Guide to the Human Genome
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Search of human proteins with 7656940

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7656940 chromosome 1 open reading frame 9 protein isoform 1
[Homo sapiens]
         (1254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [...  2476   0.0  
gi|170784831 chromosome 1 open reading frame 9 protein isoform 2...  2364   0.0  
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              46   3e-04
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    45   4e-04
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    45   4e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    42   0.004
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    42   0.005
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]     41   0.006
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]       41   0.006
gi|171543895 ataxin 2 [Homo sapiens]                                   41   0.008
gi|133778961 testis expressed 15 [Homo sapiens]                        40   0.011
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             40   0.014
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           40   0.014
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]           40   0.014
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    40   0.014
gi|242117996 hypothetical protein LOC392307 [Homo sapiens]             40   0.018
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 40   0.018
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    40   0.018
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom...    40   0.018
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    40   0.018
gi|109637771 calpastatin isoform l [Homo sapiens]                      39   0.024
gi|109637769 calpastatin isoform k [Homo sapiens]                      39   0.024
gi|109637767 calpastatin isoform j [Homo sapiens]                      39   0.024
gi|109637765 calpastatin isoform i [Homo sapiens]                      39   0.024
gi|109637763 calpastatin isoform h [Homo sapiens]                      39   0.024
gi|109637761 calpastatin isoform g [Homo sapiens]                      39   0.024
gi|109637759 calpastatin isoform f [Homo sapiens]                      39   0.024
gi|109637757 calpastatin isoform e [Homo sapiens]                      39   0.024
gi|27765085 calpastatin isoform b [Homo sapiens]                       39   0.024
gi|109637753 calpastatin isoform a [Homo sapiens]                      39   0.024

>gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [Homo
            sapiens]
          Length = 1254

 Score = 2476 bits (6417), Expect = 0.0
 Identities = 1254/1254 (100%), Positives = 1254/1254 (100%)

Query: 1    MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60
            MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD
Sbjct: 1    MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60

Query: 61   EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120
            EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES
Sbjct: 61   EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120

Query: 121  SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180
            SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS
Sbjct: 121  SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180

Query: 181  APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240
            APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN
Sbjct: 181  APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240

Query: 241  LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300
            LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT
Sbjct: 241  LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300

Query: 301  KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360
            KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ
Sbjct: 301  KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360

Query: 361  VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420
            VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV
Sbjct: 361  VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420

Query: 421  KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480
            KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP
Sbjct: 421  KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480

Query: 481  LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540
            LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP
Sbjct: 481  LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540

Query: 541  ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600
            ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE
Sbjct: 541  ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600

Query: 601  QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660
            QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV
Sbjct: 601  QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660

Query: 661  LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720
            LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE
Sbjct: 661  LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720

Query: 721  LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780
            LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK
Sbjct: 721  LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780

Query: 781  SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840
            SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE
Sbjct: 781  SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840

Query: 841  AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900
            AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA
Sbjct: 841  AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900

Query: 901  NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960
            NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK
Sbjct: 901  NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960

Query: 961  LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020
            LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL
Sbjct: 961  LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020

Query: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080
            CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK
Sbjct: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080

Query: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140
            SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP
Sbjct: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140

Query: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200
            FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR
Sbjct: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200

Query: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254
            ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI
Sbjct: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254


>gi|170784831 chromosome 1 open reading frame 9 protein isoform 2
            [Homo sapiens]
          Length = 1210

 Score = 2364 bits (6126), Expect = 0.0
 Identities = 1210/1254 (96%), Positives = 1210/1254 (96%), Gaps = 44/1254 (3%)

Query: 1    MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60
            MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK 
Sbjct: 1    MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK- 59

Query: 61   EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120
                                                NTESKKLSPPVVETLPTVDLHEES
Sbjct: 60   ------------------------------------NTESKKLSPPVVETLPTVDLHEES 83

Query: 121  SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180
            SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS
Sbjct: 84   SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 143

Query: 181  APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240
            APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN
Sbjct: 144  APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 203

Query: 241  LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300
            LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT
Sbjct: 204  LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 263

Query: 301  KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360
            KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ
Sbjct: 264  KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 323

Query: 361  VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420
            VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV
Sbjct: 324  VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 383

Query: 421  KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480
            K       VELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP
Sbjct: 384  K-------VELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 436

Query: 481  LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540
            LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP
Sbjct: 437  LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 496

Query: 541  ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600
            ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE
Sbjct: 497  ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 556

Query: 601  QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660
            QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV
Sbjct: 557  QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 616

Query: 661  LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720
            LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE
Sbjct: 617  LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 676

Query: 721  LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780
            LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK
Sbjct: 677  LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 736

Query: 781  SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840
            SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE
Sbjct: 737  SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 796

Query: 841  AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900
            AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA
Sbjct: 797  AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 856

Query: 901  NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960
            NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK
Sbjct: 857  NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 916

Query: 961  LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020
            LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL
Sbjct: 917  LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 976

Query: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080
            CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK
Sbjct: 977  CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1036

Query: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140
            SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP
Sbjct: 1037 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1096

Query: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200
            FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR
Sbjct: 1097 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1156

Query: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254
            ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI
Sbjct: 1157 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1210


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 33/200 (16%)

Query: 840  EAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGY 899
            E K  I D  KQ  + ++      ++ E+E   +D  L  L   + D   +L+  T L  
Sbjct: 256  EYKKEINDKEKQVSLLLI------QITEKENKMKD--LTFLLEESRDKVNQLEEKTKLQS 307

Query: 900  AN-----GNLVHGSNQKESVFMRLNNRI---KALEVNMSLSGRYLEELSQRYRKQMEEMQ 951
             N         H + + E + + L   +   KALE ++ ++ + + +L++    QMEE  
Sbjct: 308  ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367

Query: 952  KA----------FNKTIVKLQNTSRIAEEQDQRQTEAIQLL-------QAQLTNMTQLVS 994
            KA          F  T+  L+   R  +++ ++  + +++L        ++L  MT+L +
Sbjct: 368  KARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTN 427

Query: 995  NLSATVAELKREVSDRQSYL 1014
            N    + ELK+ + ++++ L
Sbjct: 428  NKEVELEELKKVLGEKETLL 447



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 75/391 (19%), Positives = 158/391 (40%), Gaps = 41/391 (10%)

Query: 610 ESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLVLAQPPLLLP 669
           E ETQ+  S           +E+    CS+   L  ++ R  L K +D L +    L   
Sbjct: 358 EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQR--LEKNEDQLKILTMELQKK 415

Query: 670 AESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTL 729
           +     S L+ ++    N  +E E    VLG+  + ++++       +  EL+ +  + +
Sbjct: 416 S-----SELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE--ELKGTEQELI 468

Query: 730 SQSLLLDITPEINPLP--KIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFS-- 785
              LL     E++ L      ++ S +Y +  +      ++   E++NE  + +E  S  
Sbjct: 469 G--LLQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHC 520

Query: 786 ---SIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAK 842
              S+E   +T ET+ +   + N  +ED+N+ +   K  E ++  I      + +     
Sbjct: 521 NKLSLENKELTQETSDMTLELKNQ-QEDINNNK---KQEERMLKQIENLQETETQ----L 572

Query: 843 MNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANG 902
            N  +  ++ L    D       K EE       LR        +  ELQ         G
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNN---LRKQVENKNKYIEELQQENKALKKKG 629

Query: 903 NLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQ 962
                 +++ +V+     ++  LE+ +  + +   E++  Y+K++E+ + +    + +++
Sbjct: 630 T---AESKQLNVY---EIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVE 683

Query: 963 NTSRIAEEQDQRQTEAIQLLQAQLTNMTQLV 993
               IA+E  + Q E  +  Q ++  M  L+
Sbjct: 684 KAKVIADEAVKLQKEIDKRCQHKIAEMVALM 714



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 81/381 (21%), Positives = 147/381 (38%), Gaps = 61/381 (16%)

Query: 765  IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI--IKEDVNSMQIFTKL-S 821
            + QE   EI+++ +Q S     +    IT + NK+ +L   +   ++ VN ++  TKL S
Sbjct: 253  LEQEYKKEINDKEKQVS-----LLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQS 307

Query: 822  ETIVPPINTA--TVPDNEDGEAKMNIADTAKQTL-----ISVVDSSSLPEVKEEEQSPED 874
            E +   I        + ED +  +  + + ++ L     I+      L E KE +    +
Sbjct: 308  ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367

Query: 875  ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGR 934
                      T+F   + +  +L             ++    +  +++K L + +     
Sbjct: 368  KARAAHSFVVTEFETTVCSLEEL----------LRTEQQRLEKNEDQLKILTMELQKKSS 417

Query: 935  YLEE---LSQRYRKQMEEMQKAFNKTIVKLQNTS---RIAEEQDQRQTEAIQLLQA---- 984
             LEE   L+     ++EE++K   +    L       +IAEE    + E I LLQA    
Sbjct: 418  ELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKE 477

Query: 985  ------QLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQ 1038
                  QLT +T      S  V +LK E+ + +         C  L L       +  +Q
Sbjct: 478  VHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSL-----ENKELTQ 532

Query: 1039 FDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVE 1098
               D   +L    +           D  N K++    L + ++LQ T  ++     Y+ E
Sbjct: 533  ETSDMTLELKNQQE-----------DINNNKKQEERMLKQIENLQETETQLRNELEYVRE 581

Query: 1099 PLKFSPEKKKKRCKYKIEKIE 1119
             LK    +K+   K K++K E
Sbjct: 582  ELK----QKRDEVKCKLDKSE 598


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
           sapiens]
          Length = 1782

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 65/287 (22%), Positives = 118/287 (41%), Gaps = 56/287 (19%)

Query: 50  ENEDVQFQKKDEREGPINAESLGKSGSNLPISPKE--HKLK------------DDSIVDV 95
           E E  +   +++ +  + +E L  S    P  P E  H+ +            ++ +   
Sbjct: 329 EQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGS 388

Query: 96  QNTESKKLSPPVVETLPT-VDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSG 154
           Q    +K +P   E     +++H+E   A V   TVE  +    +E+         E +G
Sbjct: 389 QGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVE--------ETAG 440

Query: 155 TIPI-------AKPSETEQSET------DCDVGEALDASAPIEQPSFV--SPPDSLVGQH 199
           ++P        A+P E E ++        C  GE     A +     V   PP+ +V + 
Sbjct: 441 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE- 499

Query: 200 IENVSSSHG---KGKITKSEFES----KVSASEQ----GGGDPKSALNASDNLKNESSDY 248
           +E +SS      +G   K  F S    K+S  +Q    GGGD +S  +      +  S  
Sbjct: 500 VEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQE 559

Query: 249 TKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNG 295
            + G+   +S +SP++PE+I   +   K + EV+++      A+S+G
Sbjct: 560 EQKGE---SSASSPEEPEEITCLE---KGLAEVQQDGEAEEGATSDG 600


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
           sapiens]
          Length = 1684

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 65/287 (22%), Positives = 118/287 (41%), Gaps = 56/287 (19%)

Query: 50  ENEDVQFQKKDEREGPINAESLGKSGSNLPISPKE--HKLK------------DDSIVDV 95
           E E  +   +++ +  + +E L  S    P  P E  H+ +            ++ +   
Sbjct: 231 EQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGS 290

Query: 96  QNTESKKLSPPVVETLPT-VDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSG 154
           Q    +K +P   E     +++H+E   A V   TVE  +    +E+         E +G
Sbjct: 291 QGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVE--------ETAG 342

Query: 155 TIPI-------AKPSETEQSET------DCDVGEALDASAPIEQPSFV--SPPDSLVGQH 199
           ++P        A+P E E ++        C  GE     A +     V   PP+ +V + 
Sbjct: 343 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE- 401

Query: 200 IENVSSSHG---KGKITKSEFES----KVSASEQ----GGGDPKSALNASDNLKNESSDY 248
           +E +SS      +G   K  F S    K+S  +Q    GGGD +S  +      +  S  
Sbjct: 402 VEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQE 461

Query: 249 TKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNG 295
            + G+   +S +SP++PE+I   +   K + EV+++      A+S+G
Sbjct: 462 EQKGE---SSASSPEEPEEITCLE---KGLAEVQQDGEAEEGATSDG 502


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 56/281 (19%), Positives = 105/281 (37%), Gaps = 4/281 (1%)

Query: 32   SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91
            +SS S++S  S D + + ++ D      D  +   +++S   S S+      +     DS
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 92   IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIE 151
                 +++S   S     +  +       S+   DS    N S SS S  +  S  D   
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSN 1140

Query: 152  KSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK 211
             S +   ++ S++  S    D  ++ D+S   +     +  DS       + S S     
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200

Query: 212  ITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTF 271
             + S   S  S S        S+ ++  +  NESSD +   D   +S +S  D  D    
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS--DSSDSSDS 1258

Query: 272  DEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYAS 312
             +      +    +S+S + ++NG    +     + N+  S
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 62/314 (19%), Positives = 118/314 (37%), Gaps = 24/314 (7%)

Query: 33  SSASASSYYSQD-DNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91
           S +++  Y S D D+ +++ +D     +       N+ES   S S    S    + KD+ 
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 92  IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIE 151
                 ++SK       ++  T D +   SN   ++   +N  S S    +  S  D  +
Sbjct: 503 ----NGSDSKGAEDDDSDS--TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556

Query: 152 KSGTIPIAKPSETEQSET---------DCDVGEALDASAPIEQPSFVSPPDSLVGQHIEN 202
            S +   +  S+++ S++         D D  ++ D+ +     S  S   S      ++
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 203 VSSSHGKGKITKSEFES-----KVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPT 257
             SS  K   +KSE +S     K  +S+    D     ++SD+  N S+        D +
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS-SNSSNSSDSSDSSDSS 675

Query: 258 SVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVECGA 317
             +S  D  +  + D           E S S  +S +  S ++     N ++  S     
Sbjct: 676 DSSSSSDSSN--SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733

Query: 318 KILAANPEAKSTSA 331
              ++N    S S+
Sbjct: 734 SSDSSNSSDSSDSS 747



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 43/231 (18%), Positives = 89/231 (38%), Gaps = 4/231 (1%)

Query: 31  ESSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDD 90
           +SS +S SS  S   N +  N+        +     ++ +   S  +   S  +     D
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825

Query: 91  SIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEI 150
           S     +++S   S     +  +     +SSN    S + ++  SS +S  +  S   + 
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885

Query: 151 EKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKG 210
            +S     +  S    + +D D  ++ ++S   +  +     +S       N S S    
Sbjct: 886 NESSN---SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942

Query: 211 KITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVAS 261
             + S  +S  S+      D  ++ ++SD+  ++SSD +   D   +S +S
Sbjct: 943 DSSDSS-DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 49/271 (18%), Positives = 104/271 (38%), Gaps = 15/271 (5%)

Query: 32  SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91
           S S+S+S   +  D+    +     +  D  +   +  S     SN   S  +     DS
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734

Query: 92  IVDVQNTESKKLSPPVVETLPTVDLHE-----ESSNAVVDSETVENISSSSTSEITPISK 146
             D  N+     S     +  + D  +     +SS++   S++ ++ +SS +++ +  S 
Sbjct: 735 S-DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793

Query: 147 LDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSS 206
             +   S     +  S      +D D   + D+S   +     +  DS      ++  SS
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS-----SDSSDSS 848

Query: 207 HGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPE 266
            G    + +  +S  S+      D  ++ ++SD+  ++S++ +   D   +S +S  D  
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS--SDSNESSNSSDSSDSSNSSDSDSS 906

Query: 267 DIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 297
           D     +          + S+S ++S N  S
Sbjct: 907 DSSNSSD--SSDSSNSSDSSESSNSSDNSNS 935



 Score = 37.4 bits (85), Expect = 0.091
 Identities = 54/271 (19%), Positives = 102/271 (37%), Gaps = 7/271 (2%)

Query: 32  SSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDS 91
           SSS S SS     D+   ++ D      D  +   +++S   S S+   S       D S
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSS-NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634

Query: 92  IVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPIS-KLDEI 150
             D ++  S   S    +   + D    SSN+   S++ ++  SSS+S+ +  S   D  
Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSD-SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693

Query: 151 EKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKG 210
           + S +   +  S++  S++      +   S+  +  +     DS       + S S    
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753

Query: 211 KITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGD----IDPTSVASPKDPE 266
             + S   S  S S        S+ +++ +  N+SS+ +   D     D ++ +   D  
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813

Query: 267 DIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 297
           D    D           + S S ++S +  S
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 49/288 (17%), Positives = 104/288 (36%), Gaps = 11/288 (3%)

Query: 31  ESSSASASSYYSQDDNCALENEDVQFQKKDEREGPINAESLGKS----GSNLPISPKEHK 86
           +S+S+ +S      D+    N        D  +   +++S   S     S+   S +   
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703

Query: 87  LKDDSIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISK 146
             D S  D  ++     S              +SSN+   S++ ++ +SS +S+ +  S 
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 147 L----DEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIEN 202
                D  + S +   +  S++  S    D  ++ ++S            DS       +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 203 VSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLK-NESSDYTKPGDIDPTSVAS 261
             SS+       S       +S+   G    + N SD+   ++SSD +   +   +S +S
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 262 PKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNN 309
             D  +     +        + + S S ++S +  S  +    ++ N+
Sbjct: 884 --DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/292 (19%), Positives = 115/292 (39%), Gaps = 28/292 (9%)

Query: 751  ESVEYEAGHIPSPVIPQESSVEIDNET-EQKSESFSSIEKPSITYETNKVNELMDNIIKE 809
            E +E E   +   +  +   V++  +T  Q  E     E  ++  ETNK+       +++
Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288

Query: 810  DVNSMQIFTKLSETIVPPINTATVPDNE-----DGEAKMNIADTAK-----QTLISVVDS 859
            D+  MQ   +  E  + P+  A    +E       E K+   D  +     Q L+S    
Sbjct: 1289 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKD 1348

Query: 860  SSLPEVKE--EEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHG--------SN 909
                E ++   E+      ++ L        AE+  S      N NL+            
Sbjct: 1349 PDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRT 1408

Query: 910  QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 969
            +KE++   L+ +I  ++  +    + ++++ +RY+ Q EE++   +K +     +S   +
Sbjct: 1409 EKETIQKDLDAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQ 1467

Query: 970  EQD------QRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015
            EQ       Q   E +   + +  ++   V NL  T++E + E  + Q   V
Sbjct: 1468 EQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTV 1519



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 98/503 (19%), Positives = 186/503 (36%), Gaps = 104/503 (20%)

Query: 529  ENATATAAPKMPE-STPVSTPVPSP-----EYVTTEVHTHDMEPSTPDTPKESPIVQLVQ 582
            ++ +  + PK P  S  VSTP P P     E +  +     ++    +  KE    + +Q
Sbjct: 634  DDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQ 693

Query: 583  EEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVA 642
             E+ E     VT L                     S+ T I     F+   Y+     V 
Sbjct: 694  NEQLEKLQEQVTDLR--------------------SQNTKISTQLDFASKRYEMLQDNVE 733

Query: 643  LYRQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSG--------ELENTNIEREA 694
             YR+   +   + +      Q       E +  ++ Q L G        E+   N+++E 
Sbjct: 734  GYRREITSLHERNQKLTATTQ-----KQEQIINTMTQDLRGANEKLAVAEVRAENLKKEK 788

Query: 695  ETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVE 754
            E + L ++  S  ++ L+             ++   Q+LLL     I  +  +E SE+  
Sbjct: 789  EMLKLSEVRLSQQRESLL-------------AEQRGQNLLLTNLQTIQGI--LERSET-- 831

Query: 755  YEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSM 814
                         E+   + ++ E+     S ++K  +  E  + + L  N+   DV  +
Sbjct: 832  -------------ETKQRLSSQIEKLEHEISHLKK-KLENEVEQRHTLTRNL---DVQLL 874

Query: 815  QIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTL----ISVVDSSSLPEVKEEEQ 870
                +L       +NT  +  N    A+  IA T KQ L    + V   SS    K +  
Sbjct: 875  DTKRQLDTETNLHLNTKELLKN----AQKEIA-TLKQHLSNMEVQVASQSSQRTGKGQPS 929

Query: 871  SPED-----ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKAL 925
            + ED     + LR  +    D    L+ ST            SN ++   M     + +L
Sbjct: 930  NKEDVDDLVSQLRQTEEQVNDLKERLKTST------------SNVEQYQAM-----VTSL 972

Query: 926  EVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQ 985
            E +++   +  EE+ +    +++E  +   +   KL    +  +E    +  AI+ ++ Q
Sbjct: 973  EESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQ 1032

Query: 986  LTNMTQLVSNLSATVAELKREVS 1008
            L+ + + +S++   V E  +  S
Sbjct: 1033 LSELKKTLSSVQNEVQEALQRAS 1055


>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
          Length = 1280

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%)

Query: 837  EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 896
            ++G      + +++++ +  V +    + ++ +   + A +  ++RTA       Q   D
Sbjct: 1054 QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 1113

Query: 897  LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 956
            +     NL    + +     +    I  L+  + +S R LEE  +R   Q ++MQK   +
Sbjct: 1114 VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1168

Query: 957  TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014
               +L+++  R+  +Q+++ ++           M  ++S L A   ELK++ ++ Q+ +
Sbjct: 1169 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1216


>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%)

Query: 837  EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 896
            ++G      + +++++ +  V +    + ++ +   + A +  ++RTA       Q   D
Sbjct: 913  QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 972

Query: 897  LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 956
            +     NL    + +     +    I  L+  + +S R LEE  +R   Q ++MQK   +
Sbjct: 973  VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1027

Query: 957  TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014
               +L+++  R+  +Q+++ ++           M  ++S L A   ELK++ ++ Q+ +
Sbjct: 1028 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1075


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 54/199 (27%), Positives = 80/199 (40%), Gaps = 21/199 (10%)

Query: 77  NLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSS 136
           N P   KE+   +++       E+K +SP V E    +D  ++  N          +  S
Sbjct: 757 NSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDF-------RLQPS 809

Query: 137 STSEITP--ISKLDEIEKSGTI------PIAKPSETEQSETDCDVGEALDASAPIEQPSF 188
           STSE     ++K  E EKS  +      P AK S  E S ++C  G +   ++P   PS 
Sbjct: 810 STSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSS-KPNSPSISPSI 868

Query: 189 VSPPDSLVGQHI--ENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESS 246
           +S  +   G  +  + V +S    K  K + E K  A+EQ     KS LN +    N  S
Sbjct: 869 LSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQ---VRKSTLNPNAKEFNPRS 925

Query: 247 DYTKPGDIDPTSVASPKDP 265
                    PTS      P
Sbjct: 926 FSQPKPSTTPTSPRPQAQP 944


>gi|133778961 testis expressed 15 [Homo sapiens]
          Length = 2789

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 52/229 (22%)

Query: 100  SKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITP----ISKLDEIEKSGT 155
            SKK S P +      D   ESS + +D + +  + S + S   P      +  E+ K+  
Sbjct: 1329 SKKYSIPQLSAAAVTDSEGESSKSYLDKQRILTVDSFAASSTVPHCEQSCREKELLKTEQ 1388

Query: 156  IPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
                    T+ +ET+      LD ++  E+       D   G++I  +SSS         
Sbjct: 1389 CSSGNCLHTDGNETNVTENYELDVASGTEE-------DKSYGENIVELSSS--------- 1432

Query: 216  EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWK 275
                             S+L   DN+K  SS+          +    KD ED  T+    
Sbjct: 1433 ----------------DSSLLLKDNVKGSSSE----------TCIVKKDTEDRITW---- 1462

Query: 276  KKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVEC-GAKILAAN 323
             KV + EK K      S   GS    + +  +N  +   C   KI+  N
Sbjct: 1463 -KVKQAEKAKDSVYKRSMTEGSTVNTEYKNQKNQISEESCLNEKIITTN 1510



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 17/159 (10%)

Query: 1102 FSPEKKKKRCKYKIEK----IETIKPEEPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSS 1157
            ++  K KK  + +I K    I +     P   +    I GRK     +D S   E + S 
Sbjct: 903  YNDTKNKKEVESRISKRKLHISSRDQNIPHKDLRRHKIYGRKRRLTSQDSS---ECFSSL 959

Query: 1158 YKGPPSEGSSETSSQSEE---SYFCGISACTSLCNGQSQKTKTEKRA--LKRRRSKVQDQ 1212
                 S+G  +T SQSE+   S    +S   SLC  +    K +K    LK+   +V   
Sbjct: 960  -----SQGRIKTFSQSEKHIKSVLNILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTS 1014

Query: 1213 GKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVS 1251
             +LI  + + + G LP  + II  N   +    G ++VS
Sbjct: 1015 LQLITKVGEERKGPLPKSYAIICNNFWESCDLQGYSSVS 1053


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 118/595 (19%), Positives = 224/595 (37%), Gaps = 77/595 (12%)

Query: 667  LLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMH--QDDLVNHTVDAVELEPS 724
            LL     ++S+L+    +L       E ET VL  L    H  Q+ +   T        S
Sbjct: 531  LLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590

Query: 725  HSQTLSQSLLLDITPEINPLPKIEVSE--SVEYEAGHIPSPVIPQESSV-EIDNETEQKS 781
            H Q  +Q  L D   E     +       S+E     + S +   +  V ++D + + K+
Sbjct: 591  HKQ--AQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKT 648

Query: 782  ESFSSIEKPSITY--------------------ETNKVNELMDNIIKE----DVNSMQIF 817
            E   S E                          E NK+   +D +  +      +  Q+ 
Sbjct: 649  ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE 708

Query: 818  TKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALL 877
            + L E     ++     +  +G+ K   AD+ +   +      +L +++++ Q   D  L
Sbjct: 709  SHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE---VKASKEQALQDLQQQRQLNTDLEL 765

Query: 878  RGLQRTAT-DFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYL 936
            R  + +   +   E+ +ST L     +L   S   ES+  +L  +    E    +  +  
Sbjct: 766  RATELSKQLEMEKEIVSSTRL-----DLQKKSEALESIKQKLTKQ----EEEKQILKQDF 816

Query: 937  EELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNL 996
            E LSQ  + Q EE+      T+ +LQ   ++  E++   TE    L      ++++  +L
Sbjct: 817  ETLSQETKIQHEELNNRIQTTVTELQ---KVKMEKEALMTE----LSTVKDKLSKVSDSL 869

Query: 997  SATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSP 1056
              + +E ++E    ++ ++     C  L   L +Q   NT +   +    L K  +    
Sbjct: 870  KNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ-MENTLKEQKELKKSLEKEKEASHQ 928

Query: 1057 -KRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKI 1115
             K   +S  +  ++ + +      +  QL G          +  LK S E+KKK      
Sbjct: 929  LKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN---------INELKQSSEQKKK------ 973

Query: 1116 EKIETIKPEEPLHPIANGDIKGR-KPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSE 1174
             +IE ++ E  +  +   +++ + +    Q       E    S      E S ET  Q +
Sbjct: 974  -QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032

Query: 1175 ESYFCGISACTSLCNGQSQKTKTEKRALKR-----RRSKVQDQGKLIKTLIQTKS 1224
              ++   S    L   Q  K+  EK +L +      R+++ +Q KLI+ L   K+
Sbjct: 1033 SDFYGRESEL--LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 58/325 (17%), Positives = 125/325 (38%), Gaps = 35/325 (10%)

Query: 720  ELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI-DNETE 778
            EL+ S  Q   Q   L    +I  L K E+   ++ +       +  ++  + +  N  E
Sbjct: 963  ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022

Query: 779  QKSESFSSIEKPSITYETNKVNELMD--------NIIKEDVNSMQIFTKLSETIVPPINT 830
            +  E+F  ++      E+  +    D        ++ +ED+ S +        ++  + T
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKT 1082

Query: 831  ATVPDNEDGEAKMN--------IADTAKQTLIS----VVDSSSLPEVKEEEQSPEDALLR 878
            A     +D   K          + D  K+  +     V + S L E++E +   E  + +
Sbjct: 1083 AKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142

Query: 879  GLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEE 938
              +   +     ++  T+L  A   L+    QK    + L  +  +L+  +    R  + 
Sbjct: 1143 LNEELKSHKLESIKEITNLKDAKQLLIQ---QK----LELQGKADSLKAAVEQEKRNQQI 1195

Query: 939  LSQRYRKQMEEMQKAFNKTIVKLQNT-------SRIAEEQDQRQTEAIQLLQAQLTNMTQ 991
            L  + +K+ EE++K F +   KL +         +  EE + + T  I  L   L  + +
Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255

Query: 992  LVSNLSATVAELKREVSDRQSYLVI 1016
               +    V+EL+++  D +  + +
Sbjct: 1256 EWQSSQRRVSELEKQTDDLRGEIAV 1280



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 49/247 (19%), Positives = 92/247 (37%), Gaps = 34/247 (13%)

Query: 795  ETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLI 854
            E  +V  LMDN+  E     +   KL +      +     +    + +  +A   ++  +
Sbjct: 229  ELVQVQTLMDNMTLERERESE---KLKDECKKLQSQYASSEATISQLRSELAKGPQEVAV 285

Query: 855  SVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESV 914
             V +   L     E       L   L +   D+    +   +   +  N+    +QK+  
Sbjct: 286  YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD 345

Query: 915  FMRLNNRIKALE-------VNMSLSG----RYLEELS----------------QRYRKQM 947
              +L +R+ A E       V +S  G    +  EELS                Q+ R++ 
Sbjct: 346  CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEK 405

Query: 948  E----EMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAEL 1003
            E    ++Q   N+   KL  T R   E   R  E  QL   +L +  Q V++L   ++ L
Sbjct: 406  EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL 465

Query: 1004 KREVSDR 1010
            + ++ ++
Sbjct: 466  EEQLKEK 472


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%)

Query: 866  KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 924
            KEE+    + LL  LQ    +  A LQ+         NL+H +  QKE    +L  ++KA
Sbjct: 251  KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299

Query: 925  LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 974
                 ++    LE       +LSQ   ++ EE+++     N+   +++       + +Q 
Sbjct: 300  TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359

Query: 975  QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014
             + A++ ++ +++++TQ +     T+A  K   SD +  L
Sbjct: 360  YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399


>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
          Length = 495

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%)

Query: 866  KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 924
            KEE+    + LL  LQ    +  A LQ+         NL+H +  QKE    +L  ++KA
Sbjct: 251  KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299

Query: 925  LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 974
                 ++    LE       +LSQ   ++ EE+++     N+   +++       + +Q 
Sbjct: 300  TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359

Query: 975  QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 1014
             + A++ ++ +++++TQ +     T+A  K   SD +  L
Sbjct: 360  YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 7/170 (4%)

Query: 842  KMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 901
            K+ + DT +   +   + SSLP V++E+ S E       + +  D   EL+++   G  +
Sbjct: 612  KVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKS 671

Query: 902  GNLVHGSNQ-KESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960
             + V    Q  +    RL ++I  LE+N   +    E+      K++  + +   +    
Sbjct: 672  LSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKN 731

Query: 961  LQNTS----RIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKRE 1006
              N S     ++EE+DQ  ++  +L  + +T +   V  L   +AE +R+
Sbjct: 732  ADNNSSAFTALSEERDQLLSQVKEL--SMVTELRAQVKQLEMNLAEAERQ 779



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 45/230 (19%), Positives = 93/230 (40%), Gaps = 26/230 (11%)

Query: 795  ETNKVNELMDNIIKEDVNSMQIFTKLSE------TIVPPINTATVPDNEDGEAKMNIADT 848
            E + +N+L++   K   N+   FT LSE      + V  ++  T    +  + +MN+A+ 
Sbjct: 717  EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEA 776

Query: 849  AKQTLISVVDSSSLPEVKEE-------EQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 901
             +Q  +     ++   +  E       E   +D  +  LQ    D   +    + L    
Sbjct: 777  ERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTL---I 833

Query: 902  GNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK- 960
             +L      KES  +    R++ +          +EELSQ   ++  E+ K     + K 
Sbjct: 834  RSLQSQLQNKESEVLEGAERVRHISSK-------VEELSQALSQKELEITKMDQLLLEKK 886

Query: 961  --LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVS 1008
              ++   +  EE+DQ+ TE    +  ++  + +   +L   +  LK +++
Sbjct: 887  RDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 936



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 10/88 (11%)

Query: 934  RYLEELSQ------RYRKQMEEMQKAFNKTI----VKLQNTSRIAEEQDQRQTEAIQLLQ 983
            +Y E+L+Q        +KQ+ E+Q   NK +     KL+   + +EE ++    +   LQ
Sbjct: 2535 QYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2594

Query: 984  AQLTNMTQLVSNLSATVAELKREVSDRQ 1011
             +  ++++ + +L  ++++L R+V+  Q
Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVTALQ 2622



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 33/156 (21%), Positives = 68/156 (43%), Gaps = 8/156 (5%)

Query: 850  KQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN 909
            K+ L+  ++S    ++ E  +  E    + LQ+         +N ++      ++V    
Sbjct: 1583 KEKLVKEIESLKSSKIAESTEWQEKH--KELQKEYEILLQSYENVSNEAERIQHVVEAVR 1640

Query: 910  QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 969
            Q++     L  ++++ E N   + + L+E  Q   +  E+M+K F K+  K Q    + E
Sbjct: 1641 QEKQ---ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK-FAKS--KQQKILELEE 1694

Query: 970  EQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKR 1005
            E D+ + E           M  L+S+ ++   EL+R
Sbjct: 1695 ENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER 1730


>gi|242117996 hypothetical protein LOC392307 [Homo sapiens]
          Length = 402

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 21/137 (15%)

Query: 518 EDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD--MEPSTPDTPKES 575
           EDL E + S S    +T+   +   T  S  VPSP  +  E H+ +   EPS  +TP E+
Sbjct: 28  EDLQENHISESFLKPSTSETPLEPHTSESPLVPSPSQIPLEAHSPETHQEPSISETPSET 87

Query: 576 PI--------VQLVQEEEEEASPST--VTLLGSGE--QEDESS-------PWFESETQIF 616
           P         + +V E+     P +     L S +  +ED SS       PW    T + 
Sbjct: 88  PTYEASLDSPISVVPEKHLTLPPQSRDYVCLSSSDTLKEDLSSESSSNEVPWTRRSTHLS 147

Query: 617 CSELTTICCISSFSEYI 633
            SE     C+S  S  +
Sbjct: 148 ESESLPEHCLSGPSSQV 164


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 74/368 (20%), Positives = 156/368 (42%), Gaps = 35/368 (9%)

Query: 656  KDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNH- 714
            KD +++ +   L   E  ++S    L  ++E+ N E E     L  +  +  Q+  + + 
Sbjct: 982  KDNMLVQRTSNLEHLECENIS----LKEQVESINKELEITKEKLHTIEQAWEQETKLGNE 1037

Query: 715  -TVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI 773
             ++D  +   ++S  +S S  + +  E+  L + + +E  +    H+ + +   E   E 
Sbjct: 1038 SSMDKAKKSITNSDIVSISKKITML-EMKELNERQRAEHCQKMYEHLRTSLKQME---ER 1093

Query: 774  DNETEQKSESFSSIEKPSITYETNKVNELMDNIIK--EDVNSMQIFTKLSETIVPPINTA 831
            + E E K    + I   +   E    +EL D++ K   D +  +I       +   +  +
Sbjct: 1094 NFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVS 1153

Query: 832  TVPDNED-GEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAE 890
             + +  D    ++ I +  +Q+    V+S  +  +  + QS E +L+  L +       +
Sbjct: 1154 KLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSL--Q 1211

Query: 891  LQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNM---SLSGR----YLEELSQRY 943
            L  +T LG    ++     + E+  +RL  ++   E  +    L GR    +L +  Q  
Sbjct: 1212 LSEATALGKLE-SITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSL 1270

Query: 944  RKQME-----EMQKAFNKTIVKLQNTS-RIAEEQDQRQTEAIQL------LQAQLTNMTQ 991
            R+Q         Q+ F+KT+++LQN   +I +E    Q E   +      ++ +L  + +
Sbjct: 1271 RRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEE 1330

Query: 992  LVSNLSAT 999
            L+S L  T
Sbjct: 1331 LISTLKDT 1338


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
            sapiens]
          Length = 1133

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%)

Query: 776  ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835
            +TE K ++ SS     +  E NKV  + + +I+E   +++  T + E +      +   +
Sbjct: 513  KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563

Query: 836  NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895
             +D + K+   +     L+S V+      ++  E   +D L   L + +       +++T
Sbjct: 564  RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616

Query: 896  DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955
             L   N  +   S + E + ++L + +KA+E ++  +    E L +RY  + ++ Q   +
Sbjct: 617  ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674

Query: 956  KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015
            K +  ++      +  ++ +T   Q L  +L        +LS  V  LK ++ +   Y+ 
Sbjct: 675  KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731

Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070
               ++C + G    L   + +  N ++  G  I  L K  +     R FS     +L  R
Sbjct: 732  TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788

Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101
            R S P + SK +Q    + +P D   + PL+
Sbjct: 789  RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819


>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
            sapiens]
          Length = 893

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%)

Query: 776  ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835
            +TE K ++ SS     +  E NKV  + + +I+E   +++  T + E +      +   +
Sbjct: 273  KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 323

Query: 836  NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895
             +D + K+   +     L+S V+      ++  E   +D L   L + +       +++T
Sbjct: 324  RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 376

Query: 896  DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955
             L   N  +   S + E + ++L + +KA+E ++  +    E L +RY  + ++ Q   +
Sbjct: 377  ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 434

Query: 956  KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015
            K +  ++      +  ++ +T   Q L  +L        +LS  V  LK ++ +   Y+ 
Sbjct: 435  KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 491

Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070
               ++C + G    L   + +  N ++  G  I  L K  +     R FS     +L  R
Sbjct: 492  TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 548

Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101
            R S P + SK +Q    + +P D   + PL+
Sbjct: 549  RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 579


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
            sapiens]
          Length = 1135

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%)

Query: 776  ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 835
            +TE K ++ SS     +  E NKV  + + +I+E   +++  T + E +      +   +
Sbjct: 513  KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563

Query: 836  NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 895
             +D + K+   +     L+S V+      ++  E   +D L   L + +       +++T
Sbjct: 564  RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616

Query: 896  DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 955
             L   N  +   S + E + ++L + +KA+E ++  +    E L +RY  + ++ Q   +
Sbjct: 617  ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674

Query: 956  KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 1015
            K +  ++      +  ++ +T   Q L  +L        +LS  V  LK ++ +   Y+ 
Sbjct: 675  KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731

Query: 1016 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1070
               ++C + G    L   + +  N ++  G  I  L K  +     R FS     +L  R
Sbjct: 732  TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788

Query: 1071 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1101
            R S P + SK +Q    + +P D   + PL+
Sbjct: 789  RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 182 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 240

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 350

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 351 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 404

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 405 KEKAKEEDREK 415



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 403 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 462

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 463 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 522

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 523 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 582

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 583 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 636

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 637 KAKDSAKTTEETSKPK 652


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 201 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 259

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 260 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 319

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 320 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 369

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 370 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 423

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 424 KEKAKEEDREK 434



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 422 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 481

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 482 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 541

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 542 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 601

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 602 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 655

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 656 KAKDSAKTTEETSKPK 671


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 195 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 253

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 254 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 313

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 314 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 363

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 364 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 417

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 418 KEKAKEEDREK 428



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 416 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 475

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 476 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 535

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 536 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 595

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 596 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 649

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 650 KAKDSAKTTEETSKPK 665


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 236 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 294

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 295 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 354

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 355 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 404

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 405 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 458

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 459 KEKAKEEDREK 469



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 457 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 516

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 517 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 576

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 577 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 636

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 637 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 690

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 691 KAKDSAKTTEETSKPK 706


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 297 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 355

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 356 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 415

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 416 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 465

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 466 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 519

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 520 KEKAKEEDREK 530



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 518 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 577

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 578 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 637

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 638 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 697

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 698 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 751

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 752 KAKDSAKTTEETSKPK 767


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 300 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 358

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 359 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 418

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 419 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 468

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 469 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 522

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 523 KEKAKEEDREK 533



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 521 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 580

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 581 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 640

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 641 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 700

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 701 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 754

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 755 KAKDSAKTTEETSKPK 770


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 278 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 336

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 337 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 396

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 397 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 446

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 447 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 500

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 501 KEKAKEEDREK 511



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 499 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 558

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 559 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 618

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 619 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 678

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 679 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 732

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 733 KAKDSAKTTEETSKPK 748


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 284 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 342

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 343 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 402

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 403 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 452

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 453 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 506

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 507 KEKAKEEDREK 517



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 505 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 564

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 565 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 624

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 625 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 684

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 685 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 738

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 739 KAKDSAKTTEETSKPK 754


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 214 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 272

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 273 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 332

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 333 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 382

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 383 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 436

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 437 KEKAKEEDREK 447



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 435 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 494

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 495 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 554

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 555 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 614

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 615 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 668

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 669 KAKDSAKTTEETSKPK 684


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 42  SQDDNCALENEDVQFQKKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK 101
           S D  C       +  +K+E    + A+S G   S  P   K+ K++ D++ D Q  E+ 
Sbjct: 319 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD-QALEAL 377

Query: 102 KLSPPVVETLPTVDLH--EESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTI--- 156
             S    +  P +DL   +E   A    E +E       +  +        +K G     
Sbjct: 378 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 437

Query: 157 -PIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 215
            P  KP    +SE   ++ E  D S   E+PS          +  E    S        S
Sbjct: 438 EPEEKPKPRSESELIDELSEDFDRSECKEKPS----------KPTEKTEESKAAAPAPVS 487

Query: 216 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPED-IPTFDEW 274
           E   + S        P+ A      LK    D       D        DPED  P  D+ 
Sbjct: 488 EAVCRTSMCSIQSAPPEPA-----TLKGTVPDDAVEALADSLG-KKEADPEDGKPVMDKV 541

Query: 275 KKKVMEVEKEK 285
           K+K  E ++EK
Sbjct: 542 KEKAKEEDREK 552



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 54/256 (21%), Positives = 94/256 (36%), Gaps = 34/256 (13%)

Query: 58  KKDEREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLH 117
           K  E+    + E LG+    +P   +  ++KD     +   ESK+  PP+ E      L 
Sbjct: 540 KVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALS 599

Query: 118 EESSN--------------AVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE 163
           E+ S               A   SE V    +S+T    P     + +K     + K S+
Sbjct: 600 EDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 659

Query: 164 T-EQSETDCDVGEALD----ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGK----ITK 214
           +  Q + D D  + ++      A  E    +   D  +     ++   +G+ K     TK
Sbjct: 660 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 719

Query: 215 SEFESKVSASEQG-----GGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIP 269
              +SK  A +Q       GD  S  + ++  +N + D  K       + +S K P++  
Sbjct: 720 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK------KAASSSKAPKNGG 773

Query: 270 TFDEWKKKVMEVEKEK 285
              +  K   E  K K
Sbjct: 774 KAKDSAKTTEETSKPK 789


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,272,532
Number of Sequences: 37866
Number of extensions: 2231234
Number of successful extensions: 10009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 296
Number of HSP's that attempted gapping in prelim test: 9279
Number of HSP's gapped (non-prelim): 1053
length of query: 1254
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1140
effective length of database: 13,930,794
effective search space: 15881105160
effective search space used: 15881105160
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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