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Search of human proteins with 71361688
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71361688 myeloblastin [Homo sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71361688 myeloblastin [Homo sapiens] 528 e-150
gi|4503549 neutrophil elastase preproprotein [Homo sapiens] 271 3e-73
gi|11342670 azurocidin 1 preproprotein [Homo sapiens] 192 3e-49
gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens] 162 3e-40
gi|4503149 cathepsin G preproprotein [Homo sapiens] 159 2e-39
gi|221625528 granzyme B precursor [Homo sapiens] 158 4e-39
gi|15529990 granzyme H [Homo sapiens] 150 1e-36
gi|42544239 complement factor D preproprotein [Homo sapiens] 143 1e-34
gi|47551347 protease, serine-like 1 [Homo sapiens] 142 3e-34
gi|4885369 granzyme M precursor [Homo sapiens] 136 2e-32
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 135 3e-32
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 135 5e-32
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 132 3e-31
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 130 1e-30
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 129 2e-30
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 129 3e-30
gi|5453676 granzyme A precursor [Homo sapiens] 127 1e-29
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 126 2e-29
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 126 2e-29
gi|4505881 plasminogen [Homo sapiens] 125 4e-29
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 125 5e-29
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] 123 1e-28
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 123 2e-28
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 122 2e-28
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 122 2e-28
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 122 2e-28
gi|4504235 granzyme K precursor [Homo sapiens] 122 4e-28
gi|58218970 protease, serine, 36 [Homo sapiens] 121 5e-28
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 121 7e-28
gi|15559207 elastase 2A preproprotein [Homo sapiens] 119 2e-27
>gi|71361688 myeloblastin [Homo sapiens]
Length = 256
Score = 528 bits (1360), Expect = e-150
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL 60
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
Sbjct: 1 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL 60
Query: 61 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL 120
IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
Sbjct: 61 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL 120
Query: 121 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF 180
LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
Sbjct: 121 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF 180
Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240
FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
Sbjct: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV 240
Query: 241 DWIRSTLRRVEAKGRP 256
DWIRSTLRRVEAKGRP
Sbjct: 241 DWIRSTLRRVEAKGRP 256
>gi|4503549 neutrophil elastase preproprotein [Homo sapiens]
Length = 267
Score = 271 bits (694), Expect = 3e-73
Identities = 134/242 (55%), Positives = 176/242 (72%), Gaps = 3/242 (1%)
Query: 10 LASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTA 69
LA VL ALLL G A A+EIVGG A+PH+ P+M SLQ+RG HFCG TLI P+FV++A
Sbjct: 12 LACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSA 68
Query: 70 AHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPAN 129
AHC+ ++ R V VVLGAHN+ +EPT+Q F+V ++F N YD N LND++++QL+ A
Sbjct: 69 AHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSAT 128
Query: 130 LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICT 189
++A+V QLP Q + + +G QCLAMGWG +G + A VLQELNVTVVT CR N+CT
Sbjct: 129 INANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCT 188
Query: 190 FVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRR 249
V R+AG+CFGDSG PL+C+G+I GI SFV GCA+ L+PD F VA +V+WI S ++R
Sbjct: 189 LVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248
Query: 250 VE 251
E
Sbjct: 249 SE 250
>gi|11342670 azurocidin 1 preproprotein [Homo sapiens]
Length = 251
Score = 192 bits (487), Expect = 3e-49
Identities = 105/241 (43%), Positives = 150/241 (62%), Gaps = 7/241 (2%)
Query: 9 ALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
AL + LLA +G++ +IVGG +A+P P++AS+Q N G HFCGG LIH FV+T
Sbjct: 8 ALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMT 64
Query: 69 AAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSP 127
AA C + + VVLGA+++R +E ++Q FS++ + N YD + LND++L+QL
Sbjct: 65 AASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDRE 124
Query: 128 ANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHN 186
ANL++SV + LP Q+ V GT+C GWG + ++ + +NVTV CRP+N
Sbjct: 125 ANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN 184
Query: 187 ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246
+CT V R+ GIC GD G PL+C+G+ G+ SF + C PDFFTRVAL+ DWI
Sbjct: 185 VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGV 242
Query: 247 L 247
L
Sbjct: 243 L 243
>gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens]
Length = 247
Score = 162 bits (410), Expect = 3e-40
Identities = 99/245 (40%), Positives = 133/245 (54%), Gaps = 17/245 (6%)
Query: 14 LLALLLSGAARAAEIVGGHEAQPHSRPYMASLQM-RGNPGSHFCGGTLIHPSFVLTAAHC 72
LL LL A A EI+GG E +PHSRPYMA L++ N S FCGG LI +FVLTAAHC
Sbjct: 8 LLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC 67
Query: 73 LRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131
R + V LGAHN+ +E T Q V + F + Y+ +D++L++L A+L+
Sbjct: 68 AG----RSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLT 123
Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT------FFCRPH 185
+V T+ P Q VP G C GWGR G P + LQE+ + ++ F H
Sbjct: 124 LAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDH 183
Query: 186 N--ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWI 243
N +C PR+ GDSGGPL+C G+ QGI V +G + P FTR++ Y WI
Sbjct: 184 NLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGI---VSYGRSDAKPPAVFTRISHYRPWI 240
Query: 244 RSTLR 248
L+
Sbjct: 241 NQILQ 245
>gi|4503149 cathepsin G preproprotein [Homo sapiens]
Length = 255
Score = 159 bits (402), Expect = 2e-39
Identities = 94/246 (38%), Positives = 135/246 (54%), Gaps = 18/246 (7%)
Query: 13 VLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC 72
+LLA LL A A EI+GG E++PHSRPYMA LQ++ G CGG L+ FVLTAAHC
Sbjct: 6 LLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHC 65
Query: 73 LRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131
+NV LGAHN++ +E TQQH + + + Y+ ND++L+QLS +
Sbjct: 66 WGS----NINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRN 121
Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV---------VTFFC 182
+V V LP+ + + GT C GWGRV L+E+ + V +
Sbjct: 122 RNVNPVALPRAQEGLRPGTLCTVAGWGRVSMR-RGTDTLREVQLRVQRDRQCLRIFGSYD 180
Query: 183 RPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242
IC R + GDSGGPL+C+ + GI V +G ++ + P+ FTRV+ ++ W
Sbjct: 181 PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGI---VSYGKSSGVPPEVFTRVSSFLPW 237
Query: 243 IRSTLR 248
IR+T+R
Sbjct: 238 IRTTMR 243
>gi|221625528 granzyme B precursor [Homo sapiens]
Length = 247
Score = 158 bits (400), Expect = 4e-39
Identities = 96/248 (38%), Positives = 132/248 (53%), Gaps = 18/248 (7%)
Query: 13 VLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC 72
+LLA LL A A EI+GGHEA+PHSRPYMA L + CGG LI FVLTAAHC
Sbjct: 6 LLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC 65
Query: 73 LRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131
+NV LGAHN++ QEPTQQ V + + Y+ +N ND++L+QL A +
Sbjct: 66 WGS----SINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRT 121
Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FF 181
+V ++LP V G C GWG+ + LQE+ +TV ++
Sbjct: 122 RAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYY 181
Query: 182 CRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241
+C P K GDSGGPL+C+ + QGI V +G + P T+V+ +V
Sbjct: 182 DSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGI---VSYGRNNGMPPRACTKVSSFVH 238
Query: 242 WIRSTLRR 249
WI+ T++R
Sbjct: 239 WIKKTMKR 246
>gi|15529990 granzyme H [Homo sapiens]
Length = 246
Score = 150 bits (379), Expect = 1e-36
Identities = 94/249 (37%), Positives = 132/249 (53%), Gaps = 19/249 (7%)
Query: 13 VLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC 72
+LLA LL+ A EI+GGHEA+PHSRPYMA +Q CGG L+ FVLTAAHC
Sbjct: 6 LLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC 65
Query: 73 LRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLS 131
+NV LGAHN++ QE TQQ V + + Y+ +N ND++L+QL A +
Sbjct: 66 ----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWT 121
Query: 132 ASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FF 181
+V ++LP V G C GWG V + A LQE+ +TV +
Sbjct: 122 TAVRPLRLPSSKAQVKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNY 180
Query: 182 CRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 241
R IC P++ GDSGGPL+C + QGI S+ G P + +V+ ++
Sbjct: 181 SRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSY---GNKKGTPPGVYIKVSHFLP 237
Query: 242 WIRSTLRRV 250
WI+ T++R+
Sbjct: 238 WIKRTMKRL 246
>gi|42544239 complement factor D preproprotein [Homo sapiens]
Length = 253
Score = 143 bits (361), Expect = 1e-34
Identities = 93/251 (37%), Positives = 134/251 (53%), Gaps = 22/251 (8%)
Query: 14 LLALLLSGAARAA-----EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
L L+L GAA A I+GG EA+ H+RPYMAS+Q+ G+H CGG L+ +VL+
Sbjct: 7 LAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLN---GAHLCGGVLVAEQWVLS 63
Query: 69 AAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKL-NDVLLIQLSSP 127
AAHCL D V V+LGAH++ EP+++ + V + + + + +D+LL+QLS
Sbjct: 64 AAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEK 123
Query: 128 ANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV---TFFCRP 184
A L +V + + D+ V GT C GWG V LQ + + V+ T R
Sbjct: 124 ATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRT 183
Query: 185 HN--------ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRV 236
H+ +C RR + C GDSGGPL+C G+++G+ + C R P +TRV
Sbjct: 184 HHDGAITERLMCAESNRRDS--CKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRV 241
Query: 237 ALYVDWIRSTL 247
A Y WI S L
Sbjct: 242 ASYAAWIDSVL 252
>gi|47551347 protease, serine-like 1 [Homo sapiens]
Length = 283
Score = 142 bits (358), Expect = 3e-34
Identities = 91/265 (34%), Positives = 136/265 (51%), Gaps = 15/265 (5%)
Query: 4 RPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHP 63
RP +++L + + A+I+GGHE PHSRPYMAS++ G H CGG L+
Sbjct: 10 RPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRA 66
Query: 64 SFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLI 122
+V++AAHC R VVLGAH + T EPTQQ F + + + +Y ND+ L+
Sbjct: 67 RWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLL 126
Query: 123 QLSSPANLSASVATVQLP-QQDQPVPHGTQCLAMGWGRVGAHD--PPAQV---LQELNVT 176
+L+ A L +V ++LP ++ +P GT+C GWG V + PP + ++ L+
Sbjct: 127 RLNGSAVLGPAVGLLRLPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPD 186
Query: 177 VVTFFCRPHNICTFVPRR-----KAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPD 231
V + H T + R + G C DSGGPL+C G+ SF C PD
Sbjct: 187 VCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPD 246
Query: 232 FFTRVALYVDWIRSTLRRVEAKGRP 256
+T+V+ +V WI +RR + P
Sbjct: 247 VYTQVSAFVAWIWDVVRRSSPQPGP 271
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 136 bits (342), Expect = 2e-32
Identities = 92/254 (36%), Positives = 123/254 (48%), Gaps = 18/254 (7%)
Query: 9 ALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
+L + L L G++ +I+GG E PHSRPYMASLQ G SH CGG L+HP +VLT
Sbjct: 7 SLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNG---SHLCGGVLVHPKWVLT 63
Query: 69 AAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPA 128
AAHCL +L +VLG H + + T H A ND+ L+QL
Sbjct: 64 AAHCLAQRMAQL-RLVLGLHTLDSPGLT-FHIKAAIQHPRYKPVPALENDLALLQLDGKV 121
Query: 129 NLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR---- 183
S ++ + LP + Q V GT+C GWG ++VL+EL++ V+ T C
Sbjct: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRF 181
Query: 184 ------PHNICTFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWGCATRLFPDFFTR 235
P +C + C GDSGGPL+C ++ G+ SF C P T
Sbjct: 182 WNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATA 241
Query: 236 VALYVDWIRSTLRR 249
VA YV WIR R
Sbjct: 242 VAPYVSWIRKVTGR 255
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 135 bits (341), Expect = 3e-32
Identities = 96/254 (37%), Positives = 137/254 (53%), Gaps = 36/254 (14%)
Query: 15 LALLLSGAARAA------EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
L L GAA A +IVGG+ + +S PY SL N GSHFCGG+LI +V++
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVS 60
Query: 69 AAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSP 127
AAHC + + V LG HN++ E +Q + A++ + Y+ + ND++LI+LSSP
Sbjct: 61 AAHCYK----TRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSP 116
Query: 128 ANLSASVATVQLPQQDQPVPHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVVT-FFCR 183
A ++A V+T+ LP P GT+CL GWG GA P L+ L+ V+T C+
Sbjct: 117 AVINARVSTISLP--TAPPAAGTECLISGWGNTLSFGADYP--DELKCLDAPVLTQAECK 172
Query: 184 ---PHNI-----CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFF 233
P I C C DSGGP++C+G +QG+ V W GCA + P +
Sbjct: 173 ASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGV---VSWGHGCAWKNRPGVY 229
Query: 234 TRVALYVDWIRSTL 247
T+V YVDWI+ T+
Sbjct: 230 TKVYNYVDWIKDTI 243
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 135 bits (339), Expect = 5e-32
Identities = 90/236 (38%), Positives = 131/236 (55%), Gaps = 30/236 (12%)
Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 86
+IVGG+ + +S PY SL N GSHFCGG+LI +V++AAHC + + V LG
Sbjct: 80 KIVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCYK----TRIQVRLG 131
Query: 87 AHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQP 145
HN++ E +Q + A++ + Y+ + ND++LI+LSSPA ++A V+T+ LP P
Sbjct: 132 EHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP--TAP 189
Query: 146 VPHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVVT-FFCR---PHNI-----CTFVPR 193
GT+CL GWG GA P L+ L+ V+T C+ P I C
Sbjct: 190 PAAGTECLISGWGNTLSFGADYP--DELKCLDAPVLTQAECKASYPGKITNSMFCVGFLE 247
Query: 194 RKAGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFFTRVALYVDWIRSTL 247
C DSGGP++C+G +QG+ V W GCA + P +T+V YVDWI+ T+
Sbjct: 248 GGKDSCQRDSGGPVVCNGQLQGV---VSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 300
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 132 bits (332), Expect = 3e-31
Identities = 91/254 (35%), Positives = 134/254 (52%), Gaps = 34/254 (13%)
Query: 14 LLALLLSGAARAA------EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVL 67
LL L AA AA +IVGG+ + +S PY SL N G HFCGG+LI+ +V+
Sbjct: 4 LLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVV 59
Query: 68 TAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSS 126
+A HC + + V LG HN+ E +Q + A++ + YD + ND++LI+LSS
Sbjct: 60 SAGHCYKS----RIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSS 115
Query: 127 PANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAH--DPPAQVLQELNVTVVTFF--- 181
A ++A V+T+ LP P GT+CL GWG + D P + LQ L+ V++
Sbjct: 116 RAVINARVSTISLP--TAPPATGTKCLISGWGNTASSGADYPDE-LQCLDAPVLSQAKCE 172
Query: 182 ------CRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIW--GCATRLFPDFF 233
+ C C GDSGGP++C+G +QG+ V W GCA + P +
Sbjct: 173 ASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGV---VSWGDGCAQKNKPGVY 229
Query: 234 TRVALYVDWIRSTL 247
T+V YV WI++T+
Sbjct: 230 TKVYNYVKWIKNTI 243
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 130 bits (327), Expect = 1e-30
Identities = 88/265 (33%), Positives = 129/265 (48%), Gaps = 32/265 (12%)
Query: 5 PPSPALASVLLALLLSGAARAA------EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG 58
P +P + +L AL + A +I+GGH S+P+ A+L + G CGG
Sbjct: 12 PSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAAL-LAGPRRRFLCGG 70
Query: 59 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVA-QVFLNNYDAENKLN 117
L+ +V+TAAHC R I Q V LG HN+R E TQQ V QV NY++ N
Sbjct: 71 ALLSGQWVITAAHCGRPILQ----VALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDN 126
Query: 118 DVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGA--------------H 163
D++L+QL PA + +V +++ Q GT C GWG + + +
Sbjct: 127 DLMLLQLQQPARIGRAVRPIEVTQAC--ASPGTSCRVSGWGTISSPIARYPASLQCVNIN 184
Query: 164 DPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWG 223
P +V Q+ +T P +C VP+ C GDSGGPL+C G +QG+ S+ +
Sbjct: 185 ISPDEVCQKAYPRTIT----PGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMER 240
Query: 224 CATRLFPDFFTRVALYVDWIRSTLR 248
CA +P +T + Y WI T+R
Sbjct: 241 CALPGYPGVYTNLCKYRSWIEETMR 265
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 129 bits (324), Expect = 2e-30
Identities = 82/248 (33%), Positives = 125/248 (50%), Gaps = 39/248 (15%)
Query: 26 AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVL 85
+ IVGG E + HS+P+ + RG CGG L+HP +VLTAAHC+R+ ++L
Sbjct: 23 SRIVGGWECEKHSQPWQVLVASRGRA---VCGGVLVHPQWVLTAAHCIRNKSV----ILL 75
Query: 86 GAHNVRTQEPTQQHFSVAQVFLNN-YD-----------AENKLNDVLLIQLSSPANLSAS 133
G H++ E T Q F V+ F + YD ++ +D++L++LS PA L+ +
Sbjct: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135
Query: 134 VATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPR 193
V + LP Q+ + GT C A GWG + P + L + V +++C V
Sbjct: 136 VKVMDLPTQEPAL--GTTCYASGWGSI----EPEEFLTPKKLQCVDLHVISNDVCAQVHP 189
Query: 194 RKA--------------GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALY 239
+K C GDSGGPL+C+G++QGI S+ CA P +T+V Y
Sbjct: 190 QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHY 249
Query: 240 VDWIRSTL 247
WI+ T+
Sbjct: 250 RKWIKDTI 257
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 129 bits (323), Expect = 3e-30
Identities = 89/263 (33%), Positives = 135/263 (51%), Gaps = 33/263 (12%)
Query: 10 LASVLLALLLSGAARAAE-IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
L L LL S AA+ + ++ G E PHS+P+ +L RG CG +LI P +VL+
Sbjct: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFN---CGASLISPHWVLS 59
Query: 69 AAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSP 127
AAHC R + V LG HN+R ++ +Q + ++V + Y+A + ND++L++L P
Sbjct: 60 AAHC----QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115
Query: 128 ANLSASVATVQLPQQDQPVPH-GTQCLAMGWGRVGAHDPPA-----------QVLQELNV 175
A L+ V LP + PH G C+ GWG V ++P L N+
Sbjct: 116 ARLNPQVRPAVLPTR---CPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANI 172
Query: 176 TVVT-------FFCRPHN--ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCAT 226
++++ + R N +C R A C GDSGGPL+C GI+QGI S+ C
Sbjct: 173 SIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDN 232
Query: 227 RLFPDFFTRVALYVDWIRSTLRR 249
P +T+V Y++WIR T++R
Sbjct: 233 TTKPGVYTKVCHYLEWIRETMKR 255
>gi|5453676 granzyme A precursor [Homo sapiens]
Length = 262
Score = 127 bits (318), Expect = 1e-29
Identities = 83/253 (32%), Positives = 128/253 (50%), Gaps = 22/253 (8%)
Query: 12 SVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAH 71
SV+++LLL +I+GG+E PHSRPYM L + C G LI +VLTAAH
Sbjct: 13 SVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAH 69
Query: 72 CLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDVLLIQLSSPANL 130
C + + V+LGAH++ +EPT+Q V + F YD + D+ L+QL+ A +
Sbjct: 70 CNLN---KRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKI 126
Query: 131 SASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHNICT 189
+ V + LP++ V GT C GWGR + L+E+N+T++ C N
Sbjct: 127 NKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYN 186
Query: 190 FVP------------RRKAGICFGDSGGPLICDGIIQGIDSFVIWG-CATRLFPDFFTRV 236
F P R C GDSG PL+C+G+ +G+ SF + C P + +
Sbjct: 187 FNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILL 246
Query: 237 A-LYVDWIRSTLR 248
+ +++WI T++
Sbjct: 247 SKKHLNWIIMTIK 259
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 126 bits (316), Expect = 2e-29
Identities = 84/227 (37%), Positives = 113/227 (49%), Gaps = 14/227 (6%)
Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86
IVGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL+ + V+LG
Sbjct: 1820 IVGGCVAHPHSWPWQVSLRTRF--GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 1877
Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146
AH E Q V+++FL A D+ L++LS PA ++ V LP D V
Sbjct: 1878 AHQEVNLESHVQEIEVSRLFLEPTQA-----DIALLKLSRPAVITDKVMPACLPSPDYMV 1932
Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHN-ICTFVPRRKAGICFGDSGG 205
T+C GWG + + + + C + IC R C GDSGG
Sbjct: 1933 TARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLARGTDSCQGDSGG 1992
Query: 206 PLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248
PL+C I+QG+ S+ + GCA P + RV+ +V WI +R
Sbjct: 1993 PLVCFEKDKYILQGVTSWGL-GCARPNKPGVYARVSRFVTWIEGMMR 2038
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 126 bits (316), Expect = 2e-29
Identities = 91/255 (35%), Positives = 134/255 (52%), Gaps = 32/255 (12%)
Query: 12 SVLLALLLSGAARAA------EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSF 65
++LL L AA AA +IVGG+ + +S PY SL N G HFCGG+LI +
Sbjct: 2 NLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL----NSGYHFCGGSLISEQW 57
Query: 66 VLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQL 124
V++A HC + + V LG HN+ E +Q + A++ + Y++ ND+LLI+L
Sbjct: 58 VVSAGHCYKS----RIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKL 113
Query: 125 SSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRV---GAHDPPAQVLQELNVTVVT-F 180
SSPA +++ V+ + LP P GT+ L GWG GA P LQ L+ V++
Sbjct: 114 SSPAVINSRVSAISLP--TAPPAAGTESLISGWGNTLSSGADYP--DELQCLDAPVLSQA 169
Query: 181 FCRP--------HNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDF 232
C + C C GDSGGP++ +G +QGI S+ +GCA + P
Sbjct: 170 ECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGV 228
Query: 233 FTRVALYVDWIRSTL 247
+T+V YVDWI+ T+
Sbjct: 229 YTKVYNYVDWIKDTI 243
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 125 bits (314), Expect = 4e-29
Identities = 87/237 (36%), Positives = 118/237 (49%), Gaps = 25/237 (10%)
Query: 28 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ-RLVNVVLG 86
+VGG A PHS P+ SL+ R G HFCGGTLI P +VLTAAHCL P+ V+LG
Sbjct: 581 VVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 638
Query: 87 AHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPV 146
AH EP Q V+++FL E D+ L++LSSPA ++ V LP + V
Sbjct: 639 AHQEVNLEPHVQEIEVSRLFL-----EPTRKDIALLKLSSPAVITDKVIPACLPSPNYVV 693
Query: 147 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPH----------NICTFVPRRK 195
T+C GWG A +L+E + V+ C + +C
Sbjct: 694 ADRTECFITGWGETQG-TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 752
Query: 196 AGICFGDSGGPLIC----DGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 248
C GDSGGPL+C I+QG+ S+ + GCA P + RV+ +V WI +R
Sbjct: 753 TDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 808
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 125 bits (313), Expect = 5e-29
Identities = 89/264 (33%), Positives = 135/264 (51%), Gaps = 41/264 (15%)
Query: 12 SVLLALLLSGAARAAE--IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTA 69
S+ L++ +GA + IVGG E + HS+P+ ++ G +H CGG L+HP +VLTA
Sbjct: 7 SIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHG--WAH-CGGVLVHPQWVLTA 63
Query: 70 AHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVF---LNNYDA---------ENKLN 117
AHCL+ Q V LG HN+ E T Q V+ F L N E+ +
Sbjct: 64 AHCLKKNSQ----VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH 119
Query: 118 DVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV 177
D++L++LS PA ++ V + LP Q+ + GT C A GWG + P + L+ ++
Sbjct: 120 DLMLLRLSEPAKITDVVKVLGLPTQEPAL--GTTCYASGWGSI----EPEEFLRPRSLQC 173
Query: 178 VTFFCRPHNICTFVPRRK-------AGI-------CFGDSGGPLICDGIIQGIDSFVIWG 223
V+ +++C K AG+ C GDSGGPL+C+G++QGI S+
Sbjct: 174 VSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEP 233
Query: 224 CATRLFPDFFTRVALYVDWIRSTL 247
CA P +T+V Y WI+ T+
Sbjct: 234 CALPEKPAVYTKVVHYRKWIKDTI 257
>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 123 bits (309), Expect = 1e-28
Identities = 94/267 (35%), Positives = 133/267 (49%), Gaps = 34/267 (12%)
Query: 10 LASVLLALLLSG-----AARAAEIVGGHEAQPHSRPYMASLQMRGNPGS--HFCGGTLIH 62
L+S+LL + SG + ++ +V G +A P+S P+ SLQ + GS H CGG+LI
Sbjct: 6 LSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKS-GSFYHTCGGSLIA 64
Query: 63 PSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKL-----N 117
P +V+TA HC+ R VVLG ++ +E +Q + L + N+ N
Sbjct: 65 PDWVVTAGHCISS--SRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGN 122
Query: 118 DVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV 177
D+ LI+LS A L +V LP +P+ T C GWGR+ + P LQE + V
Sbjct: 123 DIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPV 182
Query: 178 VTF-FCRPHN----------ICTFVPRRKAGICFGDSGGPLIC---DG--IIQGIDSFV- 220
V + C N +C R C GDSGGPL C DG + G+ SFV
Sbjct: 183 VDYEHCSRWNWWGSSVKKTMVCAGGDIRSG--CNGDSGGPLNCPTEDGGWQVHGVTSFVS 240
Query: 221 IWGCATRLFPDFFTRVALYVDWIRSTL 247
+GC TR P FTRV+ ++DWI T+
Sbjct: 241 AFGCNTRRKPTVFTRVSAFIDWIEETI 267
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 123 bits (308), Expect = 2e-28
Identities = 88/266 (33%), Positives = 127/266 (47%), Gaps = 37/266 (13%)
Query: 6 PSPALASVLLALLLSGAARAA-------EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG 58
P P A + LLL G A A +++GGHE QPHS+P+ A+L +G CGG
Sbjct: 4 PRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAAL-FQGQ--QLLCGG 60
Query: 59 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVF----LNNYDAEN 114
L+ ++VLTAAHC + P+ V LG H+++ ++ +Q V Q N+ D E+
Sbjct: 61 VLVGGNWVLTAAHCKK--PKYTVR--LGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVED 116
Query: 115 KLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELN 174
+D++L+QL A+L + V + L D G +C GWG V + P LN
Sbjct: 117 HNHDLMLLQLRDQASLGSKVKPISLA--DHCTQPGQKCTVSGWGTVTS--PRENFPDTLN 172
Query: 175 VTVVTFFCRPHNICTFV-------------PRRKAGICFGDSGGPLICDGIIQGIDSFVI 221
V F P C + A C GDSGGPL+CDG +QGI S+
Sbjct: 173 CAEVKIF--PQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGS 230
Query: 222 WGCATRLFPDFFTRVALYVDWIRSTL 247
C P +T + Y+DWI+ +
Sbjct: 231 DPCGRSDKPGVYTNICRYLDWIKKII 256
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 122 bits (307), Expect = 2e-28
Identities = 84/254 (33%), Positives = 132/254 (51%), Gaps = 24/254 (9%)
Query: 10 LASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTA 69
L +LLAL I+ G E +PHS+P+ A+L + CG TLI P ++LTA
Sbjct: 4 LQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRL---LCGATLIAPRWLLTA 60
Query: 70 AHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFL-----NNYDAENKLNDVLLIQL 124
AHCL+ P+ +V+ LG HN++ +E +Q + + F N+ ++ ND++L+++
Sbjct: 61 AHCLK--PRYIVH--LGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKM 116
Query: 125 SSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVTFF-- 181
+SP +++ +V + L + V GT CL GWG + L+ N+T++
Sbjct: 117 ASPVSITWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 182 --CRPHNI-----CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFT 234
P NI C V C GDSGGPL+C+ +QGI S+ CA P +T
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234
Query: 235 RVALYVDWIRSTLR 248
+V YVDWI+ T++
Sbjct: 235 KVCKYVDWIQETMK 248
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 122 bits (307), Expect = 2e-28
Identities = 84/254 (33%), Positives = 132/254 (51%), Gaps = 24/254 (9%)
Query: 10 LASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTA 69
L +LLAL I+ G E +PHS+P+ A+L + CG TLI P ++LTA
Sbjct: 36 LQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRL---LCGATLIAPRWLLTA 92
Query: 70 AHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFL-----NNYDAENKLNDVLLIQL 124
AHCL+ P+ +V+ LG HN++ +E +Q + + F N+ ++ ND++L+++
Sbjct: 93 AHCLK--PRYIVH--LGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKM 148
Query: 125 SSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVTFF-- 181
+SP +++ +V + L + V GT CL GWG + L+ N+T++
Sbjct: 149 ASPVSITWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206
Query: 182 --CRPHNI-----CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFT 234
P NI C V C GDSGGPL+C+ +QGI S+ CA P +T
Sbjct: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266
Query: 235 RVALYVDWIRSTLR 248
+V YVDWI+ T++
Sbjct: 267 KVCKYVDWIQETMK 280
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 122 bits (307), Expect = 2e-28
Identities = 84/254 (33%), Positives = 132/254 (51%), Gaps = 24/254 (9%)
Query: 10 LASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTA 69
L +LLAL I+ G E +PHS+P+ A+L + CG TLI P ++LTA
Sbjct: 4 LQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRL---LCGATLIAPRWLLTA 60
Query: 70 AHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFL-----NNYDAENKLNDVLLIQL 124
AHCL+ P+ +V+ LG HN++ +E +Q + + F N+ ++ ND++L+++
Sbjct: 61 AHCLK--PRYIVH--LGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKM 116
Query: 125 SSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPA-QVLQELNVTVVTFF-- 181
+SP +++ +V + L + V GT CL GWG + L+ N+T++
Sbjct: 117 ASPVSITWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 182 --CRPHNI-----CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFT 234
P NI C V C GDSGGPL+C+ +QGI S+ CA P +T
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234
Query: 235 RVALYVDWIRSTLR 248
+V YVDWI+ T++
Sbjct: 235 KVCKYVDWIQETMK 248
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 122 bits (305), Expect = 4e-28
Identities = 83/241 (34%), Positives = 123/241 (51%), Gaps = 28/241 (11%)
Query: 27 EIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHC-LRDIPQRLVNVVL 85
EI+GG E PHSRP+MAS+Q G+ H CGG LI P +VLTAAHC R + VVL
Sbjct: 26 EIIGGKEVSPHSRPFMASIQYGGH---HVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 82
Query: 86 GAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQ 144
GAH++ E ++Q + + + + ++ + ND++L++L + A L+ V + + +
Sbjct: 83 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 141
Query: 145 PVPHGTQCLAMGWGRVGAHDP----PAQVLQELNVTVVTF-------------FCRPHNI 187
+ GT+C GW GA DP P+ L+E+ VTV++ F +
Sbjct: 142 SLRSGTKCKVTGW---GATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMV 198
Query: 188 CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVA-LYVDWIRST 246
C + + C GDSGGPLIC G+ I S C P +T + Y WI+S
Sbjct: 199 CAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGG-HECGVATKPGIYTLLTKKYQTWIKSN 257
Query: 247 L 247
L
Sbjct: 258 L 258
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 121 bits (304), Expect = 5e-28
Identities = 90/248 (36%), Positives = 119/248 (47%), Gaps = 32/248 (12%)
Query: 25 AAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDI----PQRL 80
+A IVGG AQP + P+ SL + G H CGG+LI PS+VL+AAHC P
Sbjct: 44 SARIVGGSNAQPGTWPWQVSLH---HGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAE 100
Query: 81 VNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDVLLIQLSSPANLSASVATVQL 139
+V+LG H+ +VA + + NY D+ L++L+SPA+L +V V L
Sbjct: 101 WSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCL 160
Query: 140 PQQDQPVPHGTQCLAMGWGRVGAHD--PPAQVLQELNVTV-----------------VTF 180
P+ HGT C A GWG V D P VLQE+ + + +T
Sbjct: 161 PRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTL 220
Query: 181 FCRPHNICTFVPRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRV 236
P +C P + C GDSGGPL+C+ GI SF +GC R P FT V
Sbjct: 221 QILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFG-FGCGRRNRPGVFTAV 279
Query: 237 ALYVDWIR 244
A Y WIR
Sbjct: 280 ATYEAWIR 287
Score = 55.8 bits (133), Expect = 3e-08
Identities = 64/241 (26%), Positives = 100/241 (41%), Gaps = 34/241 (14%)
Query: 31 GHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNV 90
G +P + P+ A + + PGS C G L+ S+VL A C D P +
Sbjct: 326 GKAPRPGAWPWEAQVMV---PGSRPCHGALVSESWVLAPASCFLD-PNSSDSPPRDLDAW 381
Query: 91 RTQEPTQQHFS-VAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHG 149
R P++ VA++ + + + +D+ L+QL +P NLSA+ V LP + G
Sbjct: 382 RVLLPSRPRAERVARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPG 441
Query: 150 TQCLAMGWGR-VGAHDPPAQVLQELNVTVVTFFCR----------------PHNIC-TFV 191
++C WGR A P A + EL + ++C PH +C +
Sbjct: 442 SRCRLARWGRGEPALGPGALLEAEL---LGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQ 498
Query: 192 PRRKAGICFGDSGGPLICD----GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247
+ + G C+ DS L+C + GI F GC L P F + + WI
Sbjct: 499 EKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPS-GC---LRPRAFFPLQTHGPWISHVT 554
Query: 248 R 248
R
Sbjct: 555 R 555
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/217 (22%), Positives = 82/217 (37%), Gaps = 20/217 (9%)
Query: 40 PYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCL-----RDIPQRLVNVVLGAHNVRTQE 94
P++A + + G+ C G L+ P +VL A HC+ +P + V LG +
Sbjct: 602 PWLAEVHVAGD---RVCTGILLAPGWVLAATHCVLRPGSTTVP--YIEVYLGRAGA-SSL 655
Query: 95 PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLA 154
P S + + + L++LSS S S + L +P G C
Sbjct: 656 PQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICL--HPAGIPPGASCWV 713
Query: 155 MGWGRVGAHDPPAQVLQELNVTVVTFFCR----PHNICTFVPRRKAGICFGDSGGPLICD 210
+GW P A + L + + P +C + C S PL+C
Sbjct: 714 LGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQ 773
Query: 211 GIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTL 247
+ +G S+++ G A + + F + WI T+
Sbjct: 774 -MTEG--SWILVGMAVQGSRELFAAIGPEEAWISQTV 807
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 121 bits (303), Expect = 7e-28
Identities = 91/268 (33%), Positives = 131/268 (48%), Gaps = 52/268 (19%)
Query: 15 LALLLSGAARA----AEIVGGHEAQPHSRPYMASLQMRGNPGSHF----CGGTLIHPSFV 66
LAL L G A + IVGG E + HS+P+ A+L HF CGG L+H +V
Sbjct: 8 LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALY-------HFSTFQCGGILVHRQWV 60
Query: 67 LTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVF---------LNNYDA---EN 114
LTAAHC+ D Q + LG HN+ E T Q V++ F L N+ E+
Sbjct: 61 LTAAHCISDNYQ----LWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADED 116
Query: 115 KLNDVLLIQLSSPAN-LSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHD--------- 164
+D++L++L+ PA+ ++ +V V+LP ++ V G+ CLA GWG + +
Sbjct: 117 YSHDLMLLRLTEPADTITDAVKVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQC 174
Query: 165 -----PPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSF 219
P ++ +V VT F +C C GDSGGPL+CDG++QG+ S+
Sbjct: 175 VDLKILPNDECKKAHVQKVTDFM----LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSW 230
Query: 220 VIWGCATRLFPDFFTRVALYVDWIRSTL 247
C T P RV YV WI T+
Sbjct: 231 GYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 119 bits (299), Expect = 2e-27
Identities = 89/267 (33%), Positives = 134/267 (50%), Gaps = 31/267 (11%)
Query: 10 LASVLLALLLSGAARAAE---------IVGGHEAQPHSRPYMASLQMRGN-PGSHFCGGT 59
+ ++LL+ L++GA + +VGG EA+P+S P+ SLQ N H CGG+
Sbjct: 2 IRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGS 61
Query: 60 LIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN---NYDAENKL 116
LI S+VLTAAHC+ R V LG HN+ E SV+++ ++ N + +K
Sbjct: 62 LIANSWVLTAAHCISS--SRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKG 119
Query: 117 NDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVT 176
ND+ L++L++P +L+ + LP +P+ C GWGR+ + VLQ+ +
Sbjct: 120 NDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLL 179
Query: 177 VVTFFCRPHNI-------CTFVPRRKAGI---CFGDSGGPLIC---DG--IIQGIDSF-V 220
VV + + + + G+ C GDSGGPL C DG + GI SF
Sbjct: 180 VVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGS 239
Query: 221 IWGCATRLFPDFFTRVALYVDWIRSTL 247
GC P FTRV+ Y+DWI S +
Sbjct: 240 RLGCNYYHKPSVFTRVSNYIDWINSVI 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,659,694
Number of Sequences: 37866
Number of extensions: 478732
Number of successful extensions: 2036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1397
Number of HSP's gapped (non-prelim): 210
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.