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Search of human proteins with 61742808
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo
sapiens]
(1484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 2979 0.0
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 2979 0.0
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 537 e-152
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 308 3e-83
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 307 6e-83
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 2e-13
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 68 8e-11
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 65 5e-10
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 65 5e-10
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 63 2e-09
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 63 2e-09
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 62 4e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 4e-09
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 62 5e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 61 9e-09
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 59 5e-08
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 59 5e-08
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 57 1e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 57 1e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens] 57 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 57 2e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 57 2e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 56 3e-07
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 55 4e-07
gi|73476377 LBXCOR1 homolog [Homo sapiens] 55 4e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 55 5e-07
gi|157785645 SPEG complex locus [Homo sapiens] 55 7e-07
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 55 7e-07
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 54 9e-07
gi|33286446 opioid growth factor receptor [Homo sapiens] 54 1e-06
>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
Length = 1484
Score = 2979 bits (7722), Expect = 0.0
Identities = 1484/1484 (100%), Positives = 1484/1484 (100%)
Query: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR
Sbjct: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
Query: 61 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 120
SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP
Sbjct: 61 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 120
Query: 121 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 180
YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK
Sbjct: 121 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 180
Query: 181 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 240
DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA
Sbjct: 181 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 240
Query: 241 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 300
ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA
Sbjct: 241 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 300
Query: 301 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 360
SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP
Sbjct: 301 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 360
Query: 361 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 420
KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF
Sbjct: 361 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 420
Query: 421 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 480
GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP
Sbjct: 421 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 480
Query: 481 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 540
QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP
Sbjct: 481 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 540
Query: 541 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 600
VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD
Sbjct: 541 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 600
Query: 601 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 660
SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS
Sbjct: 601 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 660
Query: 661 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 720
EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG
Sbjct: 661 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 720
Query: 721 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP
Sbjct: 721 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
Query: 781 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 840
GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT
Sbjct: 781 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 840
Query: 841 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 900
HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG
Sbjct: 841 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 900
Query: 901 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 960
PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA
Sbjct: 901 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 960
Query: 961 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1020
IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA
Sbjct: 961 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1020
Query: 1021 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1080
AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP
Sbjct: 1021 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1080
Query: 1081 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1140
EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT
Sbjct: 1081 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1140
Query: 1141 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1200
MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD
Sbjct: 1141 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1200
Query: 1201 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1260
DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL
Sbjct: 1201 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1260
Query: 1261 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1320
SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR
Sbjct: 1261 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1320
Query: 1321 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1380
NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL
Sbjct: 1321 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1380
Query: 1381 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1440
KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS
Sbjct: 1381 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1440
Query: 1441 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1484
PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI
Sbjct: 1441 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1484
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapiens]
Length = 1554
Score = 2979 bits (7722), Expect = 0.0
Identities = 1484/1484 (100%), Positives = 1484/1484 (100%)
Query: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR
Sbjct: 71 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 130
Query: 61 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 120
SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP
Sbjct: 131 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 190
Query: 121 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 180
YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK
Sbjct: 191 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 250
Query: 181 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 240
DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA
Sbjct: 251 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 310
Query: 241 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 300
ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA
Sbjct: 311 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 370
Query: 301 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 360
SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP
Sbjct: 371 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 430
Query: 361 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 420
KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF
Sbjct: 431 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 490
Query: 421 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 480
GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP
Sbjct: 491 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 550
Query: 481 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 540
QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP
Sbjct: 551 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 610
Query: 541 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 600
VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD
Sbjct: 611 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 670
Query: 601 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 660
SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS
Sbjct: 671 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 730
Query: 661 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 720
EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG
Sbjct: 731 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 790
Query: 721 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP
Sbjct: 791 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 850
Query: 781 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 840
GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT
Sbjct: 851 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 910
Query: 841 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 900
HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG
Sbjct: 911 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 970
Query: 901 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 960
PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA
Sbjct: 971 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 1030
Query: 961 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1020
IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA
Sbjct: 1031 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1090
Query: 1021 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1080
AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP
Sbjct: 1091 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1150
Query: 1081 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1140
EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT
Sbjct: 1151 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1210
Query: 1141 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1200
MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD
Sbjct: 1211 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1270
Query: 1201 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1260
DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL
Sbjct: 1271 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1330
Query: 1261 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1320
SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR
Sbjct: 1331 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1390
Query: 1321 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1380
NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL
Sbjct: 1391 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1450
Query: 1381 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1440
KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS
Sbjct: 1451 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1510
Query: 1441 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1484
PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI
Sbjct: 1511 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1554
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapiens]
Length = 1584
Score = 537 bits (1384), Expect = e-152
Identities = 495/1584 (31%), Positives = 744/1584 (46%), Gaps = 295/1584 (18%)
Query: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ+S K +
Sbjct: 71 VRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESEL 130
Query: 61 SEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQPSWWGEDDGST 110
S++ + + ++ E K + + +A R TPLYGQPSWWG+D+
Sbjct: 131 SKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDE 190
Query: 111 LPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSYFEIPTKETPQ 165
+ G+P + + G ++ A A + F REPSYFEIPTKE Q
Sbjct: 191 KRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQ 250
Query: 166 PSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQR 225
PSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+DH+TKF+ QR
Sbjct: 251 PSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRDHVTKFTSDQR 306
Query: 226 RPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHT 276
K+++PG M++ E KVADWL QN+P + +D S KSD+PV+
Sbjct: 307 H-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYL 365
Query: 277 RTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVI 336
+ LKG+KH+DGTQSDSE+ AG S ++ L+ ++R E Q+
Sbjct: 366 KRLKGNKHDDGTQSDSEN--------AGAHRRCS-KRATLEEHLRRHHSEHKKLQKVQAT 416
Query: 337 EFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGS 396
E K + Q+ T S A R G VP G
Sbjct: 417 E--------KHQDQAVTSS------AHHRGG--------HGVP--------------HGK 440
Query: 397 LKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVL 456
L ++K+EE S R GS+G R D M + + A + EK
Sbjct: 441 LLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLK-----NQATSATSEK----- 490
Query: 457 PAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARK 516
+ DD SD GTYTIE E ++E EARK
Sbjct: 491 --------------------------------DNDDDQSDKGTYTIELENPNSEEVEARK 518
Query: 517 MIDQVFGVLESPELSRASSATFRPVI-RGDRDESDDGGVAQRMALLQEFASRPLGAAPQA 575
MID+VFGV ++ + + RPVI +D D ++ A+++E +PL
Sbjct: 519 MIDKVFGVDDNQDYN-------RPVINEKHKDLIKDWALSSAAAVMEE--RKPL--TTSG 567
Query: 576 EHQGLPVPGSPGGQKWVSRWASLADSY-------------------SDPGLTEDGLGRRG 616
H S G ++WVS+WASLA ++ ++ ++E G+ R
Sbjct: 568 FHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRS 627
Query: 617 GEPEGSLP---VRMRRRLPQLPSER--ADSPAGPESSRRSGPGPPE----LDSEQPSRLF 667
SL R RR LPQLP+E +S ++RS G + + E P++++
Sbjct: 628 TGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVY 687
Query: 668 GQEELDPD-SLSDASGSDGGR---------------GPEPGVEPQDSRRRSPQEGPTWSR 711
+++ D D LS + + G PG E ++ + + T ++
Sbjct: 688 QKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAK 747
Query: 712 -GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSA 770
++ R + TP + +G R+ E Q +Q PP ++ + ++
Sbjct: 748 LQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQ--PPEKNSGHSTS 797
Query: 771 NGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPPAPGKP---- 813
G V Q R S P G + + +RQ SFT E P+P P
Sbjct: 798 KGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIE----KPSPNIPIELI 853
Query: 814 PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALAALEARLL-S 860
PHI SS P LA T A+R+ S+ DT LILK+TE +A LEA+L
Sbjct: 854 PHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLRED 911
Query: 861 NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP--LRAQKEMSP 917
N D EG TP D ++S +SDVDTAST+SL +G++ T + K+
Sbjct: 912 NKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCS 968
Query: 918 SPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEE 977
+ ++D ++ ARE+ ++ TD+G R+ G + S+D ++
Sbjct: 969 TGSPSKDVTKSSSSGAREKMEKKTKS--RSTDVGSRADGRKFVQSSGRIRQPSVDLTDDD 1026
Query: 978 RGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGP- 1036
+ + H SD+M+S+ ET G R P + + S+ P
Sbjct: 1027 QTSSVPHSAISDIMSSDQETYSCKPHG-----RTPLTSADEHVHSKLEGSKVTKSKTSPV 1081
Query: 1037 --QALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLG---------NPEPVGR 1085
+ ++S +L PRPTR S LRRARLG+ASD+E AD ++ S+ + P GR
Sbjct: 1082 VSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGR 1141
Query: 1086 PAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE--------LCCAS 1136
+ +SR+D+LA PR+ R GS + SD EA +R+S S R+ E L +
Sbjct: 1142 ------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSD 1195
Query: 1137 RKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ------------- 1179
+ A ++SR K + + G SR R Y ST++
Sbjct: 1196 KFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1255
Query: 1180 ---TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEIARLSQTLVKDVAI 1234
T A ++R +S P + + +I TA EIAR+SQ D+A+
Sbjct: 1256 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQ----DLAL 1311
Query: 1235 LAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPP- 1293
+A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+ + SLNF+K+PP
Sbjct: 1312 IAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPL 1371
Query: 1294 --------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIREN 1345
+ S D + + + R +R+EV+ DNL+L+ V Q S+ IR++
Sbjct: 1372 VHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQS 1431
Query: 1346 TEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILKELRRVQKQLEVIN 1405
+ A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+EL+RV+KQL+ IN
Sbjct: 1432 IDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAIN 1491
Query: 1406 AIVDPSGSLDLLTGNRSLASSAQP 1429
A++DP G+L+ L N S+ P
Sbjct: 1492 AMIDPDGTLEAL-NNMGFPSAMLP 1514
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapiens]
Length = 1460
Score = 308 bits (788), Expect = 3e-83
Identities = 316/1042 (30%), Positives = 490/1042 (47%), Gaps = 185/1042 (17%)
Query: 510 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 566
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
Query: 567 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 607
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
Query: 608 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 658
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
Query: 659 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 702
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
Query: 703 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 761
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
Query: 762 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 808
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
Query: 809 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 852
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
Query: 853 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 908
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
Query: 909 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 968
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
Query: 969 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1027
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
Query: 1028 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1080
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
Query: 1081 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1131
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
Query: 1132 LCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARS-GSARYTSTTQTPRAGS----S 1186
S + + R AN+ + + S + GSA TT+ AGS S
Sbjct: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSAMPTS 1144
Query: 1187 SRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDG 1246
S + R D D TA EIAR+SQ D+A++A+EI+DVAG+
Sbjct: 1145 SSFKHRIKEQEDYIRD-----------WTAHREEIARISQ----DLALIAREINDVAGEI 1189
Query: 1247 DTLGSSEPAHSASLSNMPSTPASTISAREE----------LVQRIPEASLNFQKVPP--- 1293
D++ SS A S ++S +TP S I REE LV R+ + SLNF+K+PP
Sbjct: 1190 DSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVH 1249
Query: 1294 ------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTE 1347
+ S D + + + R +R+EV+ DNL+L+ V Q S+ IR++ +
Sbjct: 1250 SKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSID 1309
Query: 1348 HLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILKELRRVQKQLEVINAI 1407
A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+EL+RV+KQL+ INA+
Sbjct: 1310 KTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAM 1369
Query: 1408 VDPSGSLDLLTGNRSLASSAQP 1429
+DP G+L+ L N S+ P
Sbjct: 1370 IDPDGTLEAL-NNMGFPSAMLP 1390
Score = 225 bits (574), Expect = 2e-58
Identities = 138/332 (41%), Positives = 191/332 (57%), Gaps = 29/332 (8%)
Query: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ+S K +
Sbjct: 71 VRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESEL 130
Query: 61 SEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQPSWWGEDDGST 110
S++ + + ++ E K + + +A R TPLYGQPSWWG+D+
Sbjct: 131 SKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDE 190
Query: 111 LPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSYFEIPTKETPQ 165
+ G+P + + G ++ A A + F REPSYFEIPTKE Q
Sbjct: 191 KRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQ 250
Query: 166 PSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQR 225
PSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+DH+TKF+ QR
Sbjct: 251 PSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRDHVTKFTSDQR 306
Query: 226 RPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHT 276
K+++PG M++ E KVADWL QN+P + +D S KSD+PV+
Sbjct: 307 H-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYL 365
Query: 277 RTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 308
+ LKG+KH+DGTQSDSE+ A + LE
Sbjct: 366 KRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 307 bits (786), Expect = 6e-83
Identities = 316/1057 (29%), Positives = 496/1057 (46%), Gaps = 189/1057 (17%)
Query: 510 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 566
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
Query: 567 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 607
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
Query: 608 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 658
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
Query: 659 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 702
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
Query: 703 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 761
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
Query: 762 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 808
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
Query: 809 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 852
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
Query: 853 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 908
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
Query: 909 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 968
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
Query: 969 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1027
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
Query: 1028 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1080
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
Query: 1081 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1131
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
Query: 1132 --------LCCASRKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ 1179
L + + A ++SR K + + G SR R Y ST++
Sbjct: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
Query: 1180 ----------------TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEI 1221
T A ++R +S P + + +I TA EI
Sbjct: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
Query: 1222 ARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRI 1281
AR+SQ D+A++A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+
Sbjct: 1205 ARISQ----DLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
Query: 1282 PEASLNFQKVPP---------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLML 1332
+ SLNF+K+PP + S D + + + R +R+EV+ DNL+L
Sbjct: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
Query: 1333 NPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILK 1392
+ V Q S+ IR++ + A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+
Sbjct: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
Query: 1393 ELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQP 1429
EL+RV+KQL+ INA++DP G+L+ L N S+ P
Sbjct: 1381 ELKRVEKQLQAINAMIDPDGTLEAL-NNMGFPSAMLP 1416
Score = 225 bits (574), Expect = 2e-58
Identities = 138/332 (41%), Positives = 191/332 (57%), Gaps = 29/332 (8%)
Query: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ+S K +
Sbjct: 71 VRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESEL 130
Query: 61 SEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQPSWWGEDDGST 110
S++ + + ++ E K + + +A R TPLYGQPSWWG+D+
Sbjct: 131 SKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDE 190
Query: 111 LPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSYFEIPTKETPQ 165
+ G+P + + G ++ A A + F REPSYFEIPTKE Q
Sbjct: 191 KRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQ 250
Query: 166 PSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQR 225
PSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+DH+TKF+ QR
Sbjct: 251 PSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRDHVTKFTSDQR 306
Query: 226 RPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHT 276
K+++PG M++ E KVADWL QN+P + +D S KSD+PV+
Sbjct: 307 H-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYL 365
Query: 277 RTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 308
+ LKG+KH+DGTQSDSE+ A + LE
Sbjct: 366 KRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 76.3 bits (186), Expect = 2e-13
Identities = 274/1221 (22%), Positives = 421/1221 (34%), Gaps = 191/1221 (15%)
Query: 73 ASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGS-TLPDAQRQGEPYPERPKGPVQQ 131
+S+P P++ + P ++ S +P S GS T P A Q R
Sbjct: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
Query: 132 DGELHGFRAPAEPQGCSFRREPSY-FEIPTKETPQPSQPPE--VPAHEMPTKDAEAGGGG 188
D EL R P+ CS P P +++P S P+ V A P + + +G
Sbjct: 878 DPELKS-RTPSR-HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSS 935
Query: 189 AAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWL 248
+P + + SP + ++S P + P + +
Sbjct: 936 PSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE---TPPRQSHSGS 992
Query: 249 VQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAAS--AAGVP 306
+ P + + PG +KS P K +D L+ A ++ P
Sbjct: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQE-------KSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 307 LEA--SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADK 364
E+ ++L+ Q + P V + E + +SQ+ PK +
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT-------SPKGGR 1098
Query: 365 RRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVG 424
R +P P G S+ P LK + E+ S +S P S+
Sbjct: 1099 SRSSSPVTELASRSPIRQDRGEFSASPM----LKSGMSPEQSRFQSDSSSYPTVDSNSLL 1154
Query: 425 RRSRL----AQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPT--PPPAPT 478
+SRL +++ MA +E + A+ P + P P +S V T PP
Sbjct: 1155 GQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE-SSLVFKDTLRTPPRER 1213
Query: 479 DPQLTKARKQEEDDSLSDAGTYTIETEAQDTE----VEEARKMIDQVFGVLESPELSRAS 534
+ +E++ +L T +QD E VE++ + Q+ L S EL S
Sbjct: 1214 SGAGSSPETKEQNSALP--------TSSQDEELMEVVEKSEEPAGQILSHLSS-ELKEMS 1264
Query: 535 SATF--------RPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPG-- 584
++ F RP + D+S QA + + VP
Sbjct: 1265 TSNFESSPEVEERPAVSLTLDQSQS----------------------QASLEAVEVPSMA 1302
Query: 585 -SPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPA 643
S GG + L++S L E+ G P+ R P L +E +
Sbjct: 1303 SSWGGPHFSPEHKELSNS----PLRENSFGS---------PLEFRNSGP-LGTEMNTGFS 1348
Query: 644 GPESSRRSGP------GPPELD-SEQPSRLFGQE--ELDPDSLSDASGSDGGRGPEP--- 691
+GP P LD EQ +R G EL PD++ A S P
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD 1408
Query: 692 GVEPQDSRRRSPQ-EGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGE 750
V SR RS P G PR P + + G ++G SR L+ G
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDGL--PRTPSRRSRSGSSPGLRDGSGTPSRHSLS--GSSP 1464
Query: 751 GLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKE-PASGPPA 809
G+ + R S + + Q RS P P L + T + SG +
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE---LNNKCLTPQRERSGSES 1521
Query: 810 PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEG 869
++ PL Q + + +D A+ + R S+S
Sbjct: 1522 SVDQKTVARTPLGQRSRSGSSQELDVKPS-------------ASPQERSESDSSPDSKAK 1568
Query: 870 GSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEM---SPSPPAAQDPG 926
TP +VD+ S +S R +SG SP RA S S P + P
Sbjct: 1569 TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 927 GTALVS-AREQSSERQHHPL----GPTDMGRGEPVRRSAIRRGHR----PRGSLDWPSEE 977
AL +R SS + P T+ P + RRG R P+ P
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
Query: 978 RG----PVL---AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR--- 1027
R P L A L AS+ +PE RR P+ P PA + SR
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASS--SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 1028 ------SSASSQKG------PQALTRSNSLSTPRPTRASRLR----------RARLGDAS 1065
+ +S++G P+ L RS S S TR +R R R R S
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
Query: 1066 DTEAADGERGSLG--NPEPVGRPAAEQAKKLSRLDILAMP--RKRAGSFTGT-----SDP 1116
+ RG G + P + ++ + + R P RKR+ S T S
Sbjct: 1807 RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRS 1866
Query: 1117 EAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTS 1176
A+PA S L SR+ + + VSR+ + + T+ R+ SRA S +R S
Sbjct: 1867 RASPATHRRSRSRTPLI--SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-SPVSRRRS 1923
Query: 1177 TTQTPRAGSSSRARSRAPGPR 1197
++TP + R+RSR P R
Sbjct: 1924 RSRTPPV-TRRRSRSRTPTTR 1943
Score = 69.7 bits (169), Expect = 2e-11
Identities = 146/659 (22%), Positives = 223/659 (33%), Gaps = 95/659 (14%)
Query: 641 SPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR 700
S G S++R P PE ++QPS + ++ D S S G EP
Sbjct: 311 SEPGTTSTQR--PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP----- 363
Query: 701 RSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP 760
P P + R G P P + LS++P+ P + + P
Sbjct: 364 --PAPTPLLAE-----RHGGSPQPLA--------TTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 761 PARDGVYVSANGRMVIQLRPGRSPEPDGPAPA---FLRQESFTKEPASGPPAPGKPPHIS 817
P + L S E P+P R S + E PAPG IS
Sbjct: 409 PEK--------------LPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 818 SHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPE 877
S P ++ + RA R HS + + + A R S S G S R P+
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR--SRSRTPTKRGHSRSRSPQ 512
Query: 878 DALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQS 937
S + R G+S P R + SP P T +
Sbjct: 513 WRRSRSAQ---------RWGRS------RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSA 557
Query: 938 SERQHHPLGPTDMGRGEPVRRSAIRRGH-RPRGSLDWPSEERGPVLAHLPSSDVMASNHE 996
+ H P GR R+ RRG R R S R P S
Sbjct: 558 RRGRSHSRSPATRGRSR--SRTPARRGRSRSRTPARRRSRSRTPTRRR--------SRSR 607
Query: 997 TPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSA-----SSQKGPQALTRSNSLSTPRPT 1051
TP G R + + + SP R +SRS A S + P RS S + R
Sbjct: 608 TPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRG 667
Query: 1052 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRK-RAGSF 1110
R+ AR S + S GR + + R R+ R+GS
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727
Query: 1111 TGTSDPEAAPARTSFSGRSVEL------CCASRKPTMAEARAVSR---KAANTATTTGPR 1161
+ + R S S S E+ SR + ++A SR + + + ++ P+
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 1162 Q----PFSRARSGSARYTSTTQTP----RAGSSSRARSRAPGPRDTDDDEEEPDPYGFIV 1213
Q P R+RSGS++ + ++TP R+ SS + ++ P P P V
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK---V 844
Query: 1214 QTAEIAEIARLSQTLVKDVAILAQ--EIHDVAGDGDTLGSSEPAHSASLSNMPSTPAST 1270
++ ++ + ++ Q + + D + + HS S S+ P +ST
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Score = 59.3 bits (142), Expect = 3e-08
Identities = 201/892 (22%), Positives = 295/892 (33%), Gaps = 167/892 (18%)
Query: 352 FTHSPSGDPKADKRRGPTPADRDRPSVPAP--VQAGGRSSGPQRAG----SLKREKTEER 405
F + DP D + T + S +P V+ G SS + ++ R + ER
Sbjct: 1359 FLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER 1418
Query: 406 LGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS--PAARPSPEKVPPVLPAPLTP- 462
S S +P G SR ++ + LR+ S P+ P + P TP
Sbjct: 1419 SSSAS----SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS 1474
Query: 463 HGTSPV-GPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEE---ARKMI 518
G S P P P P+ ++R + + T E ++ V++ AR +
Sbjct: 1475 RGRSECDSSPEPKALPQTPR-PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
Query: 519 DQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQ 578
Q S EL SA+ P R + D S D R L Q S G++P+ + +
Sbjct: 1534 GQRSRSGSSQELDVKPSAS--PQERSESDSSPDSKAKTRTPLRQRSRS---GSSPEVDSK 1588
Query: 579 GLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSER 638
P R G PE ++ + P +
Sbjct: 1589 SRLSPRR---------------------------SRSGSSPE------VKDKPRAAPRAQ 1615
Query: 639 ADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDS 698
+ S + PE P P L P R S S +S G P E S
Sbjct: 1616 SGSDSSPEPK---APAPRAL----PRR----------SRSGSSSKGRG----PSPEGSSS 1654
Query: 699 RRRSPQEGPTWSRGRRSPRAPGEP-----TP----ASFFIGDQNGDAVLSRKPLAAPGDG 749
SP+ P RR R+ EP TP +S + A LSR+ +A
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 750 EGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGP-- 807
E T +PP R RSP P PA + S + AS P
Sbjct: 1715 E----TRSRTPP-----------------RHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Query: 808 ---------PAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARL 858
P+P KP + TR R S + + + + +
Sbjct: 1754 KTTSRRGRSPSP-KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS------ 1806
Query: 859 LSNSVDAECEGGS-----TPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQK 913
+ V GGS +P E + + S S K S T+P P + +
Sbjct: 1807 -RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865
Query: 914 EMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDW 973
+ + T L+S R S P R R S RR R R S
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSR-----TSPVSRRRSRS-RTSVTRRRSRSRAS--- 1916
Query: 974 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQ 1033
R + P S TP T R SR P S + +R + S+
Sbjct: 1917 -PVSRRRSRSRTPPVTRRRSRSRTP--TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973
Query: 1034 KGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGR-------P 1086
P RS S ++P R SR R + + R S PV R P
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPV----------TRRRSRSRTSPVTRRRSRSRTP 2023
Query: 1087 AAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARA 1146
A + + SR +L PRKR+ S + + + +RT + R +R P R+
Sbjct: 2024 PAIRRRSRSRTPLL--PRKRSRSRSPLAIRRRSRSRTPRTARGKR--SLTRSPPAIRRRS 2079
Query: 1147 VSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRD 1198
S +++ + + P P +R SGS + R SR S +P P D
Sbjct: 2080 ASGSSSDRSRSATP--PATRNHSGSRTPPVALNSSRMSCFSRP-SMSPTPLD 2128
Score = 58.2 bits (139), Expect = 6e-08
Identities = 187/884 (21%), Positives = 284/884 (32%), Gaps = 97/884 (10%)
Query: 345 RKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEE 404
RKK S+ H + K K R PTP + + + RS+ P T
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSK--DKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 405 RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHG 464
S S SR+ +R + + LA R SPA+ E P P T
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAG-------RSPSPASGRRGEGDAP-FSEPGTTST 318
Query: 465 TSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGV 524
P P T P+ P K + ++E + + + E + E ++ + G
Sbjct: 319 QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP--SPERSSTGPEPPAPTPLLAERHG- 375
Query: 525 LESPELSRASSATFRPV-----IRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQG 579
SP+ + + PV RD S + L Q +S +PQ
Sbjct: 376 -GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK---LPQSSSSESSPPSPQPTKVS 431
Query: 580 LPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERA 639
SP K S + S P GR + S PS R
Sbjct: 432 RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS----------HTPSRRM 481
Query: 640 DSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSR 699
P +++R S P++ P S GR P + R
Sbjct: 482 GRSRSPATAKRG-----RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP---QRRGR 533
Query: 700 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPS 759
RSPQ P WSR R + R G A A R P G++ +
Sbjct: 534 SRSPQR-PGWSRSRNTQRR-GRSRSARRGRSHSRSPATRGRSRSRTPA---RRGRSRSRT 588
Query: 760 PPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSH 819
P R + R P R PA R+ S T+ P P S
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA--RRRSRTRSPVRRRSRSRSPARRSG- 645
Query: 820 PLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDA 879
+ + T A R S+ + A R S S G S R P
Sbjct: 646 ---RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR--SRSRTPARRGRSRSRTPRRG 700
Query: 880 LSGDSDV----DTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE 935
S + + S R G+SG S R + S S + + +
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE-------MKKSR 753
Query: 936 QSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNH 995
SS R P R + R ++RR + P + SS A +
Sbjct: 754 ISSRRSRSLSSP----RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR 809
Query: 996 ETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALT----RSNSLSTPRPT 1051
P + R ++PPP ++ +S +SS P+ + R S+++P+
Sbjct: 810 TPPRRS--------RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN 861
Query: 1052 RAS--RLRRARLGDASDTE--AADGERGSLGNPEP----VGRPAAEQAKKLS----RLDI 1099
S RR+ + D E + R S P P + + S ++
Sbjct: 862 EQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921
Query: 1100 LAMPRKRAGSFTGTSDPEAAPARTS-FSGRSVELCCASRKPTMAEARAVSRKAANTATTT 1158
+ PR+R+ S + + P +RT+ RSV C S + R +++ T
Sbjct: 922 IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC--SNVESRLLPRYSHSGSSSPDTKV 979
Query: 1159 GPRQPFSRARSGS-ARYTST-TQTPRAGSSSRARSRAPGPRDTD 1200
P P ++ SGS + Y QTP S S ++S P + D
Sbjct: 980 KPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD 1023
Score = 55.8 bits (133), Expect = 3e-07
Identities = 185/813 (22%), Positives = 269/813 (33%), Gaps = 119/813 (14%)
Query: 602 YSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP------ 655
+S+PG T +R PE + + P P E D +S+ R P P
Sbjct: 310 FSEPGTTST---QRPSSPETAT------KQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 656 PELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR--RSPQEGPTWSRGR 713
PE + P L + P L+ S P P R +SP++ P S
Sbjct: 361 PEPPAPTPL-LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419
Query: 714 RSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGR 773
SP +P +PT S + S KP APG + + + +
Sbjct: 420 SSPPSP-QPTKVS----RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 774 MVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARM 833
R GRS P R + TK S +P S+ + + R R
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 834 DFHSQDTHLILKETETALAALEARL-LSNSVDAECEGGSTPRPPEDALSGDSDVDTASTV 892
+ + T+ + AR S+S G S R P A G S T +
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP--ARRGRSRSRTPARR 592
Query: 893 SLRS-------------GKSGPSPTTPQPLRAQKEMSP-------SPPAAQDPGGTALVS 932
RS + G S + R + SP PA + +
Sbjct: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP 652
Query: 933 AREQSSERQHHPLGPTDMGRGE---PVRRSAIRRGHRP--RGSLDWPSEERGPVLAHLPS 987
AR S + P GR P RRS R P RG S R P S
Sbjct: 653 ARRGRSRSRT----PARRGRSRSRTPARRSGRSRSRTPARRGR----SRSRTPRRGRSRS 704
Query: 988 SDVMA---SNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNS 1044
++ S+ TP+ G S RK + + R +S SS +K + RS S
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKS---RTSQRRSRSNSSPEMKKSRISSRRSRS 761
Query: 1045 LSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPR 1104
LS+PR SRL R S + ++ + P R + Q K SR R
Sbjct: 762 LSSPRSKAKSRLSLRR----SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRR 814
Query: 1105 KRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQ-- 1162
R+ S P+R S S S S P +++ AN + T R+
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP--PRQGSITSPQANEQSVTPQRRSC 872
Query: 1163 ------PFSRARSGSARYTSTTQTPRAGSS-----SRARSRAPGPR---------DTDDD 1202
P ++R+ S S + PR SS S +RS +P P+ +
Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
Query: 1203 EEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSE----PAHSA 1258
P P +T +S + +L + H + DT E +HS
Sbjct: 933 SSSPSPSRVTSRTTP-RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSG 991
Query: 1259 SLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALA---- 1314
S+S P A T P SL+ K P S+D ++ SC +L+
Sbjct: 992 SISPYPKVKAQT----------PPGPSLSGSKSPCPQEKSKD---SLVQSCPGSLSLCAG 1038
Query: 1315 -NKTRPRNREEVIFDNLMLNPVSQLSQAIRENT 1346
+ P +L L SQ S R +T
Sbjct: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
Score = 55.1 bits (131), Expect = 5e-07
Identities = 99/411 (24%), Positives = 138/411 (33%), Gaps = 76/411 (18%)
Query: 371 ADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGS--VGRRS- 427
AD P+ PA AG R+ A SL T + +SRTP P + VG RS
Sbjct: 2285 ADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSA 2344
Query: 428 ------RLAQDFMAQCLRESS-PAARPSPEKVPPVLPAPLTP-----HGTSPVGPP---- 471
+A A L +S +AR +P L +P P + PP
Sbjct: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR 2404
Query: 472 ----TPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLES 527
TPP AP+ ++T R + A + ++ AQD + R + F
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD----QPRSPVPSAFS---- 2456
Query: 528 PELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG 587
+ SR A PV G VA + + AP H + P +
Sbjct: 2457 -DQSRCLIAQTTPV--AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 588 GQKWVSRWASL------------------ADSYSDPGLTEDGLGRRGGEPEG-SLPVRMR 628
G + S A+L + S S + G + EG SLPV+
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 629 RRLPQLPSERADSPAGPESSRRSGPGPP------------------ELDSEQPSRLFGQE 670
L ++PS +PA E+ R P P S S
Sbjct: 2574 VALKRVPS---PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 671 ELDPDSLSDASGSDGGRGPEPGVE-PQD-SRRRSPQEGPTWSRGRRSPRAP 719
S S +S S P P PQ + SP++ P R RSPR P
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Score = 53.5 bits (127), Expect = 1e-06
Identities = 203/917 (22%), Positives = 303/917 (33%), Gaps = 173/917 (18%)
Query: 346 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEER 405
+KRS+S T SP+ ++ R P R R P + RS R + R ++ R
Sbjct: 1849 RKRSRSRT-SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS----RTSPVSRRRSRSR 1903
Query: 406 LGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVL-------PA 458
SR+ A P RSR + + R S + PPV
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
Query: 459 PLTPHG----TSPV---------GPPTP--PPAPTDPQLTKARKQEEDDSLSDAGTYTIE 503
P+T TSP+ P T + T P +T+ R + ++ + +
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP-VTRRRSRSRTSPVTRRRSRSRT 2022
Query: 504 TEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP-VIRGDRDESDDGGVAQRMALLQ 562
A ++ + SP R S + P RG R + +R +
Sbjct: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082
Query: 563 EFASRPLGAAPQA--EHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG--- 617
+ R A P A H G P V+ +S +S P ++ L R
Sbjct: 2083 SSSDRSRSATPPATRNHSGSRTPP-------VALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
Query: 618 -EPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRL----FGQEEL 672
EP GS M L Q D P GP PE ++ L
Sbjct: 2136 LEPLGSSRTPMSV-LQQAGGSMMDGP-GPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193
Query: 673 DPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG-----PTWSRGRR---SPRAPGEPTP 724
P A+G P P S R +P P S S R P PT
Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTA 2253
Query: 725 ASFFIGDQNGDAVLSRKPLAAPG-----DGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 779
+ + D A + LA+P L P+ PA + L
Sbjct: 2254 VN--LADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA-------------VNLA 2298
Query: 780 PGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQD 839
R+P A S T A+ P+ + P P +L R+A
Sbjct: 2299 GARTP---AALAALSLTGSGTPPTAANYPSSSRTPQA---PASANLVGPRSAHAT----- 2347
Query: 840 THLILKETETALAALEARLLSNSVDAECEGGS--TPRPPEDALSGDSDVDTASTVSLRSG 897
+ + + TA A A L S + G + +PR P A S S L
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG--RTSPPLLDRA 2405
Query: 898 KSGPSPTTPQPLRAQKEMSPSP-------------PAAQDPGGTALVSAREQSSE---RQ 941
+S P+ P R E +PSP P AQD + + SA S Q
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
Query: 942 HHPL-GPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEA 1000
P+ G + G ++ H S+ P +P SDV E P +
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG---------VPHSDV----GEPPAS 2512
Query: 1001 TGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRAR 1060
TGA ++P+A A+E +S SS+SS + + S+S S+
Sbjct: 2513 TGA------QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSS------------- 2553
Query: 1061 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1120
+S + ++D E SL PV A KR S P AP
Sbjct: 2554 --SSSGSSSSDSEGSSL----PVQPEVA---------------LKRVPS------PTPAP 2586
Query: 1121 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQT 1180
GR E A RK R S ++++++++ S + S S+ +S++ +
Sbjct: 2587 KEAVREGRPPEPTPAKRK------RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1181 PRAGSSSRARSRAPGPR 1197
+ SSS PGP+
Sbjct: 2641 SSSSSSSSPSPAKPGPQ 2657
Score = 51.6 bits (122), Expect = 6e-06
Identities = 251/1237 (20%), Positives = 397/1237 (32%), Gaps = 171/1237 (13%)
Query: 60 RSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDG-----STLPDA 114
RS + PE C + R G + RTPL GQ S G S P
Sbjct: 1498 RSPSSPELNNKC-LTPQRERSGSESSVDQKTVARTPL-GQRSRSGSSQELDVKPSASPQE 1555
Query: 115 QRQGEPYPE---RPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQP----- 166
+ + + P+ + + P++Q S RR S K+ P+
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
Query: 167 -----SQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFS 221
S P+ PA + + +G S + E P K + ++ S
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 222 LRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKG 281
P K TP S+ ++ P L + S S +RT
Sbjct: 1676 ---PEPKTKSRTPPRRRSS---------RSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 282 HKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDE 341
H+ S +P K+ S+ AS + + + R P Q E
Sbjct: 1724 HRRSPSVSSP--EPAEKSRSSRR-RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREK 401
T +R SG ++ RR R R + +G S P R S R
Sbjct: 1781 KTRTTRRRDR-----SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES-SRTS 1834
Query: 402 TEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLT 461
+ R G SRTP P RSR + + +SPA P++ +
Sbjct: 1835 SRRRRGR----SRTP--PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 462 PHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQV 521
TSPV + + +T+ R + +S + + T +R +
Sbjct: 1889 RSRTSPVSRRR---SRSRTSVTRRRSRSRASPVSRRRSRS-RTPPVTRRRSRSRTPTTRR 1944
Query: 522 FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP 581
+P ++R S + P + R S + +R ++ + P
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR----------------RSRSRTSP 1988
Query: 582 VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADS 641
V ++ SR + + S + R ++ R R R P LP +R+ S
Sbjct: 1989 VTR----RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044
Query: 642 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRR 701
+ RRS P + S + S S +S SD R P S R
Sbjct: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS-SDRSRSATPPATRNHSGSR 2103
Query: 702 SPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 761
+P SR R PTP L R +PG E LG + P
Sbjct: 2104 TPPVALNSSRMSCFSRPSMSPTP-------------LDR--CRSPGMLEPLGSSRTPMSV 2148
Query: 762 ARD--GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPP---APGKPPHI 816
+ G + G + + PE + L + + A PP A G +
Sbjct: 2149 LQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARM 2208
Query: 817 SSHP---------------LLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSN 861
S P L + A AA M+ S T I TA+ ++R +
Sbjct: 2209 SQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI----PTAVNLADSRTPAA 2264
Query: 862 SVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPA 921
+ T P D TA V+L ++ P L +P P A
Sbjct: 2265 AAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGART---PAALAALSLTGSGTP-PTA 2320
Query: 922 AQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPV 981
A P S+R + + +GP PV + R S P
Sbjct: 2321 ANYPS-----SSRTPQAPASANLVGPRSAHATAPVNIAGSRTA-AALAPASLTSARMAPA 2374
Query: 982 L--AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA-AREEQSRSSASSQKGPQA 1038
L A+L S V S +E + L R + PP +P+ +R R+ + S + QA
Sbjct: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
Query: 1039 LTRS------NSLSTPRPTRASRLRRARLGD---------------ASDTEAADGERGSL 1077
++S + +P P+ S R + A+ T +A G L
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494
Query: 1078 GNPEP------VGRPAAEQ-AKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSV 1130
P P VG P A A++ S L L ++R S + +S ++ + +S S S
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
Query: 1131 ELCCASR-------------------KPTMAEARAVSRKAANTATTTGPRQPFSRARSGS 1171
+S PT A AV T ++ S + S S
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614
Query: 1172 ARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDP 1208
+ +S++ + + SSS + S + + P P
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Score = 51.2 bits (121), Expect = 7e-06
Identities = 262/1288 (20%), Positives = 404/1288 (31%), Gaps = 247/1288 (19%)
Query: 75 NPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPYPER--------PK 126
+P PE+ P A TPL + +T P +Q P E PK
Sbjct: 351 SPSPERSSTGPEPPAP---TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 127 GPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTKDAEAGG 186
P + +P PQ R S K P P E+ + PT + G
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS--PTSKNRSHG 465
Query: 187 GGAAPVVQSHASFTIEFDDCSP-----GKMKIKDHITKFSLRQRRPPGKEATPGEMVSAE 241
SH SP G+ + + + R R P + + +
Sbjct: 466 RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 242 TKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQ--SDSEDPLAKA 299
P R G R++ + R + H T+ S S P +
Sbjct: 526 RSPQRRGRSRSPQ---RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582
Query: 300 ASAAGVPLEA-------------SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRK 346
S + P S R R R P ++ V +P +
Sbjct: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
Query: 347 KRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSG--PQRAGSLKREKTEE 404
+ +S + +P+ + + R TPA R R P + GRS P R G R +T
Sbjct: 643 RSGRSRSRTPA---RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR-SRSRTPR 698
Query: 405 RLGSPSPA--------SRTPARP--FGSVGRRSRLAQDFMAQCLRESSPAARPSP----- 449
R S S + SRTP R GS R ++ + SSP + S
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Query: 450 --------EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYT 501
K L + G+SP P T R+ S A + T
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSP--------CPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 502 IETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALL 561
++ + ++ ++P SS++ P ++ G R +
Sbjct: 811 PPRRSRSSSSPPPKQKS-------KTPSRQSHSSSSPHPKVKS--------GTPPRQGSI 855
Query: 562 QEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEG 621
+PQA Q + + S +S DP L R G
Sbjct: 856 ---------TSPQANEQSV-----------TPQRRSCFESSPDPELKSRTPSRHSCS--G 893
Query: 622 SLPVRMRRRLP--QLPSERAD---------SPAGPESSRRSGPGPPELDSEQPSRLFGQE 670
S P R++ P Q PS + SP S S P P + S R
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR--SR 951
Query: 671 ELDPDS-----LSDASGSDGGRGPEPGVEPQDSRRRSPQ--------------EGPTWSR 711
+ P S L G P+ V+P+ R+S GP+ S
Sbjct: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS- 1010
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG--------LGQTAQPSPPAR 763
G +SP P E + S + G L ++ GE L +Q SP R
Sbjct: 1011 GSKSP-CPQEKSKDSL-VQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 764 DGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQ 823
+ + +S P R S E AS P S+ P+L+
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 824 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPP--EDALS 881
+ +R S + + + LE + + +T PP +D S
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188
Query: 882 G-------DSDV---DTASTVSLRSGKSGPSPTTPQ-----PLRAQ-KEMSPSPPAAQDP 925
+S + DT T +G SP T + P +Q +E+ +++P
Sbjct: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP 1248
Query: 926 GGTAL-----------VSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWP 974
G L S E S E + P + + + ++++ P + W
Sbjct: 1249 AGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQS--QASLEAVEVPSMASSWG 1306
Query: 975 SEERGPVLAHLPSSDVMASNHETP-EATGAGRLGSRRKPA-----------------APP 1016
P L +S + ++ +P E +G LG+
Sbjct: 1307 GPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETD 1366
Query: 1017 PSPAAREEQSRSS--ASSQKGPQALTRSN-----SLSTPRPTRASRL-RRARLGDASDTE 1068
PS +E+ +RSS +SS+ P A+ ++ S+S+P R R R AS E
Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 1069 AADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGR 1128
DG P R R R+GS G D P+R S SG
Sbjct: 1427 MKDGL------PRTPSR------------------RSRSGSSPGLRDGSGTPSRHSLSGS 1462
Query: 1129 SVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTS----TTQTPRAG 1184
S + R P+ + S P+ P R+RS S+ + T Q R+G
Sbjct: 1463 SPGMKDIPRTPSRGRSECDSSPEPKAL----PQTPRPRSRSPSSPELNNKCLTPQRERSG 1518
Query: 1185 SSS----RARSRAP-GPRDTDDDEEEPD 1207
S S + +R P G R +E D
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELD 1546
Score = 50.4 bits (119), Expect = 1e-05
Identities = 200/908 (22%), Positives = 318/908 (35%), Gaps = 147/908 (16%)
Query: 340 DEDTPRKKRSQSFTHSP-----SGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQ-- 392
+E + +R F SP S P G +P R + S P P Q+ RSS PQ
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP-RVKSSTP-PRQSPSRSSSPQPK 918
Query: 393 -RAGSLKREKTEERLGSPSPA---SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPS 448
+A R+++ SPSP+ SRT R SV S + ++ L S + S
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE----SRLLPRYSHSGSSS 974
Query: 449 PE-KVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQ 507
P+ KV P P + G+ P P P SLS + + + +++
Sbjct: 975 PDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP------------SLSGSKSPCPQEKSK 1022
Query: 508 DTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 567
D+ V+ + GV S + ++G S D R
Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD--------------HR 1068
Query: 568 PLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRM 627
++P+ P + S + P +GG S PV
Sbjct: 1069 SDTSSPEVRQSHSESPSLQ------------SKSQTSP---------KGGRSRSSSPVTE 1107
Query: 628 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGR 687
+ +R + A P P S+ S +D +SL S +
Sbjct: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS----YPTVDSNSLLGQSRLETAE 1163
Query: 688 GPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 747
E P PQE T S PR + +P F + D+ +++ + L P
Sbjct: 1164 SKEKMALP-------PQEDATAS----PPRQKDKFSP--FPVQDRPESSLVFKDTLRTP- 1209
Query: 748 DGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLR---QESFTKEPA 804
E G + P ++ +++ + +S EP G + L +E T
Sbjct: 1210 PRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE 1269
Query: 805 SGPPAPGKPPHISSHPLLQDLAATRAARMDF-------------HSQDTHLILKETETAL 851
S P +P + Q A+ A + H + ++ L+E
Sbjct: 1270 SSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
Query: 852 AALEARLLSNSVDAECEGGSTPRPPEDALSGD--SDVDTASTVSLR---SGKSGPSPTTP 906
+ LE R S + E G + ED L+G + ++T ++ ++ + SG S +
Sbjct: 1329 SPLEFRN-SGPLGTEMNTGFSSEVKED-LNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL 1386
Query: 907 QPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHR 966
P +K S + P A+ R S ER P +M G P S R
Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAV--PRTPSRERSSSASSP-EMKDGLPRTPSRRSRSGS 1443
Query: 967 PRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQS 1026
G D L+ SS M TP + G S +P A P +P R S
Sbjct: 1444 SPGLRDGSGTPSRHSLSG--SSPGMKDIPRTP-SRGRSECDSSPEPKALPQTPRPR---S 1497
Query: 1027 RSSASSQKGPQALT----RSNSLSTPRPTRASRL---RRARLGDASDTEAADGERGSLGN 1079
RS +S + + LT RS S S+ +R +R+R G + + + + S
Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV----KPSASP 1553
Query: 1080 PEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKP 1139
E ++ +K +R + R R+GS R S SG S E+ KP
Sbjct: 1554 QERSESDSSPDSKAKTRTPL--RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV---KDKP 1608
Query: 1140 TMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAP-GPRD 1198
RA R + + ++ P+ P RA + R+GSSS+ R +P G
Sbjct: 1609 -----RAAPRAQSGSDSSPEPKAPAPRA---------LPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 1199 TDDDEEEP 1206
T+ E P
Sbjct: 1655 TESSPEHP 1662
Score = 49.3 bits (116), Expect = 3e-05
Identities = 180/873 (20%), Positives = 296/873 (33%), Gaps = 111/873 (12%)
Query: 343 TPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 402
TP R +S + +P+ ++ R P R R P + RS R + R ++
Sbjct: 1927 TPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS----RTSPITRRRS 1982
Query: 403 EERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLP----- 457
R SP R+ +R RRSR R S R S + PP +
Sbjct: 1983 RSRT-SPVTRRRSRSRTSPVTRRRSRS---------RTSPVTRRRSRSRTPPAIRRRSRS 2032
Query: 458 -APLTPHGTSPVGPP----------TPPPAPTDPQLTKA----RKQEEDDSLSDAGTYTI 502
PL P S P TP A LT++ R++ S SD
Sbjct: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
Query: 503 ETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDD-----GGVAQR 557
++ + L S +S S + P DR S G
Sbjct: 2093 PPATRNHSGSRTPPV------ALNSSRMSCFSRPSMSPTPL-DRCRSPGMLEPLGSSRTP 2145
Query: 558 MALLQEFASRPL-GAAPQA-EHQGLPVPGSPGGQKWVSRWA--SLADSYSDPGLTEDGLG 613
M++LQ+ + G P+ +HQ VP + + SL + P ++ GL
Sbjct: 2146 MSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLA 2205
Query: 614 RRGGEPEGSLPVRMRRRLP------QLPSERADSPAGPESSRRSGPGPPEL---DSEQPS 664
R + +P+ R P ++P+ A + A +S R+ P + DS P+
Sbjct: 2206 ARMSQVPAPVPLMSLRTAPAANLASRIPA--ASAAAMNLASARTPAIPTAVNLADSRTPA 2263
Query: 665 RLFGQEELDPDSLSDASG---SDGGRGPEPGVEPQDSRRRSPQEG---------PTWSRG 712
P + S +D P V +R + PT +
Sbjct: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 713 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 772
S R P P A+ +G ++ A AP + G +TA PA +
Sbjct: 2324 PSSSRTPQAPASANL-VGPRSAHAT-------APVNIAG-SRTAAALAPAS-----LTSA 2369
Query: 773 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHP-LLQDLAATRAA 831
RM L P P A+ R T P PP S + + A + ++
Sbjct: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS 2429
Query: 832 RMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTAST 891
RM + L+ + + + + S + +TP +LS + T S+
Sbjct: 2430 RMG-QAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ--TTPVAGSQSLSSGAVATTTSS 2486
Query: 892 VSLRSGK-SGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDM 950
+G S P+P P + P+ AQ P A A + + ER+ +
Sbjct: 2487 AGDHNGMLSVPAPGVPH---SDVGEPPASTGAQQPSALA---ALQPAKERRSSSSSSSSS 2540
Query: 951 GRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRR 1010
S+ S S+ G L P + TP A R G
Sbjct: 2541 SSSSSSSSSSSSSSSSGSSS----SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR-- 2594
Query: 1011 KPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA 1070
P P+PA R+ +S SS+SS + + S+S S+ + +S + +S + +
Sbjct: 2595 ---PPEPTPAKRKRRSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 1071 DGERGSLGNPEPVG---RPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSG 1127
+ G P+P P E+ + R I ++ R+ S++ +P +
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 1128 RSVELCCASRKPTMAEARAVSRKAANTATTTGP 1160
+S SR+ ++R+ S K + P
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 48.1 bits (113), Expect = 6e-05
Identities = 95/439 (21%), Positives = 154/439 (35%), Gaps = 46/439 (10%)
Query: 779 RPGRSPEPDGPAP-AFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 837
R + P P+ P P + +R+ S ++ P P K + ++ R R
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPT---PKQKKKKKKKDRGRRSESSSPRRERKKSSK 214
Query: 838 QDTHLILKETETAL---AALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSL 894
+ H E++ +++ S + +TP P + D+AS+
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 895 RSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGE 954
+S S A SPSP + + G A S E + P P
Sbjct: 275 SRSRSR-SAAAKTHTTALAGRSPSPASGRRGEGDAPFS--EPGTTSTQRPSSP------- 324
Query: 955 PVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATG--AGRLGSRRKP 1012
+A ++ P D +E+ PS + ++ E P T A R G +P
Sbjct: 325 ---ETATKQPSSPYEDKDKDKKEKSATRPS-PSPERSSTGPEPPAPTPLLAERHGGSPQP 380
Query: 1013 AAP---------PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGD 1063
A PPS A+ S +K PQ+ + +S +P+PT+ SR +
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 1064 ASDTEAADGERGSLGNPEPVGRP--AAEQAKKLSRLDILAMPRKR--AGSFTGTSDPEAA 1119
A R +P R A++ K S M R R A + G S
Sbjct: 441 PKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP 500
Query: 1120 PARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQP-FSRARSGSARYTSTT 1178
R RS + R+ A+ SR + P++P +SR+R+ R S
Sbjct: 501 TKRGHSRSRSPQW----RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS-- 554
Query: 1179 QTPRAGSSSRARSRAPGPR 1197
R+ R+ SR+P R
Sbjct: 555 ---RSARRGRSHSRSPATR 570
Score = 44.7 bits (104), Expect = 7e-04
Identities = 147/729 (20%), Positives = 237/729 (32%), Gaps = 121/729 (16%)
Query: 343 TPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 402
T R ++ T PS P DK + RPS P+P ++ S+GP+
Sbjct: 318 TQRPSSPETATKQPSS-PYEDKDKDKKEKSATRPS-PSPERS---STGPEPPAPTPL-LA 371
Query: 403 EERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTP 462
E GSP P + TP ++Q A P+ ++ PP P L
Sbjct: 372 ERHGGSPQPLATTP-----------------LSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 463 HGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVF 522
+S PP+P P + + E G++
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSS--PESPKPAPAPGSHR--------------------- 451
Query: 523 GVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAA-----PQAEH 577
E+S + ++ R R RD+S ++RM + A+ G + + H
Sbjct: 452 ------EISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505
Query: 578 QGLPVP---GSPGGQKW----VSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRR 630
P S Q+W + + S PG + +R G + R R
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Query: 631 LPQLPS-ERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP 689
P R+ +PA SR P S P+R + + + GR
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR---------TPARRGRSR 616
Query: 690 EPGVEPQDSRRRSPQEGPTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 747
+ SR RSP + SR RRS R+ TPA A R P
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR-TPARRGRSRSRTPARRGRSRSRTPA 675
Query: 748 DGEGLGQTAQPSPPARDGVYVSANGRMVIQ--LRPGRSPEPDGPAPAFLRQESFTKEPAS 805
G ++ P+ R GR + +R GRS + + S
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS-----------HSRTPQRRGRS 724
Query: 806 GPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDA 865
G + K +S + ++ + S+ + + A + L R S S +
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR-RSLSGSS 783
Query: 866 ECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDP 925
C + PP + SG S S R +S SP QK +PS
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP-----KQKSKTPS------- 831
Query: 926 GGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHL 985
R+ S HP + G P R+ +I P+ + + +R
Sbjct: 832 --------RQSHSSSSPHP----KVKSGTPPRQGSIT---SPQANEQSVTPQRRSCFESS 876
Query: 986 PSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSL 1045
P ++ + +G+ R K + PP +R + + P+ + S S
Sbjct: 877 PDPELKSRTPSRHSCSGSS--PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS- 933
Query: 1046 STPRPTRAS 1054
S+P P+R +
Sbjct: 934 SSPSPSRVT 942
Score = 43.1 bits (100), Expect = 0.002
Identities = 99/448 (22%), Positives = 141/448 (31%), Gaps = 93/448 (20%)
Query: 614 RRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELD 673
R G L R R R P P+ P SR + P PS GQ
Sbjct: 2392 RVSGRTSPPLLDRARSRTP---------PSAPSQSRMTSERAPS-----PSSRMGQA--- 2434
Query: 674 PDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQN 733
P D R P P SR Q P S A T ++ GD N
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA---GDHN 2491
Query: 734 GDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAF 793
G L+ P G +P PA G + + + RS + +
Sbjct: 2492 G-------MLSVPAPGVPHSDVGEP--PASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
Query: 794 LRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAA 853
S + +S + SS P+ ++A R ++ + E A
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602
Query: 854 LEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQK 913
+ R S+S + S+ + S S ++S+ S S S PSP P P K
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SSSSSSPSPAKPGPQALPK 2661
Query: 914 EMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDW 973
SP P PG RR PR +D
Sbjct: 2662 PASPKKP---PPGE----------------------------------RRSRSPRKPIDS 2684
Query: 974 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSS-ASS 1032
+ R L++ P RR+P+ P P+ R++QS SS S
Sbjct: 2685 LRDSRS--LSYSPV--------------------ERRRPS---PQPSPRDQQSSSSERGS 2719
Query: 1033 QKGPQALTRSNSLSTPRPTRASRLRRAR 1060
++G + +RS S R T + R R R
Sbjct: 2720 RRGQRGDSRSPSHKRRRETPSPRPMRHR 2747
Score = 42.7 bits (99), Expect = 0.003
Identities = 69/316 (21%), Positives = 120/316 (37%), Gaps = 31/316 (9%)
Query: 1005 RLGSRRKPAAPPPSPAAREEQSRSSAS------SQKGPQALTRSNSLSTPRPTRASRLRR 1058
R ++PA PP P + +S SS S +K + R + S+PR R ++
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
Query: 1059 ARLGDASDTEAADGERGSLGNPEPVG-RPAAEQAKKLSRLDILAMPRKRAGSFT-----G 1112
+ S++E+ + S P P R + ++ +K SR A +RA T
Sbjct: 216 KK--HRSESESKKRKHRS---PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 1113 TSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKA----ANTATTTGPRQPFSRAR 1168
+SD + +R S + ++ A R P+ A R A T +T P P + +
Sbjct: 271 SSDTSRSRSR-SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
Query: 1169 SGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTL 1228
S+ Y + + S++R +P P + E P P T +AE S
Sbjct: 330 QPSSPYEDKDKDKKEKSATRP---SPSPERSSTGPEPPAP------TPLLAERHGGSPQP 380
Query: 1229 VKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNF 1288
+ + + ++ + T S P L S+ +S S + V R +S
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 1289 QKVPPGSLNSRDFDQN 1304
K P + R+ +
Sbjct: 441 PKPAPAPGSHREISSS 456
Score = 32.0 bits (71), Expect = 4.6
Identities = 56/270 (20%), Positives = 86/270 (31%), Gaps = 67/270 (24%)
Query: 253 PSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEASGE 312
PS L + P +R S+ S + S S + ++ ++ E S
Sbjct: 2518 PSALAALQPAKERRSSSSS---------SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 313 QVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPAD 372
V+ + +KR P TP K + P P KRR + +
Sbjct: 2569 PVQPEVALKRVPSP----------------TPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
Query: 373 RDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQD 432
S + + SS + S + SPSPA P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP---------------- 2656
Query: 433 FMAQCLRESSPAARPSPEKVPPVLPAPLTPH------------GTSPV--GPPTPPPAPT 478
Q L + + SP+K PP +P SPV P+P P+P
Sbjct: 2657 ---QALPKPA-----SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 479 DPQLTK----ARKQEEDDSLSDAGTYTIET 504
D Q + +R+ + DS S + ET
Sbjct: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRET 2738
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 67.8 bits (164), Expect = 8e-11
Identities = 203/909 (22%), Positives = 292/909 (32%), Gaps = 173/909 (19%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGV-PLEASGEQVRLQRQ--------IKRDPQELLHNQQA 333
K +DG + + DP+ + V P + G++ R+ + + +L +
Sbjct: 1533 KFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDL 1592
Query: 334 FVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRP-SVPAPVQAGGRSSGPQ 392
+ E R K+ + H SGDPK ++ P R + +PA P
Sbjct: 1593 EIEERHKRHKERMKQMEKLRHR-SGDPKLKEKAKPADDGRKKGLDIPA-------KKPPG 1644
Query: 393 RAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKV 452
K +K +E P PA+ P + LA M +
Sbjct: 1645 LDPPFKDKKLKESTPIP-PAAENKLHPASGADSKDWLAGPHMKE---------------- 1687
Query: 453 PPVLPAPLTPHGTSPVGPPTPPPAPT---------DPQLTKARKQEEDDSLSDAGTYTIE 503
VLPA P + P G PTP + P+ + D + D
Sbjct: 1688 --VLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHS 1745
Query: 504 TEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP------------VIRGDRDESDD 551
T F V S AS A RP + R +E
Sbjct: 1746 TPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLSTNLYRSVSVDIRRTPEEEFSV 1805
Query: 552 GGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDP--GLTE 609
G R + +S P E + P+P P ++A L+ Y P GL
Sbjct: 1806 GDKLFRQQSVPAASSYDSPMPPSMEDRA-PLPPVP-----AEKFACLSPGYYSPDYGLPS 1859
Query: 610 DGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP-PELDSEQPSRLFG 668
+ P + V SP G SS ++ P P P + PS L G
Sbjct: 1860 PKVDALHCPPAAVVTV-------------TPSPEGVFSSLQAKPSPSPRAELLVPS-LEG 1905
Query: 669 QEELDPDSLSDASGSDGGRGPEPG-VEPQDSRRRSPQEGPTWSRGRRSP---RAPGEPTP 724
D D+ D + PEP +EP D EGP + P P E
Sbjct: 1906 ALPPDLDTSEDQQATAAIIPPEPSYLEPLD-------EGPFSAVITEEPVEWAHPSEQAL 1958
Query: 725 ASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQ--PSPPAR----DGVYVSANGRMVIQL 778
AS IG S P++ P + L ++ Q P P R D ++ +A G
Sbjct: 1959 ASSLIGG------TSENPVSWPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASE 2012
Query: 779 RPGRSPEPDGPAPAFLR---------QESFTKEPA---SGPPAPGKPPHISSHPLLQDLA 826
P +P P PAP L ++ PA + AP PP +
Sbjct: 2013 APYPAP-PASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPS-GLESFFSNCK 2070
Query: 827 ATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDV 886
+ A +D + + AL LE L S G P P DA +G D
Sbjct: 2071 SLPEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDD 2130
Query: 887 DTASTVSL-------RSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE---- 935
SL + G + + L +EM P P + G + V A E
Sbjct: 2131 LDLGPFSLPELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPPAL 2190
Query: 936 ---QSSER-----QHHPLG-----------------PTDMGRGEP---VRRSAIRRGHRP 967
Q+S R + P G P + RG+P V + + RP
Sbjct: 2191 PPDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEERARGDPDSSVEPAPVPPEQRP 2250
Query: 968 RGSLDWPSEERGPVLAHLPSSDVMASN--HETPEATGAG-----RLGSRRKPAAPPPSPA 1020
GS D +E GP A L + D A N + A GAG PA PP
Sbjct: 2251 LGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGI 2310
Query: 1021 ARE-EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGN 1079
E + + +A + K P+ P R +R R L + S E+
Sbjct: 2311 QPEAAEPKPTAEAPKAPRV--------EEIPQRMTRNRAQMLANQSKQGPPPSEKECAPT 2362
Query: 1080 PEPVGRPAA 1088
P PV R A
Sbjct: 2363 PAPVTRAKA 2371
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 65.1 bits (157), Expect = 5e-10
Identities = 128/546 (23%), Positives = 189/546 (34%), Gaps = 130/546 (23%)
Query: 745 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPA 804
A + E G+T P A G+ V L G+SP A S T+E
Sbjct: 125 AKAETEKAGKTGNSMPHP-------ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG 177
Query: 805 SGPP--APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 862
S P A KP +S A + D S+DT ET+ + A E L +
Sbjct: 178 SVPAFGAAAKPGMVS------------AGQADSSSEDTSSSSDETDVEVKASEKILQVRA 225
Query: 863 VDAECEG----GSTPRPPEDA---------------------LSGDSDVDTASTVSL--- 894
A +G G+TP PP A S DS+ +T + +L
Sbjct: 226 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 285
Query: 895 -RSGKSGP--SPTTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQH 942
SGK+ + + P +K +P+PP P S+ E+S +
Sbjct: 286 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 345
Query: 943 HPLGPTDMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET 997
P G+ VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 346 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
Query: 998 -------------------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----E 1023
P +T G G LG P P P +P+A+ E
Sbjct: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465
Query: 1024 EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPV 1083
E S SS+ S+S PT + + LG+ +A + G P+
Sbjct: 466 EDSESSSEES--------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKA 515
Query: 1084 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM-- 1141
G P A Q K +D + + S +D E APA + A KP +
Sbjct: 516 G-PVAVQVKAEKPMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKI 561
Query: 1142 AEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDD 1201
+ +A +K T TT + R + + R T +P AGSS P +
Sbjct: 562 PQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSS 617
Query: 1202 DEEEPD 1207
EE D
Sbjct: 618 SSEESD 623
Score = 65.1 bits (157), Expect = 5e-10
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 124/876 (14%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 341
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 375
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 397
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 398 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 452
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Query: 453 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 502
P PA P PV P D + + DS T
Sbjct: 496 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 555
Query: 503 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 543
+T+A + T + K+ G + A+S T RP
Sbjct: 556 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 615
Query: 544 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 595
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
Query: 596 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 653
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 676 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 711
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 733 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 771
G + E + +G R LA + G A P+PP + G +
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 849
Query: 772 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 830
G+ + DG APA + K P P ++ P A+T R
Sbjct: 850 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 831 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 889
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 890 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 949
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 970 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1011
Query: 950 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1009
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1012 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1048
Query: 1010 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1058
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVE 1108
Query: 1059 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1093
++S+ + + L G P PA QA K
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1144
Score = 59.7 bits (143), Expect = 2e-08
Identities = 209/1025 (20%), Positives = 350/1025 (34%), Gaps = 221/1025 (21%)
Query: 340 DEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDRPSVPAPVQAGGRSS 389
+E+TP K S + S K R+G P P + P+V A QAG R
Sbjct: 273 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV-AKAQAGKREE 331
Query: 390 GPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP 449
Q + S + + EE P+ + P +R +S A+ SP
Sbjct: 332 DSQ-SSSEESDSEEEAPAQAKPSGKAPQ--------------------VRAASAPAKESP 370
Query: 450 EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDT 509
K G +P P PA Q+ KQEED S +E D+
Sbjct: 371 RK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS--------SEESDS 407
Query: 510 EVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRP 568
+ E M QV + +SP++ AS+ P+ +G
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG------------------------ 443
Query: 569 LGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMR 628
G P G P +P Q V +W ++S S+ E G P P + +
Sbjct: 444 AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSSDGEVPTAVAPAQEK 493
Query: 629 RRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------SRLFGQEELDPDSLS 678
L ++ SPA GP +++GP ++ +E+P S E P +++
Sbjct: 494 SLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551
Query: 679 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT--------------- 723
A + P+ P+ + + + G ++PR G T
Sbjct: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611
Query: 724 PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQL 778
PA + D+ + LA A G+GL Q S P + + G+ +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSL-----GQGTAPV 665
Query: 779 RPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 837
PG++ A +++S ++E + A P + + A AA +
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 838 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 897
+ T + ++++ + A+ S +PP STV R
Sbjct: 726 KGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-------STVLARGP 767
Query: 898 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPT-DMGRGEPV 956
S PS AQ + P +D G S E SE + L G+ +
Sbjct: 768 ASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAETLAQVKPSGKTHQI 819
Query: 957 RRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP 1015
R + PR G+ P + GP A D S+ E ++ G
Sbjct: 820 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 1016 PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRARLGDASDTEAADGER 1074
P P + +RS A P ++ + STPR RAS R+ ++ D +
Sbjct: 880 P--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESEDEDVI---- 930
Query: 1075 GSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSDPEAAPARTSFSGRS 1129
PA + R +++ MP S G S + + + +
Sbjct: 931 -----------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
Query: 1130 VELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS--GSARYTS--TTQ 1179
S+K T A + +++KA+ QP S S G+ TS +T
Sbjct: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
Query: 1180 TPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLV--- 1229
G++ + + P P +DD E+ D + E + A+ + TLV
Sbjct: 1040 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPT 1099
Query: 1230 -KDVAILAQEIHDVAGDGDTLGSSE------------PAHSASLSNMP---STP--ASTI 1271
L +E + + D + S+ PA+S + P S+P +ST+
Sbjct: 1100 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1159
Query: 1272 SAREE 1276
+A+++
Sbjct: 1160 AAKDD 1164
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 65.1 bits (157), Expect = 5e-10
Identities = 128/546 (23%), Positives = 189/546 (34%), Gaps = 130/546 (23%)
Query: 745 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPA 804
A + E G+T P A G+ V L G+SP A S T+E
Sbjct: 125 AKAETEKAGKTGNSMPHP-------ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG 177
Query: 805 SGPP--APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 862
S P A KP +S A + D S+DT ET+ + A E L +
Sbjct: 178 SVPAFGAAAKPGMVS------------AGQADSSSEDTSSSSDETDVEVKASEKILQVRA 225
Query: 863 VDAECEG----GSTPRPPEDA---------------------LSGDSDVDTASTVSL--- 894
A +G G+TP PP A S DS+ +T + +L
Sbjct: 226 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 285
Query: 895 -RSGKSGP--SPTTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQH 942
SGK+ + + P +K +P+PP P S+ E+S +
Sbjct: 286 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 345
Query: 943 HPLGPTDMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET 997
P G+ VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 346 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
Query: 998 -------------------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----E 1023
P +T G G LG P P P +P+A+ E
Sbjct: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465
Query: 1024 EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPV 1083
E S SS+ S+S PT + + LG+ +A + G P+
Sbjct: 466 EDSESSSEES--------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKA 515
Query: 1084 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM-- 1141
G P A Q K +D + + S +D E APA + A KP +
Sbjct: 516 G-PVAVQVKAEKPMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKI 561
Query: 1142 AEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDD 1201
+ +A +K T TT + R + + R T +P AGSS P +
Sbjct: 562 PQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSS 617
Query: 1202 DEEEPD 1207
EE D
Sbjct: 618 SSEESD 623
Score = 62.0 bits (149), Expect = 4e-09
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 125/876 (14%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 341
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 375
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 397
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 398 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 452
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Query: 453 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 502
P PA P PV P D + + DS T
Sbjct: 496 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 555
Query: 503 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 543
+T+A + T + K+ G + A+S T RP
Sbjct: 556 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 615
Query: 544 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 595
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
Query: 596 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 653
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 676 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 711
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 733 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 771
G + E + +G R LA + G A P+PP + G +
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 849
Query: 772 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 830
G+ + DG APA + K P P ++ P A+T R
Sbjct: 850 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 831 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 889
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 890 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 949
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 970 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1011
Query: 950 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1009
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1012 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1048
Query: 1010 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1058
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETLVE 1107
Query: 1059 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1093
++S+ + + L G P PA QA K
Sbjct: 1108 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1143
Score = 58.5 bits (140), Expect = 5e-08
Identities = 211/1025 (20%), Positives = 352/1025 (34%), Gaps = 222/1025 (21%)
Query: 340 DEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDRPSVPAPVQAGGRSS 389
+E+TP K S + S K R+G P P + P+V A QAG R
Sbjct: 273 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV-AKAQAGKREE 331
Query: 390 GPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP 449
Q + S + + EE P+ + P +R +S A+ SP
Sbjct: 332 DSQ-SSSEESDSEEEAPAQAKPSGKAPQ--------------------VRAASAPAKESP 370
Query: 450 EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDT 509
K G +P P PA Q+ KQEED S +E D+
Sbjct: 371 RK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS--------SEESDS 407
Query: 510 EVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRP 568
+ E M QV + +SP++ AS+ P+ +G
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG------------------------ 443
Query: 569 LGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMR 628
G P G P +P Q V +W ++S S+ E G P P + +
Sbjct: 444 AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSSDGEVPTAVAPAQEK 493
Query: 629 RRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------SRLFGQEELDPDSLS 678
L ++ SPA GP +++GP ++ +E+P S E P +++
Sbjct: 494 SLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551
Query: 679 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT--------------- 723
A + P+ P+ + + + G ++PR G T
Sbjct: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611
Query: 724 PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQL 778
PA + D+ + LA A G+GL Q S P + + G+ +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSL-----GQGTAPV 665
Query: 779 RPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 837
PG++ A +++S ++E + A P + + A AA +
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 838 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 897
+ T + ++++ + A+ S +PP STV R
Sbjct: 726 KGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-------STVLARGP 767
Query: 898 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPT-DMGRGEPV 956
S PS AQ + P +D G S E SE + L G+ +
Sbjct: 768 ASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAETLAQVKPSGKTHQI 819
Query: 957 RRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP 1015
R + PR G+ P + GP A D S+ E ++ G
Sbjct: 820 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 1016 PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRARLGDASDTEAADGER 1074
P P + +RS A P ++ + STPR RAS R+ ++ D +
Sbjct: 880 P--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESEDEDVI---- 930
Query: 1075 GSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSDPEAAPARTSFSGRS 1129
PA + R +++ MP S G S + + + +
Sbjct: 931 -----------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
Query: 1130 VELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS--GSARYTS--TTQ 1179
S+K T A + +++KA+ QP S S G+ TS +T
Sbjct: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
Query: 1180 TPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEIAEIAR--------- 1223
G++ + + P P +DD E+ D + E + A+
Sbjct: 1040 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1099
Query: 1224 -LSQTLVKDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSNMP---STP--ASTI 1271
++TLV++ A + E DV +L S PA+S + P S+P +ST+
Sbjct: 1100 SRTETLVEETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1158
Query: 1272 SAREE 1276
+A+++
Sbjct: 1159 AAKDD 1163
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 63.2 bits (152), Expect = 2e-09
Identities = 243/1198 (20%), Positives = 407/1198 (33%), Gaps = 237/1198 (19%)
Query: 159 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 215
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 216 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 270
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 271 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 325
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 326 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 375
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 376 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 435
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 436 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 495
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 496 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 554
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 555 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 614
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 615 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 664
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 665 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 723
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 724 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 764
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 823
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 824 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 883
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 884 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 943
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 944 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1001
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1002 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1060
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1061 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1120
++ D + PA + R +++ MP T+ P AP
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMP---------TAHPRIAP 1033
Query: 1121 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFS-RARSGSARYTSTTQ 1179
+ S +G S + +++ + A + G S ++ S A+ T+ +
Sbjct: 1034 -KASMAGAS----SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 1180 TPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLV----KDVAIL 1235
P+ +A P +DD E+ D + E + A+ + TLV L
Sbjct: 1089 KPKLPEVQQA---TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL 1145
Query: 1236 AQEIHDVAGDGDTLGSSE------------PAHSASLSNMP---STP--ASTISAREE 1276
+E + + D + S+ PA+S + P S+P +ST++A+++
Sbjct: 1146 VEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1203
Score = 53.9 bits (128), Expect = 1e-06
Identities = 171/923 (18%), Positives = 296/923 (32%), Gaps = 102/923 (11%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 341
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 397
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 398 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 452
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 453 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 502
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 503 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 543
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 544 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 595
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 596 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 653
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 711
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 771
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 772 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 830
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 831 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 889
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 890 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR-EQSSERQHHPLGPT 948
S +S + GP+ + SP + Q G L + + + P
Sbjct: 1047 SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1106
Query: 949 DMGRGEPVRRSAIRRGHRPRG-----SLDWPSEERGPVL-----AHLPSSDVMA------ 992
D + G P+G +L P+ R L A DV+A
Sbjct: 1107 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1166
Query: 993 SNHETPEATGAGRLGSRRKP-----------AAPPPSPAAREEQSRSSASSQKGPQALTR 1041
S + TP T A S+ P A P ++E A+ P+ +
Sbjct: 1167 SGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1226
Query: 1042 SNSLSTPRPTRASRLRRARLGDASDTEAADGE--RGSLGNPEPVGRPAAEQAKKLSRLDI 1099
+ T P ++ + ++ + T A + LG P P+ + + ++
Sbjct: 1227 EAASGT-TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1285
Query: 1100 LAMPRKRAGSFTGTSDPEAAPAR 1122
L RK+ T S + +R
Sbjct: 1286 LEQERKKVVDTTKESSRKGWESR 1308
Score = 53.5 bits (127), Expect = 1e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 588 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 646
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 647 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 706
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 707 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 764
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 824
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 825 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 870
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 871 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 903
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 904 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 954
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 955 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 997
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 998 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1035
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1036 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1095
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1096 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1153
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1154 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1207
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 63.2 bits (152), Expect = 2e-09
Identities = 177/765 (23%), Positives = 253/765 (33%), Gaps = 164/765 (21%)
Query: 123 ERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTK------------ETPQPSQPP 170
ERP+G +++ APA P R +PS T P+PS+PP
Sbjct: 1540 ERPQG--RKEAPAPSKAAPAAPPPA--RTQPSLIADETPPCYSLSSSASSLSEPEPSEPP 1595
Query: 171 EV-PAHEMP--TKDAEAGGGGAAPVVQSHASFTIE--FDDCSP-------GKMKIKDHIT 218
V P P TKD GGG + A ++ P G + K T
Sbjct: 1596 AVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRAT 1655
Query: 219 KFSLRQR---RPPGKEATPGEMVS------------AETKVADWLVQNDPSLLHRVGPGD 263
+ R R G+EA + S + WL Q + D
Sbjct: 1656 RLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESD 1715
Query: 264 DRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVP-LEASGEQVRLQRQIKR 322
S S L V + TL+ KH G Q++ E A+ G ++ SG +
Sbjct: 1716 SILSFVSGLSVGS-TLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSP-----RSPA 1769
Query: 323 DPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDR------- 375
P++ Q+ P R ++ + PS P+A + P P R
Sbjct: 1770 GPEKPRGTQKT------TPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCL 1823
Query: 376 --PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDF 433
P+ PA V S G QR+ SL R L + S R+ P +RLA+
Sbjct: 1824 AQPAAPAKVP----SPGQQRSRSLHRPAKTSELATLSQPPRSATPP-------ARLAKT- 1871
Query: 434 MAQCLRESSPAARPSPEKVPPVL------------PAPLTPHGT----------SPV--- 468
+ ++SPA++P P K PPV P P TP T SPV
Sbjct: 1872 PSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIP 1931
Query: 469 --------GPP-----TPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETE-AQDTEVEEA 514
GPP P P P T+A L G + + + +E +
Sbjct: 1932 FMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRL---GLVRVASALSSGSESSDR 1988
Query: 515 RKMIDQVFGVLESP-------ELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 567
Q+ + ESP ELS A SA P R G A L
Sbjct: 1989 SGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPR----RGRPALPAVFLCSSRCE 2044
Query: 568 PLGAAPQ----AEHQGLPVPGSPGGQKWVSRWASLADS---YSDPGLTEDGLGRRGGEPE 620
L AAP+ Q P G++ R S + S P + + R P
Sbjct: 2045 ELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYASLPH 2104
Query: 621 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPE---------------LDSEQPSR 665
S+ R +P +PA +++RRS G P D + P
Sbjct: 2105 ISVARRPDGAVPA-------APASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHI 2157
Query: 666 LFGQEELDPDSLSDASGSDGGRGPEP----GVEPQDSRRRSPQEGPTWSRGRRSPRAPGE 721
L L ++ D GP P Q +P+ + S + PG
Sbjct: 2158 LRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGA 2217
Query: 722 PTPASF-FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDG 765
P +G L++ P++AP EGLG P +R G
Sbjct: 2218 PAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHG 2262
Score = 51.2 bits (121), Expect = 7e-06
Identities = 199/874 (22%), Positives = 289/874 (33%), Gaps = 167/874 (19%)
Query: 381 PVQAGGRS-SGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLR 439
P + GG +G AG +RE+ P+P T +RP G+ + L + +CL
Sbjct: 1302 PERGGGAGGAGLHFAGHRRREE------GPAP---TGSRPRGAADQELEL----LRECLG 1348
Query: 440 ESSPAA--RPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDA 497
+ PA + + VP P+ PV P PAP +EDDS +D+
Sbjct: 1349 AAVPARLRKVASALVPGRRALPV------PVYMLVPAPAPA----------QEDDSCTDS 1392
Query: 498 GTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQR 557
E A + D+ L+ P RD+ GG A R
Sbjct: 1393 A------EGTPVNFSSAASLSDET---LQGPP----------------RDQP--GGPAGR 1425
Query: 558 MALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG 617
Q RP A H+ G G SR A + GL E LGR
Sbjct: 1426 ----QRPTGRPTSARQAMGHRHKA--GGAGRSAEQSRGAGK----NRAGL-ELPLGRPPS 1474
Query: 618 EP---EGSLPVRMRR--RLPQL----PSERA-------DSPAGPESSRRSGPGPPELDSE 661
P +GS P R R L L P+E A DS P ++ P P +
Sbjct: 1475 APADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA---APTPTHRRTS 1531
Query: 662 QPSRLFGQEELDPDSLSDASGSDGGRGPEPG-VEPQDSRRRSPQEGPTWSRGRRSPRAPG 720
R F +E + A P P +P +P P +S S +
Sbjct: 1532 AIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETP---PCYSLSS-SASSLS 1587
Query: 721 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
EP P+ G R+P G G G+ + PSP A + + R + P
Sbjct: 1588 EPEPSEPPAVHPRG-----REPAVTKDPGPGGGRDSSPSPRAAEELLQ----RCISSALP 1638
Query: 781 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 840
R P G R + PA G G+ S D RA + +S T
Sbjct: 1639 RRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVT 1698
Query: 841 HLILKETETALAALEARLLSNSVDAECEG---GSTPRPPEDALSGDSDVDTAST------ 891
L + A A EA S+S+ + G GST +PP+ ++ + S
Sbjct: 1699 WL----HQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKR 1754
Query: 892 --VSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 949
S+++ S SP P+ R ++ +P PA V + P
Sbjct: 1755 GAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSP-----------APRA 1803
Query: 950 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1009
+G P R+ R+ P ++ P P S H + + L
Sbjct: 1804 QPKGTPGPRATPRKVAPP-----CLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQP 1858
Query: 1010 RKPAAPPPSPAAREEQSRSSASSQKGPQ----------------ALTRSNSLSTPRPTRA 1053
+ A PP AR ++ SS+SSQ P AL + P+
Sbjct: 1859 PRSATPP----ARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPAR 1914
Query: 1054 SRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGT 1113
+ L + S +R + P P+ R E + R A P R G
Sbjct: 1915 TLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPR-GRAGTEAGPGARGGRLGLV 1973
Query: 1114 SDPEAAPARTSFSGRS---VELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSG 1170
A + + S RS +L P + R+ A + A+ P R R
Sbjct: 1974 RVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASP-RRGRPA 2032
Query: 1171 -------SARYTSTTQTPRAGSSSRARSRAPGPR 1197
S+R PR G + AR R P R
Sbjct: 2033 LPAVFLCSSRCEELRAAPRQGPAP-ARQRPPAAR 2065
Score = 50.1 bits (118), Expect = 2e-05
Identities = 164/801 (20%), Positives = 257/801 (32%), Gaps = 106/801 (13%)
Query: 374 DRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDF 433
+ P AP R+S RA RE+ + R +P+P+ PA P + + S +A +
Sbjct: 1516 EEPPAAAPTPTHRRTSAIPRA--FTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADET 1573
Query: 434 MAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDS 493
SS ++ PE P P + P G P T P P + + + ++
Sbjct: 1574 PPCYSLSSSASSLSEPE---PSEPPAVHPRGREPA--VTKDPGPGGGRDSSPSPRAAEEL 1628
Query: 494 LSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGG 553
L + + RK RA+ RP G R+ ++
Sbjct: 1629 LQRCISSALPRRRPPVSGLRRRK--------------PRATRLDERPA-EGSRERGEEAA 1673
Query: 554 VAQRMALLQEFASRPLGAAPQA----EHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTE 609
+ R + L R + + HQ + S S +
Sbjct: 1674 GSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSES--DSILSFVSGLSVGSTLQ 1731
Query: 610 DGLGRRGGEPEGSLPVRMRRRLPQLPSERAD----SPAGPESSRRSGPGPPELDSEQPSR 665
R+G + EG + R S + SPAGPE R + P + P+
Sbjct: 1732 PPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGV----PAV 1787
Query: 666 LFGQEEL---DPDSLSDASGSDGGRGPEPGVEP-----QDSRRRSPQEGPTWSRGRRSPR 717
L G+ + P + G+ G R V P + + P G SR P
Sbjct: 1788 LRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPA 1847
Query: 718 APGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQ 777
E S A L++ P ++ +QP P R V +A
Sbjct: 1848 KTSELATLSQPPRSATPPARLAKTPSSSSSQ---TSPASQPLPRKRPPVTQAAGALP--- 1901
Query: 778 LRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 837
PG SP P PA L ++ T+ P +P PL + +
Sbjct: 1902 -GPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGR---- 1956
Query: 838 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 897
TE A RL V + GS S D ++
Sbjct: 1957 -------AGTEAGPGARGGRLGLVRVASALSSGSE--------SSDRSGFRRQLTFIKE- 2000
Query: 898 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGT----------ALVSAREQSSERQHHP-LG 946
+P R + E+S + AA P G A+ + E + P G
Sbjct: 2001 -------SPGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQG 2053
Query: 947 PTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRL 1006
P + P R + G RP S R PV A + + P + A
Sbjct: 2054 PAPARQRPPAARPS--PGERPARRTTSESPSRLPVRAPAARPETVKRYASLPHISVA--- 2108
Query: 1007 GSRRKPAAPPPSPAAREEQSRSSASSQKG-PQALTRSNSLSTPRPTRASRLRRARLGDAS 1065
RR A P +PA+ + RSS + P+ + R + R+ L
Sbjct: 2109 --RRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRSTL---- 2162
Query: 1066 DTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTG--TSDPEAAPA-- 1121
A RGS P G P + + + + + +A P+ + + T +P APA
Sbjct: 2163 -PATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGG 2221
Query: 1122 RTSFSGRSVELCCASRKPTMA 1142
+ S G V+ ++ P A
Sbjct: 2222 QLSLLGSDVDGPSLAKAPISA 2242
Score = 35.8 bits (81), Expect = 0.32
Identities = 79/333 (23%), Positives = 131/333 (39%), Gaps = 60/333 (18%)
Query: 893 SLRSGKSGPSPTTPQPLRAQKEM---SPSPPAAQDPGGTALVSAREQSSERQHHPL--GP 947
+L S + P P+P R ++ PPA + A V + S QH PL G
Sbjct: 949 ALASRREDPRCGQPRPSRLDLDLPGCQAEPPAREATSADARVRTIKLSPTYQHVPLLEGA 1008
Query: 948 TDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLG 1007
+ G EP+ I G R + A LP+ + + PE
Sbjct: 1009 SRAG-AEPLAGPGISPGARKQ--------------AWLPADHLS----KVPE-------- 1041
Query: 1008 SRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDT 1067
K AA P S A++ Q ++Q+GP +L+R +SLS+ + A R + GD D+
Sbjct: 1042 ---KLAAAPLSVASKALQK---LAAQEGPLSLSRCSSLSS--LSSAGRPGPSEGGDLDDS 1093
Query: 1068 EAADGERGSLGNPEPVGRPAAE-----QAKKLSRLDI-LAMPRKRAGSFTGTSDPEAAPA 1121
++ SL E G AE +A + L + + PR+ G G D A P+
Sbjct: 1094 DS------SLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVED--ATPS 1145
Query: 1122 RTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTP 1181
+S + SR + ++ + + ++ P +P S SG+ S ++ P
Sbjct: 1146 SSSENYVQETPLVLSR---CSSVSSLGSFESPSIASSIPSEPCSGQGSGT---ISPSELP 1199
Query: 1182 RAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQ 1214
+ + SR+ P + P+ F +Q
Sbjct: 1200 DSPGQTMPPSRSKTPPLAPAPQGPPEATQFSLQ 1232
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.0 bits (149), Expect = 4e-09
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 125/876 (14%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 341
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 397
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 398 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 452
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 453 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 502
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 503 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 543
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 544 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 595
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 596 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 653
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 711
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 771
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 772 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 830
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 831 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 889
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 890 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 949
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 1047 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1088
Query: 950 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1009
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1089 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1125
Query: 1010 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1058
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1126 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETLVE 1184
Query: 1059 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1093
++S+ + + L G P PA QA K
Sbjct: 1185 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
Score = 61.2 bits (147), Expect = 7e-09
Identities = 249/1219 (20%), Positives = 413/1219 (33%), Gaps = 242/1219 (19%)
Query: 159 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 215
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 216 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 270
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 271 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 325
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 326 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 375
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 376 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 435
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 436 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 495
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 496 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 554
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 555 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 614
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 615 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 664
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 665 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 723
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 724 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 764
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 823
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 824 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 883
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 884 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 943
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 944 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1001
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1002 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1060
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1061 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSD 1115
++ D + PA + R +++ MP S G S
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
Query: 1116 PEAAPARTSFSGRSVELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS 1169
+ + + + S+K T A + +++KA+ QP S S
Sbjct: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1102
Query: 1170 --GSARYTS--TTQTPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEI 1218
G+ TS +T G++ + + P P +DD E+ D + E
Sbjct: 1103 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
Query: 1219 AEIAR----------LSQTLVKDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSN 1262
+ A+ ++TLV++ A + E DV +L S PA+S +
Sbjct: 1163 PQGAKSAHTLGPTPSRTETLVEETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKA 1221
Query: 1263 MP---STP--ASTISAREE 1276
P S+P +ST++A+++
Sbjct: 1222 TPKLDSSPSVSSTLAAKDD 1240
Score = 53.5 bits (127), Expect = 1e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 588 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 646
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 647 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 706
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 707 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 764
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 824
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 825 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 870
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 871 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 903
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 904 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 954
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 955 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 997
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 998 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1035
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1036 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1095
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1096 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1153
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1154 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1207
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 62.0 bits (149), Expect = 4e-09
Identities = 245/1198 (20%), Positives = 409/1198 (34%), Gaps = 238/1198 (19%)
Query: 159 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 215
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 216 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 270
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 271 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 325
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 326 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 375
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 376 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 435
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 436 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 495
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 496 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 554
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 555 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 614
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 615 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 664
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 665 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 723
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 724 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 764
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 823
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 824 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 883
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 884 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 943
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 944 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1001
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1002 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1060
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1061 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1120
++ D + PA + R +++ MP T+ P AP
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMP---------TAHPRIAP 1033
Query: 1121 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFS-RARSGSARYTSTTQ 1179
+ S +G S + +++ + A + G S ++ S A+ T+ +
Sbjct: 1034 -KASMAGAS----SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 1180 TPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIAR----------LSQTLV 1229
P+ +A P +DD E+ D + E + A+ ++TLV
Sbjct: 1089 KPKLPEVQQA---TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV 1145
Query: 1230 KDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSNMP---STP--ASTISAREE 1276
++ A + E DV +L S PA+S + P S+P +ST++A+++
Sbjct: 1146 EETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1202
Score = 55.8 bits (133), Expect = 3e-07
Identities = 175/928 (18%), Positives = 298/928 (32%), Gaps = 113/928 (12%)
Query: 283 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 341
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 397
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 398 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 452
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 453 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 502
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 503 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 543
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 544 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 595
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 596 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 653
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 711
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 771
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 772 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 830
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 831 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 889
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 890 STVSLRSGKSGPS-----------PTTPQPLRAQ-----KEMSPSPPAAQDPGGTALVSA 933
S +S + GP+ T+PQ Q K P P Q T +
Sbjct: 1047 SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPES 1104
Query: 934 REQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMA- 992
+ S + G + G G +SA G P + E A DV+A
Sbjct: 1105 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEE----TAAESSEDDVVAP 1160
Query: 993 -----SNHETPEATGAGRLGSRRKP-----------AAPPPSPAAREEQSRSSASSQKGP 1036
S + TP T A S+ P A P ++E A+ P
Sbjct: 1161 SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSP 1220
Query: 1037 QALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGE--RGSLGNPEPVGRPAAEQAKKL 1094
+ + + T P ++ + ++ + T A + LG P P+ + +
Sbjct: 1221 KTGGKEAASGT-TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVK 1279
Query: 1095 SRLDILAMPRKRAGSFTGTSDPEAAPAR 1122
++L RK+ T S + +R
Sbjct: 1280 VLTELLEQERKKVVDTTKESSRKGWESR 1307
Score = 53.5 bits (127), Expect = 1e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 588 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 646
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 647 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 706
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 707 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 764
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 765 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 824
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 825 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 870
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 871 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 903
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 904 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 954
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 955 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 997
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 998 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1035
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1036 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1095
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1096 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1153
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1154 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1207
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 61.6 bits (148), Expect = 5e-09
Identities = 180/758 (23%), Positives = 257/758 (33%), Gaps = 120/758 (15%)
Query: 360 PKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARP 419
P ++ G T +D D P+ + R GP R E L S SPA P P
Sbjct: 132 PDSEAYYGETDSDADGPATQEKPRRP-RRRGPTRPTPPGAPPDEVYL-SDSPAEPAPTIP 189
Query: 420 FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGP-------PT 472
SR+ SSP+ PP A L PHG GP P
Sbjct: 190 GPPSQGDSRV-----------SSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPV 238
Query: 473 PPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSR 532
P P D T +K ++ A E+ Q+ ++EA+ + +L +
Sbjct: 239 PHPVAEDLTTTYTQKAKQ------AKLQRAES-LQEKSIKEAKTKCRTIASLLTAAPNPH 291
Query: 533 ASSATF--RPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQK 590
+ + R + G A +E P + E
Sbjct: 292 SKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSD 351
Query: 591 WVSRWASLADSYSDPGLTE---DGLGRRGGEPEG---SLPVRMRRRLPQLPSERAD-SPA 643
W S + + + + +E GLG + E G L + R+R E A PA
Sbjct: 352 WDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPA 411
Query: 644 ------GPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRG---PEPGVE 694
G +S R+ PPE PS L P ++ G G P P +
Sbjct: 412 AMLNGEGLQSPPRAQSAPPEAAVLPPSPL-------PAPVASPRPFQPGGGAPTPAPSIF 464
Query: 695 PQDSRRRSP---QEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG 751
+ +R +P + PT + P AP + + + S+ P P G
Sbjct: 465 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 524
Query: 752 LGQTA----QPSPPARDG-------VYVSANGRMVIQLRPGRSPEPDGPAPAF------- 793
+ A PS P G +Y+ A R V PG +PEP P A
Sbjct: 525 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPV---TPGGAPEPPAPPSAAAMTSTAS 581
Query: 794 ------LRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT----RAARMDFHSQDTHLI 843
LR + + PA GP AP +PP + A T A R Q
Sbjct: 582 IFLSAPLRPSARPEAPAPGPGAP-EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPG 640
Query: 844 LKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS-GDSDVDTASTVSLRSGKSGP- 901
+ET+ + L+ N + GG+ P EDALS G + V RS K+ P
Sbjct: 641 KEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH 700
Query: 902 -SPTTPQPL--RAQKEMSPS--PPAAQDPGGTALVSAR-EQSSERQHHPLGPTDMGRGEP 955
+P TP P+ + M+P PP A P L+ ++ P P GRG
Sbjct: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 760
Query: 956 V---RRSAIRR-----------GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1001
+ R+S R G RPR PS LP S + N P
Sbjct: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPS---------LPPSWKYSPNIRAPPPI 811
Query: 1002 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQAL 1039
L S P A P A+ + R A+ ++G +AL
Sbjct: 812 AYNPLLSPFFPQAARTLPKAQSQGPR--ATPKQGIKAL 847
Score = 35.8 bits (81), Expect = 0.32
Identities = 35/119 (29%), Positives = 44/119 (36%), Gaps = 10/119 (8%)
Query: 346 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGG-----RSSGPQRAGSLKRE 400
K+ + S P +GPTP VP+ G RSSGP A S
Sbjct: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552
Query: 401 KTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAP 459
R +P A PA P S + A F++ LR P+ARP P P P
Sbjct: 553 PAPSRPVTPGGAPEPPAPP--SAAAMTSTASIFLSAPLR---PSARPEAPAPGPGAPEP 606
Score = 33.9 bits (76), Expect = 1.2
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 15/140 (10%)
Query: 356 PSGDPKADKRR--GPTPADRDRPSVPAPVQAGGRSSGPQRAGSLK---REKTEERLGSPS 410
PS P+A P P + P G +R G+ K R EE SP+
Sbjct: 590 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649
Query: 411 PASRT-------PARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVP---PVLPAPL 460
P + R G+ A A+ P S + +P P P P+
Sbjct: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709
Query: 461 TPHGTSPVGPPTPPPAPTDP 480
P P+ P TPPP P
Sbjct: 710 APKTPPPMTPKTPPPVAPKP 729
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 60.8 bits (146), Expect = 9e-09
Identities = 117/518 (22%), Positives = 174/518 (33%), Gaps = 100/518 (19%)
Query: 345 RKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEE 404
R+ RS+S ++SP P RR P+P R P P RS P R +R +
Sbjct: 300 RRHRSRSRSYSPRRRPSP--RRRPSPRRRTPPRRMPPPPRHRRSRSPVRR---RRRSSAS 354
Query: 405 RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK---VPPVLPAPLT 461
GS S +S + +R S ++ + R SP+A P + PP P P T
Sbjct: 355 LSGSSSSSSSSRSR---SPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT 411
Query: 462 PHGTSPV-------GPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEA 514
H +P + P T ++TK + E+ +S S A + E ++E ++
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR-KVELSESEEDKG 470
Query: 515 RKMI--DQV-----FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 567
KM D V + S + S++ R R +G V +R ++
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530
Query: 568 PLG-----------------AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTED 610
P + P + P P P ++ + S P
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR--- 587
Query: 611 GLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPP-------ELDSEQP 663
RR P P RR P P +R + P RR+ P PP +Q
Sbjct: 588 ---RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Query: 664 SRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT 723
S + S GS R PQ ++R SP P R+P+ P
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP------RAPQTSSSPP 698
Query: 724 PASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS 783
P G + PSP R VS R+
Sbjct: 699 P-------------------VRRGASSSPQRRQSPSPSTRPIRRVS------------RT 727
Query: 784 PEPD------GPAPAFLRQESFTKEPASGP-PAPGKPP 814
PEP P+P +R+ S ++ + P PA KPP
Sbjct: 728 PEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 765
Score = 55.8 bits (133), Expect = 3e-07
Identities = 134/617 (21%), Positives = 208/617 (33%), Gaps = 132/617 (21%)
Query: 362 ADKRRGPTPADRDRPSVPAPVQAGGRSSGPQ--RAGSLKREKTEERLGSPSPASRTPARP 419
+D + P P P P+P + + + R S R K+ R S SP+ P R
Sbjct: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR 301
Query: 420 FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTD 479
RSR R SP RPSP + P +P +P PPP
Sbjct: 302 -----HRSRS---------RSYSPRRRPSPRRRP-------SPRRRTPPRRMPPPPRHRR 340
Query: 480 PQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFR 539
+ R++ SLS + + + + ++ + ++ P +R S +
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-------TSSPPRKTRRLSPSAS 393
Query: 540 PVIRGDRDE-----------SDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGG 588
P R R S + R + S + +H+G SP
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
Query: 589 QKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESS 648
R L++S D +GG+ + V+ RR+ + ++++ S +G SS
Sbjct: 454 AP-KPRKVELSESEED----------KGGKMAAADSVQQRRQYRR-QNQQSSSDSGSSSS 501
Query: 649 RRSGPGPPELDSEQPSRLF---GQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQE 705
+ E+P R G+ S S R + P+ RRRSP
Sbjct: 502 S---------EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552
Query: 706 GPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDG 765
PT R RRSP +P P R P P + PSPP R
Sbjct: 553 PPT--RRRRSP-SPAPPPRR-------------RRTPTPPP-------RRRTPSPPPR-- 587
Query: 766 VYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEP----ASGPP------APGKPP- 814
RSP P +P R+ S + P AS PP +P PP
Sbjct: 588 ---------------RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 815 -HISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTP 873
+S P + ++ R H K + + + EAR S +P
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKH--RKGSSPSRSTREAR----SPQPNKRHSPSP 686
Query: 874 RPPEDALSGDSDVDTASTVSLRSGKSGPSPT---------TPQPLRAQKEMSPSPPAAQD 924
RP S S + PSP+ TP+P + +K SPSP + +
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 925 PGGTALVSAREQSSERQ 941
+ VS + + ++
Sbjct: 747 VSSSRSVSGSPEPAAKK 763
Score = 55.1 bits (131), Expect = 5e-07
Identities = 133/618 (21%), Positives = 206/618 (33%), Gaps = 112/618 (18%)
Query: 30 RVQHRVPEEALKHEKYTSQL-QVSVKGLAPKRSEA--------LPEHTPYCEASNPRPEK 80
R + R P A + ++ T +L + SVK P EA +P+ P E P PEK
Sbjct: 204 RTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEK 263
Query: 81 GDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDGELHGFRA 140
++ E +T + S R P RP+ + + R
Sbjct: 264 NSKK---EKEKEKTRPRSRSR-------SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR 313
Query: 141 PAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFT 200
P RR PS P + TP PP P H +A + S +S +
Sbjct: 314 RPSP-----RRRPS----PRRRTPPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 201 IEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVG 260
P K + T R+ R A+P + A P H
Sbjct: 364 SSRSRSPPKKPPKR---TSSPPRKTRRLSPSASPPRRRHRPSPPAT----PPPKTRHSPT 416
Query: 261 PGDDRHSTKSDLPVHTRTLKGH--KHEDGTQSDSEDPLAKAASAAGVPLE-------ASG 311
P + KS + V G KH+ + +S P K E A+
Sbjct: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476
Query: 312 EQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTP------------RKKRSQSFTHSPSG- 358
+ V+ +RQ +R Q+ + + +++ P R++ S S + SPS
Sbjct: 477 DSVQQRRQYRRQNQQ--SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 359 ------DPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPA 412
P+ +RR P+P R P+P + P+R R +P P
Sbjct: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSP------APPPRR----------RRTPTPPPR 578
Query: 413 SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPP- 471
RTP+ P RRS + + R SP+ P K P P SP PP
Sbjct: 579 RRTPSPP---PRRRSPSPRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRASPSPPPK 632
Query: 472 -----TPPPAPTDPQLTKAR------KQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQ 520
+PPP +TK R K + S S + + R Q
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 521 VF--------GVLESPELSRASSATFRPVIRGDR----DESDDGGVAQRMALLQEFASRP 568
G SP+ ++ S + RP+ R R + ++ + +SR
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS 752
Query: 569 LGAAPQAEHQGLPVPGSP 586
+ +P+ + P P SP
Sbjct: 753 VSGSPEPAAKKPPAPPSP 770
Score = 49.3 bits (116), Expect = 3e-05
Identities = 80/308 (25%), Positives = 107/308 (34%), Gaps = 33/308 (10%)
Query: 934 REQS-SERQHHPLGPTDMGRGEPVRRSAIRRG-----HRPRGSLDWPSEERGPVLAHLPS 987
RE+S S R+ P+ R PVRR R HR + P+ E+ LP
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE 225
Query: 988 SDVMASNHETPEATGAGRLGSRRKPAA-PPPSPAAREEQSRSSASSQKGPQALTRSNSLS 1046
V EAT + KP P P + E+ S+ +K + +RS S S
Sbjct: 226 PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK-TRPRSRSRSKS 284
Query: 1047 -------TPRPTRASRLRRARLGDASD-TEAADGERGSLGNPEPVGRPAAEQAKKLSRLD 1098
+P TR R R+R S + R S P R + SR
Sbjct: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
Query: 1099 ILAMPRKRAGSFTGTSD----------PEAAPARTSFSGRSVELCCASRKPTMAEARAVS 1148
+ R+ + S +G+S P+ P RTS R S P R
Sbjct: 345 V-RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP 403
Query: 1149 RKAANTATTTGPR-QPFSRAR----SGSARYTSTTQTPRAGSSSR-ARSRAPGPRDTDDD 1202
T P Q +R R S S TS T G+ R + S AP PR +
Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463
Query: 1203 EEEPDPYG 1210
E E D G
Sbjct: 464 ESEEDKGG 471
Score = 49.3 bits (116), Expect = 3e-05
Identities = 90/423 (21%), Positives = 142/423 (33%), Gaps = 60/423 (14%)
Query: 888 TASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGG--TALVSAREQSSERQHHPL 945
T+ V+ G +P P + E+S S +D GG A S +++ R+ +
Sbjct: 435 TSGKVTKHKGTEKRESPSPAPKPRKVELSESE---EDKGGKMAAADSVQQRRQYRRQNQQ 491
Query: 946 GPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGR 1005
+D G +R H G E G H PS S + + T
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNG-------EVGRRRRHSPSRSASPSPRKRQKETSPR- 543
Query: 1006 LGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS 1065
G RR+ +PPP+ R ++ P R + S P R+ RR
Sbjct: 544 -GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR------- 595
Query: 1066 DTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSF 1125
+ +R +P P R A+ R P++R S P +
Sbjct: 596 --YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH----SPPPKQRSSPVT 649
Query: 1126 SGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTP--RA 1183
RS L RK + ++ A + P + S + A TS++ P R
Sbjct: 650 KRRSPSLSSKHRKGSSPS------RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703
Query: 1184 GSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQ--TLVKDVAILAQEIHD 1241
SSS R ++P P T I ++R + + K + Q +
Sbjct: 704 ASSSPQRRQSPSP-----------------STRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 1242 VAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVP-PGSLNSRD 1300
V+ GS EPA + P P S + ++ P + K P P R+
Sbjct: 747 VSSSRSVSGSPEPA-----AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 1301 FDQ 1303
DQ
Sbjct: 802 SDQ 804
Score = 46.2 bits (108), Expect = 2e-04
Identities = 142/629 (22%), Positives = 206/629 (32%), Gaps = 75/629 (11%)
Query: 526 ESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGS 585
++PEL S P ++ SD V + + + P + + + + P S
Sbjct: 219 KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRS 278
Query: 586 PGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGP 645
K SR S + S++ P RR S R R + PS R +P
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPR-------RRHRSRSRSYSPRRRPSPRRRPSPRRRTPP-- 329
Query: 646 ESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP------EPGVEPQDSR 699
RR P P S P R + S +S S R P P+ +R
Sbjct: 330 ---RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
Query: 700 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG-------DGEGL 752
R SP P R R SP A P Q+ SR + +PG +G
Sbjct: 387 RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV-SPGRTSGKVTKHKGT 445
Query: 753 GQTAQPSP-PARDGVYVSANGRMVIQLRPGRSPEPDG-PAPAFLRQESFTKEPASGPPAP 810
+ PSP P V +S + + + G+ D R+++ SG +
Sbjct: 446 EKRESPSPAPKPRKVELSESE----EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS 501
Query: 811 GKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGG 870
+ + R S ++ ET+ R S
Sbjct: 502 SEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP 561
Query: 871 STPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPP-----AAQDP 925
S P PP + T S + PSP P Q+ SPSPP A+ P
Sbjct: 562 S-PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPPP 619
Query: 926 GGTALVSAREQSSERQHHPLGPTDMGRGEPV--RRSAIRRGHRPRGSLDWPSEERGPVLA 983
S R H P R PV RRS +GS S R A
Sbjct: 620 PPKRRASPSPPPKRRVSH--SPPPKQRSSPVTKRRSPSLSSKHRKGS----SPSRSTREA 673
Query: 984 HLPSSDVMASNHETPEATGAGRLGSRRKPAAPPP--SPAAREEQSRSSASSQKGP-QALT 1040
P + S P A + ++PPP A+ Q R S S P + ++
Sbjct: 674 RSPQPNKRHSPSPRPRAP--------QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725
Query: 1041 RSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGR-----PAAEQAKKLS 1095
R TP P ++++A R G+PEP + P+ Q++ S
Sbjct: 726 R-----TPEP---KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Query: 1096 RLDILAMPRKRAGSFTGTSDPEAAPARTS 1124
A+P K+A S T P +P R S
Sbjct: 778 TNWSPAVPVKKAKSPT----PSPSPPRNS 802
Score = 43.1 bits (100), Expect = 0.002
Identities = 93/465 (20%), Positives = 158/465 (33%), Gaps = 56/465 (12%)
Query: 59 KRSEALPEHTPY-CEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQ 117
KR P P E S +KG + ++ R Q D GS+
Sbjct: 447 KRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED-- 504
Query: 118 GEPYPERPKGPVQQDGELHGFRAPAEPQGCS---------------FRREPSYFEIPTKE 162
ERPK ++GE+ R + + S RR PS +
Sbjct: 505 -----ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR 559
Query: 163 TPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHAS------FTIEFDDCSPGKMKIKDH 216
+P P+ PP PT P +S + + P K +
Sbjct: 560 SPSPAPPPR--RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617
Query: 217 ITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLL--HRVGPGDDRHSTKSDLPV 274
R P + + + + + PSL HR G R + ++ P
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
Query: 275 HTRTLKGHKHEDGTQ-SDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQA 333
+ Q S S P+ + AS++ ++ R R++ R P+ + A
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Query: 334 FVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQR 393
+P+ R S + S SG P+ PA + P+ P+PVQ+ S+
Sbjct: 738 -------SPSPQSVRRVSSSRSVSGSPE--------PAAKKPPAPPSPVQSQSPSTNWSP 782
Query: 394 AGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK-V 452
A +K+ K+ +PSP+ + G G++ + +D + ++ + EK V
Sbjct: 783 AVPVKKAKSP----TPSPSPPRNSDQEGG-GKKKKKKKDKKHKKDKKHKKHKKHKKEKAV 837
Query: 453 PPVLPAPLTPHGTSPVGPPTPPPAP-TDPQLTKARKQEEDDSLSD 496
A +TP + P P+ K + E +D+L D
Sbjct: 838 AAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDD 882
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 58.5 bits (140), Expect = 5e-08
Identities = 134/538 (24%), Positives = 180/538 (33%), Gaps = 70/538 (13%)
Query: 578 QGLP-VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEP--EGSLPVRMRRRLP-- 632
+G P +PGSPG S DPG+ G G P +GS R P
Sbjct: 1027 RGAPGIPGSPG-------------SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073
Query: 633 QLPSERADSPAGPESSRRSGPGPPELDSE-QPSRLFGQEELDPDSLSDASGSDGGRGPEP 691
Q P+ R +P P R PG P L S P + L D +D G P
Sbjct: 1074 QGPAGRDGAPGNP--GERGPPGKPGLSSLLSPGDI---NLLAKDVCNDCPPGPPGLPGLP 1128
Query: 692 GVEPQDSRRRSP-QEGPTWSRGRRSPRAPGEPTPASFF-----IGDQNGDAVLSRK-PLA 744
G + P +EG +G P PG P P G++ D + +K
Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGP--PGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 1186
Query: 745 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGPA--PAFLRQESFT 800
PG +G P PP DG+ A G IQ PG+ P P GP+ P +E
Sbjct: 1187 HPGVPGFMGPPGNPGPPGADGI-AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG-- 1243
Query: 801 KEPASGPPAPGKPPHISSHPLLQDLAATRA-ARMDFHSQDTHLILKETETALAALEAR-- 857
KE G P P P + P L R H+ D+ E+ L +
Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303
Query: 858 LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSP 917
L D G P+ P + + G+ GPS T Q + SP
Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS-------PGEPGPSGTPGQKGSKGENGSP 1356
Query: 918 SPPAAQDPGGTALVSAREQSSERQHHPLGPTDMG----RGEPVRRSAIRRGHRPRGSLDW 973
P P G + ++ P P + G RG+P I+ P G
Sbjct: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP----GIKGDKGPPGGKGQ 1412
Query: 974 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP---PPSPAAREEQSRSSA 1030
P + P H + +M E G G +P P SP+ E R
Sbjct: 1413 PGDPGIP--GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM--ETLRRLI 1468
Query: 1031 SSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS--DTEAADGERGSLGNPEPVGRP 1086
+ G Q TR L P + + R G + G G +G P GRP
Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP---GRP 1523
Score = 45.4 bits (106), Expect = 4e-04
Identities = 97/367 (26%), Positives = 123/367 (33%), Gaps = 67/367 (18%)
Query: 462 PHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQV 521
P G V T PP P PQ E+ L TI E E V
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLK-----TINCSCPAGEKGEMG-----V 488
Query: 522 FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP 581
G + P A G + E D G+ P G + E L
Sbjct: 489 AGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG------------PFGQGEKGEKGSLG 536
Query: 582 VPGSPG--GQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRR-RLPQLPSER 638
+PG PG G K + +PGL + +G RG + LP R P L ER
Sbjct: 537 LPGPPGRDGSKGM---RGEPGELGEPGLPGE-VGMRGPQGPPGLPGPPGRVGAPGLQGER 592
Query: 639 ADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP--EPGVEPQ 696
+ E R G P +P Q P ++ G G GP PGV
Sbjct: 593 GEKGTRGEKGERGLDGFP----GKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
Query: 697 DSRRRSPQEGPTWSRGRRSPR----APGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGL 752
+ QEG +G PR APG P A IG + D P +GL
Sbjct: 649 VVQ----QEGLKGEQGAPGPRGHQGAPG-PPGARGPIGPEGRD---------GPPGLQGL 694
Query: 753 -GQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGP--APAFLRQESFTKEPASGP 807
G+ PP G+ + +Q PG P P GP +P + F +P GP
Sbjct: 695 RGKKGDMGPPGIPGL-------LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKP--GP 745
Query: 808 PAPGKPP 814
P P PP
Sbjct: 746 PGPTGPP 752
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 58.5 bits (140), Expect = 5e-08
Identities = 113/450 (25%), Positives = 165/450 (36%), Gaps = 67/450 (14%)
Query: 619 PEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLS 678
P LP + P P A +PA +R + P P L ++P+ P +
Sbjct: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT--SVIFRPLAPK 269
Query: 679 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVL 738
A+ S GG P P P + P P+++ G S AP +P++ ++ V
Sbjct: 270 RANDSLGGLSPAP---PPFLSSQGPTPLPSFTSGVPS-HAPVSGSPST----PRSSGPVT 321
Query: 739 SRKPLAAPGDGEGL---GQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLR 795
+ L P + G P+PP+ + +A+ + LRP PE
Sbjct: 322 ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE---------- 371
Query: 796 QESFTKEPASGPPAPGKPPHISSHPLLQDLAAT----RAARMDFHSQDTHLILKETETAL 851
PA GP AP +PP + A T A R Q +ET+ +
Sbjct: 372 ------APAPGPGAP-EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSP 424
Query: 852 AALEARLLSNSVDAECEGGSTPRPPEDALS-GDSDVDTASTVSLRSGKSGP--SPTTPQP 908
L+ N + GG+ P EDALS G + V RS K+ P +P TP P
Sbjct: 425 NPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPP 484
Query: 909 L--RAQKEMSPS--PPAAQDPGGTALVSAR-EQSSERQHHPLGPTDMGRGEPV---RRSA 960
+ + M+P PP A P L+ ++ P P GRG + R+S
Sbjct: 485 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
Query: 961 IRR-----------GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1009
R G RPR PS LP S + N P L S
Sbjct: 545 ADRYVVEGTPGPGLGPRPRSPSPTPS---------LPPSWKYSPNIRAPPPIAYNPLLSP 595
Query: 1010 RKPAAPPPSPAAREEQSRSSASSQKGPQAL 1039
P A P A+ + R A+ ++G +AL
Sbjct: 596 FFPQAARTLPKAQSQGPR--ATPKQGIKAL 623
Score = 35.8 bits (81), Expect = 0.32
Identities = 35/119 (29%), Positives = 44/119 (36%), Gaps = 10/119 (8%)
Query: 346 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGG-----RSSGPQRAGSLKRE 400
K+ + S P +GPTP VP+ G RSSGP A S
Sbjct: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
Query: 401 KTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAP 459
R +P A PA P S + A F++ LR P+ARP P P P
Sbjct: 329 PAPSRPVTPGGAPEPPAPP--SAAAMTSTASIFLSAPLR---PSARPEAPAPGPGAPEP 382
Score = 33.9 bits (76), Expect = 1.2
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 15/140 (10%)
Query: 356 PSGDPKADKRR--GPTPADRDRPSVPAPVQAGGRSSGPQRAGSLK---REKTEERLGSPS 410
PS P+A P P + P G +R G+ K R EE SP+
Sbjct: 366 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 425
Query: 411 PASRT-------PARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVP---PVLPAPL 460
P + R G+ A A+ P S + +P P P P+
Sbjct: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
Query: 461 TPHGTSPVGPPTPPPAPTDP 480
P P+ P TPPP P
Sbjct: 486 APKTPPPMTPKTPPPVAPKP 505
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 57.0 bits (136), Expect = 1e-07
Identities = 189/810 (23%), Positives = 268/810 (33%), Gaps = 207/810 (25%)
Query: 440 ESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPP-APTDPQLTK-------------- 484
+ PA P+P P+P +P +SP PP PPP AP P +
Sbjct: 181 DGGPAPPPAPSSASSS-PSP-SPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAY 238
Query: 485 ----ARKQEED-------DSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRA 533
A +Q+ D + S AGT + E E ++ E EE + ++ E LS++
Sbjct: 239 SPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEE-----EEEGLSQS 293
Query: 534 SSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVS 593
S R G+ +L Q+F Q P PG+P
Sbjct: 294 IS----------RISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTP------- 336
Query: 594 RWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP 653
DS DG RR G+ R + A A P P
Sbjct: 337 ---PQVDS-----TRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPP------P 382
Query: 654 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGR 713
P DSE Q E +P L+ + GGR P + P P
Sbjct: 383 LLPPGDSEIEEGEIVQPEEEP-RLALSLFRPGGRAARPTPAASATPTAQPLPQPP----- 436
Query: 714 RSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG-----LGQTAQPSPPARDGVY- 767
+PRAP GD LS L A DGEG LG+ A P+PPA D +
Sbjct: 437 -APRAP-------------EGDDFLS---LHAESDGEGALQVDLGEPA-PAPPAADSRWG 478
Query: 768 -VSANGRMVIQLRP---GRSPEP-DGPAPAFL-------------RQESFTKEPAS---- 805
+ +++ Q R RSP P PAPA ++ KE AS
Sbjct: 479 GLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSG 538
Query: 806 ---GPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 862
PPAP P H +R + H+ + A +R S S
Sbjct: 539 TQPAPPAPASPWDSKKH-------RSRDRKPGSHASSS-----------ARRRSRSRSRS 580
Query: 863 VDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAA 922
ST R R G S S + + R ++ SP PPA
Sbjct: 581 RSTRRRSRSTDR--------------------RRGGSRRSRSREKRRRRRRSASP-PPA- 618
Query: 923 QDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVL 982
++ SS R+ H D G + ++ + RG + G E+ P
Sbjct: 619 ---------TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGD----GSEKAPAP 665
Query: 983 AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQ----------SRSSASS 1032
A PS +T G SRR+ A PP + R S
Sbjct: 666 APPPSG-----------STSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD 714
Query: 1033 QKGP----------QALTRSNSLS-TPRPTRASRLRRARLGDASDTEAADGERGSLGNPE 1081
+GP + L S LS R ++S+ R R G AS + ++ E+GS
Sbjct: 715 PRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAAS-SSSSSREKGSRRKAL 773
Query: 1082 PVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM 1141
G ++ + R R S + P P + S C+SRK +
Sbjct: 774 DGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKL 833
Query: 1142 AEARAVSRKAANTATTTGPRQPFSRARSGS 1171
AV + ++TT P + + A GS
Sbjct: 834 QSKVAVLIREGVSSTT--PAKDAASAGLGS 861
Score = 52.8 bits (125), Expect = 2e-06
Identities = 135/593 (22%), Positives = 198/593 (33%), Gaps = 130/593 (21%)
Query: 632 PQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEEL-DPDSLSDASGSDGGRGPE 690
P PS + SP+ SS P PP P+ + ++ DP +D + S P
Sbjct: 187 PPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYS-----PP 241
Query: 691 PGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGE 750
P E + P+ S G SP E ++ D + E
Sbjct: 242 PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEE---EEEEEDEE----------EEE 288
Query: 751 GLGQTAQPSPPARDGVYVSANGRMVIQLRPG-RSPEPDGPAPAFLRQESFTKEPASGPPA 809
GL Q+ G+Y + + Q PG SP PD +P PA
Sbjct: 289 GLSQSISRISETLAGIY---DDNSLSQDFPGDESPRPDA-------------QPTQPTPA 332
Query: 810 PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEG 869
PG PP + S TRA + + + TE A A E ++ SV+ G
Sbjct: 333 PGTPPQVDS---------TRADG----AMRRRVFVVGTE-AEACREGKV---SVEVVTAG 375
Query: 870 GSTPRPPEDALSGDSDVDTASTVS-----------LRSGKSGPSPTTPQPLRAQKEMSPS 918
G+ PP GDS+++ V R G PT + P
Sbjct: 376 GAA-LPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQ 434
Query: 919 PPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEER 978
PPA + P G +S +S + D+G P +A R G LD +
Sbjct: 435 PPAPRAPEGDDFLSLHAESDGEGALQV---DLGEPAPAPPAADSRW----GGLDLRRK-- 485
Query: 979 GPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQA 1038
++ E R R AP P+PAA GP
Sbjct: 486 -----------ILTQRRE--------RYRQRSPSPAPAPAPAA-----------AAGP-- 513
Query: 1039 LTRSNSLSTPRPTR-ASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRL 1097
PTR SR R R G+A EAA G+ P P + +KK
Sbjct: 514 -----------PTRKKSRRERKRSGEAK--EAASSSSGT--QPAPPAPASPWDSKKHRSR 558
Query: 1098 DILAMPRKRAGSFTGTSDPEAAPART-SFSGRSVELCCASRKPTMAEARAVSRKAANTAT 1156
D ++ GS +S + +R+ S S R R+ +R+ ++ +
Sbjct: 559 D------RKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRS 612
Query: 1157 TTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPG-PRDTDDDEEEPDP 1208
+ P S + S R+ + + RSR+ G R D E+ P P
Sbjct: 613 ASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAP 665
Score = 32.7 bits (73), Expect = 2.7
Identities = 67/318 (21%), Positives = 102/318 (32%), Gaps = 62/318 (19%)
Query: 159 PTKETPQPSQPPEVPAH-----------------------EMPTKDAEAGGGGAAPVVQS 195
PT+ TP P PP+V + ++ + AGG P +
Sbjct: 326 PTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLP 385
Query: 196 HASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQ----- 250
IE G++ + + +L RP G+ A P SA T A L Q
Sbjct: 386 PGDSEIE-----EGEIVQPEEEPRLALSLFRPGGRAARPTPAASA-TPTAQPLPQPPAPR 439
Query: 251 ----NDPSLLHRVGPGDDR---------------HSTKSDLPVHTRTLKGHKHEDGTQSD 291
+D LH G+ S L + + L + +S
Sbjct: 440 APEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSP 499
Query: 292 SEDPLAKAASAAGVPLEASGEQVRLQR-QIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQ 350
S P A+AAG P + R + + K Q A D+ K+ +
Sbjct: 500 SPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDS---KKHR 556
Query: 351 SFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPS 410
S P + RR R R + R G +R+ S ++ + R SP
Sbjct: 557 SRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPP 616
Query: 411 PASRTPARPFGSVGRRSR 428
PA+ + S RR R
Sbjct: 617 PATSS-----SSSSRRER 629
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 57.0 bits (136), Expect = 1e-07
Identities = 149/715 (20%), Positives = 232/715 (32%), Gaps = 126/715 (17%)
Query: 571 AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGE---PEGSLPVRM 627
++P+ + G+ + GG +S+ A+ G G R G+ P G+ P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAA--------GSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 628 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFG------QEELDPDSLSDAS 681
+ P R+ + PE S S P PP + + G Q D
Sbjct: 363 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 682 GSDGGRGPEPGVEPQDSR-RRSP-QEGPTWSRGRRSPRAP----------------GEPT 723
P Q S SP GPT R + SP P +P
Sbjct: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ 482
Query: 724 PASFFIGDQNGDAVLSRKPLA----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 779
+S + G G R P+ PG G+ Q PP VS + Q
Sbjct: 483 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
Query: 780 PGRSPEPDGPAP-----------AFLRQESFTKE---PASGPP-APGKPPHISSHPLLQD 824
+ P+P P + Q+ ++E S PP APGKP H
Sbjct: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH--------- 593
Query: 825 LAATRAARMDFHSQDTHLILKETETALAALEARL----------LSNSVDAECEGGSTPR 874
+D +LI +E ++L L + LS++V A GST
Sbjct: 594 -------------EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSA---SGSTSS 637
Query: 875 PPEDALSGDSDVDTASTVSLRSGKSGPSPT-TPQPLRAQKEMSPSPPAAQDPGGTALVSA 933
+ + S ++ L S GPSP+ P+ + + S A PG
Sbjct: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
Query: 934 REQSSERQHHP-LGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDV 990
SE HP L + M P R + R + ++ GP ++ PS +
Sbjct: 698 PGSQSESSSHPALSQSPM----PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 991 MASNHETPEATGAGRLGSRRKPAAP------PPSPAAREEQSRSSASSQKGPQALTRSNS 1044
A ++ +G G + P PP+ + S S G A + +
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 1045 LSTPRPTRASRLRR------------ARLGDASDTEAADGERG--SLGNPEPVGRPAAEQ 1090
+P A L R + + + ++G +G P P A++
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQE 873
Query: 1091 AKKLSRLDILAMPRKRAGSFTG--------TSDPEAAPARTSFSGRSVELCCASRKPTMA 1142
A + R GSF G +S P + P S S + + S P M
Sbjct: 874 AAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMV 933
Query: 1143 EARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGS-SSRARSRAPGP 1196
+ A S A+ + + P G T ++ S SS+ S+ P P
Sbjct: 934 NSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP 988
Score = 33.5 bits (75), Expect = 1.6
Identities = 55/258 (21%), Positives = 94/258 (36%), Gaps = 44/258 (17%)
Query: 621 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPP-------ELDSEQPSRLFGQEELD 673
G+ +M + PQ R + +G S+ SGPGP ++ + PS+ G L
Sbjct: 767 GTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLG 826
Query: 674 ------------PDSLSDASGSDGGRGPE--PGV-EPQDSRRRSPQEGPTWSRGRRSPRA 718
P ++S + S G + PG+ P + R QE + A
Sbjct: 827 RMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA---AAAVMQAAA 883
Query: 719 PGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMV--- 775
+ F G + S P + P + Q P + V+++ V
Sbjct: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLA 943
Query: 776 IQLRPGRSPEP-----DG-----PAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDL 825
+ PG S P DG P P ++S++ + S PP PG + P+ +
Sbjct: 944 DMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPG------NLPVPSPM 997
Query: 826 AATRAARMDFHSQDTHLI 843
+ + A+ FH ++ I
Sbjct: 998 SPSSASISSFHGDESDSI 1015
Score = 33.5 bits (75), Expect = 1.6
Identities = 48/212 (22%), Positives = 79/212 (37%), Gaps = 15/212 (7%)
Query: 616 GGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP----PELDSEQPSRLFGQEE 671
G P G +P + P + + +P+ P S++ GPG P ++ + +
Sbjct: 821 GAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQ 880
Query: 672 LDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEP-----TPAS 726
+S GS G + G+ S P + ++P P + AS
Sbjct: 881 AAANSAQSRQGSFPGMN-QSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939
Query: 727 FFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEP 786
+ D S+ PL DG+ G T QP ++D S+ G + PG P P
Sbjct: 940 VGLADMMSPGE-SKLPLPLKADGKEEG-TPQPESKSKDSY--SSQG-ISQPPTPGNLPVP 994
Query: 787 DGPAPAFLRQESFTKEPASGPPAPGKPPHISS 818
+P+ SF + + +PG P SS
Sbjct: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 56.6 bits (135), Expect = 2e-07
Identities = 186/779 (23%), Positives = 255/779 (32%), Gaps = 133/779 (17%)
Query: 470 PPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPE 529
PP P P P D Q K + D LSD E +A T E ++ L P
Sbjct: 634 PPPPEPTPADCQSPKMTTFQ-DSELSD------ELQAAMTGPAEVGPTTEKPSSHL--PP 684
Query: 530 LSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR--PLGAAPQAEHQGL-----PV 582
RA++ R +S GG A+ M+ QE P ++P + Q P
Sbjct: 685 TPRATT----------RQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPA 734
Query: 583 PGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSP 642
PG+P + + PG + R P +P + R+ LP P +P
Sbjct: 735 PGTPPRE-------------ARPGRHGHSIKRASVPP---VPGKPRQVLP--PGTSHFTP 776
Query: 643 AGPESSRRSGPGPPEL--DSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR 700
P++ ++ PG P+ P+ + + P L R P PQ
Sbjct: 777 --PQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTE-----RPMSPRSLPQSPTH 829
Query: 701 RS-PQEGPTWSRGRRSPRAPGE-----PTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQ 754
R P G P APG PT DA R A
Sbjct: 830 RGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNR---Y 886
Query: 755 TAQPSPPARDGVYV--SANGRMVIQLRPGRSPEPDGPAPA---FLRQESFTKEPAS-GPP 808
A S P RD + V +A +Q R GRS PA A R +SF P GPP
Sbjct: 887 AASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPP 946
Query: 809 APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARL-----LSNSV 863
P PP SS L A D + E E L + A+ L+ SV
Sbjct: 947 PP--PPKRSSSALASANLA-----------DEPVPDAEPEDGLLGVRAQCRRASDLAGSV 993
Query: 864 DAECEGGSTPRPPEDALSGDSDVDTASTVSLR--SGKSGPSPTTPQPLRAQKEM-SPSPP 920
D G A+ S + + R G P P +P+P R + S
Sbjct: 994 DTGSAGSVKSIA---AMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHK 1050
Query: 921 AAQDPGGTALVSAREQSSERQHHPLGPTDMGRGE-----PVRRSAIRRGHRPRGSLDWPS 975
A PGG +V+ R S L G GE P R RPRG +
Sbjct: 1051 EAIGPGGE-VVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGR-QRPRGPSKGEA 1108
Query: 976 EERGPVLAHLPSSDVMA------SNHE-------TPEATGAGRLGSRRKPAAPPPSPAAR 1022
GP LA + +S + N + T T R ++ + A P P P
Sbjct: 1109 GVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLS 1168
Query: 1023 EEQS------RSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGS 1076
+ R AS Q GP L + P PT + L +GE
Sbjct: 1169 VYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHL--------PPLPPPEGEARK 1220
Query: 1077 LGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCAS 1136
P +P Q + +L P + G PE A + S +
Sbjct: 1221 PAKPPVSPKPVLTQP--VPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPK----- 1273
Query: 1137 RKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPG 1195
P + V A + + GP S AR A TP + +S A+ +PG
Sbjct: 1274 PPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPG 1332
Score = 56.6 bits (135), Expect = 2e-07
Identities = 103/417 (24%), Positives = 143/417 (34%), Gaps = 82/417 (19%)
Query: 120 PYPERPKGPVQQD-GELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAH--- 175
P P VQ+ G H RAPA + R S+ P K+ P P P +
Sbjct: 901 PAAAGPYATVQRRVGRSHSVRAPAGADK-NVNRSQSFAVRPRKKGPPPPPPKRSSSALAS 959
Query: 176 ----EMPTKDAEAGGG--GAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSL------R 223
+ P DAE G G + + D S G +K + + S
Sbjct: 960 ANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRA 1019
Query: 224 QRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHR--VGPGDDRHSTKSDLPVHTRTL-- 279
RRPP TP +VA L S+ H+ +GPG + + + L L
Sbjct: 1020 ARRPPEGHPTPRPASPEPGRVATVLA----SVKHKEAIGPGGEVVNRRRTLSGPVTGLLA 1075
Query: 280 -----------KGHKHEDGT-QSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQEL 327
G EDGT + P A G PL L+R+I+
Sbjct: 1076 TARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAK---- 1131
Query: 328 LHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRR-GPTPADRDRPSVPAPVQAGG 386
NQQ V E K+R PKA +R GP P P P+
Sbjct: 1132 -QNQQENVKFILTESDTVKRR-----------PKAKEREAGPEP--------PPPLSVYH 1171
Query: 387 RSSGPQRAGSLKREKTEERLGSPSPASRTPAR----------PFGSVGRRSR---LAQDF 433
+G R + L P P + P P G + ++ +
Sbjct: 1172 NGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPV 1231
Query: 434 MAQCLRESSPAARPSPEKVPPVLPAPLTP-----HGTSPVGPPTPPPAPTDPQLTKA 485
+ Q + + + P+ +KVP LP P +P HGT P P PPP PT P+ KA
Sbjct: 1232 LTQPVPKLQGSPTPTSKKVP--LPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA 1286
Score = 46.2 bits (108), Expect = 2e-04
Identities = 185/853 (21%), Positives = 261/853 (30%), Gaps = 194/853 (22%)
Query: 159 PTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHIT 218
PT E P PP A T ++ GG A + S D PG
Sbjct: 673 PTTEKPSSHLPPTPRA----TTRQDSSLGGRARHMSSSQEL---LGDGPPGPSSPMSRSQ 725
Query: 219 KFSLRQRRPPG---KEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVH 275
++ L + PG +EA PG + + + V P +V P H T P
Sbjct: 726 EYLLDEGPAPGTPPREARPGRHGHSIKRAS---VPPVPGKPRQVLPPGTSHFTPPQTPTK 782
Query: 276 TRTLKGHKHEDGTQSDSEDPLAKAASAAGVP----LEASGEQVRLQRQIKRDPQELLHNQ 331
TR G+ P A + A V L E+ R + PQ H
Sbjct: 783 TRP--------GSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSL---PQSPTHRG 831
Query: 332 QAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGP 391
A+V+ P+ + +P P P P++ P +A P
Sbjct: 832 FAYVL-------PQPVEGEVGPAAPGP--------APPPVPTAVPTLCLPPEADAEPGRP 876
Query: 392 Q-RAGSLKR----EKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQC------LRE 440
+ RA SL R + ER PA+ A P+ +V RR + A R
Sbjct: 877 KKRAHSLNRYAASDSEPERDELLVPAA---AGPYATVQRRVGRSHSVRAPAGADKNVNRS 933
Query: 441 SSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTY 500
S A RP + GPP PPP + L A +E ++
Sbjct: 934 QSFAVRPRKK------------------GPPPPPPKRSSSALASANLADEPVPDAEPEDG 975
Query: 501 TIETEAQDTEVEEARKMID--------QVFGVLESPELSRASSATFRPVIRGDRDES--- 549
+ AQ + +D + +LE + A RP
Sbjct: 976 LLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASP 1035
Query: 550 DDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPG-LT 608
+ G VA +A ++ +G + ++ + G G +R +DPG
Sbjct: 1036 EPGRVATVLASVKH--KEAIGPGGEVVNRRRTLSGPVTGLLATARRGP--GESADPGPFV 1091
Query: 609 EDGLGR---RG---------GEP----EGSLPVRMRRRLPQLPSERAD-----------S 641
EDG GR RG G P E S ++ R R Q E
Sbjct: 1092 EDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRR 1151
Query: 642 PAGPESSRRSGPGPPE-----------LDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE 690
P E R +GP PP + S G EL P A
Sbjct: 1152 PKAKE--REAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPP-PPAEPPPTDLAHL 1208
Query: 691 PGVEPQDSRRRSPQEGPTWSRG---RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 747
P + P + R P + P + + P+ G PTP S + PL PG
Sbjct: 1209 PPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTS------------KKVPLPGPG 1256
Query: 748 DGE-----GLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKE 802
E G P PP ++ G GP+PA
Sbjct: 1257 SPEVKRAHGTPPPVSPKPPP------PPTAPKPVKAVAGLPSGSAGPSPA--------PS 1302
Query: 803 PASGPPA-----PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEAR 857
PA PPA PG PP + + P A H+ K A AA A
Sbjct: 1303 PARQPPAALAKPPGTPPSLGASPAKPPSPGAPAL---------HVPAKPPRAAAAAAAA- 1352
Query: 858 LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSP 917
+ P PPE A GDS S + + + +R + P
Sbjct: 1353 -----------AAAPPAPPEGASPGDSARQKLEETS--ACLAAALQAVEEKIRQEDAQGP 1399
Query: 918 SPPAAQDPGGTAL 930
AA+ G+ L
Sbjct: 1400 RDSAAEKSTGSIL 1412
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 56.6 bits (135), Expect = 2e-07
Identities = 172/761 (22%), Positives = 252/761 (33%), Gaps = 97/761 (12%)
Query: 407 GSPSPASR-TPAR-----PFGSVGRR--SRLAQDFMAQCLRESSPAARPSPEKVPPVLPA 458
GSP P TPA G+VGR+ + A + ES+P A P+ PP
Sbjct: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPA--- 87
Query: 459 PLTPHGTSPVGPPTPPPAPTDP-QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKM 517
S G PP T P ++ + G + A++T
Sbjct: 88 -------SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK--- 137
Query: 518 IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEH 577
E+P+ S S+ R D G + MA A +G P+
Sbjct: 138 ------ATEAPKRSALSAGA-----RRDTSGPTPGTPSPAMARRSRAAGTEVGL-PRPAP 185
Query: 578 QGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSE 637
P P + G +K VS S S+ TE R G R R +
Sbjct: 186 SARPRPPTEGPRKSVS-------SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 638 RADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLS----DASGSDGGRGPEPGV 693
SPA S R P P S+ + G + L P ++ DA+ + G P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 694 EPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLS------RKPLAAPG 747
P S SP P+ P P P+ A+ +G A S PLA P
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATP--PSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 748 DGEGLGQT-----AQPSPPARDGVYVSA-------NGRMVIQLRPGRSPEPDGPAPA-FL 794
A PSPPA + A N V L+ SP P P A F
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 795 RQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAAL 854
S P++ PP+ PP +++ PL + + M + + LAA
Sbjct: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPP----PQAPPPLAAP 469
Query: 855 EARLLSNSVDAECEGGSTPRP----PEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLR 910
+L A + P P + G + ++++ + S + P P P L
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLA 528
Query: 911 AQK-EMSPSPPAAQD---------PGGTALVSAREQSSERQHHP-----LGPTDMGRGEP 955
A ++ PSPPA+ PG VS + P P+ G
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588
Query: 956 VRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATG-AGRLGSRRKPAA 1014
+ + P + S G A P +A+ H + G A L R P A
Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 648
Query: 1015 PPPSPAAREEQSRSSASS---QKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAAD 1071
P P P A S + +GP++ T + P P+ + +A G + +
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708
Query: 1072 GERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTG 1112
++ LG A+ LSR +LA AG G
Sbjct: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGG 749
Score = 51.2 bits (121), Expect = 7e-06
Identities = 113/503 (22%), Positives = 155/503 (30%), Gaps = 96/503 (19%)
Query: 344 PRKKRSQSFTHSPSGDPKADKRRGPT-------PADRDRPSVPAPVQAGGRSSGPQRAGS 396
PRK S + HS + +P RR P+ PA R S P+ + R SGP G+
Sbjct: 196 PRKSVSSASEHSTT-EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGT 253
Query: 397 LKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQ---DFMAQCLRESSPAARPSPEKVP 453
+ P P RP R A + L SP+A PSP P
Sbjct: 254 ---PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
Query: 454 PV--LPA-PLTP--HGTSPVGPPT-----------------PPPAPTDPQLTKARKQEED 491
+ LP+ P TP T+ +G PT PP P L Q
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 492 DSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDD 551
+ + T + A ++ F SP + S P +
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 552 GGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDG 611
+ LQ S P A+P P P +P + + P L
Sbjct: 431 APPSLAAPPLQVPPSPP--ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488
Query: 612 L-----------GRRGGEPEGSLPVR------------MRRRLPQLPSERADSP------ 642
L G+ P SLP+ + L Q+P SP
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 643 -----------AGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEP 691
+GP + PGPP S PS +L S S S + RG +
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
Query: 692 GVE------PQDSRRRSPQEGPTWSRGRRSP----RAPGEPTPASFFIGDQNGDAVLSRK 741
G E P + WSRG P APG P P G + D + +
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 668
Query: 742 PLAAPGDGEGLGQTAQPSPPARD 764
P ++A P+P A D
Sbjct: 669 ETEGP-------ESATPAPGALD 684
Score = 48.1 bits (113), Expect = 6e-05
Identities = 89/347 (25%), Positives = 124/347 (35%), Gaps = 66/347 (19%)
Query: 997 TPEATGAGRL-----GSRRKPAAPPPSPAAREEQSRSSASSQKG-------------PQA 1038
TP A G L GS R P PP +PAA + A +K P++
Sbjct: 16 TPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 1039 LTRSNSLSTPRPTRASRLRRA------RLGDASDTEAADGER--GSLGNP-------EPV 1083
R+ T RP + R RA G S A G G LG E V
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1084 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVEL-----CCASRK 1138
R A +A K S L A R +G GT P A R+ +G V L R
Sbjct: 134 ARGKATEAPKRSALSAGAR-RDTSGPTPGTPSPAMA-RRSRAAGTEVGLPRPAPSARPRP 191
Query: 1139 PTMAEARAVSRKAANTATTTGP------------RQPFSRARSGSARYTSTTQTPRAGSS 1186
PT ++VS + ++ T P ++P SR+ S SA T + R+G S
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA--TPLSSPARSGPS 249
Query: 1187 SRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDG 1246
+R RAP +P P G +Q ++ + + L+
Sbjct: 250 ARGTPRAPA------HPSQPKPKG--LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 1247 DTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPP 1293
S P +L + P+TP S A L +A+ +F PP
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPS--QATTSLGSPTLQATHSFLPSPP 346
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 56.6 bits (135), Expect = 2e-07
Identities = 97/462 (20%), Positives = 141/462 (30%), Gaps = 101/462 (21%)
Query: 354 HSPSGDPKAD-KRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPA 412
+ P G P K +GP P ++P P P G+ GP G K + G P P
Sbjct: 45 NKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQ------GPPPPG 96
Query: 413 SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPT 472
P G R R SP +P P G P GPP
Sbjct: 97 KPQGPPPQGDKSRSPR-------------SPPGKPQ---------GPPPQGGNQPQGPPP 134
Query: 473 PPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSR 532
PP P P K + + + + + + G + P
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPG-------KPQGPPPQGDNKSRSSRSPPGKPQGP---- 183
Query: 533 ASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWV 592
P G++ + + + ++P G P + QG P G Q
Sbjct: 184 -------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ--- 233
Query: 593 SRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSG 652
+ S PG + + G +P+G P + + P P + + P GP +
Sbjct: 234 -------SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQ 284
Query: 653 PGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRG 712
PP+ S+ S P GG P+ P + P +G +G
Sbjct: 285 GPPPQGGSKSRS------SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338
Query: 713 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 772
P P P P Q G SR + PG +G PP ++G
Sbjct: 339 PPPPGKPQGPPP-------QGGSK--SRSARSPPGKPQG--------PPQQEG------- 374
Query: 773 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPP 814
P P P G P + PA P P +PP
Sbjct: 375 -----NNPQGPPPPAGGNP-----QQPQAPPAGQPQGPPRPP 406
Score = 53.5 bits (127), Expect = 1e-06
Identities = 65/270 (24%), Positives = 89/270 (32%), Gaps = 35/270 (12%)
Query: 567 RPLGAAPQAEH--QGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLP 624
+P G PQ + QG P PG P G S + S S PG + + G +P+G P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS-SRSPPGKPQGPPPQGGNQPQGPPP 196
Query: 625 VRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSD 684
+ + P P + + P GP + PP+ D++ Q P
Sbjct: 197 PPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGDNKS------QSARSPPGKPQGPPPQ 248
Query: 685 GGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSR---- 740
GG P+ P + P +G +G P P P P Q G S
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-------QGGSKSRSSRSPP 301
Query: 741 -KPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESF 799
KP P G Q P P G + PG+ P GP P +
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGGSKSRS 358
Query: 800 TKEPASGPPAP---------GKPPHISSHP 820
+ P P P G PP +P
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388
Score = 52.0 bits (123), Expect = 4e-06
Identities = 71/267 (26%), Positives = 94/267 (35%), Gaps = 54/267 (20%)
Query: 565 ASRPLGAAPQAEH--QGLPVP-GSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG---- 617
A P GA PQ + QG P P G P G + + P G +GG
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 90
Query: 618 ------EPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEE 671
+P+G P + R P+ P + P ++ GP PP + P
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-------- 142
Query: 672 LDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGD 731
G + +GP P +PQ P +G SR RSP PG+P G+
Sbjct: 143 -------PPQGGNKPQGPPPPGKPQG----PPPQGDNKSRSSRSP--PGKPQGPPPQGGN 189
Query: 732 Q-NGDAVLSRKPLAAPGDG----EGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEP 786
Q G KP P G +G +P P G S + R PG+ P
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS----PPGK---P 242
Query: 787 DGPAPAFLRQESFTKEPASGPPAPGKP 813
GP P +P PP PGKP
Sbjct: 243 QGPPP------QGGNQPQGPPPPPGKP 263
Score = 51.2 bits (121), Expect = 7e-06
Identities = 98/432 (22%), Positives = 129/432 (29%), Gaps = 104/432 (24%)
Query: 635 PSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVE 694
P + + P GP S GPP QP Q P GG P+ G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQP-----QGPPPPPGKPQGPPPQGGNKPQ-GPP 93
Query: 695 PQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQ-NGDAVLSRKPLAAPGDGEGLG 753
P + P +G SR RSP PG+P G+Q G KP P G
Sbjct: 94 PPGKPQGPPPQGDK-SRSPRSP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150
Query: 754 QTAQPSPPAR-DGVYVSANGRMVIQLRPGRSP--EPDGPAPAFLRQESFTKEPASGPPAP 810
Q P PP + G + + R RSP +P GP P Q P P P
Sbjct: 151 QG--PPPPGKPQGPPPQGDNKS----RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 811 GKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGG 870
PP +GG
Sbjct: 205 --PP-----------------------------------------------------QGG 209
Query: 871 STPR--PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGT 928
+ P+ PP G + S RS P P P + P PP + G
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPG--KPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 929 ALVSAREQSSERQHHPLGPTDMGRGEPVRRSAI----------RRGHRPRGSLDWPSEER 978
+ Q P GP G G R S + G++P+G P + +
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 979 GPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQA 1038
GP P + + P G KP PPP ++ +RS +GP
Sbjct: 327 GPP----PQG---GNKPQGPPPPG--------KPQGPPPQGGSKSRSARSPPGKPQGPPQ 371
Query: 1039 LTRSNSLSTPRP 1050
+N P P
Sbjct: 372 QEGNNPQGPPPP 383
Score = 47.8 bits (112), Expect = 8e-05
Identities = 89/382 (23%), Positives = 121/382 (31%), Gaps = 75/382 (19%)
Query: 344 PRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTE 403
P+ +S+S SP G P+ GP P ++P P P G+ GP G K +
Sbjct: 103 PQGDKSRS-PRSPPGKPQ-----GPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQ--- 151
Query: 404 ERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPH 463
G P P P G RS SP +P P
Sbjct: 152 ---GPPPPGKPQGPPPQGDNKSRS------------SRSPPGKPQ---------GPPPQG 187
Query: 464 GTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFG 523
G P GPP PP P P K + G D + + AR G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQGPPPQGDNKSQSARSPP----G 240
Query: 524 VLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQA--EHQGLP 581
+ P + P G +P G PQ + QG P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPG----------------------KPQGPPPQGGNKPQGPP 278
Query: 582 VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADS 641
PG P G + S S PG + + G +P+G P + + P P + +
Sbjct: 279 PPGKPQGPP-PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNK 335
Query: 642 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPG----VEPQD 697
P GP + PP+ S+ SR P G++ P P +PQ
Sbjct: 336 PQGPPPPGKPQGPPPQGGSK--SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393
Query: 698 SRRRSPQEGPTWSRGRRSPRAP 719
PQ P +G R R P
Sbjct: 394 PPAGQPQGPPRPPQGGRPSRPP 415
Score = 31.6 bits (70), Expect = 6.0
Identities = 30/121 (24%), Positives = 42/121 (34%), Gaps = 16/121 (13%)
Query: 66 EHTPYCEASNPR--PEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPY-- 121
E +P A NP+ P +G +P + P P + G P + QG P
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 122 ---------PERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEV 172
P +P+GP Q + R+P P G P P P P +P
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDK---SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 173 P 173
P
Sbjct: 143 P 143
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/705 (20%), Positives = 227/705 (32%), Gaps = 125/705 (17%)
Query: 571 AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGE---PEGSLPVRM 627
++P+ + G+ + GG +S+ A+ G G R G+ P G+ P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAA--------GSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 628 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFG------QEELDPDSLSDAS 681
+ P R+ + PE S S P PP + + G Q D
Sbjct: 363 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 682 GSDGGRGPEPGVEPQDSR-RRSP-QEGPTWSRGRRSPRAP----------------GEPT 723
P Q S SP GPT R + SP P +P
Sbjct: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ 482
Query: 724 PASFFIGDQNGDAVLSRKPLA----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 779
+S + G G R P+ PG G+ Q PP VS + Q
Sbjct: 483 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
Query: 780 PGRSPEPDGPAP-----------AFLRQESFTKE---PASGPP-APGKPPHISSHPLLQD 824
+ P+P P + Q+ ++E S PP APGKP H
Sbjct: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH--------- 593
Query: 825 LAATRAARMDFHSQDTHLILKETETALAALEARL----------LSNSVDAECEGGSTPR 874
+D +LI +E ++L L + LS++V A GST
Sbjct: 594 -------------EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSA---SGSTSS 637
Query: 875 PPEDALSGDSDVDTASTVSLRSGKSGPSPT-TPQPLRAQKEMSPSPPAAQDPGGTALVSA 933
+ + S ++ L S GPSP+ P+ + + S A PG
Sbjct: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
Query: 934 REQSSERQHHP-LGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDV 990
SE HP L + M P R + R + ++ GP ++ PS +
Sbjct: 698 PGSQSESSSHPALSQSPM----PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 991 MASNHETPEATGAGRLGSRRKPAAP------PPSPAAREEQSRSSASSQKGPQALTRSNS 1044
A ++ +G G + P PP+ + S S G A + +
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 1045 LSTPRPTRASRLRR------------ARLGDASDTEAADGERG--SLGNPEPVGRPAAEQ 1090
+P A L R + + + ++G +G P P A++
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQE 873
Query: 1091 AKKLSRLDILAMPRKRAGSFTG--------TSDPEAAPARTSFSGRSVELCCASRKPTMA 1142
A + R GSF G +S P + P S S + + S P M
Sbjct: 874 AAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMV 933
Query: 1143 EARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSS 1187
+ A S A+ + + P G T ++ SSS
Sbjct: 934 NSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSS 978
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 55.5 bits (132), Expect = 4e-07
Identities = 130/548 (23%), Positives = 197/548 (35%), Gaps = 112/548 (20%)
Query: 571 AAPQAEHQGLPV--PGSPGGQKWVSRWASLADSYS--------DPGLTEDGLGRRGGEPE 620
+ P AE P+ G+PG Q + + + P L ++ G EPE
Sbjct: 68 STPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPE 127
Query: 621 GSLPVR---MRRRLP-----QLPSERADSPAGPESSRR-----SGPGPPELDSEQPS--- 664
V+ +R P QL S +P PE R SG GP + + + +
Sbjct: 128 SGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPEL 187
Query: 665 ---RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPT------------W 709
+L G + L A G + E E +D SPQ+ P
Sbjct: 188 LKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQ 247
Query: 710 SRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVS 769
+ R + PG P + + V + P + P DG +G+ P +V
Sbjct: 248 TAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP-DGPSVGRAKGQDAPLEFTFHVE 306
Query: 770 AN--------------GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAP---GK 812
GR PG PE GP+ +E+ EP+ PA GK
Sbjct: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366
Query: 813 PPHISSHPLLQDLAATRAARMDFHSQD-THLILKETETALAALEARLLSN----SVDAEC 867
P +S P L+ ARM S+D T K+ +T+ + A+ L N S
Sbjct: 367 P--VSRVPQLK-------ARMVSKSKDGTGSDDKKAKTSTRS-SAKTLKNRPCLSPKHPT 416
Query: 868 EGGSTP--RPPEDALSGD--SDVDTASTVSLRSGKSG-----------------PSPTTP 906
G S P +P A+ + S S+V+ R+G SG P P
Sbjct: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
Query: 907 QPLRAQKEM----SPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIR 962
+ Q + +PPA + P +A + +R+ P GP RGEP +S R
Sbjct: 477 PGQKGQANATRIPAKTPPAPKTPPSSA-----TKQVQRRPPPAGPRS-ERGEP-PKSGDR 529
Query: 963 RGHRPRGSLDWP-SEERGPVLAHLPSSD--VMASNHETPEATGAGRLGSRRKPAAPPPSP 1019
G+ GS P S R P L P+ + +A P++ + + R AP P P
Sbjct: 530 SGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK---SRLQTAPVPMP 586
Query: 1020 AAREEQSR 1027
+ +S+
Sbjct: 587 DLKNVKSK 594
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 55.5 bits (132), Expect = 4e-07
Identities = 90/383 (23%), Positives = 129/383 (33%), Gaps = 62/383 (16%)
Query: 712 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQ-----TAQPSPPARDGV 766
G P EP S ++ + LSR PL G E L P PPAR G
Sbjct: 487 GAPEPLDGAEPAKESGLGAEERCPSALSRGPLDEDGTDEALPPPLAPLPPPPPPPARKGS 546
Query: 767 YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGP-PAPGKPPHISSHPLLQDL 825
YVSA RP +E++ PA GP P G ++S L +
Sbjct: 547 YVSA-------FRPVVKDTESIAKLYGSAREAYGAGPARGPGPGAGSGGYVSPDFLSEGS 599
Query: 826 AATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSD 885
++ +A D + D VD E + R P+D D+
Sbjct: 600 SSYNSASPDVDTAD--------------------EPEVDVE-----SNRFPDDE---DAQ 631
Query: 886 VDT-ASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHP 944
+T S S G G PT PP+A G ++ + S R
Sbjct: 632 EETEPSAPSAGGGPDGEQPT-------------GPPSATSSGADGPANSPDGGSPRPRRR 678
Query: 945 LGPTDMGR---GEPVRRSAIRRGHR--PRGSLDWPSEER-GPVLAHLPSSDVMASNHETP 998
LGP GR G+ +RR R P G + E GP+ P+ V A +
Sbjct: 679 LGPPPAGRPAFGDLAAEDLVRRPERSPPSGGGGYELREPCGPLGGPAPAK-VFAPERDEH 737
Query: 999 EATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRR 1058
+ A LG P + +E + S A + ++ S+S P P R
Sbjct: 738 VKSAAVALGPAASYVCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPANTDRGED 797
Query: 1059 ARLGDASDTEAADGERGSLGNPE 1081
D + T + + +L E
Sbjct: 798 GLTLDVTGTHLVEKDIENLAREE 820
Score = 36.2 bits (82), Expect = 0.24
Identities = 63/237 (26%), Positives = 84/237 (35%), Gaps = 58/237 (24%)
Query: 656 PELDSEQ---PSRLFGQEELDPDSLSDASGSDGGR--GPEPGVEP-QDSRRRSPQEGPTW 709
PE+D E P QEE +P + S G DG + GP D SP G
Sbjct: 615 PEVDVESNRFPDDEDAQEETEPSAPSAGGGPDGEQPTGPPSATSSGADGPANSPDGGSPR 674
Query: 710 SRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVS 769
R R P G P GD LAA E L + + SPP+ G Y
Sbjct: 675 PRRRLGPPPAGRPA-----FGD-----------LAA----EDLVRRPERSPPSGGGGY-- 712
Query: 770 ANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATR 829
+LR P GPAPA + AP + H+ S + AA+
Sbjct: 713 -------ELREPCGP-LGGPAPAKVF-------------APERDEHVKSAAVALGPAASY 751
Query: 830 AARMDFH---SQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 883
+ H +D H + ET + + R +S A + G ED L+ D
Sbjct: 752 VCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPANTDRG------EDGLTLD 802
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 55.1 bits (131), Expect = 5e-07
Identities = 123/491 (25%), Positives = 157/491 (31%), Gaps = 75/491 (15%)
Query: 642 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSR 699
P GP S R PGPP Q + E +P ASG G RGP PG D
Sbjct: 180 PMGP-SGPRGLPGPPGAPGPQGFQGPPGEPGEPG----ASGPMGPRGPPGPPGKNGDDGE 234
Query: 700 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLA----APGDGEGLGQT 755
P GR R P P A G + + + A GD G
Sbjct: 235 AGKP--------GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 756 AQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPH 815
+P P +G A G+M + PG P P PA R A+GPP P P
Sbjct: 287 GEPGSPGENG----APGQMGPRGLPGERGRPGAPGPAGARGNDGATG-AAGPPGPTGPAG 341
Query: 816 ISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRP 875
P + S+ + E A A N G+ +P
Sbjct: 342 PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-------GADGQP 394
Query: 876 PEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE 935
+G + A G SGP P K S P A G T + E
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--GPKGNSGEPGAPGSKGDTG--AKGE 450
Query: 936 QSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMAS-- 993
P GP GE +R A R P G P E GP P +D +A
Sbjct: 451 PGPVGVQGPPGPA----GEEGKRGA-RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK 505
Query: 994 ----NHETPEATG-------AGRLGSRRKPAAP-----PPSPAAREEQSRSSASSQKG-- 1035
+P G AGR G P A P SP + + Q G
Sbjct: 506 GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP 565
Query: 1036 -----PQALTRSNSLSTPRPTRASRLRRARLGD--------ASDTEAADGERGSLGNPEP 1082
P A ++ + P P A+ + G+ A DGE G+ G P P
Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAG-EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624
Query: 1083 VGRPAAEQAKK 1093
G PA E+ ++
Sbjct: 625 AG-PAGERGEQ 634
Score = 53.9 bits (128), Expect = 1e-06
Identities = 140/589 (23%), Positives = 171/589 (29%), Gaps = 99/589 (16%)
Query: 570 GAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLT----EDGL-GRRGGE-PEGSL 623
G A QGLP P P G+ + PG + E G G RG + P G
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694
Query: 624 PVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQ-----PSRLFGQEELDPDSLS 678
R P + D+ A + PG + E+ P + + P
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754
Query: 679 DASGSDGGRG-------PEPGVEPQDSRRRSPQ--EGPTWSRGRRSPRA-PGEPTPASFF 728
+ G DG RG P P P D P GPT +RG R PG P PA F
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG-F 813
Query: 729 IGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP---------------PARDGV------- 766
G D K PGD G P P P G
Sbjct: 814 AGPPGADGQPGAK--GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP 871
Query: 767 ----YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTK---EPAS-----GPPAPGKPP 814
+ A GR+ G + P P PA + PA GPP P P
Sbjct: 872 GATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931
Query: 815 HISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR 874
P A T R + E G
Sbjct: 932 GEKGSPGADGPAGAPG----------------TPGPQGIAGQRGVVGLPGQRGERGFPGL 975
Query: 875 PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR 934
P G AS G GP P + +E +P + G+
Sbjct: 976 PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD 1035
Query: 935 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDVMA 992
+ P P G PV A + G R P+ GPV A P+
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPV-GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094
Query: 993 SNHETPEATGAGRLGSR-----RKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLST 1047
ET E G G R + P PP SP EQ S AS GP+ S
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPG---EQGPSGASGPAGPRG--PPGSAGA 1149
Query: 1048 PRPTRASRL--------RRARLGDASDTEAADGERGSLGNPEPVGRPAA 1088
P + L R R GDA G G G P P G P+A
Sbjct: 1150 PGKDGLNGLPGPIGPPGPRGRTGDAGPV----GPPGPPGPPGPPGPPSA 1194
Score = 48.5 bits (114), Expect = 5e-05
Identities = 126/517 (24%), Positives = 155/517 (29%), Gaps = 102/517 (19%)
Query: 613 GRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSE-QPSRLFGQEE 671
G RG P G R +P P P GP PGPP L P +G +E
Sbjct: 118 GPRG--PRGPAGPPGRDGIPGQPG--LPGPPGPPGP----PGPPGLGGNFAPQLSYGYDE 169
Query: 672 LDPDSLS-----DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPAS 726
+S SG G GP PQ + + G + G PR P P
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP--- 226
Query: 727 FFIGDQNGDAVLSRKP-----------------------------------LAAPGDGEG 751
+NGD + KP A GD
Sbjct: 227 ----GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP 282
Query: 752 LGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPG 811
G +P P +G A G+M + PG P P PA R A+GPP P
Sbjct: 283 AGPKGEPGSPGENG----APGQMGPRGLPGERGRPGAPGPAGARGND-GATGAAGPPGPT 337
Query: 812 KPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGS 871
P P + S+ + E A A N G+
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-------GA 390
Query: 872 TPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALV 931
+P +G + A G SGP P K S P A G T
Sbjct: 391 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--GPKGNSGEPGAPGSKGDTG-- 446
Query: 932 SAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVM 991
+ E P GP GE +R A R P G P E GP P +D +
Sbjct: 447 AKGEPGPVGVQGPPGPA----GEEGKRGA-RGEPGPTGLPGPPGERGGPGSRGFPGADGV 501
Query: 992 ASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPT 1051
A P+ AG GS PA P SP E R + G + LT S +P P
Sbjct: 502 AG----PKGP-AGERGS-PGPAGPKGSPG---EAGRPGEAGLPGAKGLT--GSPGSPGP- 549
Query: 1052 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAA 1088
G G G P P G P A
Sbjct: 550 -------------DGKTGPPGPAGQDGRPGPPGPPGA 573
Score = 46.6 bits (109), Expect = 2e-04
Identities = 182/820 (22%), Positives = 242/820 (29%), Gaps = 148/820 (18%)
Query: 358 GDPKADKRRGPT--PADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSP----SP 411
G+ A + GP P +R RP P P A G AG G P +
Sbjct: 293 GENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAK 352
Query: 412 ASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPE---------KVPPVLPAPLTP 462
P P GS G + + + PA P + P + AP P
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412
Query: 463 HGTSPVGPPTP--PPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQ 520
P GP P PP P + D+ + + + E K
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR--- 469
Query: 521 VFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGL 580
G P T P G+R GG R + + P G A + G
Sbjct: 470 --GARGEP------GPTGLPGPPGER-----GGPGSRGFPGADGVAGPKGPAGERGSPGP 516
Query: 581 PVP-GSPG-----GQKWVSRWASLADSYSDPGLTEDGL----------GRRGGEPEGSLP 624
P GSPG G+ + L S PG DG GR G P G
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG--PDGKTGPPGPAGQDGRPG--PPGPPG 572
Query: 625 VRMRRRLPQLPSERADSPAGPESSRRSGPGPP----------ELDSEQPSRLFG----QE 670
R + + P + + ++ R PGPP E ++ P G +
Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632
Query: 671 ELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQE----GPTWSRGRRSPRAPGE----- 721
E P G G GP PG + + P + GP+ +RG R PGE
Sbjct: 633 EQGPAGSPGFQGLPGPAGP-PGEAGKPGEQGVPGDLGAPGPSGARGERG--FPGERGVQG 689
Query: 722 -PTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
P PA R APG+ G P P G A G +Q P
Sbjct: 690 PPGPAG------------PRGANGAPGNDGAKGDAGAPGAPGSQG----APG---LQGMP 730
Query: 781 GRSPEPDGPAPAFLRQESFTK----EPAS----------GPPAPGKPPHISSHPLLQDLA 826
G P P R ++ K P GPP P P A
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790
Query: 827 ---ATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 883
R A D A + DA +G + P P
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850
Query: 884 SDVDTASTVSLRS--GKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 941
+ + G +GP T P A + P P P G + +E
Sbjct: 851 GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEG----- 905
Query: 942 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1001
G G P R P G P+ E+G P +D A TP
Sbjct: 906 ----GKGPRGETGPAGRPGEVGPPGPPG----PAGEKGS-----PGADGPAGAPGTPGPQ 952
Query: 1002 G----------AGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPT 1051
G G+ G R P P PS +Q S AS ++GP L+ P P
Sbjct: 953 GIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGKQGPSGASGERGPPGPMGPPGLAGP-PG 1010
Query: 1052 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQA 1091
+ R + + + G +G G P G P A A
Sbjct: 1011 ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050
Score = 41.2 bits (95), Expect = 0.008
Identities = 63/223 (28%), Positives = 82/223 (36%), Gaps = 36/223 (16%)
Query: 348 RSQSFTHSPSGDPKADKRRGPT-PADR--DR----PSVPA----PVQAGGRSSGPQRAGS 396
R ++ P G P A GP PA + DR P+ PA PV A G +GPQ
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARG-PAGPQGPRG 1094
Query: 397 LKREKTEE-----RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK 451
K E E+ + + P P GS G + A A P +
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154
Query: 452 VPPVLPAPLTPHG-------TSPVGPPTPPPAPTDPQLTKA------RKQEEDDSLSDAG 498
+ LP P+ P G PVGPP PP P P A Q + D G
Sbjct: 1155 LNG-LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213
Query: 499 TYTIETEA-----QDTEVEEARKMIDQVFGVLESPELSRASSA 536
Y +A +D EV+ K + Q + SPE SR + A
Sbjct: 1214 RYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPA 1256
Score = 37.0 bits (84), Expect = 0.14
Identities = 121/534 (22%), Positives = 161/534 (30%), Gaps = 123/534 (23%)
Query: 349 SQSFTHSPSGDPKADKRRGPT-PADRD-RPSVPAPVQAGGRSS-----GPQRAGSLKREK 401
++ T SP G P D + GP PA +D RP P P A G++ GP+ A +
Sbjct: 537 AKGLTGSP-GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595
Query: 402 TEERLGSP----SPASRT----------PARPFGSVGRRSRLAQDFMAQCLRESSP---A 444
E + P PA + PA P G G + + P A
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655
Query: 445 ARPSPEKVPPVLPAPLTPHGTSPVGPPTP-----PPAPTDPQLTKARKQEEDDSLSDAGT 499
+P + VP L AP G P PP P P+ D + DAG
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN-DGAKGDAGA 714
Query: 500 YTIETEA-----QDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRG---------- 544
Q E + G A + + +RG
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774
Query: 545 -----DRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLA 599
D+ ES G A P GA +G P P P G +A
Sbjct: 775 AGAPGDKGESGPSGPAG-----------PTGARGAPGDRGEPGPPGPAG------FAGPP 817
Query: 600 DSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP------ 653
+ PG + G G + + P P P +P + +GP
Sbjct: 818 GADGQPGAKGEP-GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876
Query: 654 -------GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 706
GPP PS G P +G +GG+GP + G
Sbjct: 877 PGAAGRVGPPG-----PSGNAG-----PPGPPGPAGKEGGKGPR------------GETG 914
Query: 707 PTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGV 766
P G P PG P PA G++ + P APG G Q G
Sbjct: 915 PAGRPGEVGP--PGPPGPA----GEKGSPG--ADGPAGAPGTPGPQGIAGQRGVVGLPG- 965
Query: 767 YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHP 820
G PG S EP P+ E GPP P PP ++ P
Sbjct: 966 ---QRGERGFPGLPGPSGEPGKQGPSGASGE-------RGPPGPMGPPGLAGPP 1009
Score = 36.6 bits (83), Expect = 0.19
Identities = 70/302 (23%), Positives = 94/302 (31%), Gaps = 58/302 (19%)
Query: 538 FRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP-VPGSPGGQKWVSRWA 596
F P + DE GG++ P+G + +GLP PG+PG Q +
Sbjct: 159 FAPQLSYGYDEKSTGGIS---------VPGPMGPSGP---RGLPGPPGAPGPQGFQGPPG 206
Query: 597 SLADSYSDPGLTEDGL----GRRGGEPEGSLPVRMRRRLPQLPSERADSPA-----GPES 647
+ + + G G+ G + E P R R P P P G +
Sbjct: 207 EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266
Query: 648 SRR----------SGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQD 697
R +GP P+ + P ++ P L G G GP G D
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP-AGARGND 325
Query: 698 SRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQ 757
G T + G P P P +G G+A P G G +
Sbjct: 326 --------GATGAAGPPGPTGPAGPPGFPGAVG-AKGEA----GPQGPRGSEGPQGVRGE 372
Query: 758 PSPPARDGVYVSANGRMVIQLRPGRSPEPDGP----APAFLRQESFT-KEPASGPPAPGK 812
P PP G A PG +P AP F SGP PG
Sbjct: 373 PGPPGPAGAAGPAG-------NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425
Query: 813 PP 814
PP
Sbjct: 426 PP 427
Score = 34.7 bits (78), Expect = 0.70
Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 2/83 (2%)
Query: 647 SSRRSGPGPPELDSEQ-PSRLFGQE-ELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQ 704
S + PGPP EQ PS G P + A G DG G + P R R+
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173
Query: 705 EGPTWSRGRRSPRAPGEPTPASF 727
GP G P P P A F
Sbjct: 1174 AGPVGPPGPPGPPGPPGPPSAGF 1196
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 54.7 bits (130), Expect = 7e-07
Identities = 150/605 (24%), Positives = 208/605 (34%), Gaps = 96/605 (15%)
Query: 615 RGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDP 674
RGG EG R++ +L GPE + SG P L+S G DP
Sbjct: 2055 RGGLGEGEYAQRLQALRQRLLR------GGPEDGKVSGLRGPLLES------LGGRARDP 2102
Query: 675 DSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNG 734
++ A+ S+ +P +E R Q+ ++S+G PR A I
Sbjct: 2103 -RMARAASSEAAPHHQPPLE-----NRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPV--- 2153
Query: 735 DAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFL 794
A L + L L + AQPS PAR +P+P P A
Sbjct: 2154 -ARLGARRLQESPSLSALSE-AQPSSPARPS-----------------APKPSTPKSA-- 2192
Query: 795 RQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAAL 854
+ T A PPAP + P + + A++ A Q L L + +L
Sbjct: 2193 EPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSL 2252
Query: 855 EARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKE 914
+ LS +G + P P E AS K PS P P+ A+K
Sbjct: 2253 Q---LSGHAQGPSQGPAAP-PSEPKPHAAVFARVASPPPGAPEKRVPSAGGP-PVLAEKA 2307
Query: 915 MSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWP 974
P+ P PG + S SE + + R S + G R
Sbjct: 2308 RVPTVPPR--PGSSLSSSIENLESEAVFE-------AKFKRSRESPLSLGLRLLSRS--R 2356
Query: 975 SEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQK 1034
SEERGP + R PA P R E+SRS +
Sbjct: 2357 SEERGPFRGAEEEDGIY-----------------RPSPAGTPLELVRRPERSRSVQDLRA 2399
Query: 1035 -GPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKK 1093
G L R SLS + R R A+ A + DGE S G G P ++
Sbjct: 2400 VGEPGLVRRLSLSLSQ--RLRRTPPAQRHPAWEARGGDGE-SSEGGSSARGSPVLAMRRR 2456
Query: 1094 LS-RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAA 1152
LS L+ L+ +R+GS + D A SGRS L R+ T +E ++ R
Sbjct: 2457 LSFTLERLSSRLQRSGS---SEDSGGA------SGRSTPLFGRLRRAT-SEGESLRRLGL 2506
Query: 1153 ---NTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 1209
A G P + + A TS + P SR+R R R D P
Sbjct: 2507 PHNQLAAQAGATTPSAESLGSEASATSGSSAP---GESRSRLRWGFSRPRKDKGLSPPNL 2563
Query: 1210 GFIVQ 1214
VQ
Sbjct: 2564 SASVQ 2568
Score = 45.4 bits (106), Expect = 4e-04
Identities = 96/427 (22%), Positives = 147/427 (34%), Gaps = 87/427 (20%)
Query: 875 PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR 934
PP LS SD + L P+ P+PL Q E S S + D
Sbjct: 1913 PPSGGLSSSSDSEEEELEEL--------PSVPRPL--QPEFSGSRVSLTD---------- 1952
Query: 935 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVL-AHLPSSDVMAS 993
+ LG + G P +DW + R P PS + + S
Sbjct: 1953 ---IPTEDEALGTPETGAATP---------------MDWQEQGRAPSQDQEAPSPEALPS 1994
Query: 994 NHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRS--NSLSTPRPT 1051
+ P A + R G R+ + S SA + GP+ L R + S P
Sbjct: 1995 PGQEPAAGASPRRGELRRGS------------SAESALPRAGPRELGRGLHKAASVELPQ 2042
Query: 1052 R------ASRLRRARLGDASDTEAADGERGSL--GNPEPVGRPAAEQAKKLSRLDILAMP 1103
R A+RL R LG+ + R L G PE G+ + + L L A
Sbjct: 2043 RRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPED-GKVSGLRGPLLESLGGRARD 2101
Query: 1104 RKRAGSFTGTSDPEAAPA--------RTSFSGRSVELCCASRKPTMAEARAVSRKAAN-- 1153
+ A + + + P P +SFS E R+ V+R A
Sbjct: 2102 PRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRL 2161
Query: 1154 ----TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 1209
+ + QP S AR + + ++ + ++ + P P+ D EP P
Sbjct: 2162 QESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPE 2221
Query: 1210 GFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSE-PA--------HSASL 1260
V+ ++ A + QTL + AQ I + G G S+ PA H+A
Sbjct: 2222 P--VRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVF 2279
Query: 1261 SNMPSTP 1267
+ + S P
Sbjct: 2280 ARVASPP 2286
Score = 44.3 bits (103), Expect = 9e-04
Identities = 128/508 (25%), Positives = 173/508 (34%), Gaps = 93/508 (18%)
Query: 357 SGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAG--SLKREKTEERLGSP--SPA 412
SG ++ G R P P QA G +GP+ G L R +G+ S
Sbjct: 190 SGQTVLEQEAGSGGGTRRLPGSPRQAQATG--AGPRHLGVEPLVRASRANLVGASWGSED 247
Query: 413 SRTPARP-FGSV-----GRRSRLAQDFMAQCLRESSPAARPS--------PEKVPP---- 454
S + A +GS GR + LR P +P P + PP
Sbjct: 248 SLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQPPPSKSA 307
Query: 455 VLPAPLTPHGT-SPVGPPTPPPA-PTDPQ------------LTKARKQEEDDSLSDAGTY 500
+LP P G SP GPP P A PT P T+ ++ ++ S +
Sbjct: 308 LLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAG 367
Query: 501 TIETEAQDTEVEEARKMIDQVFGVLESPELSRASSAT-----FRPVIRGDRDESDDGG-- 553
T E+ Q T + EA + + SP L RA S F R + SD
Sbjct: 368 TAESRPQ-TPLSEASGRLSALG---RSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAP 423
Query: 554 ----VAQRMALLQEFASRPLGA---APQAEHQGLPVPGSPGGQK--WVSRWASLADSYSD 604
V R A E GA P A + L PGS ++ + + ASL +
Sbjct: 424 LRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQ 483
Query: 605 PGLTED-------GLGRRGGEPEGSLPVR----MRRRLPQLPSERADS-------PAGPE 646
D LGR VR +R L + PS R P+ P+
Sbjct: 484 RSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPK 543
Query: 647 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 706
+SR P + S + G E P S A ++ G GP+ V RR Q
Sbjct: 544 TSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEV------RRRDQFP 597
Query: 707 PTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPP 761
T SR + R+P P A R+P A P GL A P
Sbjct: 598 LTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTL 657
Query: 762 ARDGVYVSANGRMVIQLRPGRSPEPDGP 789
++ A R+ R PE DGP
Sbjct: 658 EKNRAGPEAEKRL------RRGPEEDGP 679
Score = 36.6 bits (83), Expect = 0.19
Identities = 46/186 (24%), Positives = 69/186 (37%), Gaps = 33/186 (17%)
Query: 648 SRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGP 707
+ R+G GP SE ++F + D ++ A+ + P R P + P
Sbjct: 2751 ANRAGQGPFSNSSE---KVFVRGTQDSSAVPSAAHQEAPVTSRPA-------RARPPDSP 2800
Query: 708 TWSRGRRSPRAPGEPTPASFFIGDQN-----GDAVLSRK-----PLAAPGDGEGLGQTAQ 757
T P AP PTP S + + A+ S K P P GL Q A+
Sbjct: 2801 T---SLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGL-QAAR 2856
Query: 758 PSPPARDGVYVSANGRMVIQLR-----PGRSPEPDGPA----PAFLRQESFTKEPASGPP 808
P+ P +V+ + L P +P+ P P ++ + PA PP
Sbjct: 2857 PAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPP 2916
Query: 809 APGKPP 814
AP PP
Sbjct: 2917 APEPPP 2922
Score = 35.4 bits (80), Expect = 0.41
Identities = 111/547 (20%), Positives = 180/547 (32%), Gaps = 71/547 (12%)
Query: 287 GTQSDSEDPLAKAASAAGVPLEA-SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPR 345
G SED L+ A+ G G + + + PQ L ++ + + PR
Sbjct: 240 GASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSV---PQSGLRREEPDLQPQLASEAPR 296
Query: 346 KKRSQSFTHS---PSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 402
+ + S P P+ KR P P + + +P + P+ + ++
Sbjct: 297 RPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGK 356
Query: 403 EERLGSPSPASRTPARP----FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPA 458
+ + PS A +RP + GR S L + SP + ++ L
Sbjct: 357 KSKSSGPSLAGTAESRPQTPLSEASGRLSALGR----------SPRLVRAGSRILDKL-- 404
Query: 459 PLTPHGTSPVGPPTPPPAPTDP--QLTKARKQEEDDSLSDAGTYTIETEAQDT----EVE 512
+ PPAP P L KAR E+ S A T ++ V
Sbjct: 405 QFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVA 464
Query: 513 EARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAA 572
E R++ Q L+ R+ ++ + + + E L A
Sbjct: 465 ERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRA 524
Query: 573 PQAEHQGLPV----PGSPGGQKWVSRWASLADSYSDPGLTEDGLGR------RGGEPEGS 622
P G P P +P + VS A+ S S D GR G G
Sbjct: 525 PSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGE 584
Query: 623 LPVRMRRRLPQLPSERADS---------PAGPESSRRSGPGPPELDSEQPSRLFGQEELD 673
P + RR Q P R+ + P + PP E P++
Sbjct: 585 GPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWA 644
Query: 674 PDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWS----RGRRS--------PRAPGE 721
L A+ G E + RR P+E W RG RS P +P
Sbjct: 645 TPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPEL 704
Query: 722 PTPASFFI--GDQNGDAVLSRKPL----AAPGDGEGLGQTAQPSPPA-----RDGVYVSA 770
+ ++ G++ +A + PL APG L +PP +DG + +
Sbjct: 705 ESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRS 764
Query: 771 NGRMVIQ 777
GR++++
Sbjct: 765 EGRLLLR 771
Score = 35.4 bits (80), Expect = 0.41
Identities = 32/132 (24%), Positives = 49/132 (37%), Gaps = 7/132 (5%)
Query: 358 GDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPA 417
G D R + P P++ + G Q++ S + + E R G A
Sbjct: 2096 GGRARDPRMARAASSEAAPHHQPPLE----NRGLQKSSSFSQGEAEPR-GRHRRAGAPLE 2150
Query: 418 RPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPP-PA 476
P +G R RL + L E+ P++ P P P P T+P P PP P
Sbjct: 2151 IPVARLGAR-RLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQ 2209
Query: 477 PTDPQLTKARKQ 488
P + + R +
Sbjct: 2210 PAQDKAPEPRPE 2221
Score = 33.1 bits (74), Expect = 2.0
Identities = 73/340 (21%), Positives = 109/340 (32%), Gaps = 70/340 (20%)
Query: 166 PSQPPEVPAHEMPTKDAEAGGGGAAP---VVQSHASFTIEFDDCSPGKMKIKDH-ITKFS 221
PSQ E P+ E + GA+P ++ +S P ++ H
Sbjct: 1980 PSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVE 2039
Query: 222 LRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKG 281
L QRR P AT L R G G+ ++ + + R L+G
Sbjct: 2040 LPQRRSPSPGATR---------------------LARGGLGEGEYAQRLQA-LRQRLLRG 2077
Query: 282 HKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDE 341
EDG S PL LE+ G + R R + E + Q +
Sbjct: 2078 GP-EDGKVSGLRGPL----------LESLGGRARDPRMARAASSEAAPHHQPPL------ 2120
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREK 401
+ ++S SF+ + +P+ RR P + +P R +L +
Sbjct: 2121 ENRGLQKSSSFSQGEA-EPRGRHRRAGAPLE-----IPVARLGARRLQESPSLSALSEAQ 2174
Query: 402 TEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP----EKVPP--- 454
+P TP S S Q Q ++ +P RP P + PP
Sbjct: 2175 PSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQA 2234
Query: 455 --VLPAPLTP------------HGTSPVGPPTPPPAPTDP 480
L PLTP H P P PP+ P
Sbjct: 2235 LQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKP 2274
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 54.7 bits (130), Expect = 7e-07
Identities = 71/277 (25%), Positives = 103/277 (37%), Gaps = 45/277 (16%)
Query: 771 NGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA 830
N V++L+P +P P+ P+P FL S T A P PG+ HP ++ A
Sbjct: 616 NAFSVVELKPSVAPAPE-PSPGFLPVNSDTGLVAVPGPVPGQ------HPCGEEATQLPA 668
Query: 831 ARMDFHSQDTHL--ILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDT 888
A F S+ TH I+ ++A + L ++E GG E+ LS ++ +
Sbjct: 669 A---FTSEATHFKPIVLAQNASVARDQPALAQE--ESEERGGQREGEGEEKLSLEAHAGS 723
Query: 889 ASTVSLRSGKSGPSP--TTPQPLRAQKEMS---------PSPPAAQDPGGTALVSAREQS 937
S + GP P P+PL A + P PA Q G ++
Sbjct: 724 PSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVP 783
Query: 938 SERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAH--------LPSSD 989
+ P + G EP+ G RP + GP AH P S
Sbjct: 784 APPTKASALPVEQGPAEPIPPGVASGGLRP--------DALGPTTAHHGPRHPPKPPRSK 835
Query: 990 VMASNHETPEATGAGRLGSR--RKPAAPP--PSPAAR 1022
+ PE GA G R + P + P P PA R
Sbjct: 836 ATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADR 872
Score = 40.8 bits (94), Expect = 0.010
Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 379 PAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCL 438
PA Q G QR G EK + SP+ +TP P G + + A
Sbjct: 693 PALAQEESEERGGQREGE-GEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQ 751
Query: 439 RESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAP 477
R+S+ RP P PP PA P G S P +P PAP
Sbjct: 752 RDSAQG-RPCP---PPQAPAN-QPEGASSAAPGSPVPAP 785
Score = 38.1 bits (87), Expect = 0.064
Identities = 97/397 (24%), Positives = 141/397 (35%), Gaps = 89/397 (22%)
Query: 608 TEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP----PELDSEQP 663
+E+ G+R GE E L + P L + P GP GPGP PE
Sbjct: 700 SEERGGQREGEGEEKLSLEAHAGSPSLKT-----PDGPVP----GPGPQGAAPEPLGASV 750
Query: 664 SRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGP-TWSRGRRSPRAPGEP 722
R Q P + A+ +G PG SP P T + + P EP
Sbjct: 751 QRDSAQGRPCPPPQAPANQPEGASSAAPG---------SPVPAPPTKASALPVEQGPAEP 801
Query: 723 TPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGR 782
P G DA+ P A G P PP R RPG+
Sbjct: 802 IPPGVASGGLRPDAL---GPTTAHH-----GPRHPPKPP-----------RSKATERPGQ 842
Query: 783 SPEPDGPAPAFLRQESFTKEPASGPPAPGKP-------PHISSHPL--------LQDLAA 827
PE G PA R + + P S P P +P P + + PL LQ+ A
Sbjct: 843 EPEGPGATPAGERDD---QSPDSVPERP-RPADRRLCLPCVDASPLPGRTACPSLQE--A 896
Query: 828 TRAARMDFHSQD------THLILKETETALAALEARLLSNSVDAE-CEGGSTPRPPEDAL 880
TR + +F LI+ E AL L ++ + C+ L
Sbjct: 897 TRLIQEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCD-----------L 945
Query: 881 SGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSP--PAAQDPG----GTALVSAR 934
D + + + +G++ PSP+T + +Q E S SP P+++ P G +
Sbjct: 946 YWDEKL-LQNLFKVVNGQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMA 1004
Query: 935 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSL 971
SS P +D+ + + R G RP+ S+
Sbjct: 1005 RTSSRAPCSPTSVSDVD-SDALSRGNFEVGFRPQRSV 1040
Score = 35.8 bits (81), Expect = 0.32
Identities = 55/242 (22%), Positives = 77/242 (31%), Gaps = 30/242 (12%)
Query: 999 EATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRR 1058
E G G RR P P P + + +GP+A LSTP S R
Sbjct: 217 ERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTPVRNGESHSRE 276
Query: 1059 ARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRL------DILAMPRKRAGSFTG 1112
G D E GE + + + R + + RL L +P R S
Sbjct: 277 GLAGLVLDAERTLGEL----DRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLP 332
Query: 1113 TSDPEAAPARTSFSGRSVELCCASRKPTM-------AEARAVSRKAANTATTTGPRQPFS 1165
S+ + R +F R L +P E + A +T GP P S
Sbjct: 333 ISELFSPDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGS 392
Query: 1166 RARSGSARYTSTTQTPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQTAEIAEIARL 1224
+ P S+ + AP PRD + + P I + A E A
Sbjct: 393 PGQ------------PETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAA 440
Query: 1225 SQ 1226
Q
Sbjct: 441 EQ 442
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 54.3 bits (129), Expect = 9e-07
Identities = 144/608 (23%), Positives = 197/608 (32%), Gaps = 85/608 (13%)
Query: 523 GVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPV 582
G + +P S + P +RG + DG ++ A +E + P+G GLP
Sbjct: 404 GHVGAPGPSGPPGSVGAPGLRGTPGK--DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG 461
Query: 583 P------------GSPG--------GQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGS 622
P GSPG G + S DPG+ G G P G
Sbjct: 462 PPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP-GD 520
Query: 623 LPVRMRRRLPQLPSERADSPAGPES-SRRSGPGPPELDSEQPSRLFGQEELDPDSLSDAS 681
R LP P + PAG + S PG L L D +D
Sbjct: 521 KGSPGSRGLPGFPGPQG--PAGRDGLSSLLSPGDINL-------------LAKDVCNDCP 565
Query: 682 GSDGGRGPEPGVEPQDSRRRSP-QEGPTWSRGRRSPRAPGEPTPASFF-----IGDQNGD 735
G PG + P +EG +G P PG P P G++ D
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP--PGLPGPPGIAGPQGSQGERGAD 623
Query: 736 AVLSRK-PLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGPA-- 790
+ +K PG +G P PP DG+ A G IQ PG+ P P GP+
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI-AGAAGPPGIQGSPGKEGPPGPQGPSGL 682
Query: 791 PAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA-ARMDFHSQDTHLILKETET 849
P +E KE G P P P + P L R H+ D+ E+
Sbjct: 683 PGIPGEEG--KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740
Query: 850 ALAALEAR--LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQ 907
L + L D G P+ P + + G+ GPS T Q
Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS-------PGEPGPSGTPGQ 793
Query: 908 PLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMG----RGEPVRRSAIRR 963
+ SP P P G + ++ P P + G RG+P I+
Sbjct: 794 KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP----GIKG 849
Query: 964 GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP---PPSPA 1020
P G P + P H + +M E G G +P P SP+
Sbjct: 850 DKGPPGGKGQPGDPGIP--GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPS 907
Query: 1021 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS--DTEAADGERGSLG 1078
E R + G Q TR L P + + R G + G G +G
Sbjct: 908 M--ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 965
Query: 1079 NPEPVGRP 1086
P GRP
Sbjct: 966 EP---GRP 970
Score = 45.8 bits (107), Expect = 3e-04
Identities = 134/582 (23%), Positives = 170/582 (29%), Gaps = 125/582 (21%)
Query: 540 PVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLA 599
P ++GDR E + G A L P + H +P P G+K
Sbjct: 312 PGLKGDRGEKGEAGPAGPPGL-------PGTTSLFTPHPRMPGEQGPKGEK--------- 355
Query: 600 DSYSDPGLT-EDGLGRRGGE-----PEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP 653
DPGL E GL R GE P G + + P A +P P GP
Sbjct: 356 ---GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA-AGNPGAPGHVGAPGP 411
Query: 654 -GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRG 712
GPP + L G DG RG E G ++ SP GP RG
Sbjct: 412 SGPPG-------------SVGAPGLRGTPGKDGERG-EKGAAGEEG---SP--GPVGPRG 452
Query: 713 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 772
P APG P P ++G+ L P PG G P P
Sbjct: 453 --DPGAPGLPGPPG---KGKDGEPGLRGSP-GLPGPLGTKGDRGAPGIPGS--------- 497
Query: 773 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAAR 832
PG +P +GPP P PP P + L
Sbjct: 498 -------PGSRGDPG--------------IGVAGPPGPSGPPGDKGSPGSRGLPG----- 531
Query: 833 MDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTV 892
F + L+ + LL+ V +C G P GD V
Sbjct: 532 --FPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP----- 584
Query: 893 SLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSER---QHHPLGPTD 949
GK G T + A P PP P G+ + + Q HP P
Sbjct: 585 ----GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640
Query: 950 MG---RGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGA--- 1003
MG P I P G P +E GP PS E E
Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKE-GPPGPQGPSGLPGIPGEEGKEGRDGKPG 699
Query: 1004 --GRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARL 1061
G G +P P P A + P S ++ P +
Sbjct: 700 PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP----GKD 755
Query: 1062 GDASDT-----------EAADGERGSLGNPEPVGRPAAEQAK 1092
GD T +G GS G P P G P + +K
Sbjct: 756 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 797
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 53.9 bits (128), Expect = 1e-06
Identities = 90/336 (26%), Positives = 122/336 (36%), Gaps = 46/336 (13%)
Query: 447 PSPEKVPPVLPAPLT-PHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETE 505
P P V P PL G G P P P+ +K RK E E
Sbjct: 345 PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELS-----------RRE 393
Query: 506 AQDTEV-EEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQ--RMALLQ 562
TE ++ ++++ LE LS+ S T + G D G Q R L
Sbjct: 394 QPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQ----DPGEAVQPCRQPLGA 449
Query: 563 EFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADS------YSDPGLTEDGLGRRG 616
A + E G + GG + ++ S A S +S+ G+ ED GR G
Sbjct: 450 RVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTG 509
Query: 617 GEPEGSLPVRMRRRLPQLPSER-ADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPD 675
+ EG+ P PSE SPAGP + P E +P+ G E +
Sbjct: 510 PK-EGT---------PGSPSETPGPSPAGPAGDEPA-ESPSETPGPRPAGPAGDEPAESP 558
Query: 676 SLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGD 735
S + G G EP P ++ SP GPT SP P PA GD+ +
Sbjct: 559 SETPGPRPAGPAGDEPAESPSETPGPSP-AGPTRDEPAESPSETPGPRPAG-PAGDEPAE 616
Query: 736 A---VLSRKPLAAPGD--GEGLGQTAQPSP--PARD 764
+ +P GD E +T PSP P RD
Sbjct: 617 SPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD 652
Score = 51.2 bits (121), Expect = 7e-06
Identities = 109/435 (25%), Positives = 150/435 (34%), Gaps = 77/435 (17%)
Query: 613 GRRGGEPEGSLPVRMRRRLPQLPSERADSPA---GPESSRRSGPGPPELDSEQPSRLFGQ 669
G R E EGS P P A + GPE S+ G +D R
Sbjct: 306 GSRKVEEEGS---------PGDPDHEASTQGRTCGPEHSKGGG----RVDEGPQPRSVEP 352
Query: 670 EELDP--DSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASF 727
++ P S D +G G PEP + P++S++R + SR + P PG P AS
Sbjct: 353 QDAGPLERSQGDEAGGHGEDRPEP-LSPKESKKRKLE----LSRREQPPTEPG-PQSASE 406
Query: 728 F--IGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPE 785
I LS+ L G + P R + R+ ++R R +
Sbjct: 407 VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPL----GARVADKVRKRRKVD 462
Query: 786 PDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILK 845
A + +G PAP S HP HS++ + +
Sbjct: 463 EGAGDSAAVASGGAQTLALAGSPAP------SGHPKAG------------HSENG--VEE 502
Query: 846 ETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTT 905
+TE E S S TP P +GD ++ S P P
Sbjct: 503 DTEGRTGPKEGTPGSPS--------ETPGPSPAGPAGDEPAESPSET--------PGPRP 546
Query: 906 PQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ-HHPLGPTDMGRGEPVRRSAIRRG 964
P + SPS P G A E SE P GPT R EP + G
Sbjct: 547 AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT---RDEPAESPSETPG 603
Query: 965 HRPRG-----SLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSP 1019
RP G + PSE GP A + S ETP + AG +R +PA +
Sbjct: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG--PTRDEPAKAGEAA 661
Query: 1020 AAREEQSRSSASSQK 1034
++ + SSA S K
Sbjct: 662 ELQDAEVESSAKSGK 676
Score = 45.8 bits (107), Expect = 3e-04
Identities = 44/158 (27%), Positives = 59/158 (37%), Gaps = 31/158 (19%)
Query: 355 SPSGDPKADKRRGPTPADRDRPSVPA---PVQAGGRSSGPQRAGSLKREKTEERLGSPSP 411
SP+G + P+ RP+ PA P ++ + GP+ AG E E +P P
Sbjct: 525 SPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 584
Query: 412 ASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARP----------SPEKVPPVLPAPLT 461
+ P R D A+ E +P RP SP + P P P
Sbjct: 585 SPAGPTR-------------DEPAESPSE-TPGPRPAGPAGDEPAESPSETPG--PRPAG 628
Query: 462 PHGTSPVGPP--TPPPAPTDPQLTKARKQEEDDSLSDA 497
P G P P TP P+P P + K E L DA
Sbjct: 629 PAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Score = 43.5 bits (101), Expect = 0.002
Identities = 48/183 (26%), Positives = 68/183 (37%), Gaps = 25/183 (13%)
Query: 897 GKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPV 956
G++GP TP SP+ PA +P A S P GP EP
Sbjct: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEP-------AESPSETPGPRPAGPAG---DEPA 555
Query: 957 RRSAIRRGHRPRG-----SLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRK 1011
+ G RP G + PSE GP A + S ETP AG G +
Sbjct: 556 ESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGD--E 613
Query: 1012 PA-APPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA 1070
PA +P +P R + G + + P P +R A+ G+A++ + A
Sbjct: 614 PAESPSETPGPR-------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Query: 1071 DGE 1073
+ E
Sbjct: 667 EVE 669
Score = 37.7 bits (86), Expect = 0.083
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 342 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA---PVQAGGRSSGPQRAGSLK 398
D P + S++ SP+G + + P+ RP+ PA P ++ + GP+ AG
Sbjct: 572 DEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG 631
Query: 399 REKTEERLGSPSPASRTPAR 418
E E +P P+ P R
Sbjct: 632 DEPAESPSETPGPSPAGPTR 651
Score = 33.9 bits (76), Expect = 1.2
Identities = 41/147 (27%), Positives = 52/147 (35%), Gaps = 25/147 (17%)
Query: 356 PSGDPKADKRRGPTPADRDRPSVPAPVQAGGRS---------SGPQRAGSLKREKTEERL 406
P G ADK R D A G ++ SG +AG + E+
Sbjct: 446 PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTE 505
Query: 407 GSPSPASRTPARPFGSVG-RRSRLAQDFMAQCLRESSPAARP----------SPEKVPPV 455
G P TP P + G + A D A+ E +P RP SP + P
Sbjct: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSETPG- 563
Query: 456 LPAPLTPHGTSPVGPP--TPPPAPTDP 480
P P P G P P TP P+P P
Sbjct: 564 -PRPAGPAGDEPAESPSETPGPSPAGP 589
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,294,652
Number of Sequences: 37866
Number of extensions: 4783216
Number of successful extensions: 38430
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 1530
Number of HSP's that attempted gapping in prelim test: 25128
Number of HSP's gapped (non-prelim): 12615
length of query: 1484
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1369
effective length of database: 13,892,928
effective search space: 19019418432
effective search space used: 19019418432
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.