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Search of human proteins with 67782330
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
(1029 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 2134 0.0
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 1693 0.0
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 1662 0.0
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 606 e-173
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 573 e-163
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 539 e-153
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 66 2e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 64 6e-10
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 64 1e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 64 1e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 63 2e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 2e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 58 5e-08
gi|93141033 PAX interacting protein 1 [Homo sapiens] 55 3e-07
gi|226246533 TOX high mobility group box family member 3 isoform... 55 3e-07
gi|226054295 TOX high mobility group box family member 3 isoform... 55 3e-07
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 53 2e-06
gi|33286444 mastermind-like 2 [Homo sapiens] 52 2e-06
gi|110347429 mediator complex subunit 12 [Homo sapiens] 52 3e-06
gi|4507379 TATA box binding protein [Homo sapiens] 51 5e-06
gi|55750053 atrophin-1 [Homo sapiens] 51 5e-06
gi|55750041 atrophin-1 [Homo sapiens] 51 5e-06
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 50 8e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 50 1e-05
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 50 1e-05
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 49 2e-05
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 49 3e-05
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 49 3e-05
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 49 3e-05
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 48 4e-05
>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
Length = 1029
Score = 2134 bits (5529), Expect = 0.0
Identities = 1029/1029 (100%), Positives = 1029/1029 (100%)
Query: 1 MQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKK 60
MQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKK
Sbjct: 1 MQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKK 60
Query: 61 KKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAA 120
KKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAA
Sbjct: 61 KKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAA 120
Query: 121 RYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALL 180
RYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALL
Sbjct: 121 RYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALL 180
Query: 181 QSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMK 240
QSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMK
Sbjct: 181 QSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMK 240
Query: 241 PNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMK 300
PNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMK
Sbjct: 241 PNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMK 300
Query: 301 CSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDF 360
CSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDF
Sbjct: 301 CSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDF 360
Query: 361 NDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSL 420
NDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSL
Sbjct: 361 NDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSL 420
Query: 421 RAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQL 480
RAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQL
Sbjct: 421 RAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQL 480
Query: 481 LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPK 540
LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPK
Sbjct: 481 LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPK 540
Query: 541 PHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMME 600
PHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMME
Sbjct: 541 PHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMME 600
Query: 601 GLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPT 660
GLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPT
Sbjct: 601 GLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPT 660
Query: 661 NKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRD 720
NKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRD
Sbjct: 661 NKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRD 720
Query: 721 NTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNK 780
NTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNK
Sbjct: 721 NTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNK 780
Query: 781 MWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSV 840
MWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSV
Sbjct: 781 MWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSV 840
Query: 841 RPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALH 900
RPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALH
Sbjct: 841 RPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALH 900
Query: 901 MCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALN 960
MCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALN
Sbjct: 901 MCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALN 960
Query: 961 LFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGD 1020
LFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGD
Sbjct: 961 LFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGD 1020
Query: 1021 LLGGGSDSI 1029
LLGGGSDSI
Sbjct: 1021 LLGGGSDSI 1029
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 1693 bits (4384), Expect = 0.0
Identities = 831/903 (92%), Positives = 833/903 (92%), Gaps = 57/903 (6%)
Query: 184 SGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 243
S +A VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS
Sbjct: 931 SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 990
Query: 244 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 303
KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL
Sbjct: 991 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 1050
Query: 304 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 363
KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI
Sbjct: 1051 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 1110
Query: 364 MRKDRSGFRPPNSKDMGTTDSGPYFEK-----GGSHGLFG-------------------- 398
MRKDRSGFRPPNSKDMGTTDSGPYFEK G G
Sbjct: 1111 MRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSG 1170
Query: 399 ------------------NSTAQSRGLH--------------TPVQPLNSSPSLRAQVPP 426
N A+ G H TPVQPLNSSPSLRAQVPP
Sbjct: 1171 STLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 1230
Query: 427 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 486
QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ
Sbjct: 1231 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 1290
Query: 487 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 546
QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM
Sbjct: 1291 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 1350
Query: 547 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 606
VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA
Sbjct: 1351 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 1410
Query: 607 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 666
TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK
Sbjct: 1411 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 1470
Query: 667 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 726
SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN
Sbjct: 1471 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 1530
Query: 727 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 786
SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI
Sbjct: 1531 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 1590
Query: 787 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 846
SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL
Sbjct: 1591 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 1650
Query: 847 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 906
VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN
Sbjct: 1651 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 1710
Query: 907 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 966
TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST
Sbjct: 1711 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 1770
Query: 967 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1026
GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS
Sbjct: 1771 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1830
Query: 1027 DSI 1029
DSI
Sbjct: 1831 DSI 1833
Score = 325 bits (833), Expect = 1e-88
Identities = 185/302 (61%), Positives = 206/302 (68%), Gaps = 33/302 (10%)
Query: 38 QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 97
+EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS
Sbjct: 2 REKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 61
Query: 98 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 157
PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG
Sbjct: 62 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 121
Query: 158 AGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--- 214
AGPPPCTAPGANPNNAQVTGALLQSESGTAP + A + S WG S+ G
Sbjct: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSP 181
Query: 215 -----WGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269
W ++ G+ W P A + +S++ D A +P E+
Sbjct: 182 NPIHIWDKVIVDGSDMEEW---PCIASKDTESSSENTTDN--------NSASNPGSEKST 230
Query: 270 DGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTE 329
G +TT ++G S SAS G +C+L +D P AK + S TE
Sbjct: 231 LPG--STTSNKGKGSQCQSASSGN------ECNLGVWKSD----PKAKSVQSSN--STTE 276
Query: 330 DN 331
+N
Sbjct: 277 NN 278
Score = 45.1 bits (105), Expect = 4e-04
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 27/122 (22%)
Query: 189 VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQD 248
VW P P+ G+ ++ + GW ++ GWG+ P+ S M+
Sbjct: 633 VWDIEEVPRPE------GKSDKGTEGWESAATQTKNSGGWGDAPS--------QSNQMKS 678
Query: 249 GWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 308
GWGE W++ ++ G WN ++NS++WG GG+ K N
Sbjct: 679 GWGELSAST------EWKDPKNTGGWN------DYKNNNSSNWG-GGRPDEKTPSSWNEN 725
Query: 309 DS 310
S
Sbjct: 726 PS 727
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%)
Query: 200 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 259
+ ++ W +P + GW + + +S G G P++ N S GWG P G
Sbjct: 684 SASTEWKDPKNTG-GWNDYKNNNSSNWGGGRPDEKTPSSWNENP-SKDQGWGGGRQPNQG 741
Query: 260 --ARHPSWEEEEDGGVWNTTGSQGSASSHNSAS-WGQGGKKQMKCSLKGGN 307
+ W EE D T S +S+ S WG+GG+ ++ GGN
Sbjct: 742 WSSGKNGWGEEVD----QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
Score = 41.2 bits (95), Expect = 0.005
Identities = 68/308 (22%), Positives = 101/308 (32%), Gaps = 54/308 (17%)
Query: 148 PPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGE 207
P + G G + +P N TG ++ + W P + S+W E
Sbjct: 670 PSQSNQMKSGWGELSASTEWKDPKN---TGGWNDYKNNNSSNWGGGRPD--EKTPSSWNE 724
Query: 208 PNESSPGWG--EMDDTGAST--TGWGNTPANAPNAMKPNSKSMQ-DGWGE---------- 252
GWG + G S+ GWG N+ +S S GWGE
Sbjct: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
Query: 253 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN---------------SASWGQGGKK 297
+ G + A WE+ + WN TG Q ++ + AS GG
Sbjct: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844
Query: 298 QMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNL 357
+N SW S + ++ PS + S S+S +K D+D
Sbjct: 845 PPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSPQSIS-RKMDIDDGTSAW 896
Query: 358 GDFN-------DIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTP 410
GD N ++ K+ G P ++ T P K S A G
Sbjct: 897 GDPNSYNYKNVNLWDKNSQGGPAPREPNLPT----PMTSKSASVWSKSTPPAPDNGTSAW 952
Query: 411 VQPLNSSP 418
+P SSP
Sbjct: 953 GEPNESSP 960
Score = 32.0 bits (71), Expect = 3.1
Identities = 39/160 (24%), Positives = 60/160 (37%), Gaps = 7/160 (4%)
Query: 681 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTD--HQLLRDNTTGSNSSLNTSLPSPGA 738
P G N +P S+P P V GT+ ++TD + + +T G S S
Sbjct: 295 PGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG 354
Query: 739 WPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPP 798
+ S +H+T P +T S + NP + NK + NT+ P
Sbjct: 355 VNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNP--MENKGMPFGMGLGNTSRSTDAP 410
Query: 799 PGLT-NPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 837
T + K S S A R G T + S + ++G
Sbjct: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG 450
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 1662 bits (4305), Expect = 0.0
Identities = 816/903 (90%), Positives = 827/903 (91%), Gaps = 25/903 (2%)
Query: 145 QPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAP------ 198
QPPPP G GPPP P+N+ + SG P K P+
Sbjct: 828 QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSP 880
Query: 199 ---------DNGTSAWGEPNE---SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSM 246
D+GTSAWG+PN + + + G N P + +SKSM
Sbjct: 881 QSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSM 940
Query: 247 QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG 306
QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG
Sbjct: 941 QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG 1000
Query: 307 NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK 366
NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK
Sbjct: 1001 NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK 1060
Query: 367 DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 426
DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP
Sbjct: 1061 DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 1120
Query: 427 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 486
QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ
Sbjct: 1121 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 1180
Query: 487 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 546
QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM
Sbjct: 1181 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 1240
Query: 547 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 606
VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA
Sbjct: 1241 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 1300
Query: 607 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 666
TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK
Sbjct: 1301 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 1360
Query: 667 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 726
SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN
Sbjct: 1361 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 1420
Query: 727 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 786
SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI
Sbjct: 1421 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 1480
Query: 787 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 846
SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL
Sbjct: 1481 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 1540
Query: 847 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 906
VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN
Sbjct: 1541 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 1600
Query: 907 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 966
TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST
Sbjct: 1601 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 1660
Query: 967 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1026
GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS
Sbjct: 1661 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1720
Query: 1027 DSI 1029
DSI
Sbjct: 1721 DSI 1723
Score = 325 bits (833), Expect = 1e-88
Identities = 185/302 (61%), Positives = 206/302 (68%), Gaps = 33/302 (10%)
Query: 38 QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 97
+EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS
Sbjct: 2 REKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 61
Query: 98 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 157
PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG
Sbjct: 62 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 121
Query: 158 AGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--- 214
AGPPPCTAPGANPNNAQVTGALLQSESGTAP + A + S WG S+ G
Sbjct: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSP 181
Query: 215 -----WGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269
W ++ G+ W P A + +S++ D A +P E+
Sbjct: 182 NPIHIWDKVIVDGSDMEEW---PCIASKDTESSSENTTDN--------NSASNPGSEKST 230
Query: 270 DGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTE 329
G +TT ++G S SAS G +C+L +D P AK + S TE
Sbjct: 231 LPG--STTSNKGKGSQCQSASSGN------ECNLGVWKSD----PKAKSVQSSN--STTE 276
Query: 330 DN 331
+N
Sbjct: 277 NN 278
Score = 45.1 bits (105), Expect = 4e-04
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 27/122 (22%)
Query: 189 VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQD 248
VW P P+ G+ ++ + GW ++ GWG+ P+ S M+
Sbjct: 633 VWDIEEVPRPE------GKSDKGTEGWESAATQTKNSGGWGDAPS--------QSNQMKS 678
Query: 249 GWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 308
GWGE W++ ++ G WN ++NS++WG GG+ K N
Sbjct: 679 GWGELSAST------EWKDPKNTGGWN------DYKNNNSSNWG-GGRPDEKTPSSWNEN 725
Query: 309 DS 310
S
Sbjct: 726 PS 727
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%)
Query: 200 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 259
+ ++ W +P + GW + + +S G G P++ N S GWG P G
Sbjct: 684 SASTEWKDPKNTG-GWNDYKNNNSSNWGGGRPDEKTPSSWNENP-SKDQGWGGGRQPNQG 741
Query: 260 --ARHPSWEEEEDGGVWNTTGSQGSASSHNSAS-WGQGGKKQMKCSLKGGN 307
+ W EE D T S +S+ S WG+GG+ ++ GGN
Sbjct: 742 WSSGKNGWGEEVD----QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
Score = 39.3 bits (90), Expect = 0.019
Identities = 56/250 (22%), Positives = 84/250 (33%), Gaps = 43/250 (17%)
Query: 148 PPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGE 207
P + G G + +P N TG ++ + W P + S+W E
Sbjct: 670 PSQSNQMKSGWGELSASTEWKDPKN---TGGWNDYKNNNSSNWGGGRPD--EKTPSSWNE 724
Query: 208 PNESSPGWG--EMDDTGAST--TGWGNTPANAPNAMKPNSKSMQ-DGWGE---------- 252
GWG + G S+ GWG N+ +S S GWGE
Sbjct: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
Query: 253 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN---------------SASWGQGGKK 297
+ G + A WE+ + WN TG Q ++ + AS GG
Sbjct: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844
Query: 298 QMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNL 357
+N SW S + ++ PS + S S+S +K D+D
Sbjct: 845 PPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSPQSIS-RKMDIDDGTSAW 896
Query: 358 GDFNDIMRKD 367
GD N K+
Sbjct: 897 GDPNSYNYKN 906
Score = 32.0 bits (71), Expect = 3.1
Identities = 39/160 (24%), Positives = 60/160 (37%), Gaps = 7/160 (4%)
Query: 681 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTD--HQLLRDNTTGSNSSLNTSLPSPGA 738
P G N +P S+P P V GT+ ++TD + + +T G S S
Sbjct: 295 PGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG 354
Query: 739 WPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPP 798
+ S +H+T P +T S + NP + NK + NT+ P
Sbjct: 355 VNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNP--MENKGMPFGMGLGNTSRSTDAP 410
Query: 799 PGLT-NPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 837
T + K S S A R G T + S + ++G
Sbjct: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG 450
>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
Length = 1962
Score = 606 bits (1562), Expect = e-173
Identities = 386/945 (40%), Positives = 521/945 (55%), Gaps = 135/945 (14%)
Query: 182 SESGTAPVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAM 239
S SG W + + PA DNGTSAWG+P +S P WGE +ST+ WG++
Sbjct: 1056 SGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALS 1115
Query: 240 KPNSKSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN-------SAS 290
K KSMQDGW D P+ G R WEEEED G+WN+ SQ SS N +S
Sbjct: 1116 KSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSS 1175
Query: 291 WGQGGKKQM--KCSLKGGN--NDSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSVGSLS 344
G GKK+ + +KGGN ++W+NP KQFSN+ S E+ S+KMDLS G L
Sbjct: 1176 KGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQ 1235
Query: 345 DKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK-------------- 390
DK+ ++DK ++N+GD+N + K G RP SK+ + + PYF+K
Sbjct: 1236 DKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDKDGIVADESQNMQFM 1293
Query: 391 -----------------------------------GGSHGLFG--NSTAQSRGL-HTPVQ 412
G+ +FG N+ AQ RG+ P Q
Sbjct: 1294 SSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQ 1353
Query: 413 PLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQI 471
PL+SS P+LRAQVPP +SPQV S+LK PN+G + P PQQ+AML+QL Q+
Sbjct: 1354 PLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFGPQQVAMLNQLSQL 1407
Query: 472 PQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQ------- 522
Q QL LL QQQ+ Q+QR + R QQ+QQ R +S QQ QQ
Sbjct: 1408 NQLSQISQLQRLLAQQQR---AQSQRSVPSGNRPQQDQQ-GRPLSVQQQMMQQSRQLDPN 1463
Query: 523 ---QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP-----GYGSGFSSG 574
+Q+ P + P H K LDN++P+ P+LQ KGP P + G +S
Sbjct: 1464 LLVKQQTPPSQQQPLHQPAMKSFLDNVMPHT----TPELQ-KGPSPINAFSNFPIGLNS- 1517
Query: 575 GMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFD 634
++ M +SR ++WT+ ++ + + + N K+GAI + G SP+ +D
Sbjct: 1518 NLNVNMDMNSIKEPQSRLRKWTT-VDSISVNTSLDQNSSKHGAI-SSGFRLEESPFVPYD 1575
Query: 635 IIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD 693
+ T G GD W AKSP + SS+ +WPPEF+PG PWKG NIDPE+D
Sbjct: 1576 FMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGEPWKGYPNIDPETD 1629
Query: 694 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDN----SFT 749
PYVTPGSV+ + + + + DH LRD +GS+SSLNT+LPS AW + N +
Sbjct: 1630 PYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSS 1687
Query: 750 NVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPS-S 808
STSA+ D K TWSP + + T L++++WK + +N T RPPPGLT KP S
Sbjct: 1688 TAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLS 1745
Query: 809 PWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHG 868
W ++ R GWG D+R S+W + S R + WLVL NLTPQIDGSTLRT+CMQHG
Sbjct: 1746 TWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHG 1805
Query: 869 PLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQP 928
PL+TFHLNL G AL+RYS+K+E KAQ +LHMCVLGNTTILAEFA+++E+SRF AQ+Q
Sbjct: 1806 PLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQS 1865
Query: 929 PTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA-GGSSGADLAGAS 987
T P+ GWQSL + Q++ + + F T L W+ + G++ DL G S
Sbjct: 1866 LT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTS 1917
Query: 988 LWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1029
LWG P+YS+SLWG P+ DP + SP+P+ L D LGGG +S+
Sbjct: 1918 LWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
Score = 102 bits (253), Expect = 2e-21
Identities = 140/505 (27%), Positives = 188/505 (37%), Gaps = 135/505 (26%)
Query: 35 ESKQEKEQER---------EEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLS 84
E+K K+ ER EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+S
Sbjct: 5 EAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVS 64
Query: 85 QPTAASPIGSSPSPPVNGGNNAKRVAVPNGQP---------------------------- 116
QP A+ + S + NNAKR N QP
Sbjct: 65 QPQPANS-NNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQ 123
Query: 117 --PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA------GPPPCTAPGA 168
P A PREVPPRFR Q+HK LLKRGQ P LG
Sbjct: 124 QQPQALPRYPREVPPRFR-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQ 182
Query: 169 NPNNAQVTGALLQSE------------SGTAPVWSKST-------------------PPA 197
NN +V + QS+ S PV S S P A
Sbjct: 183 PQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSA 242
Query: 198 P-------------DNGTSAWGEPNESSPGWGEMDDTGASTTGWGN-TPANAPNAMKPNS 243
P D+ +S+ E N + G +TG G N T + N S
Sbjct: 243 PGSDPELASECMDADSASSSESERNITIMASG---NTGGEKDGLRNSTGLGSQNKFVVGS 299
Query: 244 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 303
S G G S GP G H + V + S+ +S++ +WG + S
Sbjct: 300 SSNNVGHGSSTGP-WGFSHGAIISTCQVSV-DAPESKSESSNNRMNAWG-----TVSSSS 352
Query: 304 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 363
GG N S +N SN G E+N + G + ++ + +G
Sbjct: 353 NGGLNPSTLN----SASNHGAWPVLENNGLALK----GPVGSGSSGINIQCSTIGQM--- 401
Query: 364 MRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGN--STAQSRGLHTPVQPLNSSPSLR 421
PN++ + + SG G +HG +G+ T +S T + P
Sbjct: 402 ----------PNNQSINSKVSG-----GSTHGTWGSLQETCESEVSGTQKVSFSGQPQ-- 444
Query: 422 AQVPPQFISPQVSAS-MLKQFPNSG 445
+ + P + + M PNSG
Sbjct: 445 -NITTEMTGPNNTTNFMTSSLPNSG 468
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 42/172 (24%)
Query: 205 WGEPNESSP-----------GWGEMDDTGASTTGWGNTPANA---PNAMKPN-------- 242
WGE N+ S GW E+ T + T G P N+ + KP
Sbjct: 866 WGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDP 925
Query: 243 SKSMQD-GWGESDGPVTGARHPSWEEEED-GGVWNTTGSQGS--------------ASSH 286
KS Q GWG+S PV+ P W +++D G W + G A
Sbjct: 926 PKSNQSLGWGDSSKPVSS---PDWNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE 982
Query: 287 NSASWGQGGKKQMKCSLK-GGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMD 337
W + + ++ ++ +W +P + N+ + ++ N +S+ D
Sbjct: 983 EPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSD 1034
Score = 37.4 bits (85), Expect = 0.073
Identities = 45/164 (27%), Positives = 59/164 (35%), Gaps = 35/164 (21%)
Query: 190 WSKSTPPA----PDNGTSAWGEPNESSPGWGE-MDDTG------ASTTGWGNTPANAPNA 238
W T P DNGT AWG + G +D T +S +GWG+ P A
Sbjct: 734 WDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGD-PKPALRW 792
Query: 239 MKPNSKSMQDGWGESDGPVTG-ARHPSWEE-EEDGGVWNTT------------GSQG--- 281
+ Q GW E D TG + W +E+ WN + SQG
Sbjct: 793 GDSKGSNCQGGW-EDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSV 851
Query: 282 SASSH-----NSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFS 320
SAS + + WG+ KK + S N L K S
Sbjct: 852 SASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSS 895
>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
Length = 1726
Score = 573 bits (1478), Expect = e-163
Identities = 411/995 (41%), Positives = 525/995 (52%), Gaps = 175/995 (17%)
Query: 160 PPPCTAPGANPNNAQVTGALLQS-------ESGTAPVWSKSTPPAP--DNGTSAWGEPNE 210
PPP A G N + + G + S T W + + P+ DNGT+AWG+P
Sbjct: 778 PPPHQA-GTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPS 836
Query: 211 SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEED 270
S GWG+ G P A KP SKSMQ+GWG S G WE+EE
Sbjct: 837 SGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE- 894
Query: 271 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQ 327
G VWN SQ S SS +SWG KK ++ +K G +++W M+ L KQ ++MG +
Sbjct: 895 GDVWNNAASQESTSS--CSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPRE 952
Query: 328 TED----NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTD 383
+ + + +D ++ +L +KK DVDKR + + D N + K G RPP SK+ + D
Sbjct: 953 PAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKP-LGCRPPISKE-SSVD 1010
Query: 384 SGPYFEKGG---------------------SH---------------------------- 394
+ +K G SH
Sbjct: 1011 RPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPS 1070
Query: 395 ---GLFGNS-TAQSRGL----HTPVQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNS 444
G+FGNS AQ+R + PVQPLNSS PSLRAQV PQF+SPQV A +L+ N
Sbjct: 1071 GNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNI 1129
Query: 445 GLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQ 504
GL+P L ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++R Q
Sbjct: 1130 GLNPALLT--SPINPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMR-Q 1180
Query: 505 QEQQLARMVSALQQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNAL 551
QEQQ+AR ++ LQQQ QQ QRQ P H HP K +D+ +
Sbjct: 1181 QEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQ 1240
Query: 552 NVGLPDLQTKG-----------PIPGYGSGFSSGGMDYGMVGG----KEAGTESRFKQWT 596
GLPDLQTK P+ G + MD M GG + ++SR QWT
Sbjct: 1241 TPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWT 1298
Query: 597 --SMMEGLPSVATQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIP-GDTLGGHTG 646
+ M+ LPS A+ E N K+GAI PGK+ Y ++D+I ++
Sbjct: 1299 HPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPV 1358
Query: 647 PAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGT 705
SW AKS ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T
Sbjct: 1359 AVPHSWSRAKS-DSDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPT 1416
Query: 706 ATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPD 760
+ I D + LL+ + SS N +LPS AWP YS+S +S + S + K D
Sbjct: 1417 INTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSD 1476
Query: 761 YKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRG 820
KSTWS P H LS+++WK RN+T RPPPGLTNPKPSS W + S G
Sbjct: 1477 IKSTWSSGPTSHTQASLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLG 1529
Query: 821 WGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQG 880
W S +S S WS S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG
Sbjct: 1530 W---TSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQG 1586
Query: 881 TALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAA 940
A++RYS+K+EAAKAQ +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P +
Sbjct: 1587 NAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTS 1639
Query: 941 GWQSLETGQNQSDPVGPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNY 994
WQS P L+ G S GL G W++ G G + LW G P Y
Sbjct: 1640 SWQSSSASSQ------PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQY 1690
Query: 995 SSSLWGVPTVEDPHRMGSPAP---LLPGDLLGGGS 1026
SSSLWG P+ +D +GSP P LLPGDLL G S
Sbjct: 1691 SSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGES 1725
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/200 (21%), Positives = 68/200 (34%), Gaps = 39/200 (19%)
Query: 163 CTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG----WGE- 217
C A A+ + + G+++ S + ++ + PPA + WG+ N +P WG+
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
Query: 218 MDDTGAST----------TGWGNTPANAPN-AMKPNSKSMQDGWGESDGPVTGARHPSW- 265
+ T ST +G N +P P KS G G+ P A W
Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
Query: 266 ---------------------EEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK 304
+ G WN T G++ NS + +LK
Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
Query: 305 GGNNDSWMN-PLAKQFSNMG 323
G +W + P SN G
Sbjct: 661 PGPQQNWASKPQDNNVSNWG 680
Score = 40.0 bits (92), Expect = 0.011
Identities = 55/219 (25%), Positives = 81/219 (36%), Gaps = 55/219 (25%)
Query: 199 DNGTSAWG-EPNESSPGWGEMDDT------GASTTGWGNTPANAPNAMKPNSKSMQDGWG 251
DNGT AWG ++S G+ D + +S +GW N P P A+ N+ GWG
Sbjct: 473 DNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP---PAAVPANT-----GWG 524
Query: 252 ESD-----GP------VTGARHPSWEEEEDGGVWNTTGSQ-------GSASSHNSASWGQ 293
+S+ GP ++ + + G W+ +Q G S WG
Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
Query: 294 GGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKR 353
G + S GG+ W A S +G L + N S +D D
Sbjct: 585 GQRSNPAWSAGGGD---W----ADSSSVLGHLGDGKKNGSG-------------WDADSN 624
Query: 354 AMNLGDFNDIMRKDRSGF-RPPNSKDMGTTDSGPYFEKG 391
G +ND R SG+ N+K T+ G + G
Sbjct: 625 RSGSG-WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPG 662
Score = 38.1 bits (87), Expect = 0.043
Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 42/157 (26%)
Query: 176 TGALLQSESGTAPVWSKSTPPAP----------DNG-----TSAWGEPNESSPG-----W 215
+ + +Q E W P P +NG + AWG P+ S+ W
Sbjct: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343
Query: 216 GE-------MDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 268
G+ D G +TGW + + N ++Q G G SW +
Sbjct: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNP------TVQPG---------GEHMNSWAKA 388
Query: 269 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKG 305
G + GS + +HN S G+ G + + KG
Sbjct: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG 425
>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
sapiens]
Length = 1690
Score = 539 bits (1388), Expect = e-153
Identities = 400/1000 (40%), Positives = 507/1000 (50%), Gaps = 200/1000 (20%)
Query: 143 RGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAP--DN 200
R + PPP G P PG ++ G + S T W + + P+ DN
Sbjct: 774 RVETPPPH--QAGTQLNRSPLLGPGRKVSSGW--GEMPNVHSKTENSWGEPSSPSTLVDN 829
Query: 201 GTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGA 260
GT+AWG+P S GWG+ G P A KP SKSMQ+GWG S G
Sbjct: 830 GTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWG-SGGDEMNL 888
Query: 261 RHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK--GGNNDSW-MNPLAK 317
WE+EE G VWN SQ S SS +SWG KK ++ +K G +++W M+ L K
Sbjct: 889 STSQWEDEE-GDVWNNAASQESTSS--CSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIK 945
Query: 318 QFSNMGLLSQTEDNP----SSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRP 373
Q ++MG + + + +D ++ +L +KK DVDKR + + D N + K G RP
Sbjct: 946 QLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPL-GCRP 1004
Query: 374 PNSKDMGTTDSGPYFEKGG---------------------SH------------------ 394
P SK+ + D + +K G SH
Sbjct: 1005 PISKE-SSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQ 1063
Query: 395 -------------GLFGNS-TAQSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSA 435
G+FGNS AQ+R + P VQPLNSS PSLRAQVP QF+SPQV A
Sbjct: 1064 NLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQA 1122
Query: 436 SMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQ 494
+L+ N GL+P L ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ Q
Sbjct: 1123 QLLQFAAKNIGLNPALLT--SPINPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQ 1174
Query: 495 RKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-------------PGMKHSPSHPVGPKP 541
R +S ++RQQ EQQ+AR ++ LQQQ QQ QRQ P H HP K
Sbjct: 1175 RNVSGSMRQQ-EQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKS 1233
Query: 542 HLDNMVPNALNVGLPDLQTKG-----------PIPGYGSGFSSGGMDYGMVGGKE----A 586
+D+ + GLPDLQTK P+ G + MD M GG +
Sbjct: 1234 AMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPS 1291
Query: 587 GTESRFKQWT--SMMEGLPSVATQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIP 637
++SR QWT + M+ LPS A+ E N K+GAI PGK+ Y ++D+I
Sbjct: 1292 QSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQ 1351
Query: 638 GDTLGGHTGPA-GDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 696
A SW AKS ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP V
Sbjct: 1352 NSESPASPPVAVPHSWSRAKSD-SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDV 1409
Query: 697 TPGSV-LGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTS 755
TPGSV G T + I D + LL+ +
Sbjct: 1410 TPGSVPTGPTINTTIQDVNRYLLK----------------------------------SG 1435
Query: 756 AKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAP 815
K D KSTWS P H LS+++WK RN+T RPPPGLTNPKPSS W +
Sbjct: 1436 GKLSDIKSTWSSGPTSHTQASLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA--- 1489
Query: 816 RSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHL 875
S GW S +S S WS S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHL
Sbjct: 1490 -SPLGW---TSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHL 1545
Query: 876 NLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATP 935
NLTQG A++RYS+K+EAAKAQ +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P
Sbjct: 1546 NLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP 1600
Query: 936 SAPAAGWQSLETGQNQSDPVGPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW- 989
P + WQS P L+ G S GL G W++ G G + LW
Sbjct: 1601 --PTSSWQSSSASSQ------PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWG 1649
Query: 990 GPPNYSSSLWGVPTVEDPHRMGSPAP---LLPGDLLGGGS 1026
G P YSSSLWG P+ +D +GSP P LLPGDLL G S
Sbjct: 1650 GVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGES 1689
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/200 (21%), Positives = 68/200 (34%), Gaps = 39/200 (19%)
Query: 163 CTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG----WGE- 217
C A A+ + + G+++ S + ++ + PPA + WG+ N +P WG+
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
Query: 218 MDDTGAST----------TGWGNTPANAPN-AMKPNSKSMQDGWGESDGPVTGARHPSW- 265
+ T ST +G N +P P KS G G+ P A W
Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
Query: 266 ---------------------EEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK 304
+ G WN T G++ NS + +LK
Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
Query: 305 GGNNDSWMN-PLAKQFSNMG 323
G +W + P SN G
Sbjct: 661 PGPQQNWASKPQDNNVSNWG 680
Score = 40.0 bits (92), Expect = 0.011
Identities = 55/219 (25%), Positives = 81/219 (36%), Gaps = 55/219 (25%)
Query: 199 DNGTSAWG-EPNESSPGWGEMDDT------GASTTGWGNTPANAPNAMKPNSKSMQDGWG 251
DNGT AWG ++S G+ D + +S +GW N P P A+ N+ GWG
Sbjct: 473 DNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP---PAAVPANT-----GWG 524
Query: 252 ESD-----GP------VTGARHPSWEEEEDGGVWNTTGSQ-------GSASSHNSASWGQ 293
+S+ GP ++ + + G W+ +Q G S WG
Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
Query: 294 GGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKR 353
G + S GG+ W A S +G L + N S +D D
Sbjct: 585 GQRSNPAWSAGGGD---W----ADSSSVLGHLGDGKKNGSG-------------WDADSN 624
Query: 354 AMNLGDFNDIMRKDRSGF-RPPNSKDMGTTDSGPYFEKG 391
G +ND R SG+ N+K T+ G + G
Sbjct: 625 RSGSG-WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPG 662
Score = 38.1 bits (87), Expect = 0.043
Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 42/157 (26%)
Query: 176 TGALLQSESGTAPVWSKSTPPAP----------DNG-----TSAWGEPNESSPG-----W 215
+ + +Q E W P P +NG + AWG P+ S+ W
Sbjct: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343
Query: 216 GE-------MDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 268
G+ D G +TGW + + N ++Q G G SW +
Sbjct: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNP------TVQPG---------GEHMNSWAKA 388
Query: 269 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKG 305
G + GS + +HN S G+ G + + KG
Sbjct: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG 425
Score = 32.7 bits (73), Expect = 1.8
Identities = 64/273 (23%), Positives = 90/273 (32%), Gaps = 43/273 (15%)
Query: 772 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 829
++ T N W N S NT P G T P P W+S +V WG S
Sbjct: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687
Query: 830 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 885
+ + W GG V Q D S P + + + GT+
Sbjct: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736
Query: 886 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 945
Y+ K ++M N I + T+ + + TP AG Q
Sbjct: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787
Query: 946 ETGQNQSDPVGPALNLFGG--------STGLGQWSSSAGGSSGADLAGASLWGPPNYSSS 997
N+S +GP + G S W + S+ D G + WG P S S
Sbjct: 788 ----NRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVD-NGTAAWGKPPSSGS 842
Query: 998 LWGVPTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1029
WG E P G + AP+ L S S+
Sbjct: 843 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSM 875
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 65.9 bits (159), Expect = 2e-10
Identities = 55/137 (40%), Positives = 73/137 (53%), Gaps = 22/137 (16%)
Query: 403 QSRGLHTPV-----QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 457
Q+ GL +P +PL S+ A + PQ I+PQ +L+Q LSP L
Sbjct: 69 QTSGLKSPKSSDKQRPLQVPVSV-AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---L 121
Query: 458 SPQQIAMLSQLPQIPQF------QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLAR 511
QQ A++ Q Q+ +F QL QLL QQQQQQQ Q Q++ Q +QQQ+QQ +
Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181
Query: 512 MVSALQQQQQQQQRQPG 528
QQQQQQQQ+ PG
Sbjct: 182 Q----QQQQQQQQQHPG 194
Score = 31.2 bits (69), Expect = 5.3
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 515
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235
Query: 516 LQQQ 519
LQ+Q
Sbjct: 236 LQRQ 239
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 64.3 bits (155), Expect = 6e-10
Identities = 48/113 (42%), Positives = 62/113 (54%), Gaps = 16/113 (14%)
Query: 422 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------Q 475
A + PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F Q
Sbjct: 117 AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQ 170
Query: 476 LACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 528
L QLL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 219
Score = 40.4 bits (93), Expect = 0.009
Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 19/123 (15%)
Query: 414 LNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQ 473
L S S Q P Q + P+ + G F V P +AM++ PQ
Sbjct: 73 LKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAV-----PVSVAMMTPQVITPQ 127
Query: 474 F--QLACQLLLQQQQQQQLLQNQRKISQAVRQQQE--------QQLARMVSALQQQQQQQ 523
Q+ Q +L QQ Q LLQ Q QAV QQ+ QQ + LQQQQQQQ
Sbjct: 128 QMQQILQQQVLSPQQLQALLQQQ----QAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 183
Query: 524 QRQ 526
Q+Q
Sbjct: 184 QQQ 186
Score = 31.2 bits (69), Expect = 5.3
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 515
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 202 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 260
Query: 516 LQQQ 519
LQ+Q
Sbjct: 261 LQRQ 264
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/230 (30%), Positives = 92/230 (40%), Gaps = 13/230 (5%)
Query: 306 GNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMR 365
G W + +Q L+SQ ED S D + V +A ++ ++
Sbjct: 5 GQETDWRSTAFRQ----KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 366 KDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPV----QPLNSSPSLR 421
+ FR ++K + S P L G A + G+ P Q L SL
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPM---NALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLG 117
Query: 422 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLL 481
A P +S Q P+S QL QQ+A L Q Q QFQ Q
Sbjct: 118 AMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVA-LQQQQQQQQFQQQQQAA 176
Query: 482 LQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKH 531
LQQQQQQQ Q Q + Q+ QQQ Q + + LQQQQQQQQ + H
Sbjct: 177 LQQQQQQQQ-QQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 42.7 bits (99), Expect = 0.002
Identities = 82/310 (26%), Positives = 112/310 (36%), Gaps = 47/310 (15%)
Query: 450 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 509
L + Q QQ L ++ Q+ Q Q QQQQQQQ LQ Q I Q QQ +
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 510 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 569
++ AL QQ QQ M H+ H P+P + N + P QT+ P+
Sbjct: 283 SQ---ALPQQLQQ------MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ-PLVSQAQ 332
Query: 570 GFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGA--IVAPG----- 622
G M Y K R P V Q+ + A +VAPG
Sbjct: 333 AL-PGQMLYTQPPLKFV----RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMIT 387
Query: 623 --KTRGG-------SPYNQFDIIPGDTLGGHTGP---AGDSWLPAKSPPT--NKIGSKSS 668
+GG P IP ++ P S LP S P+ ++ + S
Sbjct: 388 EALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQS 447
Query: 669 NASWP-PEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNS 727
P P QPG P N + S P +P S L + P + + +
Sbjct: 448 MPPPPQPSPQPGQP-SSQPNSNVSSGPAPSPSSFLPSPSPQP---------SQSPVTART 497
Query: 728 SLNTSLPSPG 737
N S+PSPG
Sbjct: 498 PQNFSVPSPG 507
Score = 38.9 bits (89), Expect = 0.025
Identities = 80/370 (21%), Positives = 136/370 (36%), Gaps = 76/370 (20%)
Query: 37 KQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 96
+Q+++ +R QL ++++++ +++++ Q + Q P + +P + QP P + P
Sbjct: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ----PPIQQPPMQQPQPP-PSQALP 287
Query: 97 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQ------QDHKVLLKRGQPP--- 147
+ P Q P A+ P ++PP+ + Q Q + QPP
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF 347
Query: 148 ---------PP-----------------------------SCMLLGG---GAGPPPCTAP 166
PP + GG A PP TA
Sbjct: 348 VRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAV 407
Query: 167 GANPNNAQVTG--ALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAS 224
A P+++ G + Q + P+ S +P + P + SP G+ S
Sbjct: 408 SAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNS 467
Query: 225 TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSAS 284
G PA +P++ P+ S PVT AR P G NT + S
Sbjct: 468 NVSSG--PAPSPSSFLPSPSPQ-----PSQSPVT-ARTPQNFSVPSPGPLNTPVNPSSVM 519
Query: 285 SHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLS-VGSL 343
S +S Q ++Q LK ++ PL + ++++ + N K DLS + SL
Sbjct: 520 SPAGSS--QAEEQQYLDKLK--QLSKYIEPLRR------MINKIDKNEDRKKDLSKMKSL 569
Query: 344 SDKKFDVDKR 353
D D KR
Sbjct: 570 LDILTDPSKR 579
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/230 (30%), Positives = 92/230 (40%), Gaps = 13/230 (5%)
Query: 306 GNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMR 365
G W + +Q L+SQ ED S D + V +A ++ ++
Sbjct: 5 GQETDWRSTAFRQ----KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 366 KDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPV----QPLNSSPSLR 421
+ FR ++K + S P L G A + G+ P Q L SL
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPM---NALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLG 117
Query: 422 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLL 481
A P +S Q P+S QL QQ+A L Q Q QFQ Q
Sbjct: 118 AMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVA-LQQQQQQQQFQQQQQAA 176
Query: 482 LQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKH 531
LQQQQQQQ Q Q + Q+ QQQ Q + + LQQQQQQQQ + H
Sbjct: 177 LQQQQQQQQ-QQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 44.7 bits (104), Expect = 5e-04
Identities = 73/334 (21%), Positives = 128/334 (38%), Gaps = 44/334 (13%)
Query: 37 KQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 96
+Q+++ +R QL ++++++ +++++ Q + Q P + +P + QP P + P
Sbjct: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ----PPIQQPPMQQPQPP-PSQALP 287
Query: 97 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCML--- 153
+ P Q P A+ P ++PP+ + Q L+ + Q P +
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP----LVSQAQALPGQMLYTQP 343
Query: 154 -LGGGAGPPPCTAPGANP------------NNAQVTGALLQSESGTAPVWSKSTPPAPDN 200
L P P P AQ+ +Q + P+ S +P
Sbjct: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQ 403
Query: 201 GTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGA 260
+ P + SP G+ S G PA +P++ P+ S PVT A
Sbjct: 404 TPQSMPPPPQPSPQPGQPSSQPNSNVSSG--PAPSPSSFLPSPSPQ-----PSQSPVT-A 455
Query: 261 RHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFS 320
R P G NT + S S +S Q ++Q LK ++ PL +
Sbjct: 456 RTPQNFSVPSPGPLNTPVNPSSVMSPAGSS--QAEEQQYLDKLK--QLSKYIEPLRR--- 508
Query: 321 NMGLLSQTEDNPSSKMDLS-VGSLSDKKFDVDKR 353
++++ + N K DLS + SL D D KR
Sbjct: 509 ---MINKIDKNEDRKKDLSKMKSLLDILTDPSKR 539
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 450 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 509
L + Q QQ L ++ Q+ Q Q QQQQQQQ LQ Q I Q QQ +
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 510 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTK 561
++ AL QQ QQ M H+ H P+P + N + P QT+
Sbjct: 283 SQ---ALPQQLQQ------MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 62.8 bits (151), Expect = 2e-09
Identities = 47/109 (43%), Positives = 60/109 (55%), Gaps = 16/109 (14%)
Query: 426 PQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------QLACQ 479
PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F QL Q
Sbjct: 4 PQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 57
Query: 480 LLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 528
LL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG
Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 102
Score = 41.6 bits (96), Expect = 0.004
Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 515
Q QQ Q Q Q Q Q QQQQQQQ Q Q QA QQQ+QQ + ++A
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Query: 516 ---------LQQQQQQQQR 525
LQ QQ QQQ+
Sbjct: 121 QQLVFQQQLLQMQQLQQQQ 139
Score = 31.2 bits (69), Expect = 5.3
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 515
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 85 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 143
Query: 516 LQQQ 519
LQ+Q
Sbjct: 144 LQRQ 147
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.9 bits (141), Expect = 2e-08
Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 22/120 (18%)
Query: 455 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQR---------KISQAVRQQQ 505
P+LS Q + L QL Q Q QL Q LQQQQQQQL Q Q+ + Q ++QQQ
Sbjct: 3887 PKLSAQPMGSLQQLQQ--QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQ 3944
Query: 506 EQQLARMVSALQQQQQQQQ---------RQPGMKHSPSHPVGPKPHLDNMVPNALNVGLP 556
+QQL + LQQQQQQQQ +Q G+ + + P+ V AL G+P
Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV--ALGPGMP 4002
Score = 54.7 bits (130), Expect = 4e-07
Identities = 46/131 (35%), Positives = 61/131 (46%), Gaps = 15/131 (11%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA----- 510
QL QQ+ Q Q+ Q Q Q LQQQQQQ Q Q++ Q +QQQ+QQ+
Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQ---QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 511 -RMVSALQQQQQQQQRQPGMKHSP----SHP--VGPKPHLDNMVPNALNVGLPDLQTKGP 563
++S QQQQQQ PGM P S P +GP L N ++ + T+GP
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
Query: 564 IPGYGSGFSSG 574
G + G
Sbjct: 4042 STHQGGPLAIG 4052
Score = 44.3 bits (103), Expect = 6e-04
Identities = 54/179 (30%), Positives = 77/179 (43%), Gaps = 26/179 (14%)
Query: 390 KGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPG 449
+G G G G+ P QP P L + Q + P+ G PG
Sbjct: 3645 QGPPGGQAGGLRLTPGGMALPGQP--GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
Query: 450 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 509
L+ + + S+L Q Q QL QQQ+ QL Q K+ Q +QQQ+QQ
Sbjct: 3703 ------NLALRSLGPDSRLLQERQLQL-------QQQRMQLAQ---KLQQQQQQQQQQQH 3746
Query: 510 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 568
A+QQQQQQ PG++ + +GPKP ++P + + GL +Q P P G
Sbjct: 3747 LLGQVAIQQQQQQ---GPGVQ--TNQALGPKP--QGLMPPSSHQGLL-VQQLSPQPPQG 3797
Score = 41.6 bits (96), Expect = 0.004
Identities = 50/180 (27%), Positives = 72/180 (40%), Gaps = 36/180 (20%)
Query: 455 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVS 514
P+ +++ ++++ Q QL Q+ QQ++ L+ R +QQQ+QQ
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLD-QVRKQQKEHTNLMAEYRN-----KQQQQQQ------ 3604
Query: 515 ALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG--FS 572
QQQQQQQQ + SPS P L +P L G +GP G G +
Sbjct: 3605 --QQQQQQQQHSAVLALSPSQ----SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658
Query: 573 SGGMDY-GMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYN 631
GGM G GG T ++A Q+ H GA G + G P N
Sbjct: 3659 PGGMALPGQPGGPFLNT---------------ALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703
Score = 40.4 bits (93), Expect = 0.009
Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 11/86 (12%)
Query: 454 GPQ--LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA- 510
GPQ L P Q+A+L Q Q L Q +Q L+ R +S QQ Q L
Sbjct: 3797 GPQGMLGPAQVAVLQQ-------QHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMG 3849
Query: 511 -RMVSALQQQQQQQQRQPGMKHSPSH 535
R+V+A QQQQQQQ +Q G SH
Sbjct: 3850 HRLVTAQQQQQQQQHQQQGSMAGLSH 3875
Score = 40.0 bits (92), Expect = 0.011
Identities = 95/379 (25%), Positives = 140/379 (36%), Gaps = 41/379 (10%)
Query: 391 GGSHGLFGN--STAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSP 448
GGSHG G+ S+ S H QP S + + PQ ML++ + P
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ--QPMLERPMQNNTGP 4170
Query: 449 GLFNVGPQL-SPQQIAMLSQLPQIPQFQLACQLLL-----------QQQQQQQLLQNQRK 496
GP L S Q + + +P + Q + Q +L QQQQQ Q L QR+
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 497 I--SQAVRQQQE-QQLARMVSALQQQ---QQQQQRQPGMKHSPSHPVGPKPHLDN----- 545
+ SQAVRQ Q+ S LQ Q Q PG + P +G P
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Query: 546 MVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRF---KQWTSMMEGL 602
P AL+ G P L P P S + TE++ T +G
Sbjct: 4291 APPGALSTG-PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG- 4348
Query: 603 PSVATQEANMHKNGAIVAPGK-TRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTN 661
P++ + A +A ++G P++ P D L P S +P N
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWD-----PPDNLAETQKPEQSSLVPGHLDQVN 4403
Query: 662 -KIGSKSSNASWPPEFQPGVPWKGIQNIDPES--DPYVTPGSVLGGTATSPIVDTDHQLL 718
++ ++S S E + G Q++ E+ +P PG+ P + H LL
Sbjct: 4404 GQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLL 4463
Query: 719 RDNTTGSNSSLNTSLPSPG 737
+ N L+T S G
Sbjct: 4464 QKLLRAKNVQLSTGRGSEG 4482
Score = 33.9 bits (76), Expect = 0.81
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 411 VQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQ 470
VQ L+ P Q P + P A + +Q P + +GPQ P + +++Q
Sbjct: 3787 VQQLSPQPP---QGPQGMLGPAQVAVLQQQHPGA--------LGPQ-GPHRQVLMTQSRV 3834
Query: 471 IPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMK 530
+ QLA QQ Q L+ ++ +Q +QQQ+ Q ++ L QQ G
Sbjct: 3835 LSSPQLA-------QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887
Query: 531 HSPSHPVG 538
+ P+G
Sbjct: 3888 KLSAQPMG 3895
Score = 32.3 bits (72), Expect = 2.4
Identities = 50/194 (25%), Positives = 76/194 (39%), Gaps = 14/194 (7%)
Query: 381 TTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQ 440
T +G + G G ST +S GL +P++P PS+ P P +S ++
Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGL-SPLRP----PSVLPPPAPDGSLPYLSHGASQR 2635
Query: 441 FPNSGL-SPGLFNVGPQLSPQQIAMLSQLP--QIPQFQLACQLLLQQQQQQQLLQNQRKI 497
SG+ SP P ++LP Q P Q L++Q+Q+Q L+
Sbjct: 2636 ---SGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIR 2692
Query: 498 SQAVRQ--QQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGL 555
Q R +QE++ A + +P G P ++L VGL
Sbjct: 2693 QQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL-VGL 2751
Query: 556 PDLQTKGPIPGYGS 569
P + GPI G GS
Sbjct: 2752 PPSKLSGPILGPGS 2765
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 6/109 (5%)
Query: 146 PPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAP----DNG 201
P PP + G GP T P ++P + + L S S P ++ P P G
Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPK-RPSQLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
Query: 202 TSAWGEPNESSPGWGEMDDTGAST-TGWGNTPANAPNAMKPNSKSMQDG 249
+ P SP ++ DT S G + P N KP S+ G
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPG 4397
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 18/82 (21%)
Query: 488 QQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-----PG------MKHSPSHP 536
+ LL++++K Q++QQL+ + QQQQQQQQ+ PG + H S P
Sbjct: 3250 EDLLEHEKK-----ELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSP 3304
Query: 537 --VGPKPHLDNMVPNALNVGLP 556
G + L + A GLP
Sbjct: 3305 SLAGSQQQLSLGLAGARQPGLP 3326
Score = 31.2 bits (69), Expect = 5.3
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 32/158 (20%)
Query: 37 KQEKEQEREEQLMEDKK--RKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQP-TAASPIG 93
K ++ Q+ ++L+ +K RK++ + EA K +Q+ + +T+P+++ + +P G
Sbjct: 4521 KPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFG 4580
Query: 94 SSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCML 153
S PVN G + R A +G P+ Y ++L K PP+
Sbjct: 4581 S--GCPVN-GQSQLRGAFGSGALPTGPDYY-------------SQLLTKNNLSNPPT--- 4621
Query: 154 LGGGAGPPPCTAPGANPNNAQ---VTGALLQSESGTAP 188
PP + P P + Q V G E G P
Sbjct: 4622 -------PPSSLPPTPPPSVQQKMVNGVTPSEELGEHP 4652
Score = 30.8 bits (68), Expect = 6.9
Identities = 40/172 (23%), Positives = 59/172 (34%), Gaps = 34/172 (19%)
Query: 76 PEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAAR------YMPREVPP 129
PEV + S + G P+ G VP+GQPP+ R ++ P
Sbjct: 2475 PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPM 2534
Query: 130 RFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPV 189
RF Q +G + PP PG P + + S G P
Sbjct: 2535 RFTFPQ-----------------AVGEPSLKPPVPQPGLPPPHG------INSHFGPGPT 2571
Query: 190 WSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKP 241
K P N T A G + S G +G++ +G +P P+ + P
Sbjct: 2572 LGK---PQSTNYTVATGNFHPSGSPLG--PSSGSTGESYGLSPLRPPSVLPP 2618
Score = 30.4 bits (67), Expect = 9.0
Identities = 40/189 (21%), Positives = 55/189 (29%), Gaps = 26/189 (13%)
Query: 31 PPGEESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAAS 90
PP EE E ++ ++ E P + LS P S
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 91 PIGSSPS------PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRG 144
P+ P PP + + P PP +R P V R + L
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 145 QPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSA 204
+ P S PPP +P + P P S ++PP D S
Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPP-----------------PEDSPASPPPED---SL 715
Query: 205 WGEPNESSP 213
P E SP
Sbjct: 716 MSLPLEESP 724
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 57.8 bits (138), Expect = 5e-08
Identities = 50/217 (23%), Positives = 89/217 (41%), Gaps = 35/217 (16%)
Query: 1 MQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKK 60
+++ +G+ E S + + V G G +P ++ ++ ++E E++ E+K ++ E+K+
Sbjct: 323 LESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKE 382
Query: 61 KKEATQKVT------EQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNG 114
++ +++ E K P +T P+ S P P +SP PP+ P
Sbjct: 383 ERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPL----------CPPP 432
Query: 115 QPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQ 174
PP + +P PP + +Q+ PPP G PP T P+
Sbjct: 433 PPPVSPPPLPSPPPPPAQEEQEE-------SPPPVVPATCSRKRGRPPLT-----PSQRA 480
Query: 175 VTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNES 211
A GT +PP P T+ G P +S
Sbjct: 481 EREAARAGPEGT-------SPPTPTPSTATGGPPEDS 510
Score = 31.6 bits (70), Expect = 4.0
Identities = 53/205 (25%), Positives = 70/205 (34%), Gaps = 30/205 (14%)
Query: 70 EQKTKVPEV-TKPSLSQP-TAASPIGSSPSPPVNGGNNAKRVAVPNGQP---PSAARYMP 124
E K P+V P L P T + P+ P+P + R P P P R +
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPS----PPRAPTPPSTPVPLPEKRRSIL 604
Query: 125 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQ--- 181
RE P FR L R PPPP PPP +P P + LL+
Sbjct: 605 RE--PTFRWTS-----LTRELPPPPP------APPPPPAPSPPPAPATSSRRPLLLRAPQ 651
Query: 182 ---SESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNA 238
SE+ S TPP + EP + E + T + P AP
Sbjct: 652 FTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVV 711
Query: 239 MKPNSKSMQDGWGE--SDGPVTGAR 261
P + S+GP T A+
Sbjct: 712 TTPVKAEVSPHGAPALSNGPQTQAQ 736
Score = 31.6 bits (70), Expect = 4.0
Identities = 42/193 (21%), Positives = 59/193 (30%), Gaps = 32/193 (16%)
Query: 32 PGEESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASP 91
P EE + E + ++ E ++ PE P + P
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRP 1847
Query: 92 IGSSPSPPVNGGNNAKRVAVPN-------------------GQPPSAARYMPREVPPRFR 132
S PP + R+ VPN G P S ++P P F
Sbjct: 1848 DSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFP 1907
Query: 133 CQQDHKVLLKRGQP----PPPSCMLLGGGAGPPPCTAPGAN-PNNAQVTGALLQSESGTA 187
+R P PPPS A PP T+P P V AL + A
Sbjct: 1908 APPRRS---RRPSPLAPRPPPS-----RWASPPLKTSPQLRVPPPTSVVTALTPTSGELA 1959
Query: 188 PVWSKSTPPAPDN 200
P +PP P++
Sbjct: 1960 PPGPAPSPPPPED 1972
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 55.5 bits (132), Expect = 3e-07
Identities = 49/121 (40%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 410 PVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPG--LFNVGPQLSP--QQIAML 465
P QP + P + Q Q P + QFP L P L QL P QQ A+
Sbjct: 441 PQQPPH--PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQ 498
Query: 466 SQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQR 525
Q Q+ Q QL Q L Q QQQ LLQ Q++ +Q Q+QQL RM QQQQQQQ
Sbjct: 499 QQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ-----QQIQQQQLQRM----HQQQQQQQM 549
Query: 526 Q 526
Q
Sbjct: 550 Q 550
Score = 37.4 bits (85), Expect = 0.073
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 460 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQA-----VRQQQEQQLARMVS 514
QQ Q Q P L Q ++Q QQQQQ +Q+ Q +QQQ+QQ A
Sbjct: 403 QQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQ 462
Query: 515 ALQQQ---QQQQQRQPGMKHSPSHPVGP 539
QQQ QQQ P H P + P
Sbjct: 463 FSQQQLQFPQQQLHPPQQLHRPQQQLQP 490
Score = 37.0 bits (84), Expect = 0.096
Identities = 23/56 (41%), Positives = 26/56 (46%), Gaps = 8/56 (14%)
Query: 481 LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHP 536
+LQQQQQ Q Q Q + QQ + LQQQQQQQ Q P HP
Sbjct: 400 MLQQQQQAQQQQQQHPVLHLQPQQ--------IMQLQQQQQQQISQQPYPQQPPHP 447
Score = 36.2 bits (82), Expect = 0.16
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 9/73 (12%)
Query: 464 MLSQLPQIPQFQLACQLLLQQQQQQQ--LLQNQRKISQAVRQQQEQQLARMV-------S 514
+ SQ+ P+ + Q QQQQQQ +L Q + ++QQQ+QQ+++
Sbjct: 388 LFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHP 447
Query: 515 ALQQQQQQQQRQP 527
QQQQQQQQ P
Sbjct: 448 FSQQQQQQQQAHP 460
Score = 34.7 bits (78), Expect = 0.48
Identities = 34/98 (34%), Positives = 42/98 (42%), Gaps = 27/98 (27%)
Query: 456 QLSPQQIAMLSQ----LPQIPQFQLACQLLL-------QQQQQQQLLQNQRKISQAVRQQ 504
QL QQ+A L Q L Q Q Q+ Q L QQQ Q Q + + SQA++ Q
Sbjct: 508 QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ 567
Query: 505 QEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPH 542
Q Q QQQQQ+QP P P+ H
Sbjct: 568 VPPQ--------QPPQQQQQQQP--------PPSPQQH 589
Score = 31.6 bits (70), Expect = 4.0
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 10/89 (11%)
Query: 457 LSPQQIAMLSQ-----LPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQ---- 507
L PQQI L Q + Q P Q QQQQQQQ + Q ++ Q+Q
Sbjct: 419 LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPP 478
Query: 508 -QLARMVSALQQQQQQQQRQPGMKHSPSH 535
QL R LQ QQQ Q H
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFHQLQQH 507
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 55.1 bits (131), Expect = 3e-07
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 407 LHTPVQPLNSSPSLRAQVPPQFISPQVSA---SMLKQFPNSGLSPGLFNVGPQ--LSPQQ 461
+ P+ + +S ++ A +P +P +S+ +M+ P++ +SP + Q L QQ
Sbjct: 385 MRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ 444
Query: 462 IAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQ 521
Q+ Q+ Q QL + QQ QQQ Q+ + Q QQQ+Q L + ++ Q QQQ
Sbjct: 445 QQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 504
Query: 522 QQQR-QPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 569
QQR Q H P P + V + Q PIP GS
Sbjct: 505 LQQRLQLQQLQHMQHQSQPSPRQHSPVAS---------QITSPIPAIGS 544
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 55.1 bits (131), Expect = 3e-07
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 407 LHTPVQPLNSSPSLRAQVPPQFISPQVSA---SMLKQFPNSGLSPGLFNVGPQ--LSPQQ 461
+ P+ + +S ++ A +P +P +S+ +M+ P++ +SP + Q L QQ
Sbjct: 390 MRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ 449
Query: 462 IAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQ 521
Q+ Q+ Q QL + QQ QQQ Q+ + Q QQQ+Q L + ++ Q QQQ
Sbjct: 450 QQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 509
Query: 522 QQQR-QPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 569
QQR Q H P P + V + Q PIP GS
Sbjct: 510 LQQRLQLQQLQHMQHQSQPSPRQHSPVAS---------QITSPIPAIGS 549
>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
Length = 677
Score = 52.8 bits (125), Expect = 2e-06
Identities = 59/166 (35%), Positives = 71/166 (42%), Gaps = 31/166 (18%)
Query: 403 QSRGLHTPV----QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLS 458
Q GL +P QP P A + PQ I+PQ +L+Q LS
Sbjct: 77 QVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQ--------------QVLS 122
Query: 459 PQQIAMLSQLPQ---IPQFQLACQLLLQQQQ-QQQLLQNQRKISQAVRQQQ--EQQLARM 512
PQQ+ +L Q Q + Q QL QQ+Q Q QLLQ Q Q QQQ QQLA
Sbjct: 123 PQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQ 182
Query: 513 VSALQQQQQQQ------QRQPGMKHSPSHPVGP-KPHLDNMVPNAL 551
LQ QQ QQ QRQ + P P P +P M+P L
Sbjct: 183 QQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTEL 228
Score = 33.1 bits (74), Expect = 1.4
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 466 SQLPQIPQFQLACQLLLQQQQQQQL--LQNQRKISQAVRQQQEQQLARMVSALQQQQQQQ 523
+Q Q Q+A QLLLQQQQQQQ+ L++ ++ + Q +A M + QQ Q
Sbjct: 54 AQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ 113
Query: 524 Q 524
Q
Sbjct: 114 Q 114
Score = 31.6 bits (70), Expect = 4.0
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 477 ACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQP 527
A L QQQQQQ LQ R++ ++QQQ+QQ++ + S + +Q + P
Sbjct: 48 AADLAHAQQQQQQALQVARQL--LLQQQQQQQVSGLKSPKRNDKQPALQVP 96
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/155 (32%), Positives = 70/155 (45%), Gaps = 26/155 (16%)
Query: 428 FISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQ 487
F S Q + M P+ P L + Q QQ Q Q Q Q QQQQQ
Sbjct: 562 FNSDQANQQMPSVLPSQN-KPSLLHYTQQQQQQQ--------QQQQQQQQQQQQQQQQQQ 612
Query: 488 QQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKH--------------SP 533
QQ Q Q++ S + +QQQ+QQ + +SA QQQQQQQQ+Q + P
Sbjct: 613 QQQQQQQQQSSISAQQQQQQQSS--ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670
Query: 534 SHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 568
+ + +P L + +P + L +Q + PI G G
Sbjct: 671 AQSLPSQPLLRSPLPLQQKLLLQQMQNQ-PIAGMG 704
Score = 48.5 bits (114), Expect = 3e-05
Identities = 31/83 (37%), Positives = 41/83 (49%)
Query: 442 PNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAV 501
P G + LF+ + QQ+ + P Q QQQQQQQ Q Q++ Q
Sbjct: 551 PRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ 610
Query: 502 RQQQEQQLARMVSALQQQQQQQQ 524
+QQQ+QQ + S QQQQQQQ
Sbjct: 611 QQQQQQQQQQQSSISAQQQQQQQ 633
Score = 44.7 bits (104), Expect = 5e-04
Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 442 PNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAV 501
P+ + P N P Q+P + Q LL QQQQQ Q Q++ Q
Sbjct: 545 PHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQ 604
Query: 502 RQQQEQQLARMVSALQQQQQQQQRQ 526
+QQQ+QQ QQQQQQQQ+Q
Sbjct: 605 QQQQQQQ--------QQQQQQQQQQ 621
Score = 35.4 bits (80), Expect = 0.28
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 21/127 (16%)
Query: 430 SPQVSASMLKQFPNSGLSPGLFNVGPQLSPQ---------------QIAMLSQLPQIPQF 474
+P+ S M K S SPGL GP SPQ ++ S +P +PQ
Sbjct: 352 TPRPSLPMEKIVIKSEYSPGLTQ-GPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS 410
Query: 475 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 534
Q Q + L + +++S A QQ +Q A + QQ QQQ QP +
Sbjct: 411 QAQPQT---GSGASRALPSWQEVSHA--QQLKQIAANRQQHARMQQHQQQHQPTNWSALP 465
Query: 535 HPVGPKP 541
GP P
Sbjct: 466 SSAGPSP 472
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 27/143 (18%)
Query: 410 PVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLF-------------NVGPQ 456
P Q L S P LR+ +P Q ++ ++ P +G+ + N GP
Sbjct: 670 PAQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726
Query: 457 LSPQQIA--------MLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQ 505
SP + M SQ + Q + + LQ+Q Q+QQLL Q+ ++ A +
Sbjct: 727 PSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAP 786
Query: 506 EQQLARMVSALQQQQQQQQRQPG 528
+ Q+ R +S + Q+R G
Sbjct: 787 QDQINRHLSRPPPDYKDQRRNVG 809
Score = 32.0 bits (71), Expect = 3.1
Identities = 25/152 (16%), Positives = 67/152 (44%), Gaps = 21/152 (13%)
Query: 34 EESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIG 93
++ +Q+++Q++++Q + ++++++ +++++++ +Q+ + ++ Q
Sbjct: 592 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQ 651
Query: 94 SSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCM- 152
++ P+ QP A+ +P + R K+LL++ Q P + M
Sbjct: 652 QQQQQQ----QQQQQQQQPSSQP---AQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMG 704
Query: 153 -------------LLGGGAGPPPCTAPGANPN 171
++G GP P P +NPN
Sbjct: 705 YQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPN 736
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 434 SASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQN 493
S L+Q P + G Q + A+L + Q Q Q Q QQQQQQQ Q
Sbjct: 2017 SHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQ 2076
Query: 494 ----QRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPN 549
Q++ Q +RQQQ+QQ + QQQQQQQQ+Q + P P
Sbjct: 2077 YHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
Query: 550 ALNVGLPDLQ 559
GL Q
Sbjct: 2137 FQRQGLQQTQ 2146
Score = 38.9 bits (89), Expect = 0.025
Identities = 33/89 (37%), Positives = 37/89 (41%), Gaps = 17/89 (19%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQ------------ 503
Q QQI Q Q Q Q Q QQQQQQQ Q Q++ A Q
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQ 2140
Query: 504 -----QQEQQLARMVSALQQQQQQQQRQP 527
QQ+QQ A +V LQQQ Q QP
Sbjct: 2141 GLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/132 (31%), Positives = 58/132 (43%), Gaps = 17/132 (12%)
Query: 442 PNSGLSPGL------FNVGPQLSPQQIAMLSQLP-----QIPQFQLACQLLLQQQQQQQL 490
P ++PG+ G L+PQ I + L Q Q Q Q QQQQQQQ
Sbjct: 17 PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQ 76
Query: 491 LQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ------PGMKHSPSHPVGPKPHLD 544
Q Q++ Q +QQQ+QQ A +A+QQ QQ Q P + HS + P P
Sbjct: 77 QQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTT 136
Query: 545 NMVPNALNVGLP 556
+ P+ + P
Sbjct: 137 PLYPSPMTPMTP 148
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.2 bits (121), Expect = 5e-06
Identities = 168/773 (21%), Positives = 246/773 (31%), Gaps = 129/773 (16%)
Query: 62 KEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAAR 121
K + T +K +V E + P +++ + I S S N K +
Sbjct: 46 KAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTK-----------TEQ 94
Query: 122 YMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQ 181
+PR P D + L G P + + P +PG+ N++ + L Q
Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRD-IDQDNRSTSPSIYSPGSVENDSDSSSGLSQ 153
Query: 182 SESGT--APVWSKSTPPAPDNGT---SAWGEPNESSPGWGEMDDTGASTTGWGNTPANAP 236
+ P +P PD+ A EP+ S G T+ P AP
Sbjct: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
Query: 237 NAMKPNSKSMQDGWGES-DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH--------- 286
P+ + G G GP G + GG ++ G H
Sbjct: 214 ---PPHPQLYPGGTGGVLSGPPMGPK--------GGGAASSVGGPNGGKQHPPPTTPISV 262
Query: 287 -NSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSD 345
+S + G K + GGN S P L P + S L
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 346 KKFD---VDKRAMNLG--------DFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSH 394
+ AM G + + P +S PY S
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 395 GLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVG 454
+S++ S +P + PS PP S VS K S S +++ G
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPP-TSLSVSNQPPKYTQPSLPSQAVWSQG 441
Query: 455 PQLSPQQIAMLSQLPQIP-QFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 513
P P +L+ P F + Q + Q +QQQ+QQ
Sbjct: 442 PPPPPPYGRLLANSNAHPGPFPPSTGA---QSTAHPPVSTHHHHHQQQQQQQQQQ----- 493
Query: 514 SALQQQQQQQQRQPGMKHSPSHPVGPKPH------LDNMVPNALNVGLPDLQTKGPIPGY 567
QQQQQQQQ+ G P P G PH + P A++ L L+ P P +
Sbjct: 494 ---QQQQQQQQQHHGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548
Query: 568 GSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEG----------------------LPSV 605
S + Y G S +S +G +P+V
Sbjct: 549 LPPPHS-QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 606 ATQEANMHKNGAIVA--PGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKI 663
T A + A VA P + SP PG G P+ ++ A +PP K
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASP-------PGPPPYGKRAPSPGAYKTA-TPPGYKP 659
Query: 664 GSKSSNASWPPEFQPGVPWKGIQNIDPESDP-YVTPGSVLGGTATSPIVDTDHQLLRDNT 722
GS PP F+ G P G + P + P PGS G P
Sbjct: 660 GS-------PPSFRTGTP-PGYRGTSPPAGPGTFKPGSPTVGPGPLP------------- 698
Query: 723 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPT 775
+ S SLP P A P S S T + A+ +Y++ SP P +P+
Sbjct: 699 -PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAE--EYETPESPVPPARSPS 748
Score = 32.0 bits (71), Expect = 3.1
Identities = 48/231 (20%), Positives = 77/231 (33%), Gaps = 20/231 (8%)
Query: 34 EESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKV---PEVTKPSLSQPTAAS 90
++ +Q+++Q++++Q + + A E + P PSL
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP 543
Query: 91 PIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPP-RFRCQQDHKVLLKRGQPPPP 149
P G + PP + + + A PNG P S++ + C +G P P
Sbjct: 544 P-GPAHLPPPHSQVSYSQ-AGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP- 600
Query: 150 SCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPP----APDNGTSAW 205
PP T ++ + V + S +G PP AP G
Sbjct: 601 ---------FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKT 651
Query: 206 GEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGP 256
P PG TG G +P P KP S ++ G GP
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.2 bits (121), Expect = 5e-06
Identities = 168/773 (21%), Positives = 246/773 (31%), Gaps = 129/773 (16%)
Query: 62 KEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAAR 121
K + T +K +V E + P +++ + I S S N K +
Sbjct: 46 KAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTK-----------TEQ 94
Query: 122 YMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQ 181
+PR P D + L G P + + P +PG+ N++ + L Q
Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRD-IDQDNRSTSPSIYSPGSVENDSDSSSGLSQ 153
Query: 182 SESGT--APVWSKSTPPAPDNGT---SAWGEPNESSPGWGEMDDTGASTTGWGNTPANAP 236
+ P +P PD+ A EP+ S G T+ P AP
Sbjct: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
Query: 237 NAMKPNSKSMQDGWGES-DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH--------- 286
P+ + G G GP G + GG ++ G H
Sbjct: 214 ---PPHPQLYPGGTGGVLSGPPMGPK--------GGGAASSVGGPNGGKQHPPPTTPISV 262
Query: 287 -NSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSD 345
+S + G K + GGN S P L P + S L
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 346 KKFD---VDKRAMNLG--------DFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSH 394
+ AM G + + P +S PY S
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 395 GLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVG 454
+S++ S +P + PS PP S VS K S S +++ G
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPP-TSLSVSNQPPKYTQPSLPSQAVWSQG 441
Query: 455 PQLSPQQIAMLSQLPQIP-QFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 513
P P +L+ P F + Q + Q +QQQ+QQ
Sbjct: 442 PPPPPPYGRLLANSNAHPGPFPPSTGA---QSTAHPPVSTHHHHHQQQQQQQQQQ----- 493
Query: 514 SALQQQQQQQQRQPGMKHSPSHPVGPKPH------LDNMVPNALNVGLPDLQTKGPIPGY 567
QQQQQQQQ+ G P P G PH + P A++ L L+ P P +
Sbjct: 494 ---QQQQQQQQQHHGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548
Query: 568 GSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEG----------------------LPSV 605
S + Y G S +S +G +P+V
Sbjct: 549 LPPPHS-QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 606 ATQEANMHKNGAIVA--PGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKI 663
T A + A VA P + SP PG G P+ ++ A +PP K
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASP-------PGPPPYGKRAPSPGAYKTA-TPPGYKP 659
Query: 664 GSKSSNASWPPEFQPGVPWKGIQNIDPESDP-YVTPGSVLGGTATSPIVDTDHQLLRDNT 722
GS PP F+ G P G + P + P PGS G P
Sbjct: 660 GS-------PPSFRTGTP-PGYRGTSPPAGPGTFKPGSPTVGPGPLP------------- 698
Query: 723 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPT 775
+ S SLP P A P S S T + A+ +Y++ SP P +P+
Sbjct: 699 -PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAE--EYETPESPVPPARSPS 748
Score = 32.0 bits (71), Expect = 3.1
Identities = 48/231 (20%), Positives = 77/231 (33%), Gaps = 20/231 (8%)
Query: 34 EESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKV---PEVTKPSLSQPTAAS 90
++ +Q+++Q++++Q + + A E + P PSL
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP 543
Query: 91 PIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPP-RFRCQQDHKVLLKRGQPPPP 149
P G + PP + + + A PNG P S++ + C +G P P
Sbjct: 544 P-GPAHLPPPHSQVSYSQ-AGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP- 600
Query: 150 SCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPP----APDNGTSAW 205
PP T ++ + V + S +G PP AP G
Sbjct: 601 ---------FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKT 651
Query: 206 GEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGP 256
P PG TG G +P P KP S ++ G GP
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 50.4 bits (119), Expect = 8e-06
Identities = 48/162 (29%), Positives = 70/162 (43%), Gaps = 18/162 (11%)
Query: 415 NSSPSLRAQVPP-----QFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQL 468
N+ LR Q+ QF++ A LK + P +G G + P + PQQ + +Q+
Sbjct: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAG---GAAVMRPMMQPQQGFLNAQM 1221
Query: 469 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 528
+L QQ+ + Q Q++ Q +QQQ+QQ QQQQQQQQ+Q
Sbjct: 1222 VAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQT 1273
Query: 529 MKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG 570
SP V P +D ++ P Q P YG G
Sbjct: 1274 QAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQ-PNYGMG 1314
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/81 (39%), Positives = 45/81 (55%), Gaps = 15/81 (18%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQ---------- 505
QL PQQ+ +L Q + QL QQ Q+QQ+LQ Q ++ Q V++QQ
Sbjct: 158 QLQPQQVQEQQRLQQQQE-----QLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 506 EQQLARMVSALQQQQQQQQRQ 526
+QQL + LQQQQ QQQ++
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQE 233
Score = 46.6 bits (109), Expect = 1e-04
Identities = 31/70 (44%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 460 QQIAMLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQEQQLARMVSAL 516
Q+ +L Q Q+ Q QLL QQQ QQQQLLQ Q ++ Q QQQ++QL + L
Sbjct: 183 QEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLL 242
Query: 517 QQQQQQQQRQ 526
QQQ Q +Q
Sbjct: 243 LLQQQGQLQQ 252
Score = 45.4 bits (106), Expect = 3e-04
Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 16/102 (15%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ----------QQQLLQNQR-KISQAVRQQ 504
QL QQ+ + Q QFQ + L QQQQ QQQLLQ Q+ ++ Q + +Q
Sbjct: 210 QLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQ 269
Query: 505 QEQQLARMV-----SALQQQQQQQQRQPGMKHSPSHPVGPKP 541
Q+ QL + + LQQQQQQQ Q + + P P
Sbjct: 270 QQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPP 311
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/83 (43%), Positives = 45/83 (54%), Gaps = 14/83 (16%)
Query: 457 LSPQQIAMLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQEQQLARMV 513
L QQ + QL Q Q QL QLL QQQ QQQ LLQ Q ++ +QQQ+QQL
Sbjct: 243 LLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQL----QQQQQQQLL--- 295
Query: 514 SALQQQQQQQQRQPGMKHSPSHP 536
QQQQ+Q +Q ++ P P
Sbjct: 296 ----QQQQEQLQQQQLQPPPLEP 314
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/153 (34%), Positives = 65/153 (42%), Gaps = 25/153 (16%)
Query: 385 GPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNS 444
GP GGS G ++S+ P Q NSSP A +S V AS + +
Sbjct: 38 GPDTLSGGSGG------SESQEEEEP-QERNSSPQRPA------VSAPVGASEIAEETRP 84
Query: 445 GLSP-GLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQ 503
G L + Q PQQ QL Q PQ L Q QQ QQQL Q Q++ Q+V
Sbjct: 85 GQRELQLQQLEQQPEPQQQPQHEQLQQ-PQPHLELQQQPQQDGQQQLSQLQQEKHQSVHH 143
Query: 504 Q----------QEQQLARMVSALQQQQQQQQRQ 526
Q Q+QQL QQ+ QQQQ Q
Sbjct: 144 QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/71 (45%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 460 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQ----EQQLARMVSA 515
QQ QL Q Q QL Q LLQQQ+Q Q Q Q++ Q +QQQ +QQ
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL 254
Query: 516 LQQQQQQQQRQ 526
LQQQQ Q Q+Q
Sbjct: 255 LQQQQAQLQQQ 265
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 13/90 (14%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQEQQLARM 512
QL QQ +L Q Q QL QLL QQQ QQQ L Q Q ++ Q + QQ++QL +
Sbjct: 234 QLQQQQQLLLLQ----QQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQ 289
Query: 513 VSALQQQQ--QQQQRQPGMKHSPSHPVGPK 540
QQQQ QQQQ Q + P+ P+
Sbjct: 290 ----QQQQLLQQQQEQLQQQQLQPPPLEPE 315
Score = 39.3 bits (90), Expect = 0.019
Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 469 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQ 524
P++ QL QQ Q+QQ LQ Q++ Q +Q QEQQ+ + LQQQ Q+QQ
Sbjct: 148 PELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ-TQQAQEQQVLQQQEQLQQQVQEQQ 202
Score = 38.1 bits (87), Expect = 0.043
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQ------------LLQNQRKISQAVRQ 503
Q+ QQ+ Q Q L Q LQQQQ QQ LLQ Q ++ Q + Q
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 504 QQEQQLARMVSALQQQQQQQQ 524
QQ+ QL + + QQ Q QQQ
Sbjct: 257 QQQAQLQQQLLEQQQAQLQQQ 277
Score = 37.4 bits (85), Expect = 0.073
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 10/80 (12%)
Query: 455 PQLSPQQIAMLSQLPQ-----IPQFQLACQLLLQQQQQQ---QLLQNQRKISQAVRQQQE 506
PQ QQ LSQL Q + +L +L L QQQQ Q +Q Q+++ Q Q Q
Sbjct: 122 PQQDGQQ--QLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQT 179
Query: 507 QQLARMVSALQQQQQQQQRQ 526
QQ QQ+Q QQQ Q
Sbjct: 180 QQAQEQQVLQQQEQLQQQVQ 199
Score = 36.2 bits (82), Expect = 0.16
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 6/71 (8%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 515
+L P+ + ++ Q Q+ Q+ Q LQQQQ+Q LQ Q+ Q V QQQEQ L + V
Sbjct: 145 ELKPE-LQLMHQQQQLQPQQVQEQQRLQQQQEQ--LQTQQAQEQQVLQQQEQ-LQQQVQ- 199
Query: 516 LQQQQQQQQRQ 526
+QQ QQQ++
Sbjct: 200 -EQQLLQQQQE 209
Score = 33.1 bits (74), Expect = 1.4
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 414 LNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFN-VGPQLSPQQIAMLSQLPQIP 472
L L+ Q Q + Q +Q L P V +L P + +L Q
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 473 QFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQP 527
Q Q L +QQ+Q+QL Q K+ + + QQ EQQL + L+QQ+ Q + P
Sbjct: 340 QELERQQELERQQEQRQL---QLKLQEEL-QQLEQQLEQQQQQLEQQEVQLELTP 390
Score = 31.2 bits (69), Expect = 5.3
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 17/91 (18%)
Query: 456 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQ---------- 505
Q QQ +L Q Q+ Q Q QLL QQQ+Q Q Q Q + +++
Sbjct: 271 QAQLQQQLLLQQQEQLQQQQQQ-QLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDL 329
Query: 506 --EQQLARMVSALQQQQ----QQQQRQPGMK 530
EQ+L + L++QQ QQ+QRQ +K
Sbjct: 330 GSEQELEQQRQELERQQELERQQEQRQLQLK 360
Score = 31.2 bits (69), Expect = 5.3
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 460 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQ 519
QQ L + ++ + Q QL L+ Q++ Q L+ Q + Q +QQE QL L Q
Sbjct: 337 QQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQ 396
Query: 520 QQQQQRQPGMKHSPSHPVGPKPHLDNMVPNA 550
QQ+ Q + PV P+ L+ +VP A
Sbjct: 397 QQEVQLE-------LTPVQPELQLE-LVPAA 419
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/250 (23%), Positives = 95/250 (38%), Gaps = 55/250 (22%)
Query: 33 GEESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAA--S 90
G E EK+ + +L+E K ++ + KK+++ + + + + +P QP
Sbjct: 81 GMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIP 140
Query: 91 PIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPP--- 147
P+ PPV G G PP MP VPP L G PP
Sbjct: 141 PMAQPGLPPVPGA---------PGMPPGIPPLMP-GVPP-----------LMPGMPPVMP 179
Query: 148 --PPSCMLLGG----GAG------------PPPCTAPGANPNNAQVTGALLQSESGTAPV 189
PP M +GG G G PPP PG P + Q+++ +AP
Sbjct: 180 GMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPP--------MTQAQAVSAP- 230
Query: 190 WSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDG 249
+ PPAP T +P + P + G T +T ++ ++ +SK++
Sbjct: 231 GILNRPPAP-TATVPAPQPPVTKPLFPSAGQMGTPVTS-SSTASSNSESLSASSKALFPS 288
Query: 250 WGESDGPVTG 259
++ V G
Sbjct: 289 TAQAQAAVQG 298
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 49.3 bits (116), Expect = 2e-05
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 30/159 (18%)
Query: 163 CTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--W---GE 217
C PG+ N GA Q G+ P P + +W P G W G
Sbjct: 1603 CVCPGSQTNGGSWGGASGQDVGGSRP------GPTNQSSAGSWDSPGSQVSGSCWTGAGA 1656
Query: 218 MDDTGASTTG-----------WGNTPANAPNAMKPNSKSMQDG---WGESDGPVTGARHP 263
+D G + W +P S+ G WG + G V G P
Sbjct: 1657 VDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARP 1716
Query: 264 SWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 302
++ GG W TG+Q S SW G + + CS
Sbjct: 1717 GPADQSSGGSWAGTGNQSS-----GRSWIGPGDQAVDCS 1750
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/176 (25%), Positives = 63/176 (35%), Gaps = 16/176 (9%)
Query: 155 GGGAGPPPCTAPGANPN--NAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESS 212
G AG + G+ P N G A SK P +G S ++ S
Sbjct: 1467 GAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQIS 1526
Query: 213 PGW--GEMDDT-GASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269
G+ G +D G S TG G+ + P + + S + W ++ V G ++
Sbjct: 1527 GGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQS 1586
Query: 270 DGGVWNTTGSQGS-------ASSHNSASWGQGGKKQMKCSLKGGNND----SWMNP 314
G W TG Q S S N SWG + + S G N SW +P
Sbjct: 1587 SGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSP 1642
Score = 36.2 bits (82), Expect = 0.16
Identities = 27/117 (23%), Positives = 41/117 (35%), Gaps = 7/117 (5%)
Query: 174 QVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGW--GEMDDTGASTTGWGNT 231
Q +G E W+ + A + + G N SS + G +D G + W T
Sbjct: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGS--WAGT 1399
Query: 232 PANAPNAMKPNSKSMQDG---WGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASS 285
+ KP + G W + G +G E++ G W T Q S S
Sbjct: 1400 SDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGS 1456
Score = 30.4 bits (67), Expect = 9.0
Identities = 58/247 (23%), Positives = 85/247 (34%), Gaps = 34/247 (13%)
Query: 201 GTSAWGEPNESSPGWGE--MDDTGASTTGWGNT--PANAPNAMKPNSKSMQDGWGESDGP 256
G +W ++ S G + +D + W A+ + + P +S W ++
Sbjct: 1392 GGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQ 1451
Query: 257 VTGARHPSWEEEEDGGVWNTTGSQGSASSH--------NSASW-GQGGKKQMKCSLKGGN 307
+G ++ GG W T Q S SW G GG Q K G
Sbjct: 1452 ASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGG--QAGGGSKVGP 1509
Query: 308 ND-----SWMNPLAKQFSN---MGLLSQTEDN--PSSKMDLSVGSLSDKKFDVDKRAMNL 357
D SW N Q S +G++ Q + SVG + V R
Sbjct: 1510 EDQSSGRSWANS-GDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWA 1568
Query: 358 GDFNDIMRKDRSGFRPPNSKD--MGTTD--SGPYFEKGGSH---GLFGNSTAQSRGLHTP 410
++ R G R +S D GT D SG + GS G +G ++ Q G P
Sbjct: 1569 DAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRP 1628
Query: 411 VQPLNSS 417
P N S
Sbjct: 1629 -GPTNQS 1634
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 48.5 bits (114), Expect = 3e-05
Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 34/142 (23%)
Query: 414 LNSSPS--LRAQVPPQFI-------SPQVSASMLKQF--PNSGLSPGLFNVGPQLSPQQI 462
L S P+ L +Q P F+ +PQ+ ++ + P G+ GLF P LS
Sbjct: 3295 LTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGME-GLFPYSPALSQ--- 3350
Query: 463 AMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQ 522
A++ P LL Q QQ QQ LQ +A++QQQ++QL + QQQQ+
Sbjct: 3351 ALMGLSPG--------SLLQQYQQYQQSLQ------EAIQQQQQRQLQQ-----QQQQKV 3391
Query: 523 QQRQPGMKHSPSHPVGPKPHLD 544
QQ+QP +P P P P D
Sbjct: 3392 QQQQPKASQTPVPPGAPSPDKD 3413
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 391 GGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS-PG 449
G S+G GNS++ S TP S + P S+++L Q P + P
Sbjct: 1634 GSSNGT-GNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPP 1692
Query: 450 LFN-VGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQ 508
L N +G ++ + ++ + Q QQQQQQQ Q Q++ +Q + Q Q Q
Sbjct: 1693 LGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV 1752
Query: 509 LARMVSALQQQQQQQQRQ 526
A + LQQQ Q Q
Sbjct: 1753 QAHLQQELQQQAALIQSQ 1770
Score = 34.7 bits (78), Expect = 0.48
Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 14/141 (9%)
Query: 395 GLFGNSTAQSRGLHTPVQPLN----------SSPSLRAQVPPQFISPQVSASMLKQFPNS 444
G+F N+ Q+ L T L +SPSL P +++ +
Sbjct: 3099 GMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTT 3158
Query: 445 GLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQ 504
SPGL G P ++ S P + Q QQQQQQQ Q ++ Q
Sbjct: 3159 VPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQ----QPQVQQPPPPP 3214
Query: 505 QEQQLARMVSALQQQQQQQQR 525
Q LQQQQQ++ +
Sbjct: 3215 AAQPPPTPQLPLQQQQQRKDK 3235
Score = 32.0 bits (71), Expect = 3.1
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 3 TNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKKKK 62
T E E +SK E D + P E + Q +E+Q + K E ++++
Sbjct: 2410 TAEAEELATFNSKTEAGD-------EKPKLAEAPSAQPNQTQEKQ----GQPKPELQQQE 2458
Query: 63 EATQKVTEQKTKVPE-VTKPSLSQPTAASPIGSSP----SPPVNGGNNAKRVAVPNGQPP 117
+ QK + K+P+ V+ PSL QP +P P SP + ++ + P
Sbjct: 2459 QPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQ 2518
Query: 118 SAARYMPREVPPRFRCQQ 135
A P+ +P ++C Q
Sbjct: 2519 QLANLPPQLIP--YQCDQ 2534
Score = 30.8 bits (68), Expect = 6.9
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 30 PPPGEESKQEKEQEREEQLMED-KKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTA 88
PPP + +++Q+R+++ E K+++K K K E ++K + P T ++S P
Sbjct: 3218 PPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLP 3277
Query: 89 ASPIGSSPS 97
P+
Sbjct: 3278 TMEYAVDPA 3286
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 48.5 bits (114), Expect = 3e-05
Identities = 122/576 (21%), Positives = 198/576 (34%), Gaps = 112/576 (19%)
Query: 38 QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAAS------- 90
Q+++Q++++Q + ++++++ ++++ + + + + P+ +P + PT
Sbjct: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ 320
Query: 91 -PIGSSPSPPVNGGNNA-------KRVAVPN-------GQPPSAARYMPREVPPRF---- 131
P G+ PP G K+ +P +P A P PP +
Sbjct: 321 LPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGS 380
Query: 132 -RCQQDHK---VLLKRGQPPPPSCMLLGGGAG--PPPCTAPG-ANPNNAQVTGALLQSES 184
+ Q H + GQ P L GG P P P N + A + Q
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440
Query: 185 GTAPVWSKST----PPAPDNGTSAWG-EPNESSPGWGEMDDTGASTTGWGNTPANAPNAM 239
++P +++ P P N G + SSPG M G N P PN M
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQG-------NVP---PNFM 490
Query: 240 KPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 299
+ G +S P G G N QG S + + G G Q+
Sbjct: 491 VMQQQPPNQG-PQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQL 549
Query: 300 KCSLK----GGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAM 355
+ + GG P Q Q P + M S+ +
Sbjct: 550 QANQNVQHAGGQG---AGPPQNQM-------QVSHGPPNMMQPSLMGIH----------- 588
Query: 356 NLGDFNDIMRKDRSGFRPPNSKDM-GTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPL 414
G+ N+ + SG N +M G GP + G H S Q + P
Sbjct: 589 --GNMNN-QQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ 645
Query: 415 NSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF 474
N RAQ+ PQ M+ P+ L P SPQ++ Q+
Sbjct: 646 NPMILSRAQLMPQ-------GQMMVNPPSQNLGP---------SPQRMTPPKQM------ 683
Query: 475 QLACQLLLQQQQQQQLLQNQRKISQA-VRQQQEQQLARMVSALQQQQQQQ---QRQPGMK 530
L QQ Q NQ Q V QQ + ++++ Q +QQ Q Q +
Sbjct: 684 ------LSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM 737
Query: 531 HSPSHPV-GPKPHLD-NMVPNALNVGLPDLQTKGPI 564
P+ + GP P++ NMV + L +GP+
Sbjct: 738 PGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773
Score = 47.0 bits (110), Expect = 9e-05
Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 399 NSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQ--FPNSGLSPGLFNVGPQ 456
+S+ + G + +QP P+ ++ + P +S ++Q P+ L+P + P
Sbjct: 191 SSSMMAPGPNPELQPRTPRPASQSDA----MDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246
Query: 457 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 516
+Q+ + PQ+ Q Q Q QQQQQQQ Q Q+++ QQ +QQ + +
Sbjct: 247 SVNRQMNP-ANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQ 305
Query: 517 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPG 566
Q PG PS + P P ++ N G K P+PG
Sbjct: 306 FTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQG----WKKAPLPG 351
Score = 36.6 bits (83), Expect = 0.13
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 33/132 (25%)
Query: 415 NSSPSLR--AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIP 472
NS P L + PP + S V L+Q P PQ + ++ PQ P
Sbjct: 958 NSGPKLPEFSNRPPGYPSQPVEQRPLQQMP----------------PQLMQHVAPPPQPP 1001
Query: 473 QFQLACQLLLQQQQQQQLLQNQRKI--SQAVRQQQEQQLARMVSALQQQQQQQQ-RQPGM 529
Q QQ Q QL Q Q+ SQ QQQ+QQ +M+ L QQ + R P
Sbjct: 1002 Q----------QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS 1051
Query: 530 K--HSPSHPVGP 539
+ H P P+ P
Sbjct: 1052 QNVHPPRGPLNP 1063
Score = 33.5 bits (75), Expect = 1.1
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 53 KRKKEDKKKKEATQKVTEQKTK---VPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRV 109
K+KK +KKK + Q + T+ + E +P L + S P P
Sbjct: 915 KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP 974
Query: 110 AVPNGQPPSAARYMPREV------PPRFRCQQDHKVLLKRGQPPPPS 150
+ P Q P + MP ++ PP+ QQ L ++ QPPPPS
Sbjct: 975 SQPVEQRP--LQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS 1019
Score = 32.3 bits (72), Expect = 2.4
Identities = 60/249 (24%), Positives = 95/249 (38%), Gaps = 56/249 (22%)
Query: 30 PPPGEESKQEKEQEREEQLMEDKKRKKEDKK-KKEATQKVTEQKTKV-PEVTKPSLSQ-- 85
PPP + + +++Q++++Q+M +++ K + +Q V + + P+ + + Q
Sbjct: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSG 1074
Query: 86 --PTAAS---PIGSSPSP-------PVN---GGNNAKRVAVPNGQPPSAA-----RYMPR 125
P S P PSP PVN G N+ K V + Q PS++ +P
Sbjct: 1075 SVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPE 1134
Query: 126 -------EVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTA-PGANPNNAQVTG 177
VP H VL P M+ G GP P +A GA P V
Sbjct: 1135 ASGSEAPSVPGGPNNMPSHVVL------PQNQLMMTGPKPGPSPLSATQGATPQQPPV-N 1187
Query: 178 ALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPN 237
+L S P + T TS PN +SP + TP N P
Sbjct: 1188 SLPSSHGHHFPNVAAPTQ------TSRPKTPNRASP-----------RPYYPQTPNNRPP 1230
Query: 238 AMKPNSKSM 246
+ +P+ S+
Sbjct: 1231 STEPSEISL 1239
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 48.5 bits (114), Expect = 3e-05
Identities = 65/236 (27%), Positives = 92/236 (38%), Gaps = 54/236 (22%)
Query: 1 MQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQE---KEQEREEQLMEDKKRK-- 55
M NE EV + EQ + + + H + E+ ++E K QE+EE + K K
Sbjct: 438 MLVNENEVKQWK----EQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEK 493
Query: 56 --KEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPN 113
KE + K+ Q+V + ++ E LS+ + I PSP GG P+
Sbjct: 494 LEKETTEHKQVKQQVADLTAQLHE-----LSRRAVCASIPGGPSPGAPGG------PFPS 542
Query: 114 GQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNA 173
P S +P PP L G PPP L GG PPP P
Sbjct: 543 SVPGS---LLPPPPPPP----------LPGGMLPPPPPPLPPGGPPPPPGPPP------- 582
Query: 174 QVTGALLQSESGTAPV---WSKSTPPAPDNGTSA--WGE-PNESSPG--WGEMDDT 221
GA++ AP+ K + P P N + W + P G W E+DDT
Sbjct: 583 --LGAIMPPPG--APMGLALKKKSIPQPTNALKSFNWSKLPENKLEGTVWTEIDDT 634
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 48.1 bits (113), Expect = 4e-05
Identities = 37/116 (31%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
Query: 455 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVS 514
PQ+S QQ + +Q+ +L QQ+ + Q Q++ Q +QQQ+QQ
Sbjct: 1212 PQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ------ 1265
Query: 515 ALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG 570
QQQQQQQQ+Q SP V P +D ++ P Q P YG G
Sbjct: 1266 --QQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQ-PNYGMG 1318
Score = 30.4 bits (67), Expect = 9.0
Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 28/151 (18%)
Query: 403 QSRGLHTPVQPLNSSPS-----LRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 457
Q GL+ P P L+ Q P F S + FP G+ P + P+
Sbjct: 1106 QKAGLYGQTYPAQGPPMQGGFHLQGQ-SPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRT 1164
Query: 458 S-PQQIAM-LSQLPQIPQF----QLACQLLLQ----------------QQQQQQLLQNQR 495
+ P+Q+ M L Q Q QF + A +L ++ Q QQ N +
Sbjct: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQ 1224
Query: 496 KISQAVRQQQEQQLARMVSALQQQQQQQQRQ 526
++Q R+ + A+ QQQQQQ+Q
Sbjct: 1225 MVAQRSRELLSHHFRQQRVAMMMQQQQQQQQ 1255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,533,611
Number of Sequences: 37866
Number of extensions: 3165197
Number of successful extensions: 35120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 366
Number of HSP's successfully gapped in prelim test: 907
Number of HSP's that attempted gapping in prelim test: 19506
Number of HSP's gapped (non-prelim): 10075
length of query: 1029
length of database: 18,247,518
effective HSP length: 112
effective length of query: 917
effective length of database: 14,006,526
effective search space: 12843984342
effective search space used: 12843984342
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.