BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] (410 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] 852 0.0 gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens] 525 e-149 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 77 4e-14 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 77 4e-14 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 74 2e-13 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 72 7e-13 gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 70 3e-12 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 69 6e-12 gi|14670268 RD RNA-binding protein [Homo sapiens] 69 8e-12 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 67 3e-11 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 63 6e-10 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 63 6e-10 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 62 7e-10 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 61 2e-09 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 59 1e-08 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 58 1e-08 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 58 1e-08 gi|213385278 TNF receptor-associated factor 3 interacting protei... 58 1e-08 gi|20070262 TNF receptor-associated factor 3 interacting protein... 58 1e-08 gi|125988409 RED protein [Homo sapiens] 57 2e-08 gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 55 2e-07 gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 55 2e-07 gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 55 2e-07 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 55 2e-07 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 2e-07 gi|10190682 chromobox homolog 8 [Homo sapiens] 55 2e-07 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 2e-07 gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 53 6e-07 gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 52 1e-06 gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 51 2e-06 >gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] Length = 410 Score = 852 bits (2202), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE Sbjct: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR Sbjct: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180 Query: 181 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY 240 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY Sbjct: 181 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY 240 Query: 241 YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSGKWL 300 YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSGKWL Sbjct: 241 YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSGKWL 300 Query: 301 LTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTDGAA 360 LTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTDGAA Sbjct: 301 LTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTDGAA 360 Query: 361 ATFACLLVIMYGASVVLALRSYREQKRYKGSREQPGSYSDAPEYLWSGTL 410 ATFACLLVIMYGASVVLALRSYREQKRYKGSREQPGSYSDAPEYLWSGTL Sbjct: 361 ATFACLLVIMYGASVVLALRSYREQKRYKGSREQPGSYSDAPEYLWSGTL 410 >gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens] Length = 401 Score = 525 bits (1351), Expect = e-149 Identities = 256/392 (65%), Positives = 290/392 (73%), Gaps = 3/392 (0%) Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE Sbjct: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR Sbjct: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180 Query: 181 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY 240 EAEGLLECHKCKYLCTGR Q++EV+LN ++L C SY G++ S GG + + Sbjct: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240 Query: 241 ---YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSG 297 YS F+G + E+ +QLD Q+ L+ P++ +A S L L + G Sbjct: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300 Query: 298 KWLLTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTD 357 L+TE +L A GY + Y H + CK R+ LY KG + C G D Sbjct: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360 Query: 358 GAAATFACLLVIMYGASVVLALRSYREQKRYK 389 A FA L ++++ VLA++ YR+ ++ K Sbjct: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLK 392 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 76.6 bits (187), Expect = 4e-14 Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 15/176 (8%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 RE R R RER+ R ++ R +R RDR D ++R D +R RD DRD ER +R+ Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127 +R R+R++ R+RERER+ +R R+ R+ E+ R+ R +D R Sbjct: 380 DRSRSREKSRDRERERERERERERERERERERERERERERERERE-REKDKKRDRE---- 434 Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAE 183 E E +RK + R+ E E + L + R++ Y+ EAE Sbjct: 435 --------EDEEDAYERRKLE--RKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480 Score = 64.7 bits (156), Expect = 1e-10 Identities = 30/96 (31%), Positives = 54/96 (56%) Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 +E+ G +E + E++ R + R R+R + R+R + R R+ +RD + Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350 Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96 RD+ ++ +RDR+R+R+R+R+RER DR R R+ Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386 Score = 51.6 bits (122), Expect = 1e-06 Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 5/107 (4%) Query: 17 RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG-DRDPERDQERDGNRDRNRDR 75 RD ++ ++G+ ++ R RR+R + R R+ +R+ ER++ER+ +++ R+R Sbjct: 285 RDTHKKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERER 343 Query: 76 ERERERERD--PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 ERER+R+RD +R RD RD R E +SR+R+ +R Sbjct: 344 ERERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSR 389 Score = 47.0 bits (110), Expect = 3e-05 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 30/124 (24%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E S + R+R RE+ R ++ R +R R+R + R+R + R R+ ++D +R Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431 Query: 62 DQERDGN----------------------------RDRNRDRERERERERDPDRGPRRDT 93 D+E D R+R + RE E+E ER+ +R RR+ Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER--RREM 489 Query: 94 HRDA 97 ++A Sbjct: 490 AKEA 493 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 27/117 (23%) Query: 2 EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60 +D S +RE R R RER+ R ++ R +R R+R + R+R + +++RD + D E Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438 Query: 61 --------------------------RDQERDGNRDRNRDRERERERERDPDRGPRR 91 +ER R+ ++ ERE ER R+ + +R Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495 Score = 33.9 bits (76), Expect = 0.27 Identities = 46/214 (21%), Positives = 68/214 (31%), Gaps = 52/214 (24%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-------------------- 50 R R RER+ R ++ R +R R+R D +R R D Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458 Query: 51 ------------RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP--------- 89 + R+ +++ ER++ER + R +E + D DR Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518 Query: 90 -------RRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQ 142 ++ D R E E+ RQ +G D A EA Q Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHP----DPDAELQRMEQEAERRRQ 574 Query: 143 PQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176 PQ K +P E E + P EE E Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608 Score = 31.6 bits (70), Expect = 1.4 Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 22/107 (20%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-----------------PGDPRRK 44 +DP R + R RD + D+ DR R++ P ++ Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADE---RDRKREKEELEEIRQRLLAEGHPDPDAELQR 564 Query: 45 RSSDGNRRRDGD--RDPERDQERDGNRDRNRDRERERERERDPDRGP 89 + RRR ++PE ++E + +++ RE E E +P++ P Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 76.6 bits (187), Expect = 4e-14 Identities = 55/167 (32%), Positives = 79/167 (47%), Gaps = 19/167 (11%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 R+ RAR R+R+ R R +R R+R D R++ + R R +R+ ER++ERD Sbjct: 672 RDERARERDRERER------DRERERERERERDREREKERELERERAREREREREKERDR 725 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127 RDR+RD +RERERER+ DR R+ R+ R E + + R R+ AR + Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785 Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREE 174 WE + KG RR E +R PR G +E Sbjct: 786 R---QRDWEDKD------KGRDDRREKREEIREDR----NPRDGHDE 819 Score = 67.0 bits (162), Expect = 3e-11 Identities = 53/166 (31%), Positives = 76/166 (45%), Gaps = 35/166 (21%) Query: 7 ARE-PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRS-SDGNRRRDGDRDPERDQE 64 ARE R R +ERD R D R +R R+R + R+R + R R+ +R+ ER++E Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771 Query: 65 RDGNRDRNRDRERERERE-------RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 R+ R R RD+ERER+R+ RD R R + D PR G R+S+ R Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG-----HDERKSKKRY 826 Query: 118 GARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERY 163 G P+P ++P +RR E P S+ Y Sbjct: 827 RNEG---------SPSPRQSP------------KRRREHSPDSDAY 851 Score = 66.2 bits (160), Expect = 5e-11 Identities = 38/113 (33%), Positives = 62/113 (54%), Gaps = 6/113 (5%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 R+ R R D ++ R DR R+R + R+R + +R R+ +R+ ER++ R+ Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R+R ++R+RER+R+RD DR R+ RD R E E+ R+ R R+ R Sbjct: 716 EREREKERDRERDRDRDHDRERERERERD---REKER---EREREERERERER 762 Score = 56.6 bits (135), Expect = 4e-08 Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 10/122 (8%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRD-RPGDPRRKRSSDGNRRRDG-------DRDP 59 R+ R + R+ RR H ++ R +R RD RP P R + + RD DR Sbjct: 611 RDNRDQARDSSFERR-HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669 Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRDG 118 +R ER RDR R+R+RERERER+ +R R+ R+ RA E + + R RD Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729 Query: 119 AR 120 R Sbjct: 730 DR 731 Score = 55.1 bits (131), Expect = 1e-07 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 10/118 (8%) Query: 8 REPRARPRERDPGRRPHPDQG-RTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66 R+ R R GR ++ R +R DR D R +R+ + +R R+ DR+ ER++ER+ Sbjct: 637 RDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERE 696 Query: 67 GNRDRNRDRE----RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 +R+R ++RE R RERER +R RD RD R +H + + R R+ R Sbjct: 697 RDREREKERELERERARERER--EREKERDRERD---RDRDHDRERERERERDREKER 749 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 12/122 (9%) Query: 5 SGAREPRARPRERDP---GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 SG+ + R R +ERD R ++ T R DR D R+ D +R R+ +R+ ER Sbjct: 1290 SGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERER 1349 Query: 62 DQERDGNRDRNR------DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 D+ RD +R+R R +R+R+R+R+R + R GEH E+ +S + Sbjct: 1350 DKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEH---ERDLESTS 1406 Query: 116 RD 117 RD Sbjct: 1407 RD 1408 Score = 51.6 bits (122), Expect = 1e-06 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 7/96 (7%) Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPR----DR-PGDPRRKRSSDGNRRRDGDR 57 D +R +R + R+ H G R R DR D R+R R+R+ DR Sbjct: 1266 DRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDR 1325 Query: 58 DPERDQERDGNRDRNRDRERERERE--RDPDRGPRR 91 D ++D R+ +RDR R+RERERER+ RD DR R Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1361 Score = 49.7 bits (117), Expect = 5e-06 Identities = 40/119 (33%), Positives = 56/119 (47%), Gaps = 15/119 (12%) Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69 PR R R+ GR H ++HDR +R D R KR +R +D + E +Q++ +R Sbjct: 389 PRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR----DREKDSREEREYEQDQSSSR 444 Query: 70 DRNRDRE----RERERERDP-DRGPRRDTH-----RDAGPRAGEHGVWEKPRQSR-TRD 117 D DRE R+R RD DR RD+ R+ + + PR SR TRD Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRD 503 Score = 43.5 bits (101), Expect = 3e-04 Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 21/116 (18%) Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 D RE RER +R R+R + R+R + R RD +R+ +RD Sbjct: 744 DREKEREREREERER--------------ERERERERERERERERERARERDKERERQRD 789 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTH--RDAGPRAGEHGVWEKPRQSRTR 116 E ++D+ RD RE+ E DR P RD H R + R G PRQS R Sbjct: 790 WE---DKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGS-PSPRQSPKR 840 Score = 42.7 bits (99), Expect = 6e-04 Identities = 45/191 (23%), Positives = 77/191 (40%), Gaps = 19/191 (9%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R RER+ R ++ R D+ R+R D K +RR + E RDG+ + Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819 Query: 71 RNRDRERERERERDPDRGPRR--------DTHRDAGPRAGEHGVWE---KPRQSRTRDGA 119 R + E P + P+R D + + +H + +P++SR+ + Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879 Query: 120 RGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQ 179 LT D W+ E +P+RK + RR E E + R E +E + Sbjct: 880 H-LTEDR-----QGRWK-EEDRKPERK-ESSRRYEEQELKEKVSSVDKQREQTEILESSR 931 Query: 180 SEAEGLLECHK 190 A+ ++ H+ Sbjct: 932 MRAQDIIGHHQ 942 Score = 36.6 bits (83), Expect = 0.042 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 15/109 (13%) Query: 57 RDPERDQERDGNRDRNRDRERERERERDP--------DRGPRRDTHRDAGPRAG----EH 104 +D ++ RDG +DR RD ER+RE+ P P H + ++G H Sbjct: 287 KDRIEEKTRDG-KDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRH 345 Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR 153 PR+ RT + T +P+ + PQRK P R R Sbjct: 346 S--PSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392 Score = 35.8 bits (81), Expect = 0.072 Identities = 45/168 (26%), Positives = 65/168 (38%), Gaps = 24/168 (14%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPE 60 ED G R+ RE R DQ + D DR P D R +R + R R RD Sbjct: 418 EDTRGKRDREKDSREE---REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSR 474 Query: 61 --------RDQERDGNRDRN-------RDRERERERE-RDPDRGPRRDTHRDAGPRAGEH 104 RD RD R+ RD R+RE RD R + DT+ + G + Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHR--KEDTYPEESRSYGRN 532 Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPP--GPAPWEAPEPPQPQRKGDPG 150 + E+ ++ R+ +R + G + PE P+ +G G Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRG 580 Score = 33.5 bits (75), Expect = 0.36 Identities = 40/150 (26%), Positives = 49/150 (32%), Gaps = 57/150 (38%) Query: 8 REPRARPRERDPG--------------------------------RRPHPDQGRTHDRPR 35 RE R +PR P R P P RT P Sbjct: 308 REKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPL 367 Query: 36 DRP---------GDPRRKRSSDGNR---RRDG-----------DRDPERDQERDGNRDRN 72 R P+RK+S +R R G DR ER ++ G RDR Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427 Query: 73 RDRERERERERDPDRGPRRDTHRDAGPRAG 102 +D ERE E+ D+ RD D PR G Sbjct: 428 KDSREEREYEQ--DQSSSRDHRDDREPRDG 455 Score = 33.1 bits (74), Expect = 0.47 Identities = 33/99 (33%), Positives = 46/99 (46%), Gaps = 15/99 (15%) Query: 39 GDPRRKRSSDGNRRRDGDR---DPERDQE---RDGNRD-RNRDRER-----ERERERDPD 86 G+P R SSD R PE D++ R G+ D R+R +ER +RERER+ Sbjct: 1257 GEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERR 1316 Query: 87 RGPRRDTHRDAG---PRAGEHGVWEKPRQSRTRDGARGL 122 +R+ RDA PR + + + R RD R L Sbjct: 1317 DTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDL 1355 Score = 29.6 bits (65), Expect = 5.2 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 33 RPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRD 92 R +RP R+R N+R+D D +P++ + + ++ R R RE++ + + Sbjct: 76 RSPERPTGDLRERMK--NKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER 133 Query: 93 THRDAGPRAGEHGV-WEKPR 111 T P + E V WE R Sbjct: 134 T-----PESEEENVEWETNR 148 Score = 29.6 bits (65), Expect = 5.2 Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 40 DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR-DRERERERERD 84 D RSS R R +RD RDQ RD + +R +R+R RERD Sbjct: 594 DSWETRSSYPERDRYPERD-NRDQARDSSFERRHGERDRRDNRERD 638 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 8/153 (5%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 + R RERD GR D+ R +R R D +R ++ R RD +R+ ++++E + +RD Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190 Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKP-RQSRTRDGARGLTWDAAAP 129 R RD E+ERER+ D +R +R T + G E R+ R RD RG D Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER- 249 Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162 + E + +RK + + R E + +R Sbjct: 250 ------DRKEERKKERKKERKKERKEKKKEEKR 276 Score = 63.5 bits (153), Expect = 3e-10 Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 11/132 (8%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNR---------- 51 +D G RE RERD R ++ DR R R + R+R +D R Sbjct: 159 KDRDGQRETETE-RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217 Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111 +R+ DR+ ER+ +R R R+RDR +ER+RERD +++ ++ E EK R Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277 Query: 112 QSRTRDGARGLT 123 + + R G++ Sbjct: 278 EDKKRKWGEGIS 289 Score = 60.8 bits (146), Expect = 2e-09 Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 5/121 (4%) Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 D R+ R +E++ R ++ +R R+R R+R D R R+ DRD E++ Sbjct: 93 DRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKE 152 Query: 63 QERDGNRDRN--RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGA 119 +ER +DR+ R+ E ERER+R+ ++ R+T RD + E+ RQ+ R RD Sbjct: 153 RERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK--ERERQTDRERDRQ 210 Query: 120 R 120 R Sbjct: 211 R 211 Score = 56.6 bits (135), Expect = 4e-08 Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 12/88 (13%) Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG--------DRDPERDQE 64 R RERD R ++ R DR RDR RR++ + NR RD DR+ E+ + Sbjct: 77 RQRERDRVREK-TEKERDRDRKRDRE---RRRKEKETNRNRDREKQTEIERDREREKQKG 132 Query: 65 RDGNRDRNRDRERERERERDPDRGPRRD 92 R+ RDR R+RER+R+RE++ +R +D Sbjct: 133 RERERDRGRERERDRDREKERERQTEKD 160 Score = 52.4 bits (124), Expect = 7e-07 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 7/110 (6%) Query: 14 PRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR 73 PR G+ G R RDR + + ++ D +R+RD +R R +E++ NR+R+R Sbjct: 60 PRSWGLGQAHKDADGDDRQRERDRVRE-KTEKERDRDRKRDRER---RRKEKETNRNRDR 115 Query: 74 DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT---RDGAR 120 +++ E ER+R+ ++ R+ RD G EK R+ +T RDG R Sbjct: 116 EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 72.4 bits (176), Expect = 7e-13 Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 7/167 (4%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R RER+ ++ R DR RDR R+R R R +R+ ERD+ER+ RD Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267 Query: 71 RNRDRE-RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129 R+RDR+ R++ERER DR +R T RD E + ++ R R+ R + Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDR-----ETERKRERQRERERERERNRKRERERE 322 Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176 E + + K +R+ ++E ER T R GR + E Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERN-RQTGREGRRQAE 368 Score = 68.6 bits (166), Expect = 1e-11 Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 34/189 (17%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R RER+ R+ ++ +R RDR D +++R + RDG R+ E+ +ER+ +R+ Sbjct: 369 RERERERERDRQSARER---EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425 Query: 71 --RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG---------A 119 R R+R RERE+++ +R R T R AG + ++ P R G Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485 Query: 120 RGLTW-----DAAAPPGPAPWEAP--------------EPPQPQRKGDPGR-RRPESEPP 159 RG+ W D A PW P EP +++G G RRP Sbjct: 486 RGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFG 545 Query: 160 SERYLPSTP 168 +E L P Sbjct: 546 TENPLSQAP 554 Score = 66.6 bits (161), Expect = 4e-11 Identities = 39/114 (34%), Positives = 65/114 (57%), Gaps = 5/114 (4%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 R + R R+ D R+ ++ R +R R+R + R+R + R R+ +R+ ER+++R+ Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGAR 120 RDR ++RER+R+R+ + DR R T R+ G R E E+ R+ R R AR Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGRE-GRRQAER---ERERERERDRQSAR 383 Score = 64.7 bits (156), Expect = 1e-10 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 9/117 (7%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER-- 65 R + R R+RD R D+ + +R DR D R+R + NR+++ +R+ ER+ ER Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERD--RQREKERNRQKERERETEREGERGR 139 Query: 66 ----DGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRD 117 DG R+R R R+ E+ERER DR +R T R+ R E E+ + R R+ Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196 Score = 63.2 bits (152), Expect = 4e-10 Identities = 33/116 (28%), Positives = 59/116 (50%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E + + R R ++R R H ++ R ++ R+R D R R + R R +R+ E Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131 Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 ++E + RDR D +RERER+RD ++ R T R+ + + E+ R+ ++ Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187 Score = 61.6 bits (148), Expect = 1e-09 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 +D G R R +ER+ R + T DR R+R + R R D +R R DR+ ER Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERET-DRKRERRREKDRHRKRDRHRERQRDREKER 105 Query: 62 ----DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 D+ERD R++ R+R++ERERE + + RD D EK R+ +T Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163 Score = 61.2 bits (147), Expect = 2e-09 Identities = 27/107 (25%), Positives = 60/107 (56%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R RE++ R+ ++ R ++ R+R + R+ +G R RD D +R++ER + + Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156 Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 + R+R+ +RER+R +R +++ R+ + ++ ++++T D Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 12/119 (10%) Query: 2 EDPSGAREPRARPRERDPGRRP---HPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD 58 E +E R R R+R+ + H ++GR +R R+ + RKR +D R RD R Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD--RERDRQRK 237 Query: 59 PERDQERDGNRDR--NRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 ER++E+ R+R R+ ER++ERER+ DR RD + R ++ RQ RT Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ-----TDRKRQRRT 291 Score = 60.8 bits (146), Expect = 2e-09 Identities = 34/113 (30%), Positives = 54/113 (47%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 + R R RER+ R ++ R +R R+R + R R + R+R + +R++ R Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R+ R ERERERER+ DR R+ R + + + + RDG R Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412 Score = 60.5 bits (145), Expect = 3e-09 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R RERD R ++ + +R +R G+ R R +DG R R+ RD E+++ER D Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ--TD 164 Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R R R+ ER R+++ +R R R+ + + E R R+ R Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 RE R RE D R ++ R R RDR + +R R + R+ D +RD +R++ER+ Sbjct: 66 REKRQTERETDRKRERRREKDR--HRKRDRHRERQRDREKERERQTDRERDRQREKERNR 123 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 ++R R+ ERE ER RD +R+ R ++ RQ +T Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 12/115 (10%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R RE + GR D R +R RD + R+R +D R+R +R+ ++++ER+ NR Sbjct: 129 RETEREGERGRDRQTDGQRERERQRD--AEKERERQTDRERQRQTERNRQKEREREKNRQ 186 Query: 71 RNRDRERERERE-----RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R+RER+RE+E R +RG R+ R+ E K + R RD R Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERET-----ETETERKRQTDRERDRQR 236 Score = 56.6 bits (135), Expect = 4e-08 Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 8/182 (4%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E + + R R+R+ R+ + R +R R+R + R+R + R+R+ +RD E+ Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339 Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121 ++ER R DRER R+ R+ R R+ R+ E+ + R RD R Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERER--ERDRQSAREREERERDRDRDRQ 397 Query: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSE 181 + + + QR+ + R ESE ER + GRE Q++ Sbjct: 398 KERERQTEKDR---DGQRETEKQREREKDR---ESERGRERGREREKQKGRERDRERQTD 451 Query: 182 AE 183 + Sbjct: 452 RQ 453 Score = 52.0 bits (123), Expect = 1e-06 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 5/110 (4%) Query: 17 RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRE 76 R PG + P + +D GD R + RR R ER+ +R R R +DR Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88 Query: 77 RE----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT-RDGARG 121 R+ RER+RD ++ R T R+ + + +K R+ T R+G RG Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138 Score = 45.8 bits (107), Expect = 7e-05 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 13/75 (17%) Query: 32 DRPRDRPGD---PRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDR-------ERERER 81 D R RPG PRR+ ++ DGD +R++ R R+R R++ +R+RER Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRER 81 Query: 82 ERDPDRGPRRDTHRD 96 R+ DR +RD HR+ Sbjct: 82 RREKDRHRKRDRHRE 96 >gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] Length = 2240 Score = 70.5 bits (171), Expect = 3e-12 Identities = 52/127 (40%), Positives = 70/127 (55%), Gaps = 11/127 (8%) Query: 1 MEDPSG-AREPRARPRERDPGRRPHPDQGRTHDRPR--DRPGDPRRKRSSDGNRRRDGDR 57 +E+P R R RER+ GR + + R DRPR DR D R D NR R +R Sbjct: 2100 LEEPDAQGRASEDRRRERERGR--NWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANR 2157 Query: 58 DPERDQER----DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS 113 D ER+ +R D +R+R+R+RERER+R RD DR R+ RD R E G K R S Sbjct: 2158 DREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKA-RDRERGRDRKDR-S 2215 Query: 114 RTRDGAR 120 ++++ AR Sbjct: 2216 KSKESAR 2222 Score = 67.4 bits (163), Expect = 2e-11 Identities = 44/107 (41%), Positives = 56/107 (52%), Gaps = 6/107 (5%) Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72 RPRE D R D R DR R+R + R+R +D R ++ DR ER + R+ RDR Sbjct: 2131 RPREWD--RHRDKDSSRDWDRNRERSANRDREREAD--RGKEWDRSRERSRNRERERDRR 2186 Query: 73 RDRERERERERDPDRGPRRDTHRDAGPR--AGEHGVWEKPRQSRTRD 117 RDR+R R RERD D+ R+ RD R + E KP SR D Sbjct: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233 Score = 50.8 bits (120), Expect = 2e-06 Identities = 37/91 (40%), Positives = 48/91 (52%), Gaps = 9/91 (9%) Query: 13 RPRER---DPGRRP--HPD-QGR-THDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65 R RER P +P PD QGR + DR R+R R D +R R+ DR ++D R Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145 Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRD 96 D +R+R R R+RERE DRG D R+ Sbjct: 2146 DWDRNRERSANRDRERE--ADRGKEWDRSRE 2174 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 9/116 (7%) Query: 19 PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP------ERDQERDGNRDRN 72 PG+ P D R+ G R ++ +G +R D P E D + + DR Sbjct: 2055 PGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRR 2114 Query: 73 RDRERERE--RERDPDRGPRRDTHRDA-GPRAGEHGVWEKPRQSRTRDGARGLTWD 125 R+RER R RERD DR D HRD R + + R R+ RG WD Sbjct: 2115 RERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWD 2170 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 69.3 bits (168), Expect = 6e-12 Identities = 34/86 (39%), Positives = 52/86 (60%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R R+R+ R+ ++ + DR R R D R+R+ G R RD + ERD+ER+ R Sbjct: 80 RERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQ 139 Query: 71 RNRDRERERERERDPDRGPRRDTHRD 96 R R+R+R+RER+R+ DR +R R+ Sbjct: 140 RERERQRQRERKRETDRERQRWAERE 165 Score = 68.6 bits (166), Expect = 1e-11 Identities = 35/84 (41%), Positives = 50/84 (59%) Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72 R ER R+ ++ R DR RD+ D RKR +D NR R+ ERD++ + RDR Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133 Query: 73 RDRERERERERDPDRGPRRDTHRD 96 R+R+R+RERER R +R+T R+ Sbjct: 134 RERQRQRERERQRQRERKRETDRE 157 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/88 (43%), Positives = 51/88 (57%), Gaps = 4/88 (4%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R +ERD R+ + R +R R+R RKR +D R RD DRD ER +E D NR+ Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTD--RERDKDRDRERKRETDRNRE 113 Query: 71 RNRD--RERERERERDPDRGPRRDTHRD 96 RNR RER+++ ER+ DR R R+ Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRE 141 Score = 64.7 bits (156), Expect = 1e-10 Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 1/156 (0%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 RE R R R+R R D+ + +R ++R +R+R ++ R +R +R+++R Sbjct: 33 RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDA 126 +R+R++DR+RER+RE D +R R R+ + E+ RQ R R+ R Sbjct: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKR 152 Query: 127 AAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162 W E + +RK + + R E + +R Sbjct: 153 ETDRERQRWAEREERKKERKKERKKERKEKKKEEKR 188 Score = 59.7 bits (143), Expect = 5e-09 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 14/129 (10%) Query: 2 EDPSGAREPRARPRERD-------PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD 54 E G R R R+R+ R D+ R DR DR + R++ D R+R+ Sbjct: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69 Query: 55 GD--RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112 + R+ ER +ER R+R R +RER+++RD +R D +R+ + G E+ +Q Sbjct: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR----ERDKQ 125 Query: 113 S-RTRDGAR 120 + R RD R Sbjct: 126 TERERDRER 134 Score = 58.2 bits (139), Expect = 1e-08 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 5/86 (5%) Query: 16 ERDPGRRPHPDQGRTHDRPRDRPGD-----PRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 ER R+ D+G+ +R RDR + R R +R R+ DR +R++ER+ ++ Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 71 RNRDRERERERERDPDRGPRRDTHRD 96 R+R R+RERE ER+ +R R R+ Sbjct: 62 RDRQRQRERETERETERQRERQRQRE 87 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 8/117 (6%) Query: 11 RARPRERDPGRRPHPDQGRTHDRP-------RDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63 R R RE D G+ ++ R +R R R D R+R +R ++ +R ERD+ Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64 Query: 64 ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 +R R+ R+ ER+RER+R +R + D RD R E + R R G R Sbjct: 65 QRQRERETERETERQRERQRQRERKRQTDRERDK-DRDRERKRETDRNRERNRKGGR 120 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 18/97 (18%) Query: 42 RRKRSSDGNRRRDGDRDPERDQERDG-----NRDRNRDR------------ERERERERD 84 +R+R + +R ++ +R+ +R +ER+ NR R RDR ERER++ERD Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63 Query: 85 PDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGAR 120 R R+T R+ + E+ RQ+ R RD R Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDR 100 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 7/79 (8%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65 G + RERD R R R R+R RKR +D R+R +R+ ER +ER Sbjct: 119 GRERDKQTERERDRERE------RQRQRERERQRQRERKRETDRERQRWAERE-ERKKER 171 Query: 66 DGNRDRNRDRERERERERD 84 R + R +++ E+ R+ Sbjct: 172 KKERKKERKEKKKEEKRRE 190 >gi|14670268 RD RNA-binding protein [Homo sapiens] Length = 380 Score = 68.9 bits (167), Expect = 8e-12 Identities = 47/107 (43%), Positives = 58/107 (54%), Gaps = 19/107 (17%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E+ SGA + PR R + R+H+R RDR D R R RD DRD ER Sbjct: 171 EERSGAHSSASPPRSRS--------RDRSHERNRDRDRDRERDRD------RDRDRDRER 216 Query: 62 DQERDGNRDRNRDRERERERERDPDR---GPRRDTHRDAGPRAGEHG 105 D++RD RDR+RDRER+R+RERD DR GP R + RA G Sbjct: 217 DRDRD--RDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261 Score = 66.6 bits (161), Expect = 4e-11 Identities = 35/91 (38%), Positives = 51/91 (56%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E+ G PR D G + PR R D +R+ D +R R+ DRD +R Sbjct: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210 Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRD 92 D++R+ +RDR+RDR+R+RER+RD +R RD Sbjct: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRD 241 Score = 49.3 bits (116), Expect = 6e-06 Identities = 27/72 (37%), Positives = 37/72 (51%) Query: 25 PDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERD 84 P G R D + R S + R RD ++ RD +RDR RDR+R+R+R+R+ Sbjct: 156 PGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRE 215 Query: 85 PDRGPRRDTHRD 96 DR RD RD Sbjct: 216 RDRDRDRDRDRD 227 Score = 45.4 bits (106), Expect = 9e-05 Identities = 26/84 (30%), Positives = 39/84 (46%) Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72 R RE P G PR + + + R +R ER+ +RDR+ Sbjct: 142 RLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD 201 Query: 73 RDRERERERERDPDRGPRRDTHRD 96 R+R+R+R+R+RD +R RD RD Sbjct: 202 RERDRDRDRDRDRERDRDRDRDRD 225 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 67.0 bits (162), Expect = 3e-11 Identities = 49/157 (31%), Positives = 71/157 (45%), Gaps = 13/157 (8%) Query: 11 RARPRERDPGR-RPHPDQGRTHDR--PRDRPGDPRRKRSSDGNRRRDG--DRDPERDQER 65 R R R R+ R R + +T DR RDR D R R D +R R+ DR+ ER +ER Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78 Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWD 125 + +RDR R+ ERER++ER+ DR D R V ++ R+ + G T Sbjct: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT-- 136 Query: 126 AAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162 + Q +R+ + GR R + ER Sbjct: 137 ------DRETDRERERQAERERETGRERKTEDRHRER 167 Score = 60.5 bits (145), Expect = 3e-09 Identities = 35/107 (32%), Positives = 52/107 (48%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R RERD R+ ++ R +R DR + R+R R + RD ER+++++ R+ Sbjct: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133 Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 R DRE +RERER +R R R E K + R R+ Sbjct: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180 Score = 55.5 bits (132), Expect = 9e-08 Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 14/107 (13%) Query: 20 GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--NRDRNRDRER 77 GR H + T DR R+R + R+R + + DR ERD++RD NR+R+RDRER Sbjct: 7 GRHTHTET-ETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDRER 64 Query: 78 E----------RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114 E RERERD DR + RD H ++ RQ + Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/89 (30%), Positives = 45/89 (50%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 R ++ +R R D+ R +R RDR + + R + R R+ DRD +R+ ER+ Sbjct: 33 RAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERER 92 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRD 96 +++R DR E +RER + + RD Sbjct: 93 DKERETDRHTETDRERQKQKEREMERVRD 121 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 6/100 (6%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66 A+E + R + R+ ++ R DR R+R R+ R RD DR E ++ERD Sbjct: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD 93 Query: 67 GNRDRNR----DRERERERERDPDRGPRRDTHRDAGPRAG 102 R+ +R DRER++++ER+ +R RD R+ G Sbjct: 94 KERETDRHTETDRERQKQKEREMER--VRDREREKQKEMG 131 Score = 53.5 bits (127), Expect = 3e-07 Identities = 31/92 (33%), Positives = 54/92 (58%), Gaps = 8/92 (8%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRR-----KRSSDGNRRRDGDRDPERDQER 65 R R ++++ GR D R DR R+R + R +++ D +R R+ +R ER+++R Sbjct: 122 REREKQKEMGRERQTD--RETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179 Query: 66 DGN-RDRNRDRERERERERDPDRGPRRDTHRD 96 + R+R+ D ERER+RE D R +R++ R+ Sbjct: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211 Score = 52.0 bits (123), Expect = 1e-06 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 24/132 (18%) Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGN---- 68 R R+RD R D+ R ++ DR G+ +R+R D +R+R+ +R+ ++++E D + Sbjct: 46 RDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105 Query: 69 --------------RDRNRD------RERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108 RDR R+ RER+ +RE D +R + + R+ G Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165 Query: 109 KPRQSRTRDGAR 120 + + R R+ R Sbjct: 166 ERERERKRERER 177 Score = 50.4 bits (119), Expect = 3e-06 Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 10/76 (13%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR- 69 R RER+ GR + +T DR R+R + +R+R +R +R+ D ER+ R Sbjct: 146 RQAERERETGR-----ERKTEDRHRERERERKRERE---RKRETKERERHTDMERERQRE 197 Query: 70 -DRNRDRERERERERD 84 DR RDR+RE ERERD Sbjct: 198 TDRKRDRQRESERERD 213 Score = 36.6 bits (83), Expect = 0.042 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 10/83 (12%) Query: 47 SDGNRRRDGDRDPERDQERDGNRDRNRDRER---------ERERERDPDRGPRRDTHRDA 97 ++G +R +ER DR RDR + ER+R+RD +R RD R+ Sbjct: 5 TEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64 Query: 98 GPRAGEHGVWEKPRQSRTRDGAR 120 + G ++ R+ R RD R Sbjct: 65 EKQTDREGERQRERE-RDRDRQR 86 Score = 30.8 bits (68), Expect = 2.3 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 26/151 (17%) Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERD---PDRGPRRDTHRDAGPRAGEHGVWE 108 + +G + D R+R R+ +RER+R ++ DR RD RD E Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63 Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR-PESEPPSERYLPST 167 + +Q+ R+G R Q +R+ D R+R E E ER Sbjct: 64 REKQT-DREGER---------------------QRERERDRDRQRETERERDKERETDRH 101 Query: 168 PRPGREEVEYYQSEAEGLLECHKCKYLCTGR 198 RE + + E E + + + K GR Sbjct: 102 TETDRERQKQKEREMERVRDREREKQKEMGR 132 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R + RER+ R ++G+ DR ++R D + + D R R+ + + +RD+E++ +D Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454 Query: 71 RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123 + ++RE++R +E D R P R + R+ + +S +R T Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514 Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176 + P+P + + + K D R E E + S R G+E++E Sbjct: 515 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568 Score = 57.8 bits (138), Expect = 2e-08 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%) Query: 8 REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 R+ R+R RD + ++ + DR ++R + R++ + + +D D++ E+D Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96 +E+D +DR R+RE+E E++RD ++ +D ++ Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458 Score = 57.4 bits (137), Expect = 2e-08 Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%) Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64 S +R+ R RE+ + ++ R +R R++ + ++R + +R ++ ++D E+D+E Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430 Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 +D R+R ++ E++R++E++ ++ ++ +D E +K ++SRT Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 479 Score = 55.8 bits (133), Expect = 7e-08 Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%) Query: 11 RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57 R+R ++R + PH + ++ +R RD+ D R K R + +R ++ +R Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401 Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96 + ER++E++ ++++RD+ERE++RE+D ++ R+ ++ Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440 Score = 46.6 bits (109), Expect = 4e-05 Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%) Query: 5 SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60 S A EP + + ER GR R+H R + R RRKRS +R R +R Sbjct: 290 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 343 Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118 R ++R ++ ++ R + RER + R RD +D + E V EK R+ R R+ Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403 Query: 119 AR 120 R Sbjct: 404 ER 405 Score = 39.3 bits (90), Expect = 0.007 Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%) Query: 5 SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59 S +R PR R R P R + + ++ RD + R + S R+ DRD Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563 Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106 + E +N +E+E ++PD ++ PR E+ + Sbjct: 564 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R + RER+ R ++G+ DR ++R D + + D R R+ + + +RD+E++ +D Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338 Query: 71 RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123 + ++RE++R +E D R P R + R+ + +S +R T Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398 Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176 + P+P + + + K D R E E + S R G+E++E Sbjct: 399 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452 Score = 57.8 bits (138), Expect = 2e-08 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%) Query: 8 REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 R+ R+R RD + ++ + DR ++R + R++ + + +D D++ E+D Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96 +E+D +DR R+RE+E E++RD ++ +D ++ Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342 Score = 57.4 bits (137), Expect = 2e-08 Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%) Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64 S +R+ R RE+ + ++ R +R R++ + ++R + +R ++ ++D E+D+E Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314 Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115 +D R+R ++ E++R++E++ ++ ++ +D E +K ++SRT Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 363 Score = 55.8 bits (133), Expect = 7e-08 Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%) Query: 11 RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57 R+R ++R + PH + ++ +R RD+ D R K R + +R ++ +R Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285 Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96 + ER++E++ ++++RD+ERE++RE+D ++ R+ ++ Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324 Score = 46.6 bits (109), Expect = 4e-05 Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%) Query: 5 SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60 S A EP + + ER GR R+H R + R RRKRS +R R +R Sbjct: 174 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 227 Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118 R ++R ++ ++ R + RER + R RD +D + E V EK R+ R R+ Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287 Query: 119 AR 120 R Sbjct: 288 ER 289 Score = 39.3 bits (90), Expect = 0.007 Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%) Query: 5 SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59 S +R PR R R P R + + ++ RD + R + S R+ DRD Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447 Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106 + E +N +E+E ++PD ++ PR E+ + Sbjct: 448 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 62.4 bits (150), Expect = 7e-10 Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 15/121 (12%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQERDGN 68 R R R+R R D+ DR R R D R+R D +R+R+ GDRD E + ER Sbjct: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125 Query: 69 RDRNRDRERERERER--------DPDRGPRRDTHRDAGPRAGEHGVW-----EKPRQSRT 115 R+R RDR+RE++RER D DR + RD GE + E+ +Q T Sbjct: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185 Query: 116 R 116 R Sbjct: 186 R 186 Score = 59.3 bits (142), Expect = 6e-09 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63 P+ RE R R RER+ R+ ++ R DR ++ D +RKR + R RD DR ER Sbjct: 54 PAIIRE-RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112 Query: 64 ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG 98 +RD + R ERER+R+R ++ R R+ G Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIG 147 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 + + R RE+D D+ R DR R R D RKR G+R R+ + + + ++ER Sbjct: 71 KRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQR 130 Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111 +R R +DRER+R+RE D+ +T +D R E G E+ R Sbjct: 131 DRKREKDRERQRQREIGIDKDREIETEKDR-DREREMGETERYR 173 Score = 55.5 bits (132), Expect = 9e-08 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 3/86 (3%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 +D RE R RD R + DR R+R R K + +R R +R+ +R Sbjct: 158 KDRDREREMGETERYRDRERERQKQRETRRDRDRERQ---REKEDRERDRDRQKEREKDR 214 Query: 62 DQERDGNRDRNRDRERERERERDPDR 87 +ER+ RDR+++R+RER+RE+D DR Sbjct: 215 YRERETGRDRDKERDRERQREKDRDR 240 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/108 (27%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD-GNRDRNR 73 R+R+ ++ R DR R++ + +R+R ++ R+ + + +RD+ER+ G +R R Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173 Query: 74 DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121 DRERER+++R+ R R+ R+ R + ++ + R R+ G Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221 Score = 52.8 bits (125), Expect = 6e-07 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 7/98 (7%) Query: 13 RPRERDPGRRP-HPDQGRTHDRPRDRPGDPRRKRSSDG-NRRRDGDRDPERDQERDGNRD 70 R RER+ G + D+ R + R+ D R+R + +R RD DR ER+++R R+ Sbjct: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219 Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108 RDR++ER+RER ++ R D P G WE Sbjct: 220 TGRDRDKERDRERQREKDRDRQKAIDCVP-----GRWE 252 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 15/139 (10%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSS-------DGNRRRDGDRDPERDQ 63 R R RE+D R+ + G DR + D R+R D R R R+ RD+ Sbjct: 130 RDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDR 189 Query: 64 ERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 +R+ R DR RDR+R++ERE+ DR R+T RD EK R + Sbjct: 190 DRERQREKEDRERDRDRQKEREK--DRYRERETGRDRDKERDRERQREKDRDRQKAIDCV 247 Query: 121 GLTWDA---AAPPGPAPWE 136 W+ A P WE Sbjct: 248 PGRWEVTVMAVDCVPGRWE 266 Score = 32.3 bits (72), Expect = 0.80 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 26/80 (32%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 +E R R R+R +++R D R R+ RD RD+ERD Sbjct: 197 KEDRERDRDR------------------------QKEREKDRYRERETGRD--RDKERDR 230 Query: 68 NRDRNRDRERERERERDPDR 87 R R +DR+R++ + P R Sbjct: 231 ERQREKDRDRQKAIDCVPGR 250 Score = 30.0 bits (66), Expect = 4.0 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 D R+ RERD R+ R DR R+R R + D R+R+ DRD ++ Sbjct: 188 DRDRERQREKEDRERDRDRQKE----REKDRYRERETGRDRDKERDRERQREKDRDRQK 242 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 5/123 (4%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQ 63 G R R GR + R+ R + GD RR RS D +RRR+ RD R + Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61 Query: 64 ERDG---NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 RD R R+R+R+R RER R R RR R G R+ K +++ R ++ Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121 Query: 121 GLT 123 T Sbjct: 122 EKT 124 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 21/148 (14%) Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74 RE R+ +GR+ R R R +R + D R R DRD R++ R ++ R+R Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62 Query: 75 RERE-----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129 R+R+ R RERD R RR RD R+SR+R R ++ Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDR-------------RRSRSRSRGRR---SRSSS 106 Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESE 157 PG + + + K D G E + Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKK 134 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/179 (19%), Positives = 73/179 (40%), Gaps = 17/179 (9%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--- 67 R+R RERD R + R R R R R + SS GN+ + + ++ DG Sbjct: 70 RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129 Query: 68 NRDRNRDR-ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDA 126 ++++ +D+ ++E E+E+D + + R W + ++ + + L + Sbjct: 130 SKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEI 189 Query: 127 AAPPGPAPW-------EAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYY 178 W + +P + +++G+ E P + Y+ +EEV+ + Sbjct: 190 EEMKQGKKWSLEDDDDDEDDPAEAEKEGN--EMEGEELDPLDAYMEEV----KEEVKKF 242 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 15/102 (14%) Query: 11 RARPRERDPGRRPHPDQGR---THDRPRDRPGDPRRKRSSDGNRRRDGDR-------DPE 60 R R R RD R D+ R + R RDR + RR RS D R R R P Sbjct: 49 RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPG 108 Query: 61 RDQERDGNRDRNRDR----ERERERERDPDRGPRRDTHRDAG 98 ++ NR R++++ E +E+++D D + +DAG Sbjct: 109 NKSKKTENRSRSKEKTDGGESSKEKKKDKD-DKEDEKEKDAG 149 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 58.5 bits (140), Expect = 1e-08 Identities = 56/171 (32%), Positives = 67/171 (39%), Gaps = 17/171 (9%) Query: 8 REPRARPRERDPG-RRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR--DGDRDPERDQE 64 R PR R + D G RR D R+ R D PRR D RR D DR P R + Sbjct: 1036 RGPR-RGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMD 1094 Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVW---EKPRQSRTRDG 118 D R D +R R D DRGP R+ D PR G + G W + R SR D Sbjct: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154 Query: 119 ARGLTWDAAAPPG-------PAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162 R + PG P W E + + G P RP E +R Sbjct: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDR 1205 Score = 57.8 bits (138), Expect = 2e-08 Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 17/183 (9%) Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN---RRRDGDRDPERDQERD 66 P R + D G D+ R R D PRR + D R D DR P R + D Sbjct: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDD 1076 Query: 67 GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVWEKPRQSRTRDGARGLT 123 R D +R R D DRGPRR D GPR G + G W R RG Sbjct: 1077 RGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRI--PRRG-- 1132 Query: 124 WDAAAPPGPAPWEAPEPPQPQRKGDPGR--RRPESEPPSERYLPSTPRPGREEVEYYQSE 181 A PW + + R+ D R RR + P + P G E E + E Sbjct: 1133 ----AEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP-WRPLVKPGGWREKEKAREE 1187 Query: 182 AEG 184 + G Sbjct: 1188 SWG 1190 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/120 (35%), Positives = 54/120 (45%), Gaps = 16/120 (13%) Query: 14 PRERDPGR----RPHPDQGRTHDRPRDRP---GDPRRKRSSDGNRRRDGDRDPERDQERD 66 PR D R RP G ++ + R G PR R S+ R+ DR+ ERD++ Sbjct: 1158 PRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSE---EREWDREKERDRDNQ 1214 Query: 67 GNRDRNRDRERERERERDPDRGPRRDTHRDAG----PRAGEHGVW--EKPRQSRTRDGAR 120 + ++D ERER+RERD DR R RD G A E W R R RD R Sbjct: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274 Score = 50.8 bits (120), Expect = 2e-06 Identities = 51/165 (30%), Positives = 60/165 (36%), Gaps = 17/165 (10%) Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRP---GD-----PRRKRSSDGNRRR-- 53 P E R P E++ R D+ R+H R +RP GD P + D RR Sbjct: 903 PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGM 962 Query: 54 DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG-------PRAGEHGV 106 D DR P R E D R D +R R D DR PRR D G R G+ Sbjct: 963 DDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGL 1022 Query: 107 WEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGR 151 E RT D RG GP A + R D R Sbjct: 1023 DEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDR 1067 Score = 50.4 bits (119), Expect = 3e-06 Identities = 51/146 (34%), Positives = 65/146 (44%), Gaps = 29/146 (19%) Query: 2 EDPSGAREPRARPR------ERDPGRRPHPDQ----GRTHDR-PRDRPGDPR-RKRSSDG 49 ED S R+ RPR +R+P RP D+ G DR PR P + R +R +D Sbjct: 926 EDRSHRRDEE-RPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADD 984 Query: 50 NR----RRDGDRDPER--DQERDGNRDRNRDR--------ERERERERDPDRGPRRDTHR 95 +R D DR P R D++R R + DR +R R D DRGPRR Sbjct: 985 DRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDD 1044 Query: 96 DAGPRAGEHGVWEKPRQSRTRDGARG 121 D GPR G G ++ R D RG Sbjct: 1045 DRGPRRG--GADDERSSWRNADDDRG 1068 Score = 47.8 bits (112), Expect = 2e-05 Identities = 53/196 (27%), Positives = 70/196 (35%), Gaps = 36/196 (18%) Query: 4 PSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 P G RE +AR P R P + R DR ++R D + + +D + R+ DR+ + D Sbjct: 1175 PGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVD 1234 Query: 63 QERDGNRDRN---------------RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVW 107 +E R R+ RD R +R+RD DR RD RD R Sbjct: 1235 REDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRER------- 1286 Query: 108 EKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPST 167 R R R G P E E +R D R E P R P Sbjct: 1287 RDLRDDRDRRGP------------PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPA 1334 Query: 168 PRPGREEVEYYQSEAE 183 RE + E E Sbjct: 1335 LSRDRERDRDREREGE 1350 Score = 44.3 bits (103), Expect = 2e-04 Identities = 47/154 (30%), Positives = 66/154 (42%), Gaps = 17/154 (11%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPG---DPRRKRSS--DGNRRRDGDRDPERD 62 RE + ER+ R D+ RPRD G P + SS D +RR D DRD +R Sbjct: 1216 REENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRR 1274 Query: 63 QERDGNRD--RNRDRERERERERDPDRGPRRD--THRDAGPRAGEHGVWEK------PRQ 112 +ERD RD RD +R+R P R R + + R A R + V E+ P Sbjct: 1275 RERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR-VEERDPPRRVPPP 1333 Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRK 146 + +RD R + A W A + + R+ Sbjct: 1334 ALSRDRERDRDREREGEKEKASWRAEKDRESLRR 1367 Score = 31.2 bits (69), Expect = 1.8 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 27/122 (22%) Query: 56 DRDPERDQER---DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112 +R+ R++ER D + R R +R+ E +GP D+ GP E W R+ Sbjct: 867 ERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKE---W---RR 920 Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGR 172 RD R + +P+R GD R P P +R PR G Sbjct: 921 GEGRDEDRS--------------HRRDEERPRRLGDDEDREPSLRPDDDR----VPRRGM 962 Query: 173 EE 174 ++ Sbjct: 963 DD 964 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 58.2 bits (139), Expect = 1e-08 Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 13/98 (13%) Query: 9 EPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG----DRDPERDQE 64 E R +ER+ R+ +Q + R++ + R R + +RR+ DR+ ER++E Sbjct: 1240 ERAERAKEREKRRK---EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE 1296 Query: 65 RD-GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRA 101 RD G+RDR+R+R+RER RERD RRDT R + R+ Sbjct: 1297 RDRGDRDRDRERDRERGRERD-----RRDTKRHSRSRS 1329 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 8/93 (8%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 E ++ R + ER+ R+ ++ R H R RDR + R+R R D DRD ER Sbjct: 1254 EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD-----RGDRDRDRER 1308 Query: 62 DQERDGNRDRNRDRERERERERDP---DRGPRR 91 D+ER RDR + R R R DRG RR Sbjct: 1309 DRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 5/86 (5%) Query: 35 RDRPGDPRRKRSSDGN---RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR- 90 R + + RRK + R ++ +R+ R ER+ R+ +R+R+RERERER+ DRG R Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303 Query: 91 RDTHRDAGPRAGEHGVWEKPRQSRTR 116 RD RD R E + R SR+R Sbjct: 1304 RDRERDR-ERGRERDRRDTKRHSRSR 1328 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER-DQER 65 A+E R +E++ + ++ +R R + RR+ S + +R R+ +R+ +R D++R Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR 1304 Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTH-RDAGPR 100 D RDR R RER+R + R R T RD G R Sbjct: 1305 DRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 19/168 (11%) Query: 5 SGAREPRARPRERDP---GRRPHPD---------QGRTHDRPRDRPGDPRRKRSSDGNRR 52 S + +R R R P G R H Q RTH PR RP R S +R Sbjct: 582 SSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRS 641 Query: 53 RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112 R R + + + +RD +DP G A P + V E + Sbjct: 642 RSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSG-----QEVATPPVPQLQVCEP--K 694 Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPS 160 RT + + + P A + QP+R E+EPP+ Sbjct: 695 ERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPA 742 Score = 36.2 bits (82), Expect = 0.055 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 9/101 (8%) Query: 9 EPRARPRERDPGRRPHPDQGRTHDRPRDRPGD-------PRRKRSSDGNRRRDGDRDPER 61 E + PR P P P Q H R R + R+R + R +R+ +R Sbjct: 1109 EEQGIPRPLHPPPPP-PVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR 1167 Query: 62 DQERDGNRDRNRDRERER-ERERDPDRGPRRDTHRDAGPRA 101 D+ R+G R R+R R+R R ER + ++ + P A Sbjct: 1168 DKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPA 1208 Score = 29.6 bits (65), Expect = 5.2 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 60 ERDQERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTR 116 ER +ER+ R + +ERE+E ER+ +R R+ R+ E+ R R Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302 Query: 117 DGAR 120 D R Sbjct: 1303 DRDR 1306 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 58.2 bits (139), Expect = 1e-08 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 10/120 (8%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPG-DPRRKRSSDGNRRRDGDRDPERDQERDGNR 69 R R R R H + R+ DR DR D R++ ++ RRRD D D ER ER+ R Sbjct: 323 RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKER 382 Query: 70 DRNRDRER---------ERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 +R+R+R + E++ + D D RD RD+ + R+ R+R +R Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR 442 Score = 46.2 bits (108), Expect = 5e-05 Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 21/140 (15%) Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR----------- 53 S +R+ + R+RD R ++GR DR D+ R++ + +R R Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399 Query: 54 ------DGDRDPERDQERDGNRDRNRDRERERERE---RDPDRGPRRDTHRDAGPRAGEH 104 D D RD +RD +++ R R RER+ R R + + + ++ +H Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459 Query: 105 GVWEKPRQS-RTRDGARGLT 123 K + + R+R G++G T Sbjct: 460 KNESKEKSNKRSRSGSQGRT 479 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 2/112 (1%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67 R R+ R P R P + R+H R R+ + R+R ER++ER Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317 Query: 68 NR--DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 +R DR +R R R RER R RD D R E + + R RD Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369 Score = 42.7 bits (99), Expect = 6e-04 Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 13/123 (10%) Query: 11 RARPRE-RDPGRRPHPDQGRTHDRPRDRPG--------DPRRKRSSDGNRRRDG----DR 57 + RPR+ + G+ + R +R R R PRR RS +R G DR Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293 Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117 + ER++ER ++RE+ER R R DRG R R ++ R RD Sbjct: 294 ELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRD 353 Query: 118 GAR 120 R Sbjct: 354 RER 356 Score = 42.4 bits (98), Expect = 8e-04 Identities = 21/88 (23%), Positives = 41/88 (46%) Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64 S R+ R+R R R+ G+R + ++ + KRS G++ R + + +E Sbjct: 430 SRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489 Query: 65 RDGNRDRNRDRERERERERDPDRGPRRD 92 +++++R R R +ER D +D Sbjct: 490 HSPSKEKSRKRSRSKERSHKRDHSDSKD 517 Score = 31.2 bits (69), Expect = 1.8 Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 11/99 (11%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-----------DGD 56 +E + R RD R ++ + R R+R R + + G R R + Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463 Query: 57 RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHR 95 ++ + R G++ R E+ ++RE P + R R Sbjct: 464 KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR 502 Score = 28.9 bits (63), Expect = 8.8 Identities = 13/60 (21%), Positives = 28/60 (46%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 +++ RE P + + R+ +R R + +S +RRR + E +++ N+D Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543 >gi|213385278 TNF receptor-associated factor 3 interacting protein 1 isoform 2 [Homo sapiens] Length = 625 Score = 58.2 bits (139), Expect = 1e-08 Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58 G E + R RD R ++ + +PR++ D + + + GNR R+G+R+ Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225 Query: 59 PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99 P+ ++++D GNR+R+RD E R+R+RERD D+G RD R Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282 Query: 100 RAGEHGVWEKPRQ 112 + GEH W+ R+ Sbjct: 283 KNGEHS-WDLDRE 294 Score = 56.6 bits (135), Expect = 4e-08 Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 39/212 (18%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65 G RE RA+ R R R R DR +R + RK + R DRD ERD+++ Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273 Query: 66 DGNRDRNR--------DRERERERERDPD-------------------RGPRRDTHRDAG 98 +RDR R D +RE+ RE D + + +T + Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIS 333 Query: 99 PRAGEHGVWEKPRQSRTRDGARG-LTWDAAAPPGPA---PWEAPEPPQ-PQRKGDPGRRR 153 RA + + K + R+++ G T DA GPA E PE P+ P RR Sbjct: 334 TRASK-SLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRI 392 Query: 154 PESEPPSERYLPSTPRPGREE-VEYYQSEAEG 184 P P S R P+ PR R++ +E Q + G Sbjct: 393 P--RPGSAR--PAPPRVKRQDSMEALQMDRSG 420 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%) Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64 +R +E D + ++ R H DR ++RS+ +R++ + R+ ++D+E Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202 Query: 65 RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111 + NR RE ERER ER DRG R RD+ R G EK R Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262 Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167 + R RD +G D G W+ + R+ D P ++ S S++ T Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320 Query: 168 PRPGREEVE 176 + + E E Sbjct: 321 FKDSKAETE 329 >gi|20070262 TNF receptor-associated factor 3 interacting protein 1 isoform 1 [Homo sapiens] Length = 691 Score = 58.2 bits (139), Expect = 1e-08 Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58 G E + R RD R ++ + +PR++ D + + + GNR R+G+R+ Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225 Query: 59 PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99 P+ ++++D GNR+R+RD E R+R+RERD D+G RD R Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282 Query: 100 RAGEHGVWEKPRQ 112 + GEH W+ R+ Sbjct: 283 KNGEHS-WDLDRE 294 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 1/98 (1%) Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65 G RE RA+ R R R R DR +R + RK + R DRD ERD+++ Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273 Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE 103 +RDR R + E + D ++ D +GE Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGE 311 Score = 46.2 bits (108), Expect = 5e-05 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 10/95 (10%) Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRP-RDRPGDPRRKRSSDGNRRRDGDRDPER-- 61 +G R RER R PD R DR R+R D RK+ ++ R+ +G ++ ER Sbjct: 207 NGGNRHREGERERAKARA-RPDNERQKDRGNRERDRDSERKKETE--RKSEGGKEKERLR 263 Query: 62 DQERDGNRDRNRDRERER----ERERDPDRGPRRD 92 D++R+ +RD+ +DR+R R E D DR R+ Sbjct: 264 DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%) Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64 +R +E D + ++ R H DR ++RS+ +R++ + R+ ++D+E Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202 Query: 65 RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111 + NR RE ERER ER DRG R RD+ R G EK R Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262 Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167 + R RD +G D G W+ + R+ D P ++ S S++ T Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320 Query: 168 PRPGREEVE 176 + + E E Sbjct: 321 FKDSKAETE 329 Score = 32.0 bits (71), Expect = 1.0 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 14/83 (16%) Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61 +D R R+++ R+ + + R RDR RD D+ +R Sbjct: 232 KDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE--------------RDRDKGKDR 277 Query: 62 DQERDGNRDRNRDRERERERERD 84 D+ R N + + D +RE+ RE D Sbjct: 278 DRRRVKNGEHSWDLDREKNREHD 300 >gi|125988409 RED protein [Homo sapiens] Length = 557 Score = 57.4 bits (137), Expect = 2e-08 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 11/150 (7%) Query: 6 GAREPRARPRER---DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 G R + + +++ + + P D D P + R + R R+ +RD ERD Sbjct: 292 GTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGL 122 ++RD R+R RDRERERER+R+ + +R ++ + P+ + + T++ + + Sbjct: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEK-PKVDDEPMDVDKGPGSTKELIKSI 410 Query: 123 TWDAAAPPGPAPWEAPE----PPQPQRKGD 148 A G A WE E P ++ GD Sbjct: 411 NEKFA---GSAGWEGTESLKKPEDKKQLGD 437 Score = 45.4 bits (106), Expect = 9e-05 Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 26/80 (32%) Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63 PS + PR + RER R+R D R RD DR ER++ Sbjct: 327 PSTTKTPRDKERER------------------------YRERERDRERDRDRDR--ERER 360 Query: 64 ERDGNRDRNRDRERERERER 83 ERD R+R RDRERE E++R Sbjct: 361 ERDRERERERDREREEEKKR 380 Score = 32.7 bits (73), Expect = 0.61 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%) Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69 PRA P P + H + R ++ D P RRK+ S + R + + ER+ + Sbjct: 43 PRAAPTSAPPSKSRHHEMPREYNEDED-PAARRRKKKSYYAKLRQQEIEREREL---AEK 98 Query: 70 DRNRDRERERERERDPDRGPRRDT---HRDAGPRA-GEHGVWEKPRQ 112 R+R +ER +D + T +R GP A + EK RQ Sbjct: 99 YRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145 >gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] Length = 520 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%) Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106 RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G Sbjct: 382 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 440 Query: 107 WEKPRQSRTRD 117 +E+ R SR ++ Sbjct: 441 YERHRASREKE 451 Score = 45.8 bits (107), Expect = 7e-05 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106 +R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E Sbjct: 386 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 445 Query: 107 WEKPRQSRTRD 117 + ++ R R+ Sbjct: 446 ASREKEERHRE 456 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78 D + D R D R+R D R RD DR+ ER +ER+ RD N D ER Sbjct: 372 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 431 Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R RE +RG R ++ R H E+ R +R +R Sbjct: 432 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 475 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54 AR + R RERD R ++ R DR R+R + R+R +SD R R Sbjct: 381 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 436 Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113 +R ER + +R+R+R R RE+E + R ++ R G+ H + + Sbjct: 437 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 495 Query: 114 RTRDGARGLTWDAAAPPGP 132 R+++G +A + P P Sbjct: 496 RSKEGK-----EAGSEPAP 509 >gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] Length = 588 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%) Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106 RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G Sbjct: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 508 Query: 107 WEKPRQSRTRD 117 +E+ R SR ++ Sbjct: 509 YERHRASREKE 519 Score = 45.8 bits (107), Expect = 7e-05 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106 +R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E Sbjct: 454 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 513 Query: 107 WEKPRQSRTRD 117 + ++ R R+ Sbjct: 514 ASREKEERHRE 524 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78 D + D R D R+R D R RD DR+ ER +ER+ RD N D ER Sbjct: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499 Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R RE +RG R ++ R H E+ R +R +R Sbjct: 500 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 543 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54 AR + R RERD R ++ R DR R+R + R+R +SD R R Sbjct: 449 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 504 Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113 +R ER + +R+R+R R RE+E + R ++ R G+ H + + Sbjct: 505 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563 Query: 114 RTRDGARGLTWDAAAPPGP 132 R+++G +A + P P Sbjct: 564 RSKEGK-----EAGSEPAP 577 >gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] Length = 594 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%) Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106 RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G Sbjct: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 514 Query: 107 WEKPRQSRTRD 117 +E+ R SR ++ Sbjct: 515 YERHRASREKE 525 Score = 45.8 bits (107), Expect = 7e-05 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106 +R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E Sbjct: 460 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 519 Query: 107 WEKPRQSRTRD 117 + ++ R R+ Sbjct: 520 ASREKEERHRE 530 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78 D + D R D R+R D R RD DR+ ER +ER+ RD N D ER Sbjct: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505 Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120 R RE +RG R ++ R H E+ R +R +R Sbjct: 506 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 549 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54 AR + R RERD R ++ R DR R+R + R+R +SD R R Sbjct: 455 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 510 Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113 +R ER + +R+R+R R RE+E + R ++ R G+ H + + Sbjct: 511 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569 Query: 114 RTRDGARGLTWDAAAPPGP 132 R+++G +A + P P Sbjct: 570 RSKEGK-----EAGSEPAP 583 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 4/87 (4%) Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR 71 A P + + R PD+ R DR R RKR +RRR G R R + + R+R Sbjct: 13 ASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERER 72 Query: 72 NRDRERERERERD---PDRGPRRDTHR 95 R +ERER++ERD DR +D HR Sbjct: 73 -RHKERERDKERDRNKKDRDRDKDGHR 98 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 13/118 (11%) Query: 3 DPSGAREPRARPR------ERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD 56 D S ++E R R R +RD R+ P + R R RDR R RS ++ + + Sbjct: 12 DASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE 71 Query: 57 RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114 R +++ERD RDRN+ ++R+R++D G RRD R + G K R+ R Sbjct: 72 RR-HKERERDKERDRNK---KDRDRDKD---GHRRDKDRKRSSLSPGRGKDFKSRKDR 122 Score = 48.1 bits (113), Expect = 1e-05 Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 30/203 (14%) Query: 2 EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-----RRRDG 55 E+ +R P R R R+RD P D+ R R R R G R RS + R ++ Sbjct: 18 EERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKER 77 Query: 56 DRDPERDQ---ERDGNRDRNRDRERERERER-DPDRGPRRDTHRDAGPR---AGEHGVWE 108 +RD ERD+ +RD ++D +R R+++R+R P RG + +D + EHG + Sbjct: 78 ERDKERDRNKKDRDRDKDGHR-RDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD-K 135 Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPP----QPQRKGDPGRRRPESEPPSERYL 164 KP+ A+ L+ + A EA P + +R+ + +RR + +R L Sbjct: 136 KPK-------AQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRML 188 Query: 165 PSTPRPGREEVEYYQSEAEGLLE 187 R++ + +Q +LE Sbjct: 189 EEE----RKKRKQFQDLGRKMLE 207 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 3/85 (3%) Query: 38 PGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRER--ERERERDPDRGPRRDTHR 95 P RKRS +R RD DRD + +D R R+RDR R R R R + R+ Sbjct: 15 PSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRH 74 Query: 96 DAGPRAGEHGVWEKPRQSRTRDGAR 120 R E +K R R +DG R Sbjct: 75 KERERDKERDRNKKDR-DRDKDGHR 98 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 40 DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGP 99 D + + +S R R P+R+++RD +R + ++R+R R RD RG R R Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66 Query: 100 RAGEHGVWEKPRQSRTRDGAR 120 A E+ + R RD R Sbjct: 67 SAER----ERRHKERERDKER 83 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74 R RD +R H R D R +RS R R+ +RD RD RD RDR RD Sbjct: 629 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 686 Query: 75 RERERER--ERDPDRGPR 90 RERERER +RD DRG R Sbjct: 687 RERERERLCDRDRDRGER 704 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62 A P+A P G P P + R D R D R D R+ + + RR R+ +R+ Sbjct: 609 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 666 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100 +ERD RD RDRER+R R+R+ +R D RD G R Sbjct: 667 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 704 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%) Query: 6 GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54 G +P P + P + HP H P + R KR D + R D Sbjct: 595 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 652 Query: 55 --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109 G R R+++R+ RDR RD R+RER+R DR R+ D GE G + + Sbjct: 653 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 709 >gi|10190682 chromobox homolog 8 [Homo sapiens] Length = 389 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 2/60 (3%) Query: 53 RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112 RD DRD +RD+ERD R+R R+RERERERER+ +RG R + + P KPR+ Sbjct: 148 RDRDRDRDRDRERD--RERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRK 205 Score = 42.4 bits (98), Expect = 8e-04 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 10/81 (12%) Query: 69 RDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAA 128 RDR+RDR+R+RER+R+ +R R+ R+ G V +KP D++ Sbjct: 148 RDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSS----------PGDSSK 197 Query: 129 PPGPAPWEAPEPPQPQRKGDP 149 GP P + P + G+P Sbjct: 198 KRGPKPRKELPDPSQRPLGEP 218 Score = 34.3 bits (77), Expect = 0.21 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 21/75 (28%) Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDP 85 D+ R D RD +RD ER++ER+ R+R R+RER R D Sbjct: 149 DRDRDRD--------------------RDRERDRERERERERERERERERERGTSRVDDK 188 Query: 86 DRGPRRDTHRDAGPR 100 P D+ + GP+ Sbjct: 189 PSSP-GDSSKKRGPK 202 Score = 33.5 bits (75), Expect = 0.36 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 11/84 (13%) Query: 76 ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDAAAPPGPAP 134 E R+R+RD DR RD R+ E+ R+ R R+ RG + P P Sbjct: 145 EAPRDRDRDRDRDRERDRERER----------ERERERERERERERGTSRVDDKPSSPGD 194 Query: 135 WEAPEPPQPQRKGDPGRRRPESEP 158 P+P+++ +RP EP Sbjct: 195 SSKKRGPKPRKELPDPSQRPLGEP 218 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74 R RD +R H R D R +RS R R+ +RD RD RD RDR RD Sbjct: 647 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704 Query: 75 RERERER--ERDPDRGPR 90 RERERER +RD DRG R Sbjct: 705 RERERERLCDRDRDRGER 722 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62 A P+A P G P P + R D R D R D R+ + + RR R+ +R+ Sbjct: 627 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 684 Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100 +ERD RD RDRER+R R+R+ +R D RD G R Sbjct: 685 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 722 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%) Query: 6 GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54 G +P P + P + HP H P + R KR D + R D Sbjct: 613 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 670 Query: 55 --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109 G R R+++R+ RDR RD R+RER+R DR R+ D GE G + + Sbjct: 671 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727 >gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapiens] Length = 437 Score = 52.8 bits (125), Expect = 6e-07 Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 21/164 (12%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPR---------DRPGDPRRKRSSDGNRRRDGDRD 58 R+ +R ER PG P P + R DR R D+ + RR RS D RR Sbjct: 213 RDDTSRYDER-PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK 271 Query: 59 PERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG 118 ER + R+ ++D++RDR+R R R+ RR+ R R G G +P ++ Sbjct: 272 EERRRSRERSKDKDRDRKRRSSRSRE---RARRERERKEELRGG-GGDMAEPSEAGDAPP 327 Query: 119 ARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162 G PPG + P+ P+ + + RR ER Sbjct: 328 DDG-------PPGELGPDGPDGPEEKGRDRDRERRRSHRSERER 364 Score = 49.3 bits (116), Expect = 6e-06 Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 48/151 (31%) Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-------------- 53 R R+R R R R ++ R+ +R +D+ D +R+ S R R Sbjct: 255 RRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGG 314 Query: 54 -----------------------DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR 90 DG PE ++ RD +R+R R ERER RD DR Sbjct: 315 DMAEPSEAGDAPPDDGPPGELGPDGPDGPE-EKGRDRDRERRRSHRSERERRRDRDRDRD 373 Query: 91 RDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121 RD G R E G RD ARG Sbjct: 374 RDREHKRGERGSERG----------RDEARG 394 Score = 48.9 bits (115), Expect = 8e-06 Identities = 41/130 (31%), Positives = 55/130 (42%), Gaps = 26/130 (20%) Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 D RE R R RERD R R R RDR R + + R R+ +D +RD Sbjct: 234 DRDRERERRERSRERDKERE------RRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRD 287 Query: 63 QERDGNRDRNRDRERERERERD------------------PDRGPRRDTHRDAGPRAGEH 104 ++R +R R R R RERER+ + PD GP + D GP E Sbjct: 288 RKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD-GPDGPEE 345 Query: 105 GVWEKPRQSR 114 ++ R+ R Sbjct: 346 KGRDRDRERR 355 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 6/98 (6%) Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPERDQER 65 AR R R E G + D P D P DG + DRD ER + Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSH 358 Query: 66 DGNRDRNRDRERERERERDPDRGPR-----RDTHRDAG 98 R+R RDR+R+R+R+R+ RG R RD R G Sbjct: 359 RSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGG 396 Score = 40.8 bits (94), Expect = 0.002 Identities = 54/171 (31%), Positives = 67/171 (39%), Gaps = 42/171 (24%) Query: 26 DQGRTHD--RPRDRPGD--PRRKRSSDGNRRRDGDRDPERDQERDGNRDR-NRDRERERE 80 ++GRT RPR G R+ +D N R G D R ER G +RDR+R+RE Sbjct: 179 ERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRE 238 Query: 81 -------RERDPDRGPRRDTHRDAGPRAGEHGVWE---------------KPRQSRTRDG 118 RERD +R RR RD R+ E K R SR+R+ Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRER 298 Query: 119 A----------RGLTWDAAAP--PGPAPWEAPEPPQPQRKGDPGRRRPESE 157 A RG D A P G AP P+ P G G PE + Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAP---PDDGPPGELGPDGPDGPEEK 346 Score = 35.8 bits (81), Expect = 0.072 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 27/85 (31%) Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63 P G P + R+RD RR R+H R+ RRRD DRD +RD+ Sbjct: 337 PDGPDGPEEKGRDRDRERR------RSHRSERE--------------RRRDRDRDRDRDR 376 Query: 64 ERDGNRDRNRDRERERERERDPDRG 88 E ++ ER ER RD RG Sbjct: 377 E-------HKRGERGSERGRDEARG 394 >gi|74272284 membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform c [Homo sapiens] Length = 1462 Score = 52.0 bits (123), Expect = 1e-06 Identities = 48/168 (28%), Positives = 66/168 (39%), Gaps = 32/168 (19%) Query: 3 DPSGAREPRARPRERDP--GRRPHPDQGRTHDRPRDRPGDPRR----KRSSDGN------ 50 DP G+RE +P E G PD G RP+DR + RR +R++ N Sbjct: 1265 DPKGSREYSRQPNEHHTWNGTSRKPDSGAC--RPKDRAPEGRRDAQAERAAAANGPKRRS 1322 Query: 51 --RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108 +RR+G R + ER ++ RD ER RER P R RD P + Sbjct: 1323 PEKRREGTRSADNTLERREKHEKRRDVSPERRRERSPTR------RRDGSPSRRRRSLER 1376 Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPES 156 Q R+ + R G +P + +R P RRR S Sbjct: 1377 LLEQRRSPERRR----------GGSPERRAKSTDRRRARSPERRRERS 1414 Score = 37.0 bits (84), Expect = 0.032 Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Query: 8 REPRARPRERD--PGRRPHPDQGRTHDR---PRDRPGDP-RRKRSSDGNRRRDGDRDPER 61 R R+ R RD P RR + R R R G P RR +S+D R R +R ER Sbjct: 1354 RRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRRARSPERRRER 1413 Query: 62 DQERDGNRDRNRDRERERER-ERDPDRGPRRDTHRDAGP 99 ++ DR RERE ++D R R + P Sbjct: 1414 SLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRP 1452 >gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] Length = 1220 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/103 (35%), Positives = 46/103 (44%), Gaps = 10/103 (9%) Query: 35 RDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTH 94 RDR +R RS D NR RD DR+ RD++ R R+R R R R RER+ + R Sbjct: 168 RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHK-RRHRSRSRSRSRTRERNKVKSRYRSRS 226 Query: 95 RDAGPRAGEHGVWEKPRQSRTRDGARGL-TWDAAAPPGPAPWE 136 R P K R+ R + G R L W P P E Sbjct: 227 RSQSP--------PKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261 Score = 45.8 bits (107), Expect = 7e-05 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Query: 51 RRRDGD-RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109 ++RD + RD + ++R +RDRNRDR+R+RER RD D R + + R E + Sbjct: 161 KQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKS 220 Query: 110 PRQSRTR 116 +SR+R Sbjct: 221 RYRSRSR 227 Score = 45.4 bits (106), Expect = 9e-05 Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 15/108 (13%) Query: 4 PSGAREPRARPRE-RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62 PS A + + R E RD R + R+ DR RDR D R R D ++RR R R Sbjct: 154 PSAAGQEKQRDAEHRD--RTKKKKRSRSRDRNRDRDRDRERNRDRD-HKRRHRSRSRSRS 210 Query: 63 QERDGNRDRNRDRERERERERDPDRGPR-----------RDTHRDAGP 99 + R+ N+ ++R R R R + DR R RD H D P Sbjct: 211 RTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPP 258 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 11 RARPRERDPGRRPHPDQGRTH-DRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ-ERDGN 68 R R R+RD R D R H R R R R + R R + P +D+ +RD Sbjct: 182 RNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY 241 Query: 69 RDRNRDRERERERERDPDRGP 89 +RN DR R++ +R P P Sbjct: 242 GERNLDRWRDKHVDRPPPEEP 262 Score = 38.1 bits (87), Expect = 0.015 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70 R R R+RD RR H + R+ R R+R R RS ++ DR +RD+ + N D Sbjct: 190 RERNRDRDHKRR-HRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRK-DRDKYGERNLD 247 Query: 71 RNRDRERERERERDPDRG 88 R RD+ +R +P G Sbjct: 248 RWRDKHVDRPPPEEPTIG 265 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.137 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,304,812 Number of Sequences: 37866 Number of extensions: 1258193 Number of successful extensions: 17749 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 291 Number of HSP's successfully gapped in prelim test: 705 Number of HSP's that attempted gapping in prelim test: 9524 Number of HSP's gapped (non-prelim): 4508 length of query: 410 length of database: 18,247,518 effective HSP length: 105 effective length of query: 305 effective length of database: 14,271,588 effective search space: 4352834340 effective search space used: 4352834340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.