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Search of human proteins with 6912246
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912246 CD3E antigen, epsilon polypeptide associated protein
[Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912246 CD3E antigen, epsilon polypeptide associated protein ... 1030 0.0
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 72 2e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 65 1e-10
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 62 9e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 62 1e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 61 2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 61 2e-09
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 60 5e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 59 1e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 59 1e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 59 1e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 59 1e-08
gi|30795231 brain abundant, membrane attached signal protein 1 [... 57 3e-08
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 57 4e-08
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 57 4e-08
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 57 5e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 56 9e-08
gi|157738619 smoothelin-like 1 [Homo sapiens] 53 6e-07
gi|48375173 microtubule-associated protein 6 isoform 1 [Homo sap... 52 1e-06
gi|104526627 triadin [Homo sapiens] 52 1e-06
gi|15559211 RE1-silencing transcription factor [Homo sapiens] 52 2e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 2e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 50 5e-06
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 50 5e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 50 5e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 6e-06
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 49 8e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 49 8e-06
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 49 1e-05
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 49 1e-05
>gi|6912246 CD3E antigen, epsilon polypeptide associated protein
[Homo sapiens]
Length = 510
Score = 1030 bits (2664), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MEEPQAGDAARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRH 60
MEEPQAGDAARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRH
Sbjct: 1 MEEPQAGDAARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRH 60
Query: 61 VPLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEG 120
VPLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEG
Sbjct: 61 VPLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEG 120
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQ 180
PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQ
Sbjct: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQ 180
Query: 181 VTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLE 240
VTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLE
Sbjct: 181 VTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLE 240
Query: 241 PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGME 300
PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGME
Sbjct: 241 PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGME 300
Query: 301 PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP 360
PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP
Sbjct: 301 PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP 360
Query: 361 GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS 420
GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS
Sbjct: 361 GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS 420
Query: 421 TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE 480
TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE
Sbjct: 421 TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE 480
Query: 481 MPGPPLNSESGEEAPTGRDKKRKQQQQQPV 510
MPGPPLNSESGEEAPTGRDKKRKQQQQQPV
Sbjct: 481 MPGPPLNSESGEEAPTGRDKKRKQQQQQPV 510
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 71.6 bits (174), Expect = 2e-12
Identities = 85/394 (21%), Positives = 149/394 (37%), Gaps = 39/394 (9%)
Query: 136 SPPPQIP--PGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNG 193
+P P +P P L+P + + PVT ++ +T G+K + T V A+
Sbjct: 1157 TPEPVVPTAPELQP---STSTDQPVTSEPTSQ----VTRGRKSRSSVKTPETVVPTALEL 1209
Query: 194 HGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTE--PTVETLEPLGVLFPS--T 249
+ D + S + +K +K PE P E P+ T +P+ P+
Sbjct: 1210 QPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV-TSEPTYQA 1268
Query: 250 TKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKK--RKRQKGTEGMEPEEGVTV 307
T+ RK +T EP T + + +T PT + R R + PE V
Sbjct: 1269 TRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPT 1328
Query: 308 ESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQ 367
+ Q+ + P P ++ + ++ P E+ P+ PE+ P S +
Sbjct: 1329 APELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNP--ESTVPIAPELPPSTST------E 1380
Query: 368 QPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKK 427
QP +P ++A +K + + T+ P + P D PTS + +
Sbjct: 1381 QPVTPEPTSRATRG---RKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRT 1437
Query: 428 KERGHTVTEPIQPLEPEL--------PGEGQPEARATPGSTKKRKKQSQESRMPETVPQE 479
E + P PEL P +P ++AT G T + ++ E+ +P T P+
Sbjct: 1438 NRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVP-TAPEL 1496
Query: 480 EMPG---PPLNSESGEEAPTGRDKKRKQQQQQPV 510
+ P+ SE GR + + + V
Sbjct: 1497 QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETV 1530
Score = 70.5 bits (171), Expect = 3e-12
Identities = 84/380 (22%), Positives = 133/380 (35%), Gaps = 39/380 (10%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFC----------------AFGGNPPVTGPRSA 164
P+ S S QP+ + P Q+ G + R + + PVT ++
Sbjct: 1166 PELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTS 1225
Query: 165 LAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEP 224
A T G+K + T PV A + D + S + +K +K P
Sbjct: 1226 QA----TRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTP 1281
Query: 225 EAAGPVGTE--PTVETLEPLGVLFPS-TTKKRKKPKGKETFEPEDKTVKQEQINTEPLED 281
E P E P+ T P+ S TT+ R +T E T + QI+T +
Sbjct: 1282 EPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQP 1341
Query: 282 TVLSPTKK--RKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAM 339
PT + R R + PE V + + + P P ++ + K + +
Sbjct: 1342 VTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSG 1401
Query: 340 MEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEP 399
P E + P P+++P S QP +P +QA + + K + TV P
Sbjct: 1402 KTP--ETLVPTAPKLEPSTST------DQPVTPEPTSQATRGRTNRSSVKTPE---TVVP 1450
Query: 400 ETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEG---QPEARAT 456
+ P D PTS + + E + P PEL QP
Sbjct: 1451 TAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1510
Query: 457 PGSTKKRKKQSQESRMPETV 476
T + +K + PETV
Sbjct: 1511 TSRTTRGRKNRSSVKTPETV 1530
Score = 58.2 bits (139), Expect = 2e-08
Identities = 106/496 (21%), Positives = 174/496 (35%), Gaps = 73/496 (14%)
Query: 15 PPNFTAKPPASESP------RFSLEALTGPDTELWLIQAPADFAPECFNGRHVPLSGSQI 68
P T +P SE R S ++ P+T ++ + P R V S+
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPET---VVPTALELQPSTSTDRPVT---SEP 1223
Query: 69 VKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLSGS 128
G+++R V + P A L PST +T E Q+ G
Sbjct: 1224 TSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-----------EPTYQATRGR 1272
Query: 129 PLQPIPASPPPQIP--PGLRPRFCAFGGNPPVTGPRSALAPNLLT--SGKKKKEMQVTEA 184
+ +P P +P P LRP + + PVT ++ T S K E V A
Sbjct: 1273 KNRSSVKTPEPVVPTAPELRP---STSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTA 1329
Query: 185 PVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQ-LKEPEAAGPVGTE--PTVETLEP 241
P Q + + + +P+ R + + N +K PE+ P+ E P+ T +P
Sbjct: 1330 PELQISTSTDQPV-------TPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQP 1382
Query: 242 LGVLFPSTT-------KKRKKPKGKETFEP-----EDKTVKQEQINTEPLEDTVLSPTKK 289
+ P T K R K ET P E T + + EP T+
Sbjct: 1383 VT---PEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQA----TRG 1435
Query: 290 RKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEP 349
R + + E E QP + + P P ++ + + ++ P E + P
Sbjct: 1436 RTNRSSVKTPETVVPTAPELQPSTSTD--QPVTPEPTSQATRGRTDRSSVKTP--ETVVP 1491
Query: 350 VEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELP 409
PE++ + + QP ++P ++ +K + + TV P + P
Sbjct: 1492 TAPELQ------ASASTDQPVTSEPTSRTTRG---RKNRSSVKTPETVVPAAPELQPSTS 1542
Query: 410 DDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQE 469
D PTS + + E I P+ PEL TP T R + +
Sbjct: 1543 TDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPT-SRATRCRT 1601
Query: 470 SRMPETVPQEEMPGPP 485
+R P+ +P P
Sbjct: 1602 NRSSVKTPEPVVPTAP 1617
Score = 54.3 bits (129), Expect = 3e-07
Identities = 82/378 (21%), Positives = 135/378 (35%), Gaps = 57/378 (15%)
Query: 119 EGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKE 178
EG Q G P P PG+ G + GP SA P+ SG +
Sbjct: 952 EGGSQDQKGQASSPTPE-------PGV--------GAGDLPGPTSAPVPSGSQSGGRG-- 994
Query: 179 MQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTV-E 237
+PV+ + G L M +R +K + P+A P PTV E
Sbjct: 995 -----SPVSPRR-HQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLP----PTVPE 1044
Query: 238 TLEPLGVLFPSTTKKRKKPKGK-----ETFEPEDKTVKQEQINTEPLE--DTVLSP--TK 288
P S ++K P + +P + +Q+ P + L P K
Sbjct: 1045 APAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPK 1104
Query: 289 KRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAME 348
+ R + + M P + +P + P P ++ + + ++ P E +
Sbjct: 1105 PKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTP--EPVV 1162
Query: 349 PVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPEL 408
P PE++P S QP ++P +Q +K++ + TV P + P
Sbjct: 1163 PTAPELQPSTST------DQPVTSEPTSQVTRG---RKSRSSVKTPETVVPTALELQPST 1213
Query: 409 PDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPEL--------PGEGQPEARATPGST 460
D + PTS + +K EP+ P PEL P +P +AT G
Sbjct: 1214 STDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRK 1273
Query: 461 KKRKKQSQESRMPETVPQ 478
+ ++ E +P T P+
Sbjct: 1274 NRSSVKTPEPVVP-TAPE 1290
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/409 (20%), Positives = 143/409 (34%), Gaps = 81/409 (19%)
Query: 82 VLSSCPQAGEATLLAPSTEAGGGLTCASAP-------QGTLRILEGPQQSLSGSPLQPIP 134
V S G + ++P G L C P + ++ G Q+S +P
Sbjct: 984 VPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVP 1043
Query: 135 ASP-PPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKE---MQVTEAPVTQEA 190
+P PPQ P L + PP+ P L P++ + +K ++ + EAP++ E
Sbjct: 1044 EAPAPPQKP--LNSQSQKHLAPPPLLSP---LLPSIKPTVRKTRQDGSQEAPEAPLSSEL 1098
Query: 191 VNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTT 250
H P+ +R +K + + P FP+T+
Sbjct: 1099 EPFH-----------PKPKIRTRKSSR---------------------MTP----FPATS 1122
Query: 251 KKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQ 310
EP T + + +P T+ R + + EP E Q
Sbjct: 1123 AAP---------EPHPSTSTAQPVTPKPTSQA----TRSRTNRSSVKTPEPVVPTAPELQ 1169
Query: 311 PQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPE 370
P + + P ++ + K + ++ P E + P E++P S +P
Sbjct: 1170 PSTSTD--QPVTSEPTSQVTRGRKSRSSVKTP--ETVVPTALELQPSTST------DRPV 1219
Query: 371 GAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKER 430
++P +QA + + K + PE + P D + PT + +K
Sbjct: 1220 TSEPTSQATRGRKNRSSVKTPEPVVPTAPELQ---PSTSTDQPVTSEPTYQATRGRKNRS 1276
Query: 431 GHTVTEPIQPLEPELPGEGQPEARATPGSTKK--RKKQSQES-RMPETV 476
EP+ P PEL + TP T + R + + S + PETV
Sbjct: 1277 SVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETV 1325
Score = 49.3 bits (116), Expect = 8e-06
Identities = 90/424 (21%), Positives = 149/424 (35%), Gaps = 58/424 (13%)
Query: 75 GKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEG-PQQSLSGSPLQPI 133
G+++R V + A L PST +T P+ T R G +S +P +
Sbjct: 1517 GRKNRSSVKTPETVVPAAPELQPSTSTDQPVT----PEPTSRATRGRTNRSSVKTPESIV 1572
Query: 134 PASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNG 193
P I P L+P + N VT ++ A T+ K T PV A
Sbjct: 1573 P------IAPELQP---STSRNQLVTPEPTSRATRCRTNRSSVK----TPEPVVPTAPEP 1619
Query: 194 HGALEVDMALGSPEMDVRKKKKKKNQQ-LKEPEAAGPVGTE-----PTVETLEPLGVLFP 247
H D + +P++ R ++K N+ +K P+ P ++ PT +++ P +
Sbjct: 1620 HPTTSTDQPV-TPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQG 1678
Query: 248 STTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTV 307
+K + + P + +P+ ++ KRQ+ G +
Sbjct: 1679 GQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAA-GNPGSLAAPI 1737
Query: 308 ESQP-QVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAP 366
+ +P +EP +A R + G + E T EP P++ LE+P
Sbjct: 1738 DHKPCSAPLEPKSQA-------SRNQRWGAVRAAESLTAIPEPASPQL--LETPIHASQI 1788
Query: 367 QQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKK 426
Q+ E A PK +++ P P +PQ S K
Sbjct: 1789 QKVEPAGRSRFTPELQPKASQSRKRSLATMDSP---------PHQKQPQRGEVSQKTVII 1839
Query: 427 KKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPL 486
K+E T E PG+ + PG K+ Q P +P + L
Sbjct: 1840 KEEEEDTA---------EKPGKEEDVVTPKPGKRKR----DQAEEEPNRIPSRSLRRTKL 1886
Query: 487 NSES 490
N ES
Sbjct: 1887 NQES 1890
Score = 38.5 bits (88), Expect = 0.015
Identities = 59/293 (20%), Positives = 108/293 (36%), Gaps = 36/293 (12%)
Query: 229 PVGTEPTVETLEPLGVLFPSTTKKRKK---PKGKETFEPEDKTVKQEQINTEPLEDTVLS 285
P+ E + + L ST +R+ P G+E + T K + N ED L
Sbjct: 639 PISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGT-KDSEDNYGDSEDLDLQ 697
Query: 286 PTKKRKRQKGTEGMEPEEGVTVES---QPQVKVEP----------LEEAIPLPPTKKRKK 332
T+ +G E ++ E ++ P ++ P L+E + T+
Sbjct: 698 ATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCL 757
Query: 333 EKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQA---------QAALAAP 383
+ + + +P +E P + P + G P+ P +P + P
Sbjct: 758 RESEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIP 817
Query: 384 KKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEP 443
K+ ++ + +E ETE + PE D+ + T K K+ +E+ + Q E
Sbjct: 818 KETAERVGPERGPLERETEKLLPERQTDVTGEEELT---KGKQDREQKQLLARDTQRQES 874
Query: 444 ELPGEGQPEARATPG-------STKKRKKQSQESRMPETVPQEEMPGPPLNSE 489
+ GE R S + ++KQ Q+ +P + E+ P N E
Sbjct: 875 DKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRE 927
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 65.5 bits (158), Expect = 1e-10
Identities = 65/274 (23%), Positives = 114/274 (41%), Gaps = 28/274 (10%)
Query: 251 KKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQ 310
K +K K E E E V+++ T+ E+ K+ K ++G E EE +
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498
Query: 311 PQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPE 370
+ K P EEA P K+ K + E E PE + +SP +P++ +
Sbjct: 499 EETKSPPAEEAAS--PEKEAKSP-----VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 371 GAKPQAQAALAAPKKKT--KKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKK 428
P + A + P+ K+ K+E + A V+ + P + P A + K K K
Sbjct: 552 --SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 429 ERGHTVTEPIQPLEPELPGEGQ---PEARATPGSTKKRKKQSQESRMPETVPQEEMPGP- 484
E + E P++ E + PE +P TK+ K ++++ PE +EE P
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP--TKEEAKSPEKAKSPE---KEEAKSPE 664
Query: 485 ----PLNSESGE----EAPTGRDKKRKQQQQQPV 510
P+ +E+ ++P + K ++ + PV
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Score = 63.2 bits (152), Expect = 6e-10
Identities = 78/291 (26%), Positives = 122/291 (41%), Gaps = 44/291 (15%)
Query: 174 KKKKEMQVTEAPVTQEAVNGHGALE-VDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGT 232
++ K + ++PV +EA A V SPE + +K K +K PEA P
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK-AKSPEKAKTLDVKSPEAKTPAKE 772
Query: 233 EPTVETLEPLGVLFPSTTK-----------KRKKPKGKETFEPEDKTVKQEQINT----- 276
E + FP K K K P ++ PE + K+E++ +
Sbjct: 773 EARSPADK-----FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827
Query: 277 -EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQ-------PQVKVEPLEE-AIPLPPT 327
+P E V P KK + +K + EE + + P+ KVE +E A+ P
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Query: 328 KK--RKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGT--MAPQQPEGAKPQ-----AQA 378
K KKE+ + P E P + E+K P +A ++P+ AK + A+
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 379 ALAAPKKK-TKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKK 428
AAP+KK TK+EK + +P+TE E DD P+ K +K +K
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKAKE--DDKTLSKEPSKPKAEKAEK 996
Score = 61.2 bits (147), Expect = 2e-09
Identities = 79/388 (20%), Positives = 148/388 (38%), Gaps = 45/388 (11%)
Query: 160 GPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQ 219
G +P + +KE ++PV +EA + A + +V+ +K K+
Sbjct: 497 GEEETKSPPAEEAASPEKE---AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553
Query: 220 QLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTE-- 277
+E ++ + E P V P K K + K E + + + E
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Query: 278 -------PLEDTVLSPTKKRKRQKG-----TEGMEPEEGVTVESQ----PQVKVEPLEEA 321
P+++ SP + + +K E PE+ + E + P+ P++
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673
Query: 322 IPLP-----PTKKRKK--EKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAP-----QQP 369
P P K K EK + + E + P + +SP +P + P
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 370 EGAKPQAQAALAAPKKKTKKEKQQDATVE-PETEVVGPE---LPDDLEPQAAPTSTKKKK 425
E AK + +P+K EK + V+ PE + E P D P+ A + K++
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 426 KKKERGHT-VTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGP 484
K E+ + + E + E E+P + E +P +++ ++ + P+ +E+ P
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIP---KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850
Query: 485 PLNSE----SGEEAPTGRDKKRKQQQQQ 508
P E EEAP K K ++++
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Score = 57.8 bits (138), Expect = 2e-08
Identities = 68/334 (20%), Positives = 125/334 (37%), Gaps = 27/334 (8%)
Query: 188 QEAVNGHGALEVDMALGSPEMD-----VRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPL 242
+E G G + + G P++ ++ K ++K + +++ E + E T ET +
Sbjct: 409 EECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET-QVT 467
Query: 243 GVLFPSTTKKRKKPKGKETFEPEDKTVK--QEQINTEPLEDTVLSPTKKRKRQKGTEGME 300
+ K+ K+ +GKE E++ + +E+ + P E+ SP K+ K E
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAA-SPEKEAKSPVKEEAKS 526
Query: 301 PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP 360
P E + E EEA P + + EK + E E PE + +SP
Sbjct: 527 PAEAKSPEK---------EEA--KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 361 GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS 420
+ PE AK A+ +P + EK + E + P E ++
Sbjct: 576 AEV---KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 421 TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE 480
+K K P + PE PE +P + + + +S + E
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692
Query: 481 MPGPPLNSESGE----EAPTGRDKKRKQQQQQPV 510
P+ E+ ++P + K ++ + PV
Sbjct: 693 KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Score = 55.8 bits (133), Expect = 9e-08
Identities = 87/368 (23%), Positives = 143/368 (38%), Gaps = 34/368 (9%)
Query: 164 ALAPNLLTSGKKK--KEMQVTEAPVTQEAVNGHGALE-VDMALGSPEMDVRKKKKKKNQQ 220
A +P S +K+ K + ++PV EA + A V SPE K K ++
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE----KAKSPVKEE 701
Query: 221 LKEPEAA-GPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPL 279
K PE A PV E V + T ++ K KE + +K E+ T +
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 280 EDT-VLSPTKKRKRQKGTEGMEPEEGVTVES--QPQVKVEPLEEAIPLPPTKKRKKEKGQ 336
+ +P K+ R + E + E P+ PL+E P + KKE+
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE-- 819
Query: 337 MAMMEPGTEAMEPVEPEMK-PLESPGGTMAPQQPEGAKPQAQAALAAPKK---KTKKEKQ 392
+ P E +P E ++K P + AP P+ + + APKK K K E++
Sbjct: 820 --VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 393 QDATVE-PETEVVGPELPDDLEPQAAPTSTK------------KKKKKKERGHTVTEPIQ 439
++ VE P+ V + + + + PT K K K+K E + +
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 440 PLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRD 499
EP P E + EA TK+ K + E + P+T + + L+ E + +
Sbjct: 938 AKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEK-PKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 500 KKRKQQQQ 507
K Q+
Sbjct: 996 KSSSTDQK 1003
Score = 55.1 bits (131), Expect = 2e-07
Identities = 75/317 (23%), Positives = 119/317 (37%), Gaps = 33/317 (10%)
Query: 205 SPEMDVRKKKKKKNQQLKEP-EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGK---E 260
SPE K K ++ K P EA PV E P V P K K + K +
Sbjct: 600 SPE----KAKSPVKEEAKSPAEAKSPVKEEAK----SPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 261 TFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVT-----VESQPQVKV 315
PE + K + P++ SP K + K E PE+ + +S + K
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA-EAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 316 EPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQ 375
EEA K KE+ + E PE T+ + PE P
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 376 AQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVT 435
+ A + K +K K + EV PE + A K+ KK+E V
Sbjct: 771 KEEARSPADKFPEKAKS-----PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 436 EPIQPLE---PELPGEGQPE-ARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESG 491
E +P E E P + + E A ATP + +K+ + +E+ P++E P P + +
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA------PKKEAPKPKVEEKKE 879
Query: 492 EEAPTGRDKKRKQQQQQ 508
++ K + ++++
Sbjct: 880 PAVEKPKESKVEAKKEE 896
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 62.4 bits (150), Expect = 9e-10
Identities = 81/344 (23%), Positives = 141/344 (40%), Gaps = 46/344 (13%)
Query: 173 GKKKKEMQVTEAPVTQEAVNGHG----ALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAG 228
G+ + E +V E+ +E ALEV++ E + + + ++ ++ PEA G
Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPE----SEDVEAPEAEG 2007
Query: 229 PVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTK 288
+ E GV + + K +G+E E E +T K E + +P D V +P
Sbjct: 2008 EMQEAEEEAQPESDGV------EAQPKSEGEEAQEVEGETQKTEG-DAQPESDGVEAPEA 2060
Query: 289 KRKRQKGTEGMEPEEGVTVESQPQVKVEPLE-EAIPLPPTKKRKKEKGQMAMMEPGTEAM 347
+ + Q+ ++ EG V + E EA P + + +G+ E G EA
Sbjct: 2061 EEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE-GIEAP 2119
Query: 348 EP---VEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVV 404
E +PE + +E+P QPE +AQ A + +++ + Q+A E + E+
Sbjct: 2120 ETEGEAQPESEGIEAPEAE-GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Query: 405 GPELPD-----------------------DLEPQAAPTSTKKKKKKKERGHTVTEPIQPL 441
G E P+ +LE AP + ++ + + E G E
Sbjct: 2179 GVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE-GVETPEAEGEA 2237
Query: 442 EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPP 485
+PE GE Q E + +P + + + S VP E+ P PP
Sbjct: 2238 QPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP-EDRPTPP 2280
Score = 59.3 bits (142), Expect = 8e-09
Identities = 79/366 (21%), Positives = 145/366 (39%), Gaps = 46/366 (12%)
Query: 161 PRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQ 220
P + L T G+ + E + EA +EA A E + PE +V + ++ + +
Sbjct: 1917 PETESVEALETEGEDEPESEGAEAQEAEEA-----AQEAE-GQTQPESEVIESQEAEEEA 1970
Query: 221 LKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQE-QINTEPL 279
+PE+ E VET E G +P+ ++ PE + QE + +P
Sbjct: 1971 --QPESEDVEALEVEVETQEAEG---------EAQPESEDVEAPEAEGEMQEAEEEAQPE 2019
Query: 280 EDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKE-KGQMA 338
D V + Q +EG E +E + + +P + + P ++ +E +G++
Sbjct: 2020 SDGV-------EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQ 2072
Query: 339 MME----------PGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTK 388
E EA +PE + +E+P Q+ EG + A P+ +
Sbjct: 2073 EAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGI 2132
Query: 389 KEKQQDATVEPETEVVGPELPDDLEPQAAPTSTK-KKKKKKERGHTVTEPIQPLEPELPG 447
+ + + +PE+E V + D E +A P S + ++ +E E ++ PE G
Sbjct: 2133 EAPEAEGEAQPESEGVEAQ---DAEGEAQPESEGIEAQEAEEEAQPELEGVEA--PEAEG 2187
Query: 448 EGQPEARATPGSTKKRKKQSQ----ESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRK 503
E QPE+ + + Q + E+ E Q E G GE P + +
Sbjct: 2188 EAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQG 2247
Query: 504 QQQQQP 509
+++ P
Sbjct: 2248 EKKGSP 2253
Score = 55.8 bits (133), Expect = 9e-08
Identities = 70/302 (23%), Positives = 127/302 (42%), Gaps = 39/302 (12%)
Query: 221 LKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLE 280
++ PEA G E GV P ++ +G+ E ED + + +P
Sbjct: 1835 IEAPEAEGEAQPESE-------GVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887
Query: 281 DTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK-VEPLE-EAIPLPPTKKRKKEKGQMA 338
+ V +P + + Q +EG E E E+QP+ + VE LE E P ++ + ++ + A
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEK-EAQPETESVEALETEGEDEPESEGAEAQEAEEA 1946
Query: 339 MMEP------------GTEAMEPVEPEMKPLESPGGTMAPQQPEG-AKPQAQAALAAPKK 385
E EA E +PE + +E+ + Q+ EG A+P+++ A +
Sbjct: 1947 AQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAE 2006
Query: 386 KTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPEL 445
+E +++A +PE++ V +A P S ++ ++ E TE +PE
Sbjct: 2007 GEMQEAEEEA--QPESDGV----------EAQPKSEGEEAQEVEGETQKTE--GDAQPES 2052
Query: 446 PGEGQPEARATPGSTKKRKKQSQESRMPET--VPQEEMPGPPLNSESGEEAPTGRDKKRK 503
G PEA + ++++ PE+ V +E G G EAP + +K
Sbjct: 2053 DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQK 2112
Query: 504 QQ 505
+
Sbjct: 2113 AE 2114
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/331 (22%), Positives = 127/331 (38%), Gaps = 38/331 (11%)
Query: 171 TSGKKKKEMQVTEAP-VTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP 229
T G + E EAP +EA G EV A G + ++ + +PE+ G
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEG--EVQEAEGEAHPESEDVDAQEAEGEAQPESEGV 2101
Query: 230 VGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKK 289
E E + G+ P T +G+ E E + + +P + V + +
Sbjct: 2102 EAPEAEGEAQKAEGIEAPET-------EGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE 2154
Query: 290 RKRQKGTEGMEPEEGVTVESQPQVK-VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAME 348
+ Q +EG+E +E E+QP+++ VE E P + + +P E +E
Sbjct: 2155 GEAQPESEGIEAQEAEE-EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVE 2213
Query: 349 PVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKT---------KKEKQQDATVEP 399
E E + P G P+ A+P+++ KK + +E + ++ P
Sbjct: 2214 APEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP 2273
Query: 400 ETEVVGPELPDDLEP------QAAPTSTKKK------KKKKERGHTVTEPIQPLEPELPG 447
E P P P Q P+S++ +K E H + + P + + G
Sbjct: 2274 EDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSP-DAKSTG 2332
Query: 448 EGQPEARAT----PGSTKKRKKQSQESRMPE 474
E +AT ST ++++ SR PE
Sbjct: 2333 TPHAERKATRMYPESSTSEQEEAPLGSRTPE 2363
Score = 35.8 bits (81), Expect = 0.095
Identities = 46/221 (20%), Positives = 80/221 (36%), Gaps = 15/221 (6%)
Query: 266 DKTVKQEQINTEPL-EDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPL 324
D ++ N E L E+TV + + ++GTEG +E + + + EE + L
Sbjct: 1279 DSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQL 1338
Query: 325 PPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
TK E E + E +++ +E GG ++ + + +
Sbjct: 1339 EETK------------ETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGH--TVTEPIQPLE 442
+ +E ++ + E V G EL + P + +++E G EP
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG 1446
Query: 443 PELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPG 483
E P E T S +R+ SQ E P M G
Sbjct: 1447 TEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMG 1487
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 62.0 bits (149), Expect = 1e-09
Identities = 103/411 (25%), Positives = 151/411 (36%), Gaps = 77/411 (18%)
Query: 130 LQPIPASPPPQIPPGLRPRFCAFGGNPP--VTGPRSALAPNLLTSGKKKKEMQVTEAPVT 187
+ P P SPPP++ P A P V P A P + KK PV
Sbjct: 10654 IPPKPESPPPEVFE--EPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK---------PVP 10702
Query: 188 QEAVNGHGALEVDMA-LGSPEM--DVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGV 244
++ A + ++ + PE+ +V +KK K+PEA E E + V
Sbjct: 10703 EKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV 10762
Query: 245 LFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEG 304
P KK + P K P+ ++++ P+ + SP + + E + PEE
Sbjct: 10763 AVP---KKPEVPPAKVPEVPKKPVLEEKP--AVPVPERAESPPPEVYEEP--EEIAPEEE 10815
Query: 305 VTVESQPQVKVEPLEEAIPLPPT-----KKRKKEKGQMAMMEPGTEAMEPVEPEM-KPLE 358
+ E + V V EE PP KK EK + +P EA P EPE K +E
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP--EAPPPKEPEPEKVIE 10873
Query: 359 SPGGTMAPQQPEGAKPQAQAA------LAAPKKKTKKEKQQDATVE-------------- 398
P P P A P+ A PKKK ++ Q VE
Sbjct: 10874 KPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 399 ---------PETEVVGPEL----PDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPEL 445
P+ EVV + P++ EP+ P +K KK P PE
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK-------------PAVPEP 10980
Query: 446 PGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPT 496
P E P TK+ +K + +++PE P +P P + E T
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT 11031
Score = 56.6 bits (135), Expect = 5e-08
Identities = 88/394 (22%), Positives = 149/394 (37%), Gaps = 47/394 (11%)
Query: 129 PLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSAL----APNLLTSGKKKKEMQVTEA 184
P +PIP P P+ P +P+ PP + A+ P + K +V E
Sbjct: 9789 PEKPIPVKPVPEEPVPTKPK------APPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE 9842
Query: 185 P--VTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEP----EAAGPVGTEPTVET 238
P V +E + + P V K K+ + K P E A PV +
Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902
Query: 239 LEPLGVLFP----STTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQK 294
LEP V F + ++ + +E E++ + +E++ P K +K
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEK 9962
Query: 295 GTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMM--EPGTEAMEPVEP 352
+ ++ P+V +P EE +P+ KK K ++ + +P E PV P
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKP-EEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPV-P 10020
Query: 353 EMKPLESPGGTMAPQQPEGAKPQAQAALAAPK-------------KKTKKEKQQDATVEP 399
K +E+P + P+ P+ P+ + + APK KK E+++ V
Sbjct: 10021 VPKKVEAPPAKV-PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPK 10079
Query: 400 ETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGS 459
+ E P++P EP P + ++++ E I P E LP E P
Sbjct: 10080 KVEAPPPKVPKKREPVPVPVALPQEEEV-----LFEEEIVPEEEVLP----EEEEVLPEE 10130
Query: 460 TKKRKKQSQESRMPETVPQEEMPGPPLNSESGEE 493
+ ++ + E +P EE PP EE
Sbjct: 10131 EEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEE 10164
Score = 55.5 bits (132), Expect = 1e-07
Identities = 101/427 (23%), Positives = 161/427 (37%), Gaps = 68/427 (15%)
Query: 130 LQPIPASPPPQIP------------PGLRPRFCAFGGNPPVTGPRSALAPNLLTSGK--- 174
+ P P SPPP++P P P+ P VT + AP + K
Sbjct: 10570 IPPKPESPPPEVPEAPKEVVPEKKVPAAPPK------KPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 175 ----KKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPV 230
KK E+ T+ P + + PE K + + +EPE
Sbjct: 10624 VPPPKKPEVPPTKVPEVPKVAVPEKKV--------PEAIPPKPESPPPEVFEEPEEVAL- 10674
Query: 231 GTEPTVETL-EPLGVLFPSTTKKRKKPKGKE------TFEPEDKTVKQEQINTE--PLED 281
EP E + EP P T KKP ++ +PE VK ++ E P +
Sbjct: 10675 -EEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKK 10733
Query: 282 TVLSPTKK-----RKRQKGTEGMEPEEGVTVESQPQV---KV-----EPLEEAIPLPPTK 328
L KK K + + + PE+ V V +P+V KV +P+ E P P
Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP 10793
Query: 329 KRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQA--QAALAAPKKK 386
+R + EP E + P E E P ++PE P + P+KK
Sbjct: 10794 ERAESPPPEVYEEP--EEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKK 10851
Query: 387 TKKEKQQDA----TVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLE 442
K+ +A EPE + P+L P + K+K + + + P +
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEK 10911
Query: 443 PELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKR 502
P++P + + PG KK +K E R PE P+EE+ + + EE + K+
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPE-RKPE--PKEEVVLKSVLRKRPEEEEPKVEPKK 10968
Query: 503 KQQQQQP 509
++ ++P
Sbjct: 10969 LEKVKKP 10975
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/344 (24%), Positives = 130/344 (37%), Gaps = 60/344 (17%)
Query: 125 LSGSPLQPIPA---SPPPQI--------------PPGLRPRFCAFGGNPPVTGPRSALAP 167
L P P+P SPPP++ P +P A P V P P
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843
Query: 168 NLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVR----------KKKKKK 217
+ KK ++ EAP +E E + + P++ R + K+K
Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKEP-------EPEKVIEKPKLKPRPPPPPPAPPKEDVKEK 10896
Query: 218 NQQLKE-PEAAGPVGTE-PTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQIN 275
QLK P+ P + P L PL V P KK +K + EP+++ V + +
Sbjct: 10897 IFQLKAIPKKKVPEKPQVPEKVELTPLKV--PGGEKKVRKLLPERKPEPKEEVVLKSVLR 10954
Query: 276 TEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEE-------------AI 322
P E+ KK ++ K EP VE V E AI
Sbjct: 10955 KRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 11014
Query: 323 PLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGT-MAPQQPEGAKPQAQAALA 381
PLP + + K + ++ ++P PVEPE P+ +P + ++ E P+ +A A
Sbjct: 11015 PLPAPEPKPKPEAEVKTIKP-----PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA--A 11067
Query: 382 APKKKTK-KEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKK 424
PK K K+ + +E E + P + P AP + + K
Sbjct: 11068 KPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111
Score = 50.4 bits (119), Expect = 4e-06
Identities = 96/404 (23%), Positives = 153/404 (37%), Gaps = 72/404 (17%)
Query: 129 PLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPN----LLTSGKKK----KEMQ 180
P +P+P P P + PP P P +L K+K K +
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEA-------PPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPE 10006
Query: 181 VTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLE 240
V + PV +E V + V + +P V + KK + K P A P + E
Sbjct: 10007 VPKKPVPEEKV----PVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPE 10062
Query: 241 PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGME 300
L P K PK E P K K+ EP+ V P ++ + E +
Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEA--PPPKVPKKR----EPVPVPVALPQEEEVLFE--EEIV 10114
Query: 301 PEEGVTVESQPQVKVEPLEEAIP-----LPPTKKRKKEKGQMAMME---PGTEAMEPVEP 352
PEE V E + + E EE +P LP ++ E+ ++ E P E P E
Sbjct: 10115 PEEEVLPEEEEVLPEE--EEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP-EE 10171
Query: 353 EMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKT----------KKEKQQDATVEPETE 402
E+ P P + PE K + + PKK+ KK +++ + E E
Sbjct: 10172 EVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEE 10231
Query: 403 VVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEA--------R 454
V+ E+ + EP+ P S ++ ++ V E P PE+ + PEA
Sbjct: 10232 VLPVEVTE--EPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVE 10289
Query: 455 ATPGSTKKR-----------KKQSQESRMPET---VPQEEMPGP 484
A P K+ KK++ +++PE VP++++ P
Sbjct: 10290 APPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVP 10333
Score = 48.5 bits (114), Expect = 1e-05
Identities = 71/295 (24%), Positives = 123/295 (41%), Gaps = 38/295 (12%)
Query: 207 EMDVRKKKKKKNQQLKEPEAAGP----VGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF 262
+ +V ++ ++ K PE P V +P +E +E T+++ ++ K + T
Sbjct: 9153 QKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE-------KTSRRMEEEKVQVTK 9205
Query: 263 EPE-DKTVKQEQINTEPLEDTVLSP------TKKR--KRQKGTEGMEPEEGVTVESQPQV 313
PE K + ++ + P+++ V+ TKK +K EE V+V + P+V
Sbjct: 9206 VPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSV-TVPEV 9264
Query: 314 KVEPL-EEAIPLPPTKKRKKEKGQMAMME-PGTEAMEPVEPEMKPLESPGGTMAPQQPEG 371
+ E + EE I + +K+ + + E P E + PV P K +E P + P+ P+
Sbjct: 9265 QKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPV-PIPKKVEPPAPKV-PEVPKK 9322
Query: 372 AKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAA-PTSTKKKKKKKER 430
P+ + + PKK EP PE+P P+ P KKK+
Sbjct: 9323 PVPEEKKPVPVPKK------------EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPA 9370
Query: 431 GHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPP 485
+ E ++ Q E P + KK+ E R P +EE+P PP
Sbjct: 9371 KVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPP 9425
Score = 47.4 bits (111), Expect = 3e-05
Identities = 93/423 (21%), Positives = 157/423 (37%), Gaps = 53/423 (12%)
Query: 110 APQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNL 169
AP + +E P + P +P+P P P P A P + +
Sbjct: 9301 APVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP---AAPPKVPEVPKKPVPEEKI 9357
Query: 170 LTSGKKKKEMQVTEAP------VTQEAVNGHGALEVDMALGSPEM------DVRKKKKKK 217
KKKE + P VT+E + E PE+ + RK +K
Sbjct: 9358 PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRK 9417
Query: 218 NQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQ--IN 275
+++ P + +P E E + V P KK P+ E KTV +E+ +
Sbjct: 9418 EEEVPPPPKVPALPKKPVPE--EKVAVPVP-VAKKAPPPRA----EVSKKTVVEEKRFVA 9470
Query: 276 TEPLEDTVLSPTKKRKRQKGTEG----MEPEEGVTV------ESQPQVKVEPLEEAIPLP 325
E L V + + + E E EEGV++ E + + + E E +
Sbjct: 9471 EEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEE 9530
Query: 326 PTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKK 385
P + +EK + E E E + K + + P+ P + A + K
Sbjct: 9531 PEEYVVEEKLHIISKRVEAEPAEVTERQEKKI-----VLKPKIPAKIEEPPPAKVPEAPK 9585
Query: 386 KTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPEL 445
K EK+ A V + +V P++P++ P +KK + + EP+ E
Sbjct: 9586 KIVPEKKVPAPVPKKEKVPPPKVPEE------PKKPVPEKKVPPKVIKMEEPLPAKVTER 9639
Query: 446 PGEGQPEARATPGSTKKRKKQSQESRMPE----TVPQEEMPGPPLNSESGEEAPTGRDKK 501
+ E + TK K+ ++R+PE VP+E++ L + EE P +
Sbjct: 9640 HMQITQEEKVLVAVTK--KEAPPKARVPEEPKRAVPEEKV--LKLKPKREEEPPAKVTEF 9695
Query: 502 RKQ 504
RK+
Sbjct: 9696 RKR 9698
Score = 47.0 bits (110), Expect = 4e-05
Identities = 93/437 (21%), Positives = 161/437 (36%), Gaps = 84/437 (19%)
Query: 132 PIPAS---PPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNL------LTSGKKKKEMQVT 182
P+P PPP++P P P + P + L + ++ MQ+T
Sbjct: 9596 PVPKKEKVPPPKVPE-----------EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQIT 9644
Query: 183 E-----APVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQ--LKEPEAAGPVGTEPT 235
+ VT++ + + PE V K K K+ ++ K E V E
Sbjct: 9645 QEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEK 9704
Query: 236 VETLEPLGVLFPSTTKKRKKPKGKE---TFEPEDKTVKQEQI----------NTEPLEDT 282
V P P K+ + KE T E E +V++E+ E E T
Sbjct: 9705 VSIEAPKRE--PQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPT 9762
Query: 283 VLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPL-EEAIPL----PPTKKRKKEKGQM 337
+ ++ E E E E + + V+P+ EE +P PP K KK +
Sbjct: 9763 EEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEE 9822
Query: 338 AMMEPGTEAMEPVEPEMKPLESPGG--------TMAPQQPEGAKPQAQAALAAPKKKTKK 389
+ P + ++P P++ E P ++ ++ E A PK+ +
Sbjct: 9823 KVPVPIPKKLKPPPPKVP--EEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAE 9880
Query: 390 EKQQDATVEPETEVVGPELPDDLEPQAAPTS------------TKKKKKKKERGHTVTE- 436
EK E V PE+P +LEP+ ++++ E +TE
Sbjct: 9881 EKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEE 9940
Query: 437 ---PIQPLE-PELPGEGQPEARATPGSTKKRK---------KQSQESRMPETVPQEEMPG 483
P+ P++ PE+P + PE + KK++ + E ++P +P++E P
Sbjct: 9941 EVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKP- 9999
Query: 484 PPLNSESGEEAPTGRDK 500
PP + P +K
Sbjct: 10000 PPAKVPEVPKKPVPEEK 10016
Score = 45.8 bits (107), Expect = 9e-05
Identities = 57/265 (21%), Positives = 107/265 (40%), Gaps = 22/265 (8%)
Query: 251 KKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQ 310
+K+ PK + EP V + + E +++ TKK K EP+ V E
Sbjct: 9618 EKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV 9677
Query: 311 PQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPE 370
++K + EE PP K + K + + EA P+ +P T+ ++
Sbjct: 9678 LKLKPKREEE----PPAKVTEFRKRVVKEEKVSIEA-----PKREPQPIKEVTIMEEKER 9728
Query: 371 GAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKER 430
+ +A +++ ++ ++ D E E P + Q ++ ++ +E
Sbjct: 9729 AYTLEEEAVSVQREEEYEEYEEYDYKEFEEYE------PTEEYDQYEEYEEREYERYEEH 9782
Query: 431 GHTVTEPIQPLEPE-LPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSE 489
+TEP +P+ + +P E P P + K KK E ++P +P++ P PP E
Sbjct: 9783 EEYITEPEKPIPVKPVPEEPVPTKPKAPPA-KVLKKAVPEEKVPVPIPKKLKPPPPKVPE 9841
Query: 490 S-----GEEAPTGRDKKRKQQQQQP 509
E+ K+ K+Q +P
Sbjct: 9842 EPKKVFEEKIRISITKREKEQVTEP 9866
Score = 45.4 bits (106), Expect = 1e-04
Identities = 93/410 (22%), Positives = 152/410 (37%), Gaps = 65/410 (15%)
Query: 129 PLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGP--------RSALAPNLLTSGKKKKEMQ 180
P PI A PP +IPP + P P P + A+ + K KEM
Sbjct: 8945 PTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMT 9004
Query: 181 -----VTEAPVTQEAVNGHGALEVDMALGSPEMDV-----RKKKKKKNQQLKEPEAAGPV 230
V + P + +D++ + E+ + +K+ +K+ + + E + A
Sbjct: 9005 PREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHK 9064
Query: 231 GTEPTVETL-EPLGVL-FPSTTKKRKKPKGKETFE--PEDKTVKQEQINTEPLEDTVLSP 286
+E+ EP L T+ ++P +E E E K +++++ E ED
Sbjct: 9065 EKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQ 9124
Query: 287 TKKRKRQKGTEGMEP-----EEGVTVESQPQVKVEPLEEAIPL--------PPTKKRKKE 333
+ + EG E +E ++ Q +V E E +P PP K KK
Sbjct: 9125 EYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKP 9184
Query: 334 KGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQA-ALAAPKKKTKK--- 389
+ +E + ME + ++ + + PQ+P Q + + P TKK
Sbjct: 9185 --VIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVI 9242
Query: 390 --EKQQDAT-VEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELP 446
EK A+ E E V PE+ ++ + K+ EP P PELP
Sbjct: 9243 SEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKR---------VEP-PPKVPELP 9292
Query: 447 GEGQPEARATPGSTKK-----------RKKQSQESRMPETVPQEEMPGPP 485
+ PE A KK KK E + P VP++E PP
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPP 9342
Score = 45.4 bits (106), Expect = 1e-04
Identities = 70/331 (21%), Positives = 131/331 (39%), Gaps = 32/331 (9%)
Query: 206 PEMDVRKKKKKKNQQLKEPEA---AGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF 262
P+ V ++KK KEP A V +P E P+ V K P+ ++
Sbjct: 9320 PKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379
Query: 263 EPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEE-- 320
E+K Q P P KK ++ + EE P + +P+ E
Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK 9439
Query: 321 -AIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEM-----KPLESPGGTMAPQQPEGAKP 374
A+P+P KK + +++ E E ++ + +E ++ ++
Sbjct: 9440 VAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSE 9499
Query: 375 QAQAALAAPKKKTKKEKQQDATV-------EPETEVVGPEL---PDDLEPQAAPTSTKKK 424
+ + + ++ ++E++++A V EPE VV +L +E + A + +++
Sbjct: 9500 EEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQE 9559
Query: 425 KK---KKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRK----KQSQESRMPETVP 477
KK K + + EP PE P + PE + KK K K +E + P VP
Sbjct: 9560 KKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKP--VP 9617
Query: 478 QEEMPGPPLNSESGEEAPTGRDKKRKQQQQQ 508
++++P + E E P ++ Q Q+
Sbjct: 9618 EKKVPPKVIKME--EPLPAKVTERHMQITQE 9646
Score = 44.3 bits (103), Expect = 3e-04
Identities = 58/229 (25%), Positives = 87/229 (37%), Gaps = 36/229 (15%)
Query: 260 ETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGM-EPEEGVTVESQPQVKVEPL 318
E FE K +I+ E + PTK R++ + E + + VE + +V EP
Sbjct: 10431 EVFEKPKAPPKGPEIS-EKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPR 10489
Query: 319 EEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQA 378
+PPTK + + E E PV P KP P P+ P+ P+ +
Sbjct: 10490 -----VPPTKVPEV----LPPKEVVPEKKVPVPPAKKPEAPP--PKVPEAPKEVVPEKKV 10538
Query: 379 ALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPI 438
+ PKK PE+P P+ P + +KK E E
Sbjct: 10539 PVPPPKK--------------------PEVPPTKVPEV-PKAAVPEKKVPEAIPPKPESP 10577
Query: 439 QPLEPELPGEGQPEARATPGSTKKRKKQSQE--SRMPETVPQEEMPGPP 485
P PE P E PE + KK + + E VP++++P PP
Sbjct: 10578 PPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Score = 43.5 bits (101), Expect = 5e-04
Identities = 92/409 (22%), Positives = 151/409 (36%), Gaps = 66/409 (16%)
Query: 132 PIP---ASPP---PQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAP 185
P+P +PP P++P L P AF VT L ++++ + E
Sbjct: 9884 PVPRKEVAPPVRVPEVPKELEPEEVAFE-EEVVTHVEEYLVE------EEEEYIHEEEEF 9936
Query: 186 VTQEAVNGHGALEVDMALGSPEMDVRKK----KKKKNQQLKEPEAAGPVGTEPTVETLEP 241
+T+E V ++V P + +K KKK+ K PE P E V L P
Sbjct: 9937 ITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEV--PKKPEEKVPVLIP 9994
Query: 242 LGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEP 301
K++KP + E K V +E++ + P K + K P
Sbjct: 9995 ----------KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPV---P 10041
Query: 302 EEGVTVESQPQVKVEPL-----------EEAIPLPPTKK---------RKKEKGQMAMME 341
E+ V V + +V+ P EE P P KK +K+E + +
Sbjct: 10042 EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVAL 10101
Query: 342 PGTEAM---EPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQ------ 392
P E + E + PE + L + P++ E P+ + L ++ +E++
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVL-PEEEE-VLPEEEEVLPEEEEIPPEEEEVPPEEE 10159
Query: 393 ---QDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEG 449
++ PE EV+ P P P KK +KK E PE+P +
Sbjct: 10160 YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV 10219
Query: 450 QPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGR 498
+ + P + + E E + +EE+P P + E EE R
Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268
Score = 39.3 bits (90), Expect = 0.009
Identities = 95/407 (23%), Positives = 145/407 (35%), Gaps = 73/407 (17%)
Query: 130 LQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQE 189
L P PPP P + P+ PV P+ AP K +V + PV ++
Sbjct: 9992 LIPKKEKPPPAKVPEV-PKKPVPEEKVPVPVPKKVEAP-------PAKVPEVPKKPVPEK 10043
Query: 190 AVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEP-----EAAGPVGTEPTVETLEPLGV 244
V +V+ +P V + KK + K+P + P P P+ V
Sbjct: 10044 KVPVPAPKKVE----APPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPV 10099
Query: 245 LFPSTTKK--RKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGT------ 296
P + ++ +E PE++ V E+ P E+ VL ++ ++
Sbjct: 10100 ALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159
Query: 297 -----EGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKR----KKEKGQMAMME------ 341
E PEE V E +P+V V I T+K+ KKE+ A +
Sbjct: 10160 YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV 10219
Query: 342 -------PGTEAMEPVEPEMKPLESP-GGTMAPQQP-------EGAKPQA-----QAALA 381
P E + PVE +P E P P++P E A P+ +A
Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279
Query: 382 APKKKTKKEKQQDATVE---PETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPI 438
AP KK + A V PE +V P + P P KK +KK V P
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKK-----VLVPK 10334
Query: 439 QPLEPELPGEGQPEARATPG-----STKKRKKQSQESRMPETVPQEE 480
+ P G E + + K+R + E +P+EE
Sbjct: 10335 KEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE 10381
Score = 30.8 bits (68), Expect = 3.1
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)
Query: 171 TSGKKKKEMQVT--EAPVTQEAVNGHGALEV-DMALGSPEMDVRKKKKKKNQQLKEPEAA 227
+ GK++ E +T +A VT++AV ++ + + SPE V+ K+ K+ + P+A
Sbjct: 32638 SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA-VKSPKRVKSPEPSHPKAV 32696
Query: 228 GPVGTEPT-VETLEPLGVLFP 247
P T+PT E ++ L V P
Sbjct: 32697 SPTETKPTPTEKVQHLPVSAP 32717
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 61.2 bits (147), Expect = 2e-09
Identities = 83/335 (24%), Positives = 125/335 (37%), Gaps = 59/335 (17%)
Query: 224 PEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTE-PLEDT 282
P+ GP G +P + P + K + +P G T K Q T+ P D
Sbjct: 220 PKQQGP-GRDPLQQDGTPKSISSQQPEKIKSQPPG---------TGKPIQGPTQTPQTDH 269
Query: 283 VLSPTKKRKRQKGTEGMEPEEGVTVE-SQPQVKVEPLEEAIP-LPPTKKRKKEKGQMAMM 340
P ++ + T+ + G +V+ S P P+++ P PP ++ EK Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 341 EPGTEAMEPVEPEMK-------PLESPGGTMAPQQPEG-AKPQAQA-------------- 378
+P + +P + P++ PG T P QP G AKP AQ
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 379 ALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEP-------QAAPTST--------KK 423
ALA P K QQ +P T+ VG P +P PT T K
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 424 KKKKKERGHTVTEPIQPLEP--ELPGEGQPE------ARATPGSTKKRKKQSQESRMPET 475
++ G T + P +P +LPG +P A+ P K SQ+ +
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 476 VPQEEMPGPPLNSESGE-EAPTGRDKKRKQQQQQP 509
PQ+ P P + G + P+ + K QQP
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Score = 50.4 bits (119), Expect = 4e-06
Identities = 85/431 (19%), Positives = 159/431 (36%), Gaps = 43/431 (9%)
Query: 102 GGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGP 161
G G + S + P P P+ +P P PP + + G PP
Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992
Query: 162 RSALAPNLLTSGKKKKEMQVTEAPVTQ--EAVNGHGALEVDMAL-GSPEMDVRKKKKKKN 218
+ +K E + +AP + E ++ +L P+ V K +K+
Sbjct: 993 SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS 1052
Query: 219 QQLKEPEAAGPV-GTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTE 277
+ PE+ P+ TE + + +P F + T+ + + F P +
Sbjct: 1053 PK---PESTCPLCKTELNIGSKDPPN--FNTCTECKNQVCNLCGFNPTPHLTE------- 1100
Query: 278 PLEDTVLSPTKKRKRQKGTEG----MEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKE 333
+++ + + ++ G G M P S V E + +PP K K+
Sbjct: 1101 -IQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 334 KGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQ 393
+ Q E +E V+ + + P Q+ E +K + A A +KK E+++
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 394 DATVEPETEVVGPELPDDLEPQAAPTSTKKK--------KKKKERGHTVTEPIQPLEPEL 445
+ PE E + E L + PT KK ++++ + +Q E +L
Sbjct: 1220 ---LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276
Query: 446 PGEGQPEARATPGSTKKRKKQSQESRMPETVPQE---------EMPGPPLNSESGEEAPT 496
G P+ G + K + S P+++P+E E P PP ++ + P
Sbjct: 1277 EGRVAPKT-VQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP- 1334
Query: 497 GRDKKRKQQQQ 507
G++K K+ +
Sbjct: 1335 GKEKTEKEDDK 1345
Score = 49.3 bits (116), Expect = 8e-06
Identities = 76/323 (23%), Positives = 114/323 (35%), Gaps = 32/323 (9%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGG--NPPVTGPRSALAP-NLLTSGKKKK 177
P Q QP PA PP Q P GL G PPV P + P L K
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQ-PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 178 EMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVE 237
+ +E P +++ G AL +G K QQ+ P+ P+ +P ++
Sbjct: 374 QQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQ 428
Query: 238 TLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTE 297
+ P P+ T ++ GK + +Q PTK + G
Sbjct: 429 S--PAKAPGPTKTPVQQPGPGK---------IPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 298 GMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEP-EMKP 356
P++ + PQ + PP+++ K +PG P +P KP
Sbjct: 478 KPPPQQPGPAKPPPQ------QPGSAKPPSQQPGSTK--PPPQQPGPAKPSPQQPGSTKP 529
Query: 357 LESPGGTMAP--QQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPE-LPDDLE 413
G+ P QQP AKP AQ + + + Q TV P + + LP +
Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTIC 589
Query: 414 PQAAPTSTKKKKKKKERGHTVTE 436
P T +K +T TE
Sbjct: 590 PLCNTTELLLHVPEKANFNTCTE 612
Score = 49.3 bits (116), Expect = 8e-06
Identities = 99/470 (21%), Positives = 158/470 (33%), Gaps = 74/470 (15%)
Query: 97 PSTEAGGGLTCA--SAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGG 154
P+ +AG G T A + P L GP + P QP PA PPPQ P +
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKP---PPQQPGPAKPPPQQPGSAK-------- 498
Query: 155 NPPVTGPRSALAPNLLTSGKKKKEMQ--VTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
PP P S P K Q T+ P Q A + A S + +
Sbjct: 499 -PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF----EPEDKT 268
+ + + +P P +P + L +TT+ K F E +
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 269 VKQEQINTEPLEDTV---LSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP------LE 319
N P V L + KR G + + P V QP++K P +
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD-LAP---VPSSPQPKLKTAPVTTTSAVS 673
Query: 320 EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKP-LESPGGTMAPQQPEG---AKPQ 375
++ P P KK+ + E +P +P L A Q PE +KP
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 376 AQAALAAPKKKTK-----KEKQQDATVEPETEVVG-------PELP-----DDLEPQAAP 418
+ P ++ K + +Q V+P T++V P++P E + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 419 TSTKKKKKKKERGHTVTEPIQPLE------------------PELPGEGQPEARATPGST 460
K + E + P + P +GQ +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 461 KKRKKQSQESRMPETVPQEE-MPGPP-LNSESGEEAPTGRDKKRKQQQQQ 508
+ +K Q++ S P+ P + P PP +G+ PT + + Q+Q +
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Score = 48.9 bits (115), Expect = 1e-05
Identities = 84/425 (19%), Positives = 144/425 (33%), Gaps = 73/425 (17%)
Query: 127 GSPLQPIPASPPPQI---PPGLRPRFCAFGGNPPVTGPRSALAP--NLLTSGKKKKEMQV 181
G L P+P+SP P++ P P T P+ AP +L + + KK +
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 182 TEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEP 241
+ P HG+ A PE D K KEP P +
Sbjct: 707 VKQPTL------HGSPSAK-AKQPPEADSLSKPAPP----KEPSVPSEQDKAPVADD--- 752
Query: 242 LGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEP 301
KPK + +P V T+P D S + + +K T ++
Sbjct: 753 -------------KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKT 797
Query: 302 EEGVTVESQPQV--KVEPLE-EAIPLPPTKKR--------KKEKGQMAMMEPGTEAMEPV 350
+ +S P KV P + +AIP P + + + KGQ ++P + EP
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK-QVDPVQKKEEPK 856
Query: 351 EPEMKPLESPGGTMAPQ---QPEGAKPQAQAALAAPKKKTKKEKQQ--------DATVEP 399
+ + K P P+ P G +P A + P++ K ++Q T P
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 400 ETEVVGPE----------------LPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEP 443
+++ P+ +L A + P QP
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTS 976
Query: 444 ELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRK 503
+ P + +A P + KK+++ + P+ E +E+ ++ P +D K
Sbjct: 977 QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL 1036
Query: 504 QQQQQ 508
+ Q
Sbjct: 1037 TAEPQ 1041
Score = 41.6 bits (96), Expect = 0.002
Identities = 90/427 (21%), Positives = 143/427 (33%), Gaps = 75/427 (17%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEG-PQQSLSGSPLQPIPASPPPQIP-PGLRPRFCAFG 153
AP T + PQ T + P+Q LS +P P PPP + P L A
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKA 720
Query: 154 GNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALE-----VDMALGSPEM 208
PP S AP S +++ +APV + ++ V + + +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 209 DVRKKK------KKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF 262
D+ K +K LK A PT E + P F S R K
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP----FDSKAIPRPASDSKIIS 832
Query: 263 EPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLE--- 319
P + + Q +P++ KK + +K M P+ +++P K P
Sbjct: 833 HPGPSSESKGQKQVDPVQ-------KKEEPKKAQTKMSPKP----DAKPMPKGSPTPPGP 881
Query: 320 -----EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTM---------- 364
+ +P P + +E+ + + G+ P P E+ G +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 365 ------APQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAP 418
QP P +Q+ AP K Q A +P T + P QA P
Sbjct: 942 ASNLISTAGQPG---PHSQSGPGAPMK------QAPAPSQPPTS----QGPPKSTGQAPP 988
Query: 419 TSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKK---QSQESRMPET 475
K KKE E ++P + P + E P K K + Q++ +P
Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 476 VPQEEMP 482
+ + P
Sbjct: 1049 LEKSPKP 1055
Score = 36.2 bits (82), Expect = 0.073
Identities = 60/271 (22%), Positives = 94/271 (34%), Gaps = 28/271 (10%)
Query: 103 GGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPR 162
G + +S P +S P P P PPP PP P PP P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP--------PPPLPPP 2430
Query: 163 SALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLK 222
++ P +L K VT A +AV LE L S + V + +
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVT---TLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 223 EPEAAGPVG------TEPTVETLEPLGVL--FPSTTKK----RKKPKGKETFEPEDKTVK 270
++ P G EP+ + P V+ P+TT+K KP G +
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 271 QEQINTEPLEDTVLSPTKKRKRQKGTEGM-EPEEGVTVESQPQVKVE-PLEEAIPLPPTK 328
P + LSP + + ++ + E +T+ S+P + +AI P
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607
Query: 329 KRKKEKGQMAMMEPGTEAMEPVEPEMKPLES 359
K+ + +EP + PV P+ S
Sbjct: 2608 SPSKD---LVSVEPVFSVVPPVTAVEIPISS 2635
Score = 35.8 bits (81), Expect = 0.095
Identities = 46/192 (23%), Positives = 72/192 (37%), Gaps = 31/192 (16%)
Query: 301 PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP 360
P++ +TV S P PL +A+ T + G + + T A PV P KP P
Sbjct: 2439 PKKKLTVAS-PVTTATPLFDAVTTLETTAVLRSNG-LPVTRICTTAPPPVPP--KPSSIP 2494
Query: 361 GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS 420
G + +PE +KP P+ T +K D +P G L TS
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP----TGLSL----------TS 2540
Query: 421 TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE 480
+ + + P PL P + S+ + K E+ + T+P E
Sbjct: 2541 SMTLNLVTSADYKLPSPTSPLSPH-----------SNKSSPRFSKSLTETYVVITLPSE- 2588
Query: 481 MPGPPLNSESGE 492
PG P +S + +
Sbjct: 2589 -PGTPTDSSASQ 2599
Score = 33.1 bits (74), Expect = 0.62
Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 445 LPGEGQPEARATPGSTKKRKKQSQE----------SRMPETVPQEEMPGPPLNSESGEEA 494
+P E + A P K KKQ QE ++ ET+ E++P + EE+
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198
Query: 495 PTGRDKKRKQQQQQPV 510
+DK Q+++P+
Sbjct: 1199 KLEKDKASALQEKKPL 1214
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 61.2 bits (147), Expect = 2e-09
Identities = 83/335 (24%), Positives = 125/335 (37%), Gaps = 59/335 (17%)
Query: 224 PEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTE-PLEDT 282
P+ GP G +P + P + K + +P G T K Q T+ P D
Sbjct: 220 PKQQGP-GRDPLQQDGTPKSISSQQPEKIKSQPPG---------TGKPIQGPTQTPQTDH 269
Query: 283 VLSPTKKRKRQKGTEGMEPEEGVTVE-SQPQVKVEPLEEAIP-LPPTKKRKKEKGQMAMM 340
P ++ + T+ + G +V+ S P P+++ P PP ++ EK Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 341 EPGTEAMEPVEPEMK-------PLESPGGTMAPQQPEG-AKPQAQA-------------- 378
+P + +P + P++ PG T P QP G AKP AQ
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 379 ALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEP-------QAAPTST--------KK 423
ALA P K QQ +P T+ VG P +P PT T K
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 424 KKKKKERGHTVTEPIQPLEP--ELPGEGQPE------ARATPGSTKKRKKQSQESRMPET 475
++ G T + P +P +LPG +P A+ P K SQ+ +
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 476 VPQEEMPGPPLNSESGE-EAPTGRDKKRKQQQQQP 509
PQ+ P P + G + P+ + K QQP
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Score = 50.4 bits (119), Expect = 4e-06
Identities = 85/431 (19%), Positives = 159/431 (36%), Gaps = 43/431 (9%)
Query: 102 GGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGP 161
G G + S + P P P+ +P P PP + + G PP
Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992
Query: 162 RSALAPNLLTSGKKKKEMQVTEAPVTQ--EAVNGHGALEVDMAL-GSPEMDVRKKKKKKN 218
+ +K E + +AP + E ++ +L P+ V K +K+
Sbjct: 993 SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS 1052
Query: 219 QQLKEPEAAGPV-GTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTE 277
+ PE+ P+ TE + + +P F + T+ + + F P +
Sbjct: 1053 PK---PESTCPLCKTELNIGSKDPPN--FNTCTECKNQVCNLCGFNPTPHLTE------- 1100
Query: 278 PLEDTVLSPTKKRKRQKGTEG----MEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKE 333
+++ + + ++ G G M P S V E + +PP K K+
Sbjct: 1101 -IQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 334 KGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQ 393
+ Q E +E V+ + + P Q+ E +K + A A +KK E+++
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 394 DATVEPETEVVGPELPDDLEPQAAPTSTKKK--------KKKKERGHTVTEPIQPLEPEL 445
+ PE E + E L + PT KK ++++ + +Q E +L
Sbjct: 1220 ---LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276
Query: 446 PGEGQPEARATPGSTKKRKKQSQESRMPETVPQE---------EMPGPPLNSESGEEAPT 496
G P+ G + K + S P+++P+E E P PP ++ + P
Sbjct: 1277 EGRVAPKT-VQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP- 1334
Query: 497 GRDKKRKQQQQ 507
G++K K+ +
Sbjct: 1335 GKEKTEKEDDK 1345
Score = 49.3 bits (116), Expect = 8e-06
Identities = 76/323 (23%), Positives = 114/323 (35%), Gaps = 32/323 (9%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGG--NPPVTGPRSALAP-NLLTSGKKKK 177
P Q QP PA PP Q P GL G PPV P + P L K
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQ-PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 178 EMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVE 237
+ +E P +++ G AL +G K QQ+ P+ P+ +P ++
Sbjct: 374 QQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQ 428
Query: 238 TLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTE 297
+ P P+ T ++ GK + +Q PTK + G
Sbjct: 429 S--PAKAPGPTKTPVQQPGPGK---------IPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 298 GMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEP-EMKP 356
P++ + PQ + PP+++ K +PG P +P KP
Sbjct: 478 KPPPQQPGPAKPPPQ------QPGSAKPPSQQPGSTK--PPPQQPGPAKPSPQQPGSTKP 529
Query: 357 LESPGGTMAP--QQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPE-LPDDLE 413
G+ P QQP AKP AQ + + + Q TV P + + LP +
Sbjct: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTIC 589
Query: 414 PQAAPTSTKKKKKKKERGHTVTE 436
P T +K +T TE
Sbjct: 590 PLCNTTELLLHVPEKANFNTCTE 612
Score = 49.3 bits (116), Expect = 8e-06
Identities = 99/470 (21%), Positives = 158/470 (33%), Gaps = 74/470 (15%)
Query: 97 PSTEAGGGLTCA--SAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGG 154
P+ +AG G T A + P L GP + P QP PA PPPQ P +
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKP---PPQQPGPAKPPPQQPGSAK-------- 498
Query: 155 NPPVTGPRSALAPNLLTSGKKKKEMQ--VTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
PP P S P K Q T+ P Q A + A S + +
Sbjct: 499 -PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF----EPEDKT 268
+ + + +P P +P + L +TT+ K F E +
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 269 VKQEQINTEPLEDTV---LSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP------LE 319
N P V L + KR G + + P V QP++K P +
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD-LAP---VPSSPQPKLKTAPVTTTSAVS 673
Query: 320 EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKP-LESPGGTMAPQQPEG---AKPQ 375
++ P P KK+ + E +P +P L A Q PE +KP
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 376 AQAALAAPKKKTK-----KEKQQDATVEPETEVVG-------PELP-----DDLEPQAAP 418
+ P ++ K + +Q V+P T++V P++P E + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 419 TSTKKKKKKKERGHTVTEPIQPLE------------------PELPGEGQPEARATPGST 460
K + E + P + P +GQ +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 461 KKRKKQSQESRMPETVPQEE-MPGPP-LNSESGEEAPTGRDKKRKQQQQQ 508
+ +K Q++ S P+ P + P PP +G+ PT + + Q+Q +
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Score = 48.9 bits (115), Expect = 1e-05
Identities = 84/425 (19%), Positives = 144/425 (33%), Gaps = 73/425 (17%)
Query: 127 GSPLQPIPASPPPQI---PPGLRPRFCAFGGNPPVTGPRSALAP--NLLTSGKKKKEMQV 181
G L P+P+SP P++ P P T P+ AP +L + + KK +
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 182 TEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEP 241
+ P HG+ A PE D K KEP P +
Sbjct: 707 VKQPTL------HGSPSAK-AKQPPEADSLSKPAPP----KEPSVPSEQDKAPVADD--- 752
Query: 242 LGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEP 301
KPK + +P V T+P D S + + +K T ++
Sbjct: 753 -------------KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKT 797
Query: 302 EEGVTVESQPQV--KVEPLE-EAIPLPPTKKR--------KKEKGQMAMMEPGTEAMEPV 350
+ +S P KV P + +AIP P + + + KGQ ++P + EP
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK-QVDPVQKKEEPK 856
Query: 351 EPEMKPLESPGGTMAPQ---QPEGAKPQAQAALAAPKKKTKKEKQQ--------DATVEP 399
+ + K P P+ P G +P A + P++ K ++Q T P
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 400 ETEVVGPE----------------LPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEP 443
+++ P+ +L A + P QP
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTS 976
Query: 444 ELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRK 503
+ P + +A P + KK+++ + P+ E +E+ ++ P +D K
Sbjct: 977 QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL 1036
Query: 504 QQQQQ 508
+ Q
Sbjct: 1037 TAEPQ 1041
Score = 41.6 bits (96), Expect = 0.002
Identities = 90/427 (21%), Positives = 143/427 (33%), Gaps = 75/427 (17%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEG-PQQSLSGSPLQPIPASPPPQIP-PGLRPRFCAFG 153
AP T + PQ T + P+Q LS +P P PPP + P L A
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKA 720
Query: 154 GNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALE-----VDMALGSPEM 208
PP S AP S +++ +APV + ++ V + + +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 209 DVRKKK------KKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETF 262
D+ K +K LK A PT E + P F S R K
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP----FDSKAIPRPASDSKIIS 832
Query: 263 EPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLE--- 319
P + + Q +P++ KK + +K M P+ +++P K P
Sbjct: 833 HPGPSSESKGQKQVDPVQ-------KKEEPKKAQTKMSPKP----DAKPMPKGSPTPPGP 881
Query: 320 -----EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTM---------- 364
+ +P P + +E+ + + G+ P P E+ G +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 365 ------APQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAP 418
QP P +Q+ AP K Q A +P T + P QA P
Sbjct: 942 ASNLISTAGQPG---PHSQSGPGAPMK------QAPAPSQPPTS----QGPPKSTGQAPP 988
Query: 419 TSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKK---QSQESRMPET 475
K KKE E ++P + P + E P K K + Q++ +P
Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 476 VPQEEMP 482
+ + P
Sbjct: 1049 LEKSPKP 1055
Score = 36.2 bits (82), Expect = 0.073
Identities = 60/271 (22%), Positives = 94/271 (34%), Gaps = 28/271 (10%)
Query: 103 GGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPR 162
G + +S P +S P P P PPP PP P PP P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP--------PPPLPPP 2430
Query: 163 SALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLK 222
++ P +L K VT A +AV LE L S + V + +
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVT---TLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 223 EPEAAGPVG------TEPTVETLEPLGVL--FPSTTKK----RKKPKGKETFEPEDKTVK 270
++ P G EP+ + P V+ P+TT+K KP G +
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 271 QEQINTEPLEDTVLSPTKKRKRQKGTEGM-EPEEGVTVESQPQVKVE-PLEEAIPLPPTK 328
P + LSP + + ++ + E +T+ S+P + +AI P
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607
Query: 329 KRKKEKGQMAMMEPGTEAMEPVEPEMKPLES 359
K+ + +EP + PV P+ S
Sbjct: 2608 SPSKD---LVSVEPVFSVVPPVTAVEIPISS 2635
Score = 35.8 bits (81), Expect = 0.095
Identities = 46/192 (23%), Positives = 72/192 (37%), Gaps = 31/192 (16%)
Query: 301 PEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESP 360
P++ +TV S P PL +A+ T + G + + T A PV P KP P
Sbjct: 2439 PKKKLTVAS-PVTTATPLFDAVTTLETTAVLRSNG-LPVTRICTTAPPPVPP--KPSSIP 2494
Query: 361 GGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTS 420
G + +PE +KP P+ T +K D +P G L TS
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP----TGLSL----------TS 2540
Query: 421 TKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEE 480
+ + + P PL P + S+ + K E+ + T+P E
Sbjct: 2541 SMTLNLVTSADYKLPSPTSPLSPH-----------SNKSSPRFSKSLTETYVVITLPSE- 2588
Query: 481 MPGPPLNSESGE 492
PG P +S + +
Sbjct: 2589 -PGTPTDSSASQ 2599
Score = 33.1 bits (74), Expect = 0.62
Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 445 LPGEGQPEARATPGSTKKRKKQSQE----------SRMPETVPQEEMPGPPLNSESGEEA 494
+P E + A P K KKQ QE ++ ET+ E++P + EE+
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198
Query: 495 PTGRDKKRKQQQQQPV 510
+DK Q+++P+
Sbjct: 1199 KLEKDKASALQEKKPL 1214
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 60.1 bits (144), Expect = 5e-09
Identities = 85/351 (24%), Positives = 135/351 (38%), Gaps = 49/351 (13%)
Query: 118 LEGPQQSLSGSPLQP-IPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKK 176
LEG L P + + A PPP+ P R R GG P +A P T K K
Sbjct: 38 LEGFLSELEPEPREDDVEAPPPPEPTP--RVRKAQAGGKPGKRPGTAAEVPPEKTKDKGK 95
Query: 177 KEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTV 236
K + V +E++ G P +K K+K + K+P+ P T+
Sbjct: 96 KGKKDKGPKVPKESLEG-SPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPK 154
Query: 237 ETLEPLGVLFPSTTKKRKKPKGKETFE---PEDKTVKQEQINTE---PLEDTVLSPTKKR 290
E P P + K+ ET E P + E++ E PL + +P ++
Sbjct: 155 EK-PPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEET 213
Query: 291 KRQKGTEGMEPEEGV---TVESQPQVKVEPLEEAIPL--------PPTKKRKKEKGQMAM 339
+ EPEE T++ Q++ E E+ + PP+++R+ E+
Sbjct: 214 HVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEP 273
Query: 340 ME---PGTEAMEPVEPEMKPLESP------GGTMAPQQ---------PEGAKPQAQAALA 381
E P E +EP +KPL P G + P P KP A+
Sbjct: 274 PEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTD 333
Query: 382 APKKKTKKEKQQDATVEPETEVVG---------PELPDDLEPQAAPTSTKK 423
K++ KK K++D++ + ET+ P ++LE + PT K
Sbjct: 334 EEKEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTEKVK 384
Score = 50.4 bits (119), Expect = 4e-06
Identities = 59/223 (26%), Positives = 89/223 (39%), Gaps = 21/223 (9%)
Query: 303 EGVTVESQPQVKVEPLEEAIPLPPTKK-RKKEKGQMAMMEPGTEAMEPVEPEM----KPL 357
EG E +P+ + + +E P PT + RK + G PGT A P E K
Sbjct: 39 EGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGK 98
Query: 358 ESPGGTMAPQQPEGAKPQAQAALAAPKKKTKK--EKQQDATVEPETEVVGPELPDDLEPQ 415
+ G + + EG+ + P K TKK EK AT +P+ + P +
Sbjct: 99 KDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEK---PPKATKKPKE 155
Query: 416 AAPTSTKKKKKKKER-----GHTVTEPIQPLEPELPG-EGQPEARATPGSTKKRKKQSQ- 468
P +TKK K T+ P+ P P PG E P+ P S + +
Sbjct: 156 KPPKATKKPPSGKRPPILAPSETLEWPLPP--PPSPGPEELPQEGGAPLSNNWQNPGEET 213
Query: 469 --ESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQQQQP 509
E+R + P+EE P L+ E D + ++Q+QP
Sbjct: 214 HVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQP 256
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 16/149 (10%)
Query: 362 GTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTST 421
G ++ +PE + +A P + T + ++ A +P P ++ P+ T
Sbjct: 40 GFLSELEPEPREDDVEAP--PPPEPTPRVRKAQAGGKPGKR---PGTAAEVPPEK--TKD 92
Query: 422 KKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEM 481
K KK KK++G V + P P +G+ + P +TKK K++ P ++
Sbjct: 93 KGKKGKKDKGPKVPKESLEGSPRPPKKGKEKP---PKATKKPKEK------PPKATKKPK 143
Query: 482 PGPPLNSESGEEAPTGRDKKRKQQQQQPV 510
PP ++ +E P KK ++ P+
Sbjct: 144 EKPPKATKKPKEKPPKATKKPPSGKRPPI 172
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/421 (23%), Positives = 136/421 (32%), Gaps = 39/421 (9%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPAS--PPPQIPPGLRPRFCAFG 153
A +T G LT P T P++ S +P +P P + P P P
Sbjct: 201 AETTTKGPALTTPKEPTPTT-----PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 154 GNPPVT-GPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
P P + P T + AP T ++ P K
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 315
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQE 272
+ KEP P PT + P P+ T KKP EP T K+
Sbjct: 316 EPAPTTP--KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEP 372
Query: 273 QINT--EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP----LEEAIPLPP 326
T EP T P + T EP T +S P EP +E P P
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTP 431
Query: 327 TKKRKKEKGQMAMMEPGTEA-MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKK 385
+ + A P A P EP + P T P++P P+ + A PKK
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPK-ETAPTTPKK 489
Query: 386 KTKKEKQQDATVEPET------EVVGPELPDDLEP----QAAPTSTKKKKKKKERGHTVT 435
T ++ A PE E + P P++ P + APT+ K + T
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 436 EPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAP 495
P +P P P E P +T K + T +E P P E AP
Sbjct: 550 TPKEP-APTTPKEPAP-------TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 496 T 496
T
Sbjct: 602 T 602
Score = 57.0 bits (136), Expect = 4e-08
Identities = 80/321 (24%), Positives = 101/321 (31%), Gaps = 45/321 (14%)
Query: 225 EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDT-- 282
E + V E TVET E +TT K+ GKE +T E+ + + L T
Sbjct: 139 ETSLTVNKETTVETKET------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 283 -VLSPTKKR------------KRQKGTEGMEPEEGVTVESQPQ-VKVEPLEEAIPLPPTK 328
+ PT K K T EP E P +K P P P T
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 329 KRK----KEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
K KE EP P EP + P T P K A P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEP------QAAPTSTKKKKKKKERGHTVTEPI 438
T KE EP P EP + APT+ KK + T P
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 439 QPL-------EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMP---GPPLNS 488
+P P P E P + +T K + P T P+E P P +
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-TTPKEPSPTTTKEPAPT 429
Query: 489 ESGEEAPTGRDKKRKQQQQQP 509
E APT K ++P
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEP 450
Score = 48.1 bits (113), Expect = 2e-05
Identities = 85/393 (21%), Positives = 123/393 (31%), Gaps = 47/393 (11%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSAL--APNLLTSGKKKKE 178
P++ +P +P P +P P + P T P+ P LT +K
Sbjct: 439 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 179 MQVTE---APVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP-VGTEP 234
T AP T E ++A +PE ++ P+AA P EP
Sbjct: 499 APTTPEKPAPTTPE----------ELAPTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEP 546
Query: 235 TVET-LEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKR--- 290
T EP P+T K+ KET K + EP T P K
Sbjct: 547 APTTPKEPA----PTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 601
Query: 291 ---KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPG-TEA 346
K T +P + P EP P P K + EP T
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTP 660
Query: 347 MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGP 406
+P E+ P + G T + A PK+ ++ A PET
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP---- 716
Query: 407 ELPDDLEPQAAPTSTKK-----KKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTK 461
P + PT+TK+ K + EP P E TP +TK
Sbjct: 717 --PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 774
Query: 462 KRKKQSQESRMPE----TVPQEEMPGPPLNSES 490
+ + + E T P+ P + E+
Sbjct: 775 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 807
Score = 44.3 bits (103), Expect = 3e-04
Identities = 95/411 (23%), Positives = 148/411 (36%), Gaps = 67/411 (16%)
Query: 95 LAPST-EAGGGLTC----ASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLR--- 146
LAP+T + TC + P+GT P++ +P +P P +P P L+
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656
Query: 147 ---PRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVT-QEAVNGHGALEVDMA 202
P+ A P P + P TS K AP T +E
Sbjct: 657 PTTPKKPA----PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 712
Query: 203 LGSP-----EMDVRKKKKKKNQQLKEPEAAGP-VGTEPTVETLE--PLGVLFPSTTKKRK 254
+P E+ K+ K P+ + P + EPT + LE P P TTK
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP-TTKTPA 771
Query: 255 KPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK 314
K + T +DKT +++ + T P E T +P K ++ T + E + QV
Sbjct: 772 ATKPEMTTTAKDKTTERD-LRTTP-ETTTAAP--KMTKETATTTEKTTESKITATTTQVT 827
Query: 315 VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKP 374
++ P T + T + E KP E+ +P+
Sbjct: 828 STTTQDTTPFKITTLKTTTLAPKVTTTKKT--ITTTEIMNKPEETA-------KPKDRAT 878
Query: 375 QAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTV 434
++A P+K TK K+ +T +P+T +P +P+ PT K T
Sbjct: 879 NSKATTPKPQKPTKAPKKPTSTKKPKT------MPRVRKPKTTPTPRKM---------TS 923
Query: 435 TEPIQPLEPELPGEGQPEARATPG--STKKRKKQSQESRMPETVPQEEMPG 483
T P E P +R T R Q+ S++ E P+ E G
Sbjct: 924 TMP----------ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 964
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/421 (23%), Positives = 136/421 (32%), Gaps = 39/421 (9%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPAS--PPPQIPPGLRPRFCAFG 153
A +T G LT P T P++ S +P +P P + P P P
Sbjct: 242 AETTTKGPALTTPKEPTPTT-----PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 154 GNPPVT-GPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
P P + P T + AP T ++ P K
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 356
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQE 272
+ KEP P PT + P P+ T KKP EP T K+
Sbjct: 357 EPAPTTP--KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEP 413
Query: 273 QINT--EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP----LEEAIPLPP 326
T EP T P + T EP T +S P EP +E P P
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTP 472
Query: 327 TKKRKKEKGQMAMMEPGTEA-MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKK 385
+ + A P A P EP + P T P++P P+ + A PKK
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPK-ETAPTTPKK 530
Query: 386 KTKKEKQQDATVEPET------EVVGPELPDDLEP----QAAPTSTKKKKKKKERGHTVT 435
T ++ A PE E + P P++ P + APT+ K + T
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 436 EPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAP 495
P +P P P E P +T K + T +E P P E AP
Sbjct: 591 TPKEP-APTTPKEPAP-------TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 496 T 496
T
Sbjct: 643 T 643
Score = 57.0 bits (136), Expect = 4e-08
Identities = 80/321 (24%), Positives = 101/321 (31%), Gaps = 45/321 (14%)
Query: 225 EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDT-- 282
E + V E TVET E +TT K+ GKE +T E+ + + L T
Sbjct: 180 ETSLTVNKETTVETKET------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 283 -VLSPTKKR------------KRQKGTEGMEPEEGVTVESQPQ-VKVEPLEEAIPLPPTK 328
+ PT K K T EP E P +K P P P T
Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 329 KRK----KEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
K KE EP P EP + P T P K A P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEP------QAAPTSTKKKKKKKERGHTVTEPI 438
T KE EP P EP + APT+ KK + T P
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 439 QPL-------EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMP---GPPLNS 488
+P P P E P + +T K + P T P+E P P +
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-TTPKEPSPTTTKEPAPT 470
Query: 489 ESGEEAPTGRDKKRKQQQQQP 509
E APT K ++P
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEP 491
Score = 48.1 bits (113), Expect = 2e-05
Identities = 85/393 (21%), Positives = 123/393 (31%), Gaps = 47/393 (11%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSAL--APNLLTSGKKKKE 178
P++ +P +P P +P P + P T P+ P LT +K
Sbjct: 480 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 179 MQVTE---APVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP-VGTEP 234
T AP T E ++A +PE ++ P+AA P EP
Sbjct: 540 APTTPEKPAPTTPE----------ELAPTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEP 587
Query: 235 TVET-LEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKR--- 290
T EP P+T K+ KET K + EP T P K
Sbjct: 588 APTTPKEPA----PTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 642
Query: 291 ---KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPG-TEA 346
K T +P + P EP P P K + EP T
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTP 701
Query: 347 MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGP 406
+P E+ P + G T + A PK+ ++ A PET
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP---- 757
Query: 407 ELPDDLEPQAAPTSTKK-----KKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTK 461
P + PT+TK+ K + EP P E TP +TK
Sbjct: 758 --PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 815
Query: 462 KRKKQSQESRMPE----TVPQEEMPGPPLNSES 490
+ + + E T P+ P + E+
Sbjct: 816 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 848
Score = 44.3 bits (103), Expect = 3e-04
Identities = 95/411 (23%), Positives = 148/411 (36%), Gaps = 67/411 (16%)
Query: 95 LAPST-EAGGGLTC----ASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLR--- 146
LAP+T + TC + P+GT P++ +P +P P +P P L+
Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697
Query: 147 ---PRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVT-QEAVNGHGALEVDMA 202
P+ A P P + P TS K AP T +E
Sbjct: 698 PTTPKKPA----PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 753
Query: 203 LGSP-----EMDVRKKKKKKNQQLKEPEAAGP-VGTEPTVETLE--PLGVLFPSTTKKRK 254
+P E+ K+ K P+ + P + EPT + LE P P TTK
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP-TTKTPA 812
Query: 255 KPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK 314
K + T +DKT +++ + T P E T +P K ++ T + E + QV
Sbjct: 813 ATKPEMTTTAKDKTTERD-LRTTP-ETTTAAP--KMTKETATTTEKTTESKITATTTQVT 868
Query: 315 VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKP 374
++ P T + T + E KP E+ +P+
Sbjct: 869 STTTQDTTPFKITTLKTTTLAPKVTTTKKT--ITTTEIMNKPEETA-------KPKDRAT 919
Query: 375 QAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTV 434
++A P+K TK K+ +T +P+T +P +P+ PT K T
Sbjct: 920 NSKATTPKPQKPTKAPKKPTSTKKPKT------MPRVRKPKTTPTPRKM---------TS 964
Query: 435 TEPIQPLEPELPGEGQPEARATPG--STKKRKKQSQESRMPETVPQEEMPG 483
T P E P +R T R Q+ S++ E P+ E G
Sbjct: 965 TMP----------ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 1005
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/421 (23%), Positives = 136/421 (32%), Gaps = 39/421 (9%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPAS--PPPQIPPGLRPRFCAFG 153
A +T G LT P T P++ S +P +P P + P P P
Sbjct: 294 AETTTKGPALTTPKEPTPTT-----PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 154 GNPPVT-GPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
P P + P T + AP T ++ P K
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQE 272
+ KEP P PT + P P+ T KKP EP T K+
Sbjct: 409 EPAPTTP--KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEP 465
Query: 273 QINT--EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP----LEEAIPLPP 326
T EP T P + T EP T +S P EP +E P P
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 327 TKKRKKEKGQMAMMEPGTEA-MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKK 385
+ + A P A P EP + P T P++P P+ + A PKK
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPK-ETAPTTPKK 582
Query: 386 KTKKEKQQDATVEPET------EVVGPELPDDLEP----QAAPTSTKKKKKKKERGHTVT 435
T ++ A PE E + P P++ P + APT+ K + T
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 642
Query: 436 EPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAP 495
P +P P P E P +T K + T +E P P E AP
Sbjct: 643 TPKEP-APTTPKEPAP-------TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 496 T 496
T
Sbjct: 695 T 695
Score = 57.0 bits (136), Expect = 4e-08
Identities = 80/321 (24%), Positives = 101/321 (31%), Gaps = 45/321 (14%)
Query: 225 EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDT-- 282
E + V E TVET E +TT K+ GKE +T E+ + + L T
Sbjct: 232 ETSLTVNKETTVETKET------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285
Query: 283 -VLSPTKKR------------KRQKGTEGMEPEEGVTVESQPQ-VKVEPLEEAIPLPPTK 328
+ PT K K T EP E P +K P P P T
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 329 KRK----KEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
K KE EP P EP + P T P K A P
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEP------QAAPTSTKKKKKKKERGHTVTEPI 438
T KE EP P EP + APT+ KK + T P
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 439 QPL-------EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMP---GPPLNS 488
+P P P E P + +T K + P T P+E P P +
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-TTPKEPSPTTTKEPAPT 522
Query: 489 ESGEEAPTGRDKKRKQQQQQP 509
E APT K ++P
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEP 543
Score = 48.1 bits (113), Expect = 2e-05
Identities = 85/393 (21%), Positives = 123/393 (31%), Gaps = 47/393 (11%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSAL--APNLLTSGKKKKE 178
P++ +P +P P +P P + P T P+ P LT +K
Sbjct: 532 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 179 MQVTE---APVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP-VGTEP 234
T AP T E ++A +PE ++ P+AA P EP
Sbjct: 592 APTTPEKPAPTTPE----------ELAPTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEP 639
Query: 235 TVET-LEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKR--- 290
T EP P+T K+ KET K + EP T P K
Sbjct: 640 APTTPKEPA----PTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 694
Query: 291 ---KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPG-TEA 346
K T +P + P EP P P K + EP T
Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTP 753
Query: 347 MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGP 406
+P E+ P + G T + A PK+ ++ A PET
Sbjct: 754 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP---- 809
Query: 407 ELPDDLEPQAAPTSTKK-----KKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTK 461
P + PT+TK+ K + EP P E TP +TK
Sbjct: 810 --PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 867
Query: 462 KRKKQSQESRMPE----TVPQEEMPGPPLNSES 490
+ + + E T P+ P + E+
Sbjct: 868 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 900
Score = 44.3 bits (103), Expect = 3e-04
Identities = 95/411 (23%), Positives = 148/411 (36%), Gaps = 67/411 (16%)
Query: 95 LAPST-EAGGGLTC----ASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLR--- 146
LAP+T + TC + P+GT P++ +P +P P +P P L+
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 147 ---PRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVT-QEAVNGHGALEVDMA 202
P+ A P P + P TS K AP T +E
Sbjct: 750 PTTPKKPA----PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 805
Query: 203 LGSP-----EMDVRKKKKKKNQQLKEPEAAGP-VGTEPTVETLE--PLGVLFPSTTKKRK 254
+P E+ K+ K P+ + P + EPT + LE P P TTK
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP-TTKTPA 864
Query: 255 KPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK 314
K + T +DKT +++ + T P E T +P K ++ T + E + QV
Sbjct: 865 ATKPEMTTTAKDKTTERD-LRTTP-ETTTAAP--KMTKETATTTEKTTESKITATTTQVT 920
Query: 315 VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKP 374
++ P T + T + E KP E+ +P+
Sbjct: 921 STTTQDTTPFKITTLKTTTLAPKVTTTKKT--ITTTEIMNKPEETA-------KPKDRAT 971
Query: 375 QAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTV 434
++A P+K TK K+ +T +P+T +P +P+ PT K T
Sbjct: 972 NSKATTPKPQKPTKAPKKPTSTKKPKT------MPRVRKPKTTPTPRKM---------TS 1016
Query: 435 TEPIQPLEPELPGEGQPEARATPG--STKKRKKQSQESRMPETVPQEEMPG 483
T P E P +R T R Q+ S++ E P+ E G
Sbjct: 1017 TMP----------ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 1057
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/421 (23%), Positives = 136/421 (32%), Gaps = 39/421 (9%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPAS--PPPQIPPGLRPRFCAFG 153
A +T G LT P T P++ S +P +P P + P P P
Sbjct: 335 AETTTKGPALTTPKEPTPTT-----PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 154 GNPPVT-GPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRK 212
P P + P T + AP T ++ P K
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 213 KKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQE 272
+ KEP P PT + P P+ T KKP EP T K+
Sbjct: 450 EPAPTTP--KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEP 506
Query: 273 QINT--EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEP----LEEAIPLPP 326
T EP T P + T EP T +S P EP +E P P
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 327 TKKRKKEKGQMAMMEPGTEA-MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKK 385
+ + A P A P EP + P T P++P P+ + A PKK
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPK-ETAPTTPKK 623
Query: 386 KTKKEKQQDATVEPET------EVVGPELPDDLEP----QAAPTSTKKKKKKKERGHTVT 435
T ++ A PE E + P P++ P + APT+ K + T
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 683
Query: 436 EPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAP 495
P +P P P E P +T K + T +E P P E AP
Sbjct: 684 TPKEP-APTTPKEPAP-------TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 496 T 496
T
Sbjct: 736 T 736
Score = 57.0 bits (136), Expect = 4e-08
Identities = 80/321 (24%), Positives = 101/321 (31%), Gaps = 45/321 (14%)
Query: 225 EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDT-- 282
E + V E TVET E +TT K+ GKE +T E+ + + L T
Sbjct: 273 ETSLTVNKETTVETKET------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326
Query: 283 -VLSPTKKR------------KRQKGTEGMEPEEGVTVESQPQ-VKVEPLEEAIPLPPTK 328
+ PT K K T EP E P +K P P P T
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 329 KRK----KEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
K KE EP P EP + P T P K A P
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEP------QAAPTSTKKKKKKKERGHTVTEPI 438
T KE EP P EP + APT+ KK + T P
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 439 QPL-------EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMP---GPPLNS 488
+P P P E P + +T K + P T P+E P P +
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-TTPKEPSPTTTKEPAPT 563
Query: 489 ESGEEAPTGRDKKRKQQQQQP 509
E APT K ++P
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEP 584
Score = 48.1 bits (113), Expect = 2e-05
Identities = 85/393 (21%), Positives = 123/393 (31%), Gaps = 47/393 (11%)
Query: 121 PQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSAL--APNLLTSGKKKKE 178
P++ +P +P P +P P + P T P+ P LT +K
Sbjct: 573 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 179 MQVTE---APVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP-VGTEP 234
T AP T E ++A +PE ++ P+AA P EP
Sbjct: 633 APTTPEKPAPTTPE----------ELAPTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEP 680
Query: 235 TVET-LEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKR--- 290
T EP P+T K+ KET K + EP T P K
Sbjct: 681 APTTPKEPA----PTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 735
Query: 291 ---KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPG-TEA 346
K T +P + P EP P P K + EP T
Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTP 794
Query: 347 MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGP 406
+P E+ P + G T + A PK+ ++ A PET
Sbjct: 795 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP---- 850
Query: 407 ELPDDLEPQAAPTSTKK-----KKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTK 461
P + PT+TK+ K + EP P E TP +TK
Sbjct: 851 --PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 908
Query: 462 KRKKQSQESRMPE----TVPQEEMPGPPLNSES 490
+ + + E T P+ P + E+
Sbjct: 909 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 941
Score = 44.3 bits (103), Expect = 3e-04
Identities = 95/411 (23%), Positives = 148/411 (36%), Gaps = 67/411 (16%)
Query: 95 LAPST-EAGGGLTC----ASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLR--- 146
LAP+T + TC + P+GT P++ +P +P P +P P L+
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 147 ---PRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVT-QEAVNGHGALEVDMA 202
P+ A P P + P TS K AP T +E
Sbjct: 791 PTTPKKPA----PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 846
Query: 203 LGSP-----EMDVRKKKKKKNQQLKEPEAAGP-VGTEPTVETLE--PLGVLFPSTTKKRK 254
+P E+ K+ K P+ + P + EPT + LE P P TTK
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP-TTKTPA 905
Query: 255 KPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK 314
K + T +DKT +++ + T P E T +P K ++ T + E + QV
Sbjct: 906 ATKPEMTTTAKDKTTERD-LRTTP-ETTTAAP--KMTKETATTTEKTTESKITATTTQVT 961
Query: 315 VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKP 374
++ P T + T + E KP E+ +P+
Sbjct: 962 STTTQDTTPFKITTLKTTTLAPKVTTTKKT--ITTTEIMNKPEETA-------KPKDRAT 1012
Query: 375 QAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTV 434
++A P+K TK K+ +T +P+T +P +P+ PT K T
Sbjct: 1013 NSKATTPKPQKPTKAPKKPTSTKKPKT------MPRVRKPKTTPTPRKM---------TS 1057
Query: 435 TEPIQPLEPELPGEGQPEARATPG--STKKRKKQSQESRMPETVPQEEMPG 483
T P E P +R T R Q+ S++ E P+ E G
Sbjct: 1058 TMP----------ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 1098
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/210 (23%), Positives = 77/210 (36%), Gaps = 17/210 (8%)
Query: 289 KRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAME 348
K K +K EEG ES+PQ EP E + + K + E A +
Sbjct: 20 KEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAK 79
Query: 349 PVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPEL 408
P+ +P ++ G A +P A Q QAA P + K +A P
Sbjct: 80 EEAPKAEPEKTEGAAEAKAEPPKAPEQEQAA-PGPAAGGEAPKAAEAAAAP--------- 129
Query: 409 PDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTK---KRKK 465
AAP + ++ K++ P P E +G P + + PGS++ K+
Sbjct: 130 ----AESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKE 185
Query: 466 QSQESRMPETVPQEEMPGPPLNSESGEEAP 495
+ P + P+ + P EAP
Sbjct: 186 TPAATEAPSSTPKAQGPAASAEEPKPVEAP 215
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 57.0 bits (136), Expect = 4e-08
Identities = 128/583 (21%), Positives = 201/583 (34%), Gaps = 111/583 (19%)
Query: 12 FSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRHVPLSGSQIVKG 71
FS P P+ F P + +Q+ A P HV +GSQ++
Sbjct: 33 FSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG--PAAHVYPAGSQVMMI 90
Query: 72 KLAGKRHRYRVLSSCPQAGEATLLAPSTE-----------AGGGLTCASAPQGTLRILEG 120
+ P G +T + P+ + G T G +G
Sbjct: 91 PSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQG 150
Query: 121 PQQSLSGSPLQPIPASPPPQIPPG-----LRPRFCAFGGNPP----VTGPRSALAPNLLT 171
QQ +G P+ + PPQI P +R R GG ++G R+A P
Sbjct: 151 VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQ 210
Query: 172 SGKKKKEMQVTEAPVTQEAVN----GHGALEVDM-ALGSPEMDVRKKKKKKNQQLKEPEA 226
+G + E P V GA+ D L PE + + P
Sbjct: 211 TGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSP 270
Query: 227 AGPVGTEPTVETLEPLGVLFPST--TKKRKKPKGKETFEPE------------------- 265
G+EP + L G + + + P +ET EP
Sbjct: 271 VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT 330
Query: 266 -DKTVKQEQINTEPLE--DTVLSPTKKRKRQKG---TEGMEPEEGVTVESQPQVKVEPL- 318
K V + + ++ PL+ + S T + G +E +EPE VES P++ P
Sbjct: 331 LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE----VESSPELAPPPAC 386
Query: 319 --EEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQA 376
E +P+ PT + +E A P + EPE + E +MAP A P
Sbjct: 387 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTA-SMAPPTIPSATPAT 444
Query: 377 QAALAAPKKKTKKEKQQD-------ATVEPETEVVGPE-LPDDLEP-------------- 414
+ +P ++ + E++++ E E+E G E LP + P
Sbjct: 445 APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAA 504
Query: 415 -QAAPTSTKKKKK-----KKERGHTVTEPIQPLEPELPG-EGQPEARATPGSTKKRKKQS 467
Q A + K+++K KKE + + + P +P E QP A + PG
Sbjct: 505 TQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--------- 555
Query: 468 QESRMPETVPQEEMPG-PPLNSESGEEAPTGRDKKRKQQQQQP 509
P+ E G PP E+ E + DK + QP
Sbjct: 556 ---------PESEGSGVPPRPEEADETWDSKEDKIHNAENIQP 589
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 57.0 bits (136), Expect = 4e-08
Identities = 128/583 (21%), Positives = 201/583 (34%), Gaps = 111/583 (19%)
Query: 12 FSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRHVPLSGSQIVKG 71
FS P P+ F P + +Q+ A P HV +GSQ++
Sbjct: 33 FSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG--PAAHVYPAGSQVMMI 90
Query: 72 KLAGKRHRYRVLSSCPQAGEATLLAPSTE-----------AGGGLTCASAPQGTLRILEG 120
+ P G +T + P+ + G T G +G
Sbjct: 91 PSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQG 150
Query: 121 PQQSLSGSPLQPIPASPPPQIPPG-----LRPRFCAFGGNPP----VTGPRSALAPNLLT 171
QQ +G P+ + PPQI P +R R GG ++G R+A P
Sbjct: 151 VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQ 210
Query: 172 SGKKKKEMQVTEAPVTQEAVN----GHGALEVDM-ALGSPEMDVRKKKKKKNQQLKEPEA 226
+G + E P V GA+ D L PE + + P
Sbjct: 211 TGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSP 270
Query: 227 AGPVGTEPTVETLEPLGVLFPST--TKKRKKPKGKETFEPE------------------- 265
G+EP + L G + + + P +ET EP
Sbjct: 271 VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT 330
Query: 266 -DKTVKQEQINTEPLE--DTVLSPTKKRKRQKG---TEGMEPEEGVTVESQPQVKVEPL- 318
K V + + ++ PL+ + S T + G +E +EPE VES P++ P
Sbjct: 331 LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE----VESSPELAPPPAC 386
Query: 319 --EEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQA 376
E +P+ PT + +E A P + EPE + E +MAP A P
Sbjct: 387 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTA-SMAPPTIPSATPAT 444
Query: 377 QAALAAPKKKTKKEKQQD-------ATVEPETEVVGPE-LPDDLEP-------------- 414
+ +P ++ + E++++ E E+E G E LP + P
Sbjct: 445 APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAA 504
Query: 415 -QAAPTSTKKKKK-----KKERGHTVTEPIQPLEPELPG-EGQPEARATPGSTKKRKKQS 467
Q A + K+++K KKE + + + P +P E QP A + PG
Sbjct: 505 TQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--------- 555
Query: 468 QESRMPETVPQEEMPG-PPLNSESGEEAPTGRDKKRKQQQQQP 509
P+ E G PP E+ E + DK + QP
Sbjct: 556 ---------PESEGSGVPPRPEEADETWDSKEDKIHNAENIQP 589
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 56.6 bits (135), Expect = 5e-08
Identities = 112/488 (22%), Positives = 173/488 (35%), Gaps = 98/488 (20%)
Query: 96 APSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPG-----LRPRFC 150
AP G T G +G QQ +G P+ + PPQI P +R R
Sbjct: 39 APGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 98
Query: 151 AFGGNPP----VTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVN----GHGALEVDM- 201
GG ++G R+A P +G + E P V GA+ D
Sbjct: 99 NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRP 158
Query: 202 ALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPST--TKKRKKPKGK 259
L PE + + P G+EP + L G + + + P +
Sbjct: 159 GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 218
Query: 260 ETFEPE--------------------DKTVKQEQINTEPLE--DTVLSPTKKRKRQKG-- 295
ET EP K V + + ++ PL+ + S T + G
Sbjct: 219 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 278
Query: 296 -TEGMEPEEGVTVESQPQVKVEPL---EEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVE 351
+E +EPE VES P++ P E +P+ PT + +E A P + E
Sbjct: 279 PSEDLEPE----VESSPELAPPPACPSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSE 333
Query: 352 PEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQD-------ATVEPETEVV 404
PE + E +MAP A P + +P ++ + E++++ E E+E
Sbjct: 334 PEEQAKEVTA-SMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKG 392
Query: 405 GPE-LPDDLEP---------------QAAPTSTKKKKK-----KKERGHTVTEPIQPLEP 443
G E LP + P Q A + K+++K KKE + + + P
Sbjct: 393 GEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANP 452
Query: 444 ELPG-EGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPG-PPLNSESGEEAPTGRDKK 501
+P E QP A + PG P+ E G PP E+ E + DK
Sbjct: 453 AVPEVENQPPAGSNPG------------------PESEGSGVPPRPEEADETWDSKEDKI 494
Query: 502 RKQQQQQP 509
+ QP
Sbjct: 495 HNAENIQP 502
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.8 bits (133), Expect = 9e-08
Identities = 81/345 (23%), Positives = 110/345 (31%), Gaps = 33/345 (9%)
Query: 86 CP-QAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPG 144
CP QA + L P E + PQ + P Q L PL P+ A+PPPQ PP
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIA-TPPPQAPPALASPPLQGLPSPPLSPL-ATPPPQAPPX 624
Query: 145 LRPRFCAFGGNPPVTGPRSALA------PNLLTSGKKKKEMQVTEAPVTQEAVNGHGALE 198
L +PP + P S LA PN L + +P Q + +
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684
Query: 199 VDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKG 258
V + P Q P A+ P+ T P + P P
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 259 KETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPL 318
+ + P SP M P ++ P + PL
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-------MSPLAKPPPQAPPALATPPL 797
Query: 319 EEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEG-AKPQAQ 377
+ A+P PP PG P P SP T PQ P A P Q
Sbjct: 798 Q-ALPSPPASF------------PG---QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 378 AALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTK 422
+ P T + ++ T P+T V GP L L P P ++
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
Score = 38.5 bits (88), Expect = 0.015
Identities = 85/414 (20%), Positives = 124/414 (29%), Gaps = 49/414 (11%)
Query: 84 SSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPP 143
S PQA ++L+ P E L S L+ P SL+ PL+ +P+ PP +
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPS--------LQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 144 GLRPRFCAFGGNPPVTGPRSALA-PNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMA 202
P PP P A P+ LT+ + + P + A
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP-----------QAPPA 597
Query: 203 LGSPEMDVRKKKKKKNQQLKEP---EAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGK 259
L SP + Q L P A P P L PL P +
Sbjct: 598 LASPPL----------QGLPSPPLSPLATPPPQAPPXLALPPLQA--PPSPPASPPLSPL 645
Query: 260 ETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLE 319
T P+ + P P + + + P ++ P + PL
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL- 704
Query: 320 EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGA-KPQAQA 378
+ P PP P A P++ P SP P P P+
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-----PMSPSATPPPRVPP 759
Query: 379 ALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEP---QAAPTSTKKKKKKKERGHTVT 435
LAAP + + P + P+ P L QA P+ + + +
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 436 EPIQPL---EPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPL 486
P+ PL P+ P P S R P P + GP L
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Score = 35.0 bits (79), Expect = 0.16
Identities = 91/451 (20%), Positives = 138/451 (30%), Gaps = 64/451 (14%)
Query: 62 PLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGP 121
PLS S + +G + R P A P+T S P T L P
Sbjct: 298 PLSSSPLATPSPSGTKAR-----PVPPPDNAATPLPATLP------PSPPLATPLPLAPP 346
Query: 122 QQSLSGS--PLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRS--ALAPNLLTSGKKKK 177
S S L PA+PP Q PP + PP+ P S + P +
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMT--------TPPMQAPPSLQTIPPIQVPHSLTSP 398
Query: 178 EMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKK---KKKKNQQLKEPEAAGPVGTEP 234
+Q +P+ +L+ +LGSP + + Q + P T P
Sbjct: 399 SLQAPPSPLAL------SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 235 TVETLE-PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQ 293
L+ PL + + P P + PL+ + +
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSP---------LTIHPLQALSSLASHSPQAP 503
Query: 294 KGTEGMEPEEGVTVESQPQVKVEPLEEAIP----LPPTKKRKKEKGQMAMMEPGTEAMEP 349
+ M P E + + P ++ P P LP + + P E P
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET--P 561
Query: 350 VEPEMKPLESPGGTMAPQQPEGAK------PQAQAALAAPKKKTKKEKQQDATVEPETE- 402
P PL++P + PE PQA ALA+P + P +
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 403 ---VVGPELPDDLEPQAAP-----TSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEAR 454
+ P L P A+P + + H + P P P P +
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPP 680
Query: 455 ATPGSTKKRKKQSQESRMPETVPQEEMPGPP 485
A+P + SQ P + P PP
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
Score = 33.1 bits (74), Expect = 0.62
Identities = 50/259 (19%), Positives = 84/259 (32%), Gaps = 18/259 (6%)
Query: 241 PLGVLFPSTTKKRKKPKGKETFEPEDKTVKQ--EQINTEPLEDTVLSPTKKRKRQKGTEG 298
PLG + + +GK T P+ + + + P T +R R GTE
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 299 MEPEEGVTVESQPQVK------VEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEP 352
P + +P + E + P R++ + P + ++
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--- 244
Query: 353 EMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDL 412
PL SP + + P+A A + PK K + + P + P
Sbjct: 245 SATPLSSPARSGPSAR---GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 413 EPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRM 472
P A P+ + K + P+ P P P A P + Q+ S
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS-P 360
Query: 473 PETVPQEEMPG---PPLNS 488
P T P + P PP+ +
Sbjct: 361 PATPPSQAPPSMTTPPMQA 379
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 53.1 bits (126), Expect = 6e-07
Identities = 64/259 (24%), Positives = 100/259 (38%), Gaps = 30/259 (11%)
Query: 251 KKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEG-MEPEEGVTVES 309
KK K + T ++ T ++E+ +EP E T ++QK E +PE G ++
Sbjct: 113 KKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADA 172
Query: 310 QPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQP 369
+ K EP ++E GQ E TE E E ES + +
Sbjct: 173 NDRDKPEPKATVEEEDAKTASQEETGQRK--ECSTEPKEKATDEEAKAESQKAVVEDE-- 228
Query: 370 EGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKE 429
A A PK+ KE+ + E E ++ EP + ++ +K+
Sbjct: 229 ---------AKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEP 279
Query: 430 RGHTVTEPIQPLE-PELP-GEGQ--------PEARATPGSTKKRKKQSQESRMPETVPQE 479
G P P E PE P GEG P+ A+ G T +S S +P++ P+
Sbjct: 280 EGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVAS-GQTSPSASESSPSDVPQSPPES 338
Query: 480 EMPGPPLNSESGEEAPTGR 498
P + E E+AP R
Sbjct: 339 -----PSSGEKKEKAPERR 352
Score = 35.0 bits (79), Expect = 0.16
Identities = 42/200 (21%), Positives = 72/200 (36%), Gaps = 20/200 (10%)
Query: 329 KRKKEKGQMAMMEPGTEAMEPVE-PEMK----PLESPGGTMAPQQPEGAKPQAQAALAAP 383
+ K E+ + + E GT + PEM P E GT EG ++ AP
Sbjct: 16 REKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAP 75
Query: 384 KKKTKKEKQQ-------DATVEPETEVVGPE------LPDDLEPQAAPTSTKKKKKKKER 430
+ + Q + VE + E G E +D E + +++ +KE
Sbjct: 76 AEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEE 135
Query: 431 GHTVTEPIQPLEPELPGEGQP--EARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNS 488
+ + + E L E Q E A P S +K ++ P+ +EE
Sbjct: 136 TKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQE 195
Query: 489 ESGEEAPTGRDKKRKQQQQQ 508
E+G+ + K K ++
Sbjct: 196 ETGQRKECSTEPKEKATDEE 215
>gi|48375173 microtubule-associated protein 6 isoform 1 [Homo
sapiens]
Length = 813
Score = 52.0 bits (123), Expect = 1e-06
Identities = 62/280 (22%), Positives = 109/280 (38%), Gaps = 40/280 (14%)
Query: 252 KRKKPKGKETFEPEDKTVKQEQIN-TEPLEDTVLSPTKKRKRQKGTEGMEPEE------- 303
K+K +G T +P+DK +E N ++++ P + +G EP++
Sbjct: 409 KKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVP 468
Query: 304 GVTVESQPQVKVEPLEE---AIPLPPTKKRKKEKGQM---AMMEPGTEAMEPVEPEMKPL 357
G+ P V+ EPL++ +P PP K+ G M + + EP++ E +
Sbjct: 469 GLLKGQGPMVQ-EPLKKQGSVVPGPP-----KDLGPMIPLPVKDQDHTVPEPLKNESPVI 522
Query: 358 ESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQA- 416
+P P P K Q+ A K K Q + V + GP +P+ ++ QA
Sbjct: 523 SAPVKDQGPSVPVPPKNQSPMVPA-------KVKDQGSVVPESLKDQGPRIPEPVKNQAP 575
Query: 417 -APTSTKKK-----KKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQES 470
P K + K++G V+ P++ P +P + E P K E
Sbjct: 576 MVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVK------DEG 629
Query: 471 RMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQQQQPV 510
M +++ P P + + T K + +PV
Sbjct: 630 PMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPV 669
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 52.0 bits (123), Expect = 1e-06
Identities = 81/323 (25%), Positives = 133/323 (41%), Gaps = 40/323 (12%)
Query: 174 KKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLK---EPEAAGPV 230
KKK E +VT +E + E + A+ + + K + K +K + A
Sbjct: 316 KKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDE 375
Query: 231 GTEPTVETLEPLGVLFPSTTKKRKKPKG--------KETFEPEDKTVK------QEQINT 276
E + +T +P V P K+ KK K KE P DK VK +E+I
Sbjct: 376 KKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGA 435
Query: 277 EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK-VEPL---EEAIPLPPTKKRKK 332
++ V P KK ++ T E + + ++ +K EP+ EE +P +K +
Sbjct: 436 VSIKKAV--PGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE 493
Query: 333 EKGQMAMMEPGTEAMEPVEPEM--KPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKE 390
K M + G E ++P P++ K E P PQ + AKP + K+ K
Sbjct: 494 TKKDEKMSKAGKE-VKPKPPQLQGKKEEKP----EPQIKKEAKPAISEKVQIHKQDIVKP 548
Query: 391 KQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEP--IQPLEPELPGE 448
++ + +PE +V+ +E A P TKK + H EP I+ +P+ +
Sbjct: 549 EKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAE------HREREPPSIKTDKPKPTPK 602
Query: 449 GQPEARATPGSTKKRKKQSQESR 471
G E T KK + +ES+
Sbjct: 603 GTSE--VTESGKKKTEISEKESK 623
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/264 (20%), Positives = 107/264 (40%), Gaps = 37/264 (14%)
Query: 247 PSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVT 306
P T++ +P P +++++ + E V S TKK++++ + E E +
Sbjct: 293 PLPTEQASRPT------PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAID 346
Query: 307 VESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAP 366
VE + P K + ++G + + + + + K + P
Sbjct: 347 VEKKE--------------PGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEV--- 389
Query: 367 QQPEGAKPQAQAALAAPKKKTKKEKQ--QDATVEPETEVVGPELPDDLEPQAAP------ 418
+QP+G K + + P K KKE D V+ +TE E+ +A P
Sbjct: 390 EQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEK 449
Query: 419 -TSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVP 477
T T +++ +KE+ + ++ EP +G+ E P S K+++ ++++
Sbjct: 450 TTKTVEQEIRKEKSGKTSSILKDKEPI---KGKEE--KVPASLKEKEPETKKDEKMSKAG 504
Query: 478 QEEMPGPPLNSESGEEAPTGRDKK 501
+E P PP EE P + KK
Sbjct: 505 KEVKPKPPQLQGKKEEKPEPQIKK 528
Score = 43.9 bits (102), Expect = 3e-04
Identities = 53/258 (20%), Positives = 108/258 (41%), Gaps = 35/258 (13%)
Query: 265 EDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPL 324
+DKT KQE+ + ++ V K++ ++K E +PE+ T + + + K +P + +
Sbjct: 145 KDKTEKQEKPERK-IQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAK 203
Query: 325 PPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAK-PQAQAALAAP 383
K + EK + E + E+K GG + AK + Q + P
Sbjct: 204 EQKKAKTAEKSE-----------EKTKKEVK-----GGKQEKVKQTAAKVKEVQKTPSKP 247
Query: 384 KKKTKKEKQQDATVEPETE------VVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEP 437
K+K KEK + E + + ++ + DL+P +P ++ T P
Sbjct: 248 KEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT---P 304
Query: 438 IQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVP---QEEMPGPPLNSESG--- 491
P E GE + + TKK++K+ + + + +++ PG ++ G
Sbjct: 305 ASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVK 364
Query: 492 --EEAPTGRDKKRKQQQQ 507
+A +D+K++ ++
Sbjct: 365 IAAQAAAKKDEKKEDSKK 382
>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
Length = 1097
Score = 51.6 bits (122), Expect = 2e-06
Identities = 90/364 (24%), Positives = 143/364 (39%), Gaps = 55/364 (15%)
Query: 171 TSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPV 230
+S KKKK+++ +QE G +E + + KKK KN+ K +++ P
Sbjct: 539 SSTKKKKKVESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLKNKSSK--KSSKPP 596
Query: 231 GTEPTVE---TLEPLGVLFPSTTKKRKKPKGKETFEP-EDKTVKQEQINTEPLEDTVLSP 286
EP + ++P + T +K P E P E ++ QI P E +
Sbjct: 597 QKEPVEKGSAQMDPPQMGPAPTEAVQKGPVQVELPPPMEHAQMEGAQIRPAPDEPVQMEV 656
Query: 287 TKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEA 346
++ QK E + P VE V + + + LPP E Q + + G
Sbjct: 657 VQEGPAQK--ELLPP-----VEPAQMVGAQIVLAHMELPP----PMETAQTEVAQMGPAP 705
Query: 347 MEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGP 406
MEP + E+ +ES AP Q +P Q L+ P + +KE Q + P EVV
Sbjct: 706 MEPAQMEVAQVES-----APMQVVQKEP-VQMELSPPMEVVQKEPVQ-IELSPPMEVVQK 758
Query: 407 ELPDDLEPQAAPTSTKKKKKKKE----RGHTVTEPIQ---PLEPELPGEGQPEARATPGS 459
E P +E +K+ + E G EP Q P E P +P ++ P
Sbjct: 759 E-PVKIELSPPIEVVQKEPVQMELSPPMGVVQKEPAQREPPPPREPPLHMEPISKKPPLR 817
Query: 460 TKKRKKQSQESR---------------------MPETVPQEEM--PGPPLNSESGEEAPT 496
K++K + +S + E+V E++ P PPL E+ E +
Sbjct: 818 KDKKEKSNMQSERARKEQVLIEVGLVPVKDSWLLKESVSTEDLSPPSPPLPKENLREEAS 877
Query: 497 GRDK 500
G K
Sbjct: 878 GDQK 881
Score = 33.5 bits (75), Expect = 0.47
Identities = 49/250 (19%), Positives = 87/250 (34%), Gaps = 16/250 (6%)
Query: 175 KKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEP 234
K K+ + EA + N +E G DV KK +K+ + ++ + +
Sbjct: 426 KLKKTKKREADLPDNITNEKTEIEQTKIKG----DVAGKKNEKSVKAEKRDVSKEKKPSN 481
Query: 235 TVETLEPLGVLFPSTTKKRKKP----KGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKR 290
V ++ S T+ ++ E F K+ ++ ++++ L V
Sbjct: 482 NVSVIQVTTRTRKSVTEVKEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVNDEESST 541
Query: 291 KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPV 350
K++K E V E ++ + + K+K K + + EPV
Sbjct: 542 KKKKKVESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLKNKSSKKSSKPPQKEPV 601
Query: 351 EPEMKPLESPGGTMAPQQPEGA-KPQAQAALAAPKKKTKKEKQQ-----DATVEPETEVV 404
E ++ P M P E K Q L P + + E Q D V+ E
Sbjct: 602 EKGSAQMDPP--QMGPAPTEAVQKGPVQVELPPPMEHAQMEGAQIRPAPDEPVQMEVVQE 659
Query: 405 GPELPDDLEP 414
GP + L P
Sbjct: 660 GPAQKELLPP 669
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 51.6 bits (122), Expect = 2e-06
Identities = 109/476 (22%), Positives = 167/476 (35%), Gaps = 73/476 (15%)
Query: 84 SSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPP 143
+S P+ G AT PS++ L + P + P+Q + S + PA+P P P
Sbjct: 1449 TSAPKGGPAT---PSSKGDPTLPAVTPPSP--KEPPAPKQVATSSSPKKAPATPAPMGAP 1503
Query: 144 GLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMAL 203
L + P T P S P T+ K+ T AP +EA+ A+ V
Sbjct: 1504 TLPAVIPSSPKEVPAT-PSSRRDPIAPTATLLSKKTPATLAP--KEALIPP-AMTVPSPK 1559
Query: 204 GSPEMDVRKKKKK--KNQQLKEPEAAGPV---GTEPTVETLEPLGVLFPSTTKKRKKP-- 256
+P + K+ +++ P A P G E L P V PS + P
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV 1619
Query: 257 ------KGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGT-----EGMEPEEGV 305
KG T P+ T + L+D+ SP + T +G+ ++G
Sbjct: 1620 TPPSPEKGPATPAPKG-TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 306 TVESQPQVKVEPLEEAIPL--PPTKKRKKEKGQMAMMEP---------------GTEAME 348
T + +V V P E+ P+ PT+K + K A P T A
Sbjct: 1679 T--ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 349 PVEPEMKPLE----------SPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVE 398
P+ P K SP G +AP + + + P AA +K K + +
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF---EKVLPKPESASVSAA 1793
Query: 399 PETEVVGPELPDDLEPQAAPTSTKKKK-KKKERGHTVTEPIQPLEPELPGEGQPEARATP 457
P V P L P PT K++ G + P +PL P E P P
Sbjct: 1794 PSPPVSLP-----LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Query: 458 -------GSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQQ 506
S + + +P P + P N SG E+ + ++Q
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQ 1904
Score = 45.1 bits (105), Expect = 2e-04
Identities = 119/522 (22%), Positives = 161/522 (30%), Gaps = 70/522 (13%)
Query: 9 AARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRHVPLSGSQI 68
AA P A PP +P + A T P + L P AP P +
Sbjct: 1130 AATPPSPKGGLATPPPKGAP--TTPAATPPSPKGGLATPPPKGAPT------TPAATPPS 1181
Query: 69 VKGKLA--GKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLS 126
KG LA + ++ P + + L PS + G T A+ P L P S
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATPPSPKGGLATP--SPK 1238
Query: 127 GSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPV 186
G+P P P P+ P P A PP P S L L T K P
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGA--PTPPAATPPS-LKGGLATPPHKGAPNPAVVTPP 1295
Query: 187 TQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGV-L 245
+ + G G+P K P P T P V P G
Sbjct: 1296 SPK-----GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP--TPPAVTPPSPKGTPT 1348
Query: 246 FPSTTKKRK----KPKGKETFEPEDKTVKQE-----------------QINTEPLEDTV- 283
P+TT K P KE P T + +P V
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 284 -LSPTKKRKRQKGTEGME-PEEGVTVE---SQPQVKVEPLEEAIPLPPTKKRKKEKGQMA 338
LSP K EG P +G + +K P A P K +
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Query: 339 MMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVE 398
+ P + P ++ SP A P GA ++PK+ + +
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA 1528
Query: 399 PETEVVGPELPDDLEPQAA---PTSTKKKKKKKERGHTVTEPIQPLEPELPG-EGQPEAR 454
P ++ + P L P+ A P T KK P P E P EA
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKK--------TPAIPTPKEAPATPSSKEAS 1580
Query: 455 ATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPT 496
+ P T K + P+E + P + S S +EAPT
Sbjct: 1581 SPPAVTPSTYKGAPS-------PKELLIPPAVTSPSPKEAPT 1615
Score = 34.3 bits (77), Expect = 0.28
Identities = 124/564 (21%), Positives = 168/564 (29%), Gaps = 137/564 (24%)
Query: 48 PADFAPECFNGRHV-PLSGSQIVKG--KLAGKRHRYR-----VLSSCPQAGEATLLAPST 99
PA AP G + S ++G LA K H + L P A E +APS
Sbjct: 655 PAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714
Query: 100 EAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLR------------- 146
+ TCA P TL + +S+ P P+ PP PPG +
Sbjct: 715 QN----TCA--PLATLVLAPEIPKSV------PSPSLPPAGTPPGTKKVDGISHTSALAP 762
Query: 147 ----PRFCAFGGNPPVTGPRSALAPN---LLTSGKKKKEMQVTEAPVTQEAVNGHGALEV 199
P+ C P SA A + L + V+ +P T+ G+
Sbjct: 763 VASSPKEC-----PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP 817
Query: 200 DMALGS-------------PEMDVRKKKKKKNQQLKE-PEAAGPVG--TEPTVETLEPLG 243
D +G+ PE + + K + P P G T V L P G
Sbjct: 818 DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKG 877
Query: 244 VLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQ--KGTEGMEP 301
V P K+ P P++ L T SP K R KG
Sbjct: 878 VTLPP--KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS 935
Query: 302 EEGV-----------------------------TVESQPQVKVEPLEEAIPLPPTKKRKK 332
+G T S P + P PP
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 333 EKGQMAMME----PGTEAMEPVEPEMKPLESP-----------------GGTMAPQQPEG 371
KG A P A+ P P+ P +P G A P+G
Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 372 AKPQAQAALAAPK----KKTKKEKQQDATVEPETEVVGPELPD----DLEPQAAPTSTK- 422
A A L +PK + K P + GP P + P A P S K
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 423 KKKKKKERGHTVTEPIQPLEPE-----LPGEGQPEARATPGSTKKRKKQSQESRMPETVP 477
+G T P P+ P +G P TP +T K + P+ P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP---TTPAATPPSPKGGLATPPPKGAP 1172
Query: 478 QEEMPGPP-----LNSESGEEAPT 496
PP L + S + APT
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPT 1196
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 50.1 bits (118), Expect = 5e-06
Identities = 72/367 (19%), Positives = 128/367 (34%), Gaps = 46/367 (12%)
Query: 132 PIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKK-------EMQVTEA 184
P P++PPP+ G +P A PV + + +S ++KK T+
Sbjct: 293 PPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP 352
Query: 185 PVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGV 244
P ++A + E + KN K +P +P+G
Sbjct: 353 PPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGG 412
Query: 245 LFPSTTKKRKKPKG-KETFEPEDKTVKQEQINTEPLEDTVL--------SPTKKRKRQKG 295
T+K +E+ E++ K+ T+P +P R
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472
Query: 296 TEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTK--KRKKEKGQMAMMEPGTEAMEPVEPE 353
++ EE S+ VK +P + A P+K KK K + + ++ E E +
Sbjct: 473 SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Query: 354 MKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLE 413
+K SP +P+ K +AL A K K +++ + + VV
Sbjct: 533 LKGKGSP-------RPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVV--------- 576
Query: 414 PQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMP 473
+ + + KK+K+ E P + + TP + KRKK + + P
Sbjct: 577 --VSKSGSLKKRKQNEAAKEAETP----------QAKKIKLQTPNTFPKRKKGEKRASSP 624
Query: 474 ETVPQEE 480
+EE
Sbjct: 625 FRRVREE 631
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/232 (20%), Positives = 95/232 (40%), Gaps = 42/232 (18%)
Query: 288 KKRKRQKGTEGMEP--EEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTE 345
KK K++ + E EE V+ P K + + LPP K K + + E ++
Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKAS-ESSSSEESSD 134
Query: 346 AMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVG 405
+ + + +P++ +G KPQA+AA A PKK + D++ E E
Sbjct: 135 DDDEEDQKKQPVQ-----------KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP---- 179
Query: 406 PELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKK 465
P + +P+ P + K + K + I G+ + ++ S+
Sbjct: 180 ---PKNQKPKITPVTVKAQTKAPPKPARAAPKI--------ANGKAASSSSSSSSSSSSD 228
Query: 466 QSQESRM----PETVPQEEMPG---------PPLNSESGEEAPTGRDKKRKQ 504
S+E + +TVP++++ P S S E++ + ++++K+
Sbjct: 229 DSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280
Score = 43.5 bits (101), Expect = 5e-04
Identities = 74/363 (20%), Positives = 136/363 (37%), Gaps = 50/363 (13%)
Query: 177 KEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKN---QQLKEPEAAGP---V 230
K+ V +APV + + + E + +K K K + P A P +
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 231 GTEPT---------VETLEPLGVLFPSTTKKRKKPK-----GKETFEPEDKTVKQEQINT 276
GT+P VE+ E S++++ KKP K T +P E +
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSD 364
Query: 277 EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPT----KKRKK 332
D+ K T+ + VT +S P VK A P P K +
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKS-PAVK----PAAAPKQPVGGGQKLLTR 419
Query: 333 EKGQMAMMEPGTEAMEPVEPEMKPLESPGGTM-------APQQPEGAKPQAQAALAAPKK 385
+ + E + + E +M P T A Q P+G++ + + ++ +
Sbjct: 420 KADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE 479
Query: 386 KTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPEL 445
+ +++ + A + +V G P + P S KK K + + + + E +L
Sbjct: 480 EEEEKTSKSAVKKKPQKVAGGAAP------SKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 446 PGEG--QPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRK 503
G+G +P+A G++ + + ++ E +E+ + S+SG KKRK
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSL------KKRK 587
Query: 504 QQQ 506
Q +
Sbjct: 588 QNE 590
Score = 38.9 bits (89), Expect = 0.011
Identities = 66/377 (17%), Positives = 126/377 (33%), Gaps = 34/377 (9%)
Query: 155 NPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKK 214
N PV A + + ++E +V P + AV A V + G + +
Sbjct: 71 NGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVP---AKRVGLPPGKAA--AKASE 125
Query: 215 KKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQI 274
+++ + + +P + ++P + KK K ED+ K ++
Sbjct: 126 SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKP 185
Query: 275 NTEPLE---DTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRK 331
P+ T P R K G + S E+A P K
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 332 KEKGQMAMMEPGT-----------EAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAAL 380
K+ A ++ T + + E + KP+++ G + P A P ++
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 381 AAPKKKTKKEKQQDATVEPETEVVGPELPDDLEP------QAAPTSTKKKKKKKERGHTV 434
P KK +++Q + E ++ ++ +P A T KK E
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS 365
Query: 435 TEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPL-------N 487
++ + E P +P S K + P P++ + G +
Sbjct: 366 SDSDSSEDDEAP--SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADS 423
Query: 488 SESGEEAPTGRDKKRKQ 504
S S EE+ + ++K K+
Sbjct: 424 SSSEEESSSSEEEKTKK 440
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 50.1 bits (118), Expect = 5e-06
Identities = 80/346 (23%), Positives = 130/346 (37%), Gaps = 67/346 (19%)
Query: 141 IPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKK--KEMQVTEAPVTQEAVNGHGALE 198
+PP ++ F G P T A+ L ++GK+ K ++ + N
Sbjct: 1112 LPPEMKSFFTP--GKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGR 1169
Query: 199 VDMALGSPEMDV--------------RKKKKKKNQQLKEPEAAGPVGTE--PTVETLEPL 242
+ L S EMD +K K+ + L E P G + P E E L
Sbjct: 1170 IKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKL 1229
Query: 243 GVLFPSTTKKRKKPKGKETFE--------------PEDKTVKQEQINTEPLEDTVLSPTK 288
G+ + + +KPKG + PE+K +K++ + ED SP K
Sbjct: 1230 GMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILEN---EDEQNSPPK 1286
Query: 289 KRKRQK-------GTEGMEP-----EEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQ 336
K KR + GT EP ++G +S P E EE T+++ K K
Sbjct: 1287 KGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQH 1346
Query: 337 MAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDAT 396
A PE +ES T PQ+ G +P + + PKK + + + A
Sbjct: 1347 RVSRRAQQRA---ESPESSAIESTQST--PQKGRG-RPSKTPSPSQPKKNVRVGRSKQAA 1400
Query: 397 VE-----PETEVVGPELP-DDL------EPQAAPTSTKKKKKKKER 430
+ E +V P DD+ E + + + +++ K+ER
Sbjct: 1401 TKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRER 1446
Score = 34.3 bits (77), Expect = 0.28
Identities = 57/271 (21%), Positives = 93/271 (34%), Gaps = 36/271 (13%)
Query: 270 KQEQINTEPLEDTVLSP---TKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPP 326
K + E +D VL T+ K T+ P E + + + K + A+ P
Sbjct: 1079 KSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPL 1138
Query: 327 TKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKK 386
+ K+ + + + ME + A P P G + + + P KK
Sbjct: 1139 SSAGKQSQTKSSRMETVSNASSSSNPS-SPGRIKGRLDSSEMDHSENEDYTMSSPLPGKK 1197
Query: 387 TKK-----------EKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVT 435
+ K EK + P TE DDL K ++ ++RGHT +
Sbjct: 1198 SDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTAS 1257
Query: 436 EPIQPLEPELPG------EGQPEARATPGSTKKRKKQSQESRMPETVPQEE--------- 480
E + PE E + E + P KK K+ + P+EE
Sbjct: 1258 ESDEQQWPEEKRLKEDILENEDEQNSPP---KKGKRGRPPKPLGGGTPKEEPTMKTSKKG 1314
Query: 481 ---MPGPPLNSESGEEAPTGRDKKRKQQQQQ 508
GPP E EE + ++K + +Q
Sbjct: 1315 SKKKSGPPAPEEEEEEERQSGNTEQKSKSKQ 1345
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 50.1 bits (118), Expect = 5e-06
Identities = 56/230 (24%), Positives = 83/230 (36%), Gaps = 14/230 (6%)
Query: 263 EPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEP--EEGVTVESQPQVKVEPLEE 320
E E++ V +E+ E E+ V ++ G E E EE P V +EE
Sbjct: 1133 EDEEEVVAREEEEEEEEEEMV---AEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEE 1189
Query: 321 AIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAAL 380
+ + +E+ M P +E +P E PG + +P A+
Sbjct: 1190 EVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVE 1249
Query: 381 AAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQP 440
A P ++ + D VEPE ++ LP L+P P + T
Sbjct: 1250 ARPPLSPERAPEHDLEVEPEPPMM---LPLPLQPPLPPPRPPRPPSPPPEPETTDASHPS 1306
Query: 441 LEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSES 490
+ PE E P TPG K S+ ETVP PPL+ S
Sbjct: 1307 VPPEPLAEDHPP--HTPGLCGSLAK----SQSTETVPATPGGEPPLSGGS 1350
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/305 (20%), Positives = 109/305 (35%), Gaps = 43/305 (14%)
Query: 223 EPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDT 282
+P+ +P E +P ++ S++ + PK K+ + +D+ + E ++ P +
Sbjct: 152 DPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE--SSSPRRER 209
Query: 283 VLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKK---------- 332
S KK+ R + T +S+ + K + + + P K ++
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 333 -------EKGQMAMMEPGTEAMEPVEPEMK---------PLESPG--GTMAPQQPEGAKP 374
+ + A + T A+ P P PG T P PE A
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
Query: 375 QAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTV 434
Q + K K++ + PE GPE P APT ++
Sbjct: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP-------APTPLLAERHGGSPQPLA 382
Query: 435 TEPI--QPLEPELPGEGQPEARATPGSTKKRKKQ--SQESRMPETVPQEEMPGPPLNSES 490
T P+ +P+ P P E P +P + ++ Q S ES P P + + ES
Sbjct: 383 TTPLSQEPVNP--PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 491 GEEAP 495
+ AP
Sbjct: 441 PKPAP 445
Score = 40.8 bits (94), Expect = 0.003
Identities = 99/490 (20%), Positives = 163/490 (33%), Gaps = 87/490 (17%)
Query: 4 PQAGDAARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRHVPL 63
PQA +A P + A P + + + AL P + APA + R VPL
Sbjct: 2330 PQAPASANLVGPRSAHATAPVNIAGSRTAAALA-PASLTSARMAPALSGANLTSPR-VPL 2387
Query: 64 SGSQIVKGKLAGKRHRYRVLSSCPQAGEA-TLLAPSTEAGGGLTCASAPQGTLRILEGPQ 122
S + V G+ +S P A + PS + +T AP + R+ + P
Sbjct: 2388 SAYERVSGR-----------TSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPS 2436
Query: 123 QSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVT 182
QSL P Q P SP P C PV G +S L+SG
Sbjct: 2437 QSLL-PPAQDQPRSPVPSAFSD--QSRCLIAQTTPVAGSQS------LSSG--------A 2479
Query: 183 EAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPL 242
A T A + +G L V A G P DV EP A+ + L+P
Sbjct: 2480 VATTTSSAGDHNGMLSVP-APGVPHSDV-----------GEPPASTGAQQPSALAALQP- 2526
Query: 243 GVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPE 302
K+R+ + + S +
Sbjct: 2527 -------AKERRSSSSSSSSSSSSSS----------------SSSSSSSSSSSGSSSSDS 2563
Query: 303 EGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGG 362
EG ++ QP+V ++ + P P K +G+ P + S
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAP---KEAVREGRPPEPTPA--------KRKRRSSSSSS 2612
Query: 363 TMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPE-LPDDLEPQAAPTST 421
+ + + + ++ ++ + ++ P GP+ LP P+ P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE 2672
Query: 422 KKKKKKKERGHTVTE----PIQPLEPELPGEGQPEARATPGSTKK---RKKQSQESRMPE 474
++ + ++ ++ + P+E P QP R S+ + R+ Q +SR P
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSP-QPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Query: 475 TVPQEEMPGP 484
+ E P P
Sbjct: 2732 HKRRRETPSP 2741
Score = 38.1 bits (87), Expect = 0.019
Identities = 71/353 (20%), Positives = 121/353 (34%), Gaps = 66/353 (18%)
Query: 174 KKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQL------------ 221
K+K+ T AP ++ A H + D A S R +
Sbjct: 244 KRKRSRSTTPAPKSRRA---HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300
Query: 222 -KEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLE 280
+ E P T T P P T K+ +E +DK K+E+ T P
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSS---PETATKQPS----SPYEDKDKD-KKEKSATRP-- 350
Query: 281 DTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMM 340
SP+ +R + G EP P P ++ G +
Sbjct: 351 ----SPSPERS----STGPEP---------------------PAPTPLLAERHGGSPQPL 381
Query: 341 EPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPE 400
+ EPV P + SP +P + PQ+ ++ ++P + + A+ PE
Sbjct: 382 ATTPLSQEPVNPPSEA--SPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPE 439
Query: 401 TEVVGPELPDDLEPQAAPTSTKKK----KKKKERGHTVTEPI-QPLEPELPGEGQPEARA 455
+ P E ++PTS + K+ K HT + + + P G+ +R
Sbjct: 440 SPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR- 498
Query: 456 TP---GSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQ 505
TP G ++ R Q + SR + + P S S + R + +++
Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR 551
Score = 38.1 bits (87), Expect = 0.019
Identities = 78/402 (19%), Positives = 135/402 (33%), Gaps = 70/402 (17%)
Query: 108 ASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAP 167
+S+PQ ++ + P+Q P P+ + P R R + P + S L P
Sbjct: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR-RSRSVS-----PCSNVESRLLP 965
Query: 168 NLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAA 227
SG + +V +++ +G + K K Q P +
Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSG---------------SISPYPKVKAQTPPGPSLS 1010
Query: 228 GPVGTEPTVETLEPLGVLFPSTTK-----KRKKPKGKETFEPEDKTVK-QEQINTEPLED 281
G P ++ + L P + K P G+ F +K Q Q + + D
Sbjct: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
Query: 282 TVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMME 341
T S + R+ + ++ + + + P+ E P ++ + E M++
Sbjct: 1071 T--SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 342 PGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPET 401
G + PE +S + Q++ A K+K Q+DAT P
Sbjct: 1129 SG------MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP-- 1180
Query: 402 EVVGPELPDDLEP---QAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPG 458
P D P Q P S+ K T+ P P R+ G
Sbjct: 1181 ----PRQKDKFSPFPVQDRPESSLVFK------DTLRTP-------------PRERSGAG 1217
Query: 459 STKKRKKQ-------SQESRMPETVPQEEMPGPPLNSESGEE 493
S+ + K+Q SQ+ + E V + E P + S E
Sbjct: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSE 1259
Score = 34.3 bits (77), Expect = 0.28
Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 37/296 (12%)
Query: 109 SAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPN 168
S+P+ + ++SLSGS SP P+ PR G + P R+ +
Sbjct: 763 SSPRSKAKSRLSLRRSLSGS-------SPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815
Query: 169 LLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAG 228
+S K+ T + + + + H ++ G+P + N+Q P+
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS----GTPPRQGSITSPQANEQSVTPQRRS 871
Query: 229 PVGTEPTVETLEPLGVLFPS--TTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSP 286
+ P E L PS + P+ K + P + + +P ++SP
Sbjct: 872 CFESSPDPE----LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS--SPQPKVKAIISP 925
Query: 287 TKKRKRQKGTEGMEPEEGVTVESQPQVK--VEPLE--EAIPLPPTKKRKKEKGQMAMMEP 342
+++ G+ P VT + P+ V P E+ LP R G + P
Sbjct: 926 --RQRSHSGSSSPSPSR-VTSRTTPRRSRSVSPCSNVESRLLP----RYSHSGSSS---P 975
Query: 343 GTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVE 398
T+ V+PE P +S G+++P A+ +L+ K +EK +D+ V+
Sbjct: 976 DTK----VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQ 1027
Score = 30.0 bits (66), Expect = 5.2
Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 419 TSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQ 478
+S +++ +E EP +P L E TP KK+KK+ + R + P+
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYS--LVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 479 EEMPGPPLNSESGEEAPTGRDKKRKQQQQQP 509
E +S+ + KKRK + P
Sbjct: 207 RER---KKSSKKKKHRSESESKKRKHRSPTP 234
Score = 29.6 bits (65), Expect = 6.8
Identities = 69/371 (18%), Positives = 124/371 (33%), Gaps = 63/371 (16%)
Query: 172 SGKKKKEMQVTEAPVTQEAVNGH--GALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGP 229
SG EM + +E +NG LE D +L E R ++ P+A
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL--SPDAVEK 1393
Query: 230 VGTEPTVETLEPLGVLFPSTTKKRKK-----PKGKETFEPEDKTVKQEQINTEPLEDTVL 284
G P+ P T + + P+ K+ P + + ++ L D
Sbjct: 1394 AGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL-PRTPSRRSRSGSSPGLRDGSG 1452
Query: 285 SPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKK--------------- 329
+P++ + GM+ + + P +A+P P +
Sbjct: 1453 TPSR-HSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511
Query: 330 -RKKEKGQMAMMEPGTEAMEPV----------EPEMKPLESPGGTMAPQQPEGAKPQAQA 378
+++ G + ++ T A P+ E ++KP SP + + P ++A
Sbjct: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP----QERSESDSSPDSKA 1567
Query: 379 ALAAPKKKTKK-----EKQQDATVEPETEVVG--PELPDDLEPQAAPTSTKKKKKKKERG 431
P ++ + E + + P G PE+ D +P+AAP + +
Sbjct: 1568 KTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD--KPRAAP-------RAQSGS 1618
Query: 432 HTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESG 491
+ EP P LP R+ GS+ K + S E E P
Sbjct: 1619 DSSPEPKAPAPRALP------RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672
Query: 492 EEAPTGRDKKR 502
+P + K R
Sbjct: 1673 RSSPEPKTKSR 1683
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 49.3 bits (116), Expect = 8e-06
Identities = 66/286 (23%), Positives = 103/286 (36%), Gaps = 49/286 (17%)
Query: 206 PEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPK--GKETFE 263
P V + K + +K+ + G P + E GV T KPK G+ +
Sbjct: 1131 PIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC----TNCLDKPKFGGRNIKK 1186
Query: 264 PEDKTVKQEQINTEP----LEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLE 319
K K + + P L+ + KK K+ K +E + +E V++ +P
Sbjct: 1187 QCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTP 1246
Query: 320 EAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLE--SPGGTMAPQQPEGAKPQAQ 377
A P KK E P KP+E S G ++ PE Q
Sbjct: 1247 SAREDPAPKKSSSEP-----------------PPRKPVEEKSEEGNVSAPGPESK----Q 1285
Query: 378 AALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEP 437
A A +K +K+ Q + P+ GP P P+ P+ KKK
Sbjct: 1286 ATTPASRKSSKQVSQPALVIPPQPPTTGP--PRKEVPKTTPSEPKKK------------- 1330
Query: 438 IQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPG 483
QP PE E + + P + K++ +E P V ++E G
Sbjct: 1331 -QPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAG 1375
Score = 42.7 bits (99), Expect = 8e-04
Identities = 92/444 (20%), Positives = 153/444 (34%), Gaps = 78/444 (17%)
Query: 78 HRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRI---LEGPQQSLSGS------ 128
H R S + E + L P + L+ + +P T + P SL+ S
Sbjct: 753 HSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK 812
Query: 129 ----------PLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLT----SGK 174
P +P +S P + P P G+ G AP L+ + K
Sbjct: 813 NQRPRKQTSAPAEPFSSSSPTPLFPWFTP------GSQTERGRNKDKAPEELSKDRDADK 866
Query: 175 KKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEP 234
++ + E +E N + + RK+K+KK +++ A PVG
Sbjct: 867 SVEKDKSRERDREREKEN--------------KRESRKEKRKKGSEIQSSSALYPVG-RV 911
Query: 235 TVETLEPLGVLFPSTTKK---RKKPK-------------GKETFEPEDKTVKQEQINTEP 278
+ E + V S+ KK RKK G T +K+ + N E
Sbjct: 912 SKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEK 971
Query: 279 LEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKR-----KKE 333
+ L PT ++ T + TV+ L +A LP T KR KK
Sbjct: 972 -TNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKA 1030
Query: 334 KGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQ 393
K Q+ +E + +P+ + ES + + P +AA+A +K+
Sbjct: 1031 KAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKR------- 1083
Query: 394 DATVEPETEVVGPELPDDLEPQAAPTSTKKKKKK---KERGHTVTEPIQPLEPELPGEGQ 450
V P+ LP + + + K E + PI+P++P +
Sbjct: 1084 --AVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAP 1141
Query: 451 PEARATPGSTKKRKKQSQESRMPE 474
E G +R Q ++PE
Sbjct: 1142 QEPPVKKGRRSRRCGQCPGCQVPE 1165
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/388 (19%), Positives = 143/388 (36%), Gaps = 89/388 (22%)
Query: 193 GHGALE---VDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPST 249
G G LE +D+ +P ++ K+K L P ++ + ++ ++ P T
Sbjct: 965 GRGNLEKTNLDLGPTAPSLE-----KEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMT 1019
Query: 250 TKK----RKKPKGKETFEPEDKTVKQ------EQINTEPLEDTVLSPTKKRKRQKGTEGM 299
K+ KK K + + K++KQ + ++ E +V P K ++ +
Sbjct: 1020 DKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVAL 1079
Query: 300 EPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLES 359
+ V + P + P EE + + +K +A G+E EP+ P +KP++
Sbjct: 1080 GRKRAVFPDDMPTLSALPWEEREKIL-SSMGNDDKSSIA----GSEDAEPLAPPIKPIKP 1134
Query: 360 PGGTMAPQQPEGAKPQ-------------------------------------------- 375
APQ+P K +
Sbjct: 1135 VTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKC 1194
Query: 376 -------AQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKK 428
++A L K KK++++ T E + + + ++ PT + ++
Sbjct: 1195 QNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAP 1254
Query: 429 ERGHTVTEPIQPLEPELPGEGQ-----PEAR--ATPGSTKKRKKQSQESRMPETVPQEEM 481
++ + P +P+E E EG PE++ TP S K K+ SQ + + +P
Sbjct: 1255 KKSSSEPPPRKPVE-EKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALV---IP---- 1306
Query: 482 PGPPLNSESGEEAPTGRDKKRKQQQQQP 509
P PP +E P + K++Q P
Sbjct: 1307 PQPPTTGPPRKEVPKTTPSEPKKKQPPP 1334
Score = 36.2 bits (82), Expect = 0.073
Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
Query: 373 KPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGH 432
KP A KK+ E VE ++E P QA +++K K+
Sbjct: 1243 KPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ----- 1297
Query: 433 TVTEPIQPLEPELPGEGQPEA---RATPGSTKKRKKQSQESRMPETVPQEEMPGPPL 486
V++P + P+ P G P + TP KK++ ES ++ ++ P P +
Sbjct: 1298 -VSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSI 1353
Score = 33.5 bits (75), Expect = 0.47
Identities = 93/440 (21%), Positives = 156/440 (35%), Gaps = 87/440 (19%)
Query: 97 PSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPA-----SPP--------PQIPP 143
P T GGG G ++ L G+P Q +PA PP P PP
Sbjct: 13 PGTTGGGG--------------GGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPP 58
Query: 144 GLRPRFCAFG----GNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEV 199
+ A G G P SA + + +S + + + AL+V
Sbjct: 59 AVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQV 118
Query: 200 DMALGSPEMDVRKKKKKKNQQ-----LKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRK 254
A+G+ ++R+ + + E E G++ V P PS +
Sbjct: 119 SAAIGT---NLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSP--TRSPSVKTSPR 173
Query: 255 KPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK 314
KP+G+ P + + I ++P +V SP K E + G ++ +
Sbjct: 174 KPRGR----PRSGSDRNSAILSDP---SVFSPLNK---------SETKSGDKIKKKDSKS 217
Query: 315 VEPLEEAIPLPPTKKRKKEKGQ-MAMMEPGTEAMEPVEPEMKPLE-SPGGTMAPQQPEGA 372
+E P P K K G+ ++ + G + E +K ++ +P T QQ
Sbjct: 218 IEKKRGRPPTFPGVKIKITHGKDISELPKGNK-----EDSLKKIKRTPSATF--QQATKI 270
Query: 373 KPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGH 432
K L+ K K K K Q +G + + + P ST ER
Sbjct: 271 KKLRAGKLSPLKSKFKTGKLQ----------IGRKGVQIVRRRGRPPST-------ERIK 313
Query: 433 TVTEPIQPLEPELPGEGQPEARATPGSTKKRK---KQSQESRMP-ETVPQEEMPGPPLNS 488
T + + E E P + + + TP TK+ K +QS P +P + +
Sbjct: 314 TPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAK 373
Query: 489 ESGEEAPTGRDKKRKQQQQQ 508
+ + A G KK +++ Q
Sbjct: 374 QLLQRAKKGAQKKIEKEAAQ 393
Score = 31.2 bits (69), Expect = 2.3
Identities = 38/161 (23%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 117 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKK 176
+++ Q+ + P P + PP + GN GP S A T +K
Sbjct: 1237 VVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQAT---TPASRK 1293
Query: 177 KEMQVTEAPVT---QEAVNGHGALEVDMALGS---------PEMDVRKKKKKK------- 217
QV++ + Q G EV S PE + K+KK
Sbjct: 1294 SSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSI 1353
Query: 218 --NQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKP 256
Q+ KE E PV + TL L L + K+K P
Sbjct: 1354 PVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIP 1394
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 49.3 bits (116), Expect = 8e-06
Identities = 57/239 (23%), Positives = 87/239 (36%), Gaps = 24/239 (10%)
Query: 199 VDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTV---ETLEPLGVLFPSTTKKRKK 255
+D L ++ + K++ + ++ K P AA P V E +E GV
Sbjct: 662 LDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV----------S 711
Query: 256 PKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKV 315
+E E + TV N +++ SP + + G G +P + + P
Sbjct: 712 GNEEEMVEEAEATV-----NNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP 766
Query: 316 EPLEEAIPLP--PTKKRKKEKGQM-AMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGA 372
P E IP P PT + P A PV P+ + E ++ E
Sbjct: 767 TPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQ 826
Query: 373 KPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERG 431
KP A LA K ++ + + T E E GP D E A K +KKE G
Sbjct: 827 KPPAAEELAVDTGKAEEPVKSECTEEAEE---GPAKGKDAEAAEATAEGALKAEKKEGG 882
Score = 34.3 bits (77), Expect = 0.28
Identities = 46/236 (19%), Positives = 78/236 (33%), Gaps = 37/236 (15%)
Query: 270 KQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKK 329
K+++ E+ P + + + + EE + E++ V E+IP P T+
Sbjct: 682 KKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEA 741
Query: 330 RKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKK 389
K + GQ P T + P P P AP +P
Sbjct: 742 AK-DTGQNGPKPPATLGADGPPPG-PPTPPPEDIPAPTEPT------------------- 780
Query: 390 EKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEG 449
P +E G P P + K++KE P++ E + P
Sbjct: 781 ---------PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAA 831
Query: 450 QPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQ 505
+ A T + + K + E EE P ++E+ E G K K++
Sbjct: 832 EELAVDTGKAEEPVKSECTEE-------AEEGPAKGKDAEAAEATAEGALKAEKKE 880
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 48.9 bits (115), Expect = 1e-05
Identities = 64/282 (22%), Positives = 108/282 (38%), Gaps = 35/282 (12%)
Query: 210 VRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTV 269
+++K+K+K+Q+ KE E P P K + K + P TV
Sbjct: 1593 MQQKEKEKDQKPKEVEKQEDTENHPKTPESAP--------ENKDSELKTPPSVGPPSVTV 1644
Query: 270 KQEQINTEPLEDTVLSPTKKRKRQKGTEGMEP----EEGVTVESQPQVKVEPLEEAIPLP 325
+ LE T T + + +EP EE VE LE+ + LP
Sbjct: 1645 VTLESAPSALEKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPAPAPVEQLEQ-VDLP 1703
Query: 326 PTKKRKKEKGQM-AMMEPGTEAMEPVEPEMKPLESPGGTMAPQQ------PEGAKPQAQA 378
P KE M A +E G+ +P + KP +PG + + + P+ +P ++
Sbjct: 1704 PGADPDKEAAMMPAGVEEGSSGDQPPYLDAKP-PTPGASFSQAESNVDPEPDSTQPLSKP 1762
Query: 379 ALAAPKKKTKKEKQQDATVEPETEV---------VGPELPDDLEPQAAPTSTKKKKKKKE 429
A + + K ++ DAT + E + P +DLE + KK K +
Sbjct: 1763 AQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSK 1822
Query: 430 RGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESR 471
R T P+Q + +P R + +++ K+S R
Sbjct: 1823 RSKT---PVQAAAVSI--VEKPVTRKSERIDREKLKRSNSPR 1859
Score = 43.1 bits (100), Expect = 6e-04
Identities = 76/390 (19%), Positives = 140/390 (35%), Gaps = 48/390 (12%)
Query: 136 SPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHG 195
S PQ GL + + PV + ++ SG + Q+ + ++AV
Sbjct: 2124 SESPQKEDGLSSQL----KSDPVDPDKEPEKEDVSASGPSPEATQLAKQMELEQAVEHIA 2179
Query: 196 ALEVDMALGS-----PEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFP--- 247
L A + PE + + K Q E E A +G+ + EP P
Sbjct: 2180 KLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPY 2239
Query: 248 --STTKKRKKPKGKETFEPEDKTVKQEQ-----INTEPLEDTVLSPTKKRKRQKGTEGME 300
+ + P G + +P ++ ++ ++ + TE ++ P G +
Sbjct: 2240 PGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDPSAGPTDTK 2299
Query: 301 PEEGVTVE---SQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEM--- 354
G + E S P+ K E + K R+K + + PVE +
Sbjct: 2300 EARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPES 2359
Query: 355 ------KPLESPGGTMA-PQQPEGAKPQAQAALAAPKKKTK--------KEKQQDATVEP 399
P + G T+ P+ P+ K + P+ T + Q+ +VE
Sbjct: 2360 NQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEISVEE 2419
Query: 400 ETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTE--PI-QPLEPELPGEGQPEARAT 456
T +P DL P P ++ + + R H++ E P+ P +P +P P A
Sbjct: 2420 RTPTKA-SVPPDLPPPPQPAPVDEEPQARFRVHSIIESDPVTPPSDPSIPIPTLPSVTAA 2478
Query: 457 ----PGSTKKRKKQSQESRMPETVPQEEMP 482
P ++ QS +++ E + ++E P
Sbjct: 2479 KLSPPVASGGIPHQSPPTKVTEWITRQEEP 2508
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/369 (19%), Positives = 125/369 (33%), Gaps = 37/369 (10%)
Query: 159 TGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKN 218
T PR P +++E + E T + G + +K K +
Sbjct: 1946 TTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPK 2005
Query: 219 QQLKEPEAAGPVGTEPTVE--TLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINT 276
PEA VG + V+ ++EP + +++++ K T + +T E +
Sbjct: 2006 VDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEK 2065
Query: 277 EPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVK-----VEPLEEAIPLPPTKKR- 330
+P + K K G + V+ +K V P A +
Sbjct: 2066 KPAPE---------KNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGV 2116
Query: 331 ---KKEKGQMAMMEPGTEAM---EPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPK 384
EK + E G + +PV+P+ +P + P PE + Q L
Sbjct: 2117 VAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPS-PEATQLAKQMELEQAV 2175
Query: 385 KKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVT----EPIQ- 439
+ K + A+ + + P+D + A S + + G + EP
Sbjct: 2176 EHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQAS--ETELAAAIGSIINDISGEPENF 2233
Query: 440 PLEPELPGEGQPE------ARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEE 493
P P PGE Q + A+A S + + S + ET E PP+N+
Sbjct: 2234 PAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDPSA 2293
Query: 494 APTGRDKKR 502
PT + R
Sbjct: 2294 GPTDTKEAR 2302
Score = 38.9 bits (89), Expect = 0.011
Identities = 72/323 (22%), Positives = 119/323 (36%), Gaps = 64/323 (19%)
Query: 205 SPEMDVRKKKKKKNQQLKEPEA-----AGPVGTEPTVETLEPLGVLFPSTTKKRKKP-KG 258
S E + K +K EP+A A P P E LE + P K KKP K
Sbjct: 1766 SEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLE----VDPPVAAKDKKPNKS 1821
Query: 259 KETFEP----------EDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTE-GMEPEEGV-T 306
K + P + T K E+I+ E L+ S + + + QK E ME E+ T
Sbjct: 1822 KRSKTPVQAAAVSIVEKPVTRKSERIDREKLKR---SNSPRGEAQKLLELKMEAEKITRT 1878
Query: 307 VESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAP 366
+E E ++PL T++R M + E P +P+E P T
Sbjct: 1879 ASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDH-----ENRSPVKEPVEQPRVT--- 1930
Query: 367 QQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKK 426
+K+ ++E Q+ A V P P + P T+++
Sbjct: 1931 -----------------RKRLERELQEAAAV--------PTTPR----RGRPPKTRRRAD 1961
Query: 427 KKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMP-GPP 485
++E EP + L+P + G + KK E ++ T P+ GP
Sbjct: 1962 EEEENEA-KEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQ 2020
Query: 486 LNSESGEEAPTGRDKKRKQQQQQ 508
+ + P +++ +Q++
Sbjct: 2021 IGVKESSMEPKAAEEEAGSEQKR 2043
Score = 33.9 bits (76), Expect = 0.36
Identities = 86/427 (20%), Positives = 148/427 (34%), Gaps = 54/427 (12%)
Query: 87 PQAGEATLLAPSTEAGGG----------LTCASAPQGTLRILEGPQQSLSGSPLQPIPAS 136
P G + + T AGGG A+ P+ T + GPQ + S ++P A
Sbjct: 1977 PPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEV--GPQIGVKESSMEPKAAE 2034
Query: 137 PPPQIPPGLRPRFCAFGGNPPVTGPRSAL----APNLLTSGK------------KKKEMQ 180
+ NPP T P + AP + K K ++
Sbjct: 2035 EEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLK 2094
Query: 181 VTEAPVTQEAVNGH-GALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGT--EPTVE 237
+A V+ G E + SPE + + +K L + PV EP E
Sbjct: 2095 NVDAAVSPRGAAAQAGERESGVVAVSPE---KSESPQKEDGLSSQLKSDPVDPDKEPEKE 2151
Query: 238 TLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTE 297
+ G P T+ K+ + ++ E K + + + D + + + +
Sbjct: 2152 DVSASGPS-PEATQLAKQMELEQAVEHIAK-LAEASASAAYKADAPEGLAPEDRDKPAHQ 2209
Query: 298 GMEPEEGVTVESQ-PQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEP-GTEAMEPVEPEMK 355
E E + S + EP E P PP + Q + P G +A++P E M+
Sbjct: 2210 ASETELAAAIGSIINDISGEP--ENFPAPPPYPGES---QTDLQPPAGAQALQPSEEGME 2264
Query: 356 PLESPGGTMAPQQP-EGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEP 414
E+ G + + E ++P A + KE + +++ ET PE E
Sbjct: 2265 TDEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNSS---ETSHSVPEAKGSKEV 2321
Query: 415 QAAPT-------STKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQS 467
+ T + ++K+ V P++ PE A G+T + +
Sbjct: 2322 EVTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAP 2381
Query: 468 QESRMPE 474
QE + E
Sbjct: 2382 QEEKQSE 2388
Score = 33.5 bits (75), Expect = 0.47
Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 20/133 (15%)
Query: 291 KRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPV 350
+ + +G PE QP +P + A P PP+ + GQ +P + M V
Sbjct: 3336 RTKTAAQGPPPEGEPLQPPQPVQSTQPAQPAPPCPPS-----QLGQPG--QPPSSKMPQV 3388
Query: 351 EPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDAT-----VEPETEVVG 405
E K ++ G P+ P G A P+ T+ ++ Q T P + +
Sbjct: 3389 SQEAKGTQT--GVEQPRLPAG------PANRPPEPHTQVQRAQAETGPTSFPSPVSVSMK 3440
Query: 406 PELPDDLEPQAAP 418
P+LP L Q AP
Sbjct: 3441 PDLPVSLPTQTAP 3453
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 48.9 bits (115), Expect = 1e-05
Identities = 102/446 (22%), Positives = 159/446 (35%), Gaps = 98/446 (21%)
Query: 138 PPQIPPG-----LRPRFCAFGGNPP----VTGPRSALAPNLLTSGKKKKEMQVTEAPVTQ 188
PPQI P +R R GG ++G R+A P +G + E P
Sbjct: 4 PPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA 63
Query: 189 EAVN----GHGALEVDM-ALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLG 243
V GA+ D L PE + + P G+EP + L G
Sbjct: 64 VIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPG 123
Query: 244 VLFPST--TKKRKKPKGKETFEPE--------------------DKTVKQEQINTEPLE- 280
+ + + P +ET EP K V + + ++ PL+
Sbjct: 124 DTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA 183
Query: 281 -DTVLSPTKKRKRQKG---TEGMEPEEGVTVESQPQVKVEPL---EEAIPLPPTKKRKKE 333
+ S T + G +E +EPE VES P++ P E +P+ PT + +E
Sbjct: 184 PTPLASHTVEIHEPNGMVPSEDLEPE----VESSPELAPPPACPSESPVPIAPTAQ-PEE 238
Query: 334 KGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQ 393
A P + EPE + E +MAP A P + +P ++ + E+++
Sbjct: 239 LLNGAPSPPAVDLSPVSEPEEQAKEVTA-SMAPPTIPSATPATAPSATSPAQEEEMEEEE 297
Query: 394 D-------ATVEPETEVVGPE-LPDDLEP---------------QAAPTSTKKKKK---- 426
+ E E+E G E LP + P Q A + K+++K
Sbjct: 298 EEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKEL 357
Query: 427 -KKERGHTVTEPIQPLEPELPG-EGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPG- 483
KKE + + + P +P E QP A + PG P+ E G
Sbjct: 358 NKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPG------------------PESEGSGV 399
Query: 484 PPLNSESGEEAPTGRDKKRKQQQQQP 509
PP E+ E + DK + QP
Sbjct: 400 PPRPEEADETWDSKEDKIHNAENIQP 425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,086,487
Number of Sequences: 37866
Number of extensions: 1726104
Number of successful extensions: 12039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 1128
Number of HSP's that attempted gapping in prelim test: 8338
Number of HSP's gapped (non-prelim): 3810
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.