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Search of human proteins with 65293358
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
(401 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens] 845 0.0
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] 525 e-149
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 77 4e-14
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 77 4e-14
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 74 2e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 72 7e-13
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 70 3e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 69 6e-12
gi|14670268 RD RNA-binding protein [Homo sapiens] 69 8e-12
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 67 3e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 63 5e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 63 5e-10
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 62 7e-10
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 61 2e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 59 1e-08
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 58 1e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 58 1e-08
gi|213385278 TNF receptor-associated factor 3 interacting protei... 58 1e-08
gi|20070262 TNF receptor-associated factor 3 interacting protein... 58 1e-08
gi|125988409 RED protein [Homo sapiens] 57 2e-08
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 55 1e-07
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 55 1e-07
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 55 1e-07
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 55 1e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 1e-07
gi|10190682 chromobox homolog 8 [Homo sapiens] 55 1e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 1e-07
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 53 6e-07
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 52 1e-06
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 51 2e-06
>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
Length = 401
Score = 845 bits (2183), Expect = 0.0
Identities = 401/401 (100%), Positives = 401/401 (100%)
Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE
Sbjct: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR
Sbjct: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS
Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
Query: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240
EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF
Sbjct: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240
Query: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300
GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP
Sbjct: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300
Query: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360
LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD
Sbjct: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360
Query: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF 401
IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF
Sbjct: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF 401
>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
Length = 410
Score = 525 bits (1351), Expect = e-149
Identities = 256/392 (65%), Positives = 290/392 (73%), Gaps = 3/392 (0%)
Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE
Sbjct: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR
Sbjct: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS
Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
Query: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240
EAEGLLECHKCKYLCTGR Q++EV+LN ++L C SY G++ S GG + +
Sbjct: 181 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY 240
Query: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300
YS F+G + E+ +QLD Q+ L+ P++ +A S L L + G
Sbjct: 241 ---YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSG 297
Query: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360
L+TE +L A GY + Y H + CK R+ LY KG + C G D
Sbjct: 298 KWLLTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTD 357
Query: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLK 392
A FA L ++++ VLA++ YR+ ++ K
Sbjct: 358 GAAATFACLLVIMYGASVVLALRSYREQKRYK 389
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 76.6 bits (187), Expect = 4e-14
Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
RE R R RER+ R ++ R +R RDR D ++R D +R RD DRD ER +R+
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127
+R R+R++ R+RERER+ +R R+ R+ E+ R+ R +D R
Sbjct: 380 DRSRSREKSRDRERERERERERERERERERERERERERERERERE-REKDKKRDRE---- 434
Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAE 183
E E +RK + R+ E E + L + R++ Y+ EAE
Sbjct: 435 --------EDEEDAYERRKLE--RKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480
Score = 64.7 bits (156), Expect = 1e-10
Identities = 30/96 (31%), Positives = 54/96 (56%)
Query: 1 MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
+E+ G +E + E++ R + R R+R + R+R + R R+ +RD +
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
RD+ ++ +RDR+R+R+R+R+RER DR R R+
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
Query: 17 RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG-DRDPERDQERDGNRDRNRDR 75
RD ++ ++G+ ++ R RR+R + R R+ +R+ ER++ER+ +++ R+R
Sbjct: 285 RDTHKKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERER 343
Query: 76 ERERERERD--PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
ERER+R+RD +R RD RD R E +SR+R+ +R
Sbjct: 344 ERERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSR 389
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 30/124 (24%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E S + R+R RE+ R ++ R +R R+R + R+R + R R+ ++D +R
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Query: 62 DQERDGN----------------------------RDRNRDRERERERERDPDRGPRRDT 93
D+E D R+R + RE E+E ER+ +R RR+
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER--RREM 489
Query: 94 HRDA 97
++A
Sbjct: 490 AKEA 493
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 27/117 (23%)
Query: 2 EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
+D S +RE R R RER+ R ++ R +R R+R + R+R + +++RD + D E
Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438
Query: 61 --------------------------RDQERDGNRDRNRDRERERERERDPDRGPRR 91
+ER R+ ++ ERE ER R+ + +R
Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 33.9 bits (76), Expect = 0.27
Identities = 46/214 (21%), Positives = 68/214 (31%), Gaps = 52/214 (24%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-------------------- 50
R R RER+ R ++ R +R R+R D +R R D
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458
Query: 51 ------------RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP--------- 89
+ R+ +++ ER++ER + R +E + D DR
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518
Query: 90 -------RRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQ 142
++ D R E E+ RQ +G D A EA Q
Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHP----DPDAELQRMEQEAERRRQ 574
Query: 143 PQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176
PQ K +P E E + P EE E
Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
Score = 31.6 bits (70), Expect = 1.3
Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 22/107 (20%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-----------------PGDPRRK 44
+DP R + R RD + D+ DR R++ P ++
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADE---RDRKREKEELEEIRQRLLAEGHPDPDAELQR 564
Query: 45 RSSDGNRRRDGD--RDPERDQERDGNRDRNRDRERERERERDPDRGP 89
+ RRR ++PE ++E + +++ RE E E +P++ P
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 76.6 bits (187), Expect = 4e-14
Identities = 55/167 (32%), Positives = 79/167 (47%), Gaps = 19/167 (11%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
R+ RAR R+R+ R R +R R+R D R++ + R R +R+ ER++ERD
Sbjct: 672 RDERARERDRERER------DRERERERERERDREREKERELERERAREREREREKERDR 725
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127
RDR+RD +RERERER+ DR R+ R+ R E + + R R+ AR +
Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785
Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREE 174
WE + KG RR E +R PR G +E
Sbjct: 786 R---QRDWEDKD------KGRDDRREKREEIREDR----NPRDGHDE 819
Score = 67.0 bits (162), Expect = 3e-11
Identities = 53/166 (31%), Positives = 76/166 (45%), Gaps = 35/166 (21%)
Query: 7 ARE-PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRS-SDGNRRRDGDRDPERDQE 64
ARE R R +ERD R D R +R R+R + R+R + R R+ +R+ ER++E
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771
Query: 65 RDGNRDRNRDRERERERE-------RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
R+ R R RD+ERER+R+ RD R R + D PR G R+S+ R
Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG-----HDERKSKKRY 826
Query: 118 GARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERY 163
G P+P ++P +RR E P S+ Y
Sbjct: 827 RNEG---------SPSPRQSP------------KRRREHSPDSDAY 851
Score = 66.2 bits (160), Expect = 5e-11
Identities = 38/113 (33%), Positives = 62/113 (54%), Gaps = 6/113 (5%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
R+ R R D ++ R DR R+R + R+R + +R R+ +R+ ER++ R+
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R+R ++R+RER+R+RD DR R+ RD R E E+ R+ R R+ R
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERD---REKER---EREREERERERER 762
Score = 56.6 bits (135), Expect = 4e-08
Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRD-RPGDPRRKRSSDGNRRRDG-------DRDP 59
R+ R + R+ RR H ++ R +R RD RP P R + + RD DR
Sbjct: 611 RDNRDQARDSSFERR-HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRDG 118
+R ER RDR R+R+RERERER+ +R R+ R+ RA E + + R RD
Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729
Query: 119 AR 120
R
Sbjct: 730 DR 731
Score = 55.1 bits (131), Expect = 1e-07
Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 10/118 (8%)
Query: 8 REPRARPRERDPGRRPHPDQG-RTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66
R+ R R GR ++ R +R DR D R +R+ + +R R+ DR+ ER++ER+
Sbjct: 637 RDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERE 696
Query: 67 GNRDRNRDRE----RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
+R+R ++RE R RERER +R RD RD R +H + + R R+ R
Sbjct: 697 RDREREKERELERERARERER--EREKERDRERD---RDRDHDRERERERERDREKER 749
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 5 SGAREPRARPRERDP---GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
SG+ + R R +ERD R ++ T R DR D R+ D +R R+ +R+ ER
Sbjct: 1290 SGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERER 1349
Query: 62 DQERDGNRDRNR------DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
D+ RD +R+R R +R+R+R+R+R + R GEH E+ +S +
Sbjct: 1350 DKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEH---ERDLESTS 1406
Query: 116 RD 117
RD
Sbjct: 1407 RD 1408
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPR----DR-PGDPRRKRSSDGNRRRDGDR 57
D +R +R + R+ H G R R DR D R+R R+R+ DR
Sbjct: 1266 DRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDR 1325
Query: 58 DPERDQERDGNRDRNRDRERERERE--RDPDRGPRR 91
D ++D R+ +RDR R+RERERER+ RD DR R
Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1361
Score = 49.7 bits (117), Expect = 5e-06
Identities = 40/119 (33%), Positives = 56/119 (47%), Gaps = 15/119 (12%)
Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
PR R R+ GR H ++HDR +R D R KR +R +D + E +Q++ +R
Sbjct: 389 PRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR----DREKDSREEREYEQDQSSSR 444
Query: 70 DRNRDRE----RERERERDP-DRGPRRDTH-----RDAGPRAGEHGVWEKPRQSR-TRD 117
D DRE R+R RD DR RD+ R+ + + PR SR TRD
Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRD 503
Score = 43.5 bits (101), Expect = 3e-04
Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 21/116 (18%)
Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
D RE RER +R R+R + R+R + R RD +R+ +RD
Sbjct: 744 DREKEREREREERER--------------ERERERERERERERERERARERDKERERQRD 789
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTH--RDAGPRAGEHGVWEKPRQSRTR 116
E ++D+ RD RE+ E DR P RD H R + R G PRQS R
Sbjct: 790 WE---DKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGS-PSPRQSPKR 840
Score = 42.7 bits (99), Expect = 6e-04
Identities = 45/191 (23%), Positives = 77/191 (40%), Gaps = 19/191 (9%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R RER+ R ++ R D+ R+R D K +RR + E RDG+ +
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819
Query: 71 RNRDRERERERERDPDRGPRR--------DTHRDAGPRAGEHGVWE---KPRQSRTRDGA 119
R + E P + P+R D + + +H + +P++SR+ +
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 120 RGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQ 179
LT D W+ E +P+RK + RR E E + R E +E +
Sbjct: 880 H-LTEDR-----QGRWK-EEDRKPERK-ESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Query: 180 SEAEGLLECHK 190
A+ ++ H+
Sbjct: 932 MRAQDIIGHHQ 942
Score = 36.6 bits (83), Expect = 0.041
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 15/109 (13%)
Query: 57 RDPERDQERDGNRDRNRDRERERERERDP--------DRGPRRDTHRDAGPRAG----EH 104
+D ++ RDG +DR RD ER+RE+ P P H + ++G H
Sbjct: 287 KDRIEEKTRDG-KDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRH 345
Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR 153
PR+ RT + T +P+ + PQRK P R R
Sbjct: 346 S--PSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Score = 35.8 bits (81), Expect = 0.071
Identities = 45/168 (26%), Positives = 65/168 (38%), Gaps = 24/168 (14%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPE 60
ED G R+ RE R DQ + D DR P D R +R + R R RD
Sbjct: 418 EDTRGKRDREKDSREE---REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSR 474
Query: 61 --------RDQERDGNRDRN-------RDRERERERE-RDPDRGPRRDTHRDAGPRAGEH 104
RD RD R+ RD R+RE RD R + DT+ + G +
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHR--KEDTYPEESRSYGRN 532
Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPP--GPAPWEAPEPPQPQRKGDPG 150
+ E+ ++ R+ +R + G + PE P+ +G G
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRG 580
Score = 33.5 bits (75), Expect = 0.35
Identities = 40/150 (26%), Positives = 49/150 (32%), Gaps = 57/150 (38%)
Query: 8 REPRARPRERDPG--------------------------------RRPHPDQGRTHDRPR 35
RE R +PR P R P P RT P
Sbjct: 308 REKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPL 367
Query: 36 DRP---------GDPRRKRSSDGNR---RRDG-----------DRDPERDQERDGNRDRN 72
R P+RK+S +R R G DR ER ++ G RDR
Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427
Query: 73 RDRERERERERDPDRGPRRDTHRDAGPRAG 102
+D ERE E+ D+ RD D PR G
Sbjct: 428 KDSREEREYEQ--DQSSSRDHRDDREPRDG 455
Score = 33.1 bits (74), Expect = 0.46
Identities = 33/99 (33%), Positives = 46/99 (46%), Gaps = 15/99 (15%)
Query: 39 GDPRRKRSSDGNRRRDGDR---DPERDQE---RDGNRD-RNRDRER-----ERERERDPD 86
G+P R SSD R PE D++ R G+ D R+R +ER +RERER+
Sbjct: 1257 GEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERR 1316
Query: 87 RGPRRDTHRDAG---PRAGEHGVWEKPRQSRTRDGARGL 122
+R+ RDA PR + + + R RD R L
Sbjct: 1317 DTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDL 1355
Score = 29.6 bits (65), Expect = 5.1
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 33 RPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRD 92
R +RP R+R N+R+D D +P++ + + ++ R R RE++ + +
Sbjct: 76 RSPERPTGDLRERMK--NKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER 133
Query: 93 THRDAGPRAGEHGV-WEKPR 111
T P + E V WE R
Sbjct: 134 T-----PESEEENVEWETNR 148
Score = 29.6 bits (65), Expect = 5.1
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 40 DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR-DRERERERERD 84
D RSS R R +RD RDQ RD + +R +R+R RERD
Sbjct: 594 DSWETRSSYPERDRYPERD-NRDQARDSSFERRHGERDRRDNRERD 638
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 74.3 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 8/153 (5%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
+ R RERD GR D+ R +R R D +R ++ R RD +R+ ++++E + +RD
Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190
Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKP-RQSRTRDGARGLTWDAAAP 129
R RD E+ERER+ D +R +R T + G E R+ R RD RG D
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER- 249
Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
+ E + +RK + + R E + +R
Sbjct: 250 ------DRKEERKKERKKERKKERKEKKKEEKR 276
Score = 63.5 bits (153), Expect = 3e-10
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 11/132 (8%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNR---------- 51
+D G RE RERD R ++ DR R R + R+R +D R
Sbjct: 159 KDRDGQRETETE-RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217
Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111
+R+ DR+ ER+ +R R R+RDR +ER+RERD +++ ++ E EK R
Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
Query: 112 QSRTRDGARGLT 123
+ + R G++
Sbjct: 278 EDKKRKWGEGIS 289
Score = 60.8 bits (146), Expect = 2e-09
Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 5/121 (4%)
Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
D R+ R +E++ R ++ +R R+R R+R D R R+ DRD E++
Sbjct: 93 DRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKE 152
Query: 63 QERDGNRDRN--RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGA 119
+ER +DR+ R+ E ERER+R+ ++ R+T RD + E+ RQ+ R RD
Sbjct: 153 RERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK--ERERQTDRERDRQ 210
Query: 120 R 120
R
Sbjct: 211 R 211
Score = 56.6 bits (135), Expect = 4e-08
Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 12/88 (13%)
Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG--------DRDPERDQE 64
R RERD R ++ R DR RDR RR++ + NR RD DR+ E+ +
Sbjct: 77 RQRERDRVREK-TEKERDRDRKRDRE---RRRKEKETNRNRDREKQTEIERDREREKQKG 132
Query: 65 RDGNRDRNRDRERERERERDPDRGPRRD 92
R+ RDR R+RER+R+RE++ +R +D
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKD 160
Score = 52.4 bits (124), Expect = 7e-07
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 14 PRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR 73
PR G+ G R RDR + + ++ D +R+RD +R R +E++ NR+R+R
Sbjct: 60 PRSWGLGQAHKDADGDDRQRERDRVRE-KTEKERDRDRKRDRER---RRKEKETNRNRDR 115
Query: 74 DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT---RDGAR 120
+++ E ER+R+ ++ R+ RD G EK R+ +T RDG R
Sbjct: 116 EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 72.4 bits (176), Expect = 7e-13
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 7/167 (4%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R RER+ ++ R DR RDR R+R R R +R+ ERD+ER+ RD
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 71 RNRDRE-RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129
R+RDR+ R++ERER DR +R T RD E + ++ R R+ R +
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDR-----ETERKRERQRERERERERNRKRERERE 322
Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176
E + + K +R+ ++E ER T R GR + E
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERN-RQTGREGRRQAE 368
Score = 68.6 bits (166), Expect = 1e-11
Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 34/189 (17%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R RER+ R+ ++ +R RDR D +++R + RDG R+ E+ +ER+ +R+
Sbjct: 369 RERERERERDRQSARER---EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 71 --RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG---------A 119
R R+R RERE+++ +R R T R AG + ++ P R G
Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485
Query: 120 RGLTW-----DAAAPPGPAPWEAP--------------EPPQPQRKGDPGR-RRPESEPP 159
RG+ W D A PW P EP +++G G RRP
Sbjct: 486 RGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFG 545
Query: 160 SERYLPSTP 168
+E L P
Sbjct: 546 TENPLSQAP 554
Score = 66.6 bits (161), Expect = 4e-11
Identities = 39/114 (34%), Positives = 65/114 (57%), Gaps = 5/114 (4%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
R + R R+ D R+ ++ R +R R+R + R+R + R R+ +R+ ER+++R+
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGAR 120
RDR ++RER+R+R+ + DR R T R+ G R E E+ R+ R R AR
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGRE-GRRQAER---ERERERERDRQSAR 383
Score = 64.7 bits (156), Expect = 1e-10
Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 9/117 (7%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER-- 65
R + R R+RD R D+ + +R DR D R+R + NR+++ +R+ ER+ ER
Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERD--RQREKERNRQKERERETEREGERGR 139
Query: 66 ----DGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRD 117
DG R+R R R+ E+ERER DR +R T R+ R E E+ + R R+
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
Score = 63.2 bits (152), Expect = 4e-10
Identities = 33/116 (28%), Positives = 59/116 (50%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E + + R R ++R R H ++ R ++ R+R D R R + R R +R+ E
Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131
Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
++E + RDR D +RERER+RD ++ R T R+ + + E+ R+ ++
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
+D G R R +ER+ R + T DR R+R + R R D +R R DR+ ER
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERET-DRKRERRREKDRHRKRDRHRERQRDREKER 105
Query: 62 ----DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
D+ERD R++ R+R++ERERE + + RD D EK R+ +T
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Score = 61.2 bits (147), Expect = 2e-09
Identities = 27/107 (25%), Positives = 60/107 (56%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R RE++ R+ ++ R ++ R+R + R+ +G R RD D +R++ER + +
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
+ R+R+ +RER+R +R +++ R+ + ++ ++++T D
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 12/119 (10%)
Query: 2 EDPSGAREPRARPRERDPGRRP---HPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD 58
E +E R R R+R+ + H ++GR +R R+ + RKR +D R RD R
Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD--RERDRQRK 237
Query: 59 PERDQERDGNRDR--NRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
ER++E+ R+R R+ ER++ERER+ DR RD + R ++ RQ RT
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ-----TDRKRQRRT 291
Score = 60.8 bits (146), Expect = 2e-09
Identities = 34/113 (30%), Positives = 54/113 (47%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
+ R R RER+ R ++ R +R R+R + R R + R+R + +R++ R
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R+ R ERERERER+ DR R+ R + + + + RDG R
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R RERD R ++ + +R +R G+ R R +DG R R+ RD E+++ER D
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ--TD 164
Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R R R+ ER R+++ +R R R+ + + E R R+ R
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Score = 58.5 bits (140), Expect = 1e-08
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
RE R RE D R ++ R R RDR + +R R + R+ D +RD +R++ER+
Sbjct: 66 REKRQTERETDRKRERRREKDR--HRKRDRHRERQRDREKERERQTDRERDRQREKERNR 123
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
++R R+ ERE ER RD +R+ R ++ RQ +T
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Score = 58.5 bits (140), Expect = 1e-08
Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 12/115 (10%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R RE + GR D R +R RD + R+R +D R+R +R+ ++++ER+ NR
Sbjct: 129 RETEREGERGRDRQTDGQRERERQRD--AEKERERQTDRERQRQTERNRQKEREREKNRQ 186
Query: 71 RNRDRERERERE-----RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R+RER+RE+E R +RG R+ R+ E K + R RD R
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERET-----ETETERKRQTDRERDRQR 236
Score = 56.6 bits (135), Expect = 4e-08
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 8/182 (4%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E + + R R+R+ R+ + R +R R+R + R+R + R+R+ +RD E+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
++ER R DRER R+ R+ R R+ R+ E+ + R RD R
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERER--ERDRQSAREREERERDRDRDRQ 397
Query: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSE 181
+ + + QR+ + R ESE ER + GRE Q++
Sbjct: 398 KERERQTEKDR---DGQRETEKQREREKDR---ESERGRERGREREKQKGRERDRERQTD 451
Query: 182 AE 183
+
Sbjct: 452 RQ 453
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 17 RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRE 76
R PG + P + +D GD R + RR R ER+ +R R R +DR
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 77 RE----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT-RDGARG 121
R+ RER+RD ++ R T R+ + + +K R+ T R+G RG
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 13/75 (17%)
Query: 32 DRPRDRPGD---PRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDR-------ERERER 81
D R RPG PRR+ ++ DGD +R++ R R+R R++ +R+RER
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRER 81
Query: 82 ERDPDRGPRRDTHRD 96
R+ DR +RD HR+
Sbjct: 82 RREKDRHRKRDRHRE 96
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 70.5 bits (171), Expect = 3e-12
Identities = 52/127 (40%), Positives = 70/127 (55%), Gaps = 11/127 (8%)
Query: 1 MEDPSG-AREPRARPRERDPGRRPHPDQGRTHDRPR--DRPGDPRRKRSSDGNRRRDGDR 57
+E+P R R RER+ GR + + R DRPR DR D R D NR R +R
Sbjct: 2100 LEEPDAQGRASEDRRRERERGR--NWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANR 2157
Query: 58 DPERDQER----DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS 113
D ER+ +R D +R+R+R+RERER+R RD DR R+ RD R E G K R S
Sbjct: 2158 DREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKA-RDRERGRDRKDR-S 2215
Query: 114 RTRDGAR 120
++++ AR
Sbjct: 2216 KSKESAR 2222
Score = 67.4 bits (163), Expect = 2e-11
Identities = 44/107 (41%), Positives = 56/107 (52%), Gaps = 6/107 (5%)
Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
RPRE D R D R DR R+R + R+R +D R ++ DR ER + R+ RDR
Sbjct: 2131 RPREWD--RHRDKDSSRDWDRNRERSANRDREREAD--RGKEWDRSRERSRNRERERDRR 2186
Query: 73 RDRERERERERDPDRGPRRDTHRDAGPR--AGEHGVWEKPRQSRTRD 117
RDR+R R RERD D+ R+ RD R + E KP SR D
Sbjct: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/91 (40%), Positives = 48/91 (52%), Gaps = 9/91 (9%)
Query: 13 RPRER---DPGRRP--HPD-QGR-THDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
R RER P +P PD QGR + DR R+R R D +R R+ DR ++D R
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRD 96
D +R+R R R+RERE DRG D R+
Sbjct: 2146 DWDRNRERSANRDRERE--ADRGKEWDRSRE 2174
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 9/116 (7%)
Query: 19 PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP------ERDQERDGNRDRN 72
PG+ P D R+ G R ++ +G +R D P E D + + DR
Sbjct: 2055 PGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRR 2114
Query: 73 RDRERERE--RERDPDRGPRRDTHRDA-GPRAGEHGVWEKPRQSRTRDGARGLTWD 125
R+RER R RERD DR D HRD R + + R R+ RG WD
Sbjct: 2115 RERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWD 2170
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 69.3 bits (168), Expect = 6e-12
Identities = 34/86 (39%), Positives = 52/86 (60%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R R+R+ R+ ++ + DR R R D R+R+ G R RD + ERD+ER+ R
Sbjct: 80 RERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQ 139
Query: 71 RNRDRERERERERDPDRGPRRDTHRD 96
R R+R+R+RER+R+ DR +R R+
Sbjct: 140 RERERQRQRERKRETDRERQRWAERE 165
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/84 (41%), Positives = 50/84 (59%)
Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
R ER R+ ++ R DR RD+ D RKR +D NR R+ ERD++ + RDR
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
Query: 73 RDRERERERERDPDRGPRRDTHRD 96
R+R+R+RERER R +R+T R+
Sbjct: 134 RERQRQRERERQRQRERKRETDRE 157
Score = 65.1 bits (157), Expect = 1e-10
Identities = 38/88 (43%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R +ERD R+ + R +R R+R RKR +D R RD DRD ER +E D NR+
Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTD--RERDKDRDRERKRETDRNRE 113
Query: 71 RNRD--RERERERERDPDRGPRRDTHRD 96
RNR RER+++ ER+ DR R R+
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRE 141
Score = 64.7 bits (156), Expect = 1e-10
Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
RE R R R+R R D+ + +R ++R +R+R ++ R +R +R+++R
Sbjct: 33 RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDA 126
+R+R++DR+RER+RE D +R R R+ + E+ RQ R R+ R
Sbjct: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKR 152
Query: 127 AAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
W E + +RK + + R E + +R
Sbjct: 153 ETDRERQRWAEREERKKERKKERKKERKEKKKEEKR 188
Score = 59.7 bits (143), Expect = 5e-09
Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 2 EDPSGAREPRARPRERD-------PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD 54
E G R R R+R+ R D+ R DR DR + R++ D R+R+
Sbjct: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69
Query: 55 GD--RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
+ R+ ER +ER R+R R +RER+++RD +R D +R+ + G E+ +Q
Sbjct: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR----ERDKQ 125
Query: 113 S-RTRDGAR 120
+ R RD R
Sbjct: 126 TERERDRER 134
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Query: 16 ERDPGRRPHPDQGRTHDRPRDRPGD-----PRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
ER R+ D+G+ +R RDR + R R +R R+ DR +R++ER+ ++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 71 RNRDRERERERERDPDRGPRRDTHRD 96
R+R R+RERE ER+ +R R R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRE 87
Score = 57.8 bits (138), Expect = 2e-08
Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRP-------RDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
R R RE D G+ ++ R +R R R D R+R +R ++ +R ERD+
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 64 ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
+R R+ R+ ER+RER+R +R + D RD R E + R R G R
Sbjct: 65 QRQRERETERETERQRERQRQRERKRQTDRERDK-DRDRERKRETDRNRERNRKGGR 120
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 18/97 (18%)
Query: 42 RRKRSSDGNRRRDGDRDPERDQERDG-----NRDRNRDR------------ERERERERD 84
+R+R + +R ++ +R+ +R +ER+ NR R RDR ERER++ERD
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 85 PDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGAR 120
R R+T R+ + E+ RQ+ R RD R
Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDR 100
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
G + RERD R R R R+R RKR +D R+R +R+ ER +ER
Sbjct: 119 GRERDKQTERERDRERE------RQRQRERERQRQRERKRETDRERQRWAERE-ERKKER 171
Query: 66 DGNRDRNRDRERERERERD 84
R + R +++ E+ R+
Sbjct: 172 KKERKKERKEKKKEEKRRE 190
>gi|14670268 RD RNA-binding protein [Homo sapiens]
Length = 380
Score = 68.9 bits (167), Expect = 8e-12
Identities = 47/107 (43%), Positives = 58/107 (54%), Gaps = 19/107 (17%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E+ SGA + PR R + R+H+R RDR D R R RD DRD ER
Sbjct: 171 EERSGAHSSASPPRSRS--------RDRSHERNRDRDRDRERDRD------RDRDRDRER 216
Query: 62 DQERDGNRDRNRDRERERERERDPDR---GPRRDTHRDAGPRAGEHG 105
D++RD RDR+RDRER+R+RERD DR GP R + RA G
Sbjct: 217 DRDRD--RDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261
Score = 66.6 bits (161), Expect = 4e-11
Identities = 35/91 (38%), Positives = 51/91 (56%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E+ G PR D G + PR R D +R+ D +R R+ DRD +R
Sbjct: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210
Query: 62 DQERDGNRDRNRDRERERERERDPDRGPRRD 92
D++R+ +RDR+RDR+R+RER+RD +R RD
Sbjct: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/72 (37%), Positives = 37/72 (51%)
Query: 25 PDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERD 84
P G R D + R S + R RD ++ RD +RDR RDR+R+R+R+R+
Sbjct: 156 PGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRE 215
Query: 85 PDRGPRRDTHRD 96
DR RD RD
Sbjct: 216 RDRDRDRDRDRD 227
Score = 45.4 bits (106), Expect = 9e-05
Identities = 26/84 (30%), Positives = 39/84 (46%)
Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
R RE P G PR + + + R +R ER+ +RDR+
Sbjct: 142 RLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD 201
Query: 73 RDRERERERERDPDRGPRRDTHRD 96
R+R+R+R+R+RD +R RD RD
Sbjct: 202 RERDRDRDRDRDRERDRDRDRDRD 225
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 67.0 bits (162), Expect = 3e-11
Identities = 49/157 (31%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 11 RARPRERDPGR-RPHPDQGRTHDR--PRDRPGDPRRKRSSDGNRRRDG--DRDPERDQER 65
R R R R+ R R + +T DR RDR D R R D +R R+ DR+ ER +ER
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWD 125
+ +RDR R+ ERER++ER+ DR D R V ++ R+ + G T
Sbjct: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT-- 136
Query: 126 AAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
+ Q +R+ + GR R + ER
Sbjct: 137 ------DRETDRERERQAERERETGRERKTEDRHRER 167
Score = 60.5 bits (145), Expect = 3e-09
Identities = 35/107 (32%), Positives = 52/107 (48%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R RERD R+ ++ R +R DR + R+R R + RD ER+++++ R+
Sbjct: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133
Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
R DRE +RERER +R R R E K + R R+
Sbjct: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Score = 55.5 bits (132), Expect = 9e-08
Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 14/107 (13%)
Query: 20 GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--NRDRNRDRER 77
GR H + T DR R+R + R+R + + DR ERD++RD NR+R+RDRER
Sbjct: 7 GRHTHTET-ETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDRER 64
Query: 78 E----------RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114
E RERERD DR + RD H ++ RQ +
Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111
Score = 54.3 bits (129), Expect = 2e-07
Identities = 27/89 (30%), Positives = 45/89 (50%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
R ++ +R R D+ R +R RDR + + R + R R+ DRD +R+ ER+
Sbjct: 33 RAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERER 92
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRD 96
+++R DR E +RER + + RD
Sbjct: 93 DKERETDRHTETDRERQKQKEREMERVRD 121
Score = 53.9 bits (128), Expect = 3e-07
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66
A+E + R + R+ ++ R DR R+R R+ R RD DR E ++ERD
Sbjct: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD 93
Query: 67 GNRDRNR----DRERERERERDPDRGPRRDTHRDAGPRAG 102
R+ +R DRER++++ER+ +R RD R+ G
Sbjct: 94 KERETDRHTETDRERQKQKEREMER--VRDREREKQKEMG 131
Score = 53.5 bits (127), Expect = 3e-07
Identities = 31/92 (33%), Positives = 54/92 (58%), Gaps = 8/92 (8%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRR-----KRSSDGNRRRDGDRDPERDQER 65
R R ++++ GR D R DR R+R + R +++ D +R R+ +R ER+++R
Sbjct: 122 REREKQKEMGRERQTD--RETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
Query: 66 DGN-RDRNRDRERERERERDPDRGPRRDTHRD 96
+ R+R+ D ERER+RE D R +R++ R+
Sbjct: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 24/132 (18%)
Query: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGN---- 68
R R+RD R D+ R ++ DR G+ +R+R D +R+R+ +R+ ++++E D +
Sbjct: 46 RDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105
Query: 69 --------------RDRNRD------RERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
RDR R+ RER+ +RE D +R + + R+ G
Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165
Query: 109 KPRQSRTRDGAR 120
+ + R R+ R
Sbjct: 166 ERERERKRERER 177
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 10/76 (13%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR- 69
R RER+ GR + +T DR R+R + +R+R +R +R+ D ER+ R
Sbjct: 146 RQAERERETGR-----ERKTEDRHRERERERKRERE---RKRETKERERHTDMERERQRE 197
Query: 70 -DRNRDRERERERERD 84
DR RDR+RE ERERD
Sbjct: 198 TDRKRDRQRESERERD 213
Score = 36.6 bits (83), Expect = 0.041
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 10/83 (12%)
Query: 47 SDGNRRRDGDRDPERDQERDGNRDRNRDRER---------ERERERDPDRGPRRDTHRDA 97
++G +R +ER DR RDR + ER+R+RD +R RD R+
Sbjct: 5 TEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64
Query: 98 GPRAGEHGVWEKPRQSRTRDGAR 120
+ G ++ R+ R RD R
Sbjct: 65 EKQTDREGERQRERE-RDRDRQR 86
Score = 30.8 bits (68), Expect = 2.3
Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 26/151 (17%)
Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERD---PDRGPRRDTHRDAGPRAGEHGVWE 108
+ +G + D R+R R+ +RER+R ++ DR RD RD E
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR-PESEPPSERYLPST 167
+ +Q+ R+G R Q +R+ D R+R E E ER
Sbjct: 64 REKQT-DREGER---------------------QRERERDRDRQRETERERDKERETDRH 101
Query: 168 PRPGREEVEYYQSEAEGLLECHKCKYLCTGR 198
RE + + E E + + + K GR
Sbjct: 102 TETDRERQKQKEREMERVRDREREKQKEMGR 132
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 62.8 bits (151), Expect = 5e-10
Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R + RER+ R ++G+ DR ++R D + + D R R+ + + +RD+E++ +D
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454
Query: 71 RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123
+ ++RE++R +E D R P R + R+ + +S +R T
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514
Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176
+ P+P + + + K D R E E + S R G+E++E
Sbjct: 515 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568
Score = 57.8 bits (138), Expect = 2e-08
Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 8 REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
R+ R+R RD + ++ + DR ++R + R++ + + +D D++ E+D
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
+E+D +DR R+RE+E E++RD ++ +D ++
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458
Score = 57.4 bits (137), Expect = 2e-08
Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
S +R+ R RE+ + ++ R +R R++ + ++R + +R ++ ++D E+D+E
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430
Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
+D R+R ++ E++R++E++ ++ ++ +D E +K ++SRT
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 479
Score = 55.8 bits (133), Expect = 7e-08
Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%)
Query: 11 RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57
R+R ++R + PH + ++ +R RD+ D R K R + +R ++ +R
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401
Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
+ ER++E++ ++++RD+ERE++RE+D ++ R+ ++
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 5 SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60
S A EP + + ER GR R+H R + R RRKRS +R R +R
Sbjct: 290 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 343
Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118
R ++R ++ ++ R + RER + R RD +D + E V EK R+ R R+
Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403
Query: 119 AR 120
R
Sbjct: 404 ER 405
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 5 SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59
S +R PR R R P R + + ++ RD + R + S R+ DRD
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563
Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106
+ E +N +E+E ++PD ++ PR E+ +
Sbjct: 564 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 62.8 bits (151), Expect = 5e-10
Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R + RER+ R ++G+ DR ++R D + + D R R+ + + +RD+E++ +D
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338
Query: 71 RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123
+ ++RE++R +E D R P R + R+ + +S +R T
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398
Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176
+ P+P + + + K D R E E + S R G+E++E
Sbjct: 399 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452
Score = 57.8 bits (138), Expect = 2e-08
Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 8 REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
R+ R+R RD + ++ + DR ++R + R++ + + +D D++ E+D
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
+E+D +DR R+RE+E E++RD ++ +D ++
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342
Score = 57.4 bits (137), Expect = 2e-08
Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
S +R+ R RE+ + ++ R +R R++ + ++R + +R ++ ++D E+D+E
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314
Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
+D R+R ++ E++R++E++ ++ ++ +D E +K ++SRT
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 363
Score = 55.8 bits (133), Expect = 7e-08
Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%)
Query: 11 RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57
R+R ++R + PH + ++ +R RD+ D R K R + +R ++ +R
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285
Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
+ ER++E++ ++++RD+ERE++RE+D ++ R+ ++
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 5 SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60
S A EP + + ER GR R+H R + R RRKRS +R R +R
Sbjct: 174 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 227
Query: 61 RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118
R ++R ++ ++ R + RER + R RD +D + E V EK R+ R R+
Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287
Query: 119 AR 120
R
Sbjct: 288 ER 289
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 5 SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59
S +R PR R R P R + + ++ RD + R + S R+ DRD
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447
Query: 60 ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106
+ E +N +E+E ++PD ++ PR E+ +
Sbjct: 448 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 62.4 bits (150), Expect = 7e-10
Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 15/121 (12%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQERDGN 68
R R R+R R D+ DR R R D R+R D +R+R+ GDRD E + ER
Sbjct: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125
Query: 69 RDRNRDRERERERER--------DPDRGPRRDTHRDAGPRAGEHGVW-----EKPRQSRT 115
R+R RDR+RE++RER D DR + RD GE + E+ +Q T
Sbjct: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
Query: 116 R 116
R
Sbjct: 186 R 186
Score = 59.3 bits (142), Expect = 6e-09
Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
P+ RE R R RER+ R+ ++ R DR ++ D +RKR + R RD DR ER
Sbjct: 54 PAIIRE-RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
Query: 64 ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG 98
+RD + R ERER+R+R ++ R R+ G
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIG 147
Score = 58.5 bits (140), Expect = 1e-08
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
+ + R RE+D D+ R DR R R D RKR G+R R+ + + + ++ER
Sbjct: 71 KRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQR 130
Query: 68 NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111
+R R +DRER+R+RE D+ +T +D R E G E+ R
Sbjct: 131 DRKREKDRERQRQREIGIDKDREIETEKDR-DREREMGETERYR 173
Score = 55.5 bits (132), Expect = 9e-08
Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
+D RE R RD R + DR R+R R K + +R R +R+ +R
Sbjct: 158 KDRDREREMGETERYRDRERERQKQRETRRDRDRERQ---REKEDRERDRDRQKEREKDR 214
Query: 62 DQERDGNRDRNRDRERERERERDPDR 87
+ER+ RDR+++R+RER+RE+D DR
Sbjct: 215 YRERETGRDRDKERDRERQREKDRDR 240
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/108 (27%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD-GNRDRNR 73
R+R+ ++ R DR R++ + +R+R ++ R+ + + +RD+ER+ G +R R
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 74 DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
DRERER+++R+ R R+ R+ R + ++ + R R+ G
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
Score = 52.8 bits (125), Expect = 6e-07
Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 13 RPRERDPGRRP-HPDQGRTHDRPRDRPGDPRRKRSSDG-NRRRDGDRDPERDQERDGNRD 70
R RER+ G + D+ R + R+ D R+R + +R RD DR ER+++R R+
Sbjct: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
Query: 71 RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
RDR++ER+RER ++ R D P G WE
Sbjct: 220 TGRDRDKERDRERQREKDRDRQKAIDCVP-----GRWE 252
Score = 51.6 bits (122), Expect = 1e-06
Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 15/139 (10%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSS-------DGNRRRDGDRDPERDQ 63
R R RE+D R+ + G DR + D R+R D R R R+ RD+
Sbjct: 130 RDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDR 189
Query: 64 ERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
+R+ R DR RDR+R++ERE+ DR R+T RD EK R +
Sbjct: 190 DRERQREKEDRERDRDRQKEREK--DRYRERETGRDRDKERDRERQREKDRDRQKAIDCV 247
Query: 121 GLTWDA---AAPPGPAPWE 136
W+ A P WE
Sbjct: 248 PGRWEVTVMAVDCVPGRWE 266
Score = 32.3 bits (72), Expect = 0.78
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 26/80 (32%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
+E R R R+R +++R D R R+ RD RD+ERD
Sbjct: 197 KEDRERDRDR------------------------QKEREKDRYRERETGRD--RDKERDR 230
Query: 68 NRDRNRDRERERERERDPDR 87
R R +DR+R++ + P R
Sbjct: 231 ERQREKDRDRQKAIDCVPGR 250
Score = 30.0 bits (66), Expect = 3.9
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
D R+ RERD R+ R DR R+R R + D R+R+ DRD ++
Sbjct: 188 DRDRERQREKEDRERDRDRQKE----REKDRYRERETGRDRDKERDRERQREKDRDRQK 242
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQ 63
G R R GR + R+ R + GD RR RS D +RRR+ RD R +
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 64 ERDG---NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
RD R R+R+R+R RER R R RR R G R+ K +++ R ++
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 121 GLT 123
T
Sbjct: 122 EKT 124
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 21/148 (14%)
Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
RE R+ +GR+ R R R +R + D R R DRD R++ R ++ R+R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 75 RERE-----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129
R+R+ R RERD R RR RD R+SR+R R ++
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDR-------------RRSRSRSRGRR---SRSSS 106
Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESE 157
PG + + + K D G E +
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKK 134
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/179 (19%), Positives = 73/179 (40%), Gaps = 17/179 (9%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--- 67
R+R RERD R + R R R R R + SS GN+ + + ++ DG
Sbjct: 70 RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129
Query: 68 NRDRNRDR-ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDA 126
++++ +D+ ++E E+E+D + + R W + ++ + + L +
Sbjct: 130 SKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEI 189
Query: 127 AAPPGPAPW-------EAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYY 178
W + +P + +++G+ E P + Y+ +EEV+ +
Sbjct: 190 EEMKQGKKWSLEDDDDDEDDPAEAEKEGN--EMEGEELDPLDAYMEEV----KEEVKKF 242
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 15/102 (14%)
Query: 11 RARPRERDPGRRPHPDQGR---THDRPRDRPGDPRRKRSSDGNRRRDGDR-------DPE 60
R R R RD R D+ R + R RDR + RR RS D R R R P
Sbjct: 49 RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPG 108
Query: 61 RDQERDGNRDRNRDR----ERERERERDPDRGPRRDTHRDAG 98
++ NR R++++ E +E+++D D + +DAG
Sbjct: 109 NKSKKTENRSRSKEKTDGGESSKEKKKDKD-DKEDEKEKDAG 149
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 58.5 bits (140), Expect = 1e-08
Identities = 56/171 (32%), Positives = 67/171 (39%), Gaps = 17/171 (9%)
Query: 8 REPRARPRERDPG-RRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR--DGDRDPERDQE 64
R PR R + D G RR D R+ R D PRR D RR D DR P R +
Sbjct: 1036 RGPR-RGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMD 1094
Query: 65 RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVW---EKPRQSRTRDG 118
D R D +R R D DRGP R+ D PR G + G W + R SR D
Sbjct: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154
Query: 119 ARGLTWDAAAPPG-------PAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
R + PG P W E + + G P RP E +R
Sbjct: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDR 1205
Score = 57.8 bits (138), Expect = 2e-08
Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 17/183 (9%)
Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN---RRRDGDRDPERDQERD 66
P R + D G D+ R R D PRR + D R D DR P R + D
Sbjct: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDD 1076
Query: 67 GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVWEKPRQSRTRDGARGLT 123
R D +R R D DRGPRR D GPR G + G W R RG
Sbjct: 1077 RGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRI--PRRG-- 1132
Query: 124 WDAAAPPGPAPWEAPEPPQPQRKGDPGR--RRPESEPPSERYLPSTPRPGREEVEYYQSE 181
A PW + + R+ D R RR + P + P G E E + E
Sbjct: 1133 ----AEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP-WRPLVKPGGWREKEKAREE 1187
Query: 182 AEG 184
+ G
Sbjct: 1188 SWG 1190
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/120 (35%), Positives = 54/120 (45%), Gaps = 16/120 (13%)
Query: 14 PRERDPGR----RPHPDQGRTHDRPRDRP---GDPRRKRSSDGNRRRDGDRDPERDQERD 66
PR D R RP G ++ + R G PR R S+ R+ DR+ ERD++
Sbjct: 1158 PRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSE---EREWDREKERDRDNQ 1214
Query: 67 GNRDRNRDRERERERERDPDRGPRRDTHRDAG----PRAGEHGVW--EKPRQSRTRDGAR 120
+ ++D ERER+RERD DR R RD G A E W R R RD R
Sbjct: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
Score = 50.8 bits (120), Expect = 2e-06
Identities = 51/165 (30%), Positives = 60/165 (36%), Gaps = 17/165 (10%)
Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRP---GD-----PRRKRSSDGNRRR-- 53
P E R P E++ R D+ R+H R +RP GD P + D RR
Sbjct: 903 PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGM 962
Query: 54 DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG-------PRAGEHGV 106
D DR P R E D R D +R R D DR PRR D G R G+
Sbjct: 963 DDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGL 1022
Query: 107 WEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGR 151
E RT D RG GP A + R D R
Sbjct: 1023 DEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDR 1067
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/146 (34%), Positives = 65/146 (44%), Gaps = 29/146 (19%)
Query: 2 EDPSGAREPRARPR------ERDPGRRPHPDQ----GRTHDR-PRDRPGDPR-RKRSSDG 49
ED S R+ RPR +R+P RP D+ G DR PR P + R +R +D
Sbjct: 926 EDRSHRRDEE-RPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADD 984
Query: 50 NR----RRDGDRDPER--DQERDGNRDRNRDR--------ERERERERDPDRGPRRDTHR 95
+R D DR P R D++R R + DR +R R D DRGPRR
Sbjct: 985 DRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDD 1044
Query: 96 DAGPRAGEHGVWEKPRQSRTRDGARG 121
D GPR G G ++ R D RG
Sbjct: 1045 DRGPRRG--GADDERSSWRNADDDRG 1068
Score = 47.8 bits (112), Expect = 2e-05
Identities = 53/196 (27%), Positives = 70/196 (35%), Gaps = 36/196 (18%)
Query: 4 PSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
P G RE +AR P R P + R DR ++R D + + +D + R+ DR+ + D
Sbjct: 1175 PGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVD 1234
Query: 63 QERDGNRDRN---------------RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVW 107
+E R R+ RD R +R+RD DR RD RD R
Sbjct: 1235 REDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRER------- 1286
Query: 108 EKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPST 167
R R R G P E E +R D R E P R P
Sbjct: 1287 RDLRDDRDRRGP------------PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPA 1334
Query: 168 PRPGREEVEYYQSEAE 183
RE + E E
Sbjct: 1335 LSRDRERDRDREREGE 1350
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/154 (30%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPG---DPRRKRSS--DGNRRRDGDRDPERD 62
RE + ER+ R D+ RPRD G P + SS D +RR D DRD +R
Sbjct: 1216 REENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRR 1274
Query: 63 QERDGNRD--RNRDRERERERERDPDRGPRRD--THRDAGPRAGEHGVWEK------PRQ 112
+ERD RD RD +R+R P R R + + R A R + V E+ P
Sbjct: 1275 RERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR-VEERDPPRRVPPP 1333
Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRK 146
+ +RD R + A W A + + R+
Sbjct: 1334 ALSRDRERDRDREREGEKEKASWRAEKDRESLRR 1367
Score = 31.2 bits (69), Expect = 1.7
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 27/122 (22%)
Query: 56 DRDPERDQER---DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
+R+ R++ER D + R R +R+ E +GP D+ GP E W R+
Sbjct: 867 ERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKE---W---RR 920
Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGR 172
RD R + +P+R GD R P P +R PR G
Sbjct: 921 GEGRDEDRS--------------HRRDEERPRRLGDDEDREPSLRPDDDR----VPRRGM 962
Query: 173 EE 174
++
Sbjct: 963 DD 964
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 13/98 (13%)
Query: 9 EPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG----DRDPERDQE 64
E R +ER+ R+ +Q + R++ + R R + +RR+ DR+ ER++E
Sbjct: 1240 ERAERAKEREKRRK---EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE 1296
Query: 65 RD-GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRA 101
RD G+RDR+R+R+RER RERD RRDT R + R+
Sbjct: 1297 RDRGDRDRDRERDRERGRERD-----RRDTKRHSRSRS 1329
Score = 53.9 bits (128), Expect = 3e-07
Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 8/93 (8%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
E ++ R + ER+ R+ ++ R H R RDR + R+R R D DRD ER
Sbjct: 1254 EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD-----RGDRDRDRER 1308
Query: 62 DQERDGNRDRNRDRERERERERDP---DRGPRR 91
D+ER RDR + R R R DRG RR
Sbjct: 1309 DRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Query: 35 RDRPGDPRRKRSSDGN---RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR- 90
R + + RRK + R ++ +R+ R ER+ R+ +R+R+RERERER+ DRG R
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303
Query: 91 RDTHRDAGPRAGEHGVWEKPRQSRTR 116
RD RD R E + R SR+R
Sbjct: 1304 RDRERDR-ERGRERDRRDTKRHSRSR 1328
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER-DQER 65
A+E R +E++ + ++ +R R + RR+ S + +R R+ +R+ +R D++R
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR 1304
Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTH-RDAGPR 100
D RDR R RER+R + R R T RD G R
Sbjct: 1305 DRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340
Score = 39.3 bits (90), Expect = 0.006
Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 19/168 (11%)
Query: 5 SGAREPRARPRERDP---GRRPHPD---------QGRTHDRPRDRPGDPRRKRSSDGNRR 52
S + +R R R P G R H Q RTH PR RP R S +R
Sbjct: 582 SSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRS 641
Query: 53 RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
R R + + + +RD +DP G A P + V E +
Sbjct: 642 RSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSG-----QEVATPPVPQLQVCEP--K 694
Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPS 160
RT + + + P A + QP+R E+EPP+
Sbjct: 695 ERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPA 742
Score = 36.2 bits (82), Expect = 0.054
Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 9 EPRARPRERDPGRRPHPDQGRTHDRPRDRPGD-------PRRKRSSDGNRRRDGDRDPER 61
E + PR P P P Q H R R + R+R + R +R+ +R
Sbjct: 1109 EEQGIPRPLHPPPPP-PVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR 1167
Query: 62 DQERDGNRDRNRDRERER-ERERDPDRGPRRDTHRDAGPRA 101
D+ R+G R R+R R+R R ER + ++ + P A
Sbjct: 1168 DKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPA 1208
Score = 29.6 bits (65), Expect = 5.1
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 60 ERDQERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTR 116
ER +ER+ R + +ERE+E ER+ +R R+ R+ E+ R R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302
Query: 117 DGAR 120
D R
Sbjct: 1303 DRDR 1306
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 10/120 (8%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPG-DPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
R R R R H + R+ DR DR D R++ ++ RRRD D D ER ER+ R
Sbjct: 323 RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKER 382
Query: 70 DRNRDRER---------ERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
+R+R+R + E++ + D D RD RD+ + R+ R+R +R
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR 442
Score = 46.2 bits (108), Expect = 5e-05
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 21/140 (15%)
Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR----------- 53
S +R+ + R+RD R ++GR DR D+ R++ + +R R
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399
Query: 54 ------DGDRDPERDQERDGNRDRNRDRERERERE---RDPDRGPRRDTHRDAGPRAGEH 104
D D RD +RD +++ R R RER+ R R + + + ++ +H
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Query: 105 GVWEKPRQS-RTRDGARGLT 123
K + + R+R G++G T
Sbjct: 460 KNESKEKSNKRSRSGSQGRT 479
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 2/112 (1%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
R R+ R P R P + R+H R R+ + R+R ER++ER
Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317
Query: 68 NR--DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
+R DR +R R R RER R RD D R E + + R RD
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369
Score = 42.7 bits (99), Expect = 6e-04
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 11 RARPRE-RDPGRRPHPDQGRTHDRPRDRPG--------DPRRKRSSDGNRRRDG----DR 57
+ RPR+ + G+ + R +R R R PRR RS +R G DR
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293
Query: 58 DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
+ ER++ER ++RE+ER R R DRG R R ++ R RD
Sbjct: 294 ELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRD 353
Query: 118 GAR 120
R
Sbjct: 354 RER 356
Score = 42.4 bits (98), Expect = 8e-04
Identities = 21/88 (23%), Positives = 41/88 (46%)
Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
S R+ R+R R R+ G+R + ++ + KRS G++ R + + +E
Sbjct: 430 SRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489
Query: 65 RDGNRDRNRDRERERERERDPDRGPRRD 92
+++++R R R +ER D +D
Sbjct: 490 HSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Score = 31.2 bits (69), Expect = 1.7
Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-----------DGD 56
+E + R RD R ++ + R R+R R + + G R R +
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463
Query: 57 RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHR 95
++ + R G++ R E+ ++RE P + R R
Sbjct: 464 KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR 502
Score = 28.9 bits (63), Expect = 8.6
Identities = 13/60 (21%), Positives = 28/60 (46%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
+++ RE P + + R+ +R R + +S +RRR + E +++ N+D
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58
G E + R RD R ++ + +PR++ D + + + GNR R+G+R+
Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225
Query: 59 PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99
P+ ++++D GNR+R+RD E R+R+RERD D+G RD R
Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282
Query: 100 RAGEHGVWEKPRQ 112
+ GEH W+ R+
Sbjct: 283 KNGEHS-WDLDRE 294
Score = 56.6 bits (135), Expect = 4e-08
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 39/212 (18%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
G RE RA+ R R R R DR +R + RK + R DRD ERD+++
Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273
Query: 66 DGNRDRNR--------DRERERERERDPD-------------------RGPRRDTHRDAG 98
+RDR R D +RE+ RE D + + +T +
Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIS 333
Query: 99 PRAGEHGVWEKPRQSRTRDGARG-LTWDAAAPPGPA---PWEAPEPPQ-PQRKGDPGRRR 153
RA + + K + R+++ G T DA GPA E PE P+ P RR
Sbjct: 334 TRASK-SLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRI 392
Query: 154 PESEPPSERYLPSTPRPGREE-VEYYQSEAEG 184
P P S R P+ PR R++ +E Q + G
Sbjct: 393 P--RPGSAR--PAPPRVKRQDSMEALQMDRSG 420
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%)
Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64
+R +E D + ++ R H DR ++RS+ +R++ + R+ ++D+E
Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202
Query: 65 RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111
+ NR RE ERER ER DRG R RD+ R G EK R
Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167
+ R RD +G D G W+ + R+ D P ++ S S++ T
Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320
Query: 168 PRPGREEVE 176
+ + E E
Sbjct: 321 FKDSKAETE 329
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58
G E + R RD R ++ + +PR++ D + + + GNR R+G+R+
Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225
Query: 59 PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99
P+ ++++D GNR+R+RD E R+R+RERD D+G RD R
Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282
Query: 100 RAGEHGVWEKPRQ 112
+ GEH W+ R+
Sbjct: 283 KNGEHS-WDLDRE 294
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 6 GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
G RE RA+ R R R R DR +R + RK + R DRD ERD+++
Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273
Query: 66 DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE 103
+RDR R + E + D ++ D +GE
Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGE 311
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 10/95 (10%)
Query: 5 SGAREPRARPRERDPGRRPHPDQGRTHDRP-RDRPGDPRRKRSSDGNRRRDGDRDPER-- 61
+G R RER R PD R DR R+R D RK+ ++ R+ +G ++ ER
Sbjct: 207 NGGNRHREGERERAKARA-RPDNERQKDRGNRERDRDSERKKETE--RKSEGGKEKERLR 263
Query: 62 DQERDGNRDRNRDRERER----ERERDPDRGPRRD 92
D++R+ +RD+ +DR+R R E D DR R+
Sbjct: 264 DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%)
Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64
+R +E D + ++ R H DR ++RS+ +R++ + R+ ++D+E
Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202
Query: 65 RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111
+ NR RE ERER ER DRG R RD+ R G EK R
Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167
+ R RD +G D G W+ + R+ D P ++ S S++ T
Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320
Query: 168 PRPGREEVE 176
+ + E E
Sbjct: 321 FKDSKAETE 329
Score = 32.0 bits (71), Expect = 1.0
Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 14/83 (16%)
Query: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
+D R R+++ R+ + + R RDR RD D+ +R
Sbjct: 232 KDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE--------------RDRDKGKDR 277
Query: 62 DQERDGNRDRNRDRERERERERD 84
D+ R N + + D +RE+ RE D
Sbjct: 278 DRRRVKNGEHSWDLDREKNREHD 300
>gi|125988409 RED protein [Homo sapiens]
Length = 557
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 11/150 (7%)
Query: 6 GAREPRARPRER---DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
G R + + +++ + + P D D P + R + R R+ +RD ERD
Sbjct: 292 GTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGL 122
++RD R+R RDRERERER+R+ + +R ++ + P+ + + T++ + +
Sbjct: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEK-PKVDDEPMDVDKGPGSTKELIKSI 410
Query: 123 TWDAAAPPGPAPWEAPE----PPQPQRKGD 148
A G A WE E P ++ GD
Sbjct: 411 NEKFA---GSAGWEGTESLKKPEDKKQLGD 437
Score = 45.4 bits (106), Expect = 9e-05
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 26/80 (32%)
Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
PS + PR + RER R+R D R RD DR ER++
Sbjct: 327 PSTTKTPRDKERER------------------------YRERERDRERDRDRDR--ERER 360
Query: 64 ERDGNRDRNRDRERERERER 83
ERD R+R RDRERE E++R
Sbjct: 361 ERDRERERERDREREEEKKR 380
Score = 32.7 bits (73), Expect = 0.60
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 10 PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
PRA P P + H + R ++ D P RRK+ S + R + + ER+ +
Sbjct: 43 PRAAPTSAPPSKSRHHEMPREYNEDED-PAARRRKKKSYYAKLRQQEIEREREL---AEK 98
Query: 70 DRNRDRERERERERDPDRGPRRDT---HRDAGPRA-GEHGVWEKPRQ 112
R+R +ER +D + T +R GP A + EK RQ
Sbjct: 99 YRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145
>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
Length = 520
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G
Sbjct: 382 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 440
Query: 107 WEKPRQSRTRD 117
+E+ R SR ++
Sbjct: 441 YERHRASREKE 451
Score = 45.8 bits (107), Expect = 7e-05
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
+R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E
Sbjct: 386 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 445
Query: 107 WEKPRQSRTRD 117
+ ++ R R+
Sbjct: 446 ASREKEERHRE 456
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
D + D R D R+R D R RD DR+ ER +ER+ RD N D ER
Sbjct: 372 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 431
Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R RE +RG R ++ R H E+ R +R +R
Sbjct: 432 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 475
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
AR + R RERD R ++ R DR R+R + R+R +SD R R
Sbjct: 381 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 436
Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
+R ER + +R+R+R R RE+E + R ++ R G+ H + +
Sbjct: 437 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 495
Query: 114 RTRDGARGLTWDAAAPPGP 132
R+++G +A + P P
Sbjct: 496 RSKEGK-----EAGSEPAP 509
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G
Sbjct: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 508
Query: 107 WEKPRQSRTRD 117
+E+ R SR ++
Sbjct: 509 YERHRASREKE 519
Score = 45.8 bits (107), Expect = 7e-05
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
+R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E
Sbjct: 454 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 513
Query: 107 WEKPRQSRTRD 117
+ ++ R R+
Sbjct: 514 ASREKEERHRE 524
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
D + D R D R+R D R RD DR+ ER +ER+ RD N D ER
Sbjct: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R RE +RG R ++ R H E+ R +R +R
Sbjct: 500 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 543
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
AR + R RERD R ++ R DR R+R + R+R +SD R R
Sbjct: 449 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 504
Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
+R ER + +R+R+R R RE+E + R ++ R G+ H + +
Sbjct: 505 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
Query: 114 RTRDGARGLTWDAAAPPGP 132
R+++G +A + P P
Sbjct: 564 RSKEGK-----EAGSEPAP 577
>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
Length = 594
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Query: 52 RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
RR+ DRD ERD++R+ +RDR+R+RER RERER+ D P D R E G
Sbjct: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 514
Query: 107 WEKPRQSRTRD 117
+E+ R SR ++
Sbjct: 515 YERHRASREKE 525
Score = 45.8 bits (107), Expect = 7e-05
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 50 NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
+R R+ DRD ERD++RD R+R R+RERER+ P + R +R+ R E
Sbjct: 460 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 519
Query: 107 WEKPRQSRTRD 117
+ ++ R R+
Sbjct: 520 ASREKEERHRE 530
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
D + D R D R+R D R RD DR+ ER +ER+ RD N D ER
Sbjct: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
Query: 79 RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
R RE +RG R ++ R H E+ R +R +R
Sbjct: 506 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 549
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
AR + R RERD R ++ R DR R+R + R+R +SD R R
Sbjct: 455 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 510
Query: 55 GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
+R ER + +R+R+R R RE+E + R ++ R G+ H + +
Sbjct: 511 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
Query: 114 RTRDGARGLTWDAAAPPGP 132
R+++G +A + P P
Sbjct: 570 RSKEGK-----EAGSEPAP 583
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 54.7 bits (130), Expect = 1e-07
Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR 71
A P + + R PD+ R DR R RKR +RRR G R R + + R+R
Sbjct: 13 ASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERER 72
Query: 72 NRDRERERERERD---PDRGPRRDTHR 95
R +ERER++ERD DR +D HR
Sbjct: 73 -RHKERERDKERDRNKKDRDRDKDGHR 98
Score = 50.8 bits (120), Expect = 2e-06
Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 13/118 (11%)
Query: 3 DPSGAREPRARPR------ERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD 56
D S ++E R R R +RD R+ P + R R RDR R RS ++ + +
Sbjct: 12 DASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE 71
Query: 57 RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114
R +++ERD RDRN+ ++R+R++D G RRD R + G K R+ R
Sbjct: 72 RR-HKERERDKERDRNK---KDRDRDKD---GHRRDKDRKRSSLSPGRGKDFKSRKDR 122
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 30/203 (14%)
Query: 2 EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-----RRRDG 55
E+ +R P R R R+RD P D+ R R R R G R RS + R ++
Sbjct: 18 EERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKER 77
Query: 56 DRDPERDQ---ERDGNRDRNRDRERERERER-DPDRGPRRDTHRDAGPR---AGEHGVWE 108
+RD ERD+ +RD ++D +R R+++R+R P RG + +D + EHG +
Sbjct: 78 ERDKERDRNKKDRDRDKDGHR-RDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD-K 135
Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPP----QPQRKGDPGRRRPESEPPSERYL 164
KP+ A+ L+ + A EA P + +R+ + +RR + +R L
Sbjct: 136 KPK-------AQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRML 188
Query: 165 PSTPRPGREEVEYYQSEAEGLLE 187
R++ + +Q +LE
Sbjct: 189 EEE----RKKRKQFQDLGRKMLE 207
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 38 PGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRER--ERERERDPDRGPRRDTHR 95
P RKRS +R RD DRD + +D R R+RDR R R R R + R+
Sbjct: 15 PSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRH 74
Query: 96 DAGPRAGEHGVWEKPRQSRTRDGAR 120
R E +K R R +DG R
Sbjct: 75 KERERDKERDRNKKDR-DRDKDGHR 98
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%)
Query: 40 DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGP 99
D + + +S R R P+R+++RD +R + ++R+R R RD RG R R
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 100 RAGEHGVWEKPRQSRTRDGAR 120
A E+ + R RD R
Sbjct: 67 SAER----ERRHKERERDKER 83
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
R RD +R H R D R +RS R R+ +RD RD RD RDR RD
Sbjct: 629 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 686
Query: 75 RERERER--ERDPDRGPR 90
RERERER +RD DRG R
Sbjct: 687 RERERERLCDRDRDRGER 704
Score = 52.4 bits (124), Expect = 7e-07
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62
A P+A P G P P + R D R D R D R+ + + RR R+ +R+
Sbjct: 609 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 666
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100
+ERD RD RDRER+R R+R+ +R D RD G R
Sbjct: 667 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 704
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 6 GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54
G +P P + P + HP H P + R KR D + R D
Sbjct: 595 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 652
Query: 55 --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
G R R+++R+ RDR RD R+RER+R DR R+ D GE G + +
Sbjct: 653 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 709
>gi|10190682 chromobox homolog 8 [Homo sapiens]
Length = 389
Score = 54.7 bits (130), Expect = 1e-07
Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
Query: 53 RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
RD DRD +RD+ERD R+R R+RERERERER+ +RG R + + P KPR+
Sbjct: 148 RDRDRDRDRDRERD--RERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRK 205
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Query: 69 RDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAA 128
RDR+RDR+R+RER+R+ +R R+ R+ G V +KP D++
Sbjct: 148 RDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSS----------PGDSSK 197
Query: 129 PPGPAPWEAPEPPQPQRKGDP 149
GP P + P + G+P
Sbjct: 198 KRGPKPRKELPDPSQRPLGEP 218
Score = 34.3 bits (77), Expect = 0.21
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 21/75 (28%)
Query: 26 DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDP 85
D+ R D RD +RD ER++ER+ R+R R+RER R D
Sbjct: 149 DRDRDRD--------------------RDRERDRERERERERERERERERERGTSRVDDK 188
Query: 86 DRGPRRDTHRDAGPR 100
P D+ + GP+
Sbjct: 189 PSSP-GDSSKKRGPK 202
Score = 33.5 bits (75), Expect = 0.35
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 11/84 (13%)
Query: 76 ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDAAAPPGPAP 134
E R+R+RD DR RD R+ E+ R+ R R+ RG + P P
Sbjct: 145 EAPRDRDRDRDRDRERDRERER----------ERERERERERERERGTSRVDDKPSSPGD 194
Query: 135 WEAPEPPQPQRKGDPGRRRPESEP 158
P+P+++ +RP EP
Sbjct: 195 SSKKRGPKPRKELPDPSQRPLGEP 218
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 15 RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
R RD +R H R D R +RS R R+ +RD RD RD RDR RD
Sbjct: 647 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
Query: 75 RERERER--ERDPDRGPR 90
RERERER +RD DRG R
Sbjct: 705 RERERERLCDRDRDRGER 722
Score = 52.4 bits (124), Expect = 7e-07
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62
A P+A P G P P + R D R D R D R+ + + RR R+ +R+
Sbjct: 627 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 684
Query: 63 QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100
+ERD RD RDRER+R R+R+ +R D RD G R
Sbjct: 685 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 722
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 6 GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54
G +P P + P + HP H P + R KR D + R D
Sbjct: 613 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 670
Query: 55 --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
G R R+++R+ RDR RD R+RER+R DR R+ D GE G + +
Sbjct: 671 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 52.8 bits (125), Expect = 6e-07
Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 21/164 (12%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPR---------DRPGDPRRKRSSDGNRRRDGDRD 58
R+ +R ER PG P P + R DR R D+ + RR RS D RR
Sbjct: 213 RDDTSRYDER-PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK 271
Query: 59 PERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG 118
ER + R+ ++D++RDR+R R R+ RR+ R R G G +P ++
Sbjct: 272 EERRRSRERSKDKDRDRKRRSSRSRE---RARRERERKEELRGG-GGDMAEPSEAGDAPP 327
Query: 119 ARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
G PPG + P+ P+ + + RR ER
Sbjct: 328 DDG-------PPGELGPDGPDGPEEKGRDRDRERRRSHRSERER 364
Score = 49.3 bits (116), Expect = 6e-06
Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 48/151 (31%)
Query: 8 REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-------------- 53
R R+R R R R ++ R+ +R +D+ D +R+ S R R
Sbjct: 255 RRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGG 314
Query: 54 -----------------------DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR 90
DG PE ++ RD +R+R R ERER RD DR
Sbjct: 315 DMAEPSEAGDAPPDDGPPGELGPDGPDGPE-EKGRDRDRERRRSHRSERERRRDRDRDRD 373
Query: 91 RDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
RD G R E G RD ARG
Sbjct: 374 RDREHKRGERGSERG----------RDEARG 394
Score = 48.9 bits (115), Expect = 8e-06
Identities = 41/130 (31%), Positives = 55/130 (42%), Gaps = 26/130 (20%)
Query: 3 DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
D RE R R RERD R R R RDR R + + R R+ +D +RD
Sbjct: 234 DRDRERERRERSRERDKERE------RRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRD 287
Query: 63 QERDGNRDRNRDRERERERERD------------------PDRGPRRDTHRDAGPRAGEH 104
++R +R R R R RERER+ + PD GP + D GP E
Sbjct: 288 RKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD-GPDGPEE 345
Query: 105 GVWEKPRQSR 114
++ R+ R
Sbjct: 346 KGRDRDRERR 355
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
Query: 7 AREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPERDQER 65
AR R R E G + D P D P DG + DRD ER +
Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSH 358
Query: 66 DGNRDRNRDRERERERERDPDRGPR-----RDTHRDAG 98
R+R RDR+R+R+R+R+ RG R RD R G
Sbjct: 359 RSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGG 396
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/171 (31%), Positives = 67/171 (39%), Gaps = 42/171 (24%)
Query: 26 DQGRTHD--RPRDRPGD--PRRKRSSDGNRRRDGDRDPERDQERDGNRDR-NRDRERERE 80
++GRT RPR G R+ +D N R G D R ER G +RDR+R+RE
Sbjct: 179 ERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRE 238
Query: 81 -------RERDPDRGPRRDTHRDAGPRAGEHGVWE---------------KPRQSRTRDG 118
RERD +R RR RD R+ E K R SR+R+
Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRER 298
Query: 119 A----------RGLTWDAAAP--PGPAPWEAPEPPQPQRKGDPGRRRPESE 157
A RG D A P G AP P+ P G G PE +
Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAP---PDDGPPGELGPDGPDGPEEK 346
Score = 35.8 bits (81), Expect = 0.071
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 27/85 (31%)
Query: 4 PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
P G P + R+RD RR R+H R+ RRRD DRD +RD+
Sbjct: 337 PDGPDGPEEKGRDRDRERR------RSHRSERE--------------RRRDRDRDRDRDR 376
Query: 64 ERDGNRDRNRDRERERERERDPDRG 88
E ++ ER ER RD RG
Sbjct: 377 E-------HKRGERGSERGRDEARG 394
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 52.0 bits (123), Expect = 1e-06
Identities = 48/168 (28%), Positives = 66/168 (39%), Gaps = 32/168 (19%)
Query: 3 DPSGAREPRARPRERDP--GRRPHPDQGRTHDRPRDRPGDPRR----KRSSDGN------ 50
DP G+RE +P E G PD G RP+DR + RR +R++ N
Sbjct: 1265 DPKGSREYSRQPNEHHTWNGTSRKPDSGAC--RPKDRAPEGRRDAQAERAAAANGPKRRS 1322
Query: 51 --RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
+RR+G R + ER ++ RD ER RER P R RD P +
Sbjct: 1323 PEKRREGTRSADNTLERREKHEKRRDVSPERRRERSPTR------RRDGSPSRRRRSLER 1376
Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPES 156
Q R+ + R G +P + +R P RRR S
Sbjct: 1377 LLEQRRSPERRR----------GGSPERRAKSTDRRRARSPERRRERS 1414
Score = 37.0 bits (84), Expect = 0.032
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 8 REPRARPRERD--PGRRPHPDQGRTHDR---PRDRPGDP-RRKRSSDGNRRRDGDRDPER 61
R R+ R RD P RR + R R R G P RR +S+D R R +R ER
Sbjct: 1354 RRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRRARSPERRRER 1413
Query: 62 DQERDGNRDRNRDRERERER-ERDPDRGPRRDTHRDAGP 99
++ DR RERE ++D R R + P
Sbjct: 1414 SLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRP 1452
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 51.2 bits (121), Expect = 2e-06
Identities = 37/103 (35%), Positives = 46/103 (44%), Gaps = 10/103 (9%)
Query: 35 RDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTH 94
RDR +R RS D NR RD DR+ RD++ R R+R R R R RER+ + R
Sbjct: 168 RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHK-RRHRSRSRSRSRTRERNKVKSRYRSRS 226
Query: 95 RDAGPRAGEHGVWEKPRQSRTRDGARGL-TWDAAAPPGPAPWE 136
R P K R+ R + G R L W P P E
Sbjct: 227 RSQSP--------PKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261
Score = 45.8 bits (107), Expect = 7e-05
Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Query: 51 RRRDGD-RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
++RD + RD + ++R +RDRNRDR+R+RER RD D R + + R E +
Sbjct: 161 KQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKS 220
Query: 110 PRQSRTR 116
+SR+R
Sbjct: 221 RYRSRSR 227
Score = 45.4 bits (106), Expect = 9e-05
Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 15/108 (13%)
Query: 4 PSGAREPRARPRE-RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
PS A + + R E RD R + R+ DR RDR D R R D ++RR R R
Sbjct: 154 PSAAGQEKQRDAEHRD--RTKKKKRSRSRDRNRDRDRDRERNRDRD-HKRRHRSRSRSRS 210
Query: 63 QERDGNRDRNRDRERERERERDPDRGPR-----------RDTHRDAGP 99
+ R+ N+ ++R R R R + DR R RD H D P
Sbjct: 211 RTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPP 258
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 11 RARPRERDPGRRPHPDQGRTH-DRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ-ERDGN 68
R R R+RD R D R H R R R R + R R + P +D+ +RD
Sbjct: 182 RNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY 241
Query: 69 RDRNRDRERERERERDPDRGP 89
+RN DR R++ +R P P
Sbjct: 242 GERNLDRWRDKHVDRPPPEEP 262
Score = 38.1 bits (87), Expect = 0.014
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 11 RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
R R R+RD RR H + R+ R R+R R RS ++ DR +RD+ + N D
Sbjct: 190 RERNRDRDHKRR-HRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRK-DRDKYGERNLD 247
Query: 71 RNRDRERERERERDPDRG 88
R RD+ +R +P G
Sbjct: 248 RWRDKHVDRPPPEEPTIG 265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.140 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,229,793
Number of Sequences: 37866
Number of extensions: 1277270
Number of successful extensions: 17761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 290
Number of HSP's successfully gapped in prelim test: 705
Number of HSP's that attempted gapping in prelim test: 9541
Number of HSP's gapped (non-prelim): 4512
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.