BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [Homo sapiens] (1254 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [... 2476 0.0 gi|170784831 chromosome 1 open reading frame 9 protein isoform 2... 2364 0.0 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 46 3e-04 gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 45 4e-04 gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 45 4e-04 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.004 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 0.005 gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 41 0.006 gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 41 0.006 gi|171543895 ataxin 2 [Homo sapiens] 41 0.008 gi|133778961 testis expressed 15 [Homo sapiens] 40 0.011 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 40 0.014 gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] 40 0.014 gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] 40 0.014 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.014 gi|242117996 hypothetical protein LOC392307 [Homo sapiens] 40 0.018 gi|109255234 centrosomal protein 290kDa [Homo sapiens] 40 0.018 gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 40 0.018 gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 40 0.018 gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 40 0.018 gi|109637771 calpastatin isoform l [Homo sapiens] 39 0.024 gi|109637769 calpastatin isoform k [Homo sapiens] 39 0.024 gi|109637767 calpastatin isoform j [Homo sapiens] 39 0.024 gi|109637765 calpastatin isoform i [Homo sapiens] 39 0.024 gi|109637763 calpastatin isoform h [Homo sapiens] 39 0.024 gi|109637761 calpastatin isoform g [Homo sapiens] 39 0.024 gi|109637759 calpastatin isoform f [Homo sapiens] 39 0.024 gi|109637757 calpastatin isoform e [Homo sapiens] 39 0.024 gi|27765085 calpastatin isoform b [Homo sapiens] 39 0.024 gi|109637753 calpastatin isoform a [Homo sapiens] 39 0.024 >gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [Homo sapiens] Length = 1254 Score = 2476 bits (6417), Expect = 0.0 Identities = 1254/1254 (100%), Positives = 1254/1254 (100%) Query: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD Sbjct: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60 Query: 61 EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120 EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES Sbjct: 61 EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120 Query: 121 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS Sbjct: 121 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180 Query: 181 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN Sbjct: 181 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240 Query: 241 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT Sbjct: 241 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300 Query: 301 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ Sbjct: 301 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360 Query: 361 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV Sbjct: 361 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420 Query: 421 KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480 KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP Sbjct: 421 KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480 Query: 481 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP Sbjct: 481 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540 Query: 541 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE Sbjct: 541 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600 Query: 601 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV Sbjct: 601 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660 Query: 661 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE Sbjct: 661 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720 Query: 721 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK Sbjct: 721 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780 Query: 781 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE Sbjct: 781 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840 Query: 841 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA Sbjct: 841 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900 Query: 901 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK Sbjct: 901 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960 Query: 961 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL Sbjct: 961 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020 Query: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK Sbjct: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080 Query: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP Sbjct: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140 Query: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR Sbjct: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200 Query: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI Sbjct: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254 >gi|170784831 chromosome 1 open reading frame 9 protein isoform 2 [Homo sapiens] Length = 1210 Score = 2364 bits (6126), Expect = 0.0 Identities = 1210/1254 (96%), Positives = 1210/1254 (96%), Gaps = 44/1254 (3%) Query: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK Sbjct: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK- 59 Query: 61 EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120 NTESKKLSPPVVETLPTVDLHEES Sbjct: 60 ------------------------------------NTESKKLSPPVVETLPTVDLHEES 83 Query: 121 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS Sbjct: 84 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 143 Query: 181 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN Sbjct: 144 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 203 Query: 241 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT Sbjct: 204 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 263 Query: 301 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ Sbjct: 264 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 323 Query: 361 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV Sbjct: 324 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 383 Query: 421 KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480 K VELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP Sbjct: 384 K-------VELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 436 Query: 481 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP Sbjct: 437 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 496 Query: 541 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE Sbjct: 497 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 556 Query: 601 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV Sbjct: 557 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 616 Query: 661 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE Sbjct: 617 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 676 Query: 721 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK Sbjct: 677 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 736 Query: 781 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE Sbjct: 737 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 796 Query: 841 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA Sbjct: 797 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 856 Query: 901 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK Sbjct: 857 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 916 Query: 961 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL Sbjct: 917 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 976 Query: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK Sbjct: 977 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1036 Query: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP Sbjct: 1037 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1096 Query: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR Sbjct: 1097 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1156 Query: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI Sbjct: 1157 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1210 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 45.8 bits (107), Expect = 3e-04 Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 33/200 (16%) Query: 840 EAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGY 899 E K I D KQ + ++ ++ E+E +D L L + D +L+ T L Sbjct: 256 EYKKEINDKEKQVSLLLI------QITEKENKMKD--LTFLLEESRDKVNQLEEKTKLQS 307 Query: 900 AN-----GNLVHGSNQKESVFMRLNNRI---KALEVNMSLSGRYLEELSQRYRKQMEEMQ 951 N H + + E + + L + KALE ++ ++ + + +L++ QMEE Sbjct: 308 ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367 Query: 952 KA----------FNKTIVKLQNTSRIAEEQDQRQTEAIQLL-------QAQLTNMTQLVS 994 KA F T+ L+ R +++ ++ + +++L ++L MT+L + Sbjct: 368 KARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTN 427 Query: 995 NLSATVAELKREVSDRQSYL 1014 N + ELK+ + ++++ L Sbjct: 428 NKEVELEELKKVLGEKETLL 447 Score = 36.2 bits (82), Expect = 0.20 Identities = 75/391 (19%), Positives = 158/391 (40%), Gaps = 41/391 (10%) Query: 610 ESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLVLAQPPLLLP 669 E ETQ+ S +E+ CS+ L ++ R L K +D L + L Sbjct: 358 EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQR--LEKNEDQLKILTMELQKK 415 Query: 670 AESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTL 729 + S L+ ++ N +E E VLG+ + ++++ + EL+ + + + Sbjct: 416 S-----SELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE--ELKGTEQELI 468 Query: 730 SQSLLLDITPEINPLP--KIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFS-- 785 LL E++ L ++ S +Y + + ++ E++NE + +E S Sbjct: 469 G--LLQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHC 520 Query: 786 ---SIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAK 842 S+E +T ET+ + + N +ED+N+ + K E ++ I + + Sbjct: 521 NKLSLENKELTQETSDMTLELKNQ-QEDINNNK---KQEERMLKQIENLQETETQ----L 572 Query: 843 MNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANG 902 N + ++ L D K EE LR + ELQ G Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNN---LRKQVENKNKYIEELQQENKALKKKG 629 Query: 903 NLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQ 962 +++ +V+ ++ LE+ + + + E++ Y+K++E+ + + + +++ Sbjct: 630 T---AESKQLNVY---EIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVE 683 Query: 963 NTSRIAEEQDQRQTEAIQLLQAQLTNMTQLV 993 IA+E + Q E + Q ++ M L+ Sbjct: 684 KAKVIADEAVKLQKEIDKRCQHKIAEMVALM 714 Score = 32.3 bits (72), Expect = 2.9 Identities = 81/381 (21%), Positives = 147/381 (38%), Gaps = 61/381 (16%) Query: 765 IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI--IKEDVNSMQIFTKL-S 821 + QE EI+++ +Q S + IT + NK+ +L + ++ VN ++ TKL S Sbjct: 253 LEQEYKKEINDKEKQVS-----LLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQS 307 Query: 822 ETIVPPINTA--TVPDNEDGEAKMNIADTAKQTL-----ISVVDSSSLPEVKEEEQSPED 874 E + I + ED + + + + ++ L I+ L E KE + + Sbjct: 308 ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367 Query: 875 ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGR 934 T+F + + +L ++ + +++K L + + Sbjct: 368 KARAAHSFVVTEFETTVCSLEEL----------LRTEQQRLEKNEDQLKILTMELQKKSS 417 Query: 935 YLEE---LSQRYRKQMEEMQKAFNKTIVKLQNTS---RIAEEQDQRQTEAIQLLQA---- 984 LEE L+ ++EE++K + L +IAEE + E I LLQA Sbjct: 418 ELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKE 477 Query: 985 ------QLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQ 1038 QLT +T S V +LK E+ + + C L L + +Q Sbjct: 478 VHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSL-----ENKELTQ 532 Query: 1039 FDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVE 1098 D +L + D N K++ L + ++LQ T ++ Y+ E Sbjct: 533 ETSDMTLELKNQQE-----------DINNNKKQEERMLKQIENLQETETQLRNELEYVRE 581 Query: 1099 PLKFSPEKKKKRCKYKIEKIE 1119 LK +K+ K K++K E Sbjct: 582 ELK----QKRDEVKCKLDKSE 598 >gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sapiens] Length = 1782 Score = 45.1 bits (105), Expect = 4e-04 Identities = 65/287 (22%), Positives = 118/287 (41%), Gaps = 56/287 (19%) Query: 50 ENEDVQFQKKDEREGPINAESLGKSGSNLPISPKE--HKLK------------DDSIVDV 95 E E + +++ + + +E L S P P E H+ + ++ + Sbjct: 329 EQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGS 388 Query: 96 QNTESKKLSPPVVETLPT-VDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSG 154 Q +K +P E +++H+E A V TVE + +E+ E +G Sbjct: 389 QGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVE--------ETAG 440 Query: 155 TIPI-------AKPSETEQSET------DCDVGEALDASAPIEQPSFV--SPPDSLVGQH 199 ++P A+P E E ++ C GE A + V PP+ +V + Sbjct: 441 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE- 499 Query: 200 IENVSSSHG---KGKITKSEFES----KVSASEQ----GGGDPKSALNASDNLKNESSDY 248 +E +SS +G K F S K+S +Q GGGD +S + + S Sbjct: 500 VEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQE 559 Query: 249 TKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNG 295 + G+ +S +SP++PE+I + K + EV+++ A+S+G Sbjct: 560 EQKGE---SSASSPEEPEEITCLE---KGLAEVQQDGEAEEGATSDG 600 >gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sapiens] Length = 1684 Score = 45.1 bits (105), Expect = 4e-04 Identities = 65/287 (22%), Positives = 118/287 (41%), Gaps = 56/287 (19%) Query: 50 ENEDVQFQKKDEREGPINAESLGKSGSNLPISPKE--HKLK------------DDSIVDV 95 E E + +++ + + +E L S P P E H+ + ++ + Sbjct: 231 EQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGS 290 Query: 96 QNTESKKLSPPVVETLPT-VDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSG 154 Q +K +P E +++H+E A V TVE + +E+ E +G Sbjct: 291 QGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVE--------ETAG 342 Query: 155 TIPI-------AKPSETEQSET------DCDVGEALDASAPIEQPSFV--SPPDSLVGQH 199 ++P A+P E E ++ C GE A + V PP+ +V + Sbjct: 343 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE- 401 Query: 200 IENVSSSHG---KGKITKSEFES----KVSASEQ----GGGDPKSALNASDNLKNESSDY 248 +E +SS +G K F S K+S +Q GGGD +S + + S Sbjct: 402 VEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQE 461 Query: 249 TKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNG 295 + G+ +S +SP++PE+I + K + EV+++ A+S+G Sbjct: 462 EQKGE---SSASSPEEPEEITCLE---KGLAEVQQDGEAEEGATSDG 502 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 42.0 bits (97), Expect = 0.004 Identities = 56/281 (19%), Positives = 105/281 (37%), Gaps = 4/281 (1%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91 +SS S++S S D + + ++ D D + +++S S S+ + DS Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081 Query: 92 IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIE 151 +++S S + + S+ DS N S SS S + S D Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSN 1140 Query: 152 KSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK 211 S + ++ S++ S D ++ D+S + + DS + S S Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200 Query: 212 ITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTF 271 + S S S S S+ ++ + NESSD + D +S +S D D Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS--DSSDSSDS 1258 Query: 272 DEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYAS 312 + + +S+S + ++NG + + N+ S Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299 Score = 40.4 bits (93), Expect = 0.011 Identities = 62/314 (19%), Positives = 118/314 (37%), Gaps = 24/314 (7%) Query: 33 SSASASSYYSQD-DNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91 S +++ Y S D D+ +++ +D + N+ES S S S + KD+ Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502 Query: 92 IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIE 151 ++SK ++ T D + SN ++ +N S S + S D + Sbjct: 503 ----NGSDSKGAEDDDSDS--TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556 Query: 152 KSGTIPIAKPSETEQSET---------DCDVGEALDASAPIEQPSFVSPPDSLVGQHIEN 202 S + + S+++ S++ D D ++ D+ + S S S ++ Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616 Query: 203 VSSSHGKGKITKSEFES-----KVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPT 257 SS K +KSE +S K +S+ D ++SD+ N S+ D + Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS-SNSSNSSDSSDSSDSS 675 Query: 258 SVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVECGA 317 +S D + + D E S S +S + S ++ N ++ S Sbjct: 676 DSSSSSDSSN--SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733 Query: 318 KILAANPEAKSTSA 331 ++N S S+ Sbjct: 734 SSDSSNSSDSSDSS 747 Score = 40.0 bits (92), Expect = 0.014 Identities = 43/231 (18%), Positives = 89/231 (38%), Gaps = 4/231 (1%) Query: 31 ESSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDD 90 +SS +S SS S N + N+ + ++ + S + S + D Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825 Query: 91 SIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEI 150 S +++S S + + +SSN S + ++ SS +S + S + Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885 Query: 151 EKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKG 210 +S + S + +D D ++ ++S + + +S N S S Sbjct: 886 NESSN---SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942 Query: 211 KITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVAS 261 + S +S S+ D ++ ++SD+ ++SSD + D +S +S Sbjct: 943 DSSDSS-DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Score = 38.5 bits (88), Expect = 0.041 Identities = 49/271 (18%), Positives = 104/271 (38%), Gaps = 15/271 (5%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91 S S+S+S + D+ + + D + + S SN S + DS Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734 Query: 92 IVDVQNTESKKLSPPVVETLPTVDLHE-----ESSNAVVDSETVENISSSSTSEITPISK 146 D N+ S + + D + +SS++ S++ ++ +SS +++ + S Sbjct: 735 S-DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793 Query: 147 LDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSS 206 + S + S +D D + D+S + + DS ++ SS Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS-----SDSSDSS 848 Query: 207 HGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPE 266 G + + +S S+ D ++ ++SD+ ++S++ + D +S +S D Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS--SDSNESSNSSDSSDSSNSSDSDSS 906 Query: 267 DIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 297 D + + S+S ++S N S Sbjct: 907 DSSNSSD--SSDSSNSSDSSESSNSSDNSNS 935 Score = 37.4 bits (85), Expect = 0.091 Identities = 54/271 (19%), Positives = 102/271 (37%), Gaps = 7/271 (2%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91 SSS S SS D+ ++ D D + +++S S S+ S D S Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSS-NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634 Query: 92 IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPIS-KLDEI 150 D ++ S S + + D SSN+ S++ ++ SSS+S+ + S D Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSD-SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693 Query: 151 EKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKG 210 + S + + S++ S++ + S+ + + DS + S S Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Query: 211 KITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGD----IDPTSVASPKDPE 266 + S S S S S+ +++ + N+SS+ + D D ++ + D Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813 Query: 267 DIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 297 D D + S S ++S + S Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844 Score = 35.4 bits (80), Expect = 0.34 Identities = 49/288 (17%), Positives = 104/288 (36%), Gaps = 11/288 (3%) Query: 31 ESSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKS----GSNLPISPKEHK 86 +S+S+ +S D+ N D + +++S S S+ S + Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703 Query: 87 LKDDSIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISK 146 D S D ++ S +SSN+ S++ ++ +SS +S+ + S Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Query: 147 L----DEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIEN 202 D + S + + S++ S D ++ ++S DS + Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 203 VSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLK-NESSDYTKPGDIDPTSVAS 261 SS+ S +S+ G + N SD+ ++SSD + + +S +S Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883 Query: 262 PKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNN 309 D + + + + S S ++S + S + ++ N+ Sbjct: 884 --DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/292 (19%), Positives = 115/292 (39%), Gaps = 28/292 (9%) Query: 751 ESVEYEAGHIPSPVIPQESSVEIDNET-EQKSESFSSIEKPSITYETNKVNELMDNIIKE 809 E +E E + + + V++ +T Q E E ++ ETNK+ +++ Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288 Query: 810 DVNSMQIFTKLSETIVPPINTATVPDNE-----DGEAKMNIADTAK-----QTLISVVDS 859 D+ MQ + E + P+ A +E E K+ D + Q L+S Sbjct: 1289 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKD 1348 Query: 860 SSLPEVKE--EEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHG--------SN 909 E ++ E+ ++ L AE+ S N NL+ Sbjct: 1349 PDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRT 1408 Query: 910 QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 969 +KE++ L+ +I ++ + + ++++ +RY+ Q EE++ +K + +S + Sbjct: 1409 EKETIQKDLDAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQ 1467 Query: 970 EQD------QRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015 EQ Q E + + + ++ V NL T++E + E + Q V Sbjct: 1468 EQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTV 1519 Score = 37.7 bits (86), Expect = 0.069 Identities = 98/503 (19%), Positives = 186/503 (36%), Gaps = 104/503 (20%) Query: 529 ENATATAAPKMPE-STPVSTPVPSP-----EYVTTEVHTHDMEPSTPDTPKESPIVQLVQ 582 ++ + + PK P S VSTP P P E + + ++ + KE + +Q Sbjct: 634 DDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQ 693 Query: 583 EEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVA 642 E+ E VT L S+ T I F+ Y+ V Sbjct: 694 NEQLEKLQEQVTDLR--------------------SQNTKISTQLDFASKRYEMLQDNVE 733 Query: 643 LYRQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSG--------ELENTNIEREA 694 YR+ + + + Q E + ++ Q L G E+ N+++E Sbjct: 734 GYRREITSLHERNQKLTATTQ-----KQEQIINTMTQDLRGANEKLAVAEVRAENLKKEK 788 Query: 695 ETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVE 754 E + L ++ S ++ L+ ++ Q+LLL I + +E SE+ Sbjct: 789 EMLKLSEVRLSQQRESLL-------------AEQRGQNLLLTNLQTIQGI--LERSET-- 831 Query: 755 YEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSM 814 E+ + ++ E+ S ++K + E + + L N+ DV + Sbjct: 832 -------------ETKQRLSSQIEKLEHEISHLKK-KLENEVEQRHTLTRNL---DVQLL 874 Query: 815 QIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTL----ISVVDSSSLPEVKEEEQ 870 +L +NT + N A+ IA T KQ L + V SS K + Sbjct: 875 DTKRQLDTETNLHLNTKELLKN----AQKEIA-TLKQHLSNMEVQVASQSSQRTGKGQPS 929 Query: 871 SPED-----ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKAL 925 + ED + LR + D L+ ST SN ++ M + +L Sbjct: 930 NKEDVDDLVSQLRQTEEQVNDLKERLKTST------------SNVEQYQAM-----VTSL 972 Query: 926 EVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQ 985 E +++ + EE+ + +++E + + KL + +E + AI+ ++ Q Sbjct: 973 EESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQ 1032 Query: 986 LTNMTQLVSNLSATVAELKREVS 1008 L+ + + +S++ V E + S Sbjct: 1033 LSELKKTLSSVQNEVQEALQRAS 1055 >gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] Length = 1280 Score = 41.2 bits (95), Expect = 0.006 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%) Query: 837 EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 896 ++G + +++++ + V + + ++ + + A + ++RTA Q D Sbjct: 1054 QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 1113 Query: 897 LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 956 + NL + + + I L+ + +S R LEE +R Q ++MQK + Sbjct: 1114 VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1168 Query: 957 TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014 +L+++ R+ +Q+++ ++ M ++S L A ELK++ ++ Q+ + Sbjct: 1169 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1216 >gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] Length = 1139 Score = 41.2 bits (95), Expect = 0.006 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%) Query: 837 EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 896 ++G + +++++ + V + + ++ + + A + ++RTA Q D Sbjct: 913 QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 972 Query: 897 LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 956 + NL + + + I L+ + +S R LEE +R Q ++MQK + Sbjct: 973 VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1027 Query: 957 TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014 +L+++ R+ +Q+++ ++ M ++S L A ELK++ ++ Q+ + Sbjct: 1028 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1075 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 40.8 bits (94), Expect = 0.008 Identities = 54/199 (27%), Positives = 80/199 (40%), Gaps = 21/199 (10%) Query: 77 NLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSS 136 N P KE+ +++ E+K +SP V E +D ++ N + S Sbjct: 757 NSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDF-------RLQPS 809 Query: 137 STSEITP--ISKLDEIEKSGTI------PIAKPSETEQSETDCDVGEALDASAPIEQPSF 188 STSE ++K E EKS + P AK S E S ++C G + ++P PS Sbjct: 810 STSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSS-KPNSPSISPSI 868 Query: 189 VSPPDSLVGQHI--ENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESS 246 +S + G + + V +S K K + E K A+EQ KS LN + N S Sbjct: 869 LSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQ---VRKSTLNPNAKEFNPRS 925 Query: 247 DYTKPGDIDPTSVASPKDP 265 PTS P Sbjct: 926 FSQPKPSTTPTSPRPQAQP 944 >gi|133778961 testis expressed 15 [Homo sapiens] Length = 2789 Score = 40.4 bits (93), Expect = 0.011 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 52/229 (22%) Query: 100 SKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITP----ISKLDEIEKSGT 155 SKK S P + D ESS + +D + + + S + S P + E+ K+ Sbjct: 1329 SKKYSIPQLSAAAVTDSEGESSKSYLDKQRILTVDSFAASSTVPHCEQSCREKELLKTEQ 1388 Query: 156 IPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 T+ +ET+ LD ++ E+ D G++I +SSS Sbjct: 1389 CSSGNCLHTDGNETNVTENYELDVASGTEE-------DKSYGENIVELSSS--------- 1432 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWK 275 S+L DN+K SS+ + KD ED T+ Sbjct: 1433 ----------------DSSLLLKDNVKGSSSE----------TCIVKKDTEDRITW---- 1462 Query: 276 KKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVEC-GAKILAAN 323 KV + EK K S GS + + +N + C KI+ N Sbjct: 1463 -KVKQAEKAKDSVYKRSMTEGSTVNTEYKNQKNQISEESCLNEKIITTN 1510 Score = 33.5 bits (75), Expect = 1.3 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 17/159 (10%) Query: 1102 FSPEKKKKRCKYKIEK----IETIKPEEPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSS 1157 ++ K KK + +I K I + P + I GRK +D S E + S Sbjct: 903 YNDTKNKKEVESRISKRKLHISSRDQNIPHKDLRRHKIYGRKRRLTSQDSS---ECFSSL 959 Query: 1158 YKGPPSEGSSETSSQSEE---SYFCGISACTSLCNGQSQKTKTEKRA--LKRRRSKVQDQ 1212 S+G +T SQSE+ S +S SLC + K +K LK+ +V Sbjct: 960 -----SQGRIKTFSQSEKHIKSVLNILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTS 1014 Query: 1213 GKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVS 1251 +LI + + + G LP + II N + G ++VS Sbjct: 1015 LQLITKVGEERKGPLPKSYAIICNNFWESCDLQGYSSVS 1053 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 40.0 bits (92), Expect = 0.014 Identities = 118/595 (19%), Positives = 224/595 (37%), Gaps = 77/595 (12%) Query: 667 LLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMH--QDDLVNHTVDAVELEPS 724 LL ++S+L+ +L E ET VL L H Q+ + T S Sbjct: 531 LLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590 Query: 725 HSQTLSQSLLLDITPEINPLPKIEVSE--SVEYEAGHIPSPVIPQESSV-EIDNETEQKS 781 H Q +Q L D E + S+E + S + + V ++D + + K+ Sbjct: 591 HKQ--AQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKT 648 Query: 782 ESFSSIEKPSITY--------------------ETNKVNELMDNIIKE----DVNSMQIF 817 E S E E NK+ +D + + + Q+ Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE 708 Query: 818 TKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALL 877 + L E ++ + +G+ K AD+ + + +L +++++ Q D L Sbjct: 709 SHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE---VKASKEQALQDLQQQRQLNTDLEL 765 Query: 878 RGLQRTAT-DFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYL 936 R + + + E+ +ST L +L S ES+ +L + E + + Sbjct: 766 RATELSKQLEMEKEIVSSTRL-----DLQKKSEALESIKQKLTKQ----EEEKQILKQDF 816 Query: 937 EELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNL 996 E LSQ + Q EE+ T+ +LQ ++ E++ TE L ++++ +L Sbjct: 817 ETLSQETKIQHEELNNRIQTTVTELQ---KVKMEKEALMTE----LSTVKDKLSKVSDSL 869 Query: 997 SATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSP 1056 + +E ++E ++ ++ C L L +Q NT + + L K + Sbjct: 870 KNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ-MENTLKEQKELKKSLEKEKEASHQ 928 Query: 1057 -KRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKI 1115 K +S + ++ + + + QL G + LK S E+KKK Sbjct: 929 LKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN---------INELKQSSEQKKK------ 973 Query: 1116 EKIETIKPEEPLHPIANGDIKGR-KPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSE 1174 +IE ++ E + + +++ + + Q E S E S ET Q + Sbjct: 974 -QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032 Query: 1175 ESYFCGISACTSLCNGQSQKTKTEKRALKR-----RRSKVQDQGKLIKTLIQTKS 1224 ++ S L Q K+ EK +L + R+++ +Q KLI+ L K+ Sbjct: 1033 SDFYGRESEL--LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085 Score = 36.6 bits (83), Expect = 0.15 Identities = 58/325 (17%), Positives = 125/325 (38%), Gaps = 35/325 (10%) Query: 720 ELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI-DNETE 778 EL+ S Q Q L +I L K E+ ++ + + ++ + + N E Sbjct: 963 ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022 Query: 779 QKSESFSSIEKPSITYETNKVNELMD--------NIIKEDVNSMQIFTKLSETIVPPINT 830 + E+F ++ E+ + D ++ +ED+ S + ++ + T Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKT 1082 Query: 831 ATVPDNEDGEAKMN--------IADTAKQTLIS----VVDSSSLPEVKEEEQSPEDALLR 878 A +D K + D K+ + V + S L E++E + E + + Sbjct: 1083 AKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142 Query: 879 GLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEE 938 + + ++ T+L A L+ QK + L + +L+ + R + Sbjct: 1143 LNEELKSHKLESIKEITNLKDAKQLLIQ---QK----LELQGKADSLKAAVEQEKRNQQI 1195 Query: 939 LSQRYRKQMEEMQKAFNKTIVKLQNT-------SRIAEEQDQRQTEAIQLLQAQLTNMTQ 991 L + +K+ EE++K F + KL + + EE + + T I L L + + Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255 Query: 992 LVSNLSATVAELKREVSDRQSYLVI 1016 + V+EL+++ D + + + Sbjct: 1256 EWQSSQRRVSELEKQTDDLRGEIAV 1280 Score = 31.2 bits (69), Expect = 6.5 Identities = 49/247 (19%), Positives = 92/247 (37%), Gaps = 34/247 (13%) Query: 795 ETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLI 854 E +V LMDN+ E + KL + + + + + +A ++ + Sbjct: 229 ELVQVQTLMDNMTLERERESE---KLKDECKKLQSQYASSEATISQLRSELAKGPQEVAV 285 Query: 855 SVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESV 914 V + L E L L + D+ + + + N+ +QK+ Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD 345 Query: 915 FMRLNNRIKALE-------VNMSLSG----RYLEELS----------------QRYRKQM 947 +L +R+ A E V +S G + EELS Q+ R++ Sbjct: 346 CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEK 405 Query: 948 E----EMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAEL 1003 E ++Q N+ KL T R E R E QL +L + Q V++L ++ L Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL 465 Query: 1004 KREVSDR 1010 + ++ ++ Sbjct: 466 EEQLKEK 472 >gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] Length = 475 Score = 40.0 bits (92), Expect = 0.014 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%) Query: 866 KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 924 KEE+ + LL LQ + A LQ+ NL+H + QKE +L ++KA Sbjct: 251 KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299 Query: 925 LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 974 ++ LE +LSQ ++ EE+++ N+ +++ + +Q Sbjct: 300 TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359 Query: 975 QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014 + A++ ++ +++++TQ + T+A K SD + L Sbjct: 360 YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399 >gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] Length = 495 Score = 40.0 bits (92), Expect = 0.014 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%) Query: 866 KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 924 KEE+ + LL LQ + A LQ+ NL+H + QKE +L ++KA Sbjct: 251 KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299 Query: 925 LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 974 ++ LE +LSQ ++ EE+++ N+ +++ + +Q Sbjct: 300 TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359 Query: 975 QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014 + A++ ++ +++++TQ + T+A K SD + L Sbjct: 360 YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 40.0 bits (92), Expect = 0.014 Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 7/170 (4%) Query: 842 KMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 901 K+ + DT + + + SSLP V++E+ S E + + D EL+++ G + Sbjct: 612 KVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKS 671 Query: 902 GNLVHGSNQ-KESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960 + V Q + RL ++I LE+N + E+ K++ + + + Sbjct: 672 LSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKN 731 Query: 961 LQNTS----RIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKRE 1006 N S ++EE+DQ ++ +L + +T + V L +AE +R+ Sbjct: 732 ADNNSSAFTALSEERDQLLSQVKEL--SMVTELRAQVKQLEMNLAEAERQ 779 Score = 36.2 bits (82), Expect = 0.20 Identities = 45/230 (19%), Positives = 93/230 (40%), Gaps = 26/230 (11%) Query: 795 ETNKVNELMDNIIKEDVNSMQIFTKLSE------TIVPPINTATVPDNEDGEAKMNIADT 848 E + +N+L++ K N+ FT LSE + V ++ T + + +MN+A+ Sbjct: 717 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEA 776 Query: 849 AKQTLISVVDSSSLPEVKEE-------EQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 901 +Q + ++ + E E +D + LQ D + + L Sbjct: 777 ERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTL---I 833 Query: 902 GNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK- 960 +L KES + R++ + +EELSQ ++ E+ K + K Sbjct: 834 RSLQSQLQNKESEVLEGAERVRHISSK-------VEELSQALSQKELEITKMDQLLLEKK 886 Query: 961 --LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVS 1008 ++ + EE+DQ+ TE + ++ + + +L + LK +++ Sbjct: 887 RDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 936 Score = 32.0 bits (71), Expect = 3.8 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 10/88 (11%) Query: 934 RYLEELSQ------RYRKQMEEMQKAFNKTI----VKLQNTSRIAEEQDQRQTEAIQLLQ 983 +Y E+L+Q +KQ+ E+Q NK + KL+ + +EE ++ + LQ Sbjct: 2535 QYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2594 Query: 984 AQLTNMTQLVSNLSATVAELKREVSDRQ 1011 + ++++ + +L ++++L R+V+ Q Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVTALQ 2622 Score = 31.2 bits (69), Expect = 6.5 Identities = 33/156 (21%), Positives = 68/156 (43%), Gaps = 8/156 (5%) Query: 850 KQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN 909 K+ L+ ++S ++ E + E + LQ+ +N ++ ++V Sbjct: 1583 KEKLVKEIESLKSSKIAESTEWQEKH--KELQKEYEILLQSYENVSNEAERIQHVVEAVR 1640 Query: 910 QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 969 Q++ L ++++ E N + + L+E Q + E+M+K F K+ K Q + E Sbjct: 1641 QEKQ---ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK-FAKS--KQQKILELEE 1694 Query: 970 EQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKR 1005 E D+ + E M L+S+ ++ EL+R Sbjct: 1695 ENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER 1730 >gi|242117996 hypothetical protein LOC392307 [Homo sapiens] Length = 402 Score = 39.7 bits (91), Expect = 0.018 Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 21/137 (15%) Query: 518 EDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD--MEPSTPDTPKES 575 EDL E + S S +T+ + T S VPSP + E H+ + EPS +TP E+ Sbjct: 28 EDLQENHISESFLKPSTSETPLEPHTSESPLVPSPSQIPLEAHSPETHQEPSISETPSET 87 Query: 576 PI--------VQLVQEEEEEASPST--VTLLGSGE--QEDESS-------PWFESETQIF 616 P + +V E+ P + L S + +ED SS PW T + Sbjct: 88 PTYEASLDSPISVVPEKHLTLPPQSRDYVCLSSSDTLKEDLSSESSSNEVPWTRRSTHLS 147 Query: 617 CSELTTICCISSFSEYI 633 SE C+S S + Sbjct: 148 ESESLPEHCLSGPSSQV 164 >gi|109255234 centrosomal protein 290kDa [Homo sapiens] Length = 2479 Score = 39.7 bits (91), Expect = 0.018 Identities = 74/368 (20%), Positives = 156/368 (42%), Gaps = 35/368 (9%) Query: 656 KDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNH- 714 KD +++ + L E ++S L ++E+ N E E L + + Q+ + + Sbjct: 982 KDNMLVQRTSNLEHLECENIS----LKEQVESINKELEITKEKLHTIEQAWEQETKLGNE 1037 Query: 715 -TVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI 773 ++D + ++S +S S + + E+ L + + +E + H+ + + E E Sbjct: 1038 SSMDKAKKSITNSDIVSISKKITML-EMKELNERQRAEHCQKMYEHLRTSLKQME---ER 1093 Query: 774 DNETEQKSESFSSIEKPSITYETNKVNELMDNIIK--EDVNSMQIFTKLSETIVPPINTA 831 + E E K + I + E +EL D++ K D + +I + + + Sbjct: 1094 NFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVS 1153 Query: 832 TVPDNED-GEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAE 890 + + D ++ I + +Q+ V+S + + + QS E +L+ L + + Sbjct: 1154 KLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSL--Q 1211 Query: 891 LQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNM---SLSGR----YLEELSQRY 943 L +T LG ++ + E+ +RL ++ E + L GR +L + Q Sbjct: 1212 LSEATALGKLE-SITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSL 1270 Query: 944 RKQME-----EMQKAFNKTIVKLQNTS-RIAEEQDQRQTEAIQL------LQAQLTNMTQ 991 R+Q Q+ F+KT+++LQN +I +E Q E + ++ +L + + Sbjct: 1271 RRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEE 1330 Query: 992 LVSNLSAT 999 L+S L T Sbjct: 1331 LISTLKDT 1338 >gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo sapiens] Length = 1133 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 776 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 513 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563 Query: 836 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616 Query: 896 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674 Query: 956 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 675 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731 Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 732 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788 Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101 R S P + SK +Q + +P D + PL+ Sbjct: 789 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819 >gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo sapiens] Length = 893 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 776 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 273 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 323 Query: 836 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 324 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 376 Query: 896 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 377 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 434 Query: 956 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 435 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 491 Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 492 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 548 Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101 R S P + SK +Q + +P D + PL+ Sbjct: 549 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 579 >gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo sapiens] Length = 1135 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 776 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 513 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563 Query: 836 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616 Query: 896 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674 Query: 956 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 675 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731 Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 732 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788 Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101 R S P + SK +Q + +P D + PL+ Sbjct: 789 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819 >gi|109637771 calpastatin isoform l [Homo sapiens] Length = 654 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 182 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 240 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 350 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 351 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 404 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 405 KEKAKEEDREK 415 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 403 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 462 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 463 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 522 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 523 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 582 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 583 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 636 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 637 KAKDSAKTTEETSKPK 652 >gi|109637769 calpastatin isoform k [Homo sapiens] Length = 673 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 201 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 259 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 260 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 319 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 320 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 369 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 370 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 423 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 424 KEKAKEEDREK 434 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 422 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 481 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 482 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 541 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 542 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 601 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 602 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 655 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 656 KAKDSAKTTEETSKPK 671 >gi|109637767 calpastatin isoform j [Homo sapiens] Length = 667 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 195 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 253 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 254 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 313 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 314 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 363 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 364 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 417 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 418 KEKAKEEDREK 428 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 416 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 475 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 476 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 535 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 536 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 595 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 596 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 649 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 650 KAKDSAKTTEETSKPK 665 >gi|109637765 calpastatin isoform i [Homo sapiens] Length = 708 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 236 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 294 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 295 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 354 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 355 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 404 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 405 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 458 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 459 KEKAKEEDREK 469 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 457 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 516 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 517 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 576 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 577 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 636 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 637 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 690 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 691 KAKDSAKTTEETSKPK 706 >gi|109637763 calpastatin isoform h [Homo sapiens] Length = 769 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 297 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 355 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 356 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 415 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 416 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 465 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 466 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 519 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 520 KEKAKEEDREK 530 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 518 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 577 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 578 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 637 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 638 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 697 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 698 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 751 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 752 KAKDSAKTTEETSKPK 767 >gi|109637761 calpastatin isoform g [Homo sapiens] Length = 772 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 300 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 358 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 359 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 418 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 419 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 468 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 469 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 522 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 523 KEKAKEEDREK 533 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 521 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 580 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 581 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 640 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 641 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 700 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 701 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 754 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 755 KAKDSAKTTEETSKPK 770 >gi|109637759 calpastatin isoform f [Homo sapiens] Length = 750 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 278 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 336 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 337 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 396 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 397 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 446 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 447 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 500 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 501 KEKAKEEDREK 511 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 499 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 558 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 559 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 618 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 619 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 678 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 679 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 732 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 733 KAKDSAKTTEETSKPK 748 >gi|109637757 calpastatin isoform e [Homo sapiens] Length = 756 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 284 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 342 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 343 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 402 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 403 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 452 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 453 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 506 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 507 KEKAKEEDREK 517 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 505 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 564 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 565 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 624 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 625 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 684 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 685 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 738 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 739 KAKDSAKTTEETSKPK 754 >gi|27765085 calpastatin isoform b [Homo sapiens] Length = 686 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 214 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 272 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 273 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 332 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 333 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 382 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 383 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 436 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 437 KEKAKEEDREK 447 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 435 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 494 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 495 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 554 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 555 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 614 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 615 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 668 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 669 KAKDSAKTTEETSKPK 684 >gi|109637753 calpastatin isoform a [Homo sapiens] Length = 791 Score = 39.3 bits (90), Expect = 0.024 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 42 SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101 S D C + +K+E + A+S G S P K+ K++ D++ D Q E+ Sbjct: 319 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 377 Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156 S + P +DL +E A E +E + + +K G Sbjct: 378 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 437 Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215 P KP +SE ++ E D S E+PS + E S S Sbjct: 438 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 487 Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274 E + S P+ A LK D D DPED P D+ Sbjct: 488 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 541 Query: 275 KKKVMEVEKEK 285 K+K E ++EK Sbjct: 542 KEKAKEEDREK 552 Score = 32.7 bits (73), Expect = 2.2 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%) Query: 58 KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117 K E+ + E LG+ +P + ++KD + ESK+ PP+ E L Sbjct: 540 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 599 Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163 E+ S A SE V +S+T P + +K + K S+ Sbjct: 600 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 659 Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214 + Q + D D + ++ A E + D + ++ +G+ K TK Sbjct: 660 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 719 Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269 +SK A +Q GD S + ++ +N + D K + +S K P++ Sbjct: 720 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 773 Query: 270 TFDEWKKKVMEVEKEK 285 + K E K K Sbjct: 774 KAKDSAKTTEETSKPK 789 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.126 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,272,532 Number of Sequences: 37866 Number of extensions: 2231234 Number of successful extensions: 10009 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 296 Number of HSP's that attempted gapping in prelim test: 9279 Number of HSP's gapped (non-prelim): 1053 length of query: 1254 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1140 effective length of database: 13,930,794 effective search space: 15881105160 effective search space used: 15881105160 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.