31
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [...   132   5e-31
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H...   132   7e-31
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [...   132   7e-31
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu...   129   6e-30
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [...   128   1e-29
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ...   127   2e-29
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ...   127   2e-29
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]   126   4e-29
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2...   105   9e-23
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2...   105   9e-23
gi|122937205 carcinoembryonic antigen-related cell adhesion mole...   104   2e-22
gi|156564390 carcinoembryonic antigen-related cell adhesion mole...   103   3e-22
gi|156564388 carcinoembryonic antigen-related cell adhesion mole...   103   3e-22

>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
           16 [Homo sapiens]
          Length = 484

 Score =  970 bits (2507), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MSDLLSIYSAPVVVSTVLHMLQIRKLRLGRVHKLPRVLEVGNSGTMSRAYTFFFLRWSFM 60
           MSDLLSIYSAPVVVSTVLHMLQIRKLRLGRVHKLPRVLEVGNSGTMSRAYTFFFLRWSFM
Sbjct: 1   MSDLLSIYSAPVVVSTVLHMLQIRKLRLGRVHKLPRVLEVGNSGTMSRAYTFFFLRWSFM 60

Query: 61  ALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSV 120
           ALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSV
Sbjct: 61  ALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSV 120

Query: 121 SYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGY 180
           SYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGY
Sbjct: 121 SYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGY 180

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
           GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP
Sbjct: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300
           DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK
Sbjct: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300

Query: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTL 360
           VDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTL
Sbjct: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTL 360

Query: 361 LSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRL 420
           LSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRL
Sbjct: 361 LSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRL 420

Query: 421 LSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
           LSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV
Sbjct: 421 LSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480

Query: 481 APLG 484
           APLG
Sbjct: 481 APLG 484


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score =  178 bits (452), Expect = 9e-45
 Identities = 112/326 (34%), Positives = 163/326 (50%), Gaps = 21/326 (6%)

Query: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A   TF N      +T E  P   +EG  V L+VH L  +L  YSWY G  +  + 
Sbjct: 18  LLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNR 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            +  Y + T   TPGPA++GRE + P+ SL IQ +    +G Y LQ     L  E   G 
Sbjct: 78  QIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
             V+  L +P++ +N++  VE +D +   C   +      W+ N  +LPV+ RL LS   
Sbjct: 138 FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGN 197

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAIL-QDSTTRTGCTIKV 301
           R L    + R + G Y+CE+ NPVS +RS+P+ L V +GP+   I   D+  R G     
Sbjct: 198 RTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPG----- 252

Query: 302 DFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLL 361
               +L+L C + S P  +Y W  NG   ++ Q+ L I ++T    G+YTC A N+ T  
Sbjct: 253 ---ANLSLSCYAASNPPAQYSWLINGTFQQSTQE-LFIPNITVNNSGSYTCHANNSVT-- 306

Query: 362 SGSASVVVKLSAAAVATMIVPVPTKP 387
            G     VK     + T + PV  KP
Sbjct: 307 -GCNRTTVK---TIIVTELSPVVAKP 328



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 34/97 (35%), Positives = 61/97 (62%)

Query: 184 QVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGR 243
           ++  ++A+P + A+ T +   +D++ L CS+      +RWFF   +LP + R+ LS    
Sbjct: 320 ELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNT 379

Query: 244 VLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYF 280
            L+ + ++RE+AG Y CEV+NP+S ++S+PI L V +
Sbjct: 380 TLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 2/102 (1%)

Query: 383 VPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTGREV 440
           +P    EG++V L V   P+ L  Y+WY+G   + NR +     GT  A  GPA++GRE 
Sbjct: 41  MPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRET 100

Query: 441 GFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
            +PN SLL+Q +   DTG YTL+ +      E    +  V P
Sbjct: 101 IYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYP 142


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score =  178 bits (452), Expect = 9e-45
 Identities = 112/326 (34%), Positives = 163/326 (50%), Gaps = 21/326 (6%)

Query: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A   TF N      +T E  P   +EG  V L+VH L  +L  YSWY G  +  + 
Sbjct: 18  LLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNR 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            +  Y + T   TPGPA++GRE + P+ SL IQ +    +G Y LQ     L  E   G 
Sbjct: 78  QIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
             V+  L +P++ +N++  VE +D +   C   +      W+ N  +LPV+ RL LS   
Sbjct: 138 FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGN 197

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAIL-QDSTTRTGCTIKV 301
           R L    + R + G Y+CE+ NPVS +RS+P+ L V +GP+   I   D+  R G     
Sbjct: 198 RTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPG----- 252

Query: 302 DFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLL 361
               +L+L C + S P  +Y W  NG   ++ Q+ L I ++T    G+YTC A N+ T  
Sbjct: 253 ---ANLSLSCYAASNPPAQYSWLINGTFQQSTQE-LFIPNITVNNSGSYTCHANNSVT-- 306

Query: 362 SGSASVVVKLSAAAVATMIVPVPTKP 387
            G     VK     + T + PV  KP
Sbjct: 307 -GCNRTTVK---TIIVTELSPVVAKP 328



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 34/97 (35%), Positives = 61/97 (62%)

Query: 184 QVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGR 243
           ++  ++A+P + A+ T +   +D++ L CS+      +RWFF   +LP + R+ LS    
Sbjct: 320 ELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNT 379

Query: 244 VLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYF 280
            L+ + ++RE+AG Y CEV+NP+S ++S+PI L V +
Sbjct: 380 TLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 2/102 (1%)

Query: 383 VPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTGREV 440
           +P    EG++V L V   P+ L  Y+WY+G   + NR +     GT  A  GPA++GRE 
Sbjct: 41  MPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRET 100

Query: 441 GFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
            +PN SLL+Q +   DTG YTL+ +      E    +  V P
Sbjct: 101 IYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYP 142


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score =  177 bits (448), Expect = 2e-44
 Identities = 116/357 (32%), Positives = 177/357 (49%), Gaps = 17/357 (4%)

Query: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A   TF N      +T+E  P   +EG  V L+VH L   L  YSWY G  +  + 
Sbjct: 18  LLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNR 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            +  Y++ T   TPGPA++GRE + P+ SL IQ I+   +G Y L      L  E   G 
Sbjct: 78  QIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQ 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
            +V+  L +P++ +N++  VE +D +   C   +  A   W+ N  +LPV+ RL LS   
Sbjct: 138 FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGN 197

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTT-RTGCTIKV 301
           R L    + R +  +Y+CE  NPVS  RS+ + L V +GP+   I   +T+ R+G     
Sbjct: 198 RTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG----- 252

Query: 302 DFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLL 361
               +L L C + S P  +Y W  NG   ++ Q+ L I ++T    G+YTC A N+ T L
Sbjct: 253 ---ENLNLSCHAASNPPAQYSWFVNGTFQQSTQE-LFIPNITVNNSGSYTCQAHNSDTGL 308

Query: 362 SGSASVVVKLSAAAVATMIVPVPTKPTEGQD-VTLTVQGYPKDLLVYAWYRGPASEP 417
           + +    + + A      I    + P E +D V LT +   ++   Y W+    S P
Sbjct: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQN-TTYLWWVNNQSLP 364



 Score =  109 bits (272), Expect = 6e-24
 Identities = 94/352 (26%), Positives = 139/352 (39%), Gaps = 48/352 (13%)

Query: 84  TLEPAQPS--EGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHT 141
           T+ P   S   G+N+ L  H  S     YSW+   T   S                    
Sbjct: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQS-------------------- 280

Query: 142 GREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILA-----QPTVLA 196
                     L I  I   +SG+Y  Q  N    ++ G     V  I       +P + +
Sbjct: 281 -------TQELFIPNITVNNSGSYTCQAHN----SDTGLNRTTVTTITVYAEPPKPFITS 329

Query: 197 NSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAG 256
           N++  VE  D + L C          W+ N  +LPV+ RL LS D R L    + R + G
Sbjct: 330 NNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVG 389

Query: 257 AYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSLTLWCVSRS 315
            Y+C + N +SV  S+P+ L V +GP+   I    T  R G         +L+L C + S
Sbjct: 390 PYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPG--------VNLSLSCHAAS 441

Query: 316 CPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAA 375
            P  +Y W  +G   ++ Q+ L IS++T    G YTC A N+ +  S +    + +SA  
Sbjct: 442 NPPAQYSWLIDGNIQQHTQE-LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAEL 500

Query: 376 VATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
               I    +KP E +D              Y W+    S P     QL +G
Sbjct: 501 PKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552



 Score =  104 bits (260), Expect = 2e-22
 Identities = 73/232 (31%), Positives = 110/232 (47%), Gaps = 19/232 (8%)

Query: 152 LDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEI-----LAQPTVLANSTALVERRD 206
           L I  I  ++SG Y  Q  N    +  G+    V  I     L +P++ +N++  VE +D
Sbjct: 462 LFISNITEKNSGLYTCQANN----SASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKD 517

Query: 207 TLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPV 266
            +   C   +      W+ NG +LPV+ RL LS   R L    + R +A AY C + N V
Sbjct: 518 AVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSV 577

Query: 267 SVSRSEPINLTVYFGPERVAIL-QDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTF 325
           S +RS+P+ L V +GP+   I   DS+  +G         +L L C S S P P+Y W  
Sbjct: 578 SANRSDPVTLDVLYGPDTPIISPPDSSYLSG--------ANLNLSCHSASNPSPQYSWRI 629

Query: 326 NGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVA 377
           NG   ++ Q  L I+ +T    GTY C   N  T  + S    + +SA+  +
Sbjct: 630 NGIPQQHTQ-VLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTS 680



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 2/105 (1%)

Query: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTG 437
           I   P    EG++V L V   P+ L  Y+WY+G   + NR +     GT  A  GPA++G
Sbjct: 38  IESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSG 97

Query: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
           RE+ +PN SLL+Q +   DTG YTL  +      E    + +V P
Sbjct: 98  REIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYP 142


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score =  174 bits (442), Expect = 1e-43
 Identities = 99/305 (32%), Positives = 154/305 (50%), Gaps = 10/305 (3%)

Query: 73  TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVS 130
           TF N      +T+E  P   +EG  V L+ H L    + YSWY G  +  + L+  Y++ 
Sbjct: 26  TFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIG 85

Query: 131 TGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILA 190
           T   TPGPA++GRE + P+ SL IQ +    +G Y LQ     L  E   G   V+  L 
Sbjct: 86  TQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELP 145

Query: 191 QPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGI 250
           +P++ +N++  VE +D +   C          W+ NG +LPV+ RL LS     L    +
Sbjct: 146 KPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSV 205

Query: 251 RREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLW 310
           +R +AG+Y+CE+ NP S +RS+P+ L V +GP       D  T +          +L L 
Sbjct: 206 KRNDAGSYECEIQNPASANRSDPVTLNVLYGP-------DGPTISPSKANYRPGENLNLS 258

Query: 311 CVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK 370
           C + S P  +Y W  NG   ++ Q+ L I ++T    G+Y C A N+ T L+ +   ++ 
Sbjct: 259 CHAASNPPAQYSWFINGTFQQSTQE-LFIPNITVNNSGSYMCQAHNSATGLNRTTVTMIT 317

Query: 371 LSAAA 375
           +S +A
Sbjct: 318 VSGSA 322



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 37/105 (35%), Positives = 54/105 (51%), Gaps = 2/105 (1%)

Query: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTG 437
           I   P    EG++V L     P++ + Y+WY+G   + N L+     GT  A  GPA++G
Sbjct: 38  IESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSG 97

Query: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
           RE  +PN SLL+Q +   DTG YTL+ +      E    +  V P
Sbjct: 98  RETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYP 142


>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
           [Homo sapiens]
          Length = 326

 Score =  169 bits (428), Expect = 5e-42
 Identities = 106/313 (33%), Positives = 162/313 (51%), Gaps = 17/313 (5%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           +LL+A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  VLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            + SY+V       GPA++GRE V  + SL IQ +    +G+Y L    R+  T    GH
Sbjct: 78  YITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGH 137

Query: 183 VQ--VHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               +H    +P++ +++    E  + + L C   +P A  +W+ NG +LP+  RL LS 
Sbjct: 138 FTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSK 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTI 299
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +  GP+  +I    T  R+G   
Sbjct: 198 TNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPDLPSIYPSFTYYRSG--- 254

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKT 359
                 +L L C + S P  +Y WT NG+   +GQ  L+I  +T    G Y C  +N+ T
Sbjct: 255 -----ENLYLSCFAESNPRAQYSWTINGKFQLSGQ-KLSIPQITTKHSGLYACSVRNSAT 308

Query: 360 LLSGSASVVVKLS 372
               S S+ VK+S
Sbjct: 309 GKESSKSITVKVS 321



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTGREVG 441
           P K +EG+DV L V   P++L  Y WY+G  +     ++   +     I GPA++GRE  
Sbjct: 42  PPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERV 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  +
Sbjct: 102 YSNASLLIQNVTQEDAGSYTLHII 125


>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  167 bits (422), Expect = 3e-41
 Identities = 105/314 (33%), Positives = 160/314 (50%), Gaps = 17/314 (5%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN     + A+++I   P + SEG +V L+VH L   L  Y WY G  + + +
Sbjct: 18  LLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180
            + SY+V       GPA+TGRE V  + SL IQ +    +G+Y L    R  +T    GY
Sbjct: 78  YITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGY 137

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               ++  L +P +  N++   E +D L   C   S      W+ NG +LPV+ R+    
Sbjct: 138 FTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPI 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTI 299
           + R+L    + R E G Y+CE+ +     RS+P+ L V +GP+  +I    T  R+G   
Sbjct: 198 ENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSG--- 254

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKT 359
                 +L L C + S P  EY WT NG+  ++GQ  L+I  +T    G YTC  +N+ T
Sbjct: 255 -----ENLYLSCFAESNPPAEYFWTINGKFQQSGQ-KLSIPQITTKHRGLYTCSVRNSAT 308

Query: 360 LLSGSASVVVKLSA 373
               S S+ V++SA
Sbjct: 309 GKESSKSMTVEVSA 322



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 2/88 (2%)

Query: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTG 437
           I  +P K +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA+TG
Sbjct: 38  IEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTG 97

Query: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTV 465
           RE  + N SLL+Q +   D G YTL  +
Sbjct: 98  RETVYSNASLLIQNVTREDAGSYTLHII 125


>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  167 bits (422), Expect = 3e-41
 Identities = 105/314 (33%), Positives = 160/314 (50%), Gaps = 17/314 (5%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN     + A+++I   P + SEG +V L+VH L   L  Y WY G  + + +
Sbjct: 18  LLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180
            + SY+V       GPA+TGRE V  + SL IQ +    +G+Y L    R  +T    GY
Sbjct: 78  YITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGY 137

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               ++  L +P +  N++   E +D L   C   S      W+ NG +LPV+ R+    
Sbjct: 138 FTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPI 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTI 299
           + R+L    + R E G Y+CE+ +     RS+P+ L V +GP+  +I    T  R+G   
Sbjct: 198 ENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSG--- 254

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKT 359
                 +L L C + S P  EY WT NG+  ++GQ  L+I  +T    G YTC  +N+ T
Sbjct: 255 -----ENLYLSCFAESNPPAEYFWTINGKFQQSGQ-KLSIPQITTKHRGLYTCSVRNSAT 308

Query: 360 LLSGSASVVVKLSA 373
               S S+ V++SA
Sbjct: 309 GKESSKSMTVEVSA 322



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 2/88 (2%)

Query: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTG 437
           I  +P K +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA+TG
Sbjct: 38  IEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTG 97

Query: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTV 465
           RE  + N SLL+Q +   D G YTL  +
Sbjct: 98  RETVYSNASLLIQNVTREDAGSYTLHII 125


>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
           [Homo sapiens]
          Length = 335

 Score =  166 bits (420), Expect = 4e-41
 Identities = 103/321 (32%), Positives = 160/321 (49%), Gaps = 13/321 (4%)

Query: 55  LRWSFMALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYA 114
           ++W  + LT    LLL+   L   A++ I  +P + SEG +V L+VH L   L  Y WY 
Sbjct: 13  IKWKGLLLTA---LLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYK 69

Query: 115 GPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQL 174
           G    + + + SY+V       GPA++GRE V  + SL IQ +    +G+Y L    R  
Sbjct: 70  GQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIIKRGD 129

Query: 175 QTE--VGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPV 232
            T    GY    ++    +P++ +++    E  +T+ L C+  +P A   W+ NG +LP+
Sbjct: 130 GTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPM 189

Query: 233 ALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST 292
             R+ LS   R L   G+ +  AG Y+CE+WN  S SRS+P+ L +  GP+   I    T
Sbjct: 190 THRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVT 249

Query: 293 TRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTC 352
           +            +L L C + S P  +Y WT NG+   +GQ  L I  +T    G Y C
Sbjct: 250 SYYS-------GENLDLSCFANSNPPAQYSWTINGKFQLSGQ-KLFIPQITPKHNGLYAC 301

Query: 353 IAKNTKTLLSGSASVVVKLSA 373
            A+N+ T    S S+ +++ A
Sbjct: 302 SARNSATGEESSTSLTIRVIA 322



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 33/89 (37%), Positives = 48/89 (53%), Gaps = 2/89 (2%)

Query: 379 MIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHT 436
           MI   P K +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA++
Sbjct: 37  MIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYS 96

Query: 437 GREVGFPNCSLLVQKLNLTDTGRYTLKTV 465
           GRE  + N SLL+Q +   D G YTL  +
Sbjct: 97  GRETVYSNASLLIQNVTREDAGSYTLHII 125


>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
           8 [Homo sapiens]
          Length = 349

 Score =  164 bits (416), Expect = 1e-40
 Identities = 97/314 (30%), Positives = 155/314 (49%), Gaps = 13/314 (4%)

Query: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A   TF N      +T+E  P+  +EG  V L+VH L  +   Y+WY G T+  + 
Sbjct: 18  LLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANR 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            +  Y++S    TPGPA++ RE + P+ SL ++ +    +G+Y LQ     L +E   G 
Sbjct: 78  RIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQ 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
             VH    +P++ +N++  VE +D +   C   +      W+ NG +LPV+ RL LS   
Sbjct: 138 FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGN 197

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVD 302
           R L    + R + G Y+CE+ NP S + S+P+ L V +GP+   I    T          
Sbjct: 198 RTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDT-------YYH 250

Query: 303 FNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLS 362
              +L L C + S P  +Y W+ NG   +     L I ++T    G+Y C   N+ T  +
Sbjct: 251 AGVNLNLSCHAASNPPSQYSWSVNG-TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRN 309

Query: 363 GSASVVVKLSAAAV 376
            +   ++ +S A V
Sbjct: 310 RTTVRMITVSDALV 323



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNR-LLSQLPSGTWIA-GPAHTG 437
           I  VP+   EG++V L V   P+D   Y WY+G   + NR ++  + S   I  GPA++ 
Sbjct: 38  IEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSN 97

Query: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
           RE  +PN SLL++ +   DTG YTL+ + +   +E +  +  V P
Sbjct: 98  RETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHP 142


>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
           sapiens]
          Length = 335

 Score =  160 bits (404), Expect = 3e-39
 Identities = 102/315 (32%), Positives = 159/315 (50%), Gaps = 17/315 (5%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LL++A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180
            + SY+V       GPA++GRE    + SL IQ +    +G+Y L    R   T    GY
Sbjct: 78  YITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGY 137

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               ++    +P++ +++    E  +T+ L C   +P    +W+ NG +LP+  R  LS 
Sbjct: 138 FTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSE 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTT-RTGCTI 299
             R L   G+ +  AG Y+CE+ N  S SRS+P+ L +  GP+   I    T  R+G   
Sbjct: 198 TNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRIHPSYTNYRSG--- 254

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKT 359
                 +L L C + S P  +Y WT NG+  ++GQ +L I  +T    G Y C  +N+ T
Sbjct: 255 -----DNLYLSCFANSNPPAQYSWTINGKFQQSGQ-NLFIPQITTKHSGLYVCSVRNSAT 308

Query: 360 LLSGSASVVVKLSAA 374
               S S+ VK+SA+
Sbjct: 309 GEESSTSLTVKVSAS 323



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTGREVG 441
           P K +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA++GRE  
Sbjct: 42  PPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETA 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  +
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHII 125


>gi|148612793 carcinoembryonic antigen-related cell adhesion
           molecule isoform 1 [Homo sapiens]
          Length = 293

 Score =  151 bits (381), Expect = 1e-36
 Identities = 88/226 (38%), Positives = 126/226 (55%), Gaps = 6/226 (2%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ L        A + I   P + +EG+NV L V  L   L +Y WY G T+  + 
Sbjct: 18  LLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQ 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
           L+A+Y++ T   TPGPA++GRE + P G L  Q +    +G Y LQ   R  Q E    H
Sbjct: 78  LIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHH 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
           ++V+E +AQP++ A+ST + E+   + L C + +     +W FN   L V  R+ LS   
Sbjct: 138 LRVYESVAQPSIQASSTTVTEKGSVV-LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFN 196

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAIL 288
            VL    IR+E+AG YQCEV NPVS +RS+P+ LTV      + IL
Sbjct: 197 HVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLGIL 242



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 3/120 (2%)

Query: 364 SASVVVKLSAAAVATM-IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLS 422
           +AS++   +A   A + I   P +  EG++V L+V   P++L  Y WY+G   EPN+L++
Sbjct: 21  TASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIA 80

Query: 423 QLPSGTWI--AGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
                T +   GPA++GRE   P+  L  Q + L DTG Y L+      + E     L+V
Sbjct: 81  AYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRV 140


>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
           isoform 2 [Homo sapiens]
          Length = 292

 Score =  150 bits (380), Expect = 2e-36
 Identities = 86/218 (39%), Positives = 124/218 (56%), Gaps = 6/218 (2%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ L        A + I   P + +EG+NV L V  L   L +Y WY G T+  + 
Sbjct: 18  LLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQ 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
           L+A+Y++ T   TPGPA++GRE + P G L  Q +    +G Y LQ   R  Q E    H
Sbjct: 78  LIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHH 137

Query: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
           ++V+E +AQP++ A+ST + E+   + L C + +     +W FN   L V  R+ LS   
Sbjct: 138 LRVYESVAQPSIQASSTTVTEKGSVV-LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFN 196

Query: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYF 280
            VL    IR+E+AG YQCEV NPVS +RS+P+ LTV +
Sbjct: 197 HVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 3/120 (2%)

Query: 364 SASVVVKLSAAAVATM-IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLS 422
           +AS++   +A   A + I   P +  EG++V L+V   P++L  Y WY+G   EPN+L++
Sbjct: 21  TASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIA 80

Query: 423 QLPSGTWI--AGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
                T +   GPA++GRE   P+  L  Q + L DTG Y L+      + E     L+V
Sbjct: 81  AYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRV 140


>gi|156564378 carcinoembryonic antigen-related cell adhesion
           molecule 20 5L [Homo sapiens]
          Length = 596

 Score =  144 bits (364), Expect = 1e-34
 Identities = 106/350 (30%), Positives = 167/350 (47%), Gaps = 47/350 (13%)

Query: 86  EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
           E  +  EG ++T +    S    AY+W+         L+ S +          +HT R  
Sbjct: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213

Query: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
                +  I  +   H G Y     N     + +G   V+V E L  P V+ +S  LVE 
Sbjct: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
             ++ L C + + +  V+WF +G  L  +  L LS D R L  HG++R + G Y CEVWN
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 265 PVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWT 324
             S +RSEP+ LT+ +GP++V I ++S +    TI+ + N+SLTL C + S P  EY WT
Sbjct: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388

Query: 325 FNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK--------LSAAAV 376
                 ++  + L I ++T   +G Y C A N+ T L+ S SV+VK        LS+ A+
Sbjct: 389 LEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAI 448

Query: 377 ATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPS 426
           A +++ +           L V     +L  + + R  A  P+R  ++ PS
Sbjct: 449 AGIVIGI-----------LAVIAVASELGYFLYIRN-ARRPSRKTTEDPS 486



 Score =  105 bits (262), Expect = 9e-23
 Identities = 73/297 (24%), Positives = 133/297 (44%), Gaps = 20/297 (6%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           LA+P++  +    +E++D +   C++      + W  N  ++    R+ LS DG++L   
Sbjct: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
            ++RE++G YQCE  + +   RS+PI L V +GP+ V I  +S   +G  ++V   +S+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186

Query: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
               ++S P   Y W      L +      I +++   EG Y C+  N+ T LS   ++ 
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246

Query: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
           V++        +VP      E  + V LT Q   + + V  +  G    P+  L      
Sbjct: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300

Query: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVT--VQGKTETLEVELQVAP 482
                      ++   N +L++  L   DTG Y  +      + ++E LE+ +   P
Sbjct: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGP 346


>gi|156564393 carcinoembryonic antigen-related cell adhesion
           molecule 20 5S [Homo sapiens]
          Length = 584

 Score =  144 bits (364), Expect = 1e-34
 Identities = 106/350 (30%), Positives = 167/350 (47%), Gaps = 47/350 (13%)

Query: 86  EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
           E  +  EG ++T +    S    AY+W+         L+ S +          +HT R  
Sbjct: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213

Query: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
                +  I  +   H G Y     N     + +G   V+V E L  P V+ +S  LVE 
Sbjct: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
             ++ L C + + +  V+WF +G  L  +  L LS D R L  HG++R + G Y CEVWN
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 265 PVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWT 324
             S +RSEP+ LT+ +GP++V I ++S +    TI+ + N+SLTL C + S P  EY WT
Sbjct: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388

Query: 325 FNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK--------LSAAAV 376
                 ++  + L I ++T   +G Y C A N+ T L+ S SV+VK        LS+ A+
Sbjct: 389 LEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAI 448

Query: 377 ATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPS 426
           A +++ +           L V     +L  + + R  A  P+R  ++ PS
Sbjct: 449 AGIVIGI-----------LAVIAVASELGYFLYIRN-ARRPSRKTTEDPS 486



 Score =  105 bits (262), Expect = 9e-23
 Identities = 73/297 (24%), Positives = 133/297 (44%), Gaps = 20/297 (6%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           LA+P++  +    +E++D +   C++      + W  N  ++    R+ LS DG++L   
Sbjct: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
            ++RE++G YQCE  + +   RS+PI L V +GP+ V I  +S   +G  ++V   +S+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186

Query: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
               ++S P   Y W      L +      I +++   EG Y C+  N+ T LS   ++ 
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246

Query: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
           V++        +VP      E  + V LT Q   + + V  +  G    P+  L      
Sbjct: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300

Query: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVT--VQGKTETLEVELQVAP 482
                      ++   N +L++  L   DTG Y  +      + ++E LE+ +   P
Sbjct: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGP 346


>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
           sapiens]
          Length = 426

 Score =  134 bits (336), Expect = 2e-31
 Identities = 99/301 (32%), Positives = 143/301 (47%), Gaps = 24/301 (7%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       AE++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQNLPGYFWYKGEMTDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            + SYIV       GPA++GRE V  + SL IQ +  + +GTY L    R  +T     H
Sbjct: 78  YIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHIIKRGDETREEIRH 137

Query: 183 VQVHEILAQPTVLANSTALVERR--DTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
                 L  P    +S+ L  R   + +RL+C   +  A   W+ NG +LPV  RL LS 
Sbjct: 138 FTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSK 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG-PERVAILQDSTTRTGCTI 299
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +    P     + +   R    +
Sbjct: 198 TNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDV 257

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYT 351
                  L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y 
Sbjct: 258 -------LAFTCEPKS-ENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQ 309

Query: 352 C 352
           C
Sbjct: 310 C 310



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 59/182 (32%), Positives = 84/182 (46%), Gaps = 10/182 (5%)

Query: 192 PTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIR 251
           P +  N+    E +D L   C   S      W+ NG +LPV+  +    + R+L    + 
Sbjct: 242 PYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVT 301

Query: 252 REEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSLTLW 310
           R E G YQCE+ +     RS P+ L V +GP+   I    T  R+G         +L L 
Sbjct: 302 RNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSG--------ENLDLS 353

Query: 311 CVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK 370
           C + S P  EY WT NG+  ++GQ  L I  +T    G Y C   N+ T    S S+ VK
Sbjct: 354 CFTESNPPAEYFWTINGKFQQSGQ-KLFIPQITRNHSGLYACSVHNSATGKEISKSMTVK 412

Query: 371 LS 372
           +S
Sbjct: 413 VS 414



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 33/84 (39%), Positives = 50/84 (59%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEP-NRLLSQLPSGTWIA-GPAHTGREVG 441
           P K +EG+DV L V   P++L  Y WY+G  ++  + ++S +  G  I  GPA++GRE  
Sbjct: 42  PPKVSEGKDVLLLVHNLPQNLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETV 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  +
Sbjct: 102 YSNASLLIQNVTRKDAGTYTLHII 125


>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
           sapiens]
          Length = 428

 Score =  133 bits (334), Expect = 4e-31
 Identities = 97/309 (31%), Positives = 144/309 (46%), Gaps = 22/309 (7%)

Query: 55  LRWSFMALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYA 114
           + W  + LT    LLL+   L   A+++I  EP + S+G +V L+VH L   L  Y WY 
Sbjct: 13  ITWKGLLLTA---LLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQNLAGYIWYK 69

Query: 115 GPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQL 174
           G    + + + SY+V       GPA++GRE V  + SL IQ +    +G+Y L    R  
Sbjct: 70  GQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIVKRGD 129

Query: 175 QTEVGYGHVQVHEILAQPTVLANSTALVERRD--TLRLMCSSPSPTAEVRWFFNGGALPV 232
            T    GH      L  P    +S+ L  R D   + L C   +P A   W+ NG +LP+
Sbjct: 130 GTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPM 189

Query: 233 ALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG-PERVAILQDS 291
              L LS + R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +    P+    + + 
Sbjct: 190 THSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNL 249

Query: 292 TTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMT 343
             R    +       L   C  +S     Y+W  NGQ+L      K   ++  L + S+T
Sbjct: 250 NPRENKDV-------LAFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT 301

Query: 344 AAQEGTYTC 352
             + G Y C
Sbjct: 302 RNETGPYQC 310



 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 60/185 (32%), Positives = 86/185 (46%), Gaps = 8/185 (4%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           L +P +  N+    E +D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 239 LPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILP 298

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
            + R E G YQCE+ +     RS P+ L V +GP+   I    T             +L 
Sbjct: 299 SVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFT-------YYHSGENLY 351

Query: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
           L C + S P  EY WT NG+   +GQ  L I  +T    G Y C  +N+ T +  S S+ 
Sbjct: 352 LSCFADSNPPAEYSWTINGKFQLSGQ-KLFIPQITTKHSGLYACSVRNSATGMESSKSMT 410

Query: 369 VKLSA 373
           VK+SA
Sbjct: 411 VKVSA 415



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTGREVG 441
           PTK ++G+DV L V   P++L  Y WY+G   +    ++   +     I GPA++GRE  
Sbjct: 42  PTKVSKGKDVLLLVHNLPQNLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETV 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  V
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIV 125


>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
           [Homo sapiens]
          Length = 419

 Score =  132 bits (333), Expect = 5e-31
 Identities = 113/416 (27%), Positives = 189/416 (45%), Gaps = 36/416 (8%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           +LL+A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  VLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            + SY+V       GPA++GRE V  + SL IQ +    +G+Y L    R+  T    GH
Sbjct: 78  YITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGH 137

Query: 183 VQ--VHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               +H    +P++ +++    E  + + L C   +P A  +W+ NG +LP+  RL LS 
Sbjct: 138 FTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSK 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +     +  I  ++         
Sbjct: 198 TNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLSKPYITINNLNPR----- 252

Query: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYTC 352
            +    LT  C  +S     Y+W  NGQ+L      K   ++  L + ++T  + G Y C
Sbjct: 253 -ENKDVLTFTCEPKS-KNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQC 310

Query: 353 IAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRG 412
             ++    +  S  V + +        I P  T    G+++ L+          Y+W   
Sbjct: 311 EIRDRYGGIR-SDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTIN 369

Query: 413 PASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQ 468
              +         SG  ++ P  T +  G   CS     +  + TG+ + K++TV+
Sbjct: 370 GKFQ--------LSGQKLSIPQITTKHSGLYACS-----VRNSATGKESSKSITVK 412


>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
           sapiens]
          Length = 435

 Score =  132 bits (332), Expect = 7e-31
 Identities = 96/300 (32%), Positives = 146/300 (48%), Gaps = 23/300 (7%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       A++ I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180
            + SY+V  G    GPA++GRE V  + SL IQ +    +G+Y L    R   T    GY
Sbjct: 78  YITSYVVH-GQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGY 136

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
             V ++    +P++ +++    E  + +RL+C   +P A   W  NG  LP+  RL LS 
Sbjct: 137 FTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSK 196

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +     ++ +   +        K
Sbjct: 197 TNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL---PKLPMPYITINNLNPREK 253

Query: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYTC 352
            D    L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y C
Sbjct: 254 KDV---LAFTCEPKS-RNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQC 309



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 62/188 (32%), Positives = 89/188 (47%), Gaps = 10/188 (5%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           L  P +  N+    E++D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 238 LPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILP 297

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSL 307
            + R E G YQCE+ +     RS P+ L V +GP+   I    T  R+G         +L
Sbjct: 298 SVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSG--------ENL 349

Query: 308 TLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASV 367
            L C + S P  EY WT NG+   +GQ  L I  +T    G Y C  +N+ T    S S+
Sbjct: 350 DLSCFADSNPPAEYSWTINGKFQLSGQ-KLFIPQITTNHSGLYACSVRNSATGKEISKSM 408

Query: 368 VVKLSAAA 375
           +VK+S  A
Sbjct: 409 IVKVSETA 416



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 1/83 (1%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEP-NRLLSQLPSGTWIAGPAHTGREVGF 442
           P K +EG+DV L V   P++L  Y WY+G  ++  + + S +  G  I GPA++GRE  +
Sbjct: 42  PPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVY 101

Query: 443 PNCSLLVQKLNLTDTGRYTLKTV 465
            N SLL+Q +   D G YTL  +
Sbjct: 102 SNASLLIQNVTQEDAGSYTLHII 124


>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
           [Homo sapiens]
          Length = 424

 Score =  132 bits (332), Expect = 7e-31
 Identities = 96/300 (32%), Positives = 146/300 (48%), Gaps = 23/300 (7%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       A++ I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180
            + SY+V  G    GPA++GRE V  + SL IQ +    +G+Y L    R   T    GY
Sbjct: 78  YITSYVVH-GQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGY 136

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
             V ++    +P++ +++    E  + +RL+C   +P A   W  NG  LP+  RL LS 
Sbjct: 137 FTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSK 196

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +     ++ +   +        K
Sbjct: 197 TNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL---PKLPMPYITINNLNPREK 253

Query: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYTC 352
            D    L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y C
Sbjct: 254 KDV---LAFTCEPKS-RNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQC 309



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 61/185 (32%), Positives = 88/185 (47%), Gaps = 10/185 (5%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           L  P +  N+    E++D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 238 LPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILP 297

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSL 307
            + R E G YQCE+ +     RS P+ L V +GP+   I    T  R+G         +L
Sbjct: 298 SVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSG--------ENL 349

Query: 308 TLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASV 367
            L C + S P  EY WT NG+   +GQ  L I  +T    G Y C  +N+ T    S S+
Sbjct: 350 DLSCFADSNPPAEYSWTINGKFQLSGQ-KLFIPQITTNHSGLYACSVRNSATGKEISKSM 408

Query: 368 VVKLS 372
           +VK+S
Sbjct: 409 IVKVS 413



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 1/83 (1%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEP-NRLLSQLPSGTWIAGPAHTGREVGF 442
           P K +EG+DV L V   P++L  Y WY+G  ++  + + S +  G  I GPA++GRE  +
Sbjct: 42  PPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVY 101

Query: 443 PNCSLLVQKLNLTDTGRYTLKTV 465
            N SLL+Q +   D G YTL  +
Sbjct: 102 SNASLLIQNVTQEDAGSYTLHII 124


>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
           7 [Homo sapiens]
          Length = 265

 Score =  129 bits (324), Expect = 6e-30
 Identities = 76/219 (34%), Positives = 111/219 (50%), Gaps = 6/219 (2%)

Query: 68  LLLSA---TFLNV--GAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A   TF N+   A+ +I + P   +EG  V LVVH  S  L  Y+WY G  +  +Y
Sbjct: 18  LLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVHANY 77

Query: 123 LVASYIVSTGDET-PGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYG 181
            +  Y+ +   E  PGPAH GRE + P+G+L IQ +    +G Y L      L  E    
Sbjct: 78  RIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTR 137

Query: 182 HVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPD 241
              V     +P++ +N+   VE +D + L C   +      W+ N  +L V+ RL LS D
Sbjct: 138 QFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTD 197

Query: 242 GRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYF 280
            R L      + + G Y+CE+ NPV  SRS+P+ L V +
Sbjct: 198 NRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRY 236



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 34/91 (37%), Positives = 47/91 (51%), Gaps = 3/91 (3%)

Query: 378 TMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPN-RLLSQLP--SGTWIAGPA 434
           T I  VP    EG++V L V    ++L  Y WY+G     N R++  +   S     GPA
Sbjct: 36  TNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVHANYRIIGYVKNISQENAPGPA 95

Query: 435 HTGREVGFPNCSLLVQKLNLTDTGRYTLKTV 465
           H GRE  +PN +LL+Q +   D G YTL  +
Sbjct: 96  HNGRETIYPNGTLLIQNVTHNDAGFYTLHVI 126


>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
           [Homo sapiens]
          Length = 426

 Score =  128 bits (321), Expect = 1e-29
 Identities = 118/431 (27%), Positives = 186/431 (43%), Gaps = 42/431 (9%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            + SY+V       GPA++GRE +  + SL IQ +    +G+Y L       +     GH
Sbjct: 78  YITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGH 137

Query: 183 VQVHEILAQPTVLANSTALVERR--DTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
                 L  P    +S+ L  R   + + L C   +P A   W+ NG +LP++ RL LS 
Sbjct: 138 FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSE 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG-PERVAILQDSTTRTGCTI 299
             R L   G+ +  AG Y+CE+ NPVS SRS+P  L +    P+    + +   R    +
Sbjct: 198 TNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDV 257

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYT 351
                  L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y 
Sbjct: 258 -------LNFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQ 309

Query: 352 CIAKNTKTLLSGSASVVVKLSAAAVATM--IVPVPTKPTEGQDVTLTVQGYPKDLLVYAW 409
           C     +    G  S  V L+      +  I P  T    G+ + L+          Y+W
Sbjct: 310 C---EIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSW 366

Query: 410 YRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQG 469
                 +         SG  +  P  T +  G   CS     +  + TG+ + K++TV+ 
Sbjct: 367 TINGKFQ--------LSGQKLFIPQITTKHSGLYACS-----VRNSATGKESSKSMTVKV 413

Query: 470 KTETLEVELQV 480
             + + V L +
Sbjct: 414 SGKRIPVSLAI 424


>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
           [Homo sapiens]
          Length = 419

 Score =  127 bits (320), Expect = 2e-29
 Identities = 93/301 (30%), Positives = 141/301 (46%), Gaps = 24/301 (7%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
            + SY+V       GPA++GRE +  + SL IQ +    +G+Y L       +     GH
Sbjct: 78  YITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGH 137

Query: 183 VQVHEILAQPTVLANSTALVERR--DTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
                 L  P    +S+ L  R   + + L C   +P A   W+ NG +LP++ RL LS 
Sbjct: 138 FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSE 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG-PERVAILQDSTTRTGCTI 299
             R L   G+ +  AG Y+CE+ NPVS SRS+P  L +    P+    + +   R    +
Sbjct: 198 TNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDV 257

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYT 351
                  L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y 
Sbjct: 258 -------LNFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQ 309

Query: 352 C 352
           C
Sbjct: 310 C 310



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 60/185 (32%), Positives = 86/185 (46%), Gaps = 10/185 (5%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           L +P +  N+    E +D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 239 LPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILP 298

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSL 307
            + R E G YQCE+ +     RS P+ L V +GP+   I    T  R+G          L
Sbjct: 299 SVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSG--------EVL 350

Query: 308 TLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASV 367
            L C + S P  +Y WT NG+   +GQ  L I  +T    G Y C  +N+ T    S S+
Sbjct: 351 YLSCSADSNPPAQYSWTINGKFQLSGQ-KLFIPQITTKHSGLYACSVRNSATGKESSKSM 409

Query: 368 VVKLS 372
            VK+S
Sbjct: 410 TVKVS 414



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTGREVG 441
           PTK +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA++GRE  
Sbjct: 42  PTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETI 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  +
Sbjct: 102 YSNASLLIQNVTQEDAGSYTLHII 125


>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
           [Homo sapiens]
          Length = 419

 Score =  127 bits (319), Expect = 2e-29
 Identities = 117/423 (27%), Positives = 184/423 (43%), Gaps = 38/423 (8%)

Query: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
           LLL+A+ LN       A+++I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 18  LLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYH 77

Query: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQT--EVGY 180
            V SYIV       GPA++GRE V  + SL IQ +    +G+Y L    R   T    G 
Sbjct: 78  YVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHIIKRGDGTGGVTGR 137

Query: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240
               ++    +P++ +++    E  + + L C   +P A   W+ NG +LP+   L LS 
Sbjct: 138 FTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSE 197

Query: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG-PERVAILQDSTTRTGCTI 299
             R L   G+    AG Y+CE+ NPVS SRS+P+ L +    P+    + +   R    +
Sbjct: 198 TNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDV 257

Query: 300 KVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL--------KNGQDHLNISSMTAAQEGTYT 351
                   T  C  +S     Y+W  NGQ+L        +     L + S+T  + G Y 
Sbjct: 258 S-------TFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQ 309

Query: 352 CIAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYR 411
           C  ++    +  S  V + +        I P  T    GQ++ L+          Y+W  
Sbjct: 310 CEIRDRYGGIR-SDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQYSWTI 368

Query: 412 GPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKT 471
               +         SG  ++ P  T +  G   CS     +  + TG+ + K+VTV+   
Sbjct: 369 NGKFQ--------LSGQKLSIPQITTKHSGLYACS-----VRNSATGKESSKSVTVRVSD 415

Query: 472 ETL 474
            TL
Sbjct: 416 WTL 418


>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
          Length = 426

 Score =  126 bits (317), Expect = 4e-29
 Identities = 94/320 (29%), Positives = 147/320 (45%), Gaps = 22/320 (6%)

Query: 44  GTMSRAYTFFFLRWSFMALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGL 103
           GT+S       ++W  + LT     LL+   L   A+++I  EP + SEG +V L+VH L
Sbjct: 2   GTLSAPPCTQRIKWKGLLLTAS---LLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNL 58

Query: 104 SGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSG 163
              L  Y WY G    + + + SY+V       GPA++GRE    + SL IQ +    +G
Sbjct: 59  PQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAG 118

Query: 164 TYILQTFNRQLQTE--VGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEV 221
           +Y L        T    G     +H    +P++ +++    E  + + L C   +P A  
Sbjct: 119 SYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASY 178

Query: 222 RWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFG 281
            W+ NG +LP+   L LS   R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +   
Sbjct: 179 LWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPK 238

Query: 282 -PERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQ 334
            P+    + +   R    +       L   C  +S     Y+W  NGQ+L      K   
Sbjct: 239 LPKPYITINNLNPRENKDV-------LNFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPI 290

Query: 335 DH--LNISSMTAAQEGTYTC 352
           ++  L + S+T  + G Y C
Sbjct: 291 ENRILILPSVTRNETGPYQC 310



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 58/185 (31%), Positives = 85/185 (45%), Gaps = 10/185 (5%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           L +P +  N+    E +D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 239 LPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILP 298

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSL 307
            + R E G YQCE+ +     RS+P+ L V +GP+   I    T  R+G          L
Sbjct: 299 SVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSG--------EVL 350

Query: 308 TLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASV 367
            L C + S P  +Y WT N +    GQ  L I  +T    G Y C  +N+ T    S S+
Sbjct: 351 YLSCSADSNPPAQYSWTINEKFQLPGQ-KLFIRHITTKHSGLYVCSVRNSATGKESSKSM 409

Query: 368 VVKLS 372
            V++S
Sbjct: 410 TVEVS 414



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)

Query: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQ--LPSGTWIAGPAHTGREVG 441
           PTK +EG+DV L V   P++L  Y WY+G   +    ++   +     I GPA++GRE  
Sbjct: 42  PTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETA 101

Query: 442 FPNCSLLVQKLNLTDTGRYTLKTV 465
           + N SLL+Q +   D G YTL  +
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHII 125


>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  105 bits (262), Expect = 9e-23
 Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 8/183 (4%)

Query: 191 QPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGI 250
           +P++ +++    E  +T+ L C+  +P A   W+ NG +LP+  R+ LS   R L   G+
Sbjct: 26  KPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGV 85

Query: 251 RREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLW 310
            +  AG Y+CE+WN  S SRS+P+ L +  GP+   I    T+            +L L 
Sbjct: 86  TKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYS-------GENLDLS 138

Query: 311 CVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK 370
           C + S P  +Y WT NG+   +GQ  L I  +T    G Y C A+N+ T    S S+ ++
Sbjct: 139 CFANSNPPAQYSWTINGKFQLSGQ-KLFIPQITPKHNGLYACSARNSATGEESSTSLTIR 197

Query: 371 LSA 373
           + A
Sbjct: 198 VIA 200


>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  105 bits (262), Expect = 9e-23
 Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 8/183 (4%)

Query: 191 QPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGI 250
           +P++ +++    E  +T+ L C+  +P A   W+ NG +LP+  R+ LS   R L   G+
Sbjct: 26  KPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGV 85

Query: 251 RREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLW 310
            +  AG Y+CE+WN  S SRS+P+ L +  GP+   I    T+            +L L 
Sbjct: 86  TKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYS-------GENLDLS 138

Query: 311 CVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK 370
           C + S P  +Y WT NG+   +GQ  L I  +T    G Y C A+N+ T    S S+ ++
Sbjct: 139 CFANSNPPAQYSWTINGKFQLSGQ-KLFIPQITPKHNGLYACSARNSATGEESSTSLTIR 197

Query: 371 LSA 373
           + A
Sbjct: 198 VIA 200


>gi|122937205 carcinoembryonic antigen-related cell adhesion
           molecule 18 [Homo sapiens]
          Length = 398

 Score =  104 bits (260), Expect = 2e-22
 Identities = 80/307 (26%), Positives = 139/307 (45%), Gaps = 9/307 (2%)

Query: 56  RWSFMALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAG 115
           RWS          LL+        +I IT       +G    + +  +  ++  YSWY G
Sbjct: 68  RWSLWRRVFLMASLLACGICQASGQIFIT--QTLGIKGYRTVVALDKVPEDVQEYSWYWG 125

Query: 116 PTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQ 175
              S   ++ S+   +  + PGP +TGRE V  +GSL I+      +G Y ++      +
Sbjct: 126 ANDSAGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-E 183

Query: 176 TEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALR 235
           T+   G ++V E+ +   +  N+++LVE  D++   C +      + W+ N      + R
Sbjct: 184 TQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTN--VTNITWYVNDVPTSSSDR 241

Query: 236 LGLSPDGRVLARHGIRREEAGAYQCEVWN-PVSVSRSEPINLTVYFGPERVAILQDSTTR 294
           + +SPDG+ L    + R +    QC + + P    RSE I+LTV +GP+ V +  +    
Sbjct: 242 MTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300

Query: 295 TGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIA 354
            G  +  +  + + + C+  S  + +Y W  NG  L      +N+SS+   Q G Y C  
Sbjct: 301 NGI-VTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTV 359

Query: 355 KNTKTLL 361
           +N  T L
Sbjct: 360 ENPVTQL 366



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 11/101 (10%)

Query: 394 TLTVQGY---------PKDLLVYAWYRGP-ASEPNRLLSQLPSGTWIAGPAHTGREVGFP 443
           TL ++GY         P+D+  Y+WY G   S  N ++S  P      GP +TGRE    
Sbjct: 98  TLGIKGYRTVVALDKVPEDVQEYSWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNR 157

Query: 444 NCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG 484
             SLL++   L DTG YT++ V    +T+     L+V  LG
Sbjct: 158 EGSLLIRPTALNDTGNYTVR-VVAGNETQRATGWLEVLELG 197


>gi|156564390 carcinoembryonic antigen-related cell adhesion
           molecule 20 4L [Homo sapiens]
          Length = 503

 Score =  103 bits (258), Expect = 3e-22
 Identities = 71/293 (24%), Positives = 130/293 (44%), Gaps = 18/293 (6%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           LA+P++  +    +E++D +   C++      + W  N  ++    R+ LS DG++L   
Sbjct: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
            ++RE++G YQCE  + +   RS+PI L V +GP+ V I  +S   +G  ++V   +S+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186

Query: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
               ++S P   Y W      L +      I +++   EG Y C+  N+ T LS   ++ 
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246

Query: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
           V++        +VP      E  + V LT Q   + + V  +  G    P+  L      
Sbjct: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300

Query: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
                      ++   N +L++  L   DTG Y  +      +  +  +EL +
Sbjct: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 27/194 (13%)

Query: 86  EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
           E  +  EG ++T +    S    AY+W+         L+ S +          +HT R  
Sbjct: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213

Query: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
                +  I  +   H G Y     N     + +G   V+V E L  P V+ +S  LVE 
Sbjct: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
             ++ L C + + +  V+WF +G  L  +  L LS D R L  HG++R + G Y CEVWN
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 265 PVSVSRSEPINLTV 278
             S +RSEP+ LT+
Sbjct: 329 WGSRARSEPLELTI 342


>gi|156564388 carcinoembryonic antigen-related cell adhesion
           molecule 20 4S [Homo sapiens]
          Length = 491

 Score =  103 bits (258), Expect = 3e-22
 Identities = 71/293 (24%), Positives = 130/293 (44%), Gaps = 18/293 (6%)

Query: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
           LA+P++  +    +E++D +   C++      + W  N  ++    R+ LS DG++L   
Sbjct: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126

Query: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
            ++RE++G YQCE  + +   RS+PI L V +GP+ V I  +S   +G  ++V   +S+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186

Query: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
               ++S P   Y W      L +      I +++   EG Y C+  N+ T LS   ++ 
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246

Query: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
           V++        +VP      E  + V LT Q   + + V  +  G    P+  L      
Sbjct: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300

Query: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
                      ++   N +L++  L   DTG Y  +      +  +  +EL +
Sbjct: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 27/194 (13%)

Query: 86  EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
           E  +  EG ++T +    S    AY+W+         L+ S +          +HT R  
Sbjct: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213

Query: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
                +  I  +   H G Y     N     + +G   V+V E L  P V+ +S  LVE 
Sbjct: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
             ++ L C + + +  V+WF +G  L  +  L LS D R L  HG++R + G Y CEVWN
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 265 PVSVSRSEPINLTV 278
             S +RSEP+ LT+
Sbjct: 329 WGSRARSEPLELTI 342


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,210,123
Number of Sequences: 37866
Number of extensions: 895496
Number of successful extensions: 3964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 193
Number of HSP's that attempted gapping in prelim test: 2320
Number of HSP's gapped (non-prelim): 1149
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.