BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|68160937 tripartite motif-containing 25 [Homo sapiens] (630 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|68160937 tripartite motif-containing 25 [Homo sapiens] 1301 0.0 gi|54792146 tripartite motif-containing 47 [Homo sapiens] 187 2e-47 gi|48255913 tripartite motif-containing 16 [Homo sapiens] 155 1e-37 gi|148833499 midline 1 [Homo sapiens] 152 9e-37 gi|4557753 midline 1 [Homo sapiens] 152 9e-37 gi|15451852 midline 1 [Homo sapiens] 152 9e-37 gi|223890259 midline 2 isoform 2 [Homo sapiens] 144 3e-34 gi|223890257 midline 2 isoform 1 [Homo sapiens] 140 3e-33 gi|38679905 tripartite motif-containing 65 [Homo sapiens] 132 1e-30 gi|148596968 tripartite motif-containing 8 [Homo sapiens] 126 5e-29 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 125 9e-29 gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] 115 1e-25 gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ... 103 5e-22 gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ... 103 5e-22 gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ... 103 5e-22 gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] 91 4e-18 gi|22749269 ring finger protein 129 [Homo sapiens] 86 1e-16 gi|89886468 fibronectin type III and SPRY domain containing 1-li... 82 1e-15 gi|223718222 fibronectin type III and SPRY domain containing 1-l... 82 1e-15 gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 81 3e-15 gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 81 3e-15 gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ... 80 4e-15 gi|27734883 tripartite motif family-like 2 [Homo sapiens] 80 6e-15 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 79 1e-14 gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens] 79 2e-14 gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens] 79 2e-14 gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens] 79 2e-14 gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens] 79 2e-14 gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo... 78 3e-14 gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ... 78 3e-14 >gi|68160937 tripartite motif-containing 25 [Homo sapiens] Length = 630 Score = 1301 bits (3367), Expect = 0.0 Identities = 630/630 (100%), Positives = 630/630 (100%) Query: 1 MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR 60 MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR Sbjct: 1 MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR 60 Query: 61 PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL 120 PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL Sbjct: 61 PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL 120 Query: 121 VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180 VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL Sbjct: 121 VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180 Query: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ Sbjct: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240 Query: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT 300 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT Sbjct: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT 300 Query: 301 KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP 360 KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP Sbjct: 301 KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP 360 Query: 361 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL 420 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL Sbjct: 361 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL 420 Query: 421 EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS 480 EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS Sbjct: 421 EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS 480 Query: 481 VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES 540 VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES Sbjct: 481 VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES 540 Query: 541 RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600 RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM Sbjct: 541 RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600 Query: 601 YKFRVDFTEALYPAFWVFSAGATLSICSPK 630 YKFRVDFTEALYPAFWVFSAGATLSICSPK Sbjct: 601 YKFRVDFTEALYPAFWVFSAGATLSICSPK 630 >gi|54792146 tripartite motif-containing 47 [Homo sapiens] Length = 638 Score = 187 bits (476), Expect = 2e-47 Identities = 186/675 (27%), Positives = 275/675 (40%), Gaps = 118/675 (17%) Query: 12 SCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYL--------CPQCRAVYQARPQL 63 SC ICLEP +EPVT PCGHNFC +CL W +G+ CP C+ + QL Sbjct: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67 Query: 64 HKNTVLCNVVEQFLQAD-----------LAREPPADVWTP----PARASAPSP----NAQ 104 KN L ++ Q Q LA EP A P P+ AP P Sbjct: 68 RKNHTLSELL-QLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEP 126 Query: 105 VACDHCLKEAAVK---TCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHN 161 V CD C + AA+ +CL C+ASFC HL PH SPA + H L PP+R L C +H Sbjct: 127 VRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHL 186 Query: 162 RLREFFCPEHSECICHICLV-EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRAL 220 R E +C C+C C EH+ L Q A EA L+ + +++ + Sbjct: 187 RPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGI 246 Query: 221 DDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQI 280 R ++ A + E++ + + + A L +T I+E E + + + Sbjct: 247 AQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRR 306 Query: 281 LLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQS 340 +++S + ++ + Q + + D FL Q Sbjct: 307 QEEQRSRLSRARQNLSQ-VPEADSVSFL------------------------------QE 335 Query: 341 TIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALP 400 + L+ L+ G P G P E + ++ R V+ + A Sbjct: 336 LLALRLALEDGCG------PGPGPPRELSFTKSSQAVRAVRDML-----------AVACV 378 Query: 401 SKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVI 460 ++ P D Q L++ A A ST+L LE+ R L++ V Sbjct: 379 NQWEQLRGPGGNEDGPQK-LDSEADAEPQDLESTNL----LES--EAPRDYFLKFAYIVD 431 Query: 461 LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQK 520 LD +TA + L V V P NY P RFT+C QVLG +G +YWEVE+ + Sbjct: 432 LDSDTADKFLQLFGTKGVKRVL-CPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIE 490 Query: 521 NNFCGVGICYGSMNRQGP--ESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVG 578 + +G+ + Q P RLGRN+ S C++W S W + +E LP + VG Sbjct: 491 G-WVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVG 549 Query: 579 VLLNCDHGFVIFFAVAD-KVHLM--------------------YKFRVD------FTEAL 611 V L + F+AV D K+ L+ ++ R+D FT L Sbjct: 550 VCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRL 609 Query: 612 YPAFWVFSAGATLSI 626 PAF++ S A L I Sbjct: 610 KPAFFLESVDAHLQI 624 >gi|48255913 tripartite motif-containing 16 [Homo sapiens] Length = 564 Score = 155 bits (392), Expect = 1e-37 Identities = 131/522 (25%), Positives = 225/522 (43%), Gaps = 67/522 (12%) Query: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159 +V CD CL + AVK+CL CM ++C+EHLQPH + Q H L PV+D R C Sbjct: 74 EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133 Query: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRA 219 H+ FC +CIC C EH + SL A D EA L+ + ++ A Sbjct: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENA 193 Query: 220 LDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQ 279 + ++ Q+ V ++ + + ++ E+ A + ++ ++E+E+ S+ + I Sbjct: 194 ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKA 253 Query: 280 ILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQ 339 L + +E++ K+E+E+ + +FLE+ K + +T+ + P V Sbjct: 254 HLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK--NTEDITFPSVY----------- 300 Query: 340 STIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPAL 399 + LK++L + E T V + E KK Sbjct: 301 --VGLKDKLSGIRKVITEST--------------------VHLIQLLENYKKK------- 331 Query: 400 PSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKV 459 L F E+ Q K +S P ++ R + L+Y + Sbjct: 332 ---LQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST-------------REQFLQYAYDI 375 Query: 460 ILDYNTAHNKVALSE-CYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518 D +TAH + L E V + Y P RF + QVL +Y+EVE+ Sbjct: 376 TFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI 435 Query: 519 QKNNFCGVGICYGSMNRQGPE--SRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATR 576 VG+ ++R+G E S + N+ SW ++W + +AW++++E L + R Sbjct: 436 FGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRR 494 Query: 577 VGVLLNCDHGFVIFFAVA-DKVHLMYKFRVDFTEALYPAFWV 617 +GV ++ G + F+ V D + L++KF F+E +Y AFW+ Sbjct: 495 LGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536 >gi|148833499 midline 1 [Homo sapiens] Length = 667 Score = 152 bits (384), Expect = 9e-37 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57 L EL+C ICLE F++P+ PC H+ C +C + +V+ + + CP CR V Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63 Query: 58 QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111 + L +N L N++++F +A ++ P++ A A+ + +V C C Sbjct: 64 TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123 Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164 ++ AVKTC+ C S+C E L+ H + F H L P+ D R C +H + Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183 Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222 +C + IC +C + H+ A+LS+ L+ L LT + + L Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243 Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278 + Q V + A+R+ +L +E + ++ KIKE + +++ + Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303 Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333 Q + + S L + E SL + D FL+ A + ++ V IPE+ LN Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358 Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391 +D E K +C+ L P P + + + T V S +E Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410 Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447 V + + F +V L + +H L++ F+ K Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466 Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499 S P L+ + LD +AH K+ +S E P+RFT Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526 Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557 V G G HYWEV + + + +G+ Y S + +G+NSASW + N Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583 Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616 HN+ E + P+ RVG+LL+ D+G + F+ + +HL Y F V F + + P F Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642 Query: 617 VFSAGATL 624 V++ T+ Sbjct: 643 VWNKCLTI 650 >gi|4557753 midline 1 [Homo sapiens] Length = 667 Score = 152 bits (384), Expect = 9e-37 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57 L EL+C ICLE F++P+ PC H+ C +C + +V+ + + CP CR V Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63 Query: 58 QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111 + L +N L N++++F +A ++ P++ A A+ + +V C C Sbjct: 64 TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123 Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164 ++ AVKTC+ C S+C E L+ H + F H L P+ D R C +H + Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183 Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222 +C + IC +C + H+ A+LS+ L+ L LT + + L Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243 Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278 + Q V + A+R+ +L +E + ++ KIKE + +++ + Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303 Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333 Q + + S L + E SL + D FL+ A + ++ V IPE+ LN Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358 Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391 +D E K +C+ L P P + + + T V S +E Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410 Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447 V + + F +V L + +H L++ F+ K Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466 Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499 S P L+ + LD +AH K+ +S E P+RFT Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526 Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557 V G G HYWEV + + + +G+ Y S + +G+NSASW + N Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583 Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616 HN+ E + P+ RVG+LL+ D+G + F+ + +HL Y F V F + + P F Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642 Query: 617 VFSAGATL 624 V++ T+ Sbjct: 643 VWNKCLTI 650 >gi|15451852 midline 1 [Homo sapiens] Length = 667 Score = 152 bits (384), Expect = 9e-37 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57 L EL+C ICLE F++P+ PC H+ C +C + +V+ + + CP CR V Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63 Query: 58 QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111 + L +N L N++++F +A ++ P++ A A+ + +V C C Sbjct: 64 TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123 Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164 ++ AVKTC+ C S+C E L+ H + F H L P+ D R C +H + Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183 Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222 +C + IC +C + H+ A+LS+ L+ L LT + + L Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243 Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278 + Q V + A+R+ +L +E + ++ KIKE + +++ + Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303 Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333 Q + + S L + E SL + D FL+ A + ++ V IPE+ LN Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358 Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391 +D E K +C+ L P P + + + T V S +E Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410 Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447 V + + F +V L + +H L++ F+ K Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466 Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499 S P L+ + LD +AH K+ +S E P+RFT Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526 Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557 V G G HYWEV + + + +G+ Y S + +G+NSASW + N Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583 Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616 HN+ E + P+ RVG+LL+ D+G + F+ + +HL Y F V F + + P F Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642 Query: 617 VFSAGATL 624 V++ T+ Sbjct: 643 VWNKCLTI 650 >gi|223890259 midline 2 isoform 2 [Homo sapiens] Length = 705 Score = 144 bits (362), Expect = 3e-34 Identities = 155/659 (23%), Positives = 255/659 (38%), Gaps = 63/659 (9%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56 L EL+C ICLE F++P+ PC H+ C SC + S + CP CR V Sbjct: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83 Query: 57 ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111 ++ L +N L N++++F +A ++ P R + + ++AC C Sbjct: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143 Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164 ++ AVKTC+ C S+C L+ H + F H L PV D R C H N Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203 Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222 +C + IC +C + H+ ASL+ L+ TL LT + + + + Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263 Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282 + Q V + +L +E E+ ++ + KIKE + K Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323 Query: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337 + L + E L + D+ FL+ A + ++ V IP++ N Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379 Query: 338 HQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVP 397 +D E K G P+ E ++H T V +S +E + Sbjct: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH-DTITVHWISDDEFS------IS 432 Query: 398 ALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-------- 447 + + F + L + +H L++ F+ K Sbjct: 433 SYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSR 492 Query: 448 -SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRF--TYCSQVLG 503 S P L+ + LD H K+ +S E P+RF T C G Sbjct: 493 NSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAG 552 Query: 504 LHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHN 563 G HYWEV + + + +GI Y S + +G+N++SW N+ HN Sbjct: 553 NIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPK---NEWIGKNASSWVFSRCNSNFVVRHN 609 Query: 564 NVEKTL---PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619 N E + P K R+GVLL+ D+ + F+ A+ +HL + F V F + P F +++ Sbjct: 610 NKEMLVDVPPHLK--RLGVLLDYDNNMLSFYDPANSLHL-HTFDVTFILPVCPTFTIWN 665 >gi|223890257 midline 2 isoform 1 [Homo sapiens] Length = 735 Score = 140 bits (354), Expect = 3e-33 Identities = 161/689 (23%), Positives = 261/689 (37%), Gaps = 93/689 (13%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56 L EL+C ICLE F++P+ PC H+ C SC + S + CP CR V Sbjct: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83 Query: 57 ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111 ++ L +N L N++++F +A ++ P R + + ++AC C Sbjct: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143 Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164 ++ AVKTC+ C S+C L+ H + F H L PV D R C H N Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203 Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222 +C + IC +C + H+ ASL+ L+ TL LT + + + + Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263 Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282 + Q V + +L +E E+ ++ + KIKE + K Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323 Query: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337 + L + E L + D+ FL+ A + ++ V IP++ N Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379 Query: 338 HQSTIDLKNELK--QCIGRLQEPTPSSGD----PGEHDPASTHKSTRPVKKVSKEE---- 387 +D E K + + L P P S HD + H + +S E Sbjct: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYT 439 Query: 388 ----------------------KKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425 +K K+ L GAP L + + + Sbjct: 440 IFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLA------GAPRGLYNSVDSWM-IVPN 492 Query: 426 ATSSHPNSTSLKAKVLETFLAK---------SRPELLEYYIKVI-LDYNTAHNKVALSEC 475 +H L++ F+ K S P L+ + LD H K+ +S Sbjct: 493 IKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISND 552 Query: 476 YTVASVAEMPQNYRPHPQRF--TYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSM 533 E P+RF T C G G HYWEV + + + +GI Y S Sbjct: 553 GLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSA 612 Query: 534 NRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTL---PSTKATRVGVLLNCDHGFVIF 590 + +G+N++SW N+ HNN E + P K R+GVLL+ D+ + F Sbjct: 613 PK---NEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLK--RLGVLLDYDNNMLSF 667 Query: 591 FAVADKVHLMYKFRVDFTEALYPAFWVFS 619 + A+ +HL + F V F + P F +++ Sbjct: 668 YDPANSLHL-HTFDVTFILPVCPTFTIWN 695 >gi|38679905 tripartite motif-containing 65 [Homo sapiens] Length = 517 Score = 132 bits (331), Expect = 1e-30 Identities = 143/627 (22%), Positives = 231/627 (36%), Gaps = 138/627 (22%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKN 66 L E+L+C+ICL +++PVT PCGHNFCG+C+ + W G CP+CR + +L +N Sbjct: 6 LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA--CPECREPFPDGAELRRN 63 Query: 67 TVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASF 126 L V+E ++A AR+P P P P A Sbjct: 64 VALSGVLE-VVRAGPARDPG------PDPGPGPDPAA----------------------- 93 Query: 127 CQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV-EHKT 185 +C +H R E FC C+C +C V E + Sbjct: 94 -----------------------------RCPRHGRPLELFCRTEGRCVCSVCTVRECRL 124 Query: 186 CSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEY 245 A L EA LR L V Q A L ++R + ++ +A + ++ Sbjct: 125 HERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKF 184 Query: 246 TEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEF 305 + + L+ TT+ R I+ + Q L + + E Q L+ +E Sbjct: 185 SSLLQALEIQHTTALRSIEVAKT----------QALAQARDEEQRLRVHLEA-------- 226 Query: 306 EFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDP 365 ++R +L++ + + T +++L Q G L TP D Sbjct: 227 -VARHGCRIR----------------ELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDE 269 Query: 366 GEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425 + +R + +E P PA P L AP L + Sbjct: 270 DQQLGDLKQLLSRLCGLLLEEGSH----PGAPAKPVDLAPVEAPGPLAPVPST------- 318 Query: 426 ATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMP 485 + R +L + Y + D +A+ LS V Sbjct: 319 -------------------VCPLRRKLWQNYRNLTFDPVSANRHFYLSR--QDQQVKHCR 357 Query: 486 QNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNR--QGPES-RL 542 Q+ P QV ++ G HYWEV ++ +G+ Y + R GP + + Sbjct: 358 QSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVT-LGVSYPQLPRCRLGPHTDNI 416 Query: 543 GRNSASW--CVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600 GR SW CV+ + AWHN + LP +G+ L+ G + F+++ + + Sbjct: 417 GRGPCSWGLCVQ--EDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPL 474 Query: 601 YKFRVDFTEALYPAFWVFSAGATLSIC 627 Y F F + L P FW+ G TL++C Sbjct: 475 YTFHALFNQPLTPVFWLLE-GRTLTLC 500 >gi|148596968 tripartite motif-containing 8 [Homo sapiens] Length = 551 Score = 126 bits (317), Expect = 5e-29 Identities = 85/314 (27%), Positives = 129/314 (41%), Gaps = 25/314 (7%) Query: 9 EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTV 68 EEL C ICL F EPV PC HNFC C+ E WA CP+C Y +P L KN Sbjct: 11 EELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLK 70 Query: 69 LCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQ 128 L N+VE+F A +PPA + R P P A K CL C A CQ Sbjct: 71 LTNIVEKF-NALHVEKPPAALHCVFCRRGPPLP-------------AQKVCLRCEAPCCQ 116 Query: 129 EHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSP 188 H+Q H P+ L D+ C QHN R + C +C C S Sbjct: 117 SHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCY----YSG 172 Query: 189 ASLSQASADLEA---TLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQE- 244 A + D+E +R L ++ + ++D + + + KV QL++E Sbjct: 173 AHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEV 232 Query: 245 ---YTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTK 301 Y ++ LLD + + + + + S+ L ++ E + L ++ K Sbjct: 233 RLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDK 292 Query: 302 RDEFEFLEKASKLR 315 ++ F++ ++ Sbjct: 293 TEDVSFMKNTKSVK 306 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 125 bits (315), Expect = 9e-29 Identities = 142/619 (22%), Positives = 230/619 (37%), Gaps = 144/619 (23%) Query: 2 AELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARP 61 A L L E SCS+CLE KEPV CGHNFC +C+ W Sbjct: 18 AALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE------------------- 58 Query: 62 QLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLV 121 DL R+ P V +R + PN Q+ +V Sbjct: 59 ------------------DLERDFPCPVCRKTSRYRSLRPNRQLGS------------MV 88 Query: 122 CMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV 181 +A Q ++ +RD C QH+ FC E E +C IC + Sbjct: 89 EIAKQLQA---------------VKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAI 131 Query: 182 E--HKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239 H+ + L A+ + + L+ L + ++ +R + +++ + + Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191 Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299 Q+ +E+ E+ LD + +++EEE+ + +Q L+E Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDI-----------------LQRLRENAAHLG 234 Query: 300 TKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPT 359 KR + L E+ K ++ + D+K+ L++ I R + Sbjct: 235 DKRRDLAHL-----------------AAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGS 277 Query: 360 PSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAG 419 S+ P +H VK++++ E K+ T ++L+ Sbjct: 278 LSTICPRDHKAL-----LGLVKEINRCE--------------KVKTMEVTSVSIELE--- 315 Query: 420 LEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVA 479 K S+ P K+L+ +A V LD TAH + LSE Sbjct: 316 -----KNFSNFPRQYFALRKILKQLIA-----------DVTLDPETAHPNLVLSEDRKSV 359 Query: 480 SVAEMPQNYRPH-PQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGP 538 E P P+RFT+ VL + G HYWEVE+ VG+C S++R+G Sbjct: 360 KFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGE 419 Query: 539 ESRLGRNSASWCVE-WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKV 597 + L + W V W K +A K RVG+ L+ + G + F+ V D+ Sbjct: 420 LTPL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRS 478 Query: 598 HLMYKFRVDFTEALYPAFW 616 H+ Y F FTE L+P F+ Sbjct: 479 HI-YTFTDTFTEKLWPLFY 496 >gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] Length = 588 Score = 115 bits (288), Expect = 1e-25 Identities = 76/257 (29%), Positives = 128/257 (49%), Gaps = 14/257 (5%) Query: 100 SPNAQVACDHCL--KEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKC 157 S + +V CD C+ K+ AVK+CLVC ASFC+ HL+PH + AF+DH L P+RD RKC Sbjct: 166 SGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKC 225 Query: 158 SQHNRLREFFCPEHSECICHICLV-EHKTCSPASLSQASADLEATL---RHKLTVMYSQI 213 H + E FC CIC++C+ EHK S ++ +A A+ E L + +L + +I Sbjct: 226 PVHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEI 285 Query: 214 NGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSK 273 + ++R + T N K L+Q + ++ L+ + +++ E+ + Sbjct: 286 EDEAEKWQKEKDRIKS--FTTNEKA-ILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQ 342 Query: 274 FDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKL 333 I L ++ + K+ EQ + D FL++ L + P P + H L Sbjct: 343 VKVIMDALDERAKVLHEDKQTREQLHSISDSVLFLQEFGALMSNYSLP---PPLPTYHVL 399 Query: 334 I--KGIHQSTIDLKNEL 348 + +G+ QS + K++L Sbjct: 400 LEGEGLGQSLGNFKDDL 416 >gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 103 bits (257), Expect = 5e-22 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%) Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214 +C +H +R+ E FC C+C +C V Sbjct: 23 RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49 Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274 L R + + A V++L QE + A+ + +I++ +++ + Sbjct: 50 -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104 Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334 ++ L K +E++ L +E E++L K+ F++K ++L T VY + + + Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153 Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393 +D+ N+L + + QEP DP + A T +++S E P Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200 Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449 P+ P K G E + Q L+ K + S P+ST +L+T + R Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259 Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503 LL+Y LD +T H ++ LS C + S+ +P RF QVL Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313 Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560 C+ G HYWEV++Q+ VG Y S+ R+G + RLG N SWC++ ++ + A Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373 Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619 +H+ L P R+GV L+ + G + F+ V + ++ FR F E LYPA ++ Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433 Query: 620 AGATL 624 ++ Sbjct: 434 GAISI 438 >gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 103 bits (257), Expect = 5e-22 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%) Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214 +C +H +R+ E FC C+C +C V Sbjct: 23 RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49 Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274 L R + + A V++L QE + A+ + +I++ +++ + Sbjct: 50 -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104 Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334 ++ L K +E++ L +E E++L K+ F++K ++L T VY + + + Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153 Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393 +D+ N+L + + QEP DP + A T +++S E P Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200 Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449 P+ P K G E + Q L+ K + S P+ST +L+T + R Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259 Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503 LL+Y LD +T H ++ LS C + S+ +P RF QVL Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313 Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560 C+ G HYWEV++Q+ VG Y S+ R+G + RLG N SWC++ ++ + A Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373 Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619 +H+ L P R+GV L+ + G + F+ V + ++ FR F E LYPA ++ Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433 Query: 620 AGATL 624 ++ Sbjct: 434 GAISI 438 >gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 103 bits (257), Expect = 5e-22 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%) Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214 +C +H +R+ E FC C+C +C V Sbjct: 23 RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49 Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274 L R + + A V++L QE + A+ + +I++ +++ + Sbjct: 50 -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104 Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334 ++ L K +E++ L +E E++L K+ F++K ++L T VY + + + Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153 Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393 +D+ N+L + + QEP DP + A T +++S E P Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200 Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449 P+ P K G E + Q L+ K + S P+ST +L+T + R Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259 Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503 LL+Y LD +T H ++ LS C + S+ +P RF QVL Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313 Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560 C+ G HYWEV++Q+ VG Y S+ R+G + RLG N SWC++ ++ + A Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373 Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619 +H+ L P R+GV L+ + G + F+ V + ++ FR F E LYPA ++ Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433 Query: 620 AGATL 624 ++ Sbjct: 434 GAISI 438 >gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] Length = 432 Score = 90.5 bits (223), Expect = 4e-18 Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 5/140 (3%) Query: 480 SVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPE 539 +V+ PQ YR +RF+ SQVL G HYWEV+ + + VG+ M+R + Sbjct: 282 TVSHRPQPYRWSCERFS-TSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSR---D 337 Query: 540 SRLGRNSASWCVEWFNT-KISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVH 598 LGR S CVEW T ++SAWH E L S + VG+ LN + G + F++V ++ Sbjct: 338 QVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEK 397 Query: 599 LMYKFRVDFTEALYPAFWVF 618 L+Y+ + + LYPAFW++ Sbjct: 398 LLYECTISASSPLYPAFWLY 417 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Query: 9 EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS-PYLCPQCRAVYQARPQLHKNT 67 ++L C IC P T PCGH+FC CL W + + + CP CR +P L KNT Sbjct: 17 DDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKNT 76 Query: 68 VLCNVVEQFLQADLAREPPADVWTPPARASAPSPNA 103 +L ++ +++ +A ARE A + PA P ++ Sbjct: 77 LLQDLADKYRRA--AREIQAG--SDPAHCPCPGSSS 108 >gi|22749269 ring finger protein 129 [Homo sapiens] Length = 471 Score = 85.9 bits (211), Expect = 1e-16 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 19/227 (8%) Query: 417 QAGLEAAAKATSSHPNSTSLKAKVLETF-LAKSRPELLEYY-----------IKVILDYN 464 Q+ LE +A S H +LK L +F L K L Y + VILD N Sbjct: 243 QSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQVDVILDLN 302 Query: 465 TAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFC 524 TAH ++ +SE +N P+RF C VLG + G HYWEVE+ Sbjct: 303 TAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKW 362 Query: 525 GVGICYGSM--NRQGPESRLGRNSASWCV-EWFNTKISAWHNNVEKTLPSTKATRVGVLL 581 +G+C + N Q S LG W + + + A + LP K +++G+ L Sbjct: 363 ILGVCQDCLLRNWQDQPSVLG---GFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFL 419 Query: 582 NCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICS 628 + + G + F+ + D+ ++Y F FTEA++P F+ + L ICS Sbjct: 420 DYELGDLSFYNMNDR-SILYTFNDCFTEAVWPYFYTGTDSEPLKICS 465 Score = 67.4 bits (163), Expect = 4e-11 Identities = 70/311 (22%), Positives = 120/311 (38%), Gaps = 62/311 (19%) Query: 4 LCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQL 63 L L EE SC ICLE K+PVT CGHNFC SCL+ +W + CP CR + + Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYK-SF 65 Query: 64 HKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCM 123 +N L N+ E Q + R ++ NA C K T Sbjct: 66 RRNPQLRNLTEIAKQLQIRR----------SKRKRQKENAM-----CEKHNQFLTL---- 106 Query: 124 ASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEH 183 FC + L ++L +CS F +H +H Sbjct: 107 --FCVKDL-------------------EILCTQCS--------FSTKHQ---------KH 128 Query: 184 KTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQ 243 C + +A++ L L + + I + + ++ +++ K E++ Sbjct: 129 YIC---PIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINS 185 Query: 244 EYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRD 303 E+ +++ L + R+I++EE + +K + L S ++ L E+E + + Sbjct: 186 EFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVE-GKSVQS 244 Query: 304 EFEFLEKASKL 314 E L +A + Sbjct: 245 NLELLTQAKSM 255 >gi|89886468 fibronectin type III and SPRY domain containing 1-like isoform 1 [Homo sapiens] Length = 498 Score = 82.0 bits (201), Expect = 1e-15 Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%) Query: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537 SV P R RFT S VLG + G HYWEV+ QK+ VG+ Y ++ G Sbjct: 320 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 376 Query: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594 +LG+ + SWC+ W +A HNN K L T ++GV + D G + F+ Sbjct: 377 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 436 Query: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625 K L+Y F+ FT+ + P F V+ G +LS Sbjct: 437 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 466 >gi|223718222 fibronectin type III and SPRY domain containing 1-like isoform 3 [Homo sapiens] Length = 530 Score = 82.0 bits (201), Expect = 1e-15 Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%) Query: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537 SV P R RFT S VLG + G HYWEV+ QK+ VG+ Y ++ G Sbjct: 352 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 408 Query: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594 +LG+ + SWC+ W +A HNN K L T ++GV + D G + F+ Sbjct: 409 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 468 Query: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625 K L+Y F+ FT+ + P F V+ G +LS Sbjct: 469 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 498 Score = 30.8 bits (68), Expect = 3.9 Identities = 33/190 (17%), Positives = 80/190 (42%), Gaps = 7/190 (3%) Query: 180 LVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239 L+ + T P S++ + L+ ++ + ++ + +D + + + V+ ++ + Sbjct: 22 LISNITIGPESINLQ----QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILS 77 Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299 +L +E+ + ++LD + + IK+E+ R + + + + L E +SL Sbjct: 78 ELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSL 137 Query: 300 TKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNE--LKQCIGRLQE 357 ++ EF + A +++ T + L K+ + +D E + Q + L Sbjct: 138 DIKEPEEFSKAARQIKDRVTMASAF-RLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPV 196 Query: 358 PTPSSGDPGE 367 P DP E Sbjct: 197 PKAPEIDPVE 206 >gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo sapiens] Length = 500 Score = 81.3 bits (199), Expect = 3e-15 Identities = 71/294 (24%), Positives = 127/294 (43%), Gaps = 44/294 (14%) Query: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKN 66 + EEL+C ICL+ F++PV+ CGHNFC CL+ WA G P+ CP+CR A L N Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHP-SAPAALRPN 64 Query: 67 TVLCNVVEQFLQADLAREPP---ADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCM 123 L + E+ + L PP W P ++ C+ + CLVC Sbjct: 65 WALARLTEKTQRRRLGPVPPGLCGRHWEP----------LRLFCE----DDQRPVCLVCR 110 Query: 124 ASFCQEHLQPHFDSP---AFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180 S QEH Q H +P AF+ S + E + + L Sbjct: 111 ES--QEH-QTHAMAPIDEAFE----------------SYRTGNFDIHVDEWKRRLIRLLL 151 Query: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240 K L ++ +L A ++ + + ++ A++ D +++++ + ++ Sbjct: 152 YHSK--QEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 209 Query: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLK--KKSEIQTLK 292 L +E L+ E + +K+ E ++N ++ +++L+ +KS+ TL+ Sbjct: 210 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 263 >gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] Length = 511 Score = 81.3 bits (199), Expect = 3e-15 Identities = 87/372 (23%), Positives = 138/372 (37%), Gaps = 81/372 (21%) Query: 2 AELCPLAEEL----SCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS----------- 46 AE LA EL +CSICLE F+EPV+ CGH+FC +C+ W G+ Sbjct: 14 AEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPP 73 Query: 47 -PYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQV 105 P CPQCR PAR S PN Q+ Sbjct: 74 FPLPCPQCR-------------------------------------EPARPSQLRPNRQL 96 Query: 106 ACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQ--DHPLQPPVRDLLRRKCSQHNRL 163 AAV T L F PA +H Q +C QH Sbjct: 97 --------AAVATLL------------RRFSLPAAAPGEHGSQAAAARAAAARCGQHGEP 136 Query: 164 REFFCPEHSECICHIC--LVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALD 221 + +C + IC +C EH+ + L +A + + L +L V+ ++ Sbjct: 137 FKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRS 196 Query: 222 DVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQIL 281 + +++ + E++ E+ ++A L E +++E + V K + L Sbjct: 197 TEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256 Query: 282 LKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEV---ELNHKLIKGIH 338 + +++ L +I+++ K D E S L S P P E+ +K + + Sbjct: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNK-VWNVS 315 Query: 339 QSTIDLKNELKQ 350 T LK LK+ Sbjct: 316 LKTFVLKGMLKK 327 Score = 78.6 bits (192), Expect = 2e-14 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%) Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411 +GRL+E + + A + K+S + +++ + P + L T Sbjct: 235 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 294 Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466 + K + + K + + SLK VL+ L K + +L E +++ LD +TA Sbjct: 295 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 351 Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526 + ++ LS + E Q+ HP RF ++VL + G H+WEVE+ + Sbjct: 352 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 411 Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586 G+ S+ R+G + W ++ + A + L +RV V L+ + G Sbjct: 412 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 470 Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626 V F+AV D HL Y FRV+F E ++P F V S G L I Sbjct: 471 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 509 >gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo sapiens] Length = 282 Score = 80.5 bits (197), Expect = 4e-15 Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Query: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159 +V CD CL + AVK+CL CM ++C+EHLQPH + Q H L PV+D R C Sbjct: 74 EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133 Query: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEAT 201 H+ FC +CIC C EH + SL A D E + Sbjct: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEVS 175 >gi|27734883 tripartite motif family-like 2 [Homo sapiens] Length = 387 Score = 80.1 bits (196), Expect = 6e-15 Identities = 89/403 (22%), Positives = 158/403 (39%), Gaps = 50/403 (12%) Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274 G A ++ R Q++ T+ K+E + T+ E I+EEE+ Sbjct: 4 GIQEAAENYRKLFQEILNTSREKLEAAKSILTD--------EQERMAMIQEEEQNFKKMI 55 Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334 ++ Y + L+ L EE EQ+L ++ E I ++ L L+ Sbjct: 56 ESEYSMRLR------LLNEECEQNLQRQQEC------------------ISDLNLRETLL 91 Query: 335 KGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPP 394 + +L+ ++ + RL + + + A + R + K+ E +K Sbjct: 92 NQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEG 151 Query: 395 PVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLE 454 + L + + + L+ L+ + H S +VL+ L Sbjct: 152 TLALLKNAKYSLERSKSLL-LEHLEPAHITDLSLCHIRGLSSMFRVLQRHLT-------- 202 Query: 455 YYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYW 514 LD TAH +ALSE + Q+ +P+R + + VL + G HYW Sbjct: 203 ------LDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYW 256 Query: 515 EVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAW-HNNVEKTLPSTK 573 EV+++K VGI +GS + +G +R T+ + W +++ K Sbjct: 257 EVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKK 316 Query: 574 ATRVGVLLNCDHGFVIFFAVADKVHLMYKF-RVDFTEALYPAF 615 VGV L+C+HG + F+ V + + L+Y F F AL P F Sbjct: 317 LDTVGVFLDCEHGQISFYNVTE-MSLIYNFSHCAFQGALRPVF 358 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 79.3 bits (194), Expect = 1e-14 Identities = 80/359 (22%), Positives = 134/359 (37%), Gaps = 78/359 (21%) Query: 2 AELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARP 61 A L L E SCS+CLE KEPV CGHNFC +C+ W Sbjct: 18 AALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE------------------- 58 Query: 62 QLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLV 121 DL R+ P V +R + PN Q+ +V Sbjct: 59 ------------------DLERDFPCPVCRKTSRYRSLRPNRQLGS------------MV 88 Query: 122 CMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV 181 +A Q ++ +RD C QH+ FC E E +C IC + Sbjct: 89 EIAKQLQA---------------VKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAI 131 Query: 182 E--HKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239 H+ + L A+ + + L+ L + ++ +R + +++ + + Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191 Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299 Q+ +E+ E+ LD + +++EEE+ + + L K+ ++ L E+E Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC 251 Query: 300 TK------RDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCI 352 + +D LEK K++ + V I E+E N + L+ LKQ I Sbjct: 252 LQSGFEMLKDVKSTLEKCEKVKTMEVTSVSI-ELEKN---FSNFPRQYFALRKILKQLI 306 Score = 79.0 bits (193), Expect = 1e-14 Identities = 65/213 (30%), Positives = 94/213 (44%), Gaps = 9/213 (4%) Query: 410 EQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKS----RPELLEYYIKVILDYNT 465 E L D+K LE K + S S++ + + + R L + V LD T Sbjct: 257 EMLKDVKST-LEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPET 315 Query: 466 AHNKVALSECYTVASVAEMPQNYRPH-PQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFC 524 AH + LSE E P P+RFT+ VL + G HYWEVE+ Sbjct: 316 AHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHW 375 Query: 525 GVGICYGSMNRQGPESRLGRNSASWCVE-WFNTKISAWHNNVEKTLPSTKATRVGVLLNC 583 VG+C S++R+G + L + W V W K +A K RVG+ L+ Sbjct: 376 AVGVCRDSVSRKGELTPL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDY 434 Query: 584 DHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616 + G + F+ V D+ H+ Y F FTE L+P F+ Sbjct: 435 EAGTLSFYNVTDRSHI-YTFTDTFTEKLWPLFY 466 >gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens] Length = 329 Score = 78.6 bits (192), Expect = 2e-14 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%) Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411 +GRL+E + + A + K+S + +++ + P + L T Sbjct: 53 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 112 Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466 + K + + K + + SLK VL+ L K + +L E +++ LD +TA Sbjct: 113 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 169 Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526 + ++ LS + E Q+ HP RF ++VL + G H+WEVE+ + Sbjct: 170 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 229 Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586 G+ S+ R+G + W ++ + A + L +RV V L+ + G Sbjct: 230 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 288 Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626 V F+AV D HL Y FRV+F E ++P F V S G L I Sbjct: 289 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 327 >gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens] Length = 303 Score = 78.6 bits (192), Expect = 2e-14 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%) Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411 +GRL+E + + A + K+S + +++ + P + L T Sbjct: 27 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86 Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466 + K + + K + + SLK VL+ L K + +L E +++ LD +TA Sbjct: 87 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143 Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526 + ++ LS + E Q+ HP RF ++VL + G H+WEVE+ + Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203 Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586 G+ S+ R+G + W ++ + A + L +RV V L+ + G Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262 Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626 V F+AV D HL Y FRV+F E ++P F V S G L I Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301 >gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens] Length = 303 Score = 78.6 bits (192), Expect = 2e-14 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%) Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411 +GRL+E + + A + K+S + +++ + P + L T Sbjct: 27 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86 Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466 + K + + K + + SLK VL+ L K + +L E +++ LD +TA Sbjct: 87 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143 Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526 + ++ LS + E Q+ HP RF ++VL + G H+WEVE+ + Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203 Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586 G+ S+ R+G + W ++ + A + L +RV V L+ + G Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262 Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626 V F+AV D HL Y FRV+F E ++P F V S G L I Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301 >gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens] Length = 303 Score = 78.6 bits (192), Expect = 2e-14 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%) Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411 +GRL+E + + A + K+S + +++ + P + L T Sbjct: 27 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86 Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466 + K + + K + + SLK VL+ L K + +L E +++ LD +TA Sbjct: 87 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143 Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526 + ++ LS + E Q+ HP RF ++VL + G H+WEVE+ + Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203 Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586 G+ S+ R+G + W ++ + A + L +RV V L+ + G Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262 Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626 V F+AV D HL Y FRV+F E ++P F V S G L I Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301 >gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo sapiens] Length = 407 Score = 77.8 bits (190), Expect = 3e-14 Identities = 56/170 (32%), Positives = 86/170 (50%), Gaps = 3/170 (1%) Query: 459 VILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518 V+LD +TAH ++ LSE Q +P+RF VLG + G HYWEVE+ Sbjct: 213 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 272 Query: 519 QKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKA-TRV 577 + VG+C S+ R+G E L + W +E F + A ++ E+ LP ++ RV Sbjct: 273 ENVMVWTVGVCRHSVERKG-EVLLIPQNGFWTLEMFGNQYRAL-SSPERILPLKESLCRV 330 Query: 578 GVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSIC 627 GV L+ + G V F+ + D+ H+ R FT + P F + S + + IC Sbjct: 331 GVFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFFRLGSDDSPIFIC 380 >gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo sapiens] Length = 523 Score = 77.8 bits (190), Expect = 3e-14 Identities = 56/170 (32%), Positives = 86/170 (50%), Gaps = 3/170 (1%) Query: 459 VILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518 V+LD +TAH ++ LSE Q +P+RF VLG + G HYWEVE+ Sbjct: 329 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 388 Query: 519 QKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKA-TRV 577 + VG+C S+ R+G E L + W +E F + A ++ E+ LP ++ RV Sbjct: 389 ENVMVWTVGVCRHSVERKG-EVLLIPQNGFWTLEMFGNQYRAL-SSPERILPLKESLCRV 446 Query: 578 GVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSIC 627 GV L+ + G V F+ + D+ H+ R FT + P F + S + + IC Sbjct: 447 GVFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFFRLGSDDSPIFIC 496 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.131 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,659,394 Number of Sequences: 37866 Number of extensions: 1339494 Number of successful extensions: 8753 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 269 Number of HSP's successfully gapped in prelim test: 434 Number of HSP's that attempted gapping in prelim test: 7468 Number of HSP's gapped (non-prelim): 1544 length of query: 630 length of database: 18,247,518 effective HSP length: 108 effective length of query: 522 effective length of database: 14,157,990 effective search space: 7390470780 effective search space used: 7390470780 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.