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Search of human proteins with 13540569
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo
sapiens]
(441 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens] 908 0.0
gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens] 278 7e-75
gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens] 41 0.002
gi|66773040 phosphatidic acid phosphatase type 2 domain containi... 40 0.003
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 40 0.004
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 39 0.007
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 39 0.007
gi|5803080 macrophage receptor with collagenous structure [Homo ... 39 0.012
gi|195947401 doublesex and mab-3 related transcription factor 2 ... 39 0.012
gi|5729806 doublesex and mab-3 related transcription factor 2 is... 39 0.012
gi|153945850 doublesex and mab-3 related transcription factor 2 ... 39 0.012
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 38 0.016
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 38 0.016
gi|48762934 alpha 2 type I collagen [Homo sapiens] 38 0.021
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 37 0.036
gi|223029457 phosphatidic acid phosphatase type 2 domain contain... 37 0.047
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 37 0.047
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 36 0.061
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 36 0.061
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 36 0.061
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 36 0.061
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 36 0.061
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 36 0.080
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 36 0.080
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 36 0.080
gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo ... 35 0.10
gi|153791755 cyclin domain containing [Homo sapiens] 35 0.10
gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo ... 35 0.14
gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo ... 35 0.14
gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo ... 35 0.14
>gi|13540569 sphingosine-1-phosphate phosphatase 1 [Homo sapiens]
Length = 441
Score = 908 bits (2346), Expect = 0.0
Identities = 441/441 (100%), Positives = 441/441 (100%)
Query: 1 MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQP 60
MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQP
Sbjct: 1 MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQP 60
Query: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQL 120
GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQL
Sbjct: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQL 120
Query: 121 ARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDI 180
ARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDI
Sbjct: 121 ARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDI 180
Query: 181 IRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPC 240
IRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPC
Sbjct: 181 IRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPC 240
Query: 241 WCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHL 300
WCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHL
Sbjct: 241 WCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHL 300
Query: 301 ALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVT 360
ALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVT
Sbjct: 301 ALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVT 360
Query: 361 LFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITY 420
LFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITY
Sbjct: 361 LFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITY 420
Query: 421 GMVGFSITFFVPYIFFFIGIS 441
GMVGFSITFFVPYIFFFIGIS
Sbjct: 421 GMVGFSITFFVPYIFFFIGIS 441
>gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]
Length = 399
Score = 278 bits (711), Expect = 7e-75
Identities = 158/436 (36%), Positives = 241/436 (55%), Gaps = 40/436 (9%)
Query: 7 LAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGP 66
+A+L+ LQD Q VARFQR CG+ P DE GP
Sbjct: 1 MAELLRSLQDSQLVARFQRRCGLFPAP--------DE---------------------GP 31
Query: 67 QPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNW 126
+ G+D + A+ G L A G A LRR + Q V N+
Sbjct: 32 RENGADPTERAARVPG-------VEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNY 84
Query: 127 PLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRP 186
Y LF F LG E+FYI F PF WN+DP + RRL++IWVLVMY+GQ KD+++WPRP
Sbjct: 85 FYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRP 144
Query: 187 ASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVC 246
+SPPVVKLE +EY MPSTHAM+ TAI ++++ T R+QYP + GL++ + +LVC
Sbjct: 145 SSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVC 204
Query: 247 LSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFS 306
LSR+Y GMH++LD++ G L T L++ + YP ID + P +I + L
Sbjct: 205 LSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNY 264
Query: 307 FTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAG--PPITVTLFGK 364
D +S +R DT IL +GAG+ G + + LV P+ ++LP+ PP+T +
Sbjct: 265 PVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPA-ESLPVIQNIPPLTTYMLVL 323
Query: 365 AILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVG 424
+ + +G+V +L++R +++ +++ + F + + ++AR+ +E+E+PY+++TY VG
Sbjct: 324 GLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRN-KEARRRLEIEVPYKFVTYTSVG 382
Query: 425 FSITFFVPYIFFFIGI 440
T FVP + F+G+
Sbjct: 383 ICATTFVPMLHRFLGL 398
>gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]
Length = 357
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/155 (27%), Positives = 66/155 (42%), Gaps = 25/155 (16%)
Query: 143 FYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRP------------ASPP 190
FY+LF P W ++L VG +L+ + V+ +L K I+ RP S P
Sbjct: 43 FYVLF-PIW-FHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVP 100
Query: 191 VVK-LEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQ--------YPLIYGLILIPCW 241
++K V + PS HAM + MV T +Q + + ++ + W
Sbjct: 101 LIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFW 160
Query: 242 CSL--VCLSRIYMGMHSILDIIAGFLYTILILAVF 274
VCLSRIY+ H ++AG L I + F
Sbjct: 161 AVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVTETF 195
>gi|66773040 phosphatidic acid phosphatase type 2 domain containing
2 [Homo sapiens]
Length = 295
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Query: 139 GNELFYILFFPFWIWNLDPLVGRR----LVVIWVLVMYLGQCTKDIIRWPRPASPPVVKL 194
G+ + ++L + + D GR L+ +L + L K ++R RPA +
Sbjct: 141 GHGIPWLLGTLYCLCRSDSWAGREVLMNLLFALLLDLLLVALIKGLVRRRRPAHNQMDMF 200
Query: 195 EVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGM 254
+YS PS HA A +S +L + PL +L+ W ++ LSR+ +G
Sbjct: 201 VTLSVDKYSFPSGHATR--AALMSRFILNHLVLAIPL---RVLVVLWAFVLGLSRVMLGR 255
Query: 255 HSILDIIAGF 264
H++ D+ GF
Sbjct: 256 HNVTDVAFGF 265
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 32 PPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRN 91
PP++ + E + P AG RG G G P P R + + G P R
Sbjct: 880 PPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPP----RRESRTETRWGPRPGSSRR 935
Query: 92 GLAAELGPASPRRAGALRR 110
G+ E A PRRAG +++
Sbjct: 936 GIPPEEPGAPPRRAGPIKK 954
Score = 29.6 bits (65), Expect = 5.7
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 18/80 (22%)
Query: 4 RQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQ---P 60
R+R + R+Q+ ++ A ++L +R DEK AP D RL+ P
Sbjct: 468 RRRREEEERRMQEERRAACAEKL------------KRLDEKFGAP---DKRLKAEPAAPP 512
Query: 61 GAPGGPQPPGSDRNQCPAKP 80
AP P PP + + PA P
Sbjct: 513 AAPSTPAPPPAVPKELPAPP 532
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 14/91 (15%)
Query: 30 EAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGV 89
E PR DR + + AP PR R +PG PG P PPG P G P G+
Sbjct: 130 EQGPR--GDRGDKGEKGAP---GPRGRDGEPGTPGNPGPPG---------PPGPPGPPGL 175
Query: 90 RNGLAAELGPASPRRAGALRRNSLTGEEGQL 120
AA++ +AG + + G G +
Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
Query: 28 GVEAPPRRSADRRE-DEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAP 86
G++ P D+ E E E L G G Q G PG P P G PA P G P
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ-GLPGPPGPSGDQGASGPAGPSGPRGP 1165
Query: 87 NGV--------RNGLAAELGPASPR 103
G NG+ +GP PR
Sbjct: 1166 PGPVGPSGKDGANGIPGPIGPPGPR 1190
Score = 33.5 bits (75), Expect = 0.40
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGP-ASPRRAGAL 108
AG P + G PG PG PPG P P G G+ G E GP P AG
Sbjct: 422 AGAPGIAGA-PGFPGPRGPPGPQGATGPLGPKGQTGEPGIA-GFKGEQGPKGEPGPAGPQ 479
Query: 109 RRNSLTGEEGQ 119
GEEG+
Sbjct: 480 GAPGPAGEEGK 490
Score = 33.1 bits (74), Expect = 0.52
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 60 PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
PGA G PPGS+ N P P G +G + G + GP P RAG G G+
Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGP--PGRAGEPGLQGPAGPPGE 955
Score = 32.7 bits (73), Expect = 0.67
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 8/67 (11%)
Query: 59 QPGAPGGPQPPGSDRNQ----CPAKPDGGGAPNGVRN--GLAAELGPASPRRA-GALRRN 111
+PG PG P P G+ N P GAP G+ G GP P+ A G L
Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP-GIAGAPGFPGPRGPPGPQGATGPLGPK 452
Query: 112 SLTGEEG 118
TGE G
Sbjct: 453 GQTGEPG 459
Score = 32.7 bits (73), Expect = 0.67
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 13/82 (15%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G + PP R A + GD G GAPG P PPGS PA P G
Sbjct: 1041 GADGPPGRDG--------AAGVKGDRGETGAV-GAPGAPGPPGSPG---PAGPTGKQGDR 1088
Query: 88 GVRNGLAAELGPASPRRAGALR 109
G G +GP+ P A ++
Sbjct: 1089 G-EAGAQGPMGPSGPAGARGIQ 1109
Score = 30.4 bits (67), Expect = 3.3
Identities = 19/58 (32%), Positives = 21/58 (36%)
Query: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
GAPG PG D P G P+G+ A P P G LTG G
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG 567
Score = 30.4 bits (67), Expect = 3.3
Identities = 26/91 (28%), Positives = 30/91 (32%), Gaps = 3/91 (3%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G + P S DR P P + G+PG PPG D A G
Sbjct: 1005 GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDG---AAGVKGDRGET 1061
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G A P SP AG + GE G
Sbjct: 1062 GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1092
Score = 30.0 bits (66), Expect = 4.4
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGR--QPGAPGGPQPPGSDRNQCPAKPDGGGA 85
G + PP E+ A +AG RG + G G P G P P G
Sbjct: 741 GAQGPP--GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 798
Query: 86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
NG + E+GP P AG+ GE G+
Sbjct: 799 ANGEK----GEVGPPGP--AGSAGARGAPGERGE 826
Score = 29.6 bits (65), Expect = 5.7
Identities = 17/47 (36%), Positives = 20/47 (42%)
Query: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGA 107
G GGP PG+ + A P G P G + P SP AGA
Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/81 (32%), Positives = 29/81 (35%), Gaps = 15/81 (18%)
Query: 51 GDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVR-----------NGLAAEL 97
G+P G + PGAPG PG D A P G P G R GL
Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671
Query: 98 GPASPRRAGALRRNSLTGEEG 118
GP P G + GE G
Sbjct: 672 GP--PGEGGKPGDQGVPGEAG 690
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/91 (28%), Positives = 28/91 (30%), Gaps = 9/91 (9%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G PP AD + K E AG Q G G P P G P P G P
Sbjct: 834 GFAGPP--GADGQPGAKGEQGEAG-------QKGDAGAPGPQGPSGAPGPQGPTGVTGPK 884
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G R P AG + G G
Sbjct: 885 GARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 14/91 (15%)
Query: 30 EAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGV 89
E PR DR + + AP PR R +PG PG P PPG P G P G+
Sbjct: 61 EQGPR--GDRGDKGEKGAP---GPRGRDGEPGTPGNPGPPG---------PPGPPGPPGL 106
Query: 90 RNGLAAELGPASPRRAGALRRNSLTGEEGQL 120
AA++ +AG + + G G +
Sbjct: 107 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
Query: 28 GVEAPPRRSADRRE-DEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAP 86
G++ P D+ E E E L G G Q G PG P P G PA P G P
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ-GLPGPPGPSGDQGASGPAGPSGPRGP 1096
Query: 87 NGV--------RNGLAAELGPASPR 103
G NG+ +GP PR
Sbjct: 1097 PGPVGPSGKDGANGIPGPIGPPGPR 1121
Score = 33.5 bits (75), Expect = 0.40
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGP-ASPRRAGAL 108
AG P + G PG PG PPG P P G G+ G E GP P AG
Sbjct: 353 AGAPGIAGA-PGFPGPRGPPGPQGATGPLGPKGQTGEPGIA-GFKGEQGPKGEPGPAGPQ 410
Query: 109 RRNSLTGEEGQ 119
GEEG+
Sbjct: 411 GAPGPAGEEGK 421
Score = 33.1 bits (74), Expect = 0.52
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 60 PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
PGA G PPGS+ N P P G +G + G + GP P RAG G G+
Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGP--PGRAGEPGLQGPAGPPGE 886
Score = 32.7 bits (73), Expect = 0.67
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 8/67 (11%)
Query: 59 QPGAPGGPQPPGSDRNQ----CPAKPDGGGAPNGVRN--GLAAELGPASPRRA-GALRRN 111
+PG PG P P G+ N P GAP G+ G GP P+ A G L
Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP-GIAGAPGFPGPRGPPGPQGATGPLGPK 383
Query: 112 SLTGEEG 118
TGE G
Sbjct: 384 GQTGEPG 390
Score = 32.7 bits (73), Expect = 0.67
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 13/82 (15%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G + PP R A + GD G GAPG P PPGS PA P G
Sbjct: 972 GADGPPGRDG--------AAGVKGDRGETGAV-GAPGAPGPPGSPG---PAGPTGKQGDR 1019
Query: 88 GVRNGLAAELGPASPRRAGALR 109
G G +GP+ P A ++
Sbjct: 1020 G-EAGAQGPMGPSGPAGARGIQ 1040
Score = 30.4 bits (67), Expect = 3.3
Identities = 19/58 (32%), Positives = 21/58 (36%)
Query: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
GAPG PG D P G P+G+ A P P G LTG G
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG 498
Score = 30.4 bits (67), Expect = 3.3
Identities = 26/91 (28%), Positives = 30/91 (32%), Gaps = 3/91 (3%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G + P S DR P P + G+PG PPG D A G
Sbjct: 936 GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDG---AAGVKGDRGET 992
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G A P SP AG + GE G
Sbjct: 993 GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023
Score = 30.0 bits (66), Expect = 4.4
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGR--QPGAPGGPQPPGSDRNQCPAKPDGGGA 85
G + PP E+ A +AG RG + G G P G P P G
Sbjct: 672 GAQGPP--GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 729
Query: 86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
NG + E+GP P AG+ GE G+
Sbjct: 730 ANGEK----GEVGPPGP--AGSAGARGAPGERGE 757
Score = 29.6 bits (65), Expect = 5.7
Identities = 17/47 (36%), Positives = 20/47 (42%)
Query: 61 GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGA 107
G GGP PG+ + A P G P G + P SP AGA
Sbjct: 291 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/81 (32%), Positives = 29/81 (35%), Gaps = 15/81 (18%)
Query: 51 GDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVR-----------NGLAAEL 97
G+P G + PGAPG PG D A P G P G R GL
Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602
Query: 98 GPASPRRAGALRRNSLTGEEG 118
GP P G + GE G
Sbjct: 603 GP--PGEGGKPGDQGVPGEAG 621
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/91 (28%), Positives = 28/91 (30%), Gaps = 9/91 (9%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G PP AD + K E AG Q G G P P G P P G P
Sbjct: 765 GFAGPP--GADGQPGAKGEQGEAG-------QKGDAGAPGPQGPSGAPGPQGPTGVTGPK 815
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G R P AG + G G
Sbjct: 816 GARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846
>gi|5803080 macrophage receptor with collagenous structure [Homo
sapiens]
Length = 520
Score = 38.5 bits (88), Expect = 0.012
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 28 GVEAPPRRSADRREDEKAEAP-LAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGG 84
GV PP + + + P LAG P +G Q PG G P PPG+ + AK + G
Sbjct: 268 GVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHP-GAKGEPGS 326
Query: 85 APNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLAR 122
A + R GL P SP G TG +GQ R
Sbjct: 327 AGSPGRAGLPG--SPGSPGATGLKGSKGDTGLQGQQGR 362
Score = 34.3 bits (77), Expect = 0.23
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 51 GDPRLRGRQ-----PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRN--GLAAELGPASPR 103
G P L+G + PGAPG P PP + DG P+G + G+ E G P+
Sbjct: 151 GAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQ 210
Query: 104 RAGALRRNSLTGEEG 118
GA + TG G
Sbjct: 211 --GAPGKQGATGTPG 223
>gi|195947401 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 5/105 (4%)
Query: 31 APPRRSADRREDEK-----AEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGA 85
+PP D +DE +A GD G PG PG P+ G + + P P A
Sbjct: 38 SPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPA 97
Query: 86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYC 130
G R G A PR+ + + G ++ + +C
Sbjct: 98 GTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFC 142
>gi|5729806 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 5/105 (4%)
Query: 31 APPRRSADRREDEK-----AEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGA 85
+PP D +DE +A GD G PG PG P+ G + + P P A
Sbjct: 38 SPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPA 97
Query: 86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYC 130
G R G A PR+ + + G ++ + +C
Sbjct: 98 GTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFC 142
>gi|153945850 doublesex and mab-3 related transcription factor 2
isoform 2 [Homo sapiens]
Length = 561
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 5/105 (4%)
Query: 31 APPRRSADRREDEK-----AEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGA 85
+PP D +DE +A GD G PG PG P+ G + + P P A
Sbjct: 38 SPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPA 97
Query: 86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYC 130
G R G A PR+ + + G ++ + +C
Sbjct: 98 GTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFC 142
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 38.1 bits (87), Expect = 0.016
Identities = 26/60 (43%), Positives = 30/60 (50%), Gaps = 10/60 (16%)
Query: 51 GDPRLRGRQPGAPGGPQPPGSDRNQCPAKP-------DGGGAPNGVR-NGLAAELGPASP 102
GDP + G QPG+PG P PPG + CP P D +GV GLA GPA P
Sbjct: 121 GDPGIPG-QPGSPGSPGPPGICES-CPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178
Score = 37.7 bits (86), Expect = 0.021
Identities = 31/95 (32%), Positives = 36/95 (37%), Gaps = 5/95 (5%)
Query: 28 GVEAPPRRSADRR----EDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGG 83
GV PP S + K E G P G PGA G P PPGS+ N P P G
Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF-PGARGLPGPPGSNGNPGPPGPSGS 898
Query: 84 GAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
+G P SP +G GE+G
Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG 933
Score = 35.4 bits (80), Expect = 0.10
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 24 QRLCGVEAPPRRSADRRED-EKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPD- 81
Q L G PP + E K +A G P +G GAPG PPG P
Sbjct: 641 QGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG-DAGAPGERGPPG-----LAGAPGL 694
Query: 82 -GGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQL 120
GG P G G A P P AG + GE G L
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL 734
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/111 (29%), Positives = 40/111 (36%), Gaps = 30/111 (27%)
Query: 31 APPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGG------PQPPGSDRNQCPAKPDGGG 84
A PR +A E + G P +RG PG+PGG P PPGS P G
Sbjct: 515 AGPRGAAG----EPGRDGVPGGPGMRG-MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569
Query: 85 APNGV-----------------RNGLAAELGPASPRRAGALRRNSLTGEEG 118
P G +NG GP P G +N TG +G
Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERG--GPGGPGPQGPPGKNGETGPQG 618
Score = 32.7 bits (73), Expect = 0.67
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 7/81 (8%)
Query: 28 GVEAPPRRSADRRED-EKAEAPLAGDPRLRGRQPGAPGGPQPPGSD---RNQCPAKPDGG 83
G P D+ E E+ A + G G PGAPG P P G + PA P G
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGN-PGAPGSPGPAGQQGAIGSPGPAGPRGP 1141
Query: 84 GAPNGV--RNGLAAELGPASP 102
P+G ++G + GP P
Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGP 1162
Score = 32.3 bits (72), Expect = 0.88
Identities = 22/53 (41%), Positives = 23/53 (43%), Gaps = 13/53 (24%)
Query: 60 PGAPGGPQPPG--------SDRNQC-PAKPDGGGAPNGVRNGLAAELGPASPR 103
PGAPG P PPG DR + PA P G P G R GP PR
Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGA----PGPQGPR 1091
Score = 31.2 bits (69), Expect = 2.0
Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPR-RAGAL 108
AG P G PG G P PGS Q P G P+G G +GP+ P + G
Sbjct: 176 AGPPGPPG-PPGTSGHPGSPGSPGYQGPPGEPGQAGPSG-PPGPPGAIGPSGPAGKDGES 233
Query: 109 RRNSLTGEEG 118
R GE G
Sbjct: 234 GRPGRPGERG 243
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 8/77 (10%)
Query: 44 KAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDG-GGAPNGVRNGLAAELGPAS- 101
K E AG P G PG G P P G Q P P G G+P G E+GPA
Sbjct: 350 KGEVGPAGSPGSNGA-PGQRGEPGPQGHAGAQGPPGPPGINGSPGG-----KGEMGPAGI 403
Query: 102 PRRAGALRRNSLTGEEG 118
P G + G G
Sbjct: 404 PGAPGLMGARGPPGPAG 420
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 61 GAPGGPQPPG-SDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
G PG P PPG S P P G P G A GP P GA+ + G++G+
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPG--EPGQAGPSGPPGP--PGAIGPSGPAGKDGE 232
Query: 120 LAR 122
R
Sbjct: 233 SGR 235
Score = 30.8 bits (68), Expect = 2.6
Identities = 31/100 (31%), Positives = 35/100 (35%), Gaps = 8/100 (8%)
Query: 26 LCGVEAPPRRSADRREDE---KAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDG 82
L G P R + D + +P R PGAPG P PG PA G
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062
Query: 83 GGAPNGVRNGLAAELGPASPRRA----GALRRNSLTGEEG 118
+G G A GPA R A G TGE G
Sbjct: 1063 DRGESGPA-GPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 6/55 (10%)
Query: 51 GDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPR 103
G P G + PG PG PPG + P P G P G + + GP P+
Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK----GDTGPPGPQ 638
Score = 30.0 bits (66), Expect = 4.4
Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 2/70 (2%)
Query: 51 GDPRLRGR--QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGAL 108
G P +G +PG PG PG D + P P G P G P P AG
Sbjct: 735 GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR 794
Query: 109 RRNSLTGEEG 118
GE G
Sbjct: 795 GSPGERGETG 804
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 38.1 bits (87), Expect = 0.016
Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 7/97 (7%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGR-----QPGAPGGPQPPGSDRNQCPAKPDG 82
G PP D + EK L G+P +RG +PGA G P G D +Q P G
Sbjct: 701 GPMGPPGPKGD--QGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQG 758
Query: 83 GGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQ 119
G+R P P G L G G+
Sbjct: 759 LTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGR 795
Score = 37.0 bits (84), Expect = 0.036
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 10/85 (11%)
Query: 43 EKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRN-----GLAAEL 97
EK E AG+P G PG PG P GS + P P G G+R G+ +
Sbjct: 642 EKGERGAAGEPGPHG-PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDK 700
Query: 98 GPASP----RRAGALRRNSLTGEEG 118
GP P G LTGE G
Sbjct: 701 GPMGPPGPKGDQGEKGPRGLTGEPG 725
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 37.7 bits (86), Expect = 0.021
Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 43 EKAEAPLAGDPRLRGRQ-----PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRN--GLAA 95
EK E L G+ GR PGA G P P G+ ++ A G P G R G
Sbjct: 656 EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERG 715
Query: 96 ELGPASPR----RAGALRRNSLTGEEG 118
E+GPA P AGA + GE G
Sbjct: 716 EVGPAGPNGFAGPAGAAGQPGAKGERG 742
Score = 32.0 bits (71), Expect = 1.1
Identities = 23/59 (38%), Positives = 24/59 (40%), Gaps = 3/59 (5%)
Query: 60 PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
PG PG P P G A P G P G GL GP P G N LTG +G
Sbjct: 255 PGFPGAPGPKGEIGAVGNAGPAGPAGPRG-EVGLPGLSGPVGP--PGNPGANGLTGAKG 310
Score = 30.4 bits (67), Expect = 3.3
Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 11/92 (11%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G PP + R + G P + G PGA G PPG P P G
Sbjct: 766 GPNGPPGPAGSRGD--------GGPPGMTGF-PGAAGRTGPPGPSGISGPPGPPGPAGKE 816
Query: 88 GVRNGLAAELGPAS-PRRAGALRRNSLTGEEG 118
G+R G + GP GA+ GE+G
Sbjct: 817 GLR-GPRGDQGPVGRTGEVGAVGPPGFAGEKG 847
Score = 29.6 bits (65), Expect = 5.7
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 41 EDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAE 96
++E AGD RG + G PG P G D P P G P G+ AA+
Sbjct: 26 QEETVRKGPAGDRGPRGER-GPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQ 80
Score = 29.6 bits (65), Expect = 5.7
Identities = 30/99 (30%), Positives = 36/99 (36%), Gaps = 12/99 (12%)
Query: 28 GVEAPPRRSADRRE----DEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGG 83
G + PP S + + E A G P LRG PG+ G P G P G
Sbjct: 367 GPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRG-SPGSRGLPGADGRAGVMGPPGSRGA 425
Query: 84 GAPNGVR--NGLAAELGPASPRRAGALRRNSLTGEEGQL 120
P GVR NG A P G + L G G +
Sbjct: 426 SGPAGVRGPNGDAGR-----PGEPGLMGPRGLPGSPGNI 459
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 37.0 bits (84), Expect = 0.036
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 4/76 (5%)
Query: 51 GDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVR--NGLAAELGPASPRRAG 106
GD +G + PG G P P G+D + P P G P G G E GP R G
Sbjct: 2695 GDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVG 2754
Query: 107 ALRRNSLTGEEGQLAR 122
A GE G+ R
Sbjct: 2755 APGVPGAPGERGEQGR 2770
Score = 35.8 bits (81), Expect = 0.080
Identities = 23/56 (41%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
Query: 51 GDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAG 106
G+ LRG Q G PG P PG P P G G R A+ P SP RAG
Sbjct: 1260 GEMGLRG-QVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG 1314
Score = 33.9 bits (76), Expect = 0.30
Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 16/84 (19%)
Query: 51 GDPRLRGR----QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRN--------GLAAELG 98
G P +G + GAPG P PGS Q P P G P G R G E G
Sbjct: 1439 GPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERG 1498
Query: 99 PASPRRA----GALRRNSLTGEEG 118
P P + G R G EG
Sbjct: 1499 PPGPAGSRGLPGVAGRPGAKGPEG 1522
Score = 33.5 bits (75), Expect = 0.40
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 7/94 (7%)
Query: 31 APPRRSADRREDEKAEAPLAGDPRLRGR--QPGAPGGPQPPGSDRNQCPAKPDGGGAPNG 88
AP R A ++ ++ + G P L G G PG PG P GAP G
Sbjct: 2258 APGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGG 2317
Query: 89 VRNGLAAELGPASPRRAGALRRNSLTGEEGQLAR 122
+ L E G R R GE+G+ R
Sbjct: 2318 LAGDLVGEPGAKGDRGLPGPR-----GEKGEAGR 2346
Score = 32.3 bits (72), Expect = 0.88
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 10/97 (10%)
Query: 32 PPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGV-- 89
P R + K + L G P RG + G G P P G + PA G P G+
Sbjct: 1721 PGDRGQEGPRGPKGDPGLPGAPGERGIE-GFRGPPGPQGDPGVRGPAGEKGDRGPPGLDG 1779
Query: 90 RNGLAAELGPASPR-------RAGALRRNSLTGEEGQ 119
R+GL + G A P +AG R+ L G G+
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816
Score = 31.6 bits (70), Expect = 1.5
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 43 EKAEAPLAGDPRLRGRQ--PGAPGG---PQPPGSDRNQCPAKPDGGGAPNGVRNGLAAEL 97
E+ A G P L+G + PG GG P PPG+ PA P G P+G++ G E
Sbjct: 2157 ERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQG---PSGLK-GEPGET 2212
Query: 98 GPASPRRAGALRRNSLTGEEG 118
GP G L G G
Sbjct: 2213 GPPGRGLTGPTGAVGLPGPPG 2233
Score = 31.2 bits (69), Expect = 2.0
Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 6/85 (7%)
Query: 37 ADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDG-GGAPNGVRNGLAA 95
AD R A G P G + G+PG P P G + P P G GAP V G
Sbjct: 1303 ADGRPGSPGRAGNPGTPGAPGLK-GSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGG--- 1358
Query: 96 ELGPASPRRAGALRRNSLTGEEGQL 120
GP P R G + G G L
Sbjct: 1359 -EGPGLPGRKGDPGPSGPPGPRGPL 1382
Score = 31.2 bits (69), Expect = 2.0
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 13/79 (16%)
Query: 51 GDPRLRGRQPGAPG--GPQ----PPGSDRNQCPAKPDGGGAP-NGVRNGLAAELGPASPR 103
G+P +RG + G PG GP+ PPGS R + K D G A G + A LGP PR
Sbjct: 2475 GEPGIRG-EDGRPGQEGPRGLTGPPGS-RGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532
Query: 104 RA----GALRRNSLTGEEG 118
A G L G++G
Sbjct: 2533 GAKGDMGERGPRGLDGDKG 2551
Score = 30.4 bits (67), Expect = 3.3
Identities = 28/69 (40%), Positives = 33/69 (47%), Gaps = 9/69 (13%)
Query: 51 GDPRLRGRQPGAPGGPQPPGSD-RNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALR 109
GDP +RG G G PPG D R+ KP G P+G NG A + G P R G
Sbjct: 1758 GDPGVRG-PAGEKGDRGPPGLDGRSGLDGKP-GAAGPSG-PNGAAGKAG--DPGRDGL-- 1810
Query: 110 RNSLTGEEG 118
L GE+G
Sbjct: 1811 -PGLRGEQG 1818
Score = 30.0 bits (66), Expect = 4.4
Identities = 33/95 (34%), Positives = 38/95 (40%), Gaps = 10/95 (10%)
Query: 28 GVEAPPRRSADRRED--EKAEAPLAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGG 83
G PP R D EK E G RG + PG PG P G + + P P G
Sbjct: 1700 GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG- 1758
Query: 84 GAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
GVR G A E G P G R+ L G+ G
Sbjct: 1759 --DPGVR-GPAGEKGDRGP--PGLDGRSGLDGKPG 1788
Score = 29.6 bits (65), Expect = 5.7
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 12/81 (14%)
Query: 40 REDEKAEAPLAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAEL 97
R E+ E G+ +GR PG PG P PPG + G GL+ E
Sbjct: 2056 RPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG--------PGLSGEQ 2107
Query: 98 GPASPRRAGALRRNSLTGEEG 118
GP P GA G++G
Sbjct: 2108 GP--PGLKGAKGEPGSNGDQG 2126
Score = 29.3 bits (64), Expect = 7.5
Identities = 26/87 (29%), Positives = 32/87 (36%), Gaps = 12/87 (13%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLR--GRQPGAPGGPQPPGSDRNQCPAKPDG--- 82
G PP + +K + G P G PG PG P PGS Q P P G
Sbjct: 1386 GPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445
Query: 83 --GGAPNGV-----RNGLAAELGPASP 102
G + +G + G E GP P
Sbjct: 1446 EKGDSEDGAPGLPGQPGSPGEQGPRGP 1472
Score = 29.3 bits (64), Expect = 7.5
Identities = 29/93 (31%), Positives = 33/93 (35%), Gaps = 9/93 (9%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G E PP + R+ EK E GDP + G P P G + PA P G
Sbjct: 1519 GPEGPPGPTG--RQGEKGEPGRPGDPAVVG-----PAVAGPKGEKGDVGPAGPRGATGVQ 1571
Query: 88 GVRN--GLAAELGPASPRRAGALRRNSLTGEEG 118
G R GL P G LTG G
Sbjct: 1572 GERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604
Score = 29.3 bits (64), Expect = 7.5
Identities = 25/77 (32%), Positives = 28/77 (36%), Gaps = 10/77 (12%)
Query: 51 GDPRLRGR-----QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELG----PAS 101
GDP RG + G PG PPG + P G P G R+G E G P
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRG-RDGEVGEKGDEGPPGD 1647
Query: 102 PRRAGALRRNSLTGEEG 118
P G L G G
Sbjct: 1648 PGLPGKAGERGLRGAPG 1664
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 38 DRREDEKAEAPLAGDPRLRGR--QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAA 95
D R+ EK ++ +G G + GAPG P G P P G G P G+
Sbjct: 1853 DGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP-----GVPG 1907
Query: 96 ELGPASPR-RAGALRRNSLTGEEG 118
GP R G+ L GE G
Sbjct: 1908 GTGPKGDRGETGSKGEQGLPGERG 1931
Score = 28.9 bits (63), Expect = 9.7
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 18/79 (22%)
Query: 51 GDPRLRGR--QPGAPG-----GPQ-PPGSDRNQCPAKPDGGGAPNGVRN--GLAAELGPA 100
G+P RG+ PG PG GP+ PG + P P GG G GLA GP
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200
Query: 101 SPRRAGALRRNSLTGEEGQ 119
P + L GE G+
Sbjct: 2201 GP--------SGLKGEPGE 2211
>gi|223029457 phosphatidic acid phosphatase type 2 domain containing
3 [Homo sapiens]
Length = 271
Score = 36.6 bits (83), Expect = 0.047
Identities = 56/235 (23%), Positives = 87/235 (37%), Gaps = 44/235 (18%)
Query: 52 DPRLRGRQPGAPGGPQPPGSD----RNQCPAKPDG----------GGAPNG---VRNGLA 94
+PR GR+ P PP D R Q P+ G A N + ++
Sbjct: 34 EPRSSGRKASGPSAQPPPAGDGARERRQSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMS 93
Query: 95 AELGPASPRRAGALRRNSLTGEEGQLARVSNW---PLYCLFCFGTELGNELFYILFFPFW 151
LG + R A S+ G W + CL T G E+ L
Sbjct: 94 KRLGVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVKSSTLAGQEVLMNL----- 148
Query: 152 IWNLDPLVGRRLVVIWVLVMYLGQCTKDIIR-WPRPASPPVVKLEVFYNSEYSMPSTHAM 210
L+ + + +M + K I R P SP + L+ Y+ P+ HA
Sbjct: 149 -----------LLALLLDIMTVAGVQKLIKRRGPYETSPSL--LDYLTMDIYAFPAGHA- 194
Query: 211 SGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFL 265
A +S L++ PL +L+ W V LSR+ +G H + D+++GF+
Sbjct: 195 -SRAAMVSKFFLSHLVLAVPL---RVLLVLWALCVGLSRVMIGRHHVTDVLSGFV 245
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 36.6 bits (83), Expect = 0.047
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 13/74 (17%)
Query: 43 EKAEAPLAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGV----------- 89
+K E GD ++G + G G P PPGS Q P+ G P G
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154
Query: 90 RNGLAAELGPASPR 103
NGL +GP PR
Sbjct: 1155 LNGLPGPIGPPGPR 1168
Score = 35.8 bits (81), Expect = 0.080
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 24 QRLCGVEAPPRRSADRREDEKAEAP----LAGDPRLRGRQPGAPGGPQPPGSDRNQCPAK 79
Q GVE P + R A P + G P L G PG PG P PPG N P
Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPG-PPGPPGPPGPPGLGGNFAPQL 163
Query: 80 PDGGGAPNGVRNGLAAELGPASPR 103
G + + +GP+ PR
Sbjct: 164 SYGYDEKSTGGISVPGPMGPSGPR 187
Score = 35.8 bits (81), Expect = 0.080
Identities = 32/91 (35%), Positives = 40/91 (43%), Gaps = 13/91 (14%)
Query: 31 APPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPG--SDRNQC-PAKPDGGGAPN 87
+P R + + ++ E AG P G PGAPG P G DR + PA P G P
Sbjct: 1023 SPGRDGSPGAKGDRGETGPAGPPGAPGA-PGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G R GPA P+ G TGE+G
Sbjct: 1082 GAR-------GPAGPQ--GPRGDKGETGEQG 1103
Score = 35.4 bits (80), Expect = 0.10
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 18/106 (16%)
Query: 28 GVEAPPRRSADR-------REDEKAEAPLAGDPRLRGR--------QPGAPGGPQPPGSD 72
GV+ PP + R + K +A G P +G + GA G P P G
Sbjct: 686 GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR 745
Query: 73 RNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
+ P DG +GVR GL +GP P AGA +G G
Sbjct: 746 GDAGPKGADGSPGKDGVR-GLTGPIGPPGP--AGAPGDKGESGPSG 788
Score = 33.1 bits (74), Expect = 0.52
Identities = 31/93 (33%), Positives = 37/93 (39%), Gaps = 19/93 (20%)
Query: 28 GVEAPPRRSADRREDEKAEAP-LAGDPRLRGRQPGAPGGPQPPG--------SDRNQC-- 76
G + P S +R P LAG P GR+ GAPG PG DR +
Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGRE-GAPGAEGSPGRDGSPGAKGDRGETGP 1041
Query: 77 ---PAKPDGGGAPNGV----RNGLAAELGPASP 102
P P GAP V ++G E GPA P
Sbjct: 1042 AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/70 (37%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPAS-PRRAGAL 108
AG P G PGA G PPG N P P G G + G E GPA P G
Sbjct: 868 AGPPGATGF-PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK-GPRGETGPAGRPGEVGPP 925
Query: 109 RRNSLTGEEG 118
GE+G
Sbjct: 926 GPPGPAGEKG 935
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/68 (30%), Positives = 26/68 (38%), Gaps = 1/68 (1%)
Query: 51 GDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRR 110
G P +G GAPG PG + P+ P G G P G + P S GA
Sbjct: 392 GQPGAKGAN-GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE 450
Query: 111 NSLTGEEG 118
G +G
Sbjct: 451 PGPVGVQG 458
Score = 31.2 bits (69), Expect = 2.0
Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 13/78 (16%)
Query: 50 AGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPAS------ 101
AG+P G + PG PG P G D P G P G R E GPA
Sbjct: 589 AGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER----GEQGPAGSPGFQG 644
Query: 102 -PRRAGALRRNSLTGEEG 118
P AG GE+G
Sbjct: 645 LPGPAGPPGEAGKPGEQG 662
Score = 30.8 bits (68), Expect = 2.6
Identities = 26/70 (37%), Positives = 28/70 (40%), Gaps = 7/70 (10%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALR 109
AG P G G PG P G+ P P G P GVR E GP P AGA
Sbjct: 331 AGPPGPTG-PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR----GEPGPPGP--AGAAG 383
Query: 110 RNSLTGEEGQ 119
G +GQ
Sbjct: 384 PAGNPGADGQ 393
Score = 30.8 bits (68), Expect = 2.6
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 4/77 (5%)
Query: 47 APLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAG 106
A AG P G QPGA G P G+ + P P G P G + A P + G
Sbjct: 811 AGFAGPPGADG-QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA---PGAKGARG 866
Query: 107 ALRRNSLTGEEGQLARV 123
+ TG G RV
Sbjct: 867 SAGPPGATGFPGAAGRV 883
Score = 30.4 bits (67), Expect = 3.3
Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 10/80 (12%)
Query: 47 APLAGDPRLRGRQPGAPGGPQPPGSDRNQ------CPAKPDGGGAPNGVRNGLAA--ELG 98
AP PR + G PG P P G+ N P P G P G + A E G
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG 356
Query: 99 PASPRRAGALRRNSLTGEEG 118
P PR G+ + GE G
Sbjct: 357 PQGPR--GSEGPQGVRGEPG 374
Score = 30.4 bits (67), Expect = 3.3
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGV--RNGLAAELGPASPRRAGA 107
AG P +G G+PG P P G PA DG P G G A +G P+ GA
Sbjct: 532 AGLPGAKGLT-GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK--GA 588
Query: 108 LRRNSLTGEEG 118
GE G
Sbjct: 589 AGEPGKAGERG 599
Score = 30.0 bits (66), Expect = 4.4
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 7/67 (10%)
Query: 49 LAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGAPNG-----VRNGLAAELGPAS 101
L G P G Q G PG P PG+ P P G NG + G E GP
Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248
Query: 102 PRRAGAL 108
P+ A L
Sbjct: 249 PQGARGL 255
Score = 29.3 bits (64), Expect = 7.5
Identities = 26/91 (28%), Positives = 32/91 (35%), Gaps = 3/91 (3%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
GV PP +D +A A P + G G PG PA P G
Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
G G+ +LG P +GA GE G
Sbjct: 659 G-EQGVPGDLGAPGP--SGARGERGFPGERG 686
Score = 29.3 bits (64), Expect = 7.5
Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 9/107 (8%)
Query: 15 QDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRN 74
Q P FQ L G PP + + E + GD G GA G PG
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAG-----KPGEQGVPGDLGAPGPS-GARGERGFPGERGV 687
Query: 75 QCPAKPDGGGAPNGV--RNGLAAELG-PASPRRAGALRRNSLTGEEG 118
Q P P G NG +G + G P +P GA + GE G
Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 36.2 bits (82), Expect = 0.061
Identities = 44/154 (28%), Positives = 62/154 (40%), Gaps = 21/154 (13%)
Query: 5 QRLAQLVGRLQDPQKVARFQR--LCGVEAPPRRSADRRE---DEKAEAPL-AGDPRLRGR 58
+R + RL+ RF+ L + A ++S DR+ A+AP A +PR
Sbjct: 36 ERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASAS 95
Query: 59 --QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPAS---------PRRAGA 107
QP G PP ++ + A+PDG G+P R G A G A+ P A
Sbjct: 96 RPQPAPADGADPPPAEEPE--ARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAA 153
Query: 108 LRRN--SLTGEEGQLARVSNWPLYCLFCFGTELG 139
LR N + GQ + P Y F E G
Sbjct: 154 LRSNFERIRKGHGQPGADAEKPFYVNVEFHHERG 187
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 36.2 bits (82), Expect = 0.061
Identities = 44/154 (28%), Positives = 62/154 (40%), Gaps = 21/154 (13%)
Query: 5 QRLAQLVGRLQDPQKVARFQR--LCGVEAPPRRSADRRE---DEKAEAPL-AGDPRLRGR 58
+R + RL+ RF+ L + A ++S DR+ A+AP A +PR
Sbjct: 36 ERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASAS 95
Query: 59 --QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPAS---------PRRAGA 107
QP G PP ++ + A+PDG G+P R G A G A+ P A
Sbjct: 96 RPQPAPADGADPPPAEEPE--ARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAA 153
Query: 108 LRRN--SLTGEEGQLARVSNWPLYCLFCFGTELG 139
LR N + GQ + P Y F E G
Sbjct: 154 LRSNFERIRKGHGQPGADAEKPFYVNVEFHHERG 187
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 36.2 bits (82), Expect = 0.061
Identities = 27/77 (35%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 42 DEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPAS 101
D K E G P RG PG PG P PG + +P G P R G A P
Sbjct: 74 DLKGEPGPPGKPGPRG-PPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGP--PGL 130
Query: 102 PRRAGALRRNSLTGEEG 118
P + G + L GE G
Sbjct: 131 PGKVGPPGQPGLRGEPG 147
Score = 33.1 bits (74), Expect = 0.52
Identities = 30/94 (31%), Positives = 36/94 (38%), Gaps = 11/94 (11%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G PP R + + E PL P +PG PG P P G P P G P
Sbjct: 50 GPVGPPFREG---KGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP-----PGPPGFPGKPG 101
Query: 88 GVRNGLAAELGPASP---RRAGALRRNSLTGEEG 118
+ GL + GPA P R G L G+ G
Sbjct: 102 MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135
Score = 32.3 bits (72), Expect = 0.88
Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
Query: 49 LAGDPRLRGRQP--GAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGP 99
L G+P +RG Q G PG P PG P KP G P G E GP
Sbjct: 142 LRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPG--PPGFQGEPGP 192
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 6/91 (6%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN 87
G P DR E + P P+ G PG PG PG P G G P
Sbjct: 328 GPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPP 387
Query: 88 GVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
GV G+ + GP +G + + GE G
Sbjct: 388 GV-PGIRGDQGP-----SGLAGKPGVPGERG 412
Score = 30.4 bits (67), Expect = 3.3
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 59 QPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVR--NGLAAELGPASPRRAGALRRNSLTGE 116
+PGA G P PPG P G G++ NG+ P +P + GA L G
Sbjct: 174 KPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGP 233
Query: 117 EG 118
G
Sbjct: 234 AG 235
Score = 29.6 bits (65), Expect = 5.7
Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 6/83 (7%)
Query: 40 REDEKAEAPLAGDPRLRGRQ----PGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAA 95
R D+ P G P L G PG PG PG Q P G P G R GL
Sbjct: 149 RGDQGLRGP-PGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDR-GLKG 206
Query: 96 ELGPASPRRAGALRRNSLTGEEG 118
+ G P GA + G G
Sbjct: 207 DNGVGQPGLPGAPGQGGAPGPPG 229
>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
Length = 1484
Score = 36.2 bits (82), Expect = 0.061
Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 18/113 (15%)
Query: 15 QDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRN 74
+DPQ++ Q+ +E + ++ + +GDP+ R+ GP P DR
Sbjct: 322 RDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRR-----GPTPADRDRP 376
Query: 75 QCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWP 127
PA GG +G P+RAG+L+R G + S P
Sbjct: 377 SVPAPVQAGGRSSG-------------PQRAGSLKREKTEERLGSPSPASRTP 416
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
Length = 1554
Score = 36.2 bits (82), Expect = 0.061
Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 18/113 (15%)
Query: 15 QDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRN 74
+DPQ++ Q+ +E + ++ + +GDP+ R+ GP P DR
Sbjct: 392 RDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRR-----GPTPADRDRP 446
Query: 75 QCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWP 127
PA GG +G P+RAG+L+R G + S P
Sbjct: 447 SVPAPVQAGGRSSG-------------PQRAGSLKREKTEERLGSPSPASRTP 486
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 35.8 bits (81), Expect = 0.080
Identities = 27/85 (31%), Positives = 34/85 (40%), Gaps = 7/85 (8%)
Query: 29 VEAPPRRSADRREDEKAEAPLAGDPRLRGR-----QPGAPGGPQPPGSDRNQCPAKPDGG 83
V AP R ++ E+ E AG+ G PGAPG P PPG ++ P
Sbjct: 418 VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSP 477
Query: 84 GAPN--GVRNGLAAELGPASPRRAG 106
G P G + A P SP G
Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRG 502
Score = 33.5 bits (75), Expect = 0.40
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 11/96 (11%)
Query: 28 GVEAPPRRSADRRED-EKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAP 86
G+ P +R D E + G P + G G PG P PPG+D G P
Sbjct: 609 GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM-GPPGNPGPPGADGIA------GAAGP 661
Query: 87 NGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLAR 122
G++ G + GP P+ L + GEEG+ R
Sbjct: 662 PGIQ-GSPGKEGPPGPQGPSGL--PGIPGEEGKEGR 694
Score = 31.2 bits (69), Expect = 2.0
Identities = 20/69 (28%), Positives = 24/69 (34%)
Query: 50 AGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALR 109
A PR G PG PG D + P P G P G + P P +G
Sbjct: 733 APGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPG 792
Query: 110 RNSLTGEEG 118
+ GE G
Sbjct: 793 QKGSKGENG 801
Score = 30.8 bits (68), Expect = 2.6
Identities = 20/57 (35%), Positives = 21/57 (36%), Gaps = 4/57 (7%)
Query: 51 GDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGA 107
GDP L PG PG PG Q P P G G A P +P GA
Sbjct: 356 GDPGL----PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 408
Score = 29.6 bits (65), Expect = 5.7
Identities = 26/99 (26%), Positives = 33/99 (33%), Gaps = 32/99 (32%)
Query: 43 EKAEAPLAGDPRLRGRQ-----------------------PGAPGGPQPPGSDRNQCPAK 79
EK + L G+P L+GR PGA G P PG P+
Sbjct: 354 EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 413
Query: 80 PDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEG 118
P G G+R +P + G GEEG
Sbjct: 414 PPGSVGAPGLR---------GTPGKDGERGEKGAAGEEG 443
Score = 29.6 bits (65), Expect = 5.7
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPRLRGRQ--PGAPGGPQPPGSDRNQCPAKPDGGGA 85
G E PP + + L G P G++ G PG P PG P+G
Sbjct: 669 GKEGPP--------GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 720
Query: 86 PNGVRNGLAAELGPASPR-RAGALRRNSLTGEEG 118
P G + G + G PR +GA+ L G+EG
Sbjct: 721 PPGFK-GHTGDSGAPGPRGESGAM---GLPGQEG 750
Score = 28.9 bits (63), Expect = 9.7
Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 6/71 (8%)
Query: 26 LCGVEAPPRRSADRREDEKAEAPLAGDPRLRGR-----QPGAPGGPQPPGS-DRNQCPAK 79
L G PP E A+ L G P +G PG PG P PPG D +QC
Sbjct: 1001 LRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYF 1060
Query: 80 PDGGGAPNGVR 90
P V+
Sbjct: 1061 ASLAARPGNVK 1071
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 35.8 bits (81), Expect = 0.080
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 4/75 (5%)
Query: 45 AEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRR 104
A A + G P RG PG PG P PGSD P G P G + G + GP P
Sbjct: 21 ALAQIRGPPGERG-PPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPK-GEPGKAGPDGP-- 76
Query: 105 AGALRRNSLTGEEGQ 119
G + LTG +G+
Sbjct: 77 DGKPGIDGLTGAKGE 91
Score = 30.0 bits (66), Expect = 4.4
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 44 KAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPN--GVRNGLAAELGPAS 101
K E G P ++G QPG PG P PG P P G P G+R G + GP
Sbjct: 89 KGEPGPMGIPGVKG-QPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIR-GPKGDPGPDG 146
Query: 102 P 102
P
Sbjct: 147 P 147
Score = 30.0 bits (66), Expect = 4.4
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 43 EKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELG-PAS 101
EK E +G+P +G+Q G G P PG + G P G R GLA G P
Sbjct: 452 EKGEKGESGEPGPKGQQ-GVRGEPGYPGPSGDAGAPGVQGYPGPPGPR-GLAGNRGVPGQ 509
Query: 102 PRRAGALRRNS 112
P R G R++
Sbjct: 510 PGRQGVEGRDA 520
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 35.8 bits (81), Expect = 0.080
Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 11/81 (13%)
Query: 22 RFQRLCGVEAPPRRSADRREDEKAEAPLAGD-----PRLRGRQPGAPGGPQPPGSDRNQC 76
R QR + APP A A AP AG P + R+P P PQPP + Q
Sbjct: 170 RAQRAAPLAAPPPAPAA----PPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225
Query: 77 PAKPDGGGAPNG--VRNGLAA 95
P P P G VR G AA
Sbjct: 226 PPPPQPQPPPEGGAVRAGGAA 246
>gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo
sapiens]
Length = 193
Score = 35.4 bits (80), Expect = 0.10
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 17/77 (22%)
Query: 28 GVEAPPRRSADRREDEKAEAPLAGDPR-----LRGRQPGAPGGPQPPGSDRNQCPAK--- 79
GV P R +RR + +A AG PR RGR A G +PP C ++
Sbjct: 116 GVPTPGNRGGERRGERRAPPRPAGAPRGSPMAARGR---ARGEAEPPALGAGACDSRNQP 172
Query: 80 ------PDGGGAPNGVR 90
P GGGA G R
Sbjct: 173 DSQRTAPPGGGAERGTR 189
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 35.4 bits (80), Expect = 0.10
Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 31 APPRRSADRREDEKAEAPLAGD--PRLRGRQPGAPGGPQPPGSDRNQC------PAKPDG 82
+P R+ R D+ AP+ PRLR +QP P P P D C + DG
Sbjct: 11 SPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDG 70
Query: 83 GGAPNGVRNGLAAELGPASP 102
+P+ R G GPA P
Sbjct: 71 AESPSAARGGSPLP-GPAQP 89
>gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo
sapiens]
Length = 277
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 8/78 (10%)
Query: 40 REDEKAEAPLAG-DPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELG 98
R + P G P+LR RQ G PQ S R A P +P R G
Sbjct: 23 RASSQTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-------G 75
Query: 99 PASPRRAGALRRNSLTGE 116
SP+ AGA+R ++ GE
Sbjct: 76 RGSPKFAGAVRESAEDGE 93
>gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo
sapiens]
Length = 277
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 8/78 (10%)
Query: 40 REDEKAEAPLAG-DPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELG 98
R + P G P+LR RQ G PQ S R A P +P R G
Sbjct: 23 RASSQTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-------G 75
Query: 99 PASPRRAGALRRNSLTGE 116
SP+ AGA+R ++ GE
Sbjct: 76 RGSPKFAGAVRESAEDGE 93
>gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo
sapiens]
Length = 277
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 8/78 (10%)
Query: 40 REDEKAEAPLAG-DPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELG 98
R + P G P+LR RQ G PQ S R A P +P R G
Sbjct: 23 RASSQTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-------G 75
Query: 99 PASPRRAGALRRNSLTGE 116
SP+ AGA+R ++ GE
Sbjct: 76 RGSPKFAGAVRESAEDGE 93
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.145 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,836,452
Number of Sequences: 37866
Number of extensions: 1027215
Number of successful extensions: 8400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 290
Number of HSP's that attempted gapping in prelim test: 5791
Number of HSP's gapped (non-prelim): 2310
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.