Guide to the Human Genome
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Name: TRHDE Sequence: fasta or formatted (1024aa) NCBI GI: 7019561
Description:

thyrotropin-releasing hormone degrading enzyme

Referenced in:

Aminopeptidases
Peptide and Protein G-coupled Signals

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.6         78           3
 C cysteine            0.9          9           1
 D aspartate           5.0         51           2
 E glutamate           6.0         61           3
 F phenylalanine       4.5         46           2
 G glycine             5.7         58           2
 H histidine           3.2         33           2
 I isoleucine          5.5         56           3
 K lysine              4.2         43           2
 L leucine            11.3        116           2
 M methionine          2.0         20           1
 N asparagine          5.4         55           2
 P proline             3.7         38           2
 Q glutamine           3.4         35           2
 R arginine            6.0         61           2
 S serine              6.6         68           2
 T threonine           5.1         52           3
 V valine              7.2         74           3
 W tryptophan          2.7         28           2
 Y tyrosine            4.1         42           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyrotropin-releasing hormone degrading enzyme 
ANPEP                 0.265   membrane alanine aminopeptidase precursor 
ENPEP                 0.233   glutamyl aminopeptidase 
ERAP2                 0.228   endoplasmic reticulum aminopeptidase 2 
ERAP2                 0.228   endoplasmic reticulum aminopeptidase 2 
ERAP1                 0.220   type 1 tumor necrosis factor receptor shedding amino...
ERAP1                 0.220   type 1 tumor necrosis factor receptor shedding amino...
LVRN                  0.217   laeverin 
LNPEP                 0.211   leucyl/cystinyl aminopeptidase isoform 1 
LNPEP                 0.211   leucyl/cystinyl aminopeptidase isoform 2 
NPEPPS                0.177   aminopeptidase puromycin sensitive 
LTA4H                 0.029   leukotriene A4 hydrolase 
RNPEP                 0.027   arginyl aminopeptidase 
RNPEPL1               0.020   arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho...
ZNF469                0.005   zinc finger protein 469 
HEXIM2                0.005   hexamthylene bis-acetamide inducible 2 
TAF2                  0.005   TBP-associated factor 2 
COL5A1                0.005   alpha 1 type V collagen preproprotein 
COL4A2                0.005   alpha 2 type IV collagen preproprotein 
EDARADD               0.004   EDAR-associated death domain isoform A 
EDARADD               0.004   EDAR-associated death domain isoform B 
LOC100293107          0.004   PREDICTED: hypothetical protein 
LOC100290679          0.004   PREDICTED: hypothetical protein XP_002347834 
LOC100288571          0.004   PREDICTED: hypothetical protein XP_002343612 
GRIP2                 0.004   glutamate receptor interacting protein 2 
COL3A1                0.004   collagen type III alpha 1 preproprotein 
COL14A1               0.004   collagen, type XIV, alpha 1 
WNK2                  0.003   WNK lysine deficient protein kinase 2 
COL5A2                0.003   alpha 2 type V collagen preproprotein 
LOC100287820          0.003   PREDICTED: hypothetical protein XP_002343297 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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