Search of human proteins with 66392227

Search of human proteins with 66392227

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]
         (152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]            313   3e-86
gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]            313   3e-86
gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]            313   3e-86
gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]             313   3e-86
gi|66392203 NME1-NME2 protein [Homo sapiens]                          313   3e-86
gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in...   281   1e-76
gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in ...   281   1e-76
gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]            217   3e-57
gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]             185   1e-47
gi|4505413 non-metastatic cells 5, protein expressed in (nucleos...    72   1e-13
gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]         71   4e-13
gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo sapi...    70   5e-13
gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]    70   5e-13
gi|148839372 thioredoxin domain containing 3 [Homo sapiens]            61   3e-10
gi|30023828 thioredoxin domain containing 6 [Homo sapiens]             59   2e-09
gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo sa...    29   1.4  
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat...    28   2.3  
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat...    28   2.3  
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat...    28   2.3  
gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens]        28   2.3  
gi|170016081 XRP2 protein [Homo sapiens]                               28   3.0  
gi|28827774 dual-specificity tyrosine-(Y)-phosphorylation regula...    27   6.7  
gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [H...    27   8.8  
gi|31317290 Smad ubiquitination regulatory factor 1 isoform 2 [H...    27   8.8  

>gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score =  313 bits (803), Expect = 3e-86
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
Sbjct: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
Sbjct: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152


>gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score =  313 bits (803), Expect = 3e-86
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
Sbjct: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
Sbjct: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152


>gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score =  313 bits (803), Expect = 3e-86
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
Sbjct: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
Sbjct: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152


>gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score =  313 bits (803), Expect = 3e-86
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
Sbjct: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
Sbjct: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152


>gi|66392203 NME1-NME2 protein [Homo sapiens]
          Length = 267

 Score =  313 bits (803), Expect = 3e-86
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
Sbjct: 116 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 175

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 176 FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 235

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
Sbjct: 236 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 267



 Score =  214 bits (546), Expect = 2e-56
 Identities = 103/116 (88%), Positives = 111/116 (95%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MAN ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLV +KF++ASE+ LK+HY+DLKDRPF
Sbjct: 1   MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNI 116
           F GLVKYM+SGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGR +
Sbjct: 61  FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRTM 116


>gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in
           isoform a [Homo sapiens]
          Length = 177

 Score =  281 bits (720), Expect = 1e-76
 Identities = 134/152 (88%), Positives = 144/152 (94%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MAN ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLV +KF++ASE+ LK+HY+DLKDRPF
Sbjct: 26  MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPF 85

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           F GLVKYM+SGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 86  FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 145

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSV+SAEKEI LWF PEELVDY SCA +W+YE
Sbjct: 146 DSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 177


>gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in
           isoform b [Homo sapiens]
          Length = 152

 Score =  281 bits (720), Expect = 1e-76
 Identities = 134/152 (88%), Positives = 144/152 (94%)

Query: 1   MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF 60
           MAN ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLV +KF++ASE+ LK+HY+DLKDRPF
Sbjct: 1   MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPF 60

Query: 61  FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120
           F GLVKYM+SGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
Sbjct: 61  FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS 120

Query: 121 DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152
           DSV+SAEKEI LWF PEELVDY SCA +W+YE
Sbjct: 121 DSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 152


>gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]
          Length = 169

 Score =  217 bits (552), Expect = 3e-57
 Identities = 97/148 (65%), Positives = 130/148 (87%)

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
           ERTF+A+KPDGVQR LVGEI++RFE+KGF+LVA+K ++ASEE L++HY +L++RPF+  L
Sbjct: 22  ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRL 81

Query: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVK 124
           VKYM SGPVVAMVW+GL+VV+T R ++G TNPAD+ PGTIRGDFCI+VG+N+IHGSDSV+
Sbjct: 82  VKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVE 141

Query: 125 SAEKEISLWFKPEELVDYKSCAHDWVYE 152
           SA +EI+LWF+ +EL+ ++  A  W+YE
Sbjct: 142 SARREIALWFRADELLCWEDSAGHWLYE 169


>gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]
          Length = 187

 Score =  185 bits (469), Expect = 1e-47
 Identities = 82/138 (59%), Positives = 110/138 (79%)

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
           ERT +A+KPDGVQR LVG++I+RFE++GF LV MK L+A E  L +HY DL+ +PF+P L
Sbjct: 38  ERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPAL 97

Query: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVK 124
           ++YM+SGPVVAMVWEG NVV+  R M+G T+ A++ PGTIRGDF + + RN+IH SDSV+
Sbjct: 98  IRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVE 157

Query: 125 SAEKEISLWFKPEELVDY 142
            A++EI LWF+  ELV +
Sbjct: 158 GAQREIQLWFQSSELVSW 175


>gi|4505413 non-metastatic cells 5, protein expressed in
           (nucleoside-diphosphate kinase) [Homo sapiens]
          Length = 212

 Score = 72.4 bits (176), Expect = 1e-13
 Identities = 49/142 (34%), Positives = 74/142 (52%), Gaps = 8/142 (5%)

Query: 4   LERTFIAIKPDGVQRGL-VGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFP 62
           +E+T   IKPD V +   + +II R    GF +V  + LR S E     Y++   + FFP
Sbjct: 12  VEKTLAIIKPDIVDKEEEIQDIILR---SGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFP 68

Query: 63  GLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHG 119
            L  YM+SGP+VAM+      +     +LG  N   +K   P ++R  +     RN +HG
Sbjct: 69  NLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHG 128

Query: 120 SDSVKSAEKEISLWFKPEELVD 141
           S+   +AE+EI   F PE +V+
Sbjct: 129 SNDFAAAEREIRFMF-PEVIVE 149


>gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]
          Length = 194

 Score = 70.9 bits (172), Expect = 4e-13
 Identities = 45/135 (33%), Positives = 74/135 (54%), Gaps = 4/135 (2%)

Query: 4   LERTFIAIKPDGVQRGLVGEII-KRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFP 62
           L+ T   IKPD V   L+ E + ++     F +V M+ L   +E  ++ Y + + R F+ 
Sbjct: 19  LQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQ 78

Query: 63  GLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHG 119
            LV++M SGP+ A +    + ++  R ++G T    ++   P +IRG F +   RN  HG
Sbjct: 79  RLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHG 138

Query: 120 SDSVKSAEKEISLWF 134
           SDSV SA +EI+ +F
Sbjct: 139 SDSVVSASREIAAFF 153


>gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo
           sapiens]
          Length = 340

 Score = 70.5 bits (171), Expect = 5e-13
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113

Query: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173

Query: 122 SVKSAEKEISLWF 134
           S  SA +E+ L+F
Sbjct: 174 SFASAAREMELFF 186



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263

Query: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323

Query: 123 VKSAEKEISLWFK 135
            +    E+  +FK
Sbjct: 324 PEDGLLEVQYFFK 336


>gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]
          Length = 376

 Score = 70.5 bits (171), Expect = 5e-13
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 92  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149

Query: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209

Query: 122 SVKSAEKEISLWF 134
           S  SA +E+ L+F
Sbjct: 210 SFASAAREMELFF 222



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299

Query: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359

Query: 123 VKSAEKEISLWFK 135
            +    E+  +FK
Sbjct: 360 PEDGLLEVQYFFK 372


>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
          Length = 588

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 39/139 (28%), Positives = 74/139 (53%), Gaps = 5/139 (3%)

Query: 4   LERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPG 63
           L+ T   IKP         +I+K  ++ GF L  +K +  + E +++ Y  +  + F+  
Sbjct: 450 LQSTLGLIKPHATSEQRE-QILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKD 508

Query: 64  LVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGS 120
           L++ ++ GP + M+    N V   R ++G T+P ++K   P +IR  F I   +NI+HG+
Sbjct: 509 LLEMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIRAQFGISKLKNIVHGA 568

Query: 121 DSVKSAEKEISLWFK-PEE 138
            +   A++ ++  F+ PEE
Sbjct: 569 SNAYEAKEVVNRLFEDPEE 587



 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 30/135 (22%), Positives = 73/135 (54%), Gaps = 5/135 (3%)

Query: 4   LERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPG 63
           LE+T   ++P+ +      ++++  + + F+++  + +  SE+  +    + ++  +F  
Sbjct: 315 LEKTLALLRPN-LFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNK 373

Query: 64  LVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCI-QVGRNIIHG 119
           L++ M SGP +A+V    N ++  + +LG     ++    P ++   F +  +  N ++G
Sbjct: 374 LIENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYG 433

Query: 120 SDSVKSAEKEISLWF 134
           SDS+++AE+EI  +F
Sbjct: 434 SDSLETAEREIQHFF 448



 Score = 30.8 bits (68), Expect = 0.46
 Identities = 20/61 (32%), Positives = 29/61 (47%)

Query: 11  IKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNS 70
           IKPD V    V EI ++  + GF + A      +EE +   Y  + D+  F   V +M S
Sbjct: 160 IKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVSFMTS 219

Query: 71  G 71
           G
Sbjct: 220 G 220


>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
          Length = 263

 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)

Query: 1   MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDR 58
           M + ERT     IKPD V  G   EII + ++ GF ++  +    +E  ++  Y      
Sbjct: 92  MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151

Query: 59  PFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
             F  LV +M SGP   ++    EG  +VV T R ++G  +P      +P ++R  +  +
Sbjct: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211

Query: 112 VGRNIIHGSDSVKSAEKEISLWF 134
           +  N +HGS   + A++E++L F
Sbjct: 212 MPFNAVHGSRDREDADRELALLF 234


>gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo
           sapiens]
          Length = 2261

 Score = 29.3 bits (64), Expect = 1.4
 Identities = 14/54 (25%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 44  SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPA 97
           +EE  +  Y D    P+   L+K + S P+  ++W+ L  +  G+++     PA
Sbjct: 339 TEEDAETFY-DNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPA 391


>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform a [Homo sapiens]
          Length = 629

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 11/41 (26%), Positives = 25/41 (60%)

Query: 16  VQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLK 56
           + +G  G+++K ++ +   LVA+K ++  +  L Q  I+L+
Sbjct: 117 IGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELR 157


>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform c [Homo sapiens]
          Length = 601

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 11/41 (26%), Positives = 25/41 (60%)

Query: 16  VQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLK 56
           + +G  G+++K ++ +   LVA+K ++  +  L Q  I+L+
Sbjct: 117 IGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELR 157


>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform b [Homo sapiens]
          Length = 589

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 11/41 (26%), Positives = 25/41 (60%)

Query: 16  VQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLK 56
           + +G  G+++K ++ +   LVA+K ++  +  L Q  I+L+
Sbjct: 117 IGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELR 157


>gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens]
          Length = 1462

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 79   EGLNVVK---------TGRVMLGETNPADSKPGTIRG--DFCIQVGRNIIHGSDSVKSAE 127
            +GL++V+         TG  ++G+     S+   +       I++G N+++GS  V   E
Sbjct: 1075 KGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFE 1134

Query: 128  KEISLWFKPEELVDYKSCAH 147
               +L   P++  D KS  H
Sbjct: 1135 INKALTKDPQDYPDKKSLPH 1154


>gi|170016081 XRP2 protein [Homo sapiens]
          Length = 350

 Score = 28.1 bits (61), Expect = 3.0
 Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 23  EIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLN 82
           ++I     KGF LV  K +    E  ++ +     R   P  +  +N GPV+A+ + G  
Sbjct: 252 KLIDEMVGKGFFLVQTKEVSMKAEDAQRVF-----REKAPDFLPLLNKGPVIALEFNGDG 306

Query: 83  VVKTGRVMLGE 93
            V+  ++++ E
Sbjct: 307 AVEVCQLIVNE 317


>gi|28827774 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 4 [Homo sapiens]
          Length = 520

 Score = 26.9 bits (58), Expect = 6.7
 Identities = 12/41 (29%), Positives = 23/41 (56%)

Query: 16  VQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLK 56
           + +G  G++ K  + K   LVA+K +R  +   +Q  ++LK
Sbjct: 110 IGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELK 150


>gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [Homo
           sapiens]
          Length = 757

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 10/28 (35%), Positives = 17/28 (60%)

Query: 124 KSAEKEISLWFKPEELVDYKSCAHDWVY 151
           K  +K + + F+ EE +DY   A +W+Y
Sbjct: 422 KDLKKRLMVKFRGEEGLDYGGVAREWLY 449


>gi|31317290 Smad ubiquitination regulatory factor 1 isoform 2 [Homo
           sapiens]
          Length = 731

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 10/28 (35%), Positives = 17/28 (60%)

Query: 124 KSAEKEISLWFKPEELVDYKSCAHDWVY 151
           K  +K + + F+ EE +DY   A +W+Y
Sbjct: 396 KDLKKRLMVKFRGEEGLDYGGVAREWLY 423


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,851,773
Number of Sequences: 37866
Number of extensions: 231164
Number of successful extensions: 421
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 384
Number of HSP's gapped (non-prelim): 29
length of query: 152
length of database: 18,247,518
effective HSP length: 93
effective length of query: 59
effective length of database: 14,725,980
effective search space: 868832820
effective search space used: 868832820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.