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Search of human proteins with 7661958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661958 BCL2-associated transcription factor 1 isoform 1
[Homo sapiens]
(920 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 1857 0.0
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 1670 0.0
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 1644 0.0
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 1633 0.0
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 838 0.0
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 533 e-151
gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 104 3e-22
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 103 6e-22
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 96 1e-19
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 94 8e-19
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 89 2e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 89 2e-17
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 89 2e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 86 2e-16
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 86 2e-16
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 84 6e-16
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 81 4e-15
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 81 5e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 80 9e-15
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 80 1e-14
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 80 1e-14
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 79 1e-14
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 79 2e-14
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 79 2e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 79 3e-14
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 77 6e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 76 1e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 76 1e-13
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 74 8e-13
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 73 1e-12
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 1857 bits (4811), Expect = 0.0
Identities = 920/920 (100%), Positives = 920/920 (100%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
Query: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
Query: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
Sbjct: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
Query: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
Query: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
Query: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
Query: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840
HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
Sbjct: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840
Query: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900
PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
Sbjct: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900
Query: 901 EEETMENNEEKKDRRKEEKE 920
EEETMENNEEKKDRRKEEKE
Sbjct: 901 EEETMENNEEKKDRRKEEKE 920
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 1670 bits (4325), Expect = 0.0
Identities = 854/928 (92%), Positives = 855/928 (92%), Gaps = 67/928 (7%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 358
Query: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 359 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 418
Query: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
Sbjct: 419 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 478
Query: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
Query: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
Query: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 718
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Query: 781 HEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPKE 832
HEMKEYSGFAGVSRPRGTF R RGR RG F
Sbjct: 779 HEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF-------------------- 818
Query: 833 EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKY 892
+RGR GRFNFKKSGSSPKWTHDKY
Sbjct: 819 ----------------------------QRGR---------GRFNFKKSGSSPKWTHDKY 841
Query: 893 QGDGIVEDEEETMENNEEKKDRRKEEKE 920
QGDGIVEDEEETMENNEEKKDRRKEEKE
Sbjct: 842 QGDGIVEDEEETMENNEEKKDRRKEEKE 869
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 1644 bits (4258), Expect = 0.0
Identities = 844/928 (90%), Positives = 846/928 (91%), Gaps = 67/928 (7%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 358
Query: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 359 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 418
Query: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKE
Sbjct: 419 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKE 478
Query: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
Query: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
Query: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
TSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
TLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GS
Sbjct: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGS 718
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
RKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Query: 781 HEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPKE 832
HEMKEYSGFAGVSRPRGTF R RGR RG F
Sbjct: 779 HEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF-------------------- 818
Query: 833 EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKY 892
+RGR GRFNFKKSGSSPKW HDKY
Sbjct: 819 ----------------------------QRGR---------GRFNFKKSGSSPKWNHDKY 841
Query: 893 QGDGIVEDEEETMENNEEKKDRRKEEKE 920
QGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 842 QGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 1633 bits (4228), Expect = 0.0
Identities = 840/928 (90%), Positives = 842/928 (90%), Gaps = 67/928 (7%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
SKSQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 358
Query: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 359 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 418
Query: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKE
Sbjct: 419 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKE 478
Query: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
Query: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
Query: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
TSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
TLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GS
Sbjct: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGS 718
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
RKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Query: 781 HEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPKE 832
HEMKEYSGFAGVSRPRGTF R RGR RG F
Sbjct: 779 HEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF-------------------- 818
Query: 833 EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKY 892
+RGR GRFNFKKSGSSPKW HDKY
Sbjct: 819 ----------------------------QRGR---------GRFNFKKSGSSPKWNHDKY 841
Query: 893 QGDGIVEDEEETMENNEEKKDRRKEEKE 920
QGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 842 QGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 838 bits (2165), Expect = 0.0
Identities = 467/740 (63%), Positives = 515/740 (69%), Gaps = 61/740 (8%)
Query: 237 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 272
S+S S S + S HS K S S S +S RS
Sbjct: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
Query: 273 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 320
G G G RY P+ + RSP + + +P R SR R S
Sbjct: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
Query: 321 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 373
+ + ++ KR +E + + G +++ K K E+ +
Sbjct: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
Query: 374 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 426
E + E++D F+ + G +++S + +S +T
Sbjct: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
Query: 427 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
S +NT + +++ + S G+ S + +N + T ++
Sbjct: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311
Query: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
Query: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
Query: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
Query: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840
HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
Sbjct: 608 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 667
Query: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900
PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
Sbjct: 668 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 727
Query: 901 EEETMENNEEKKDRRKEEKE 920
EEETMENNEEKKDRRKEEKE
Sbjct: 728 EEETMENNEEKKDRRKEEKE 747
Score = 686 bits (1769), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
Score = 38.1 bits (87), Expect = 0.038
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 737 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 787
+ +S+ + SRS SSS S S SR+++ S + R + + ++Y
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
Query: 788 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 845
G+ RP G RGR RG + G + + W+ + +P+ +
Sbjct: 63 NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109
Query: 846 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 903
+ V R R R +++ R + SSP K K +G + ++
Sbjct: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
Query: 904 TMENNEEKKDRRKEEKE 920
E EE + K ++E
Sbjct: 170 EGEPQEESPLKSKSQEE 186
Score = 38.1 bits (87), Expect = 0.038
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
+ +S+ + SRS SSS S S SR+++ S + R + + ++Y
Sbjct: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 614
Query: 63 NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109
G+ RP G RGR RG + G + + W+ + +P+ +
Sbjct: 615 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 672
Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
+ V R R R +++ R + SSP K K +G + ++
Sbjct: 673 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 730
Query: 170 EGEPQEESPLKSKSQEE 186
E EE + K ++E
Sbjct: 731 TMENNEEKKDRRKEEKE 747
Score = 33.1 bits (74), Expect = 1.2
Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%)
Query: 633 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 691
+S K+ + S+R +S R+ S S R ++R +R++ + ++ + R
Sbjct: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65
Query: 692 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 737
+R R + R +G + + SR R + ++PK + S +
Sbjct: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124
Query: 738 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 794
S+ +R SRS SS+S SS + SK+ +E +T E +E S S+
Sbjct: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
Query: 795 --PRGTF 799
P+ TF
Sbjct: 185 EEPKDTF 191
Score = 33.1 bits (74), Expect = 1.2
Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%)
Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65
+S K+ + S+R +S R+ S S R ++R +R++ + ++ + R
Sbjct: 460 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 518
Query: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124
+R R + R +G + + SR R + ++PK + S +
Sbjct: 519 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 564
Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
S+ +R SRS SS+S SS + SK+ +E +T E +E S S+
Sbjct: 565 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 621
Query: 185 EEPKDTF 191
P+ TF
Sbjct: 622 --PRGTF 626
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 533 bits (1373), Expect = e-151
Identities = 399/972 (41%), Positives = 537/972 (55%), Gaps = 96/972 (9%)
Query: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
G +SRS S SRS+SRS S SRSRSRS SRK+R SSRSRSR+YS + +R+R + R Y+
Sbjct: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
Query: 59 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 112
RD+R +NRG RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
Query: 113 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
Query: 171 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224
P + + ++ E + TF + SES + ++ +G + + SPR
Sbjct: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
Query: 225 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 280
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
Query: 281 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 340
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
Query: 341 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 398
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
Query: 399 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 453
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
Query: 454 REEKNYKLKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 499
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
Query: 500 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 558
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
Query: 559 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 618
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
Query: 619 QYFKSAAMTLNERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFK 676
+F S+ MTL+ERFT Y K +E + +KSPEIHRRIDISPST RKH E + +
Sbjct: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
Query: 677 EENQKGDKKLRCDSADLRHDIDRRRK--ERSKERGDSK---GSRESSGSRKQ--EKTPKD 729
E K + K + D DLR DI+RR+K ER +RG S+ SR+SS SR++ EKT K
Sbjct: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
Query: 730 YKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----K 784
+K K K KH+R +D SRSSSSS+ S EE + E EE T + K
Sbjct: 761 HKGSKKQK---KHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
Query: 785 EYSGFA--GVSRPRGTF-FRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTP 841
++ G + G R RGTF FR RGRG RG ++G N NNSN FQKR +EEEWDPEYTP
Sbjct: 818 DFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWDPEYTP 875
Query: 842 KSKKYFLHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVE 899
KSKKY+LHDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +E
Sbjct: 876 KSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIE 935
Query: 900 DEEETMENNEEK 911
D+E EN EEK
Sbjct: 936 DDESGTENREEK 947
>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
Length = 682
Score = 104 bits (260), Expect = 3e-22
Identities = 110/448 (24%), Positives = 193/448 (43%), Gaps = 55/448 (12%)
Query: 326 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 383
G ++ F KR+ ++ G+T R K+ + + E R +W+ + +L
Sbjct: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
Query: 384 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 432
+ + G Q + +E + E + DYR R +L D + F+ + + +
Sbjct: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
Query: 433 EEGLKYKSKVSLKG--NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITV 490
EE KY + KG NRE D F + + ++ K+ K K+S T
Sbjct: 306 EEDRKYSFQ---KGPLNRELDCFNTGRGRETQD--------GQVKEPFKPSKKDSIACTY 354
Query: 491 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 550
+ + ++K K+ K ++ + + +K + + + +K
Sbjct: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
Query: 551 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 607
+ D+ R AS + +R ++ LV +K + F +F+H+ Q +K T E F Q
Sbjct: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
Query: 608 HIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 664
I++++H VK YF S +TL+ERF++ Q KA PEIHRRID+S + L+
Sbjct: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
Query: 665 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---------SKGSR 715
++ V E Q K + D DLRHDI+RRRKER + + + +
Sbjct: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
Query: 716 ESSGSRKQEKTPKDYKEYKSYKDDSKHK 743
SS S+ KD +K ++ + H+
Sbjct: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHR 613
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 103 bits (258), Expect = 6e-22
Identities = 118/352 (33%), Positives = 153/352 (43%), Gaps = 55/352 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSR-SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR----D 56
GRS+SRS ++R +SRS++ +R RSRS + +R RSRSRT +R RSR R +R
Sbjct: 560 GRSHSRSPATRGRSRSRTPARRGRSRSRTPARR---RSRSRTPTRRRSRSRTPARRGRSR 616
Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSP 115
R R R P R R R + G R R R SR+P RRGRSRSR+P
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTP 674
Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175
RRS S RSR+ +RR SR+PR SRS S RRG +T + G
Sbjct: 675 ARRSGRS-RSRTPARRGRSRSRTPRRGRSRSRS-------LVRRGRSHSRTPQRRGRSGS 726
Query: 176 ESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP--------- 226
S K+KS+ + S S E KS +S S +SPRS
Sbjct: 727 SSERKNKSRTSQR----RSRSNSSPEMKKSRISS-----RRSRSLSSPRSKAKSRLSLRR 777
Query: 227 ----HSPSP---IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
SP P TPP +S S S P + TP + S S P + S +
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQP-----KAKSRTPPRRSRSSSSPPPKQKSKT--- 829
Query: 280 GSSRYSPSQNSPIHHIPSRRSP--AKTIAPQNAPRDESRGRSSFYPDGGDQE 329
SR S S +SP + S P +PQ + + R S + D E
Sbjct: 830 -PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Score = 102 bits (254), Expect = 2e-21
Identities = 110/359 (30%), Positives = 144/359 (40%), Gaps = 54/359 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
GRS SR+ + R +SRS++ +R RS SR RSRSRT R RSR R R
Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVR------ 709
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNR-RHSRSPRRGRSRSRSPKRRSV 120
RG + RGR G + R R R + SP +SR S + RS+
Sbjct: 710 ---RGRSHSRTPQRRGRS----GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762
Query: 121 SSQRSRSRSRRSYRSSRS-------------PRSSSSRSSSPYSKS--PVSKRRGSQEKQ 165
SS RS+++SR S R S S PR S S SS P +KS P + R S
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP 822
Query: 166 TKKAEGEPQEESPLKSKSQEEPKD-TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP- 223
K+ P +S S + K T S + + N+ S T S +++SP
Sbjct: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP----QRRSCFESSPD 878
Query: 224 -----RSPH-------SPSPI--ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269
R+P SP + +TPP QS S S +P HS S SP
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 270 ERSGSGSVGNGSSRYSPSQNSPIHHIP-----SRRSPAKTIAPQNAPRDESRGRSSFYP 323
R S + S SP N +P SP + P+ PR G S YP
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 90.9 bits (224), Expect = 5e-18
Identities = 109/346 (31%), Positives = 141/346 (40%), Gaps = 44/346 (12%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSS---RSRSRT-----YSRSRSRDRMY 53
GRS SR+ + R SRS+S RSRS R R S R RSR+ +SRSR+ R
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-- 550
Query: 54 SRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113
R R R R R RGR R GR P R SR+P R RSRSR
Sbjct: 551 -RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPTRRRSRSR 607
Query: 114 SPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP-----YSKSPVSKRRGSQEKQTKK 168
+P RR S RSR+ +RR R +RSP SRS SP S+S RRG +T
Sbjct: 608 TPARRGRS--RSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664
Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
G + +P + + + S S S + + G S HS
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---------HS 715
Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
+P S SSS K+ SQ SPE S SSR S S
Sbjct: 716 RTPQRRGRSGSSS---------ERKNKSRTSQRRSRSNSSPEMKKS----RISSRRSRSL 762
Query: 289 NSPIHHIPSRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKT 333
+SP SR S ++++ + P+ +S+ G Q AK+
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Score = 86.7 bits (213), Expect = 9e-17
Identities = 104/332 (31%), Positives = 142/332 (42%), Gaps = 31/332 (9%)
Query: 4 SNSRSH--SSRSKSRSQSSSR--SRSRSHSRKKRYSSRSRS---RTYSRSRSRDRMYSRD 56
S +RSH + R KS S + SR RSRS + KR SRSR+ R +SRSRS SR
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 116
+R R+ R RGR R + G R R R SRS RRGRS SRSP
Sbjct: 519 AQRWGRSRSPQR-----RGRSRSPQRPGWSR-----SRNTQRRGRSRSARRGRSHSRSPA 568
Query: 117 RRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP---YSKSPVSKRRGSQEKQTKKAEGEP 173
R S RSR+ +RR SR+P SRS +P S+S RRG +T A
Sbjct: 569 TRGRS--RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT-PARRRS 625
Query: 174 QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
+ SP++ +S+ S S + + S + +P S
Sbjct: 626 RTRSPVRRRSRSR-SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
Query: 234 TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPE---RSGSGSVGNGSSRYSP--SQ 288
TP + S S P S SHS +P+ RSGS S SR S S+
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHS--RTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 289 NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 320
++ + R ++ ++PR +++ R S
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
Score = 71.2 bits (173), Expect = 4e-12
Identities = 103/385 (26%), Positives = 143/385 (37%), Gaps = 59/385 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR------ 55
GRS S +SRS+S + R + SS+S SR RSRSR R+ R
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Query: 56 ----------DYRRDYRNNRG-MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-HSR 103
R R RG R P R R R + R P +RR SR
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879
Query: 104 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163
+P R RSRS + VS +RSRSR+ + R SRS S SR S PV++RR
Sbjct: 1880 TPLISRRRSRS-RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 164 KQT--KKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
T +++ + +S+S+ P S +S + + + S
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 222 SP----RSPHSPSPIA-------TPPS-QSSSCSDAPMLSTVHSAKNTP----------- 258
SP RS SP+ TPP+ + S S P+L S +P
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 259 ---SQHSHSIQHSP----ERSGSGSVGNGSSRYSP--------SQNSPIHHIPSRRSPAK 303
++ S+ SP RS SGS + S +P S+ P+ SR S
Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118
Query: 304 TIAPQNAPRDESRGRSSFYPDGGDQ 328
+ P D R P G +
Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSR 2143
Score = 68.9 bits (167), Expect = 2e-11
Identities = 82/301 (27%), Positives = 122/301 (40%), Gaps = 49/301 (16%)
Query: 19 SSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGR 78
SS S++RSH R KR +S S T SR R R + R R+ +R
Sbjct: 455 SSPTSKNRSHGRAKR--DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR--------- 503
Query: 79 GYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRS 138
G+ + ++ R W R SRSP+R R RSRSP+R S RSR+ RR
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGR--SRSPQR-RGRSRSPQRPGWS--RSRNTQRRG------ 552
Query: 139 PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSES 198
RS S+R +S+SP + RG +T G + +P + +S+ T S S
Sbjct: 553 -RSRSARRGRSHSRSPAT--RGRSRSRTPARRGRSRSRTPARRRSRSR---TPTRRRSRS 606
Query: 199 IDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTP 258
+ + S R+P P + S S +P + S TP
Sbjct: 607 RTPARRGRSRS--------------RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP 652
Query: 259 SQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGR 318
++ S +P R G + R S++ P+RR +++ P+ R SR R
Sbjct: 653 ARRGRSRSRTPARRGRSRSRTPARRSGRSRS----RTPARRGRSRSRTPR---RGRSRSR 705
Query: 319 S 319
S
Sbjct: 706 S 706
Score = 64.7 bits (156), Expect = 4e-10
Identities = 160/790 (20%), Positives = 281/790 (35%), Gaps = 126/790 (15%)
Query: 16 RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRG 75
R SSSRS + +KK+ R R R+ S S R+R S ++ + +R
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGR-RSESSSPRRERKKSSKKKKHRSESESKKRK----- 228
Query: 76 RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 135
HR ++R S+ +R RSRS +P +SRR++RS
Sbjct: 229 -------------HRSPTPK--SKRKSKDKKRKRSRSTTP----------APKSRRAHRS 263
Query: 136 SRSPRSSSSRSSSPYSKSPVSKR-------RGSQEKQTKKAEGE-PQEESPLKSKSQEEP 187
+ + +SSS +S S+S +K R ++ EG+ P E S +
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323
Query: 188 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP-PSQSSSCSDAP 246
+T PS ++ +K P S + S P P+P TP ++ S P
Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSP-ERSSTGPEPPAP--TPLLAERHGGSPQP 380
Query: 247 MLSTVHSAK--NTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKT 304
+ +T S + N PS+ S + SP +S + SS SP P SR + +
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK--VSRHASSSP 438
Query: 305 IAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV------FLLDRGNTRDK 358
+P+ AP S S P ++ + + R+ RG +R +
Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498
Query: 359 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFND--------SEGDDTEETEDYRQ 410
+K +G + R+ +W + + S +++ S +T+ R
Sbjct: 499 TPTK-RGHSRSRSP-QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 411 FRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVER 470
R+ +S AT + + +S+ R S R + + R
Sbjct: 557 ARRG--RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS---RSRTPTRRRSRSRTPAR 611
Query: 471 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 530
++ + ++ R V++ ++S SP AR R
Sbjct: 612 RGRSRSRTPARRRSRTRSPVRRRSRS--------------RSP-------ARRSGRSRSR 650
Query: 531 SPLRIKMIASDSHRPEVK-LKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 589
+P R S S P + + P S R S T R S + RS+
Sbjct: 651 TPAR--RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
Query: 590 ----DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 645
H + PQ + S E+ KS R S + + +
Sbjct: 709 RRGRSHSRTPQRRGRSGSS------------SERKNKSRTSQRRSRSNSSPEMKKSRISS 756
Query: 646 QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 705
++S + + S L L+G K+++Q ++ R S+ + ++
Sbjct: 757 RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS----------QPKA 806
Query: 706 KERGDSKGSRESSG--SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSS 763
K R + SR SS +++ KTP +S+ S H + + S + S +SP +
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTP----SRQSHSSSSPHPKVK--SGTPPRQGSITSPQA 860
Query: 764 REEKESKKER 773
E+ + + R
Sbjct: 861 NEQSVTPQRR 870
Score = 64.3 bits (155), Expect = 5e-10
Identities = 99/361 (27%), Positives = 138/361 (38%), Gaps = 72/361 (19%)
Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
R+ + S RS S + + RSRSRS K R + R S+S SR R SR R
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVT 1811
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
R RG G GY+ R R SR+P R RSRS R+
Sbjct: 1812 RRRRG----------GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS---RTSP 1858
Query: 122 SQRSRSRSRRS---YRSSRSPRSSSSRSSSPYSKSPVSKRRG-SQEKQTKKAEGEPQEES 177
+ RSRSR S +R SRS SR S SPVS+RR S+ T++
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRR--------- 1909
Query: 178 PLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 237
+S+S+ P + S T P S TP +
Sbjct: 1910 --RSRSRASP-----------VSRRRSRSRT--------------PPVTRRRSRSRTPTT 1942
Query: 238 QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 297
+ S S P ++ S TP + RS + + + R S S+ SP +
Sbjct: 1943 RRRSRSRTPPVTRRRSRSRTP-----PVTRRRSRSRTSPI---TRRRSRSRTSP---VTR 1991
Query: 298 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 357
RRS ++T +P R RS P + ++T ++R SR LL R +R
Sbjct: 1992 RRSRSRT-----SPVTRRRSRSRTSPVTRRRSRSRTPPAIRR--RSRSRTPLLPRKRSRS 2044
Query: 358 K 358
+
Sbjct: 2045 R 2045
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 18/210 (8%)
Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA- 169
RS S S SS S S S S SS S S S SS P KR S K+A
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 170 -EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
EG P E +P K K + + S S + SS++S S+ +S S S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 229 P------------SPIATPPSQSSSCSDAPMLSTVHSAKNTP----SQHSHSIQHSPERS 272
P SP PP + S S + ++ +++ + S Q SP
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 273 GSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 302
S S GS R + H R +P+
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Score = 53.5 bits (127), Expect = 9e-07
Identities = 154/761 (20%), Positives = 264/761 (34%), Gaps = 124/761 (16%)
Query: 98 NRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 157
++ HS +P R RSRSP RSR+ ++R + SRSP+ SRS+ + +S +
Sbjct: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ 529
Query: 158 RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 217
RRG PQ +S++ + + S ++S AT G
Sbjct: 530 RRGRSR--------SPQRPGWSRSRNTQRRGRSRSARRGRS---HSRSPATRGRSRSRTP 578
Query: 218 AYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--- 274
A RS P++ S S P + S TP++ S +P R S
Sbjct: 579 ARRGRSRS--------RTPARRRSRSRTP--TRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 275 GSVGNGSSRYSPSQNS--PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAK 332
V S SP++ S P+RR +++ P R SR + + A+
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 333 TGKFL----KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE 388
G+ +R + R ++R + GS R Q S E
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 389 SGKQKFNDSEGDDTEETEDYRQFRKSVL--------ADQGKSFATASHRNTEEEGLKYKS 440
K + + + R S+ + KS + K KS
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Query: 441 KVSLKGNRESDGFREEKNYKLK--------------ETGYVVERPSTTKDKHKEEDKNSE 486
+ + +R S ++ K ++G + S T + E+ +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
Query: 487 RITVKKETQSPE-QVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL-RIKMIASDSHR 544
R + + + PE + ++ SPP K+ +S R SP ++K I S R
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
Query: 545 PEVKLKMAPVPLDDSNR----------PASLTKDRLL-------ASTLVHSVKKEQEFR- 586
+P P ++R P S + RLL +S+ VK E R
Sbjct: 929 SH-SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQ 987
Query: 587 ----SIFDHIKL---------------PQASKSTSESFIQHI---VSLVHHVK------E 618
SI + K+ P + + +S +Q +SL VK E
Sbjct: 988 SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGE 1047
Query: 619 QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEE 678
YF +++ L + + +H + SPE+ + SPS + +
Sbjct: 1048 SYFGVSSLQLK----GQSQTSPDHRSDTSSPEVRQSHSESPS--------------LQSK 1089
Query: 679 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGS--RESSGSRKQEKTPKDYKEYKSY 736
+Q K R S+ ++ R R ++RG+ S +S S +Q + D Y +
Sbjct: 1090 SQTSPKGGRSRSSSPVTELASRSPIR-QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148
Query: 737 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEF 777
DS Q ++ S + P + S ++++F
Sbjct: 1149 --DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Score = 53.5 bits (127), Expect = 9e-07
Identities = 102/392 (26%), Positives = 147/392 (37%), Gaps = 55/392 (14%)
Query: 3 RSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
RS S S S R S SSS S H K R ++R SR+ +++ R R RR
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR-TARRGSRSSPEPKTKSRTPPR--RRSS 1691
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR-SV 120
R++ + R R R R P R S S +SRS +RR S
Sbjct: 1692 RSSPELTRKARLSRRSRS---ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 121 SSQRSRSRSRRSYRSSRSPRS-SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
SS R+++ SRR S PR SRS S K+ ++RR G Q S
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR--------DRSGSSQSTSRR 1800
Query: 180 KSKSQEEPKDTFE-------HDPSESIDEFNKSSATSGDIWPGLS----AYDNSPRSPHS 228
+ +S+ + T H S + E SS TS G S RS S
Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQE---SSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857
Query: 229 PSP------IATPPSQSSSCSDAPMLSTVHSAKNTP------SQHSHSIQHSPERSGSGS 276
P+P A+P + S S P++S S T S+ S+ RS +
Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917
Query: 277 VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKF 336
V S R S S+ P + RRS ++T P R RS P + ++T
Sbjct: 1918 V---SRRRSRSRTPP---VTRRRSRSRT------PTTRRRSRSRTPPVTRRRSRSRTPPV 1965
Query: 337 LKRFTDEESRVFLLDRGNTRDKEASKEKGSEK 368
+R + + R +R ++ + +
Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
Score = 49.7 bits (117), Expect = 1e-05
Identities = 92/343 (26%), Positives = 128/343 (37%), Gaps = 53/343 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS-SRSRSRTYSRSRSRDRMYSRDYRRDY 61
RS+ S S S + + S ++S S + R+ SR S S S M R
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSR-SRSPKRR 118
R +R G G G G R+ G P + R+P RGRS SP+ +
Sbjct: 1437 RRSRS--------GSSPGLRDGSGTPSRHSLSGSSPGM-KDIPRTPSRGRSECDSSPEPK 1487
Query: 119 SV-SSQRSRSRSRRSYRSSR---SPRSSSSRSSSPYSKSPVSK-------RRGSQEKQTK 167
++ + R RSRS S + +P+ S S S + V++ R GS ++
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 168 KAEGEPQEESPLKSKSQEEPKDTF---EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224
K PQE S S + K + S S E + S S P S +SP
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS----PRRSRSGSSPE 1603
Query: 225 SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG---S 281
P A P +QS S S +P + + + P RS SGS G S
Sbjct: 1604 VKDKPR--AAPRAQSGSDS-------------SPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Query: 282 SRYSPSQNSPIHHIP----SRRSPAKTIAPQNAPRDESRGRSS 320
S S S H P +RR + P+ R R RSS
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 23/231 (9%)
Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
P + + SPR S R+ R+RSR + R +S R+ SP
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP----- 2427
Query: 155 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK----DTFEHDPSESIDEFNKSSATS- 209
S R G Q+ + Q SP+ S ++ + T S+S+ ++ TS
Sbjct: 2428 -SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
Query: 210 -GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268
GD LS +P PH S + PP+ S+ L+ + AK S S S S
Sbjct: 2487 AGDHNGMLSV--PAPGVPH--SDVGEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 269 PERSGSGSVGNGSSRYSPSQNSPIHHIP------SRRSPAKTIAPQNAPRD 313
S S S + SS S S +S +P +R P+ T AP+ A R+
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 16/214 (7%)
Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP- 173
P + + Q S + + + RS SSSS SSS S S S S + +EG
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 174 --QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
Q E LK P P E++ E T S+ +S S S S
Sbjct: 2569 PVQPEVALKRVPSPTPA------PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 232 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291
++ S SSS S + S+ S+ ++PS Q P+ + G R S S P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPRKP 2681
Query: 292 IHHIPSRRS------PAKTIAPQNAPRDESRGRS 319
I + RS + +PQ +PRD+ S
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 23/166 (13%)
Query: 104 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163
+P + + RS S S SS S S S S SS S SSSS SSS S SP + G Q
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ- 2657
Query: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
P+ SP K P + P + ID S + S SP
Sbjct: 2658 -------ALPKPASPKK----PPPGERRSRSPRKPIDSLRDSRSLS-----------YSP 2695
Query: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269
PSP +P Q SS S+ +PS SP
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
Score = 48.5 bits (114), Expect = 3e-05
Identities = 132/660 (20%), Positives = 220/660 (33%), Gaps = 115/660 (17%)
Query: 296 PSRRSPAKTIAPQNAPRDESR--------GRSSFYPDGGDQETAKTGKFLKRFTDEESRV 347
P +R PA T Q A +E + G S Y DG + + + K+ E +
Sbjct: 112 PGQR-PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 348 FLLDRGNTRD-----KEASKEKGSEKGRAEGEW-------EDQEALDYFSDKESGKQKFN 395
+ L R ++ K+ K+K ++GR + + + S+ ES K+K
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Query: 396 DSEGDDTEETEDYRQFR--------------KSVLADQGKSFATASHRNTEEEGLKYKSK 441
+++D ++ R +S AD S T+ R+ + +
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290
Query: 442 VSLKGNRESDGFREEKNYKLKETGYV-VERPSTTKDKHKEEDKNSERITVKKETQSPEQV 500
++ + + G R E + E G +RPS+ + T K+ SP +
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE-------------TATKQPSSPYED 337
Query: 501 KSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN 560
K + K+ P + E+S+ E P ++A L P+ + N
Sbjct: 338 KDKDKKEKSATRPS-----PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 561 RP--ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 618
P AS T+DR S K E KLPQ+S S S + H
Sbjct: 393 PPSEASPTRDR--------SPPKSPE--------KLPQSSSSESSPPSPQPTKVSRHASS 436
Query: 619 QYFK-------------SAAMTLNERFTSYQKATEEHST-------RQKSPEIHRR--ID 656
S++ T R K + HS R +SP +R
Sbjct: 437 SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSR 496
Query: 657 ISPSTLRKHTRLAGEE-----------RVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 705
T R H+R + R + + + + + RR + RS
Sbjct: 497 SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 706 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS-SR 764
RG S ++ R + +TP +S + R + +R S S +P+ SR
Sbjct: 557 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR 616
Query: 765 EEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNT 824
+++ + S R R RGR R+R G + S T
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR---TPARRGRSRSRT 673
Query: 825 TFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSS 884
++ + P +S+ R +RGR + RGR SGSS
Sbjct: 674 PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-VRRGRSHSRTPQRRGR-----SGSS 727
Score = 48.1 bits (113), Expect = 4e-05
Identities = 63/238 (26%), Positives = 89/238 (37%), Gaps = 46/238 (19%)
Query: 134 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 193
RSS S SSSS SSS S S S GS ++ + Q E LK P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA----- 2585
Query: 194 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
P E++ E P P+P SSS S
Sbjct: 2586 -PKEAVREGR----------------------PPEPTPAKRKRRSSSSSSS--------- 2613
Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313
++ S S S S S S S + SS S S +SP P ++ K +P+ P
Sbjct: 2614 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 314 ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE-ASKEKGSEKGR 370
E R RS P ++ + + L E R + + RD++ +S E+GS +G+
Sbjct: 2672 ERRSRSPRKP----IDSLRDSRSLSYSPVERRRP--SPQPSPRDQQSSSSERGSRRGQ 2723
Score = 47.0 bits (110), Expect = 8e-05
Identities = 88/385 (22%), Positives = 135/385 (35%), Gaps = 51/385 (13%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
S S RS+S S S++++R+ R+ RSRS + S+ R+ R R+
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQ-----RSRSGSSPEVDSKSRLSPR------RSRS 1598
Query: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR---SPKRRSVSS 122
G + R Q G + +PR RSR S K R S
Sbjct: 1599 GSSPEVKDKPRAAPRAQSGSDSSPEP---------KAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 123 QRSRS---------RSRRSYRSSRSPRSSSSRSSSPYSK-----SPVSKRRGSQEKQTKK 168
+ S S +SR + R SRS ++S +P + SP R+ ++++
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
A P+ S + + P + +S + SA+S P RSP S
Sbjct: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS----PRTKTTSRRGRSP-S 1764
Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
P P S+S S + + + S Q S RS G S Y
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY--HS 1822
Query: 289 NSPIHHIPSRRSPAKTIAPQNAP---RDESRGRSSFYPDGGDQETAKTGKFLKRFTDEES 345
SP SR S + P R SR R+S P + A + S
Sbjct: 1823 RSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR----SRS 1878
Query: 346 RVFLLDRGNTRDKEASKEKGSEKGR 370
R L+ R +R + + + + R
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSR 1903
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/156 (32%), Positives = 62/156 (39%), Gaps = 22/156 (14%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY- 61
R +S S SS S S S SSS S S S S SS S S + S S S + + +
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
Query: 62 --------RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113
R +R R+P R Y PV RR S P +S
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSL-----------SYSPVERRRPSPQPSPRDQQSS 2713
Query: 114 SPKRRSVSSQR--SRSRSRRSYRSSRSPRSSSSRSS 147
S +R S QR SRS S + R + SPR RSS
Sbjct: 2714 SSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 42.7 bits (99), Expect = 0.002
Identities = 161/801 (20%), Positives = 259/801 (32%), Gaps = 152/801 (18%)
Query: 109 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEK 164
RS + SP+ R S+ +S+ S SP+ SRSSSP S+SP+ + RG
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 165 QTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD---IWPGLSAYDN 221
G E+S +S S P D + + + +A S + + P A +
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
Query: 222 SPRSPHSPSP----------------IATPPSQSSSCSDAPMLSTVHSAKNTPSQH---- 261
PR SP + TPP + S +P +SA T SQ
Sbjct: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239
Query: 262 --------------SHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
SH E S S + P+ + + S+ S P
Sbjct: 1240 EVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
Query: 308 ------------------QNAP-RDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 348
N+P R+ S G + + G T F ++ + F
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 349 L----------LDRGNTR-----DKEASKEKGSEKGRAEGEWEDQEALDYF---SDKESG 390
L + +TR E S + + G + + LD +E
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Query: 391 KQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHR-NTEEEGLKYKSKVSLKGNRE 449
+ D T R S + S + H + G+K + +G E
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
Query: 450 SDGFREEKNYKLKETGYVVER-PSTTKDKHK----EEDKNSERITVKKET-------QSP 497
D E K L +T R PS+ + +K + +++ +V ++T Q
Sbjct: 1480 CDSSPEPK--ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 498 EQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLD 557
S++L SP D+ S + +PLR + + S PEV K P
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS--PEVDSKSRLSPRR 1595
Query: 558 DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS---------ESFIQH 608
+ + KD+ A+ S LP+ S+S S E
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655
Query: 609 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS---------- 658
S H K + + + + E T + S+R SPE+ R+ +S
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR-SSPELTRKARLSRRSRSASSSP 1714
Query: 659 ---PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR---------------- 699
T +H R E + ++ R S+ R
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 700 ----RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKR---EQDHSRSS 752
R K R+ R D GS +S+ R+Q + + H R Q+ SR+S
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 753 S---SSASPSSPSSREEKESK 770
S S + P+SR+ S+
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSR 1855
Score = 41.6 bits (96), Expect = 0.003
Identities = 136/685 (19%), Positives = 234/685 (34%), Gaps = 87/685 (12%)
Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175
+R +VS +S+S+ S + P +SS +S + + + E +
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 176 ESPLKSK-----SQEEPKDT-------FEHDPSESIDEFNKSSA--TSGDIWP------G 215
PL ++ S E +D E DPS + E + S+ +S ++ P G
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAG 1395
Query: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 275
+S+ + S SP + TP + SS + +P + TPS+ S S R GSG
Sbjct: 1396 MSS-NQSISSPVLDAVPRTPSRERSSSASSPEMKD--GLPRTPSRRSRSGSSPGLRDGSG 1452
Query: 276 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGK 335
+ SR+S S +SP ++ PR SRGRS + +++ K
Sbjct: 1453 T----PSRHSLSGSSP--------------GMKDIPRTPSRGRS-------ECDSSPEPK 1487
Query: 336 FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFN 395
L + SR N + +E+ + + + + L S S ++
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 396 DSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFRE 455
E +E S + K+ R+ + SK L R G
Sbjct: 1548 KPSASPQERSES-----DSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602
Query: 456 EKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 515
E +K+ R + D E + R + + ++S K P
Sbjct: 1603 E----VKDKPRAAPRAQSGSDSSPEPKAPAPR-ALPRRSRSGSSSKGRG---------PS 1648
Query: 516 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 575
+ + E S + + S P+ K + P + P K RL +
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
Query: 576 VHSVKKEQEFRSIFDHIKLPQAS------KSTSESFIQHIVSLVHHVKEQYFKSAAMTLN 629
S E R+ H + P S KS S + S + +S +
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
Query: 630 --ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR 687
+R S + + +TR++ R S ST R+ R RV + R
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRD-----RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823
Query: 688 CDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQD 747
+ + R + RG S+ S + +P +K +S + H+R +
Sbjct: 1824 SPARQ-----ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
Query: 748 HSR--SSSSSASPSSPSSREEKESK 770
+ S S S +SP SR S+
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSR 1903
Score = 39.3 bits (90), Expect = 0.017
Identities = 52/263 (19%), Positives = 89/263 (33%), Gaps = 21/263 (7%)
Query: 85 GGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSS 144
GG+ G RP H + + R +S S R +R + +
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP 165
Query: 145 RSSSPY--------SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPS 196
PY S+SP K++ +K+ KK G E S + + ++ K S
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQK---KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 197 ESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS--PSPIATPPSQSSSCSDAPMLSTVHSA 254
ES ++S + D + S P+P + +S+S A T S
Sbjct: 223 ESKKRKHRSPTPKSK----RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 255 KNTPSQHSHSIQ---HSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311
+ + +H+ SP SG G G + +S + S + K +
Sbjct: 279 SRSAAAKTHTTALAGRSPS-PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 312 RDESRGRSSFYPDGGDQETAKTG 334
+D+ + S E + TG
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTG 360
Score = 35.0 bits (79), Expect = 0.32
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 15/116 (12%)
Query: 706 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSS----------- 754
K R +GSR S + + +TP + +S + ++ R SRS+SS
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 755 ---SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGR 807
S S SSP E+ S + R + G + +PRG R R R R
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG-LQRSRSRSR 1778
Score = 34.7 bits (78), Expect = 0.42
Identities = 46/221 (20%), Positives = 85/221 (38%), Gaps = 22/221 (9%)
Query: 622 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 681
+S + T R S + +R +SP + RR S R R +G R + ++
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSP-VRRR-----SRSRSPARRSGRSRS-RTPARR 655
Query: 682 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 741
G + R + R R + ++ G S+ + R + +TP+ + + S
Sbjct: 656 GRSRSRTPARRGRS----RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRS----RSRSL 707
Query: 742 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE----YSGFAGVSRPRG 797
+R + HSR+ S S R+ K +R + EMK+ +S PR
Sbjct: 708 VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS 767
Query: 798 TFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPE 838
+ + R R +G++ P + T +R + P+
Sbjct: 768 ---KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPK 805
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 96.3 bits (238), Expect = 1e-19
Identities = 98/347 (28%), Positives = 136/347 (39%), Gaps = 64/347 (18%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G S+ R S RS+S S + R SRS S K RSRSR+ ++R R R S + RD
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA-RDRSRSRSPYKARDRSRSRSPNKARDC 437
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR--RGRSRSRSPKRRS 119
+R PY R R R + R SRSP R RSRSRSP +
Sbjct: 438 SRSRS---PYKARDRSRSRSPNKARDHSR-----------SRSPNKARDRSRSRSPSKER 483
Query: 120 VSSQRSRSRSRRSYRSSRSP---------RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
SQ R +R SRSP RSSS S+SP +R+ Q + K
Sbjct: 484 DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543
Query: 171 GEPQEESP--------LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222
Q SP +S S+E + + E ++SS+ D +
Sbjct: 544 DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSR 595
Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282
RSP+ S + P + S + +HS +P + G+ S SS
Sbjct: 596 SRSPNKQSGYSRPRASS-------------------KEKAHSRSRTPSKEGNHSQSRTSS 636
Query: 283 RYSPSQNSPIHHIPS-RRSPAKT--IAPQNAPRDESRGRSSFYPDGG 326
+ S S + P +RSP +T ++ P S S +P GG
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
Score = 77.0 bits (188), Expect = 7e-14
Identities = 120/470 (25%), Positives = 179/470 (38%), Gaps = 109/470 (23%)
Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRR 69
SSR KS +Q+S+RSR +SHS+ R RSRS + R+ SR R +S
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQS-RSPRRSRSGSQKRTHSRVRSHS--------------- 306
Query: 70 PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHS--------------------------- 102
W R HS
Sbjct: 307 ---------------------------WKRNHSRARSRTRKGILSQMGRHSQSRSHSKGK 339
Query: 103 -----RSPRRGRSR--SRSP-KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
R+PRRGRS SR+P K RS S RS S+ R +R S SPR S RS S SP
Sbjct: 340 SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK-ERDHRGSSSPRKESGRSQ---SGSP 395
Query: 155 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE-HDPSESIDEFNKSSATSGDIW 213
+R S+ + KA + SP K++ + + + D S S + K+ S
Sbjct: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPY-KARDRSRSRS 454
Query: 214 PGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQ---HSHSIQHSPE 270
P + + RSP+ ++ S S +P HS +PS+ H S S E
Sbjct: 455 PNKARDHSRSRSPNK--------ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 271 RSGSGSVGNGSSRYSPSQNSPIHHIPSR--RSPAK--TIAPQNAPRDESRGRSSFYPDGG 326
R S + R SP R RSP K + +P +E R S P
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP-SK 565
Query: 327 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSD 386
+++ + K +SR +R ++R + +K+ G + RA + E +
Sbjct: 566 ERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSK-EKAHSRSRTPS 624
Query: 387 KES--GKQKFNDSEGDDTEET----EDYRQ--FRKSVLADQGKSFATASH 428
KE + + + E D ++ T D+++ R S L+ T+SH
Sbjct: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674
Score = 74.7 bits (182), Expect = 4e-13
Identities = 170/773 (21%), Positives = 268/773 (34%), Gaps = 139/773 (17%)
Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSR--SRSRTYSRSRSRDRMYSRDYRRDYRNNRGM 67
+SR+ S SSS+S ++S S K+ S+R SRSR S++R+ R+ S D R +
Sbjct: 51 TSRNSVMSPSSSKS-TKSTSTKRAPSNRPSSRSRVRSKARTPSRV-STDTRTSKASKASD 108
Query: 68 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRS 127
R + RG H G P RR SRS +R SR+ +P R
Sbjct: 109 VRCHQRRGT------------HSRGRTP--GRRGSRSSKRSPSRASTPGR---------- 144
Query: 128 RSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEP 187
R+ + +SR +P S+ S+ + +T E + L KS P
Sbjct: 145 -----IRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP 199
Query: 188 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP-----PSQSSSC 242
+ SE + + + P DN SP S + + PS+ S
Sbjct: 200 GGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP--SPSSSRKVKSYGQMIIPSREKSY 257
Query: 243 SDAPMLSTVHS---AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 299
S M S V S A SHS SP RS SGS SR S + +H +R
Sbjct: 258 SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR-SHSWKRNHSRARS 316
Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 359
K I Q +SR S GK + +SR R + +
Sbjct: 317 RTRKGILSQMGRHSQSRSHSK-------------GK-----SQNQSRTPRRGRSHNWSRN 358
Query: 360 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 419
SKE+ R+ + D KESG+ + G ++ + R + D+
Sbjct: 359 PSKERSHSHSRSSSKERDHRGSSS-PRKESGRSQ----SGSPNKQRDHSRSRSPNKARDR 413
Query: 420 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHK 479
+S + R+ S N+ D R YK ++ S ++ +K
Sbjct: 414 SRSRSPYKARDRSR---------SRSPNKARDCSRSRSPYKARDR-------SRSRSPNK 457
Query: 480 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 539
D + R K +S + S++ +D P ++E+ R SP + +
Sbjct: 458 ARDHSRSRSPNKARDRSRSRSPSKE-RDHSQLGSP------SKERDHRRSRSPSKERQCR 510
Query: 540 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 599
+ + D R S +K+R + S KE++ S+
Sbjct: 511 QSRSSSKER---------DHRRSRSPSKERQRRQS--RSPNKERD------------RSQ 547
Query: 600 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 659
S S S +E+ + + ER + R S E RR S
Sbjct: 548 SRSPS------------EEREHRQSRSPSKER--------DRRRWRSPSKERERRQSRSS 587
Query: 660 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 719
S R H+R + Q G + R S + H R + S+ES
Sbjct: 588 SEERDHSRSRSPNK------QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDP 641
Query: 720 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKE 772
S+ D+K + R + S S S PS + + +S+ +
Sbjct: 642 SQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQAD 694
Score = 73.2 bits (178), Expect = 1e-12
Identities = 143/597 (23%), Positives = 232/597 (38%), Gaps = 66/597 (11%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
GR SRS S RS SR+ S+ R R+H + +SR R+ T + SR + Y R R
Sbjct: 125 GRRGSRS-SKRSPSRA--STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRP--RTS 179
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP-KRRSV 120
R +P + Y GG R V + S + ++ + P K +S
Sbjct: 180 NRERSDSQPRNL--SKKSYRPPGGSGIGRSSELAV-----TPSTAKCQTPTGIPSKEKSD 232
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS--QEKQTKKAEGEPQEESP 178
+ S SR +SY P S YS + +S R S Q + + Q SP
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKS-----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSP 287
Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRS-PHSPSPIATPPS 237
+S+S + K T S S N S A S LS +S HS
Sbjct: 288 RRSRSGSQ-KRTHSRVRSHSWKR-NHSRARSRTRKGILSQMGRHSQSRSHS-------KG 338
Query: 238 QSSSCSDAPMLSTVHSAKNTPSQ---HSHSIQHSPERS--GSGSVGNGSSR-YSPSQNSP 291
+S + S P H+ PS+ HSHS S ER GS S S R S S N
Sbjct: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
Query: 292 IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD 351
H S RSP N RD SR RS + D+ +++ + + S D
Sbjct: 399 RDHSRS-RSP-------NKARDRSRSRSPY--KARDRSRSRSPNKARDCSRSRSPYKARD 448
Query: 352 RGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQF 411
R +R +++ + +A D + K++ + G ++E D+R+
Sbjct: 449 RSRSRSPNKARDHSRSR-------SPNKARDRSRSRSPSKERDHSQLGSPSKE-RDHRRS 500
Query: 412 RKSVLADQGKSFATAS----HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYV 467
R Q + ++S HR + + + + S N+E D R + +E +
Sbjct: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD--RSQSRSPSEEREHR 558
Query: 468 VER-PSTTKDKH--KEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLD---A 521
R PS +D+ + K ER + ++ + +S YS P + + +
Sbjct: 559 QSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS 618
Query: 522 REKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHS 578
R ++ +E + + + + +S + + +P R +SL+++R + T HS
Sbjct: 619 RSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
Score = 56.2 bits (134), Expect = 1e-07
Identities = 148/715 (20%), Positives = 258/715 (36%), Gaps = 84/715 (11%)
Query: 141 SSSSRSSSP-YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESI 199
SS RSS P S +P + + + + + +P +S +P + S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 200 DEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259
+ KS++T A N P S A PS+ S+ + S +
Sbjct: 62 SKSTKSTSTK-------RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114
Query: 260 QHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319
+ +HS +P R GS S SR S H +R A + + + SRG+S
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG--ARPGMASRVRTPTSQQKGSRGKS 172
Query: 320 SFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQE 379
P ++E + + R ++S G R E + + K + +E
Sbjct: 173 YGRPRTSNRERSDSQP---RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKE 229
Query: 380 ALDYFSDKESGKQKF--------NDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNT 431
D S S K K + TE + + + ++ + +S + +
Sbjct: 230 KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR 289
Query: 432 EEEGLKYK--SKV---SLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSE 486
G + + S+V S K N R K L + G + S +K K + + +
Sbjct: 290 SRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI-LSQMGRHSQSRSHSKGKSQNQSRTPR 348
Query: 487 RITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE 546
R +++P + +S +S K D R S+ R+ES S + + +
Sbjct: 349 RGRSHNWSRNPSKERSHS------HSRSSSKERDHRGSSSPRKESGR--SQSGSPNKQRD 400
Query: 547 VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFI 606
+P D +R S K R + + S K ++ K S+S S +
Sbjct: 401 HSRSRSPNKARDRSRSRSPYKARDRSRS--RSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
Query: 607 QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHT 666
+ + R S KA + +R S E SPS R H
Sbjct: 459 RD--------------------HSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
Query: 667 RLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEK 725
R + ++ ++ R S + H RR + SKER + S R Q +
Sbjct: 499 RSRSPSK------ERQCRQSRSSSKERDH---RRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 726 TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 785
+P + +E++ + SK E+D R S S RE ++S+ EE + H +
Sbjct: 550 SPSEEREHRQSRSPSK---ERDRRRWRSPS------KERERRQSRSSSEE--RDHSRSRS 598
Query: 786 YSGFAGVSRPRGTFFRIRGRGRAR-----GVFAGTNTGPNNSNTTFQKRPKEEEW 835
+ +G SRPR + + + R+R G + + T S+ + P+ +W
Sbjct: 599 PNKQSGYSRPRAS-SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDW 652
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 93.6 bits (231), Expect = 8e-19
Identities = 100/288 (34%), Positives = 133/288 (46%), Gaps = 32/288 (11%)
Query: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD-- 60
S+S+S S SRS SRS+S SRSRS+S SR K+ SRS S+ SRSRS SR +D
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 61 ---YRNNRGMRRPYG-------------YRGRGRGYYQGGGGRYHRG-GYRPVWNRRHSR 103
+NN + +P R + R + G RG + SR
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 104 SPRRGRSRSRSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
S +G SRSRS R +S ++ R RSR RS RS S RS SK + GS
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR--DSKAGSS 391
Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESID-EFNKSSATSGDIWPGLS-AYD 220
+K+ K+ Q SP +S S+E EH SES E S +G S +
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKER-----EHAKSESSQREGRGESENAGTNQETRSRSRS 446
Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268
NS P+ PS + S+S+S + + S SA +PS+ S S HS
Sbjct: 447 NSKSKPNLPSE-SRSRSKSASKTRSRSKSRSRSASRSPSR-SRSRSHS 492
Score = 67.8 bits (164), Expect = 4e-11
Identities = 76/286 (26%), Positives = 110/286 (38%), Gaps = 23/286 (8%)
Query: 101 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160
+ R R + S +RRS S RS SRSR R SR RS S S S +SKS R G
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225
Query: 161 SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD 220
S+ + K+ Q S K + P S S KS + S D A +
Sbjct: 226 SRSR--SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA---GKSRSKSKD-----QAEE 275
Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLS---TVHSAKNTPSQHSHSIQHSPERSGSGSV 277
+ + P + PS+ S S + S V K S + S +S S S
Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 278 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 337
G SR S++ +R K ++ R SR +S G + +K G
Sbjct: 336 SKGGSR---SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Query: 338 KRFTDEESRVFLLDRGNTRDKEASKEK---GSEKGRAEGEWEDQEA 380
K+ ++ R + + + SKE+ SE + EG E + A
Sbjct: 393 KKKKEDTDR----SQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Score = 67.4 bits (163), Expect = 6e-11
Identities = 74/224 (33%), Positives = 97/224 (43%), Gaps = 49/224 (21%)
Query: 1 MGRSNSRS---HSSRSKSRSQSSSR----------SRSRSHSRKKRYS-SRSRSRTYSRS 46
+G+ SRS H S+SKSRS+S R SR RS + R S SRSRS+ SRS
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 47 RSRDRMYSRDYR------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR 100
RSR R S+D R R+ +R R R R RG + + + +R
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 101 HSRSPRRGRSRSRSPKRRSVSSQR----------------SRSRSRRSYRSSRSPRSSSS 144
SRSP R S+ R +S SSQR SRSRS S P S S
Sbjct: 403 QSRSPSRSVSKERE-HAKSESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRS 460
Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188
RS S SK R + +++ A SP +S+S+ +
Sbjct: 461 RSKS------ASKTRSRSKSRSRSA-----SRSPSRSRSRSHSR 493
Score = 48.5 bits (114), Expect = 3e-05
Identities = 65/324 (20%), Positives = 113/324 (34%), Gaps = 46/324 (14%)
Query: 629 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 688
+ R SY ++ +R +S + S S+ H++ R K + +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 689 DSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEK-------------TPKDYKEYK 734
S + KE+S+ R S G SR S + +EK +P +K
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 735 SYKDDSKHKREQDHSRSS-------------SSSASPSSPSSREEKESKKEREEEFKTHH 781
+ S+ +R ++ R S S S S S SR S+ + +++ K
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358
Query: 782 EMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTP 841
+E S SR R R R RG R AG++ K+ K+E+ D +
Sbjct: 359 RSREES--RSRSRSRSKSERSRKRGSKRDSKAGSS-----------KKKKKEDTDRSQSR 405
Query: 842 KSKKYFLHDDRDDGVDYWAKRGRGR----GTFQ--RGRGRFNFKKSGSSPKWTHDKYQGD 895
+ + + + GRG GT Q R R R N K + P + + +
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465
Query: 896 GIVEDEEETMENNEEKKDRRKEEK 919
++ + + R +
Sbjct: 466 SKTRSRSKSRSRSASRSPSRSRSR 489
Score = 47.0 bits (110), Expect = 8e-05
Identities = 43/171 (25%), Positives = 69/171 (40%), Gaps = 25/171 (14%)
Query: 622 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 681
KS + + ++ Q + +SP H+ + +R +ER +EE +
Sbjct: 264 KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS--------KSKSRSRSQERRVEEEKRG 315
Query: 682 GDKKLRCDSADLRHDIDRRR---------KERSKERGDSKG---SRESSGSRKQEKTPKD 729
+ R LR R R + RSK + KG SRE S SR + ++ +
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
Query: 730 YKEYKSYKDD-----SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREE 775
+ K D SK K+++D RS S S S S RE +S+ + E
Sbjct: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQRE 426
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/231 (22%), Positives = 86/231 (37%), Gaps = 33/231 (14%)
Query: 678 ENQKGDKKLRCDSADLRHDIDRRRKERSKER----GDSKGSRESSGSRKQEKTPKDYKEY 733
E++ G ++ R S H R R S++ G SK S S SR + + K
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 734 KSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK-------------TH 780
+ S+ K+E+ S S S S S + + +SK + EE+ + +
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 781 HEMKEYSGFAGVSR-----PRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEW 835
H+ K S R RG+ RGR + + + + + + + R + +
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSV--SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 836 DPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPK 886
D K +K + R R R + R RG K+GSS K
Sbjct: 352 DKR---KGRKRSREESRS------RSRSRSKSERSRKRGSKRDSKAGSSKK 393
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 8/55 (14%)
Query: 3 RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYS 54
RSNS+S S S+SRS+S+S++RSRS SR SRS SR+ SRSRSR S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSR-----SRSASRSPSRSRSRSHSRS 494
Score = 43.5 bits (101), Expect = 0.001
Identities = 75/361 (20%), Positives = 136/361 (37%), Gaps = 51/361 (14%)
Query: 431 TEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKD--------KHKEED 482
TE G K + G+R + +++ + R S ++ K +
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 483 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 542
++ R K ++S + +S+K K SP ++EKS R S + + + D
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSR---SP-------SKEKSRSRSHSAGKSRSKSKDQ 272
Query: 543 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 602
+++ D+ +P S + R + + S +E+ + K S+ S
Sbjct: 273 AEEKIQNN------DNVGKPKSRSPSRHKSKSKSRSRSQERRV----EEEKRGSVSRGRS 322
Query: 603 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 662
+ SL K + + R S K+ ++ R++S E R S S
Sbjct: 323 QE-----KSLRQSRSRSRSKGGSRS---RSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 663 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS-----KGSRES 717
+ +R G +R K + K KK D + R KER + +S +G E+
Sbjct: 375 ER-SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESEN 433
Query: 718 SGSRKQEKT---------PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 768
+G+ ++ ++ P E +S + R + SRS S+S SPS SR
Sbjct: 434 AGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Query: 769 S 769
S
Sbjct: 494 S 494
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
S S S S++P S AK S S++ S +RSG
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 57.0 bits (136), Expect = 8e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 399 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 458
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
Query: 459 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 514
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 515 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 574
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
Query: 575 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 634
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
Query: 635 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 681
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 682 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 741
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
Query: 742 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
KRE + + S S S S ++SKK ++ K H
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 221 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
Query: 280 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 312
++ +P QN P +RSP Q P+
Sbjct: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
Query: 313 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 367
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
Query: 368 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 419
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
Query: 420 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 475
K T + +E + Y +K D R+ K+ S T
Sbjct: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
Query: 476 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 532
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
Query: 533 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 588
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 589 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 644
+ H + + +S S S S S + T++ S + S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
Query: 645 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 702
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
Query: 703 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 761
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 762 SSREEKESKKEREEEFKTHHEMKE 785
+E+E KKER + K+
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKD 681
Score = 47.8 bits (112), Expect = 5e-05
Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G + SH + +++ Q + RSRS + ++ + R R + + + + +D++
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
+++R R+ R + R G V RH +S ++ K+ S
Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
SS RS S S S + ++ + SRS S KS S ++ S++ ++K
Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801
Score = 47.4 bits (111), Expect = 6e-05
Identities = 105/507 (20%), Positives = 178/507 (35%), Gaps = 67/507 (13%)
Query: 432 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 488
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 489 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 544
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 545 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 603
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 604 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK------- 461
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
+ L+ E + + +KK + + + KE+ K+ GS S S
Sbjct: 462 ---EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
+T S S + SR+SS S+SP + +K + R K
Sbjct: 519 SSNSRTSSTSSTVSS----SSYSSSSGSSRTSSRSSSP-----KRKKRHSRSRSPTIKAR 569
Query: 781 HEM-KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY 839
+ YS + R R++ R R R SN +R + P
Sbjct: 570 RSRSRSYSRRIKIESNRA---RVKIRDRRR------------SNRNSIERERRRNRSPSR 614
Query: 840 TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVE 899
+ + D R + R R + QRG N K K K + ++
Sbjct: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
Query: 900 ------DEEETMENNEEKKDRRKEEKE 920
D+E E ++ K+ +++EEK+
Sbjct: 675 KDRKKKDKEREREQDKRKEKQKREEKD 701
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R +
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
N ++ +G Q R + R +R + R K
Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
SSQ R + +R + S S S + SK+ + S++ + G E
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
SP SK ++ K +H S S+++ +S
Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 165 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 222 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 270
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 271 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 326
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 327 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 384
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 385 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 441
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 442 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 496
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 40.0 bits (92), Expect = 0.010
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
E ++EF S + A + R+P+ + + P +
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 367
+ SR RS + +R E +R R RD+ S E
Sbjct: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 368 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 427
+ R N S + + + R++ A + +S
Sbjct: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
Query: 428 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 487
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
Query: 488 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 546
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
Query: 547 VK 548
K
Sbjct: 741 KK 742
Score = 39.7 bits (91), Expect = 0.013
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
+ + ML T T + + + +
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 348
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 349 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 403
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 404 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 463
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
Query: 464 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 513
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
Query: 514 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 573
N ++ E+ R SP R + R S ++DR
Sbjct: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
Query: 574 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 633
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 634 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 693
++ ++ +QK E + L++ ER F K +R
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
Query: 694 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 753
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
Query: 754 SSASPSSPSSREEKESKKER 773
S +SR+ K + R
Sbjct: 786 KSQRSGKKASRKHKSKSRSR 805
Score = 34.3 bits (77), Expect = 0.55
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
GRS+S S S + +++ SRSRS + +R ++ + S+SRSR
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
+S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+
Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
S S S S++P S AK S S++ S +RSG
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 57.0 bits (136), Expect = 8e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 399 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 458
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
Query: 459 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 514
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 515 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 574
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
Query: 575 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 634
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
Query: 635 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 681
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 682 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 741
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
Query: 742 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
KRE + + S S S S ++SKK ++ K H
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 221 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
Query: 280 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 312
++ +P QN P +RSP Q P+
Sbjct: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
Query: 313 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 367
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
Query: 368 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 419
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
Query: 420 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 475
K T + +E + Y +K D R+ K+ S T
Sbjct: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
Query: 476 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 532
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
Query: 533 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 588
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 589 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 644
+ H + + +S S S S S + T++ S + S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
Query: 645 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 702
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
Query: 703 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 761
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 762 SSREEKESKKEREEEFKTHHEMKE 785
+E+E KKER + K+
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKD 681
Score = 47.8 bits (112), Expect = 5e-05
Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G + SH + +++ Q + RSRS + ++ + R R + + + + +D++
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
+++R R+ R + R G V RH +S ++ K+ S
Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
SS RS S S S + ++ + SRS S KS S ++ S++ ++K
Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801
Score = 47.4 bits (111), Expect = 6e-05
Identities = 105/507 (20%), Positives = 178/507 (35%), Gaps = 67/507 (13%)
Query: 432 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 488
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 489 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 544
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 545 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 603
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 604 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK------- 461
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
+ L+ E + + +KK + + + KE+ K+ GS S S
Sbjct: 462 ---EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
+T S S + SR+SS S+SP + +K + R K
Sbjct: 519 SSNSRTSSTSSTVSS----SSYSSSSGSSRTSSRSSSP-----KRKKRHSRSRSPTIKAR 569
Query: 781 HEM-KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY 839
+ YS + R R++ R R R SN +R + P
Sbjct: 570 RSRSRSYSRRIKIESNRA---RVKIRDRRR------------SNRNSIERERRRNRSPSR 614
Query: 840 TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVE 899
+ + D R + R R + QRG N K K K + ++
Sbjct: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
Query: 900 ------DEEETMENNEEKKDRRKEEKE 920
D+E E ++ K+ +++EEK+
Sbjct: 675 KDRKKKDKEREREQDKRKEKQKREEKD 701
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R +
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
N ++ +G Q R + R +R + R K
Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
SSQ R + +R + S S S + SK+ + S++ + G E
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
SP SK ++ K +H S S+++ +S
Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 165 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 222 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 270
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 271 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 326
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 327 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 384
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 385 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 441
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 442 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 496
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 40.0 bits (92), Expect = 0.010
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
E ++EF S + A + R+P+ + + P +
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 367
+ SR RS + +R E +R R RD+ S E
Sbjct: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 368 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 427
+ R N S + + + R++ A + +S
Sbjct: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
Query: 428 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 487
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
Query: 488 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 546
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
Query: 547 VK 548
K
Sbjct: 741 KK 742
Score = 39.7 bits (91), Expect = 0.013
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
+ + ML T T + + + +
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 348
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 349 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 403
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 404 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 463
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
Query: 464 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 513
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
Query: 514 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 573
N ++ E+ R SP R + R S ++DR
Sbjct: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
Query: 574 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 633
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 634 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 693
++ ++ +QK E + L++ ER F K +R
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
Query: 694 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 753
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
Query: 754 SSASPSSPSSREEKESKKER 773
S +SR+ K + R
Sbjct: 786 KSQRSGKKASRKHKSKSRSR 805
Score = 34.3 bits (77), Expect = 0.55
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
GRS+S S S + +++ SRSRS + +R ++ + S+SRSR
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
+S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+
Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 88.6 bits (218), Expect = 2e-17
Identities = 85/224 (37%), Positives = 105/224 (46%), Gaps = 37/224 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----YSS----RSRSRTYSRSRSRDRMYS 54
R +S S SS S SR+ SSSRS SRS SR +R Y S RSRSR++SRSRSR R YS
Sbjct: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
Query: 55 RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 92
R R R++ G R YG R R R G RY RGG
Sbjct: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492
Query: 93 -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 150
R W+ SRS RSRS SP S S RSRSRSR S R +R ++SP
Sbjct: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 151 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
+ K + K+T A+ + + LK + Q+ F+ D
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
Score = 42.4 bits (98), Expect = 0.002
Identities = 91/431 (21%), Positives = 156/431 (36%), Gaps = 80/431 (18%)
Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 163
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
Query: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
+++ P E K TF S DE ++A + + +P
Sbjct: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
Query: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG--- 280
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
Query: 281 -------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESRGRS 319
S RYS S++ H RSPA+ PR SR RS
Sbjct: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSRSRS 473
Query: 320 SFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEGEWE 376
GD+ + G+ L+ + SR R + + S + R+
Sbjct: 474 ----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
Query: 377 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL 436
Q + ++ + + + G+ ++TE GK A + T +E L
Sbjct: 529 SQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQEKL 578
Query: 437 KYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 496
K + + +L NR+ F+ +K + + +H+ +++ E + ++ +
Sbjct: 579 KLRMQKAL--NRQ---FKADKK---------AAQEKMIQQEHERQEREDELRAMARKIRM 624
Query: 497 PEQVKSEKLKD 507
E+ + EK ++
Sbjct: 625 KERERREKERE 635
Score = 41.2 bits (95), Expect = 0.004
Identities = 81/310 (26%), Positives = 121/310 (39%), Gaps = 42/310 (13%)
Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
R+ S +RRS SS S S SR S SSRS SSRSSS S+R G + + A
Sbjct: 369 RNASARRRSSSSSSSSSASRTS--SSRS----SSRSSSR------SRRGGGYYRSGRHAR 416
Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
+ S +S+S+ + ++ SG Y SP
Sbjct: 417 SRSRSWSRSRSRSRRYSRSR------------SRGRRHSGGGSRDGHRYSRSPARRGGYG 464
Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
P S+S S D ++ S+ S SP RS S + S SPSQ+
Sbjct: 465 PRRRSRSRSHS-GDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSP-SPSQS- 521
Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ----ETA---KTGKFLKRFTDE 343
RS +++ +P +P E R + P G++ E A +TG + T +
Sbjct: 522 ------RSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQ 575
Query: 344 ESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 403
E + + R +A K+ EK + E E QE D + K + + E + E
Sbjct: 576 EKLKLRMQKALNRQFKADKKAAQEK-MIQQEHERQEREDELR-AMARKIRMKERERREKE 633
Query: 404 ETEDYRQFRK 413
E RQ+ +
Sbjct: 634 REEWERQYSR 643
Score = 39.7 bits (91), Expect = 0.013
Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 35/182 (19%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS---RKKRYSSRSRSRTYSRSRSRDRM-------- 52
S+SRS SS S S S+S S +RSRSHS + R SRSRS++ S S +R+++
Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 53 ----------------------YSRDYRRDYRNNRGMRRPY--GYRGRGRGYYQGGGGRY 88
+ + R + + R + + Q R
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
Query: 89 HRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148
R R+ R R + R R S Q R S S S R S SRS S
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Query: 149 PY 150
P+
Sbjct: 670 PH 671
Score = 39.3 bits (90), Expect = 0.017
Identities = 87/404 (21%), Positives = 138/404 (34%), Gaps = 48/404 (11%)
Query: 94 RPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS-SRSPRSSSSRSSSPYSK 152
+ +++ R SR RR R + + R +S R +Y RSP SSS S S S+
Sbjct: 259 KAMYSGRRSRRQRR-EFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRS-RSR 316
Query: 153 SPVSKRR----------GSQEKQTKKAEG---------------EPQEESPLKSKSQEEP 187
SP R GS E+ A +P +P ++ S
Sbjct: 317 SPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
Query: 188 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS-PIATPPSQSSSCSDAP 246
+ S S ++SS+ S Y S R S S + S+S S +
Sbjct: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 247 MLSTVHSAKNTPSQHSHSIQHSPERSG-------SGSVGNGSSRYSPSQNSPIHHIPSRR 299
HS S+ H SP R G S S + RY HH SR
Sbjct: 437 SRGRRHSGGG--SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRS 494
Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRG-----N 354
+ +++P R S RS + Q +++ + + +R L
Sbjct: 495 RSSWSLSPS---RSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVG 551
Query: 355 TRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE--ETEDYRQFR 412
+ K+ G E G A+ + QE L K +Q D + + + E RQ R
Sbjct: 552 EKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQER 611
Query: 413 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREE 456
+ L + E+E +++ + S + S + E
Sbjct: 612 EDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSRE 655
Score = 33.5 bits (75), Expect = 0.93
Identities = 21/89 (23%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Query: 664 KHTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSR 721
K + A +E++ ++E+++ +++ LR + +R +R R+E+ +E + + SR+S
Sbjct: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQS---- 645
Query: 722 KQEKTPKDYKEYKSYKDDSKHKREQDHSR 750
+ +P+ +EY S + S+ + H R
Sbjct: 646 -RSPSPRYSREYSSSRRRSRSRSRSPHYR 673
Score = 32.0 bits (71), Expect = 2.7
Identities = 18/53 (33%), Positives = 25/53 (47%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR 55
R+ +R + + R + R +SR+ R S SR YS SR R R SR
Sbjct: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 85.5 bits (210), Expect = 2e-16
Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G+SN R RS+S ++S SRS S+SHSR+KR S+ RSR+++RSRSR
Sbjct: 298 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 345
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
++ R + P+ R + R R +R HSR R+ K R
Sbjct: 346 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
R + R R R R + K + +E++ +K + +++ K
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 450
Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
K Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS
Sbjct: 451 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 506
Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282
S + + +PS S + I ER S S+ S+
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566
Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314
+ S S H+ S +K + ++APR E
Sbjct: 567 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 54.7 bits (130), Expect = 4e-07
Identities = 76/367 (20%), Positives = 135/367 (36%), Gaps = 42/367 (11%)
Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
G+ D + HS + I PP + + + + + S S +I+ PE S
Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 300
Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326
G SR S S++S H +RS +K + ++ +D R +S
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 327 DQETAKTG---------KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWED 377
+E K+ K + E+ RV DR R++E +EK E+G+ + ++
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 378 QEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLK 437
+E D+E K+K D E + +E E R K D+ K + +E+ K
Sbjct: 421 RE-----KDREKDKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 438 YK-----------SKVSLKGNRESDGFREEKNYKLKETGYVVER-----PSTTKDKHKEE 481
K S+ S +RE R + + T ++R PS K++
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 482 DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASD 541
+ ER + + + K + D L KN + ++ +E + D
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Query: 542 SHRPEVK 548
P +
Sbjct: 594 KDAPRTE 600
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%)
Query: 636 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 695
+ +++ HS R++S HR + S R+ R + K + +K R S
Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376
Query: 696 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 743
D R K + KER D + RE R++EK ++ K + D + +
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 744 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 802
RE++H + +E EK+ KE +E+ K + + SR + R
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 803 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 862
R R R+R ++ P S T +K + P ++KK + D + +R
Sbjct: 497 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 546
Query: 863 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 912
R R T R G+ +K+ +S K + D V E +++ EE K
Sbjct: 547 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 49.3 bits (116), Expect = 2e-05
Identities = 74/355 (20%), Positives = 125/355 (35%), Gaps = 42/355 (11%)
Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
KR S+E++ ++ +++ +K K + + KD + E E K +
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 210 GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269
D D + ++ + +
Sbjct: 415 KD-------RDKEREKDRE--------KDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 270 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 329
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 507
Query: 330 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 389
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 508 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 562
Query: 390 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 444
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 563 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 612
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)
Query: 521 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 580
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359
Query: 581 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 640
K +E R K T E + VKE+ + ER +K
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 412
Query: 641 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 700
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 470
Query: 701 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 760
RK+ K R R + SR+ + ++ + +S + + R SS S S
Sbjct: 471 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 524
Query: 761 PSSREEKESKKEREEEFKTHHEMKEYS 787
P SR +K+ K+E+E + + +E S
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERS 551
Score = 43.9 bits (102), Expect = 7e-04
Identities = 74/368 (20%), Positives = 141/368 (38%), Gaps = 50/368 (13%)
Query: 419 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPST 473
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 284 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 338
Query: 474 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL 533
+ + +++D+ + KK ++S E+ KS D K D REK +E+ +
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD------KRKDTREK--IKEKERV 390
Query: 534 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 593
+ K + R + + K + R + +D+ +K++E +H K
Sbjct: 391 KEKDREKEREREKEREK-------EKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 594 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 653
K + +++ K + ++E+ +K ++ T +S R
Sbjct: 444 DRDKEKEKEQD-----------KEKEREKDRSKEIDEK----RKKDKKSRTPPRSYNASR 488
Query: 654 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 713
R S S R+ R R + K R S R+ D++R E+ ++ +
Sbjct: 489 R-SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR-EKERDHISERR 546
Query: 714 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 773
RE S S ++ +D KE + +S +E++H++ P S S+E + R
Sbjct: 547 ERERSTSMRKSSNDRDGKE--KLEKNSTSLKEKEHNKE------PDSSVSKEVDDKDAPR 598
Query: 774 EEEFKTHH 781
EE K H
Sbjct: 599 TEENKIQH 606
Score = 37.4 bits (85), Expect = 0.065
Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%)
Query: 710 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 769
+S S E G R + T K S K S+ KR Q RS S + S S ++ + S
Sbjct: 296 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 351
Query: 770 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 829
K ++ K+ K S + + T +I+ + R + + R
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 395
Query: 830 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 889
KE E + E K K+ + DRD +R + R K+ +
Sbjct: 396 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 438
Query: 890 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
+++ D E E+E + E +KDR KE E
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Score = 35.4 bits (80), Expect = 0.25
Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%)
Query: 637 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 696
K EE R + + I P + + + R G R + K
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 323
Query: 697 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 755
RR++ +SK R S SR R++ K+P K +R + SRS S
Sbjct: 324 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 375
Query: 756 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 785
+ +EKE +K+RE+E + E ++
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREK 407
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 85.5 bits (210), Expect = 2e-16
Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G+SN R RS+S ++S SRS S+SHSR+KR S+ RSR+++RSRSR
Sbjct: 182 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 229
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
++ R + P+ R + R R +R HSR R+ K R
Sbjct: 230 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
R + R R R R + K + +E++ +K + +++ K
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 334
Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
K Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS
Sbjct: 335 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 390
Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282
S + + +PS S + I ER S S+ S+
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450
Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314
+ S S H+ S +K + ++APR E
Sbjct: 451 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 54.7 bits (130), Expect = 4e-07
Identities = 76/367 (20%), Positives = 135/367 (36%), Gaps = 42/367 (11%)
Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
G+ D + HS + I PP + + + + + S S +I+ PE S
Sbjct: 127 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 184
Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326
G SR S S++S H +RS +K + ++ +D R +S
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 327 DQETAKTG---------KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWED 377
+E K+ K + E+ RV DR R++E +EK E+G+ + ++
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 378 QEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLK 437
+E D+E K+K D E + +E E R K D+ K + +E+ K
Sbjct: 305 RE-----KDREKDKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 438 YK-----------SKVSLKGNRESDGFREEKNYKLKETGYVVER-----PSTTKDKHKEE 481
K S+ S +RE R + + T ++R PS K++
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 482 DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASD 541
+ ER + + + K + D L KN + ++ +E + D
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 542 SHRPEVK 548
P +
Sbjct: 478 KDAPRTE 484
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%)
Query: 636 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 695
+ +++ HS R++S HR + S R+ R + K + +K R S
Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260
Query: 696 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 743
D R K + KER D + RE R++EK ++ K + D + +
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 744 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 802
RE++H + +E EK+ KE +E+ K + + SR + R
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 803 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 862
R R R+R ++ P S T +K + P ++KK + D + +R
Sbjct: 381 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 430
Query: 863 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 912
R R T R G+ +K+ +S K + D V E +++ EE K
Sbjct: 431 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 49.3 bits (116), Expect = 2e-05
Identities = 74/355 (20%), Positives = 125/355 (35%), Gaps = 42/355 (11%)
Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
KR S+E++ ++ +++ +K K + + KD + E E K +
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 210 GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269
D D + ++ + +
Sbjct: 299 KD-------RDKEREKDRE--------KDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 270 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 329
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 391
Query: 330 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 389
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 392 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 446
Query: 390 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 444
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 447 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 496
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)
Query: 521 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 580
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243
Query: 581 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 640
K +E R K T E + VKE+ + ER +K
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 296
Query: 641 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 700
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 354
Query: 701 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 760
RK+ K R R + SR+ + ++ + +S + + R SS S S
Sbjct: 355 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 408
Query: 761 PSSREEKESKKEREEEFKTHHEMKEYS 787
P SR +K+ K+E+E + + +E S
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERS 435
Score = 43.9 bits (102), Expect = 7e-04
Identities = 74/368 (20%), Positives = 141/368 (38%), Gaps = 50/368 (13%)
Query: 419 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPST 473
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 168 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 222
Query: 474 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL 533
+ + +++D+ + KK ++S E+ KS D K D REK +E+ +
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD------KRKDTREK--IKEKERV 274
Query: 534 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 593
+ K + R + + K + R + +D+ +K++E +H K
Sbjct: 275 KEKDREKEREREKEREK-------EKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 594 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 653
K + +++ K + ++E+ +K ++ T +S R
Sbjct: 328 DRDKEKEKEQD-----------KEKEREKDRSKEIDEK----RKKDKKSRTPPRSYNASR 372
Query: 654 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 713
R S S R+ R R + K R S R+ D++R E+ ++ +
Sbjct: 373 R-SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR-EKERDHISERR 430
Query: 714 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 773
RE S S ++ +D KE + +S +E++H++ P S S+E + R
Sbjct: 431 ERERSTSMRKSSNDRDGKE--KLEKNSTSLKEKEHNKE------PDSSVSKEVDDKDAPR 482
Query: 774 EEEFKTHH 781
EE K H
Sbjct: 483 TEENKIQH 490
Score = 37.4 bits (85), Expect = 0.065
Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%)
Query: 710 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 769
+S S E G R + T K S K S+ KR Q RS S + S S ++ + S
Sbjct: 180 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 235
Query: 770 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 829
K ++ K+ K S + + T +I+ + R + + R
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 279
Query: 830 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 889
KE E + E K K+ + DRD +R + R K+ +
Sbjct: 280 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 322
Query: 890 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
+++ D E E+E + E +KDR KE E
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Score = 35.4 bits (80), Expect = 0.25
Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%)
Query: 637 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 696
K EE R + + I P + + + R G R + K
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 207
Query: 697 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 755
RR++ +SK R S SR R++ K+P K +R + SRS S
Sbjct: 208 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 259
Query: 756 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 785
+ +EKE +K+RE+E + E ++
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREK 291
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 84.0 bits (206), Expect = 6e-16
Identities = 167/741 (22%), Positives = 274/741 (36%), Gaps = 94/741 (12%)
Query: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPR-SSSSRSSSP----YSKS 153
R SRSPRR +SRS SP+RRS +R R RS SRSPR + SRS SP K+
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-----SRSPRHRTKSRSPSPAPEKKEKT 220
Query: 154 P------VSKRRGSQEKQTKKAE----------GEPQEESPLKSKSQEEPKDTFEHDPSE 197
P V + S ++ T ++ EP+E SP K+ +E+ K E
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK--------E 272
Query: 198 SIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT 257
++S + S S PR H + P + S P +
Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
Query: 258 PSQHSHSIQHSP----ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS--PAKT--IAPQN 309
P H SP RS + G+ SS S SP P R S P KT ++P
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
Query: 310 APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKG 369
+P R R S P +T + + +SRV + G T K +K KG+EK
Sbjct: 393 SP-PRRRHRPS-PPATPPPKTRHSPTPQQSNRTRKSRV-SVSPGRTSGK-VTKHKGTEKR 448
Query: 370 RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFAT---- 425
+ ++ +E K + D ++ YR+ + +D G S ++
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKM--AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506
Query: 426 --ASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEE-- 481
SH E G + + S R + ++ + G PS + +
Sbjct: 507 PKRSHVKNGEVGRRRRHSPS----RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Query: 482 ----DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES-PLRIK 536
+ T ++P + YSPP+ + R S P K
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
Query: 537 MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ 596
AS S P+ ++ +P P R + +TK R + + H K RS + + PQ
Sbjct: 623 RRASPSPPPKRRVSHSPPP---KQRSSPVTKRRSPSLSSKHR-KGSSPSRSTRE-ARSPQ 677
Query: 597 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 656
+K S S + A + +R S +T ++PE ++I
Sbjct: 678 PNKRHSPSPRPRAPQT--SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE-PKKIK 734
Query: 657 ISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD-----------IDRRRKERS 705
+ S + R R + KK + ++ + + +
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
Query: 706 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS--- 762
+E G +K++K K +K+ K +K KHK+E+ + +++++ +P++ +
Sbjct: 795 SPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAAT 854
Query: 763 ---SREE----KESKKEREEE 776
++EE E KKE E E
Sbjct: 855 TTLAQEEPVAAPEPKKETESE 875
Score = 71.2 bits (173), Expect = 4e-12
Identities = 83/313 (26%), Positives = 121/313 (38%), Gaps = 49/313 (15%)
Query: 23 SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQ 82
S+ K R SRSRS++ SR+RSR ++R RR +R R R Y
Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-------------HRSRSRSY-- 309
Query: 83 GGGGRYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRR---SVSSQRSRSRSRRSYRSSRS 138
+ R SPRR S R R+P RR +RSRS RR RSS S
Sbjct: 310 ---------------SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354
Query: 139 PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----FEHD 194
SSS SSS S+SP K +K SP + + + P T H
Sbjct: 355 LSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS 414
Query: 195 PSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPMLST 250
P+ + N++ + + PG ++ SPSP P S S+
Sbjct: 415 PTP--QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
Query: 251 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR--SPAKTIAPQ 308
+ +A + + + Q+ S SGS + + + RR SP+++ +P
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532
Query: 309 NAPRDES---RGR 318
R + RGR
Sbjct: 533 PRKRQKETSPRGR 545
Score = 56.6 bits (135), Expect = 1e-07
Identities = 85/330 (25%), Positives = 115/330 (34%), Gaps = 33/330 (10%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSR-SRSRTYSRSRSRDRMYSRDYRRDYRNN 64
S S + + + S + R + R+ + SS S S + S R + ++ R
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
Query: 65 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 124
R R R GR R P RR S SP R R+P R
Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP----TPPPR 578
Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
R+ S R S SPR S YS SP KRR + K P SP
Sbjct: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP---SP------ 629
Query: 185 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSD 244
PK H P +SS + P LS+ SP S+S+ +
Sbjct: 630 -PPKRRVSHSPPPK----QRSSPVTKRRSPSLSSKHRKGSSP----------SRSTREAR 674
Query: 245 APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS-PIHHIPSRRSPAK 303
+P + HS P S P R G+ S + R SPS ++ PI + P K
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS--SPQRRQSPSPSTRPIRRVSRTPEPKK 732
Query: 304 -TIAPQNAPRDESRGRSSFYPDGGDQETAK 332
A +P+ R SS G + AK
Sbjct: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAK 762
Score = 53.1 bits (126), Expect = 1e-06
Identities = 86/386 (22%), Positives = 137/386 (35%), Gaps = 39/386 (10%)
Query: 3 RSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSS--RSRSRTYSRS---RSRDRMYSRD 56
R SSR K RS+S R +SRS S ++R S R R R++SRS R++ R S
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 116
+ + + P+ + + + K
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273
Query: 117 RRSVSSQRSRSRSRRSYRS-----SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171
R S RS+SRSR RS R S SRS SP + P +RR S ++T
Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRTPPRRM 332
Query: 172 EP-----QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP 226
P + SP++ + + S S+ + SS++S P P+ P
Sbjct: 333 PPPPRHRRSRSPVRRRRRS----------SASLSGSSSSSSSSRSRSP--------PKKP 374
Query: 227 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSP 286
P ++PP ++ S + + P+ +HSP S SP
Sbjct: 375 --PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
Query: 287 SQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESR 346
+ S + + K +P AP+ S D G + A +R +++
Sbjct: 433 GRTS--GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
Query: 347 VFLLDRGNTRDKEASKEKGSEKGRAE 372
D G++ E + K S E
Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGE 516
Score = 53.1 bits (126), Expect = 1e-06
Identities = 82/284 (28%), Positives = 112/284 (39%), Gaps = 42/284 (14%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRS-----RDRMYSRDY 57
RS S S R K S R RS S +R S S + R R+ R R S
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
Query: 58 RRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSP 115
RR + R P R Y + P RR S SP +R S S P
Sbjct: 587 RRRSPSPRRYSPPIQRR-----YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641
Query: 116 KRRS--VSSQRSRSRSR---------RSYRSSRSPRSSSSRSSSPY------SKSPVSKR 158
K+RS V+ +RS S S RS R +RSP+ + S SP S SP R
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
Query: 159 RGSQEKQTKKAEGEPQEESPLK--SKSQEEPKDTFEHDPS-ESIDEFNKSSATSGDIWPG 215
RG+ ++ P P++ S++ E K PS +S+ + S + SG P
Sbjct: 702 RGASSSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
Query: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259
+ + P PSP+ SQS S + +P + + TPS
Sbjct: 761 ------AKKPPAPPSPV---QSQSPSTNWSPAVPVKKAKSPTPS 795
Score = 37.4 bits (85), Expect = 0.065
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)
Query: 656 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR------HDIDRRRKERSKERG 709
++ P L +AG F E ++ K+ + + L D D+R KE KE
Sbjct: 104 ELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEE-KESS 162
Query: 710 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 769
K R S R++ ++P + + +R++ HSRS SPS EK+
Sbjct: 163 REKRERSRSPRRRKSRSPSPRRR----SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
Query: 770 K 770
K
Sbjct: 219 K 219
Score = 36.2 bits (82), Expect = 0.14
Identities = 99/459 (21%), Positives = 148/459 (32%), Gaps = 69/459 (15%)
Query: 488 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEV 547
+ +KKE Q++ EKL + K D EK + RE+ S P
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKR-DKEEKESSREKRERSRSPRRRKSRSPSP 182
Query: 548 KLKMAPVPLD----DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 603
+ + +PV + S P TK R S +K E +K P ++TS
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRS-PSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 604 SFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLR 663
S I + + E K + N + ++ T S R +S R SPS R
Sbjct: 242 SDILKVPK-PEPIPEP--KEPSPEKNSKKEKEKEKTRPRS-RSRSKSRSRTRSRSPSHTR 297
Query: 664 KHTRLAGEERVFKEENQKGDKKL---------RCDSADLRHDIDR----RRKERSKERGD 710
R R + + ++ R RH R RR+ S
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG 357
Query: 711 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 770
S S SS SR K P KR R + + +SP R + S
Sbjct: 358 SSSSSSSSRSRSPPKKPP--------------KRTSSPPRKTRRLSPSASPPRRRHRPSP 403
Query: 771 KEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRP 830
H + S R R + G + T K
Sbjct: 404 PATPPPKTRHSPTPQQS------------------NRTRKSRVSVSPGRTSGKVTKHKGT 445
Query: 831 KEEEWDPEYTPKSKKYFLHDDRDD--GVDYWAKRGRGRGTFQRGRGRFNFKKSGSS---- 884
++ E P PK +K L + +D G A + R ++R + + + SGSS
Sbjct: 446 EKRE-SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRR-QNQQSSSDSGSSSSSE 503
Query: 885 ---PKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
PK +H K +G V + RK +KE
Sbjct: 504 DERPKRSHVK---NGEVGRRRRHSPSRSASPSPRKRQKE 539
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 81.3 bits (199), Expect = 4e-15
Identities = 174/840 (20%), Positives = 314/840 (37%), Gaps = 95/840 (11%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD---YRN 63
R SRSKS SS SRS S++ K S +RSR+YSRS SR +SR Y R R
Sbjct: 680 RRSFSRSKSPYSGSSYSRS-SYTYSKSRSGSTRSRSYSRSFSRS--HSRSYSRSPPYPRR 736
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYR-PVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
RG R Y R R G YHR R P + R HSRS R +SP +R+V
Sbjct: 737 GRGKSRNYRSRSRSHG--------YHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQ 788
Query: 123 QRSRSRSRRSYRSSRSPRSSSS-RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
+ YR P + S + P K R +E + K E + +
Sbjct: 789 GETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKER-YREWERKYREWYEKYYKGYAA 847
Query: 182 KSQEEPKDTFEHDPSESIDEFN--KSSATSG--DIWPGLSAYDNSPRSPHSPSPIATPPS 237
+Q P E+ E N S T G + + G ++ + + P ++
Sbjct: 848 GAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDG 907
Query: 238 QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---------NGSSR----Y 284
+ + +A + H +H R G S G + SR
Sbjct: 908 HNQKDNTKSKEKESENAPGDGKGNKHK-KHRKRRKGEESEGFLNPELLETSRKSREPTGV 966
Query: 285 SPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT-GKFLKRFTD- 342
++ + +PS R A + + + +S D +++ K G KR D
Sbjct: 967 EENKTDSLFVLPS-RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDG 1025
Query: 343 ----EESRVFLLDRG------NTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE---- 388
++ + +G R++ E +K + E D S K+
Sbjct: 1026 SAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKIT 1085
Query: 389 SGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNR 448
+K + + +ET+ ++ + V D K + EE+ K K N+
Sbjct: 1086 GTPRKAHSKSAKEHQETKPVKE--EKVKKDYSKDVKSEKLTTKEEKAKKPNEK-----NK 1138
Query: 449 ESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKL--K 506
D E++ K +E G + S++ K E + + K++ + P+ K ++ K
Sbjct: 1139 PLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKME-PDTEKMDRTPEK 1197
Query: 507 DLFDYSPPLH---------KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLD 557
D S P K + + E + +E +++ +S + +VK K+
Sbjct: 1198 DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTG 1257
Query: 558 DSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLPQASKSTSESFIQHIVSLV 613
++L +ST V+K +E R++ IK + + + + + ++ ++
Sbjct: 1258 TEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTMEEYNNDNTAPAEDVIIMI 1314
Query: 614 HHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEER 673
+ ++ K + E K+T+ S+ K + + + PS + K+ E
Sbjct: 1315 QVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP- 1369
Query: 674 VFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG------SRESSGSRKQEKTP 727
E+ QK K + + ++H++ + S E+G +K +E+ RK P
Sbjct: 1370 --SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQP 1425
Query: 728 KDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 787
+ + K S+ + +S S + K+ R++ KT ++ +EYS
Sbjct: 1426 EKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDK--KTDYDTREYS 1483
Score = 76.3 bits (186), Expect = 1e-13
Identities = 147/749 (19%), Positives = 295/749 (39%), Gaps = 110/749 (14%)
Query: 103 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 149
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1051 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1107
Query: 150 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 203
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1108 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1160
Query: 204 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 248
+SS+ SP+ P + TP S S AP +
Sbjct: 1161 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1219
Query: 249 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 297
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1220 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1279
Query: 298 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 357
R+S KT D R + + TA + +S+ + D
Sbjct: 1280 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1325
Query: 358 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 417
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1326 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1382
Query: 418 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY-KLKETGYVVE 469
+ K+ A++ T++ K + + + S +E N +L E G
Sbjct: 1383 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1442
Query: 470 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 529
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1443 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1498
Query: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 589
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1499 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1549
Query: 590 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLNERFTSYQK----ATEE 641
D + + +KS ++ + H++ ++ KE LN T +K +
Sbjct: 1550 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1608
Query: 642 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDR 699
ST + P++ +S S L + T A E + E + + + ++ + S ++ D+
Sbjct: 1609 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1667
Query: 700 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 759
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1668 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1723
Query: 760 SPSSREEKESKKEREEEFKTHHEMKEYSG 788
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1724 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1752
Score = 75.1 bits (183), Expect = 3e-13
Identities = 189/886 (21%), Positives = 318/886 (35%), Gaps = 137/886 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDR--MYSRDYRR 59
GR SR++ SRS+S SRSRS + +RY SRSRS R +S ++ + + R
Sbjct: 737 GRGKSRNYRSRSRSHGYHRSRSRSPPY---RRYHSRSRSPQAFRGQSPNKRNVPQGETER 793
Query: 60 DYRNN-RGMRRPY---GYRGRG---RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS 112
+Y N R + PY Y GR R ++ R YR W ++ + G
Sbjct: 794 EYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYRE-WYEKYYKGYAAGAQPR 852
Query: 113 RSPKRRSVSSQR-----------SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS 161
S R + S +R +R R R Y +S RS + S+ P +S R G
Sbjct: 853 PSANRENFSPERFLPLNIRNSPFTRGR-REDYVGGQSHRSRNIGSNYP---EKLSARDGH 908
Query: 162 QEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
+K K++ + E +P K + K + K + G + P L
Sbjct: 909 NQKDNTKSKEKESENAPGDGKGNKHKKHR----------KRRKGEESEGFLNPELLETSR 958
Query: 222 SPRSP-----HSPSPIATPPSQ--SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
R P + + PS+ ++ D PM + + K+ + +
Sbjct: 959 KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 1018
Query: 275 GSVGNGSSRYSPSQN------SPIHHI-------PSRRSPAKTIAPQNAPRDESRGRSSF 321
N S S +N P + P P K + D ++ SS
Sbjct: 1019 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1078
Query: 322 YPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEK-----GRAEGEWE 376
D ++ T K + E + + K+ SK+ SEK +A+ E
Sbjct: 1079 QKD--EKITGTPRKAHSKSAKEHQETKPVKEEKVK-KDYSKDVKSEKLTTKEEKAKKPNE 1135
Query: 377 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEE-EG 435
+ LD +K K+K + D E+ + + V S +TE+ +
Sbjct: 1136 KNKPLDNKGEKR--KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1193
Query: 436 LKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI---TVKK 492
K K+SL + E K+ T E S TK+ ++ + S ++ VK
Sbjct: 1194 TPEKDKISLSAPAKKIKLNRETGKKIGST----ENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 493 ETQSPEQVKSEKLKDLFDYS-------PPLHKNLDA---------------REKSTFREE 530
+ + L DY+ P+ K+ + + + E+
Sbjct: 1250 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1309
Query: 531 SPLRIKMIAS----DSHRPEVKLKMAPVPLDDSNRPASLTKD-RLLASTLVHSVKKEQEF 585
+ I++ S D E + + P+ +PAS+ K+ S +V +KE E
Sbjct: 1310 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESE- 1368
Query: 586 RSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 645
K+ + +K S IQH V K T + ++ +K E
Sbjct: 1369 ----PSEKIQKFTKDVSHEIIQHEVK---SSKNSASSEKGKTKDRDYSVLEKENPEKRKN 1421
Query: 646 QKSPEIHRRID----------ISPS-----TLRKH--TRLAGEERVFKEENQKGDKKLRC 688
PE +D +S S T KH TR + + ++K D R
Sbjct: 1422 STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTRE 1481
Query: 689 DSADLRHD--IDRRRKERSKERGDSKGSRESSGSRKQEKTPK----DYKEYKSYKDDSKH 742
S+ R D + R++ S R S + + R++ PK D K KS S+
Sbjct: 1482 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSK--KSNSSPSRD 1539
Query: 743 KREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 788
++ DH +++ + P+ + +K K+RE+ KE SG
Sbjct: 1540 RKPHDH-KATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG 1584
Score = 70.1 bits (170), Expect = 9e-12
Identities = 209/986 (21%), Positives = 355/986 (36%), Gaps = 174/986 (17%)
Query: 22 RSRSRSHSRKKR-YSSRSRSR---TYSRSRS---RDRMYSRDYRRDYRNNRGMRRPYGYR 74
+ R RS SR K YS S SR TYS+SRS R R YSR + R + + PY
Sbjct: 677 KERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPY--- 733
Query: 75 GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS--QRSRSRS--- 129
PRRGR +SR+ + RS S RSRSRS
Sbjct: 734 ------------------------------PRRGRGKSRNYRSRSRSHGYHRSRSRSPPY 763
Query: 130 RRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 189
RR + SRSP+ + R SP +K V + +E + E P + + +D
Sbjct: 764 RRYHSRSRSPQ--AFRGQSP-NKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRD 820
Query: 190 TFEHDP--------SESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
FE + E +++ K A P + + SP P I P
Sbjct: 821 PFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPER-FLPLNIRNSPFTRGR 879
Query: 242 CSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301
D + H ++N S + + R G N S+ S+N+P
Sbjct: 880 REDY-VGGQSHRSRNIGSNYPEKLS---ARDGHNQKDNTKSKEKESENAP---------- 925
Query: 302 AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEAS 361
GD + K K KR EES FL +++
Sbjct: 926 ------------------------GDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSR 961
Query: 362 KEKGSEKGRAEG---------------EWEDQEALDYFSDKESGKQKFN--DSEGDDTEE 404
+ G E+ + + E D E++ + S E K++ + ++GD T+
Sbjct: 962 EPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKR 1021
Query: 405 TED------YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 458
D K Q K E +K + + K + +K+
Sbjct: 1022 KNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKD 1081
Query: 459 YKLKETGYVVERPSTTKDKHKEEDKNSERITVK---KETQSPE-QVKSEKLKDLFDYSPP 514
K+ TG + S + +H+E E K K+ +S + K EK K + + P
Sbjct: 1082 EKI--TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKP 1139
Query: 515 LHKNLDAREKSTFR-------EESPLRI-KMIASDSHRPEVKLKMAPVPLDDSNRPASLT 566
L + R++ T E S ++I K+ ++ +P K KM P D +
Sbjct: 1140 LDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEP---DTEKMDRTPE 1196
Query: 567 KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK---- 622
KD++ S +K +E + +K SE + S VK++ K
Sbjct: 1197 KDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK----LESTSSKVKQEKVKGKVR 1252
Query: 623 --------SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 674
S++ ++ TS + + +K+ I +T A + +
Sbjct: 1253 RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVII 1312
Query: 675 FKEENQ-KGDK-KLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 732
+ Q K DK + D++ + + ++ S+ + EK + ++
Sbjct: 1313 MIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEK 1372
Query: 733 YKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES--KKEREEEFKTHHEMKEYSGFA 790
+ + D H+ Q +SS +SAS +++ S +KE E+ K + ++ S
Sbjct: 1373 IQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLD 1432
Query: 791 GVSRPRGTFFRI-RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDP-EYTPKSKKYFL 848
++ +G F + + AR +T +++ R K+ ++D EY+ ++
Sbjct: 1433 RLNE-QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEK 1491
Query: 849 HD----------DRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP---KWTHD-KYQG 894
++ ++D K R ++G G + KKS SSP + HD K
Sbjct: 1492 NELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG--DSKKSNSSPSRDRKPHDHKATY 1549
Query: 895 DGIVEDEEETMENNEEKKDRRKEEKE 920
D +EE + KDR K E
Sbjct: 1550 DTKRPNEETKSVDKNPCKDREKHVLE 1575
Score = 47.0 bits (110), Expect = 8e-05
Identities = 82/434 (18%), Positives = 168/434 (38%), Gaps = 60/434 (13%)
Query: 96 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 142
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1389 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1448
Query: 143 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 202
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 1449 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1503
Query: 203 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 257
NK SA S N PR T S+ S+ S + H K T
Sbjct: 1504 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1553
Query: 258 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 317
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1554 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1605
Query: 318 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 374
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1606 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1664
Query: 375 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 428
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1665 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1719
Query: 429 RNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI 488
++ K K K K +++ ++ K K G VE + K KHK++ +
Sbjct: 1720 SAESQDSKKKKKKKEKKKHKKHKKHKKHK----KHAGTEVELEKSQKHKHKKKKSKKNKD 1775
Query: 489 TVKKETQSPEQVKS 502
K++ + ++VKS
Sbjct: 1776 KEKEKEKDDQKVKS 1789
Score = 45.8 bits (107), Expect = 2e-04
Identities = 66/300 (22%), Positives = 114/300 (38%), Gaps = 27/300 (9%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSR-----SRTYSRSRSRDRMYSRDY 57
+ N +S S SK S +R+ S K +R + +R YS S+ RD
Sbjct: 1437 QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTR 1496
Query: 58 RRD--YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP 115
R+D RN R + G G + P +R+ ++ +
Sbjct: 1497 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1556
Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSR----SSSPYSKSPVSKRRGSQEKQTKKAEG 171
+ +SV + R + + + SS ++ + P ++ + G +K T K +
Sbjct: 1557 ETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKP 1616
Query: 172 EPQEESPLKSK-SQEEPKDTFEHDPSESIDEFN---KSSATSGDIWPGL--SAYDNSPRS 225
+ S L S ++E + FE D +ES E N K +SG+I L + + S
Sbjct: 1617 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1676
Query: 226 PHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 285
+ + + S++ S HS+ + SHS S RS S S + S+ S
Sbjct: 1677 LDTAAVVQVGISRNQS----------HSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1726
Score = 40.0 bits (92), Expect = 0.010
Identities = 114/639 (17%), Positives = 224/639 (35%), Gaps = 83/639 (12%)
Query: 134 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 193
+ R+P S+P K +++ G + T+ + L+S S + ++ +
Sbjct: 1190 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 194 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
+ SS+T D + S SP+ ++ + ++
Sbjct: 1250 KVRRKVTGTEGSSST---------LVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1300
Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA--PQNAP 311
NT I +S S PI + S K ++ P N
Sbjct: 1301 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIV 1360
Query: 312 RDESRGRSSFYPDGGDQETAKTGKFLKRFTDE--------ESRVFLLDRGNTRDKEAS-- 361
+ YP+ + + K KF K + E ++G T+D++ S
Sbjct: 1361 K---------YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVL 1411
Query: 362 KEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGK 421
+++ EK + + E + LD +++ + K S+ T + D S A K
Sbjct: 1412 EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD------STRASSNK 1465
Query: 422 SFATASHRNTEEEGLKYKS-------------KVSLKGNRESDGF-----REEKNYKLKE 463
F + T+ + +Y S K S N++S REE++ K
Sbjct: 1466 DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1525
Query: 464 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE 523
TG + S+ K D + T K+ + + V KD + L+AR
Sbjct: 1526 TGDSKKSNSSPSRDRKPHDHKATYDT-KRPNEETKSVDKNPCKDREKHV------LEARN 1578
Query: 524 KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQ 583
+E S ++ I + PE +++ + ++ K +L S+ + S +
Sbjct: 1579 N---KESSGNKLLYILNP---PETQVEKEQIT-GQIDKSTVKPKPQLSHSSRLSSDLTRE 1631
Query: 584 EFRSIFDHIKLPQASKSTSESFI-----QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA 638
+ F+ P ++S SES + + ++ +K++ + A +L+
Sbjct: 1632 TDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1687
Query: 639 TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE------ERVFKEENQKGDKKLRCDSAD 692
+ S S R S S R H+ A ++ K++ +K KK +
Sbjct: 1688 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1747
Query: 693 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 731
+H E+S++ K + + +++EK D K
Sbjct: 1748 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1786
Score = 34.7 bits (78), Expect = 0.42
Identities = 77/417 (18%), Positives = 133/417 (31%), Gaps = 47/417 (11%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 66
+ + + K+ +Q S + + + S S+S +R+ + +D+ NR
Sbjct: 1413 KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD 1472
Query: 67 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 126
+ Y R RR ++ R S S + S S Q+++
Sbjct: 1473 KKTDYDTREYSSS------------------KRRDEKNELTRRKDSPSRNKDSASGQKNK 1514
Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
R R + S S SS + P + K+ P EE+ KS +
Sbjct: 1515 PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR-------PNEET--KSVDKNP 1565
Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
KD +H + E + +SG+ Y +P T S+ P
Sbjct: 1566 CKDREKH-----VLEARNNKESSGN----KLLYILNPPETQVEKEQITGQIDKSTVKPKP 1616
Query: 247 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN-------GSSRYSPSQNSPIHHIPSRR 299
LS + ++ + P+ + S S N S S I
Sbjct: 1617 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1676
Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD-RGNTRDK 358
+ R++S S P + + +G + + S D + + K
Sbjct: 1677 LDTAAVVQVGISRNQSHSSPSVSPS---RSHSPSGSQTRSHSSSASSAESQDSKKKKKKK 1733
Query: 359 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 415
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1734 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1790
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
+G S ++SHSS S SRS S S S++RSHS + S+ + + + +
Sbjct: 1685 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1744
Query: 59 RDYRNNRG 66
+ ++ + G
Sbjct: 1745 KKHKKHAG 1752
Score = 31.2 bits (69), Expect = 4.6
Identities = 46/184 (25%), Positives = 67/184 (36%), Gaps = 28/184 (15%)
Query: 671 EERVFKEENQKGDK--KLRCDSADLRHDIDRRRKER----SKERGDSKGSRESSGSRKQE 724
E+R KEE +K K + D A + + +KER S+ + GS S S
Sbjct: 644 EQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYS 703
Query: 725 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 784
K+ +SY + SRS S S S S P R + + ++H +
Sbjct: 704 KSRSGSTRSRSY--------SRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHR 755
Query: 785 EYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKE-----EEWDPEY 839
SR R +R R R+R A PN N + +E E P Y
Sbjct: 756 --------SRSRSPPYR-RYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPY 806
Query: 840 TPKS 843
K+
Sbjct: 807 DMKA 810
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 80.9 bits (198), Expect = 5e-15
Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 26/241 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
+ R HS RS+SRS+ R R+ S SR +R SRSR R++S+SRSR R S RR +
Sbjct: 242 KEEKRRHS-RSRSRSR---RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
RG R + R + + ++ S++P + S +R + RS S
Sbjct: 298 RERGRRSRSTSKTRDK--------------KKEDKEKKRSKTPPKSYSTAR--RSRSASR 341
Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
+R R RSR RS + PRS + S+SP S RR +EK+ K + ++E +
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRK----LSRSP-SPRRHKKEKKKDKDKERSRDERERSTS 396
Query: 183 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 242
+++ KD E D + + D YD+ PI T ++ C
Sbjct: 397 KKKKSKDK-EKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKEC 455
Query: 243 S 243
S
Sbjct: 456 S 456
Score = 51.2 bits (121), Expect = 4e-06
Identities = 66/302 (21%), Positives = 118/302 (39%), Gaps = 21/302 (6%)
Query: 545 PEVKLKMAPVPLDDSN-RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 603
P + +A + L +N SL D+LL L+ +V + + + + P TS
Sbjct: 161 PTLDPALAALGLPGANLNSQSLAADQLLK--LMSTV--DPKLNHVAAGLVSPSLKSDTSS 216
Query: 604 SFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLR 663
I+ + V Q SAA+ ++ K + +R +S RR +PS+ R
Sbjct: 217 KEIEEAMKRVREA--QSLISAAIEPDK------KEEKRRHSRSRSRSRRRR---TPSSSR 265
Query: 664 KHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ 723
H R R + + K + R S R R R RS+ ++ ++ +K+
Sbjct: 266 -HRRSRSRSR--RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR 322
Query: 724 EKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM 783
KTP K Y + + RE+ RS S + SP P S + K S+ K +
Sbjct: 323 SKTPP--KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK 380
Query: 784 KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKS 843
+ + R R T + + + + + + + + T +E+ +D E K
Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
Query: 844 KK 845
+K
Sbjct: 441 EK 442
Score = 51.2 bits (121), Expect = 4e-06
Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 24/231 (10%)
Query: 690 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS 749
SA + D ++ S+ R S+ R S SR + + + S + +
Sbjct: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293
Query: 750 RSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR 809
RS S S S+ + ++ KKE +E+ ++ K YS +R + R R R R+R
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS----TARRSRSASRERRRRRSR 349
Query: 810 GVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTF 869
S T K+P+ + +P +++ +D + + R
Sbjct: 350 ------------SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKD--------KDKERSRD 389
Query: 870 QRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
+R R KKS K K + D V+ + E+ D KE+KE
Sbjct: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/161 (21%), Positives = 65/161 (40%), Gaps = 11/161 (6%)
Query: 622 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 681
KS + R S ++ + +SP+ R S RK +R R KE+ +
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPR------SPKRKLSRSPSPRRHKKEKKKD 381
Query: 682 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 741
DK+ D + ++ K++ K+R R+S + ++ +DY E + D K
Sbjct: 382 KDKERSRDERERSTSKKKKSKDKEKDR-----ERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 742 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 782
K+E+ + S + + +S +E + HHE
Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHE 477
Score = 35.0 bits (79), Expect = 0.32
Identities = 35/165 (21%), Positives = 65/165 (39%), Gaps = 13/165 (7%)
Query: 615 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 674
H +E+ +S + + K + T KS RR + R+ +G
Sbjct: 296 HSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
Query: 675 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYK 734
K + K +KL + RH ++ K++ K++ S+ RE S S+K K+ K
Sbjct: 356 KKPRSPK--RKLSRSPSPRRH---KKEKKKDKDKERSRDERERSTSKK--------KKSK 402
Query: 735 SYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 779
+ D + K E D + + ++ KKE ++ +T
Sbjct: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIET 447
Score = 31.2 bits (69), Expect = 4.6
Identities = 45/268 (16%), Positives = 86/268 (32%), Gaps = 26/268 (9%)
Query: 119 SVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESP 178
++ + + R S SRS R + SS S+RR + ++++ P+
Sbjct: 236 AIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRS 295
Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQ 238
+ + T + + D+ K S T +Y + RS + S+
Sbjct: 296 HSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP------KSYSTARRSRSASRERRRRRSR 349
Query: 239 SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 298
S + S S +PS H + ++ S S + S
Sbjct: 350 SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRE 409
Query: 299 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 358
R + RD + + +E K ++ G+ + K
Sbjct: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP----------------IETGSPKTK 453
Query: 359 EASKEKGS----EKGRAEGEWEDQEALD 382
E S EKG+ + + G+ +E +D
Sbjct: 454 ECSVEKGTGDSLRESKVNGDDHHEEDMD 481
Score = 31.2 bits (69), Expect = 4.6
Identities = 54/248 (21%), Positives = 85/248 (34%), Gaps = 40/248 (16%)
Query: 246 PMLSTVHSAKNTPSQHSHSIQHSPERSGSG--------SVGNGSSRYSPSQNSPIHHIPS 297
P S +++ + SHS S RS S G S S +++
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
Query: 298 RRS--PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNT 355
+RS P K+ + R SR R G + K ++ + S
Sbjct: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSP-------RR 373
Query: 356 RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 415
KE K+K E+ R E E + DKE +++ ++S+ D + T DY
Sbjct: 374 HKKEKKKDKDKERSRDERERSTSKKKKS-KDKEKDRERKSESDKDVKQVTRDY------- 425
Query: 416 LADQGKSFATASHRNTEEEGL-KYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTT 474
+ EE+G K K K E+ + ++ K TG +
Sbjct: 426 --------------DEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVN 471
Query: 475 KDKHKEED 482
D H EED
Sbjct: 472 GDDHHEED 479
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 80.1 bits (196), Expect = 9e-15
Identities = 168/750 (22%), Positives = 277/750 (36%), Gaps = 78/750 (10%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRS--RSRDRMYSRDYRRDYR 62
+SR HSS S+S SS R R+KR S S RT + RS S R
Sbjct: 328 SSRHHSSSSQS---GSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQR 384
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
R R +GR ++ + +RRH R R R R
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSH---------DRRHERREDTRGKRDREKDSREERE 435
Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
S R +R R PR R + ++ RR ++ + + E ++ S +K
Sbjct: 436 YEQDQSSSRDHRDDREPRDGRDRRDARDTRD----RRELRDSRDMRDSREMRDYSR-DTK 490
Query: 183 SQEEPKDTFE-HDPSESIDEFNKSSATSGDIWPGLS-AYDNSPRSPHSPSPIATPPSQSS 240
+P+D+ D + D + + D +P S +Y + S S++
Sbjct: 491 ESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNE 550
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
S S+ S P PE+ GS GS S S NS H RS
Sbjct: 551 SRSEIRNDRMGRSRGRVPEL--------PEKGSRGS--RGSQIDSHSSNSNYHDSWETRS 600
Query: 301 --PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT--------------GKFLKRFTDEE 344
P + P+ RD++R SSF G+++ G+ + DE
Sbjct: 601 SYPERDRYPERDNRDQARD-SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDER 659
Query: 345 SRVFLLDRGNTRDKEASKEKGSEKGR-AEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 403
+DR + R E ++E+ E+ R E E E + D +KE ++ E +
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERER 719
Query: 404 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 463
E E R+ + D+ + R E E + + + + RE + RE + + +E
Sbjct: 720 EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARE 779
Query: 464 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSE---KLKDLFDYSPPLHKNLD 520
ER +DK K D E+ +E ++P E K + + SP ++
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 521 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN--RPASLTKDRLLASTLVHS 578
R RE SP + D + +L V +S P+ LT+DR
Sbjct: 840 RR-----REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR-------QG 887
Query: 579 VKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ--YFKSAAMTLNERFTSYQ 636
KE++ + + ++S+ E ++ VS V +EQ +S+ M + +Q
Sbjct: 888 RWKEEDRKP-----ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 637 KATEEHSTRQKSPEIHRRIDISPSTLRKHTR-LAGEERVFKEENQKGDKKLRCDSADLRH 695
E S R E ++ I ++K G ER E + + +
Sbjct: 943 SEDRETSDRAHD-ENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKK 1001
Query: 696 DIDRRRKERSKERGDSKGSRESSGSRKQEK 725
I+++RK K +GDS S E + + ++K
Sbjct: 1002 SIEKKRK---KSKGDSDISDEEAAQQSKKK 1028
Score = 74.3 bits (181), Expect = 5e-13
Identities = 179/873 (20%), Positives = 316/873 (36%), Gaps = 120/873 (13%)
Query: 109 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 168
R S+SPKR+S S S+ R + SP R+ SK+ SK++G +T
Sbjct: 213 RKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRN----SKTNQSKKKG---PRTPS 265
Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP-- 226
E+ L K +E+ K + I+E + G + + PRS
Sbjct: 266 PPPPIPEDIALGKKYKEKYK------VKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSP 319
Query: 227 ----HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS-QHSHSIQHSPERSGSGSVGNGS 281
HSP S S S S S K TPS + ++ RS S +
Sbjct: 320 AGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSL 379
Query: 282 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 341
S Q+ P H P R R + S + ++ GK +
Sbjct: 380 SSPQRKQSPPRHRSPMREK----------GRHDHERTSQSHDRRHERREDTRGKRDREKD 429
Query: 342 DEESRVFLLDRGNTRDKEASKEKGSEKGRAEG-EWEDQEALDYFSDKESGKQKFNDSEGD 400
E R + D+ ++RD +E + R + + D+ L D ++ + S
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR-- 487
Query: 401 DTEETEDYRQFRKSVLA-DQGKSFATASHRNTE---EEGLKY--------KSKVSLKGNR 448
DT+E+ D R R + A D +HR + EE Y S+ ++
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547
Query: 449 ESDGFREEKNYKL-KETGYVVERP--------STTKDKHKE----EDKNSERITVKKETQ 495
++ E +N ++ + G V E P + D H D R + + +
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 496 SPEQVKSEKLKD-LFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPV 554
PE+ ++ +D F+ D RE+ R SP+R + + R E + +
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQ-RPSSPIRHQGRNDELERDERREERRVD 666
Query: 555 PLDD------SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 608
+DD R +DR +E+E + + + + + +
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 609 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATE-EHSTRQKSPEIHRRIDISPSTLRKHTR 667
H +E+ ER +K E E R++ E R + R+ R
Sbjct: 727 RDRDRDHDRERE--------RERERDREKEREREREERERERERERERERERERERERAR 778
Query: 668 LAGEERVFK---EENQKGDKKLRCDSADLRHDIDRR-----RKERSKERGDSKGSRESSG 719
+ER + E+ KG R ++R D + R RK + + R + S S
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSP 838
Query: 720 SRKQEKTPKDYKEYKSYKD-DSKHK------REQDHSRSSSSSASPSSPSSREEKESKKE 772
R++E +P D Y S D + KH+ R Q+ S S + +E++ K E
Sbjct: 839 KRRREHSP-DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 773 REEEFKTHHEMKEYSGFAGVSRPR-GTFFRIRGRGRARGVFAGTNT----------GPNN 821
R+E + + E + + V + R T R RA+ + + N
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENK 957
Query: 822 SNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKS 881
QK+P +++ + + ++ + +DG + K+G+ + + ++ R KKS
Sbjct: 958 KKAKIQKKPIKKKKEDDV--GIERGNIETTSEDGQVFSPKKGQKKKSIEKKR-----KKS 1010
Query: 882 GSSPKWTHDKYQGDGIVEDEEETMENNEEKKDR 914
+GD + DEE ++ +++ R
Sbjct: 1011 -----------KGDSDISDEEAAQQSKKKRGPR 1032
Score = 59.3 bits (142), Expect = 2e-08
Identities = 133/668 (19%), Positives = 247/668 (36%), Gaps = 104/668 (15%)
Query: 309 NAPRDESRGRSSFY------PDGGDQETAKTGKF------LKRFTDEESRVFLLD--RGN 354
+ P +G SS Y P G +E K + KR T+E S + RG
Sbjct: 61 HGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGR 120
Query: 355 TRDKE---ASKEKGSEKGRAEGEWE------DQEALDY-FSDKESGKQKFNDSEGDDTEE 404
R+KE +KE+ E EWE D ++Y + + S + K + + +
Sbjct: 121 HREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKL 180
Query: 405 TEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKET 464
++ + R+ ++ + S + + L+ SK + + +K+ K
Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV 240
Query: 465 GYVV---ERPSTTKDKHKEEDKNS-------ERITVKKETQSPEQVKS---EKLKDLFDY 511
+ +R S T K+ + E I + K+ + +VK EK +D D
Sbjct: 241 SSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR 300
Query: 512 SPPLHKNLDAREKSTF-----REESPLRIKMIASDS--------HRPEVKLKMAPVPLDD 558
+ + R+K + SP+ + +S S H P + K P P
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSP--S 358
Query: 559 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 618
R + R + HS+ Q +S H + P K H E
Sbjct: 359 YQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRH-RSPMREKG-------------RHDHE 404
Query: 619 QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEE 678
+ +S ++R ++ T R+K R + S+ R H +++
Sbjct: 405 RTSQS-----HDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH----------RDD 449
Query: 679 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK------E 732
+ D + R D+ D R DRR S++ DS+ R+ S K+ + P+D + +
Sbjct: 450 REPRDGRDRRDARDTR---DRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHD 506
Query: 733 YKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGV 792
Y+ + H++E + S S + E+ S+ E E + + + G
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGR----NHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Query: 793 SRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDR 852
SR R +G +RG +++ +N + +++ R E D +Y D+R
Sbjct: 563 SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERD--------RYPERDNR 614
Query: 853 DDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKK 912
D D +R G + R R S + +D+ + D EE ++ ++++
Sbjct: 615 DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERD--ERREERRVDRVDDRR 672
Query: 913 DRRKEEKE 920
D R E++
Sbjct: 673 DERARERD 680
Score = 53.5 bits (127), Expect = 9e-07
Identities = 171/859 (19%), Positives = 293/859 (34%), Gaps = 130/859 (15%)
Query: 8 SHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGM 67
SHSS S +RS S+ + RY R +R +R S +R + RRD R R
Sbjct: 585 SHSSNSNYHDSWETRS---SYPERDRYPERD-NRDQARDSSFERRHGERDRRDNRE-RDQ 639
Query: 68 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR---------- 117
R R +GR R V +RR R+ R R R R +R
Sbjct: 640 RPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDR 699
Query: 118 -----RSVSSQRSRSRSR-------------RSYRSSRSPRSSSSRSSSPYSKSPVSKRR 159
R + +R+R R R R + R R + +R
Sbjct: 700 EREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERE 759
Query: 160 GSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAY 219
+E++ ++ +E + + K +E +D + D D K D P +
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRD-DRREKREEIREDRNPR-DGH 817
Query: 220 DNSP-----RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
D R+ SPSP +P + D+ ++ S ++ RS S
Sbjct: 818 DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 275 GS--VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAK 332
S + R+ P SRR + + + + D+ R ++ +
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDI 937
Query: 333 TGKFLK--RFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESG 390
G R T + + + + K K+K + G G E + E G
Sbjct: 938 IGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIE--------TTSEDG 989
Query: 391 KQKFNDSEGDDTEETEDYRQFRK--SVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNR 448
Q F+ +G + E R+ K S ++D+ + + R + K ++ N
Sbjct: 990 -QVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNG 1048
Query: 449 ESDGFREEKNYKLKETGYVVERPSTTKDKHK-EEDKNSERITVKKETQSPEQVKSEKLKD 507
++ G E+ K ++T + D+ + E +++ T T SP L
Sbjct: 1049 KN-GILEDSQKK-EDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSP-------LSS 1099
Query: 508 LFDYSPPLHKNLDAREKSTFR----------EESPLRIKMIAS------------DSHR- 544
L PP+ +T S + I A+ DSHR
Sbjct: 1100 LLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRK 1159
Query: 545 -----------PEVKLKMAP--VPLDD----------SNRPASLTKDRLLASTLVHSVKK 581
P V ++ A P+D SNR + + R ++ H
Sbjct: 1160 CHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGD 1219
Query: 582 EQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEE 641
+Q R H K+ S S + +K + + T ++R S
Sbjct: 1220 DQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRG--EPSRSTSSDRQDS-----RS 1272
Query: 642 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV---FKEENQKGDKKLRCDSADLRHDID 698
HS+R+ SPE R++ + RL +R + E ++ D + R D D
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP 1332
Query: 699 RRR-KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSAS 757
R R ++R +ER RE ++++ D + + D + R++D R+ SS
Sbjct: 1333 RNRDRDRLRER-----ERERERDKRRD---LDRERERLISDSVERDRDRDRDRTFESSQI 1384
Query: 758 PSSPSSREEKESKKEREEE 776
S + E + ER+ E
Sbjct: 1385 ESVKRCEAKLEGEHERDLE 1403
Score = 48.5 bits (114), Expect = 3e-05
Identities = 157/821 (19%), Positives = 281/821 (34%), Gaps = 148/821 (18%)
Query: 3 RSNSRSHSSRSKS--RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
R ++R R S R Q + R R++R R R R+R RDR RD R+
Sbjct: 631 RRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERE 690
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
R R R R R R+R R +R
Sbjct: 691 RERERERDR----------------------------EREKERELERERARERERER--- 719
Query: 121 SSQRSRSRSR-RSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
+R R R R R + R R + +R +E++ ++ +E +
Sbjct: 720 EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARE 779
Query: 180 KSKSQE-----EPKDTFEHDPSESIDEF--NKSSATSGDIWPGLSAYDNSPRSPHSPSPI 232
+ K +E E KD D E +E +++ D Y R+ SPSP
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRY----RNEGSPSPR 835
Query: 233 ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGS--VGNGSSRYSPSQNS 290
+P + D+ ++ S ++ RS S S + R+
Sbjct: 836 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 895
Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSF-------------YPDGGDQETAKTGKFL 337
P SRR + + + + D+ R ++ + D+ET+
Sbjct: 896 PERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS------ 949
Query: 338 KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKF--- 394
R DE + + + + K+ + G E+G E ED + FS K+ K+K
Sbjct: 950 DRAHDENKKKAKIQKKPIK-KKKEDDVGIERGNIETTSEDGQV---FSPKKGQKKKSIEK 1005
Query: 395 --NDSEGD-DTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESD 451
S+GD D + E +Q +K K T+EE ++ + G E
Sbjct: 1006 KRKKSKGDSDISDEEAAQQSKK-------KRGPRTPPITTKEELVEMCN--GKNGILEDS 1056
Query: 452 GFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDY 511
+E+ + V +R T+ +H + T T SP L L
Sbjct: 1057 QKKEDTAFSDWSDEDVPDRTEVTEAEH------TATATTPGSTPSP-------LSSLLPP 1103
Query: 512 SPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLL 571
PP+ +T +A+ + + + + S P + T
Sbjct: 1104 PPPVATATATTVPAT-----------LAATTAAAATSFSTSAITISTSATPTNTTN---- 1148
Query: 572 ASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM---TL 628
+T + + R+ + ++ P + I H +S+++
Sbjct: 1149 -NTFANEDSHRKCHRTRVEKVETPHVT----------IEDAQHRKPMDQKRSSSLGSNRS 1197
Query: 629 NERFTSYQKATEEHSTRQKSPEI---HRRIDISPSTLRKHTR---LAGEERVFKEENQKG 682
N TS + + + + +S + +R+ S S R+ T+ + GE + ++ ++G
Sbjct: 1198 NRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRG 1257
Query: 683 D--KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDS 740
+ + D D R RR S + S+ S R QE+ Y+ D
Sbjct: 1258 EPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQER--------DRYEHDR 1309
Query: 741 KHKREQDHSRSS--SSSASPSSPSSREE---KESKKEREEE 776
+ +RE+ +R A P +R+ +E ++ERE +
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD 1350
Score = 45.4 bits (106), Expect = 2e-04
Identities = 60/205 (29%), Positives = 78/205 (38%), Gaps = 39/205 (19%)
Query: 15 SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRS---RDRMYSRDYRRDYRNNRGMRRPY 71
SRS SS R SRSHS +R S S + +SRS S RDR+ RD R RR
Sbjct: 1260 SRSTSSDRQDSRSHS-SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT 1318
Query: 72 GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRS-PKRRSVSSQRSRSRSR 130
R R + W R R R R R R KRR + +R R S
Sbjct: 1319 RQREWDRDADKD-------------WPRNRDRDRLRERERERERDKRRDLDRERERLISD 1365
Query: 131 RSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG--EPQEESPLKSKSQEE-- 186
R R + S SQ + K+ E E + E L+S S++
Sbjct: 1366 SVERDRDRDRDRTFES--------------SQIESVKRCEAKLEGEHERDLESTSRDSLA 1411
Query: 187 -PKDTFEHD--PSESIDEFNKSSAT 208
K+ + D + +E NKS T
Sbjct: 1412 LDKERMDKDLGSVQGFEETNKSERT 1436
Score = 42.0 bits (97), Expect = 0.003
Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 35/225 (15%)
Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSR-----SRTYSRSRSRDRMYSRD 56
R +SRSHSSR S S SRS S + R R R R R +R R + RD
Sbjct: 1267 RQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRD 1326
Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 116
+D+ NR R R R R R RR R R +
Sbjct: 1327 ADKDWPRNRDRDR---LRER---------------------ERERERDKRRDLDRERE-R 1361
Query: 117 RRSVSSQRSRSRSR-RSYRSSR--SPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP 173
S S +R R R R R++ SS+ S + ++ + + S R S ++ + +
Sbjct: 1362 LISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDL 1421
Query: 174 QEESPLKSKSQEEPKDTFEHDPSES-IDEFNKSSATSGDIWPGLS 217
+ ++ E ++ E ES +D+ + + +G+ + +S
Sbjct: 1422 GSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPIS 1466
Score = 37.4 bits (85), Expect = 0.065
Identities = 45/194 (23%), Positives = 71/194 (36%), Gaps = 20/194 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
R + R + SRS R+H R++ SSR+ R SR+ SR + R+ R
Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREE--SSRTEIRNESRNESRSEI------RNDR 559
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
R R +G +G H Y W R S R R P+R +
Sbjct: 560 MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP-----ERDRYPERDNR 614
Query: 121 SSQRSRSRSRR-SYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEKQTKKAEGEPQE 175
R S RR R R R R SSP + + +E++ + + E
Sbjct: 615 DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDE 674
Query: 176 ESPLKSKSQEEPKD 189
+ + + +E ++
Sbjct: 675 RARERDRERERDRE 688
Score = 33.5 bits (75), Expect = 0.93
Identities = 99/514 (19%), Positives = 177/514 (34%), Gaps = 56/514 (10%)
Query: 435 GLKYKSKVSLKGNRES---DGF--------REEKNYKLKETGYVVERPSTTKDKHKEEDK 483
G KYK K +K E DG + EK K + T + S +H
Sbjct: 277 GKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSS 336
Query: 484 NSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDA----------REKSTFREESPL 533
S ++++ + SP + ++ +PPL ++ R++S R SP+
Sbjct: 337 QSGS-SIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPM 395
Query: 534 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI- 592
R K D R +D+ KD + EQ+ S DH
Sbjct: 396 REKG-RHDHERTSQSHDRRHERREDTRGKRDREKDSR------EEREYEQDQSSSRDHRD 448
Query: 593 -KLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEI 651
+ P+ + ++ + + S M + Y + T+E + S
Sbjct: 449 DREPRDGRDRRDARDTRD-------RRELRDSRDMRDSREMRDYSRDTKESRDPRDSRST 501
Query: 652 HRRIDISPSTLRKHTRLAGEERVFKEENQK-GDKKLRCDSADLRHDIDRRRKERSKERGD 710
D R R +E + EE++ G LR +S+ + R + RS+ R D
Sbjct: 502 RDAHDYRDREGRDTHR---KEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 558
Query: 711 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 770
G S R E K + + + DS H + S+ P E
Sbjct: 559 RMGR---SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRD 615
Query: 771 KEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRA-----RGVFAGTNTGPNNSNTT 825
+ R+ F+ H ++ + + R +GR R + + +
Sbjct: 616 QARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDER 675
Query: 826 FQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP 885
++R +E E D E + ++ DR+ + +R R R +R R R +
Sbjct: 676 ARERDRERERDRERERERER---ERDREREKERELERERAR---EREREREKERDRERDR 729
Query: 886 KWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEK 919
HD+ + D E+ E E+++R +E +
Sbjct: 730 DRDHDRERERERERDREKEREREREERERERERE 763
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 79.7 bits (195), Expect = 1e-14
Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%)
Query: 3 RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51
+S R+ SRS++R +SS S++RSRS SR++R SSRSRS R+ S+ + +
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 52 MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
R R+ + R R R R R H RR SRS R RS
Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949
Query: 112 SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168
S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR + +
Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009
Query: 169 AEGEP----QEESPLKSKSQEEP 187
P + +PL+ + P
Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032
Score = 79.0 bits (193), Expect = 2e-14
Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%)
Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50
RS +R SS+SKS RSQ+ SRSRSR R R S+SR R RS+SR+
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 51 RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106
R R RD R R R R R + R G R ++ R SR+P R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Query: 107 RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
R R+ RSR+P RRS S+RSR+ SRRS SR RS S +S SPV RR
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
+ + + + + S+ PK + D ++ + E K++A +
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068
Score = 68.2 bits (165), Expect = 3e-11
Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54
+ R S RS+S+ SS +SR S SR ++ SS+S RS+T SRSRSR R S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 55 RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
R R R + +R + R + + R + V R SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930
Query: 112 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Query: 159 RGSQEKQTKKAEGEPQEES 177
R + +++ + S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009
Score = 63.2 bits (152), Expect = 1e-09
Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S+ RS S RSKS S + S S SR ++ SS+S+S RS++R R SR RR R+
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
+ RGR R V + RSP+ RS+SR KR+ SS+
Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912
Query: 124 ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171
R+ SR RS+ SR RS S +S SP + R + + +
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972
Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230
P S S+ P PS + S I P +P R S S
Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031
Query: 231 PIATPPSQSSSCSDAP 246
PI S+SS +P
Sbjct: 2032 PIRRKRSRSSERGRSP 2047
Score = 50.1 bits (118), Expect = 1e-05
Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%)
Query: 102 SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144
SRS R S +S KR S S RSRSRSRR RSSRS +S
Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883
Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204
RS S + K R ++ +K ++++S+ + + H PS +
Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943
Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264
S I P + S RS +PS + PS+ S T TPS+ S +
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994
Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319
S R V S SP + P RR +++ + R RGRS
Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 42.7 bits (99), Expect = 0.002
Identities = 91/331 (27%), Positives = 130/331 (39%), Gaps = 53/331 (16%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59
+GR S S S +SR+ S RSR+ SR+ R SR RSRT S RSR+ R RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998
Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114
R +R + R R + R R R RR SRSP RR RSRS RS
Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046
Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
PKR + +++ +++ + + + P + P +EK KK+ G
Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102
Query: 175 EESPLKSK---SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
EE K K +E D + P S +E + + + P P P
Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEE------------PPFYHHPFKLSEPKP 2150
Query: 232 I----------ATPP-SQSSSCSDAPMLS-TVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
I TPP SQ + + P+ S + H K S + + + N
Sbjct: 2151 IFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDN 2210
Query: 280 GSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310
S PS+ I S R+ A+ +NA
Sbjct: 2211 VFSSNLPSEPVDISTAMSERALAQKRLSENA 2241
Score = 40.0 bits (92), Expect = 0.010
Identities = 72/313 (23%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 468 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 527
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 528 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 580
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 581 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 640
+++ S +AS+S+SE + + + VK+ + KS ++ + K +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFV--KVKDTHEKS------KKNKNRDKGEK 1814
Query: 641 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 700
E +++ + R S S+ K + E R + K R + RR
Sbjct: 1815 E---KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 701 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 760
R RS R S+G R S K++++PK ++S + K KR + A +
Sbjct: 1872 RSSRS--RSKSRG-RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 761 PSSREEKESKKER 773
PS R + R
Sbjct: 1925 PSRRSRSHTPSRR 1937
Score = 40.0 bits (92), Expect = 0.010
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 6/234 (2%)
Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169
RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
G + +S + + E S N+ + + P + ++P
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289
+ +S S S + T TPS+ S + S +PS+
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 290 SPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTGKFLKRFTD 342
+ RRS + + R R R S P + +++ G+ KR TD
Sbjct: 1999 RRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTD 2052
Score = 35.4 bits (80), Expect = 0.25
Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
Query: 636 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 695
++A+E S + EI ++ + +K+ E+ K ++ + R S++ +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835
Query: 696 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 755
R+R S+ R + S+ S + + + +S + SK + + S+
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 756 ASPSSPSSREEKESKKEREEEFKT 779
+ SRE K + + KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917
Score = 35.4 bits (80), Expect = 0.25
Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%)
Query: 676 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 735
K+ ++K K D + D + RSK S+ S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 736 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 795
++ ++ + R SS S S S SK++R+ K + +E SR
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913
Query: 796 RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 829
R R R +R + T + S + ++R
Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947
Score = 34.3 bits (77), Expect = 0.55
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
SR R P S K +K++ ++++ KK + +P EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145
Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
E D D ++ SA + ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 247 MLSTVHSAKNT 257
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.5
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 424 ATASHRNTEEEGLKYKSKVSLKGNRESD---------GFREEK--NYKLKETGYVVERPS 472
A AS R+ E + K + L G +++ G R+ + + + T + + S
Sbjct: 49 AAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKS 108
Query: 473 TTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR---EKSTFRE 529
KHK + K ++ KK + PE+ +S K K D + L + + E S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKFDSEPSAVAL 167
Query: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLASTLVHSVKKE 582
E P R + + P V L+ V ++ S +PA+ T + + ST V S + E
Sbjct: 168 ELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSE 227
Query: 583 Q 583
Q
Sbjct: 228 Q 228
Score = 31.2 bits (69), Expect = 4.6
Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 675 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 732
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 733 YKSYKDDSKHKREQD 747
DD E D
Sbjct: 139 KTKSHDDGNIDLESD 153
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 79.7 bits (195), Expect = 1e-14
Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%)
Query: 3 RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51
+S R+ SRS++R +SS S++RSRS SR++R SSRSRS R+ S+ + +
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 52 MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
R R+ + R R R R R H RR SRS R RS
Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949
Query: 112 SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168
S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR + +
Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009
Query: 169 AEGEP----QEESPLKSKSQEEP 187
P + +PL+ + P
Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032
Score = 79.0 bits (193), Expect = 2e-14
Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%)
Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50
RS +R SS+SKS RSQ+ SRSRSR R R S+SR R RS+SR+
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 51 RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106
R R RD R R R R R + R G R ++ R SR+P R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Query: 107 RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
R R+ RSR+P RRS S+RSR+ SRRS SR RS S +S SPV RR
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
+ + + + + S+ PK + D ++ + E K++A +
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068
Score = 68.2 bits (165), Expect = 3e-11
Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54
+ R S RS+S+ SS +SR S SR ++ SS+S RS+T SRSRSR R S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 55 RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
R R R + +R + R + + R + V R SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930
Query: 112 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Query: 159 RGSQEKQTKKAEGEPQEES 177
R + +++ + S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009
Score = 63.2 bits (152), Expect = 1e-09
Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S+ RS S RSKS S + S S SR ++ SS+S+S RS++R R SR RR R+
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
+ RGR R V + RSP+ RS+SR KR+ SS+
Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912
Query: 124 ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171
R+ SR RS+ SR RS S +S SP + R + + +
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972
Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230
P S S+ P PS + S I P +P R S S
Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031
Query: 231 PIATPPSQSSSCSDAP 246
PI S+SS +P
Sbjct: 2032 PIRRKRSRSSERGRSP 2047
Score = 50.1 bits (118), Expect = 1e-05
Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%)
Query: 102 SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144
SRS R S +S KR S S RSRSRSRR RSSRS +S
Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883
Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204
RS S + K R ++ +K ++++S+ + + H PS +
Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943
Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264
S I P + S RS +PS + PS+ S T TPS+ S +
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994
Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319
S R V S SP + P RR +++ + R RGRS
Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 29/210 (13%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59
+GR S S S +SR+ S RSR+ SR+ R SR RSRT S RSR+ R RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998
Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114
R +R + R R + R R R RR SRSP RR RSRS RS
Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046
Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
PKR + +++ +++ + + + P + P +EK KK+ G
Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102
Query: 175 EESPLKSK---SQEEPKDTFEHDPSESIDE 201
EE K K +E D + P S +E
Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132
Score = 40.0 bits (92), Expect = 0.010
Identities = 72/313 (23%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 468 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 527
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 528 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 580
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 581 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 640
+++ S +AS+S+SE + + + VK+ + KS ++ + K +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFV--KVKDTHEKS------KKNKNRDKGEK 1814
Query: 641 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 700
E +++ + R S S+ K + E R + K R + RR
Sbjct: 1815 E---KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 701 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 760
R RS R S+G R S K++++PK ++S + K KR + A +
Sbjct: 1872 RSSRS--RSKSRG-RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 761 PSSREEKESKKER 773
PS R + R
Sbjct: 1925 PSRRSRSHTPSRR 1937
Score = 40.0 bits (92), Expect = 0.010
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 6/234 (2%)
Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169
RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
G + +S + + E S N+ + + P + ++P
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289
+ +S S S + T TPS+ S + S +PS+
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 290 SPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTGKFLKRFTD 342
+ RRS + + R R R S P + +++ G+ KR TD
Sbjct: 1999 RRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTD 2052
Score = 35.4 bits (80), Expect = 0.25
Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
Query: 636 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 695
++A+E S + EI ++ + +K+ E+ K ++ + R S++ +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835
Query: 696 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 755
R+R S+ R + S+ S + + + +S + SK + + S+
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 756 ASPSSPSSREEKESKKEREEEFKT 779
+ SRE K + + KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917
Score = 35.4 bits (80), Expect = 0.25
Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%)
Query: 676 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 735
K+ ++K K D + D + RSK S+ S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 736 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 795
++ ++ + R SS S S S SK++R+ K + +E SR
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913
Query: 796 RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 829
R R R +R + T + S + ++R
Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947
Score = 34.3 bits (77), Expect = 0.55
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
SR R P S K +K++ ++++ KK + +P EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145
Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
E D D ++ SA + ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 247 MLSTVHSAKNT 257
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.5
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 424 ATASHRNTEEEGLKYKSKVSLKGNRESD---------GFREEK--NYKLKETGYVVERPS 472
A AS R+ E + K + L G +++ G R+ + + + T + + S
Sbjct: 49 AAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKS 108
Query: 473 TTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR---EKSTFRE 529
KHK + K ++ KK + PE+ +S K K D + L + + E S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKFDSEPSAVAL 167
Query: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLASTLVHSVKKE 582
E P R + + P V L+ V ++ S +PA+ T + + ST V S + E
Sbjct: 168 ELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSE 227
Query: 583 Q 583
Q
Sbjct: 228 Q 228
Score = 31.2 bits (69), Expect = 4.6
Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 675 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 732
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 733 YKSYKDDSKHKREQD 747
DD E D
Sbjct: 139 KTKSHDDGNIDLESD 153
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 79.3 bits (194), Expect = 1e-14
Identities = 70/183 (38%), Positives = 83/183 (45%), Gaps = 28/183 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRT-YSRSRSRDRMYSRDYRRDY 61
RS S RS+SR S SRSRSRS R RYS SR+ YSRSR YSR R+
Sbjct: 124 RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRES 183
Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR--SPRRGRSRSRSPKRRS 119
R GG Y GY N R+SR S R S RS
Sbjct: 184 RY--------------------GGSHYSSSGYS---NSRYSRYHSSRSHSKSGSSTSSRS 220
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP-VSKRRGSQEKQTKKAEGEPQEESP 178
S+ +S S +RRS SS S S SRSSS P VSKR+ ++K+ P+EE
Sbjct: 221 ASTSKS-SSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQ 279
Query: 179 LKS 181
+ S
Sbjct: 280 MSS 282
Score = 60.1 bits (144), Expect = 9e-09
Identities = 70/204 (34%), Positives = 88/204 (43%), Gaps = 29/204 (14%)
Query: 74 RGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRG-RSRSRSPKRRSVSSQRSRSRSRRS 132
RGR RG GG GR R R SRSPRR RSRSR P S RSRSRSR
Sbjct: 106 RGRSRG---GGYGRRSRS------YGRRSRSPRRRHRSRSRGP-----SCSRSRSRSR-- 149
Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
YR SR RS SRS PYS+S S+ S+ + + G S S S+
Sbjct: 150 YRGSRYSRSPYSRS--PYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSR-------- 199
Query: 193 HDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVH 252
+ S +KS +++ S ++ RS S + S+SSS + +P V
Sbjct: 200 YSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP--PRVS 257
Query: 253 SAKNTPSQHSHSIQHSPERSGSGS 276
K+ S SPE G S
Sbjct: 258 KRKSKSRSRSKRPPKSPEEEGQMS 281
Score = 40.0 bits (92), Expect = 0.010
Identities = 60/222 (27%), Positives = 83/222 (37%), Gaps = 57/222 (25%)
Query: 100 RHSRSPRRGRSRSRSPKRRSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
R + RGRSR RRS S +RSRS RR SR P S SRS S Y
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRY-------- 150
Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 218
RGS+ ++ P SP S
Sbjct: 151 RGSRYSRS------PYSRSPYSR-----------------------------------SR 169
Query: 219 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 278
Y RSP+S S S S + ++ +S ++ HS S + RS S S
Sbjct: 170 YS---RSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKS 226
Query: 279 NGSSRYSPSQNSPIHHIPSR-RSPAKTIAPQNAPRDESRGRS 319
+ + R S++S + SR RS + T +P + +S+ RS
Sbjct: 227 SSARR---SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRS 265
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 79.0 bits (193), Expect = 2e-14
Identities = 72/204 (35%), Positives = 89/204 (43%), Gaps = 42/204 (20%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
MGR SR + RS SR +S SRSRSRS S K+ S R R SRSR RDR R RD
Sbjct: 1 MGRE-SRHYRKRSASRGRSGSRSRSRSPSDKR--SKRGDDRR-SRSRDRDRRRERSRSRD 56
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
R +R R R R R R R R RSRS RR
Sbjct: 57 KRRSRSRDRKRLRRSRSR-----------------------ERDRSRERRRSRSRDRR-- 91
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
RSRSR RR SRSSSP +KS ++ R +++T E +++
Sbjct: 92 -RSRSRSRGRR------------SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD 138
Query: 181 SKSQEEPKDTFEHDPSESIDEFNK 204
K E+ KD D ++ +E K
Sbjct: 139 DKEDEKEKDAGNFDQNKLEEEMRK 162
Score = 61.2 bits (147), Expect = 4e-09
Identities = 58/205 (28%), Positives = 81/205 (39%), Gaps = 27/205 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
RS SR R + R +S SR + RS SR ++ RSRSR RSR R R SRD RR
Sbjct: 39 RSRSRD---RDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS 95
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
+RG R G + NR S+ G S+ K+
Sbjct: 96 RSRGRRSRSSSPGNKS---------------KKTENRSRSKEKTDGGESSKEKKKDKDDK 140
Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ---EESPL 179
+ + + ++ ++ R K V K R Q K+ + GE + EE
Sbjct: 141 EDEKEKDAGNFDQNKLEEEMRKR------KERVEKWREEQRKKAMENIGELKKEIEEMKQ 194
Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204
K E D E DP+E+ E N+
Sbjct: 195 GKKWSLEDDDDDEDDPAEAEKEGNE 219
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/208 (26%), Positives = 85/208 (40%), Gaps = 28/208 (13%)
Query: 714 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 773
SR SGSR + ++P D K K D R++D R S S SR+ K ++ R
Sbjct: 14 SRGRSGSRSRSRSPSD-KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSR 72
Query: 774 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 833
E E + SR R R R R R+RG + +++ N S T + +E
Sbjct: 73 SRERDRSRERRR-------SRSRD---RRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 834 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSS-PKWTHDKY 892
+ D + K KK D+DD D ++ + G F + + +K KW
Sbjct: 123 KTDGGESSKEKK----KDKDDKED---EKEKDAGNFDQNKLEEEMRKRKERVEKWRE--- 172
Query: 893 QGDGIVEDEEETMENNEEKKDRRKEEKE 920
E ++ MEN E K +E K+
Sbjct: 173 ------EQRKKAMENIGELKKEIEEMKQ 194
Score = 47.0 bits (110), Expect = 8e-05
Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 13/160 (8%)
Query: 631 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLR 687
R S +++ R +S + RR + S S ++ +R +R+ + +++ D+ + R
Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRR 84
Query: 688 CDSADLRHDIDRRRKERSKERGDSKGSRESSG-SRKQEKTP--KDYKEYKSYKDDSKHKR 744
S D R R R RS+ S+++ SR +EKT + KE K KDD + ++
Sbjct: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
Query: 745 EQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 784
E+D + EE +KER E+++ K
Sbjct: 145 EKDAGNFDQNKL-------EEEMRKRKERVEKWREEQRKK 177
Score = 37.7 bits (86), Expect = 0.049
Identities = 27/115 (23%), Positives = 45/115 (39%), Gaps = 2/115 (1%)
Query: 663 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR-RRKERSKERGDSKGSRESSGSR 721
RK + G DK+ + DR RR+ERS+ R D + SR R
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSR-DKRRSRSRDRKR 67
Query: 722 KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 776
+ ++ + + R + SRS + SSP ++ +K + R +E
Sbjct: 68 LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Score = 35.8 bits (81), Expect = 0.19
Identities = 67/313 (21%), Positives = 117/313 (37%), Gaps = 67/313 (21%)
Query: 297 SRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNT 355
SR +++ +P N + + E+R RS DGG+ K K+ D++ D GN
Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEK-----KKDKDDKEDEKEKDAGNF 151
Query: 356 RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 415
+ +E K R E +W +++ ++K ++ G+ +E E+ +Q +K
Sbjct: 152 DQNKLEEEMRKRKERVE-KWREEQ-----------RKKAMENIGELKKEIEEMKQGKKWS 199
Query: 416 LADQGKSF---ATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 472
L D A A E EG + D + EE ++K+
Sbjct: 200 LEDDDDDEDDPAEAEKEGNEMEGEELD---------PLDAYMEEVKEEVKKFNM-----R 245
Query: 473 TTKDKHKEEDKNSERIT--VKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 530
+ K E K+ +T V T V S+K K + + DA E S+ EE
Sbjct: 246 SVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKK-----GELMENDQDAMEYSSEEEE 300
Query: 531 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 590
L+ + TK R L + H + + FR F
Sbjct: 301 VDLQTALTGYQ------------------------TKQRKLLEPVDHGKIEYEPFRKNF- 335
Query: 591 HIKLPQASKSTSE 603
++++P+ +K + E
Sbjct: 336 YVEVPELAKMSQE 348
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 79.0 bits (193), Expect = 2e-14
Identities = 190/835 (22%), Positives = 317/835 (37%), Gaps = 145/835 (17%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRT-------YSRSRSRDRMYSR 55
RS SRS SRS SRS + SRS + SHSR + SSRS SR SRS S + S
Sbjct: 691 RSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSD 750
Query: 56 DYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP 115
D RR R R G V +++HS S + S+
Sbjct: 751 DGRRAKRRLRS-----------------------SGKKNSVSHKKHSSSSEK-TLHSKYV 786
Query: 116 KRRSVSS---QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE 172
K R SS + S SRS Y SS S +SS + S K +++G E+ K E
Sbjct: 787 KGRDRSSCVRKYSESRSSLDY-SSDSEQSSVQATQSAQEK----EKQGQMERTHNKQEKN 841
Query: 173 PQEESPLKSKSQEE----PKDTFEHDPSESIDEFNKSSAT--SGDIW--PGLSAYDNSPR 224
EE KSKS+ E K T + + S+ + +K +G W S D +
Sbjct: 842 RGEE---KSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKN 898
Query: 225 SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY 284
S + P + ++ +S +H K P+ S + P+ +G+ +
Sbjct: 899 SKNDSHPSSDKEEGEATSDSESEVSEIH-IKVKPTTKSSTNTSLPDDNGAWKSSKQRTST 957
Query: 285 SPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEE 344
S S+ S + + +RG+ + G + LKR ++
Sbjct: 958 SDSEGS------------------CSNSENNRGKPQKHKHGSKEN-------LKREHTKK 992
Query: 345 SRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDT 402
+ L + + + K +++ + GE E++E D +ES ++K SE ++T
Sbjct: 993 VKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV--SENNET 1050
Query: 403 EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLK 462
+ ++ + KS D T + + ++ K SK+S+ + EE L+
Sbjct: 1051 IK-DNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALN---TEENVACLQ 1106
Query: 463 ETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR 522
+V E + + D N E T + SP +V+ + SP + LD
Sbjct: 1107 NIQHVEESVPNGVEDVLQTDDNMEICT--PDRSSPAKVE--------ETSPLGNARLDTP 1156
Query: 523 E-----KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------SLTKDRLL 571
+ K E P + +++ +S E K+ + V DS+ + S K +
Sbjct: 1157 DINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGESTGKKEVA 1214
Query: 572 ASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE- 630
+ ++ + K+ + ++ P A +TS + +++ V +K Q + + N+
Sbjct: 1215 EKSQINLIDKKWKPLQGVGNLAAPNA--ATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKV 1272
Query: 631 ----RFTSYQKA--------TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEE 678
F +K +E S+ +++P R D S S +R E +
Sbjct: 1273 RPGSLFDEVRKTARLNRRPRNQESSSDEQTPS---RDDDSQSRSPSRSRSKSETK----- 1324
Query: 679 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKD 738
+ R S H R R S R S S G + +T Y+SYK
Sbjct: 1325 -----SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKS 1379
Query: 739 DSKHKREQDHSRSSSSSASPSSPS------SREEKESKKEREEEFKTHHEMKEYS 787
R SRS SSS P S S S + + R + ++H + Y+
Sbjct: 1380 ----HRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYN 1430
Score = 74.7 bits (182), Expect = 4e-13
Identities = 189/859 (22%), Positives = 313/859 (36%), Gaps = 139/859 (16%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN 64
NS S S S SS S RS SR R SRS SR+Y+RSRS +SR
Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSR--SRSYSRSYTRSRSLASSHSRS-------- 719
Query: 65 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 124
R R R Y Y + + R+ RR RS S K+ SVS ++
Sbjct: 720 ----RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS---SGKKNSVSHKK 772
Query: 125 SRSRSRRSY---------RSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKKAEGEPQ 174
S S ++ RSS + S SRSS YS S S + +Q Q K+ +G+ +
Sbjct: 773 HSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQME 832
Query: 175 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 234
+ K++ E K E + S K + LS + + P + +
Sbjct: 833 RTHNKQEKNRGEEKSKSERECPHSKKRTLKEN---------LSDHLRNGSKPKRKNYAGS 883
Query: 235 P-PSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 293
S+S+S D KN+ + SH E + S S+ S IH
Sbjct: 884 KWDSESNSERDV--------TKNSKND-SHPSSDKEEGEATSD--------SESEVSEIH 926
Query: 294 HI--PSRRSPAKTIAPQ-NAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLL 350
P+ +S T P N S+ R+S G ++ + + S+ L
Sbjct: 927 IKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLK 986
Query: 351 DRGNTRDKEASKEKGSEKGRAE--------------GEWEDQEALDYFSDKESGKQKFND 396
+ KE K K +K +A GE E++E D +ES ++K
Sbjct: 987 REHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV-- 1044
Query: 397 SEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREE 456
SE ++T + ++ + KS D T + + ++ K SK+S+ + EE
Sbjct: 1045 SENNETIK-DNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNT---EE 1100
Query: 457 KNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLH 516
L+ +V E + + D N E T + SP +V+ + SP +
Sbjct: 1101 NVACLQNIQHVEESVPNGVEDVLQTDDNMEICT--PDRSSPAKVE--------ETSPLGN 1150
Query: 517 KNLDARE-----KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------SL 565
LD + K E P + +++ +S E K+ + V DS+ + S
Sbjct: 1151 ARLDTPDINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGEST 1208
Query: 566 TKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAA 625
K + + ++ + K+ + ++ P A+ TS + +++ V +K Q +
Sbjct: 1209 GKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAA--TSSAVEVKVLTTVPEMKPQGLRIEI 1266
Query: 626 MTLNE-----------------RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRL 668
+ N+ R Q+++ + T + + R SPS R +
Sbjct: 1267 KSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSR---SPSRSRSKSET 1323
Query: 669 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER-------SKERGDS----KGSRES 717
R + R ++ R R + R ++ R S K R S
Sbjct: 1324 KSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTS 1383
Query: 718 SGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE------SKK 771
S SR + + + +SY DS + R + SRS S + S S
Sbjct: 1384 SRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDS 1443
Query: 772 EREEEFKTHHEMKEYSGFA 790
E + + H E S ++
Sbjct: 1444 ESDRSYSHHRSPSESSRYS 1462
Score = 71.2 bits (173), Expect = 4e-12
Identities = 206/1028 (20%), Positives = 351/1028 (34%), Gaps = 198/1028 (19%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSR-----------SRSHSRKKRYSSRSRSRTYSRSRSR 49
M S R SSRS S S S R S +HS + Y S+S S++YSR SR
Sbjct: 475 MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR 534
Query: 50 DRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR 109
R S+ R R + HR +R S+SPR +
Sbjct: 535 SRTASKS---------------SSHSRSRSKSRSSSKSGHR--------KRASKSPR--K 569
Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
+ S+ + + V ++ R+ ++ P + + P S SP R +K K +
Sbjct: 570 TASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPS 629
Query: 170 EGEPQEESP-----LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224
QE L +S + E S S + K+S + + S +S
Sbjct: 630 YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSD-RSSES 688
Query: 225 SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS----IQHSP-ERSGS-GSVG 278
SP S S + S S S + + L++ HS +PS SHS HS RS S S+
Sbjct: 689 SPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSIS 748
Query: 279 NGSSR------YSPSQNSPIHHIPSRRSPAKTIAPQ--------NAPRDESRGRSSF-YP 323
+ R S + + + H S KT+ + + R S RSS Y
Sbjct: 749 SDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYS 808
Query: 324 DGGD----------QETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK----------- 362
+ QE K G+ + +E +RG + K +
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNKQEK-----NRGEEKSKSERECPHSKKRTLKE 863
Query: 363 ---------EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRK 413
K K A +W+ + + K S S+ ++ E T D
Sbjct: 864 NLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Query: 414 SVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDG--FREEKNYKLKETGYVVERP 471
+ + ++++ + ++ +KS +S+G E N R
Sbjct: 924 EIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENN-----------RG 972
Query: 472 STTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 527
K KH ++ ++++++ K + + ++ K+ K K F + PPL +
Sbjct: 973 KPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEE------- 1025
Query: 528 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRS 587
EE + K + +S +V + + S +D V +F
Sbjct: 1026 -EEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTK 1084
Query: 588 IFDHIKLPQASKSTSESF-----IQHI-VSLVHHVKEQYFKSAAMTLNERFTSYQKATEE 641
+ + + +T E+ IQH+ S+ + V++ M + S EE
Sbjct: 1085 DDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEE 1144
Query: 642 HS----TRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGD-KKLRCDSADLRHD 696
S R +P+I+ + +T + +E E G+ K SA L
Sbjct: 1145 TSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASA 1204
Query: 697 IDRRRKERSKERG-----DSK-----------------------------GSRESSGSRK 722
+ K+ E+ D K + G R
Sbjct: 1205 GESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRI 1264
Query: 723 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS----SREEKESKKEREEEFK 778
+ K+ + + + K R R+ SS+ +PS S+ S+ + E K
Sbjct: 1265 EIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETK 1324
Query: 779 THHEMK--EYSGFAGVSRPRGTFFRIR--GRGRARGVFAGTNTGPNNSN--------TTF 826
+ H + YS SR + +R R R R+RG ++ T +S+ T+
Sbjct: 1325 SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSS 1384
Query: 827 QKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRG----RGRFNFKKSG 882
+ R + +DP +S Y D + R R R QR RGR ++S
Sbjct: 1385 RSRSRSSSYDPHSRSRSYTY----------DSYYSRSRSRSRSQRSDSYHRGRSYNRRSR 1434
Query: 883 SSPKWTHD 890
S + D
Sbjct: 1435 SCRSYGSD 1442
Score = 70.5 bits (171), Expect = 7e-12
Identities = 65/178 (36%), Positives = 84/178 (47%), Gaps = 20/178 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S+ ++ S S+S+S SRSRS+S ++ + R+RS +YS SRSR R + YR
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSETKSRH---RTRSVSYSHSRSRSRSSTSSYRS---- 1350
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS-- 121
R Y R R RG+Y G R YR + R S S R RS S P RS S
Sbjct: 1351 -----RSYS-RSRSRGWYSRGRTRSRSSSYRSYKSHRTS-SRSRSRSSSYDPHSRSRSYT 1403
Query: 122 --SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 177
S SRSRSR RS RS RS + S+S S S+ ++ P E S
Sbjct: 1404 YDSYYSRSRSRS--RSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 67.8 bits (164), Expect = 4e-11
Identities = 154/714 (21%), Positives = 265/714 (37%), Gaps = 93/714 (13%)
Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
+ R S S S + S S SS S + + P KR + K+ +E
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
EP+ + + K E DT E +S + K +I P +
Sbjct: 247 -EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP----VPENRFLLRRDM 301
Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ-------HSPERSGSGSVG--NGS 281
P+ T + AP++S K + S+ I+ H+P RS S S + S
Sbjct: 302 PVVTAEPEPKIPDVAPIVS---DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 282 SRYSPSQNSPIHHIPSRRSPA--------KTIAPQNAPRDE----SRGRS-SFYPDGGDQ 328
S P + + + R P+ K P ++ DE R RS S+ D
Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDL 418
Query: 329 ETAK-TGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDK 387
TA+ +G KR +E +V +G + K + K ++K R + SD
Sbjct: 419 STARHSGHHKKR--RKEKKVKHKKKGK-KQKHCRRHKQTKKRR----------ILIPSDI 465
Query: 388 ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTE-EEGLKYKSKVSLKG 446
ES K + E R R S L+ S S + + + L + S+ S +
Sbjct: 466 ESSKSSTRRMKSSCDRE----RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS 521
Query: 447 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 506
S + + T S ++ K + K+ R K+ ++SP + S+
Sbjct: 522 KSHSQSY--SRGSSRSRTASKSSSHSRSRSKSRSSSKSGHR---KRASKSPRKTASQ--- 573
Query: 507 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS--HRPEVKLKMAPVPLDDSNRPAS 564
L +N + + PLR M +++ +P V + +PL DS P+
Sbjct: 574 --------LSENKPVKTE-------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSR 618
Query: 565 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 624
+ S ++ QE ++ H+ LP S + + + S +H +E+ +S
Sbjct: 619 WKPGQ---KPWKPSYERIQEMKAKTTHL-LPIQSTYSLANIKETGSSSSYHKREKNSESD 674
Query: 625 AMTLNERFTSYQKATEEHSTR-----QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 679
T ++ Y + E S R +S R S S H+R N
Sbjct: 675 QST----YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRN 730
Query: 680 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKD--YKEYKSYK 737
+ D +C + I R+K R S G + S +K + + + +Y +
Sbjct: 731 KYSDHS-QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGR 789
Query: 738 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE---FKTHHEMKEYSG 788
D S R+ SRSS +S S SS + +S +E+E++ +TH++ ++ G
Sbjct: 790 DRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRG 843
Score = 61.6 bits (148), Expect = 3e-09
Identities = 57/144 (39%), Positives = 66/144 (45%), Gaps = 11/144 (7%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
RS S SHS RS+SRS +SS RSRS+SR + SR RT SRS S R Y+
Sbjct: 1330 RSVSYSHS-RSRSRSSTSSY-RSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHRT 1382
Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
++R R Y R Y R R R RS R RS + + RS S
Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR----SRSQRSDSYHRGRSYNRRSRSCRS 1438
Query: 123 QRSRSRSRRSYRSSRSPRSSSSRS 146
S S S RSY RSP SS S
Sbjct: 1439 YGSDSESDRSYSHHRSPSESSRYS 1462
Score = 59.3 bits (142), Expect = 2e-08
Identities = 164/792 (20%), Positives = 300/792 (37%), Gaps = 103/792 (13%)
Query: 2 GRSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
GR R H+ SRS S S S + H +++ R R Y R S ++ D
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEM----QRLRAY-RPPSGEKWSKGDKL 389
Query: 59 RDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRGGY------RPVWNRRHSRSPRRGR 109
D ++R R R R GYY H G + + V +++ + + R
Sbjct: 390 SDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCR 449
Query: 110 SRSRSPKRR-----SVSSQRSRSRSRRS----YRSSRSPRSSSSRSSS-PYSKS--PVSK 157
++ KRR + S +S +R +S RSSRS SS SS +SKS V
Sbjct: 450 RHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQS 509
Query: 158 RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 217
+ + +++ Q S S+S+ K + H S S ++SS+ SG
Sbjct: 510 SLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS-SHSRSRS---KSRSSSKSG------- 558
Query: 218 AYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQH--SHSIQHSPERSGSG 275
+ R+ SP A+ S++ P+ +T+ +N Q + +I P
Sbjct: 559 ---HRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPL----- 610
Query: 276 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGK 335
S SR+ P Q P + S + I A S Y +ET +
Sbjct: 611 SDSPPPSRWKPGQK------PWKPS-YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSS 663
Query: 336 FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFN 395
+ KR + ES + + R E+S S R+ S S + +
Sbjct: 664 YHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSR------------SYSRSYTRSRS 711
Query: 396 DSEGDDTEETEDYRQFRKSVLADQGKSFATASHRN-TEEEGLKYKSKVSLKGNRESDGFR 454
+ + R ++ +D + ++S+ + + ++G + K ++ G + S +
Sbjct: 712 LASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHK 771
Query: 455 E--EKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYS 512
+ + K + YV R ++ + E ++S + E S + +S + K +
Sbjct: 772 KHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK---EKQ 828
Query: 513 PPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLA 572
+ + + +EK+ E+S S+ P K + L D R S K + A
Sbjct: 829 GQMERTHNKQEKNRGEEKS-------KSERECPHSKKRTLKENLSDHLRNGSKPKRKNYA 881
Query: 573 STLVHS-VKKEQEFRSIFDHIKLPQASKSTSE--SFIQHIVSLVHHVKEQYFKSAAMTLN 629
+ S E++ + P + K E S + VS +H + KS+ T
Sbjct: 882 GSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSL 941
Query: 630 ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD 689
K++++ ++ S + + +KH + +E + +E +K +KL+
Sbjct: 942 PDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKH-KHGSKENLKREHTKKVKEKLK-G 999
Query: 690 SADLRHDIDRRR------------KERSKERGDSKGSRESSGSRKQE--KTPKD--YKEY 733
D +H +R+ +E +E D + ++ES + E +T KD K
Sbjct: 1000 KKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTE 1059
Query: 734 KSYKDDSKHKRE 745
KS ++D K +
Sbjct: 1060 KSSEEDLSGKHD 1071
Score = 52.4 bits (124), Expect = 2e-06
Identities = 165/822 (20%), Positives = 282/822 (34%), Gaps = 134/822 (16%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
+ S S S S S SSS S S S +R R R RS+ R + RN
Sbjct: 193 THSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRN-- 250
Query: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRS 125
+H+ +P+ RS + ++RSV S S
Sbjct: 251 ----------------------------------KHAMNPKGHSERSDTNEKRSVDS--S 274
Query: 126 RSRSRRSYRSSRSPRSSSSR----------SSSPYSKSP-----VSKRRGSQEKQTKKAE 170
R + R P +R ++ P K P VS ++ S K +K +
Sbjct: 275 AKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIK 334
Query: 171 GEP--QEESPLKSK--SQEEPKDTFEHDP--SESIDEFNKSSATSGDIW--------PGL 216
G + +P +S+ S+ + D+ E P E + SG+ W P
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCS 394
Query: 217 SAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV-HSAKNTPSQHSHSIQHSPERSGSG 275
S +D S S S S + SD LST HS + + ++H + G
Sbjct: 395 SRWDERSLSQRSRS-----WSYNGYYSD---LSTARHSGHHKKRRKEKKVKHKKK----G 442
Query: 276 SVGNGSSRYSPSQNSPI---HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAK 332
R+ ++ I I S +S + + SR S ++ +K
Sbjct: 443 KKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSK 502
Query: 333 TGKFLKRFTDEESRVFL--------LDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYF 384
+ K ++ SR RG++R + ASK + R++ +
Sbjct: 503 SDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKR 562
Query: 385 SDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVS- 443
+ K K SE + R ++ ++ N L S
Sbjct: 563 ASKSPRKTASQLSENKPVKT----EPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSR 618
Query: 444 -LKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKS 502
G + E +T +++ ST + +E +S +++ +Q
Sbjct: 619 WKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTY 678
Query: 503 EKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRP 562
K D S P ++ +R +S R S R + +AS R +P S
Sbjct: 679 SKYSDRSSESSPRSRSRSSRSRSYSR--SYTRSRSLASSHSR-----SRSPSSRSHSRNK 731
Query: 563 ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 622
S + S+ S+ + R+ +L + K S S +H S + +Y K
Sbjct: 732 YS-DHSQCSRSSSYTSISSDDGRRA---KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787
Query: 623 SAAMTLNERFTSYQKATEEHSTRQKSPEIHR-RIDISPSTLRKHTRLAGEERVFKEENQK 681
+R + +K +E S+ S + + + + S K + E K+E +
Sbjct: 788 G-----RDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR 842
Query: 682 GDKKLRCDSADLRHDIDRRRKERSKE--RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 739
G++K + + + H R KE + R SK R K Y K D
Sbjct: 843 GEEKSKSE-RECPHSKKRTLKENLSDHLRNGSKPKR---------------KNYAGSKWD 886
Query: 740 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 781
S+ E+D +++S + + PS S +EE E+ + E E H
Sbjct: 887 SESNSERDVTKNSKNDSHPS--SDKEEGEATSDSESEVSEIH 926
Score = 39.7 bits (91), Expect = 0.013
Identities = 91/426 (21%), Positives = 159/426 (37%), Gaps = 80/426 (18%)
Query: 388 ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKV--SLK 445
E ++K SEG D+ S + + S + H + K + KV S K
Sbjct: 186 EKKRKKPTHSEGSDSSSN--------SSSSSESSSESELEHERSRRRKHKRRPKVKRSKK 237
Query: 446 GNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKL 505
+E+ E +N ER T + + + E+ V+ PE++
Sbjct: 238 RRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVR-----PEEI----- 287
Query: 506 KDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK-MAPVPLDDSNRPAS 564
PP+ +N + R + P+ + PE K+ +AP+ S++ S
Sbjct: 288 -------PPVPEN-----RFLLRRDMPVV-------TAEPEPKIPDVAPIV---SDQKPS 325
Query: 565 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE--QYFK 622
++K S +K + +I H P S+S SES H KE Q +
Sbjct: 326 VSK----------SGRKIKGRGTIRYHT--PPRSRSCSESDDDDSSETPPHWKEEMQRLR 373
Query: 623 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI----------DISPSTLRKHTRLAGEE 672
+ E+++ K ++ S+R + +R D+S + H + +E
Sbjct: 374 AYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433
Query: 673 RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS--RKQEKTPKDY 730
+ K + +KG K+ C RR K+ K R ESS S R+ + +
Sbjct: 434 KKVKHK-KKGKKQKHC----------RRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRE 482
Query: 731 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFA 790
+ +S S H ++D S+S S + SSR+ SK + + + S +
Sbjct: 483 RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS 542
Query: 791 GVSRPR 796
SR R
Sbjct: 543 SHSRSR 548
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 78.6 bits (192), Expect = 3e-14
Identities = 127/660 (19%), Positives = 213/660 (32%), Gaps = 15/660 (2%)
Query: 112 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171
S S S SS S S S SS S S SS SS S S S + K++
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
E S S+ + D+ D S++ D + S++++ + D+S S S S
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS-----DSSDSSDSSDSSSSS 681
Query: 232 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291
++ S SS SD+ S + ++ S S + S S + SS S S NS
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS- 740
Query: 292 IHHIPSRRSPAKTIAPQNAPRDES-RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLL 350
S S + + + D S SS D D + D +
Sbjct: 741 -----SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Query: 351 DRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ 410
D N+ D S + ++ + + SD + S+ D+ + D
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 411 FRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVER 470
+S ++ S ++ N+ + S S + SD + +
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 471 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL-HKNLDAREKSTFRE 529
S+ E +S+ + S + S + D S N S +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 589
S +SDS + + +S + D +S +S S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS-S 1034
Query: 590 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 649
D +S S+ S + ++ + + +S + + S S
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 650 EIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERG 709
+ D S S+ + + + + D DS+D + D S +
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 710 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 769
DS S +SS S D + + D S D S SS SS S S S + +S
Sbjct: 1155 DSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Score = 78.2 bits (191), Expect = 3e-14
Identities = 157/785 (20%), Positives = 262/785 (33%), Gaps = 71/785 (9%)
Query: 2 GRSNSR----SHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDY 57
G+S+S S SS S S SS S S+S SS S S S S S D S D
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604
Query: 58 RRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR 117
++ + S + S+S S
Sbjct: 605 SDSSDSSDSS------------------------------DSSDSSDSKSDSSKSESDSS 634
Query: 118 RSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEE 176
S S S S S S S +S S SS+S +SS S S S S + ++ +
Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKSSA-----TSGDIWPGLSAYDNSPRSPHSPSP 231
S S+S + D+ + D S+S D N +S+ S D ++ D+S S S S
Sbjct: 695 SSNSSESSDS-SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 232 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291
++ S SS+ SD+ S+ ++ S S + S + S S S + SS S S NS
Sbjct: 754 DSSDSSDSSNSSDSS-----DSSDSSDSSDSSNSSDSNDSSNS-SDSSDSSNSSDSSNSS 807
Query: 292 IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD 351
S S + + ++ SS D D + G +D +R D
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS----DSDSSNR---SD 860
Query: 352 RGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQF 411
N+ D S + + ++ ++ S+ N S+ D ++ +
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNES-----SNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 412 RKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERP 471
S +D +S ++ + N+ + S S + SD + ++
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 472 STTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES 531
S+ + +S+ + S S D D S + D+ S S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS----NSSDSSNSSDSSNSS 1031
Query: 532 PLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDH 591
+SDS + + +S + D +S S + S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS---- 1087
Query: 592 IKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEI 651
+S S+ S ++ + N +S + + S S +
Sbjct: 1088 ---SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 652 HRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS 711
+ S S+ + + + + + D DS+D D S + DS
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 712 KGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 771
S +SS S D + D ++ D S SS SS S S S + +S
Sbjct: 1205 SDSSDSSDS-SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Query: 772 EREEE 776
+ +E
Sbjct: 1264 DSNDE 1268
Score = 75.5 bits (184), Expect = 2e-13
Identities = 150/782 (19%), Positives = 245/782 (31%), Gaps = 60/782 (7%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS----SRSRSRTYSRSRSRDRMYSRDYRRD 60
N +S S + KS S S S S + S S S S S + S S D S D
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
+N + + S+S + S S
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
S + S S S SS S SSSS SS S S S + + + ++ + S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
S D+ + S+S D N S S D ++ D+S S S S ++ S SS
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
SD+ S + + N+ S S S S + S S + S S S NS S S
Sbjct: 775 DSSDSSNSSDSNDSSNS-SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 301 PAKTIAPQNAPRDESRG------------RSSFYPDGGDQETAKTGKFLKRFTDEESRVF 348
+ + + D S G SS D D + + +
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 349 LLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDY 408
D N+ D ++S S D SD + N S+ D+ ++ +
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 409 RQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVV 468
S + + ++ ++ + S S + SD + ++
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 469 ERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFR 528
+ +++ + + NS + S + S D D S + + D+ + S
Sbjct: 1014 DSSNSSDSSNSSDSSNSS-----DSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDSS 1067
Query: 529 EESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSI 588
+ S +SDS D S+ S S+ +
Sbjct: 1068 DSSDSSDSSDSSDSSESS----------DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 589 FDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKS 648
D +S S+ S +++ + + +S + + S S
Sbjct: 1118 SDSSNSSDSSDSSDSS------------DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 649 PEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER 708
+ D S S+ + + + + + D DS+D D S +
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225
Query: 709 GDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 768
DS S ESS S D S D S SS SS S S + + +
Sbjct: 1226 SDSSDSNESSDS-------------SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Query: 769 SK 770
SK
Sbjct: 1273 SK 1274
Score = 64.7 bits (156), Expect = 4e-10
Identities = 99/506 (19%), Positives = 163/506 (32%), Gaps = 25/506 (4%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S++ S SS S + S SS+ S S S S + S + + S S D S D +
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
+ G R S S S S S +S
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDS---------------SDSSNSSDSSDSSDSNESSNSS 892
Query: 124 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKS 183
S S S S S SS+S SS S S S + + ++ +S S S
Sbjct: 893 DSSDSSNSS--DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 184 QEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCS 243
+ D S S D + +S+ S D + D+S S S S ++ S SS S
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010
Query: 244 DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAK 303
D+ S + N+ + S S S + SS S S NS S S +
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 304 TIAPQNAPRDESR-------GRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTR 356
+ + D S SS D D + +D D ++
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 357 DKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVL 416
D S + + ++ E ++ D +S + D ++ + S
Sbjct: 1131 DSSDSSDSSNSSDSSDSS-ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 417 ADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKD 476
+D S ++ ++ + S S + SD + + ++ + ++
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249
Query: 477 KHKEEDKNSERITVKKETQSPEQVKS 502
+ +S T +S Q KS
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 63.2 bits (152), Expect = 1e-09
Identities = 125/651 (19%), Positives = 217/651 (33%), Gaps = 33/651 (5%)
Query: 135 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
+S S +SSSR + Y+ S SK G+ +K AE + + + + S +D
Sbjct: 478 NSESDNNSSSRGDASYN-SDESKDNGNGS-DSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 195 PSESIDEFN-KSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
++ D KS ++ D ++ D+S S S S SSS SD+ + S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS-----DSNSSSDSDSSDSDSSDS 590
Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313
+ + S S+S S S S + S S S +S S + ++ D
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS------KSESDSSDSDSKSDSSD 644
Query: 314 ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD----KEASKEKGSEKG 369
+ SS D D + +D D N+ D ++S S
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 370 RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHR 429
+ + ++ D + S N S+ D+ + D S ++ S ++
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS--SNSSDSSDSSDSS 762
Query: 430 NTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERIT 489
N+ + S S + SD + ++ + +++ + +S+
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 490 VKKETQSPEQVKSEKLKDLFDYS-------PPLHKNLDAREKSTFREESPLRIKMIASDS 542
+ S + S D D S D+ S + S +SDS
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 543 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK--EQEFRSIFDHIKLPQASKS 600
+ D SN S + D +S S E + D+ +S S
Sbjct: 883 SDSNESSNSSD-SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 601 --TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS 658
+S+S S + + S + N +S + + S S + D S
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 659 PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 718
S+ + + + + + D DS+D D S + DS S +SS
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 719 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 769
S D + D S+ D S SS SS S S S + +S
Sbjct: 1062 DS-SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Score = 55.8 bits (133), Expect = 2e-07
Identities = 88/398 (22%), Positives = 122/398 (30%), Gaps = 25/398 (6%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S+ S+SS S + S SS S S + S S S S S S S D S + +
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
+ N S + S S S
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 124 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKS 183
S S S SS S SS S SS S S S + ++ +S S S
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 184 QEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCS 243
+ + D S S D + S+ S D ++ D+S S S S ++ S SS S
Sbjct: 1109 SDSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 244 DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAK 303
D+ S + N+ S S S + SS S S +S S S +
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226
Query: 304 TIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKE 363
+ N D S D D + +D +T D +
Sbjct: 1227 DSSDSNESSDSS--------DSSDSSDSSNSSDSSDSSDSSD--------STSDSNDESD 1270
Query: 364 KGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDD 401
S+ G D SD +S N S DD
Sbjct: 1271 SQSKSGNGNNNGSD-------SDSDSEGSDSNHSTSDD 1301
Score = 30.4 bits (67), Expect = 7.9
Identities = 29/130 (22%), Positives = 43/130 (33%), Gaps = 29/130 (22%)
Query: 675 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD----------------SKGSRE-- 716
F +++ +GD D ++ D + S RGD SKG+ +
Sbjct: 455 FDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDD 514
Query: 717 -----------SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 765
S+G+ D + K DS D S SS SS S S SS
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 766 EKESKKEREE 775
S + +
Sbjct: 575 NSSSDSDSSD 584
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 77.4 bits (189), Expect = 6e-14
Identities = 168/841 (19%), Positives = 311/841 (36%), Gaps = 96/841 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
+ S+S S S S + S+SRS S + R SRS SR++SRS SR Y R R R
Sbjct: 649 KEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSR 708
Query: 63 NNRGMRRPYGY-RGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
N R R +GY R R R P + R HSRS R +SP +R+V
Sbjct: 709 NYRSRSRSHGYHRSRSRS---------------PPYRRYHSRSRSPQAFRGQSPNKRNVP 753
Query: 122 SQRSRSRSRRSYRSSRSPRSSSS-RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
+ YR P + S + P K R +E + K E +
Sbjct: 754 QGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKER-YREWERKYREWYEKYYKGYA 812
Query: 181 SKSQEEPKDTFEHDPSESIDEFN--KSSATSG--DIWPGLSAYDNSPRSPHSPSPIATPP 236
+ +Q P E+ E N S T G + + G ++ + + P ++
Sbjct: 813 AGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARD 872
Query: 237 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---------NGSSR---- 283
+ + +A + H +H R G S G + SR
Sbjct: 873 GHNQKDNTKSKEKESENAPGDGKGNKHK-KHRKRRKGEESEGFLNPELLETSRKSREPTG 931
Query: 284 YSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT-GKFLKRFTD 342
++ + +PS R A + + + +S D +++ K G KR D
Sbjct: 932 VEENKTDSLFVLPS-RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKND 990
Query: 343 -----EESRVFLLDRG------NTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE--- 388
++ + +G R++ E +K + E D S K+
Sbjct: 991 GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKI 1050
Query: 389 -SGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGN 447
+K + + +ET+ ++ + V D K + EE+ K K N
Sbjct: 1051 TGTPRKAHSKSAKEHQETKPVKE--EKVKKDYSKDVKSEKLTTKEEKAKKPNEK-----N 1103
Query: 448 RESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKL-- 505
+ D E++ K +E G + S++ K E + + K++ + P+ K ++
Sbjct: 1104 KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKME-PDTEKMDRTPE 1162
Query: 506 KDLFDYSPPLH---------KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPL 556
KD S P K + + E + +E +++ +S + +VK K+
Sbjct: 1163 KDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVT 1222
Query: 557 DDSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLPQASKSTSESFIQHIVSL 612
++L +ST V+K +E R++ IK + + + + + ++ +
Sbjct: 1223 GTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTMEEYNNDNTAPAEDVIIM 1279
Query: 613 VHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEE 672
+ + ++ K + E K+T+ S+ K + + + PS + K+ E
Sbjct: 1280 IQVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1335
Query: 673 RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG------SRESSGSRKQEKT 726
E+ QK K + + ++H++ + S E+G +K +E+ RK
Sbjct: 1336 ---SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQ 1390
Query: 727 PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEY 786
P+ + K S+ + +S S + K+ R++ KT ++ +EY
Sbjct: 1391 PEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDK--KTDYDTREY 1448
Query: 787 S 787
S
Sbjct: 1449 S 1449
Score = 76.3 bits (186), Expect = 1e-13
Identities = 147/749 (19%), Positives = 295/749 (39%), Gaps = 110/749 (14%)
Query: 103 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 149
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
Query: 150 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 203
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
Query: 204 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 248
+SS+ SP+ P + TP S S AP +
Sbjct: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1185
Query: 249 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 297
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1186 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1245
Query: 298 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 357
R+S KT D R + + TA + +S+ + D
Sbjct: 1246 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1291
Query: 358 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 417
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1292 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1348
Query: 418 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY-KLKETGYVVE 469
+ K+ A++ T++ K + + + S +E N +L E G
Sbjct: 1349 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
Query: 470 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 529
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1464
Query: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 589
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1465 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1515
Query: 590 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLNERFTSYQK----ATEE 641
D + + +KS ++ + H++ ++ KE LN T +K +
Sbjct: 1516 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1574
Query: 642 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDR 699
ST + P++ +S S L + T A E + E + + + ++ + S ++ D+
Sbjct: 1575 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1633
Query: 700 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 759
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1634 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1689
Query: 760 SPSSREEKESKKEREEEFKTHHEMKEYSG 788
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
Score = 75.1 bits (183), Expect = 3e-13
Identities = 189/886 (21%), Positives = 318/886 (35%), Gaps = 137/886 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDR--MYSRDYRR 59
GR SR++ SRS+S SRSRS + +RY SRSRS R +S ++ + + R
Sbjct: 703 GRGKSRNYRSRSRSHGYHRSRSRSPPY---RRYHSRSRSPQAFRGQSPNKRNVPQGETER 759
Query: 60 DYRNN-RGMRRPY---GYRGRG---RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS 112
+Y N R + PY Y GR R ++ R YR W ++ + G
Sbjct: 760 EYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYRE-WYEKYYKGYAAGAQPR 818
Query: 113 RSPKRRSVSSQR-----------SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS 161
S R + S +R +R R R Y +S RS + S+ P +S R G
Sbjct: 819 PSANRENFSPERFLPLNIRNSPFTRGR-REDYVGGQSHRSRNIGSNYP---EKLSARDGH 874
Query: 162 QEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
+K K++ + E +P K + K + K + G + P L
Sbjct: 875 NQKDNTKSKEKESENAPGDGKGNKHKKHR----------KRRKGEESEGFLNPELLETSR 924
Query: 222 SPRSP-----HSPSPIATPPSQ--SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
R P + + PS+ ++ D PM + + K+ + +
Sbjct: 925 KSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984
Query: 275 GSVGNGSSRYSPSQN------SPIHHI-------PSRRSPAKTIAPQNAPRDESRGRSSF 321
N S S +N P + P P K + D ++ SS
Sbjct: 985 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1044
Query: 322 YPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEK-----GRAEGEWE 376
D ++ T K + E + + K+ SK+ SEK +A+ E
Sbjct: 1045 QKD--EKITGTPRKAHSKSAKEHQETKPVKEEKVK-KDYSKDVKSEKLTTKEEKAKKPNE 1101
Query: 377 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEE-EG 435
+ LD +K K+K + D E+ + + V S +TE+ +
Sbjct: 1102 KNKPLDNKGEKR--KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDR 1159
Query: 436 LKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI---TVKK 492
K K+SL + E K+ T E S TK+ ++ + S ++ VK
Sbjct: 1160 TPEKDKISLSAPAKKIKLNRETGKKIGST----ENISNTKEPSEKLESTSSKVKQEKVKG 1215
Query: 493 ETQSPEQVKSEKLKDLFDYS-------PPLHKNLDA---------------REKSTFREE 530
+ + L DY+ P+ K+ + + + E+
Sbjct: 1216 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1275
Query: 531 SPLRIKMIAS----DSHRPEVKLKMAPVPLDDSNRPASLTKD-RLLASTLVHSVKKEQEF 585
+ I++ S D E + + P+ +PAS+ K+ S +V +KE E
Sbjct: 1276 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESE- 1334
Query: 586 RSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 645
K+ + +K S IQH V K T + ++ +K E
Sbjct: 1335 ----PSEKIQKFTKDVSHEIIQHEVK---SSKNSASSEKGKTKDRDYSVLEKENPEKRKN 1387
Query: 646 QKSPEIHRRID----------ISPS-----TLRKH--TRLAGEERVFKEENQKGDKKLRC 688
PE +D +S S T KH TR + + ++K D R
Sbjct: 1388 STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTRE 1447
Query: 689 DSADLRHD--IDRRRKERSKERGDSKGSRESSGSRKQEKTPK----DYKEYKSYKDDSKH 742
S+ R D + R++ S R S + + R++ PK D K KS S+
Sbjct: 1448 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSK--KSNSSPSRD 1505
Query: 743 KREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 788
++ DH +++ + P+ + +K K+RE+ KE SG
Sbjct: 1506 RKPHDH-KATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG 1550
Score = 68.2 bits (165), Expect = 3e-11
Identities = 207/992 (20%), Positives = 353/992 (35%), Gaps = 173/992 (17%)
Query: 15 SRSQSSSRSRSRSHSRKKRYSSRSRSR---TYSRSRS---RDRMYSRDYRRDYRNNRGMR 68
SR + R K YS S SR TYS+SRS R R YSR + R + +
Sbjct: 637 SREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRS 696
Query: 69 RPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS--QRSR 126
PY PRRGR +SR+ + RS S RSR
Sbjct: 697 PPY---------------------------------PRRGRGKSRNYRSRSRSHGYHRSR 723
Query: 127 SRS---RRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKS 183
SRS RR + SRSP+ + R SP +K V + +E + E P +
Sbjct: 724 SRSPPYRRYHSRSRSPQ--AFRGQSP-NKRNVPQGETEREYFNRYREVPPPYDMKAYYGR 780
Query: 184 QEEPKDTFEHDP--------SESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP 235
+ +D FE + E +++ K A P + + SP P I
Sbjct: 781 SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPER-FLPLNIRNS 839
Query: 236 PSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 295
P D + H ++N S + + R G N S+ S+N+P
Sbjct: 840 PFTRGRREDY-VGGQSHRSRNIGSNYPEKLS---ARDGHNQKDNTKSKEKESENAP---- 891
Query: 296 PSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNT 355
GD + K K KR EES FL
Sbjct: 892 ------------------------------GDGKGNKHKKHRKRRKGEESEGFLNPELLE 921
Query: 356 RDKEASKEKGSEKGRAEG---------------EWEDQEALDYFSDKESGKQKFN--DSE 398
+++ + G E+ + + E D E++ + S E K++ + ++
Sbjct: 922 TSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK 981
Query: 399 GDDTEETED------YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDG 452
GD T+ D K Q K E +K + + K +
Sbjct: 982 GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSS 1041
Query: 453 FREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVK---KETQSPE-QVKSEKLKDL 508
+K+ K+ TG + S + +H+E E K K+ +S + K EK K
Sbjct: 1042 SSSQKDEKI--TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKP 1099
Query: 509 FDYSPPLHKNLDAREKSTFR-------EESPLRI-KMIASDSHRPEVKLKMAPVPLDDSN 560
+ + PL + R++ T E S ++I K+ ++ +P K KM P D
Sbjct: 1100 NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEP---DTEK 1156
Query: 561 RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQY 620
+ KD++ S +K +E + +K SE + S VK++
Sbjct: 1157 MDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK----LESTSSKVKQEK 1212
Query: 621 FK------------SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRL 668
K S++ ++ TS + + +K+ I +T
Sbjct: 1213 VKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAP 1272
Query: 669 AGEERVFKEENQ-KGDK-KLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT 726
A + + + Q K DK + D++ + + ++ S+ + EK
Sbjct: 1273 AEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE 1332
Query: 727 PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES--KKEREEEFKTHHEMK 784
+ ++ + + D H+ Q +SS +SAS +++ S +KE E+ K + +
Sbjct: 1333 SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPE 1392
Query: 785 EYSGFAGVSRPRGTFFRI-RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDP-EYTPK 842
+ S ++ +G F + + AR +T +++ R K+ ++D EY+
Sbjct: 1393 KESNLDRLNE-QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSS 1451
Query: 843 SKKYFLHD----------DRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP---KWTH 889
++ ++ ++D K R ++G G + KKS SSP + H
Sbjct: 1452 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG--DSKKSNSSPSRDRKPH 1509
Query: 890 D-KYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
D K D +EE + KDR K E
Sbjct: 1510 DHKATYDTKRPNEETKSVDKNPCKDREKHVLE 1541
Score = 57.8 bits (138), Expect = 5e-08
Identities = 151/727 (20%), Positives = 257/727 (35%), Gaps = 129/727 (17%)
Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRS--------PRSSSSRS 146
P+ R RR + S+SP S S SRS +Y SRS RS S
Sbjct: 635 PLSREEFYREQRRLKEESKSPYSGS-----SYSRSSYTYSKSRSGSTRSRSYSRSFSRSH 689
Query: 147 SSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 206
S YS+SP RRG + + ++ + +S+S+ P + H S S F S
Sbjct: 690 SRSYSRSPPYPRRGRGKSRNYRSRS--RSHGYHRSRSRSPPYRRY-HSRSRSPQAFRGQS 746
Query: 207 ATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ 266
++ G + + R P P S K + +
Sbjct: 747 PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFE-----KERYREWERKYR 801
Query: 267 HSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 326
E+ G R PS N + P R P +N+P +RGR Y G
Sbjct: 802 EWYEKYYKGYAAGAQPR--PSANRE-NFSPERFLPLNI---RNSP--FTRGRREDYVGGQ 853
Query: 327 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSD 386
+ G ++ ++ D N +D SKEK SE +G+ +
Sbjct: 854 SHRSRNIG------SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK------- 900
Query: 387 KESGKQKFNDSEGD-DTEETEDYRQFRKSVLADQGKS---FATASHRNT--------EEE 434
K ++K +SEG + E E R+ R+ ++ K+ F S + + E
Sbjct: 901 KHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE 960
Query: 435 GLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKET 494
+ +KS VS K RE D +P DK K ++ S ++ K+
Sbjct: 961 SITFKS-VSEKDKRERD------------------KPKAKGDKTKRKNDGS-AVSKKENI 1000
Query: 495 QSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPV 554
P + EK +D + + R E P++ K K
Sbjct: 1001 VKPAKGPQEK--------------VDGERERSPRSEPPIK-------------KAKEETP 1033
Query: 555 PLDDSNRPASLTKDRLLAST--LVH--SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIV 610
D++ +S KD + T H S K+ QE + P + + + + +
Sbjct: 1034 KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETK--------PVKEEKVKKDYSKDVK 1085
Query: 611 SLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK----HT 666
S KE+ K NE+ E+ + + + + + S + K
Sbjct: 1086 SEKLTTKEEKAKKP----NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141
Query: 667 RLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ--E 724
+R + + +K D+ D L ++ + ++E G GS E+ + K+ E
Sbjct: 1142 VKPSPKRKMEPDTEKMDRTPEKDKISL--SAPAKKIKLNRETGKKIGSTENISNTKEPSE 1199
Query: 725 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSS----ASPSSPSSREEKESKKEREEEFKTH 780
K + K K K +R+ + SSS+ S SS ++S+++ + +
Sbjct: 1200 KLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVI 1259
Query: 781 HEMKEYS 787
M+EY+
Sbjct: 1260 KTMEEYN 1266
Score = 47.0 bits (110), Expect = 8e-05
Identities = 82/434 (18%), Positives = 168/434 (38%), Gaps = 60/434 (13%)
Query: 96 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 142
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
Query: 143 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 202
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1469
Query: 203 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 257
NK SA S N PR T S+ S+ S + H K T
Sbjct: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
Query: 258 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 317
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
Query: 318 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 374
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
Query: 375 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 428
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
Query: 429 RNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI 488
++ K K K K +++ ++ K K G VE + K KHK++ +
Sbjct: 1686 SAESQDSKKKKKKKEKKKHKKHKKHKKHK----KHAGTEVELEKSQKHKHKKKKSKKNKD 1741
Query: 489 TVKKETQSPEQVKS 502
K++ + ++VKS
Sbjct: 1742 KEKEKEKDDQKVKS 1755
Score = 45.8 bits (107), Expect = 2e-04
Identities = 66/300 (22%), Positives = 114/300 (38%), Gaps = 27/300 (9%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSR-----SRTYSRSRSRDRMYSRDY 57
+ N +S S SK S +R+ S K +R + +R YS S+ RD
Sbjct: 1403 QGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTR 1462
Query: 58 RRD--YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP 115
R+D RN R + G G + P +R+ ++ +
Sbjct: 1463 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1522
Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSR----SSSPYSKSPVSKRRGSQEKQTKKAEG 171
+ +SV + R + + + SS ++ + P ++ + G +K T K +
Sbjct: 1523 ETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKP 1582
Query: 172 EPQEESPLKSK-SQEEPKDTFEHDPSESIDEFN---KSSATSGDIWPGL--SAYDNSPRS 225
+ S L S ++E + FE D +ES E N K +SG+I L + + S
Sbjct: 1583 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1642
Query: 226 PHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 285
+ + + S++ S HS+ + SHS S RS S S + S+ S
Sbjct: 1643 LDTAAVVQVGISRNQS----------HSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1692
Score = 40.0 bits (92), Expect = 0.010
Identities = 114/639 (17%), Positives = 224/639 (35%), Gaps = 83/639 (12%)
Query: 134 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 193
+ R+P S+P K +++ G + T+ + L+S S + ++ +
Sbjct: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
Query: 194 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
+ SS+T D + S SP+ ++ + ++
Sbjct: 1216 KVRRKVTGTEGSSST---------LVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA--PQNAP 311
NT I +S S PI + S K ++ P N
Sbjct: 1267 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIV 1326
Query: 312 RDESRGRSSFYPDGGDQETAKTGKFLKRFTDE--------ESRVFLLDRGNTRDKEAS-- 361
+ YP+ + + K KF K + E ++G T+D++ S
Sbjct: 1327 K---------YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVL 1377
Query: 362 KEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGK 421
+++ EK + + E + LD +++ + K S+ T + D S A K
Sbjct: 1378 EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD------STRASSNK 1431
Query: 422 SFATASHRNTEEEGLKYKS-------------KVSLKGNRESDGF-----REEKNYKLKE 463
F + T+ + +Y S K S N++S REE++ K
Sbjct: 1432 DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
Query: 464 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE 523
TG + S+ K D + T K+ + + V KD + L+AR
Sbjct: 1492 TGDSKKSNSSPSRDRKPHDHKATYDT-KRPNEETKSVDKNPCKDREKHV------LEARN 1544
Query: 524 KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQ 583
+E S ++ I + PE +++ + ++ K +L S+ + S +
Sbjct: 1545 N---KESSGNKLLYILNP---PETQVEKEQIT-GQIDKSTVKPKPQLSHSSRLSSDLTRE 1597
Query: 584 EFRSIFDHIKLPQASKSTSESFI-----QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA 638
+ F+ P ++S SES + + ++ +K++ + A +L+
Sbjct: 1598 TDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1653
Query: 639 TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE------ERVFKEENQKGDKKLRCDSAD 692
+ S S R S S R H+ A ++ K++ +K KK +
Sbjct: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1713
Query: 693 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 731
+H E+S++ K + + +++EK D K
Sbjct: 1714 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
Score = 34.7 bits (78), Expect = 0.42
Identities = 77/417 (18%), Positives = 133/417 (31%), Gaps = 47/417 (11%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 66
+ + + K+ +Q S + + + S S+S +R+ + +D+ NR
Sbjct: 1379 KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD 1438
Query: 67 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 126
+ Y R RR ++ R S S + S S Q+++
Sbjct: 1439 KKTDYDTREYSSS------------------KRRDEKNELTRRKDSPSRNKDSASGQKNK 1480
Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
R R + S S SS + P + K+ P EE+ KS +
Sbjct: 1481 PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR-------PNEET--KSVDKNP 1531
Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
KD +H + E + +SG+ Y +P T S+ P
Sbjct: 1532 CKDREKH-----VLEARNNKESSGN----KLLYILNPPETQVEKEQITGQIDKSTVKPKP 1582
Query: 247 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN-------GSSRYSPSQNSPIHHIPSRR 299
LS + ++ + P+ + S S N S S I
Sbjct: 1583 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1642
Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD-RGNTRDK 358
+ R++S S P + + +G + + S D + + K
Sbjct: 1643 LDTAAVVQVGISRNQSHSSPSVSPS---RSHSPSGSQTRSHSSSASSAESQDSKKKKKKK 1699
Query: 359 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 415
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1700 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
+G S ++SHSS S SRS S S S++RSHS + S+ + + + +
Sbjct: 1651 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1710
Query: 59 RDYRNNRG 66
+ ++ + G
Sbjct: 1711 KKHKKHAG 1718
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/205 (31%), Positives = 94/205 (45%), Gaps = 24/205 (11%)
Query: 12 RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71
RS+SR + SRSRSR +R R R + R R RDR Y ++ + R R
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRER 388
Query: 72 GYRGRGRG------YYQGGGGRYHRGGYRPVWN-RRHSRS-----PRRGRSRSRSPKRRS 119
R RG + + R HR R ++HSRS R RSRSR+ +RS
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
RSRS+ + S + S S+ R S+S R S EK K+ +E+S
Sbjct: 449 ----RSRSKEKSSKHKNESKEKSNKR-----SRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204
+S+S+E + + D S+S D+ +K
Sbjct: 500 RSRSKER---SHKRDHSDSKDQSDK 521
Score = 58.5 bits (140), Expect = 3e-08
Identities = 67/311 (21%), Positives = 131/311 (42%), Gaps = 27/311 (8%)
Query: 615 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 674
HV+ + +S +L+ R + + + H HR S S R+ R +R+
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSH---------HREGHGSSSFDRELEREKERQRL 304
Query: 675 FKEENQKGDKKLRCDSADLRHDIDRRR-----KERSKERG-DSKGSRESSGSRKQEKTPK 728
+E ++ ++ R S D ++RRR + RS+ R D KG R ++++ +
Sbjct: 305 EREAKEREKERRRSRSID--RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362
Query: 729 DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 788
+ + Y + ++RE++ RS S S EEK+ K+++++ + + ++
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-RHRDDKRDSKK 421
Query: 789 FAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFL 848
SR R + R R R+R N G + + + +K K + E + K +
Sbjct: 422 EKKHSRSRSRERKHRSRSRSR------NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG- 474
Query: 849 HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETME-N 907
R D V+ KR ++ R R K+ + K Q D +++E
Sbjct: 475 SQGRTDSVEKSKKREHSPSK-EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE 533
Query: 908 NEEKKDRRKEE 918
++EK+ + K+E
Sbjct: 534 SQEKQHKNKDE 544
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 14/182 (7%)
Query: 2 GRSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
GR R + R R + RSR RS ++ R + + R R RD +++
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRY--------HRGGYRPVWNRRHSRSPRRGRSRS 112
+++R R +R R R G R H+ + N+R SRS +GR+ S
Sbjct: 423 KKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR-SRSGSQGRTDS 481
Query: 113 --RSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-KSPVSKRRGSQEKQTKK 168
+S KR S S ++SR RSR RS + S S S + + S + SQEKQ K
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541
Query: 169 AE 170
+
Sbjct: 542 KD 543
Score = 53.9 bits (128), Expect = 7e-07
Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 22/254 (8%)
Query: 294 HIPSRRS--PAKTIAPQNAPRD--------ESRGRSSFYPD-GGDQETAKTGKFLKRFTD 342
H+ RRS P ++++P+ +PR E G SSF + ++E + + K
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313
Query: 343 EESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDT 402
E R +DRG R + S+E+ + R+ D+ D +KE+ + + D + D
Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKE 373
Query: 403 EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLK 462
E ++ +S + +S S EE+ K K R D R+ K K
Sbjct: 374 RGNEREKERERS----RERSKEQRSRGEVEEK----KHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 463 ETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR 522
ER ++ + + K S + +K ++ + K + K S D+
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS---QGRTDSV 482
Query: 523 EKSTFREESPLRIK 536
EKS RE SP + K
Sbjct: 483 EKSKKREHSPSKEK 496
Score = 43.5 bits (101), Expect = 0.001
Identities = 55/267 (20%), Positives = 110/267 (41%), Gaps = 21/267 (7%)
Query: 251 VHSAKNTPSQHSHSIQHSPERSGSGS---VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
V ++ + S S + SP RS S S G+GSS + R +
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314
Query: 308 QNAPRDESRG----RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKE 363
+ R RG RS + ++ K +R D E R +RG RD++ KE
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE-REKENERGRRRDRDYDKE 373
Query: 364 KGSEKG----RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQF-------R 412
+G+E+ R+ ++Q + +K+ + K + DD +++ ++ R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Query: 413 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 472
K + ++ S ++E+ K+K++ K N+ S + + ++++ PS
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 473 TTKDKHKEEDKNSERITVKKETQSPEQ 499
K+K ++ ++ ER + + S +Q
Sbjct: 494 --KEKSRKRSRSKERSHKRDHSDSKDQ 518
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/146 (21%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 640 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGD----KKLRCDSADLRH 695
E+ K HR +KH+R ER + ++ + + R +H
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Query: 696 DIDRRRKERSKERGDSKGSRES-SGSRKQEKTPKDYKEYK-SYKDDSKHKREQDHSRSSS 753
+ + K + R S+G +S S+K+E +P K K S + HKR+ S+ S
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519
Query: 754 SSASPSSPSSREEKESKKEREEEFKT 779
S E++ +K+ + + +T
Sbjct: 520 DKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 31/229 (13%)
Query: 693 LRHDIDRRRKERSKE-RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 751
++ +ID++ K R ++ + D K E + + + + S + + R + H R
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284
Query: 752 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGV 811
S+S RE++ + ERE + + + S G+ R R R R R R+R
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRS---RSRERHRSRS- 340
Query: 812 FAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHD-DRDDGVDYWAKRGRGRGTFQ 870
+ + +R ++ E + E ++ +D +R + + +R R R Q
Sbjct: 341 --------RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQ 392
Query: 871 RGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEK 919
R RG KK +++++ + ++K+D +KE+K
Sbjct: 393 RSRGEVEEKKH-----------------KEDKDDRRHRDDKRDSKKEKK 424
Score = 42.7 bits (99), Expect = 0.002
Identities = 65/291 (22%), Positives = 106/291 (36%), Gaps = 22/291 (7%)
Query: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSS----RSPRSSSSRSSSPYSKSP 154
RR SRSPRR S RSP+R RSRS R + SS R + +K
Sbjct: 257 RRRSRSPRRSLSPRRSPRR-----SRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311
Query: 155 VSKRRGSQ--EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDI 212
+RR S+ ++ ++ +E +S+S++ D + D E E + D
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRD-REREKENERGRRRDRD- 369
Query: 213 WPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS-PER 271
YD + + S + H +H + S E+
Sbjct: 370 ------YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEK 423
Query: 272 SGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETA 331
S S S S++ RS K+ +N +++S RS G
Sbjct: 424 KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 332 KTGKFLKRFTDEES--RVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEA 380
K+ K + E+S R +R + RD SK++ + R + +QE+
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQES 534
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 76.3 bits (186), Expect = 1e-13
Identities = 69/214 (32%), Positives = 96/214 (44%), Gaps = 19/214 (8%)
Query: 3 RSNSRSHSSR-SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
R+ SRS +K + +SR+R RS SR + S R RSRT+ R RSR + Y R ++Y
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDR--SRRVRSRTHDRDRSRSKEYHRYREQEY 598
Query: 62 RNNRGMRRPYGYR---GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR 118
R RG R R GR R + R R R R+ R S+S K
Sbjct: 599 R-RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 119 SVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS------QEKQTKKAEGE 172
S S +R S+SR S+ S + R SP+SK S + + K+ +K
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717
Query: 173 PQEESPLKSKSQE-----EPKDTFEHDPSESIDE 201
++E+ KSK QE E F+H+ S DE
Sbjct: 718 VEKENQ-KSKGQENDHVHEKNKKFDHESSPGTDE 750
Score = 68.2 bits (165), Expect = 3e-11
Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 34/214 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRS----RSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
RS R H + + QS S+ RSRS + K+ S+S +S+S+ +DR R
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 59 -------------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 105
R +R R R R + YHR YR RR RS
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR--YREQEYRRRGRSR 605
Query: 106 RR------GRSRSRSPKRR---SVSSQR--SRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
R GRSRS+ +RR S SS+R S+SR++ YR+ S +SS + +S K
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES-KSSHRKENSESEKRM 664
Query: 155 VSKRR---GSQEKQTKKAEGEPQEESPLKSKSQE 185
SK R S + KKA+ + S +K SQ+
Sbjct: 665 YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698
Score = 65.5 bits (158), Expect = 2e-10
Identities = 134/667 (20%), Positives = 249/667 (37%), Gaps = 109/667 (16%)
Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
PK + ++ R +S S SS S SSS S S S S + E+++KK + + +
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS---SSDSSDSESATEEKSKKRKKKHR 235
Query: 175 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 234
+ S K +++ K + + SES E N + + P + P P + +
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAE-NLEAQPQSTVRP-----EEIPPIPENRFLMRK 289
Query: 235 PPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS--PERSGSGSVGNGSSRYSPSQNSPI 292
P ++ N P+ S Q RSG G G RY
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRY-------- 341
Query: 293 HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDR 352
R+P+++ R R R S P QE + + RV +R
Sbjct: 342 ------RTPSRS-------RSRDRFRRSETPPHWRQEMQRA---------QRMRVSSGER 379
Query: 353 GNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFR 412
DK E E R+ ++++ D+ + ES +K N+ E
Sbjct: 380 WIKGDKSELNEI-KENQRSPVRVKERKITDHRNVSESPNRK-NEKE-------------- 423
Query: 413 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 472
K V + S RN+E++ KYK+KV + +S +EK S
Sbjct: 424 KKVKDHKSNSKERDIRRNSEKDD-KYKNKVKKRAKSKSRSKSKEK--------------S 468
Query: 473 TTKDKHKEEDKNSE-RITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES 531
+K++ + ++N E R+ + + + E VK ++ K D++ K R S
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE------------KQSDSKGKDQERSRS 516
Query: 532 PLRIKMIASDSHRPE-VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 590
+ K + S S+ + K K +R +TK + ++ + ++ RS
Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD-RSRRV 575
Query: 591 HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPE 650
+ +S S+ + H +EQ ++ R S + R +S +
Sbjct: 576 RSRTHDRDRSRSKEY--------HRYREQEYR-------RRGRSRSRERRTPPGRSRSKD 620
Query: 651 IHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD 710
RR S S+ R+ ++ +++ +E++ +K +S ++R +S++
Sbjct: 621 RRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES-------EKRMYSKSRDHNS 673
Query: 711 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 770
S SRE R Q K + + + S + ++ + SS + S +E +
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHV 733
Query: 771 KEREEEF 777
E+ ++F
Sbjct: 734 HEKNKKF 740
Score = 65.1 bits (157), Expect = 3e-10
Identities = 125/635 (19%), Positives = 234/635 (36%), Gaps = 69/635 (10%)
Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222
E Q A +P E + S + PK + + + + SS++S D S+ D+
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSD---SDSSSDSQ 211
Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282
S S S AT S H + + S S E S
Sbjct: 212 SSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKK-SASSESEAENLEAQPQS 270
Query: 283 RYSPSQNSPI--HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 340
P + PI + R+SP K + R+ R R P+ ++ + +R
Sbjct: 271 TVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPN------SQPASYQRRL 324
Query: 341 TDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGD 400
S + RG R + S+ + ++ R E ++ + Q+ S G+
Sbjct: 325 LVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS------ETPPHWRQEMQRAQRMRVSSGE 378
Query: 401 -----DTEETEDYRQFRKSVLADQGKSFATASHRNTEEE-GLKYKSKVSLKGNRESDGFR 454
D E + ++ ++S + + K HRN E K + + +K ++ + R
Sbjct: 379 RWIKGDKSELNEIKENQRSPV--RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKER 436
Query: 455 EEKNYKLKETGY---VVERP-STTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFD 510
+ + K+ Y V +R S ++ K KE+ K+ ER + + K +D +
Sbjct: 437 DIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRD-HE 495
Query: 511 YSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE-VKLKMAPVPLDDSNRPASLTKDR 569
K D++ K R S + K + S S+ + K K +R +TK +
Sbjct: 496 NVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGK 555
Query: 570 LLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLN 629
++ + ++ RS + +S S+ + H +EQ ++
Sbjct: 556 HSYNSRTRERSRSRD-RSRRVRSRTHDRDRSRSKEY--------HRYREQEYR------- 599
Query: 630 ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD 689
R S + R +S + RR S S+ R+ ++ +++ +E++ +K +
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 690 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS 749
S ++R +S++ S SRE +K +D + K S QD+
Sbjct: 660 S-------EKRMYSKSRDHNSSNNSRE-------KKADRDQSPFSKIKQSS-----QDNE 700
Query: 750 RSSSSSASPSSPSSRE--EKESKKEREEEFKTHHE 782
SS + R EKE++K + +E HE
Sbjct: 701 LKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHE 735
Score = 57.8 bits (138), Expect = 5e-08
Identities = 125/604 (20%), Positives = 212/604 (35%), Gaps = 89/604 (14%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS---RSRSRDRMYSRDYRR 59
R NSR H K R +S + S S + +S R +R M +
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA 294
Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
D + + R R R Y R R + R + RG R R+P
Sbjct: 295 DEKERKNRERE---RERECNPPNSQPASYQR---RLLVTRSGRKIKGRGPRRYRTP---- 344
Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
SRSRSR +R S +P S R + +++ E + + SP+
Sbjct: 345 -----SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
+ K E K T + SES + N+ D H + ++
Sbjct: 400 RVK---ERKITDHRNVSESPNRKNEKEKKVKD---------------HKSNSKERDIRRN 441
Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 299
S D AK+ S S ER S+++ ++ + R
Sbjct: 442 SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER---------DSKHNRNEEKRM------R 486
Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 359
S +K +N E + S G DQE +++ +E L + N D
Sbjct: 487 SRSKGRDHENVKEKEKQSDSK----GKDQERSRS---------KEKSKQLESKSNEHDHS 533
Query: 360 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 419
SKEK RA+ + D GK +N + + + R+ R S D+
Sbjct: 534 KSKEKDR---RAQSRSRE-------CDITKGKHSYNSRTRERSRSRDRSRRVR-SRTHDR 582
Query: 420 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHK 479
+S + HR E+E + + + + R G K+ + + R S + ++ +
Sbjct: 583 DRSRSKEYHRYREQE-YRRRGRSRSRERRTPPGRSRSKDRRRR------RRDSRSSEREE 635
Query: 480 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL-RIKMI 538
+ +N ++ ++ S + SE K ++ S + + ++REK R++SP +IK
Sbjct: 636 SQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQS 695
Query: 539 ASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQAS 598
+ D+ LK S+ K + + VH K+ FDH P
Sbjct: 696 SQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK------FDHESSPGTD 749
Query: 599 KSTS 602
+ S
Sbjct: 750 EDKS 753
Score = 54.3 bits (129), Expect = 5e-07
Identities = 109/516 (21%), Positives = 207/516 (40%), Gaps = 68/516 (13%)
Query: 432 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVK 491
+EE ++KS S + SD + ++ + S T++K K+ K + + K
Sbjct: 185 KEEKKRHKSSSS-SSSSSSDSDSSSDSQSSSDSS---DSESATEEKSKKRKKKHRKNSRK 240
Query: 492 KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES--PL---RIKMIASDSHRPE 546
+ + ++ KS+K S +NL+A+ +ST R E P+ R M S E
Sbjct: 241 HKKEKKKRKKSKKSAS----SESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 547 VKLKMAPVPLD-----DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKST 601
+ K + +++PAS + RLL + +K R + P S+S
Sbjct: 297 KERKNRERERERECNPPNSQPASYQR-RLLVTRSGRKIKGRGPRR-----YRTP--SRSR 348
Query: 602 SESFIQHIVSLVHHVKE-QYFKSAAMTLNERFTSYQKAT-EEHSTRQKSPEIHRRIDISP 659
S + + H +E Q + ++ ER+ K+ E Q+SP + +
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSP-----VRVKE 403
Query: 660 STLRKHTRLA-GEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 718
+ H ++ R ++E + D K D+R + ++ K ++K + K ++ S
Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK---KRAKSKS 460
Query: 719 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES-----KKER 773
S+ +EK+ KS + DSKH R ++ S S +EK+S +ER
Sbjct: 461 RSKSKEKS-------KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQER 513
Query: 774 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKE- 832
+ +++ S S+ + R + R R + G ++ NS T + R ++
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHS--YNSRTRERSRSRDR 571
Query: 833 -----EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQR---GRGRFNFKKSGSS 884
+SK+Y + +++ + +RGR R +R GR R ++
Sbjct: 572 SRRVRSRTHDRDRSRSKEYHRYREQE-----YRRRGRSRSRERRTPPGRSRSKDRRRRRR 626
Query: 885 PKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 920
+ ++ + +D+ N E K RKE E
Sbjct: 627 DSRSSEREESQSRNKDK---YRNQESKSSHRKENSE 659
Score = 49.3 bits (116), Expect = 2e-05
Identities = 57/270 (21%), Positives = 106/270 (39%), Gaps = 37/270 (13%)
Query: 668 LAGEERVFKEENQKGD---------KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 718
++G+E V + ENQK D + L C + + + K+R K S S S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204
Query: 719 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK 778
S ++ D + +S ++ KR++ H + +SR+ K+ KK+R++ K
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-----------NSRKHKKEKKKRKKSKK 253
Query: 779 THHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWD-- 836
+ E ++P+ T F + P + R +E E +
Sbjct: 254 SASSESEAENLE--AQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECN 311
Query: 837 -PEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG-----TFQRGRGRFNFKKSGSSPKWTHD 890
P P S + L R ++ +GRG T R R R F++S + P W +
Sbjct: 312 PPNSQPASYQRRLLVTRS------GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQE 365
Query: 891 KYQGDGI-VEDEEETMENNEEKKDRRKEEK 919
+ + V E ++ ++ + + KE +
Sbjct: 366 MQRAQRMRVSSGERWIKGDKSELNEIKENQ 395
Score = 33.9 bits (76), Expect = 0.71
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 2 GRSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
GRS S+ R + SRS S+SR+ + + S+S R S S RMYS+ +
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRK-ENSESEKRMYSKSRDHN 672
Query: 61 YRNN 64
NN
Sbjct: 673 SSNN 676
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 73.6 bits (179), Expect = 8e-13
Identities = 164/851 (19%), Positives = 297/851 (34%), Gaps = 153/851 (17%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
S + S SS K S S+SRS S K + S + ++SRS D + ++++
Sbjct: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDH-----HSKEHQR 209
Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS--PRRGRSRSRSPKR---- 117
++ R P + P + +HS P S+S S +
Sbjct: 210 SKSPRDP--------------DANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTA 255
Query: 118 --RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ- 174
R + Q S S S +S P SK+ ++K + + A G+
Sbjct: 256 YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSC 315
Query: 175 ------------------EESPLKSKSQEEPKDTFE-------------HDPSESIDEFN 203
+P K++ + P T E ++PS++ +
Sbjct: 316 VDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQ 375
Query: 204 KSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSH 263
S D+ S + + P +TP S S H+++ +
Sbjct: 376 SKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSH--------HNSEGADNSRDD 427
Query: 264 SIQHSPERSGSGSVGNGSSRYSPSQ-NSPIHHIPSRRSPAKT----------------IA 306
S HS S SGS S S S+ N P P T ++
Sbjct: 428 SSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVS 487
Query: 307 PQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS 366
P ++ + +G +Q T + +TD RD + +KGS
Sbjct: 488 PASSVDSNIPSSQGYKKEGREQGTGNS------YTDTSGPKETSSATPGRDSKTI-QKGS 540
Query: 367 EKGRAEGEWEDQEALDYFSDKES-GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFAT 425
E GR G + D + + + GK++ +E EE + D S +
Sbjct: 541 ESGR--GRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
Query: 426 ASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNS 485
+ H K + KG+R+ + +E K+ RP+ K K+K K+S
Sbjct: 599 SRH------------KAATKGSRKPNIKKESKSSP---------RPTAEKKKYKSTSKSS 637
Query: 486 E--RITVKKETQSPEQVKSEKLKDLFDYSP-PLHKNLDAREKSTFREESPLRIKMIASDS 542
+ R ++ +T S + +SE L P + S E+S R +M +
Sbjct: 638 QKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSP-- 695
Query: 543 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 602
E K ++P+ D P + D L + + KE E P+ K
Sbjct: 696 --MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETE---------PPKGEKKNV 744
Query: 603 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS--PS 660
H +E +++ N+ ++ + ++ K P+ + PS
Sbjct: 745 PE---------KHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPS 795
Query: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK---ERSKERGDSKGSRES 717
+ R+ ++ + KE++ S D + + R++ + S + S ++E+
Sbjct: 796 SNRESSK----QSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKET 851
Query: 718 SGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP---SSREEKESKKERE 774
SGS K + K+ + K S K ++ + SSSS+ PS+P SS+ + +
Sbjct: 852 SGSSKNSSSTSKQKKTEG-KTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDD 910
Query: 775 EEFKTHHEMKE 785
+ H ++E
Sbjct: 911 RNYSADHYLQE 921
Score = 50.8 bits (120), Expect = 6e-06
Identities = 161/803 (20%), Positives = 278/803 (34%), Gaps = 134/803 (16%)
Query: 97 WNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS-------- 148
+ +RH S + + P + SQ+ S + + S R+ SSS ++S
Sbjct: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
Query: 149 PYSKSPVSKRRGSQ-----EKQTKKAEGEPQEESPLKSK----------SQEEPKDTFEH 193
Y+ S S R+ Q K + G+PQ S L S S+E +
Sbjct: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPR 214
Query: 194 DPSESIDE-----FNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
DP + D F+ ++ P L + NS P+ P S P L
Sbjct: 215 DPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS--MLQKPTAYVRPMDGQESME--PKL 270
Query: 249 STVHSAKNT---------PSQHSH----SIQHSP-ERSGSGSVGNGSSRYSPSQNS---P 291
S+ H + + PS +H I P + S SG V +S P
Sbjct: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPP 330
Query: 292 IH--HIPSRRSPAKTIAPQNAPRDESRGR---------------------------SSFY 322
+ H P + P+K P + + G SS
Sbjct: 331 LTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSE 390
Query: 323 PDGGDQETAKT-GKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEAL 381
G+Q+ KT + E S N+RD ++S GSE D E+
Sbjct: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRD-DSSSHSGSESSSG----SDSESE 445
Query: 382 DYFSDKESGKQKFNDSEGDDTEETEDYR--QFRKSVLADQGKSFATASHRNTEEEGLKYK 439
SD E+ + + S + T ++ + V + ++ +G K +
Sbjct: 446 SSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKE 505
Query: 440 SKVSLKGNRESD--GFREEKNYKLKETGYVVERPSTT----KDKHKEEDKNSERITV-KK 492
+ GN +D G +E + +++ S + + + D ++R TV KK
Sbjct: 506 GREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKK 565
Query: 493 ETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVK--LK 550
+ + E+ +E+ + +L + S+ R K S +P +K K
Sbjct: 566 QPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS-------RHKAATKGSRKPNIKKESK 618
Query: 551 MAPVPLDDSNRPASLTKDRLLASTLVH---SVKKEQEFRSIFDHIKLPQ----------- 596
+P P + + S +K + ++ S E S+ + P+
Sbjct: 619 SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKP 678
Query: 597 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR---QKSPEIHR 653
+S +SF + + ++E+ S ++R+ K TR + E
Sbjct: 679 SSVEEEDSFFRQ--RMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
Query: 654 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 713
+ KHTR A ++ K N KG +K + + D R ++ K K K
Sbjct: 737 PKGEKKNVPEKHTREAQKQASEKVSN-KGKRKHK-NEDDNRASESKKPKTEDKNSAGHKP 794
Query: 714 SRESSGSRKQEKTPKDY----------KEYKSYKDDSKHKREQDHS-RSSSSSASPSSPS 762
S S++ KD K+ K+ K Q S +SSS+S +S S
Sbjct: 795 SSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGS 854
Query: 763 SREEKESKKEREEEFKTHHEMKE 785
S+ + K+++ E KT KE
Sbjct: 855 SKNSSSTSKQKKTEGKTSSSSKE 877
Score = 50.4 bits (119), Expect = 7e-06
Identities = 124/571 (21%), Positives = 201/571 (35%), Gaps = 111/571 (19%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
G NSR SS S S S+SSS S S S S S + + S S + + ++ D
Sbjct: 420 GADNSRDDSS-SHSGSESSSGSDSESESSSS--DSEANEPSQSASPEPEPPPTNKWQLDN 476
Query: 62 RNNR--------------GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRR 107
N+ + GY+ GR QG G Y
Sbjct: 477 WLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE--QGTGNSY------------------- 515
Query: 108 GRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
+ + PK S S + R S + S R SP ++RR +KQ K
Sbjct: 516 --TDTSGPKETS-----SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPK 568
Query: 168 KAEGEPQEE--SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRS 225
KAE EE LK +S E P D PS +AT G P + S
Sbjct: 569 KAEKAAAEEPRGGLKIES-ETPVDLASSMPSS-----RHKAATKGSRKPNI-----KKES 617
Query: 226 PHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 285
SP P A S+ S+ S + E S S + S
Sbjct: 618 KSSPRPTAEKKKYKST-----------------SKSSQKSREIIETDTSSSDSDESESLP 660
Query: 286 PSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEES 345
PS +P + S R+P K P + ++S R + ++E L ++ +
Sbjct: 661 PSSQTP-KYPESNRTPVK---PSSVEEEDSFFRQRMFSPMEEKE------LLSPLSEPDD 710
Query: 346 RVFLLDRGNTR---------DKEASKEKGSEKGRAEGEWEDQEALDYFSDKES--GKQKF 394
R L+ + + KE KG +K E +EA S+K S GK+K
Sbjct: 711 RYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEK--HTREAQKQASEKVSNKGKRKH 768
Query: 395 NDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFR 454
+ + + E++ + K+ + S +S ++ +E S +++
Sbjct: 769 KNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEH 828
Query: 455 EEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYS-- 512
+ + ++ + ++ K+ KNS + +K+T+ S+++K+ S
Sbjct: 829 GSRKRTISQSSSLKSSSNSNKET-SGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSS 887
Query: 513 --PPLHKNLDAREKSTFREESPLRIKMIASD 541
PP LD+ P R K++ D
Sbjct: 888 NCPPSAPTLDS--------SKPRRTKLVFDD 910
Score = 38.5 bits (88), Expect = 0.029
Identities = 73/346 (21%), Positives = 120/346 (34%), Gaps = 34/346 (9%)
Query: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
++ S+S R + + K S SSQ+SR SS S S S SS K P S R
Sbjct: 614 KKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR 673
Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS--GDIWPGL 216
+P+K S EE F ++E S S D +P +
Sbjct: 674 ------------------TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLI 715
Query: 217 SAYDNS--PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
D + R P P PP + P T + K + S+ + +
Sbjct: 716 VKIDLNLLTRIPGKPYKETEPPKGEK--KNVPEKHTREAQKQASEKVSNKGKRKHKNEDD 773
Query: 275 GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG 334
+ +NS H S R +K Q+A +++ S P + G
Sbjct: 774 NRASESKKPKTEDKNSAGHKPSSNRESSK----QSAAKEKDLLPSPAGPVPSKDPKTEHG 829
Query: 335 KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKF 394
KR + S + N +SK S + + E + + S + K
Sbjct: 830 S-RKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS----SKEVKEKAPS 884
Query: 395 NDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKS 440
+ S + T D + R++ L +++ +A H E + LK+ +
Sbjct: 885 SSSNCPPSAPTLDSSKPRRTKLVFDDRNY-SADHYLQEAKKLKHNA 929
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 73.2 bits (178), Expect = 1e-12
Identities = 60/186 (32%), Positives = 90/186 (48%), Gaps = 23/186 (12%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
+ S + + K R S RS SRS SR++R+ SRSR R SRSRSR+R SR R+
Sbjct: 43 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102
Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
+ +R R R R R + +R +RS R RSRSR K+R
Sbjct: 103 RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRTRSRSRDRKKRIE 149
Query: 121 SSQR-SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
+R SRS SR + SP R+++ ++ +++R ++ KK + + ++E
Sbjct: 150 KPRRFSRSLSR-----TPSPPPFRGRNTAMDAQEALARRL----ERAKKLQEQREKEMVE 200
Query: 180 KSKSQE 185
K K QE
Sbjct: 201 KQKQQE 206
Score = 55.1 bits (131), Expect = 3e-07
Identities = 54/176 (30%), Positives = 79/176 (44%), Gaps = 23/176 (13%)
Query: 12 RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71
R +S+ +SS + +S H+ K+ S + R R S DR R++ +++RG
Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR----HKRKERKSSRGRSHS- 67
Query: 72 GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRR 131
R R R R HR R R SRS R +SRSRS +R+ +SRSRSR
Sbjct: 68 --RSRSRE-------RRHRSRSRERKKSR-SRSRERKKSRSRSRERK-----KSRSRSRE 112
Query: 132 SYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEP 187
R RS S SR ++ R S+ + KK +P+ S S++ P
Sbjct: 113 RKRRIRSRSRSRSRHR---HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165
Score = 47.0 bits (110), Expect = 8e-05
Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 13/168 (7%)
Query: 629 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 688
N++ S K E ++ + + H+R + S R H+R ER + +++ KK R
Sbjct: 30 NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRS 88
Query: 689 DSADLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 743
S + + R R + RS+ER SR S SR + +T + +S D K +
Sbjct: 89 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT-RSRSRTRSRSRDRKKR 147
Query: 744 REQDHSRSSSSSASPSSPSSR------EEKESKKEREEEFKTHHEMKE 785
E+ S S S +PS P R + +E+ R E K E +E
Sbjct: 148 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 195
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/227 (24%), Positives = 86/227 (37%), Gaps = 37/227 (16%)
Query: 631 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDS 690
R + K H ++ KS + H+ + + ++H+ G ER+ EN +
Sbjct: 3 RTNFFLKQGRRHESKDKSSKKHKSEEHND---KEHSSDKGRERLNSSENGED-------- 51
Query: 691 ADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSR 750
RH +RKER RG S SR S R+ ++ K+ +S RE+ SR
Sbjct: 52 ---RH----KRKERKSSRGRSH-SRSRSRERRHRSRSRERKKSRS------RSRERKKSR 97
Query: 751 SSSSSASPSSPSSREEKESKKEREEEFKTH-HEMKEYSGFAGVSRPR-------GTFFRI 802
S S S SRE K + R H H + S SR R F R
Sbjct: 98 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 157
Query: 803 RGRGRARGVFAGTNTGPNNSNTTFQK----RPKEEEWDPEYTPKSKK 845
R + F G NT + ++ + +E+ + E K K+
Sbjct: 158 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
Score = 40.8 bits (94), Expect = 0.006
Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 17/160 (10%)
Query: 348 FLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE-GDDTEETE 406
F L +G + SK+K S+K ++E E D+E + SDK G+++ N SE G+D
Sbjct: 6 FFLKQGRRHE---SKDKSSKKHKSE-EHNDKE---HSSDK--GRERLNSSENGED----- 51
Query: 407 DYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGY 466
R RK + +G+S + + R + K S +RE R + K
Sbjct: 52 --RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
Query: 467 VVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 506
ER + + + ++ R + T+S + + ++++
Sbjct: 110 SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 149
Score = 34.3 bits (77), Expect = 0.55
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 99 RRHS---RSPRRGRSRSRSPKRRSVSSQRSRSRS---------RRSYRSSRSPRSSSSRS 146
RRH +S ++ +S + K S R R S R+ +SSR S SRS
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 147 SS--PYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188
S+S K+ S+ ++ KK+ +E +S+S+E +
Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,115,077
Number of Sequences: 37866
Number of extensions: 2190272
Number of successful extensions: 37489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 405
Number of HSP's successfully gapped in prelim test: 1104
Number of HSP's that attempted gapping in prelim test: 15459
Number of HSP's gapped (non-prelim): 11759
length of query: 920
length of database: 18,247,518
effective HSP length: 112
effective length of query: 808
effective length of database: 14,006,526
effective search space: 11317273008
effective search space used: 11317273008
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.