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Search of human proteins with 66346674
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346674 vacuolar protein sorting 13A isoform A [Homo
sapiens]
(3174 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 6288 0.0
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 6196 0.0
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 6063 0.0
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 6063 0.0
gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 1700 0.0
gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 1700 0.0
gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 1679 0.0
gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 1679 0.0
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 212 4e-54
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 212 4e-54
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 108 1e-22
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 108 1e-22
gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens] 74 2e-12
gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] 74 2e-12
gi|239047271 autophagy related 2A [Homo sapiens] 47 2e-04
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 43 0.004
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 42 0.013
gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Hom... 37 0.31
gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Hom... 37 0.31
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 35 0.90
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 35 1.5
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 34 2.0
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 34 2.0
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 34 2.0
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 34 2.6
gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens] 34 2.6
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 34 2.6
gi|62865621 toll-like receptor 10 precursor [Homo sapiens] 33 3.4
gi|62865618 toll-like receptor 10 precursor [Homo sapiens] 33 3.4
gi|71773110 apolipoprotein A-IV precursor [Homo sapiens] 33 4.5
>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
Length = 3174
Score = 6288 bits (16314), Expect = 0.0
Identities = 3174/3174 (100%), Positives = 3174/3174 (100%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS
Sbjct: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
Query: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ
Sbjct: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
Query: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY
Sbjct: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
Query: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
Sbjct: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
Query: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE
Sbjct: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
Query: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD
Sbjct: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
Query: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED
Sbjct: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
Query: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK
Sbjct: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
Query: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL
Sbjct: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
Query: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT
Sbjct: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
Query: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL
Sbjct: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
Query: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI
Sbjct: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
Query: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME
Sbjct: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
Query: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
Sbjct: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
Query: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK
Sbjct: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
Query: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA
Sbjct: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
Query: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN
Sbjct: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
Query: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT
Sbjct: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
Query: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA
Sbjct: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
Query: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR
Sbjct: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
Query: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW
Sbjct: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
Query: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF
Sbjct: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
Query: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI
Sbjct: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
Query: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
Sbjct: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
Query: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE
Sbjct: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
Query: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD
Sbjct: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
Query: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY
Sbjct: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
Query: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK
Sbjct: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
Query: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
Sbjct: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
Query: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL
Sbjct: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
Query: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST
Sbjct: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
Query: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW
Sbjct: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
Query: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA
Sbjct: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
Query: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE
Sbjct: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
Query: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ
Sbjct: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
Query: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR
Sbjct: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
Query: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ
Sbjct: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
Query: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD
Sbjct: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
Query: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
Sbjct: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
Query: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED
Sbjct: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
Query: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK
Sbjct: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
Query: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ
Sbjct: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
Query: 3061 MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP 3120
MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP
Sbjct: 3061 MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP 3120
Query: 3121 FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL 3174
FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL
Sbjct: 3121 FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL 3174
>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
Length = 3135
Score = 6196 bits (16075), Expect = 0.0
Identities = 3135/3174 (98%), Positives = 3135/3174 (98%), Gaps = 39/3174 (1%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS
Sbjct: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
Query: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ
Sbjct: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
Query: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY
Sbjct: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
Query: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
Sbjct: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
Query: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE
Sbjct: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
Query: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD
Sbjct: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
Query: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED
Sbjct: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
Query: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK
Sbjct: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
Query: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
SAPVSTTETEDKGDVIKKL GL
Sbjct: 1021 SAPVSTTETEDKGDVIKKL---------------------------------------GL 1041
Query: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT
Sbjct: 1042 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1101
Query: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL
Sbjct: 1102 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1161
Query: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI
Sbjct: 1162 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1221
Query: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME
Sbjct: 1222 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1281
Query: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
Sbjct: 1282 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1341
Query: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK
Sbjct: 1342 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1401
Query: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA
Sbjct: 1402 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1461
Query: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN
Sbjct: 1462 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1521
Query: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT
Sbjct: 1522 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1581
Query: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA
Sbjct: 1582 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1641
Query: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR
Sbjct: 1642 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1701
Query: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW
Sbjct: 1702 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1761
Query: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF
Sbjct: 1762 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1821
Query: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI
Sbjct: 1822 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1881
Query: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
Sbjct: 1882 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1941
Query: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE
Sbjct: 1942 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2001
Query: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD
Sbjct: 2002 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2061
Query: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY
Sbjct: 2062 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2121
Query: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK
Sbjct: 2122 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2181
Query: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
Sbjct: 2182 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2241
Query: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL
Sbjct: 2242 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2301
Query: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST
Sbjct: 2302 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2361
Query: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW
Sbjct: 2362 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2421
Query: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA
Sbjct: 2422 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2481
Query: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE
Sbjct: 2482 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2541
Query: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ
Sbjct: 2542 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2601
Query: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR
Sbjct: 2602 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2661
Query: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ
Sbjct: 2662 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2721
Query: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD
Sbjct: 2722 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2781
Query: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
Sbjct: 2782 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2841
Query: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED
Sbjct: 2842 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2901
Query: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK
Sbjct: 2902 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 2961
Query: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ
Sbjct: 2962 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3021
Query: 3061 MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP 3120
MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP
Sbjct: 3022 MLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEP 3081
Query: 3121 FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL 3174
FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL
Sbjct: 3082 FIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL 3135
>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
Length = 3095
Score = 6063 bits (15729), Expect = 0.0
Identities = 3063/3066 (99%), Positives = 3065/3066 (99%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS
Sbjct: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
Query: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ
Sbjct: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
Query: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY
Sbjct: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
Query: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
Sbjct: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
Query: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE
Sbjct: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
Query: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD
Sbjct: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
Query: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED
Sbjct: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
Query: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK
Sbjct: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
Query: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL
Sbjct: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
Query: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT
Sbjct: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
Query: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL
Sbjct: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
Query: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI
Sbjct: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
Query: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME
Sbjct: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
Query: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
Sbjct: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
Query: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK
Sbjct: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
Query: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA
Sbjct: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
Query: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN
Sbjct: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
Query: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT
Sbjct: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
Query: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA
Sbjct: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
Query: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR
Sbjct: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
Query: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW
Sbjct: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
Query: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF
Sbjct: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
Query: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI
Sbjct: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
Query: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
Sbjct: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
Query: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE
Sbjct: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
Query: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD
Sbjct: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
Query: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY
Sbjct: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
Query: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK
Sbjct: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
Query: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
Sbjct: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
Query: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL
Sbjct: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
Query: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST
Sbjct: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
Query: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW
Sbjct: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
Query: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA
Sbjct: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
Query: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE
Sbjct: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
Query: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ
Sbjct: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
Query: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR
Sbjct: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
Query: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ
Sbjct: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
Query: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD
Sbjct: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
Query: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
Sbjct: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
Query: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED
Sbjct: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
Query: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK
Sbjct: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
Query: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ
Sbjct: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
Query: 3061 MLQVME 3066
MLQ ++
Sbjct: 3061 MLQKIQ 3066
>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
Length = 3069
Score = 6063 bits (15729), Expect = 0.0
Identities = 3063/3067 (99%), Positives = 3065/3067 (99%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS
Sbjct: 541 HITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNS 600
Query: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ
Sbjct: 601 IVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQ 660
Query: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY
Sbjct: 661 DGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLY 720
Query: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
Sbjct: 721 SRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDK 780
Query: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE
Sbjct: 781 KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSE 840
Query: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD
Sbjct: 841 EEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGD 900
Query: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED
Sbjct: 901 CELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMED 960
Query: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK
Sbjct: 961 LLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEK 1020
Query: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL
Sbjct: 1021 SAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGL 1080
Query: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT
Sbjct: 1081 DSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYT 1140
Query: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL
Sbjct: 1141 DMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKEL 1200
Query: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI
Sbjct: 1201 AQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLI 1260
Query: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME
Sbjct: 1261 TIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPME 1320
Query: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
Sbjct: 1321 FILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAV 1380
Query: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK
Sbjct: 1381 VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLK 1440
Query: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA
Sbjct: 1441 MYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDA 1500
Query: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN
Sbjct: 1501 VFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKN 1560
Query: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT
Sbjct: 1561 PEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKIT 1620
Query: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA
Sbjct: 1621 TVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETA 1680
Query: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR
Sbjct: 1681 SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHR 1740
Query: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW
Sbjct: 1741 TVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPW 1800
Query: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF
Sbjct: 1801 NLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAF 1860
Query: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI
Sbjct: 1861 TEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI 1920
Query: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
Sbjct: 1921 RTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ 1980
Query: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE
Sbjct: 1981 IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPE 2040
Query: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD
Sbjct: 2041 DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWD 2100
Query: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY
Sbjct: 2101 LPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDY 2160
Query: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK
Sbjct: 2161 LNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNK 2220
Query: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
Sbjct: 2221 TGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH 2280
Query: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL
Sbjct: 2281 GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDL 2340
Query: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST
Sbjct: 2341 EQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHST 2400
Query: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW
Sbjct: 2401 VITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKW 2460
Query: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA
Sbjct: 2461 RCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2520
Query: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE
Sbjct: 2521 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2580
Query: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ
Sbjct: 2581 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2640
Query: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR
Sbjct: 2641 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2700
Query: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ
Sbjct: 2701 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQ 2760
Query: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD
Sbjct: 2761 SQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQD 2820
Query: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
Sbjct: 2821 VVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV 2880
Query: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED
Sbjct: 2881 EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDED 2940
Query: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK
Sbjct: 2941 YQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGK 3000
Query: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ
Sbjct: 3001 GLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQ 3060
Query: 3061 MLQVMEN 3067
MLQ ++
Sbjct: 3061 MLQASKS 3067
>gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo
sapiens]
Length = 3710
Score = 1700 bits (4402), Expect = 0.0
Identities = 1005/2610 (38%), Positives = 1544/2610 (59%), Gaps = 150/2610 (5%)
Query: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
Query: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
Query: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
D+QLT + L +R + + I + NLE F+ R
Sbjct: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
Query: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Query: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
Query: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
Query: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561
Query: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621
Query: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681
Query: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741
Query: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801
Query: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860
Query: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915
Query: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975
Query: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035
Query: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095
Query: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155
Query: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215
Query: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273
Query: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325
Query: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384
Query: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444
Query: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504
Query: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564
Query: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623
Query: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682
Query: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741
Query: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801
Query: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861
Query: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921
Query: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980
Query: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039
Query: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097
Query: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153
Query: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213
Query: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273
Query: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331
Query: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391
Query: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451
Query: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511
Query: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571
Query: 3057 TGNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFD 3114
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F+
Sbjct: 3572 EGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFE 3631
Query: 3115 EFTKEPFIVHGRRLRIEAKERVKSVFHARE 3144
+F P V L+I KE + +FH ++
Sbjct: 3632 DFVFPP-SVSENVLKISVKE--QGLFHKKD 3658
Score = 1149 bits (2971), Expect = 0.0
Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
Query: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
Query: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
Query: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Query: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
Query: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
Query: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
Query: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
Query: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
Query: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066
I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + +
Sbjct: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055
Query: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126
++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F
Sbjct: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115
Query: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186
+ Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT
Sbjct: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175
Query: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246
QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++
Sbjct: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235
Query: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306
++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +
Sbjct: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295
Query: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339
VP + L M L+QED+ +F+ L N+
Sbjct: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
Score = 54.7 bits (130), Expect = 1e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
Query: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
Query: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
Query: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
Query: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
Query: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
Query: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
M+++ E+ +P P V V+ ++ S+
Sbjct: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
>gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo
sapiens]
Length = 3753
Score = 1700 bits (4402), Expect = 0.0
Identities = 1005/2610 (38%), Positives = 1544/2610 (59%), Gaps = 150/2610 (5%)
Query: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
Query: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
Query: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
D+QLT + L +R + + I + NLE F+ R
Sbjct: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
Query: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Query: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
Query: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
Query: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1604
Query: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1605 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1664
Query: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1665 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1724
Query: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1725 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1784
Query: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1785 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1844
Query: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1845 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1903
Query: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1904 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1958
Query: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1959 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 2018
Query: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 2019 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2078
Query: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 2079 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2138
Query: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 2139 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2198
Query: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 2199 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2258
Query: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 2259 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2316
Query: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 2317 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2368
Query: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 2369 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2427
Query: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 2428 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2487
Query: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 2488 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2547
Query: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 2548 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2607
Query: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2608 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2666
Query: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2667 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2725
Query: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2726 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2784
Query: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2785 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2844
Query: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2845 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2904
Query: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2905 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2964
Query: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2965 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 3023
Query: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 3024 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3082
Query: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 3083 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3140
Query: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 3141 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3196
Query: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 3197 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3256
Query: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 3257 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3316
Query: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 3317 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3374
Query: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 3375 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3434
Query: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 3435 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3494
Query: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 3495 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3554
Query: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 3555 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3614
Query: 3057 TGNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFD 3114
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F+
Sbjct: 3615 EGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFE 3674
Query: 3115 EFTKEPFIVHGRRLRIEAKERVKSVFHARE 3144
+F P V L+I KE + +FH ++
Sbjct: 3675 DFVFPP-SVSENVLKISVKE--QGLFHKKD 3701
Score = 1131 bits (2926), Expect = 0.0
Identities = 618/1396 (44%), Positives = 889/1396 (63%), Gaps = 82/1396 (5%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
A QK ++ H E K+D
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
Query: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
Query: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
Query: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
Query: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
Query: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
Query: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
Query: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
Query: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
Query: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVS--- 1025
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P S+++S V+
Sbjct: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIP-SDDQSISVAKEV 1056
Query: 1026 --TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSE 1083
+TE + K + K A+ S + DII ++ A+L+ + + ++K NI+EIKI+GLDS
Sbjct: 1057 QISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSS 1115
Query: 1084 MIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN 1143
+ ++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+
Sbjct: 1116 LSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMS 1175
Query: 1144 VVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQR 1203
VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQR
Sbjct: 1176 KVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQR 1235
Query: 1204 SSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIK 1263
S R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++
Sbjct: 1236 SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQ 1295
Query: 1264 LSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFIL 1323
L+++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L
Sbjct: 1296 LTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSL 1355
Query: 1324 SQEDITTIFKTLHGNI 1339
+QED+ +F+ L N+
Sbjct: 1356 NQEDLNLLFRILTENL 1371
Score = 54.7 bits (130), Expect = 1e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
Query: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
Query: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
Query: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
Query: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
Query: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
Query: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
M+++ E+ +P P V V+ ++ S+
Sbjct: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
>gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo
sapiens]
Length = 3585
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
Query: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
Query: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
D+QLT + L +R + + I + NLE F+ R
Sbjct: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
Query: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Query: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
Query: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
Query: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561
Query: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621
Query: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681
Query: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741
Query: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801
Query: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860
Query: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915
Query: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975
Query: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035
Query: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095
Query: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155
Query: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215
Query: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273
Query: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325
Query: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384
Query: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444
Query: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504
Query: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564
Query: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623
Query: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682
Query: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741
Query: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801
Query: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861
Query: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921
Query: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980
Query: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039
Query: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097
Query: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153
Query: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213
Query: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273
Query: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331
Query: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391
Query: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451
Query: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511
Query: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571
Query: 3057 TGNQMLQ 3063
G+ +L+
Sbjct: 3572 EGSDLLE 3578
Score = 1149 bits (2971), Expect = 0.0
Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
Query: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
Query: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
Query: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
Query: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
Query: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
Query: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
Query: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
Query: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
Query: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Query: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
Query: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
Query: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
Query: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
Query: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
Query: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066
I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + +
Sbjct: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055
Query: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126
++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F
Sbjct: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115
Query: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186
+ Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT
Sbjct: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175
Query: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246
QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++
Sbjct: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235
Query: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306
++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +
Sbjct: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295
Query: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339
VP + L M L+QED+ +F+ L N+
Sbjct: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
Score = 54.7 bits (130), Expect = 1e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
Query: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
Query: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
Query: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
Query: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
Query: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
Query: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
M+++ E+ +P P V V+ ++ S+
Sbjct: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
>gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo
sapiens]
Length = 3628
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
Query: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
Query: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
D+QLT + L +R + + I + NLE F+ R
Sbjct: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
Query: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Query: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
Query: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
Query: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1604
Query: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1605 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1664
Query: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1665 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1724
Query: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1725 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1784
Query: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1785 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1844
Query: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1845 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1903
Query: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1904 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1958
Query: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1959 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 2018
Query: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 2019 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2078
Query: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 2079 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2138
Query: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 2139 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2198
Query: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 2199 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2258
Query: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 2259 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2316
Query: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 2317 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2368
Query: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 2369 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2427
Query: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 2428 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2487
Query: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 2488 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2547
Query: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 2548 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2607
Query: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2608 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2666
Query: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2667 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2725
Query: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2726 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2784
Query: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2785 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2844
Query: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2845 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2904
Query: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2905 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2964
Query: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2965 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 3023
Query: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 3024 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3082
Query: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 3083 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3140
Query: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 3141 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3196
Query: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 3197 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3256
Query: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 3257 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3316
Query: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 3317 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3374
Query: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 3375 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3434
Query: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 3435 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3494
Query: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 3495 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3554
Query: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 3555 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3614
Query: 3057 TGNQMLQ 3063
G+ +L+
Sbjct: 3615 EGSDLLE 3621
Score = 1131 bits (2926), Expect = 0.0
Identities = 618/1396 (44%), Positives = 889/1396 (63%), Gaps = 82/1396 (5%)
Query: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
A QK ++ H E K+D
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
Query: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
Query: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
Query: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
Query: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
Query: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
Query: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
Query: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
Query: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
Query: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVS--- 1025
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P S+++S V+
Sbjct: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIP-SDDQSISVAKEV 1056
Query: 1026 --TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSE 1083
+TE + K + K A+ S + DII ++ A+L+ + + ++K NI+EIKI+GLDS
Sbjct: 1057 QISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSS 1115
Query: 1084 MIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN 1143
+ ++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+
Sbjct: 1116 LSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMS 1175
Query: 1144 VVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQR 1203
VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQR
Sbjct: 1176 KVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQR 1235
Query: 1204 SSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIK 1263
S R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++
Sbjct: 1236 SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQ 1295
Query: 1264 LSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFIL 1323
L+++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L
Sbjct: 1296 LTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSL 1355
Query: 1324 SQEDITTIFKTLHGNI 1339
+QED+ +F+ L N+
Sbjct: 1356 NQEDLNLLFRILTENL 1371
Score = 54.7 bits (130), Expect = 1e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
Query: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
Query: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
Query: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
Query: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
Query: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
Query: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
M+++ E+ +P P V V+ ++ S+
Sbjct: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 212 bits (540), Expect = 4e-54
Identities = 205/933 (21%), Positives = 401/933 (42%), Gaps = 160/933 (17%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
+ E +V VLN +LG YV +L+T QLS+ + KGAV L+NL +K++AL +L++PF+VK G
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEA 121
IG + L IP+ + P + ++L+ P ++ KE+ E K+ L+ +EE
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 122 KQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQN 181
+ D++Q + +VT+I++N+++KI +H+R+ED +TN P +FGI ++N
Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178
Query: 182 LSMQTTDQYWVPCLHDETEKLVR-KLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
+SMQ +++ +KL+R K + + YW+V + L D +L+ +
Sbjct: 179 VSMQN-------AVNEPVQKLMRKKQLDVAEFSIYWDVDCTL--LGDLPQM--ELQEAMA 227
Query: 241 NENIVPEGYDFVFRPISANAKLVMN--RRSDFDFSAPKINLEIELHNIAIEFNKPQYFSI 298
++ + +V P+ A+A L N ++ +P+I+ +I+L I ++ ++ QY I
Sbjct: 228 -RSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQI 286
Query: 299 MELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKH 358
ME L+ ++ + + +R++KP V + + REWW +A++ L + + +W +
Sbjct: 287 MEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFMLHR 345
Query: 359 RQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYK 418
+ Y + Y KL + + +E+ + I R+ K +
Sbjct: 346 ARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHK--QEELA 403
Query: 419 EGVKDPE-DNKG--------------------WFSWLWSWSEQNTNEQQPDVQPETLEEM 457
E +++P+ D+ G WF W Q T E +E +
Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE------GNVVEGL 457
Query: 458 LTPEEKALLYEAIGYSETAVDPT----LLKTFEA-----LKFFVHLKSMSIVLRENHQ-K 507
+++ + E I +E DPT + T+ K + L+ ++ L Q
Sbjct: 458 SAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGT 517
Query: 508 PEL------------VDIVIEEF----STLIVQRPGAQAIK-FETKIDSFHITGLPDNSE 550
P++ V ++ E S+L+ R G ++ T+ F + P+ +
Sbjct: 518 PQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQK 577
Query: 551 KPRLLS-----------------SLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIY 593
+ +S + D +F++ +E NP +R + PL IIY
Sbjct: 578 EVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIY 637
Query: 594 DARTVNSIVEFFRPPK------------EVHLAQLTAATLTKLE-----EFRSKTATGLL 636
+ + + + +FF K E+ +A+ KL+ E R +T LL
Sbjct: 638 NPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIR-QTLDRLL 696
Query: 637 Y--IIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQG 694
IE K +++++ A +I P D F L+++DLG + +T+ + + G
Sbjct: 697 VGDFIEESKRWTVRLDISAPQVIFPDDFKFK-NPVLVVVDLGRMLLTNTQDNSRRKSRDG 755
Query: 695 EANLKE-----------------------------------------------IMDRAYD 707
A+ + + + Y+
Sbjct: 756 SASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYE 815
Query: 708 SFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVF-MDVRMPKFKI 766
+ + +Q++ RV DNW+ + + V H++ + +L+L + +++ D + P +
Sbjct: 816 RYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVL 875
Query: 767 YGKLPLISLRISDKKLQGIMELIESIPKPEPVT 799
G LP + + I++ K+ + + PE T
Sbjct: 876 SGNLPDLKIHINEDKISALKNCFALLTTPEMKT 908
Score = 128 bits (322), Expect = 8e-29
Identities = 114/483 (23%), Positives = 212/483 (43%), Gaps = 51/483 (10%)
Query: 2627 LPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDV 2686
L + V Y A + I +Q+ NQ+ G PF+ Y V P + P V
Sbjct: 3829 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3887
Query: 2687 SIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIE 2746
+ V + + + K+ + Q ++++ + L + +EVE + +++
Sbjct: 3888 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQA--ESEVEKYDENLH 3945
Query: 2747 AFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNL 2806
KTA +Q + YF +L +S+ + K S +P+ L
Sbjct: 3946 E-----KTA---EQGGTPIRYYFE------NLKISIP----QIKLSVFTSNKLPL-DLKA 3986
Query: 2807 LLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVL 2866
L ++G L +D V L F + + T + +++++H+ ++ + Q ++ +D L
Sbjct: 3987 LKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4046
Query: 2867 GNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITG 2926
GNP GL+ + SEGV G + G L+ G++ +A+K G
Sbjct: 4047 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4089
Query: 2927 AMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGA 2986
++ G+ TMD +Q +R E + A E + G GL G + G+T ++T ++G
Sbjct: 4090 TLSDGLGK-TMDNRHQSER-EYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4147
Query: 2987 Q-KGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETS----EVESLRPPR- 3040
+ +GG +GF G+GKGLVG V +P G +D AS T Q ++ S + + +R PR
Sbjct: 4148 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4207
Query: 3041 FFNEDGVIRPYRLRDGTG-NQMLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTK 3099
G++ Y G Q+ ++ +N + ++F V + ++I+ + V F+
Sbjct: 4208 CTGPQGLLPRYSESQAEGQEQLFKLTDN---IQDEFFIAVENIDSYCVLISSKAVYFLKS 4264
Query: 3100 GTF 3102
G +
Sbjct: 4265 GDY 4267
Score = 75.1 bits (183), Expect = 1e-12
Identities = 74/311 (23%), Positives = 142/311 (45%), Gaps = 60/311 (19%)
Query: 959 EDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINY--------- 1009
+ L+ + +K P+ S+YN V + I V+F+ LD+ + + + +++
Sbjct: 1782 DSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADN 1841
Query: 1010 ----------LHNILPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELS 1059
LHN+ K P ++ E+ + V KL LK+ + ++ + +EL+
Sbjct: 1842 HAMRLPPEGILHNV------KLEPHASMESGLQDPVNTKLDLKVHSLSLVLN-KTTSELA 1894
Query: 1060 CLQIFIQDQKCNISEI--KIEGLDSEMIMRPSETEINAKLRNIIVLDSDITA---IYKKA 1114
K N+S++ +E ++ ++ ++ S ++ SD+T Y++
Sbjct: 1895 ---------KANVSKLVAHLEMIEGDLALQGSIGSLSL---------SDLTCHGEFYRER 1936
Query: 1115 VYITGKEVFSFKMVSY--MDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFI 1172
+G+E F+ Y D + DI+V+L + ++ V +F ++AFI
Sbjct: 1937 FTTSGEEALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFI 1990
Query: 1173 DNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVA 1232
+F + L Q A + V++ AQR SR+ LDI APV++IP+S S N+ VA
Sbjct: 1991 QHFTQLQDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVA 2047
Query: 1233 DFGLITMTNTF 1243
+ G + + N F
Sbjct: 2048 NLGKLKVKNKF 2058
Score = 71.6 bits (174), Expect = 1e-11
Identities = 111/531 (20%), Positives = 223/531 (41%), Gaps = 72/531 (13%)
Query: 1983 TVEGS--KKVTIRSPVQIRNHFSVPL-------SVYEGDTLLGTASPENEFNIPLGSYRS 2033
T+EGS K +T+RS + +RN P+ S + +L P + F +PL
Sbjct: 3012 TMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSW 3071
Query: 2034 FIFLKPEDENYQMCEG-IDFEEIIKN-DGALLKKKCRSKNPSKESFL-INIVPEKDNLTS 2090
+ +P+ C+ I + ++K + + K++C S + K F + +K+N
Sbjct: 3072 RLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPD 3131
Query: 2091 L---SVYSEDGWDL----PYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQI 2143
+++S+ + + ++L P +++ NLLP ++ +Y++G+ + TL G A +
Sbjct: 3132 YMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPING-TLKPGKEAAL 3190
Query: 2144 CTAQLGKARLHLKL-LDYLNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTY 2202
TA + +++L + N E I P Q+ ++ + ++ + L++ + +
Sbjct: 3191 HTADTSQ---NIELGVSLENFPLCKELLIPPGTQN--YMVRMRLYDVNRRQLNLTIRIVC 3245
Query: 2203 NT-GQTVVAFHSPYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLF-SFQPNHFFNNNKVQ 2260
G + +PYW++NKTG L ++ D +++ L S P F +K Q
Sbjct: 3246 RAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQ 3305
Query: 2261 LMVTDSELS------------NQFSIDTVGSHGAVKCKGLK------MDYQVGVTI--DL 2300
+ + FS+D G G K ++ + Y +G+ +
Sbjct: 3306 PNLCTMRIGRGIHPEGMPGWCQGFSLD--GGSGVRALKVIQQGNRPGLIYNIGIDVKKGR 3363
Query: 2301 SSFNITRIVTFTPFYMIKNKSKYHISVAEE---------GNDKWLS-LDLEQCIPFWPEY 2350
+ T +V F P Y++ NKS + ++ A+ + ++S L + WP
Sbjct: 3364 GRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRN 3423
Query: 2351 ASSKLLIQVERSEDPPKRIYFN----KQENCILLRLDNELGG---IIAEVNLAEHSTVIT 2403
+LL R D P I+ + N + + + LG + E+ L + I+
Sbjct: 3424 DYDQLL--CVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRIS 3481
Query: 2404 FLDYHDGAATFLLINHTKNELVQYNQSSLSE--IEDSLPPGKAVFYTWADP 2452
F D F + N +K +V + Q ++E + + P ++ Y W +P
Sbjct: 3482 FSDTDQLPPPFRIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEP 3531
Score = 47.0 bits (110), Expect = 3e-04
Identities = 76/386 (19%), Positives = 143/386 (37%), Gaps = 70/386 (18%)
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D + V L L E L+ LEY P + ++ LQ+I + ++LDI L+ E
Sbjct: 1060 DRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTLQVISLQVNNLDIILNPE 1117
Query: 1002 ALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCL 1061
++ I +L P+ ++ +P ++ ++ ST E ++ E+ L
Sbjct: 1118 TIVELIGFLQKSFPKEKDDLSPQPLMTDFERS--FREQGTYQSTYEQ--NTEVAVEIHRL 1173
Query: 1062 QIFI---------QDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYK 1112
+ + + I+ I G + M S ++N L + ++D +
Sbjct: 1174 NLLLLRTVGMANREKYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKN 1232
Query: 1113 KAVYITGKEV-----------FSFKMVSYMDATAGSA----YTDMNVVDIQVNLIVGCIE 1157
+ V G V F V DA A + + + + +NL + +
Sbjct: 1233 QYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLH 1292
Query: 1158 VVFVTKFLYSILAFIDNFQAA-KQALAEATVQAAGMAATGVKELAQRSS----------- 1205
KFL + +D + + L A + + AT E ++ S
Sbjct: 1293 YNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREP 1352
Query: 1206 ---------------------RMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFH 1244
++ L+INI++PVV IP+ P S + V G I + N
Sbjct: 1353 FILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVA 1412
Query: 1245 MITESQSSPPPVIDLITIKLSEMRLY 1270
ES+S D + +++ +++LY
Sbjct: 1413 GDDESRS------DRLQVEIKDIKLY 1432
Score = 39.7 bits (91), Expect = 0.048
Identities = 30/138 (21%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
Query: 972 NVPDLKSTYN-NVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETE 1030
N+PDLK N + + +K F+ L E + I PQ E++ + +
Sbjct: 878 NLPDLKIHINEDKISALKNCFALLTT---PEMKTSDTQIKEKIFPQEEQRGSLQDSVMNL 934
Query: 1031 DKGDVIKKLALKLSTNEDIITLQILA---ELSCLQIFIQDQKCNISEIKIEGLDSEMIMR 1087
+ V+ L+ T E ++ Q+L +++C+Q+ ++ IS +K+ G ++ + R
Sbjct: 935 TQSIVL----LEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR 990
Query: 1088 PSETEINAKLRNIIVLDS 1105
P + E++ + ++++D+
Sbjct: 991 PYDAEVSLTVHGLLLVDT 1008
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 212 bits (540), Expect = 4e-54
Identities = 205/933 (21%), Positives = 401/933 (42%), Gaps = 160/933 (17%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
+ E +V VLN +LG YV +L+T QLS+ + KGAV L+NL +K++AL +L++PF+VK G
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEA 121
IG + L IP+ + P + ++L+ P ++ KE+ E K+ L+ +EE
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 122 KQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQN 181
+ D++Q + +VT+I++N+++KI +H+R+ED +TN P +FGI ++N
Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178
Query: 182 LSMQTTDQYWVPCLHDETEKLVR-KLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
+SMQ +++ +KL+R K + + YW+V + L D +L+ +
Sbjct: 179 VSMQN-------AVNEPVQKLMRKKQLDVAEFSIYWDVDCTL--LGDLPQM--ELQEAMA 227
Query: 241 NENIVPEGYDFVFRPISANAKLVMN--RRSDFDFSAPKINLEIELHNIAIEFNKPQYFSI 298
++ + +V P+ A+A L N ++ +P+I+ +I+L I ++ ++ QY I
Sbjct: 228 -RSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQI 286
Query: 299 MELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKH 358
ME L+ ++ + + +R++KP V + + REWW +A++ L + + +W +
Sbjct: 287 MEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFMLHR 345
Query: 359 RQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYK 418
+ Y + Y KL + + +E+ + I R+ K +
Sbjct: 346 ARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHK--QEELA 403
Query: 419 EGVKDPE-DNKG--------------------WFSWLWSWSEQNTNEQQPDVQPETLEEM 457
E +++P+ D+ G WF W Q T E +E +
Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE------GNVVEGL 457
Query: 458 LTPEEKALLYEAIGYSETAVDPT----LLKTFEA-----LKFFVHLKSMSIVLRENHQ-K 507
+++ + E I +E DPT + T+ K + L+ ++ L Q
Sbjct: 458 SAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGT 517
Query: 508 PEL------------VDIVIEEF----STLIVQRPGAQAIK-FETKIDSFHITGLPDNSE 550
P++ V ++ E S+L+ R G ++ T+ F + P+ +
Sbjct: 518 PQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQK 577
Query: 551 KPRLLS-----------------SLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIY 593
+ +S + D +F++ +E NP +R + PL IIY
Sbjct: 578 EVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIY 637
Query: 594 DARTVNSIVEFFRPPK------------EVHLAQLTAATLTKLE-----EFRSKTATGLL 636
+ + + + +FF K E+ +A+ KL+ E R +T LL
Sbjct: 638 NPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIR-QTLDRLL 696
Query: 637 Y--IIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQG 694
IE K +++++ A +I P D F L+++DLG + +T+ + + G
Sbjct: 697 VGDFIEESKRWTVRLDISAPQVIFPDDFKFK-NPVLVVVDLGRMLLTNTQDNSRRKSRDG 755
Query: 695 EANLKE-----------------------------------------------IMDRAYD 707
A+ + + + Y+
Sbjct: 756 SASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYE 815
Query: 708 SFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVF-MDVRMPKFKI 766
+ + +Q++ RV DNW+ + + V H++ + +L+L + +++ D + P +
Sbjct: 816 RYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVL 875
Query: 767 YGKLPLISLRISDKKLQGIMELIESIPKPEPVT 799
G LP + + I++ K+ + + PE T
Sbjct: 876 SGNLPDLKIHINEDKISALKNCFALLTTPEMKT 908
Score = 128 bits (322), Expect = 8e-29
Identities = 114/483 (23%), Positives = 212/483 (43%), Gaps = 51/483 (10%)
Query: 2627 LPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDV 2686
L + V Y A + I +Q+ NQ+ G PF+ Y V P + P V
Sbjct: 3854 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3912
Query: 2687 SIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIE 2746
+ V + + + K+ + Q ++++ + L + +EVE + +++
Sbjct: 3913 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQA--ESEVEKYDENLH 3970
Query: 2747 AFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNL 2806
KTA +Q + YF +L +S+ + K S +P+ L
Sbjct: 3971 E-----KTA---EQGGTPIRYYFE------NLKISIP----QIKLSVFTSNKLPL-DLKA 4011
Query: 2807 LLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVL 2866
L ++G L +D V L F + + T + +++++H+ ++ + Q ++ +D L
Sbjct: 4012 LKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4071
Query: 2867 GNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITG 2926
GNP GL+ + SEGV G + G L+ G++ +A+K G
Sbjct: 4072 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4114
Query: 2927 AMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGA 2986
++ G+ TMD +Q +R E + A E + G GL G + G+T ++T ++G
Sbjct: 4115 TLSDGLGK-TMDNRHQSER-EYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4172
Query: 2987 Q-KGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETS----EVESLRPPR- 3040
+ +GG +GF G+GKGLVG V +P G +D AS T Q ++ S + + +R PR
Sbjct: 4173 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4232
Query: 3041 FFNEDGVIRPYRLRDGTG-NQMLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTK 3099
G++ Y G Q+ ++ +N + ++F V + ++I+ + V F+
Sbjct: 4233 CTGPQGLLPRYSESQAEGQEQLFKLTDN---IQDEFFIAVENIDSYCVLISSKAVYFLKS 4289
Query: 3100 GTF 3102
G +
Sbjct: 4290 GDY 4292
Score = 75.1 bits (183), Expect = 1e-12
Identities = 74/311 (23%), Positives = 142/311 (45%), Gaps = 60/311 (19%)
Query: 959 EDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINY--------- 1009
+ L+ + +K P+ S+YN V + I V+F+ LD+ + + + +++
Sbjct: 1782 DSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADN 1841
Query: 1010 ----------LHNILPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELS 1059
LHN+ K P ++ E+ + V KL LK+ + ++ + +EL+
Sbjct: 1842 HAMRLPPEGILHNV------KLEPHASMESGLQDPVNTKLDLKVHSLSLVLN-KTTSELA 1894
Query: 1060 CLQIFIQDQKCNISEI--KIEGLDSEMIMRPSETEINAKLRNIIVLDSDITA---IYKKA 1114
K N+S++ +E ++ ++ ++ S ++ SD+T Y++
Sbjct: 1895 ---------KANVSKLVAHLEMIEGDLALQGSIGSLSL---------SDLTCHGEFYRER 1936
Query: 1115 VYITGKEVFSFKMVSY--MDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFI 1172
+G+E F+ Y D + DI+V+L + ++ V +F ++AFI
Sbjct: 1937 FTTSGEEALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFI 1990
Query: 1173 DNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVA 1232
+F + L Q A + V++ AQR SR+ LDI APV++IP+S S N+ VA
Sbjct: 1991 QHFTQLQDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVA 2047
Query: 1233 DFGLITMTNTF 1243
+ G + + N F
Sbjct: 2048 NLGKLKVKNKF 2058
Score = 71.6 bits (174), Expect = 1e-11
Identities = 111/531 (20%), Positives = 223/531 (41%), Gaps = 72/531 (13%)
Query: 1983 TVEGS--KKVTIRSPVQIRNHFSVPL-------SVYEGDTLLGTASPENEFNIPLGSYRS 2033
T+EGS K +T+RS + +RN P+ S + +L P + F +PL
Sbjct: 3037 TMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSW 3096
Query: 2034 FIFLKPEDENYQMCEG-IDFEEIIKN-DGALLKKKCRSKNPSKESFL-INIVPEKDNLTS 2090
+ +P+ C+ I + ++K + + K++C S + K F + +K+N
Sbjct: 3097 RLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPD 3156
Query: 2091 L---SVYSEDGWDL----PYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQI 2143
+++S+ + + ++L P +++ NLLP ++ +Y++G+ + TL G A +
Sbjct: 3157 YMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPING-TLKPGKEAAL 3215
Query: 2144 CTAQLGKARLHLKL-LDYLNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTY 2202
TA + +++L + N E I P Q+ ++ + ++ + L++ + +
Sbjct: 3216 HTADTSQ---NIELGVSLENFPLCKELLIPPGTQN--YMVRMRLYDVNRRQLNLTIRIVC 3270
Query: 2203 NT-GQTVVAFHSPYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLF-SFQPNHFFNNNKVQ 2260
G + +PYW++NKTG L ++ D +++ L S P F +K Q
Sbjct: 3271 RAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQ 3330
Query: 2261 LMVTDSELS------------NQFSIDTVGSHGAVKCKGLK------MDYQVGVTI--DL 2300
+ + FS+D G G K ++ + Y +G+ +
Sbjct: 3331 PNLCTMRIGRGIHPEGMPGWCQGFSLD--GGSGVRALKVIQQGNRPGLIYNIGIDVKKGR 3388
Query: 2301 SSFNITRIVTFTPFYMIKNKSKYHISVAEE---------GNDKWLS-LDLEQCIPFWPEY 2350
+ T +V F P Y++ NKS + ++ A+ + ++S L + WP
Sbjct: 3389 GRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRN 3448
Query: 2351 ASSKLLIQVERSEDPPKRIYFN----KQENCILLRLDNELGG---IIAEVNLAEHSTVIT 2403
+LL R D P I+ + N + + + LG + E+ L + I+
Sbjct: 3449 DYDQLL--CVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRIS 3506
Query: 2404 FLDYHDGAATFLLINHTKNELVQYNQSSLSE--IEDSLPPGKAVFYTWADP 2452
F D F + N +K +V + Q ++E + + P ++ Y W +P
Sbjct: 3507 FSDTDQLPPPFRIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEP 3556
Score = 47.0 bits (110), Expect = 3e-04
Identities = 76/386 (19%), Positives = 143/386 (37%), Gaps = 70/386 (18%)
Query: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
D + V L L E L+ LEY P + ++ LQ+I + ++LDI L+ E
Sbjct: 1060 DRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTLQVISLQVNNLDIILNPE 1117
Query: 1002 ALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCL 1061
++ I +L P+ ++ +P ++ ++ ST E ++ E+ L
Sbjct: 1118 TIVELIGFLQKSFPKEKDDLSPQPLMTDFERS--FREQGTYQSTYEQ--NTEVAVEIHRL 1173
Query: 1062 QIFI---------QDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYK 1112
+ + + I+ I G + M S ++N L + ++D +
Sbjct: 1174 NLLLLRTVGMANREKYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKN 1232
Query: 1113 KAVYITGKEV-----------FSFKMVSYMDATAGSA----YTDMNVVDIQVNLIVGCIE 1157
+ V G V F V DA A + + + + +NL + +
Sbjct: 1233 QYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLH 1292
Query: 1158 VVFVTKFLYSILAFIDNFQAA-KQALAEATVQAAGMAATGVKELAQRSS----------- 1205
KFL + +D + + L A + + AT E ++ S
Sbjct: 1293 YNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREP 1352
Query: 1206 ---------------------RMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFH 1244
++ L+INI++PVV IP+ P S + V G I + N
Sbjct: 1353 FILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVA 1412
Query: 1245 MITESQSSPPPVIDLITIKLSEMRLY 1270
ES+S D + +++ +++LY
Sbjct: 1413 GDDESRS------DRLQVEIKDIKLY 1432
Score = 39.7 bits (91), Expect = 0.048
Identities = 30/138 (21%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
Query: 972 NVPDLKSTYN-NVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETE 1030
N+PDLK N + + +K F+ L E + I PQ E++ + +
Sbjct: 878 NLPDLKIHINEDKISALKNCFALLTT---PEMKTSDTQIKEKIFPQEEQRGSLQDSVMNL 934
Query: 1031 DKGDVIKKLALKLSTNEDIITLQILA---ELSCLQIFIQDQKCNISEIKIEGLDSEMIMR 1087
+ V+ L+ T E ++ Q+L +++C+Q+ ++ IS +K+ G ++ + R
Sbjct: 935 TQSIVL----LEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR 990
Query: 1088 PSETEINAKLRNIIVLDS 1105
P + E++ + ++++D+
Sbjct: 991 PYDAEVSLTVHGLLLVDT 1008
>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
Length = 4022
Score = 108 bits (269), Expect = 1e-22
Identities = 70/250 (28%), Positives = 117/250 (46%), Gaps = 18/250 (7%)
Query: 2798 LIPVH-SLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQM 2856
L+ +H SL L + S L+ + FE F T L + HY+ A+ +
Sbjct: 3596 LVSIHASLKLYIASDHTPLS--------FSVFERGPIFTTARQLVHALAMHYAAGALFRA 3647
Query: 2857 YVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGG 2916
++ LD+LG+P L+R GV FF PY+G +GP FV G++ G + V G
Sbjct: 3648 GWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKG 3707
Query: 2917 LAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGIT 2976
+ + + ++A+ + +++DE++ ++ E + P EG+ +G L + I
Sbjct: 3708 TLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIA 3767
Query: 2977 GIVTKPIKGAQKGG---------AAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRA 3027
GIV +P++ QK A G GVGKG++G +P GG ++ S T GI
Sbjct: 3768 GIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHG 3827
Query: 3028 TETSEVESLR 3037
S++ R
Sbjct: 3828 AGLSQLPKQR 3837
Score = 74.3 bits (181), Expect = 2e-12
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 21/219 (9%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQ-LDVPFKVKVG 60
+ ES V +L ++ Y+ +L S L L +W G V L L++K + L Q L +PF G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HI L++ +PW L ++PV + + ++ ++K D ++++ + + E
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECIL----KLK-DGIQDDHESCGSNSTNRSTAES 115
Query: 121 AKQKVVDQ--EQHLPEKQDT---FAEKLVTQIIKNLQVKISSIHIRY-EDDITNRDKPLS 174
K + + +Q P D + + L+ +++ N+ + I+++ ++Y EDDI
Sbjct: 116 TKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV------- 168
Query: 175 FGISLQNLSMQTTDQYWVPCLHD--ETEKLVRKLIRLDN 211
+++ + T + W D T+ ++RK+I +
Sbjct: 169 LSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSD 207
>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
Length = 3997
Score = 108 bits (269), Expect = 1e-22
Identities = 70/250 (28%), Positives = 117/250 (46%), Gaps = 18/250 (7%)
Query: 2798 LIPVH-SLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQM 2856
L+ +H SL L + S L+ + FE F T L + HY+ A+ +
Sbjct: 3571 LVSIHASLKLYIASDHTPLS--------FSVFERGPIFTTARQLVHALAMHYAAGALFRA 3622
Query: 2857 YVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGG 2916
++ LD+LG+P L+R GV FF PY+G +GP FV G++ G + V G
Sbjct: 3623 GWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKG 3682
Query: 2917 LAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGIT 2976
+ + + ++A+ + +++DE++ ++ E + P EG+ +G L + I
Sbjct: 3683 TLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIA 3742
Query: 2977 GIVTKPIKGAQKGG---------AAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRA 3027
GIV +P++ QK A G GVGKG++G +P GG ++ S T GI
Sbjct: 3743 GIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHG 3802
Query: 3028 TETSEVESLR 3037
S++ R
Sbjct: 3803 AGLSQLPKQR 3812
Score = 74.3 bits (181), Expect = 2e-12
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 21/219 (9%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQ-LDVPFKVKVG 60
+ ES V +L ++ Y+ +L S L L +W G V L L++K + L Q L +PF G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HI L++ +PW L ++PV + + ++ ++K D ++++ + + E
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECIL----KLK-DGIQDDHESCGSNSTNRSTAES 115
Query: 121 AKQKVVDQ--EQHLPEKQDT---FAEKLVTQIIKNLQVKISSIHIRY-EDDITNRDKPLS 174
K + + +Q P D + + L+ +++ N+ + I+++ ++Y EDDI
Sbjct: 116 TKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV------- 168
Query: 175 FGISLQNLSMQTTDQYWVPCLHD--ETEKLVRKLIRLDN 211
+++ + T + W D T+ ++RK+I +
Sbjct: 169 LSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSD 207
>gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens]
Length = 415
Score = 74.3 bits (181), Expect = 2e-12
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 21/219 (9%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQ-LDVPFKVKVG 60
+ ES V +L ++ Y+ +L S L L +W G V L L++K + L Q L +PF G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HI L++ +PW L ++PV + + ++ ++K D ++++ + + E
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECIL----KLK-DGIQDDHESCGSNSTNRSTAES 115
Query: 121 AKQKVVDQ--EQHLPEKQDT---FAEKLVTQIIKNLQVKISSIHIRY-EDDITNRDKPLS 174
K + + +Q P D + + L+ +++ N+ + I+++ ++Y EDDI
Sbjct: 116 TKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV------- 168
Query: 175 FGISLQNLSMQTTDQYWVPCLHD--ETEKLVRKLIRLDN 211
+++ + T + W D T+ ++RK+I +
Sbjct: 169 LSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSD 207
>gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]
Length = 863
Score = 74.3 bits (181), Expect = 2e-12
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 21/219 (9%)
Query: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQ-LDVPFKVKVG 60
+ ES V +L ++ Y+ +L S L L +W G V L L++K + L Q L +PF G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
HI L++ +PW L ++PV + + ++ ++K D ++++ + + E
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECIL----KLK-DGIQDDHESCGSNSTNRSTAES 115
Query: 121 AKQKVVDQ--EQHLPEKQDT---FAEKLVTQIIKNLQVKISSIHIRY-EDDITNRDKPLS 174
K + + +Q P D + + L+ +++ N+ + I+++ ++Y EDDI
Sbjct: 116 TKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV------- 168
Query: 175 FGISLQNLSMQTTDQYWVPCLHD--ETEKLVRKLIRLDN 211
+++ + T + W D T+ ++RK+I +
Sbjct: 169 LSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSD 207
>gi|239047271 autophagy related 2A [Homo sapiens]
Length = 1938
Score = 47.4 bits (111), Expect = 2e-04
Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 10/189 (5%)
Query: 2 VFESVVVDVLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIK----ENALSQLDVPFK 56
V E V +L+ +LG + + L QLSL ++KG+VAL+++ ++ L ++ P +
Sbjct: 12 VKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLE 71
Query: 57 VKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELK 116
+ G +G++++ +PW L T + + L + P R + + L+
Sbjct: 72 LVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP-RRGPAPGAADSQSWASCMTTSLQ 130
Query: 117 RIEEAKQKVVDQEQHLP---EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPL 173
+E + + + P E + FA+ + T +++ ++V +R E + ++ +
Sbjct: 131 LAQECLRDGLPEPSEPPQPLEGLEMFAQTIET-VLRRIKVTFLDTVVRVEHSPGDGERGV 189
Query: 174 SFGISLQNL 182
+ + +Q L
Sbjct: 190 AVEVRVQRL 198
Score = 35.4 bits (80), Expect = 0.90
Identities = 29/137 (21%), Positives = 50/137 (36%)
Query: 2889 QGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREA 2948
+G +G F A L V + A + ++ +D + RR
Sbjct: 1780 RGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLR 1839
Query: 2949 MNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVAR 3008
+QPA REG+ + + G + I +G ++ G G GV + L V +
Sbjct: 1840 RGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVK 1899
Query: 3009 PTGGIIDMASSTFQGIK 3025
P + SS G++
Sbjct: 1900 PLILATEATSSLLGGMR 1916
>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
Length = 2078
Score = 43.1 bits (100), Expect = 0.004
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 17/220 (7%)
Query: 10 VLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIKENALSQL----DVPFKVKVGHIGN 64
+L R+LG ++ + L QLSL +++G +L + + + L+++ D P +V G I +
Sbjct: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
Query: 65 LKLIIPWKNLYTQPVEAVLEEIYLLIVPSSR--IKYDPLKEEKQLMEAKQQELKRIEEAK 122
+ L +PW +L + + ++ P R +P+ M + Q K E
Sbjct: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPM-YWSSFMTSSMQLAK--ECLS 133
Query: 123 QKVVDQ--EQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISL 179
QK+ D+ E P E + FAE + T +++ ++V +R E N + I +
Sbjct: 134 QKLTDEQGEGSQPFEGLEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIRI 192
Query: 180 QNLSM--QTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWN 217
+ +T D+ +H T KL++L + +W+
Sbjct: 193 ERTVYCDETADESSGINVHQPT-AFAHKLLQLSGVSLFWD 231
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 41.6 bits (96), Expect = 0.013
Identities = 53/256 (20%), Positives = 105/256 (41%), Gaps = 27/256 (10%)
Query: 33 KGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVP 92
K + + ++ EN L Q + P K H+ + K+ +P A +E+I +L
Sbjct: 784 KSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQEN 843
Query: 93 SSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVV--DQEQHLPEKQDTFAEKLVTQIIKN 150
+ ++ L E +L K+++ E +++V QE L EK++ K V QI N
Sbjct: 844 NEGLRAFLLTIENELKNEKEEKA----ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSN 899
Query: 151 LQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQY-WVPCLHDETEKLVRKLIRL 209
+ I+ +H++ + +K + ++ + T+ + +H + + +L L
Sbjct: 900 YDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK----IDELRTL 955
Query: 210 DNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD 269
D++ N+ +L DL NG +N+ D + N LV + +
Sbjct: 956 DSVSQISNIDLL---------NLRDLSNGSEEDNLPNTQLDLL-----GNDYLVSKQVKE 1001
Query: 270 FDFSAPKINLEIELHN 285
+ P N E H+
Sbjct: 1002 YRIQEP--NRENSFHS 1015
Score = 35.0 bits (79), Expect = 1.2
Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Query: 42 QIKENALSQLDVPFKVKVGHI-------GNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSS 94
Q+KE L + +V V++ H+ L + + +E +LE + S+
Sbjct: 1083 QLKEE-LQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSA 1141
Query: 95 RIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVK 154
+++ D L++E +++ ++ LK +E Q V + L K+ E+ +TQ+ NLQ
Sbjct: 1142 KLEQDILEKESIILKL-ERNLKEFQEHLQDSVKNTKDLNVKELKLKEE-ITQLTNNLQDM 1199
Query: 155 ISSIHIRYEDDITNRDK 171
+ ++ E++ TNR +
Sbjct: 1200 KHLLQLKEEEEETNRQE 1216
>gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Homo
sapiens]
Length = 522
Score = 37.0 bits (84), Expect = 0.31
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 13 RFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENAL-SQLDVPFKVKVGHI--GNLKLII 69
+ L + +L +++L KG LKNL++ E L + LD+P + + + + I
Sbjct: 11 KHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRI 70
Query: 70 PWKNLYTQPVEAVLEEIYL 88
PW L T P+ L+++ +
Sbjct: 71 PWTKLKTHPICLSLDKVIM 89
>gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Homo
sapiens]
Length = 1464
Score = 37.0 bits (84), Expect = 0.31
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 13 RFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENAL-SQLDVPFKVKVGHI--GNLKLII 69
+ L + +L +++L KG LKNL++ E L + LD+P + + + + I
Sbjct: 11 KHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRI 70
Query: 70 PWKNLYTQPVEAVLEEIYL 88
PW L T P+ L+++ +
Sbjct: 71 PWTKLKTHPICLSLDKVIM 89
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 35.4 bits (80), Expect = 0.90
Identities = 39/152 (25%), Positives = 49/152 (32%), Gaps = 29/152 (19%)
Query: 2871 GLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAK 2930
G S G++ P QG GP ++ GL LVGGA G ++ TGA
Sbjct: 12 GHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGA 71
Query: 2931 GVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGG 2990
G A G G GG G ++G + G GG
Sbjct: 72 G----------------AYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGG 115
Query: 2991 AAGFFKGVG-------------KGLVGAVARP 3009
G G G + L GAVA P
Sbjct: 116 GGGSSGGAGALSAAGVIRVPAHRPLAGAVAHP 147
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 34.7 bits (78), Expect = 1.5
Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 2523 EIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLEREFK 2582
E AV L + ++ + ++ G T S ++ E P + + + + T+K +++
Sbjct: 2450 EGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVI 2509
Query: 2583 EYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQSS 2642
V++ +N PV + P VI + N L A+ +N AHQ +
Sbjct: 2510 ----------MVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGA 2559
Query: 2643 FRIQIYRIQIQ 2653
+ Q Y++ ++
Sbjct: 2560 VQDQPYQLPVE 2570
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 34.3 bits (77), Expect = 2.0
Identities = 69/362 (19%), Positives = 141/362 (38%), Gaps = 41/362 (11%)
Query: 1513 FLQTVANVFLEAYTTGTAVETSVQT------WTAKEEVPTQESVKWEINVIIKNPEIVFV 1566
FLQT+ +V E YT E + + + ++ E P + ++E+ +N + +
Sbjct: 1202 FLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTL-L 1260
Query: 1567 ADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPC 1626
+T+ LV+ T+ + + + ++L FL + + T L+
Sbjct: 1261 NKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQ---MTNLEDI 1317
Query: 1627 DLFYQT----------TQKGTDPQVIDMSVKSLTLKVSPVIINTMITI----TSALYTTK 1672
D+ +++ T+ Q ++ + SL ++ N I ++
Sbjct: 1318 DVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSE 1377
Query: 1673 ETIPEETASSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGE--MIKMNIDSIF 1730
T+P + + E +T+ + N I + E K E ++K+
Sbjct: 1378 STVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQ 1437
Query: 1731 IVLEAGIGHRTVPMLLA------KSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEP 1784
LE + V M +A SR SG +N +S H + E HY+NEM +
Sbjct: 1438 EQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 1785 L----LEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQ 1840
+ E +++ E+F+P + + K ++ + SDP + +PE K + S++
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKELGEHGK-EILLSNSDPHD----IPESKDCVLTISEEM 1552
Query: 1841 LN 1842
+
Sbjct: 1553 FS 1554
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 34.3 bits (77), Expect = 2.0
Identities = 69/362 (19%), Positives = 141/362 (38%), Gaps = 41/362 (11%)
Query: 1513 FLQTVANVFLEAYTTGTAVETSVQT------WTAKEEVPTQESVKWEINVIIKNPEIVFV 1566
FLQT+ +V E YT E + + + ++ E P + ++E+ +N + +
Sbjct: 1202 FLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTL-L 1260
Query: 1567 ADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPC 1626
+T+ LV+ T+ + + + ++L FL + + T L+
Sbjct: 1261 NKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQ---MTNLEDI 1317
Query: 1627 DLFYQT----------TQKGTDPQVIDMSVKSLTLKVSPVIINTMITI----TSALYTTK 1672
D+ +++ T+ Q ++ + SL ++ N I ++
Sbjct: 1318 DVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSE 1377
Query: 1673 ETIPEETASSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGE--MIKMNIDSIF 1730
T+P + + E +T+ + N I + E K E ++K+
Sbjct: 1378 STVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQ 1437
Query: 1731 IVLEAGIGHRTVPMLLA------KSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEP 1784
LE + V M +A SR SG +N +S H + E HY+NEM +
Sbjct: 1438 EQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 1785 L----LEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQ 1840
+ E +++ E+F+P + + K ++ + SDP + +PE K + S++
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKELGEHGK-EILLSNSDPHD----IPESKDCVLTISEEM 1552
Query: 1841 LN 1842
+
Sbjct: 1553 FS 1554
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 34.3 bits (77), Expect = 2.0
Identities = 84/400 (21%), Positives = 152/400 (38%), Gaps = 85/400 (21%)
Query: 733 LSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESI 792
L V + VP ++E+S V +DV+ P+ K+ G L +++K + +
Sbjct: 3420 LKVPKAEVTVP---DVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMP 3476
Query: 793 PKPEPVTEVSAPVKSFQ---------IQTSTSLGTSQISQKIIPL-LELPSVSEDDSEEE 842
P VSAP +S + ++ SL + Q K L ++ PS D E +
Sbjct: 3477 KFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSA---DLEVQ 3533
Query: 843 FFDAPCSPLEEPLQFPTGVK---------SIRTRKLQKQ--------------------- 872
LE P+ G+K S++T K+ +
Sbjct: 3534 AVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVR 3593
Query: 873 --DCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFL 930
D V++ + ++ + PK ++ L GD L A+ ++ D K
Sbjct: 3594 VPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSL-----------ADKDVTAKDSK----- 3637
Query: 931 KEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVP------DLKSTYNNVL 984
K P++ K P + V+ +ME + + K E +V DLK+T ++
Sbjct: 3638 ----FKMPKF----KMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQ 3689
Query: 985 QL---IKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIK--KL 1039
+KV +D+ L E + L LP+ E S + + + IK KL
Sbjct: 3690 PPSADLKVQAGQMDVKL-PEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKL 3748
Query: 1040 ALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEG 1079
LK+S E + + L +++ +Q + + ++EG
Sbjct: 3749 DLKVSKAE-VTAPDVEVSLPSVEVDVQAPRAKLDSAQLEG 3787
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 33.9 bits (76), Expect = 2.6
Identities = 37/161 (22%), Positives = 75/161 (46%), Gaps = 22/161 (13%)
Query: 72 KNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQH 131
K LY+Q E + EE + E++ L+E LK IEEA +K+ E
Sbjct: 243 KKLYSQYEEKLQEE-----------QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEIS 291
Query: 132 LPEKQDTFAE--KLVTQIIK---NLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQT 186
L EK E +L+ ++ K LQ+++ ++T+ DK + + S++
Sbjct: 292 LEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRE 351
Query: 187 TDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSD 227
++ +H + +K V++++ +N ++S++ YL++
Sbjct: 352 RIRHLDDMVHCQ-QKKVKQMVEENN-----ELQSRLDYLTE 386
>gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens]
Length = 448
Score = 33.9 bits (76), Expect = 2.6
Identities = 26/101 (25%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 48 LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQL 107
+ QL+ F+ + H+ L++ K+L Q +A L+E + L+ +R K K+ + +
Sbjct: 310 VEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQA-LQEHWALMEELNRSK----KDFEAI 364
Query: 108 MEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQII 148
++AK +EL++ +E K+K+ Q++ + + E + II
Sbjct: 365 IQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCII 405
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 33.9 bits (76), Expect = 2.6
Identities = 26/101 (25%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query: 48 LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQL 107
+ QL+ F+ + H+ L++ K+L Q +A L+E + L+ +R K K+ + +
Sbjct: 310 VEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQA-LQEHWALMEELNRSK----KDFEAI 364
Query: 108 MEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQII 148
++AK +EL++ +E K+K+ Q++ + + E + II
Sbjct: 365 IQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCII 405
>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 33.5 bits (75), Expect = 3.4
Identities = 74/310 (23%), Positives = 120/310 (38%), Gaps = 44/310 (14%)
Query: 845 DAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELS 904
DAP P E L T ++ RK+ D + TT + + + + L S
Sbjct: 20 DAPELPEERELM--TNCSNMSLRKVPA-DLTPATTTLDLSYNL------LFQLQSSDFHS 70
Query: 905 VVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTT--------LDN 956
V ++ VL L I+ DLK F KE YLD + + VT LD
Sbjct: 71 VSKLRVLIL-CHNRIQQLDLKTFEFNKEL-----RYLDLSNNRLKSVTWYLLAGLRYLDL 124
Query: 957 TMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQ 1016
+ D T+ + N+ L+ + ++ K +F + HLH LNT+ LP
Sbjct: 125 SFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKI-AHLH----LNTVFLGFRTLPH 179
Query: 1017 SEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIK 1076
EE S P+ T + L + TN ++ + L++ D K S+
Sbjct: 180 YEEGSLPILNTTK-------LHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGK---SQFV 229
Query: 1077 IEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAG 1136
+ + + ++T + L N + L D + + V+ T E F + V++ G
Sbjct: 230 SYEMQRNLSLENAKTSV--LLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTF----GG 283
Query: 1137 SAYTDMNVVD 1146
AY D N D
Sbjct: 284 KAYLDHNSFD 293
>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 33.5 bits (75), Expect = 3.4
Identities = 74/310 (23%), Positives = 120/310 (38%), Gaps = 44/310 (14%)
Query: 845 DAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELS 904
DAP P E L T ++ RK+ D + TT + + + + L S
Sbjct: 20 DAPELPEERELM--TNCSNMSLRKVPA-DLTPATTTLDLSYNL------LFQLQSSDFHS 70
Query: 905 VVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTT--------LDN 956
V ++ VL L I+ DLK F KE YLD + + VT LD
Sbjct: 71 VSKLRVLIL-CHNRIQQLDLKTFEFNKEL-----RYLDLSNNRLKSVTWYLLAGLRYLDL 124
Query: 957 TMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQ 1016
+ D T+ + N+ L+ + ++ K +F + HLH LNT+ LP
Sbjct: 125 SFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKI-AHLH----LNTVFLGFRTLPH 179
Query: 1017 SEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIK 1076
EE S P+ T + L + TN ++ + L++ D K S+
Sbjct: 180 YEEGSLPILNTTK-------LHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGK---SQFV 229
Query: 1077 IEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAG 1136
+ + + ++T + L N + L D + + V+ T E F + V++ G
Sbjct: 230 SYEMQRNLSLENAKTSV--LLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTF----GG 283
Query: 1137 SAYTDMNVVD 1146
AY D N D
Sbjct: 284 KAYLDHNSFD 293
>gi|71773110 apolipoprotein A-IV precursor [Homo sapiens]
Length = 396
Score = 33.1 bits (74), Expect = 4.5
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 13/113 (11%)
Query: 37 ALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRI 96
A+++LQ K QL+ F+ K+G + N Y ++ L +
Sbjct: 45 AVEHLQ-KSELTQQLNALFQDKLGEV----------NTYAGDLQKKLVPFATELHERLAK 93
Query: 97 KYDPLKEE--KQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQI 147
+ LKEE K+L E + + L E QK+ D + L ++ + +A++L TQ+
Sbjct: 94 DSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQV 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,423,735
Number of Sequences: 37866
Number of extensions: 4864649
Number of successful extensions: 14941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 14530
Number of HSP's gapped (non-prelim): 216
length of query: 3174
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3053
effective length of database: 13,665,732
effective search space: 41721479796
effective search space used: 41721479796
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.