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Search of human proteins with 5803092
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5803092 methionyl aminopeptidase 2 [Homo sapiens]
(478 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5803092 methionyl aminopeptidase 2 [Homo sapiens] 987 0.0
gi|124494254 ErbB3-binding protein 1 [Homo sapiens] 107 2e-23
gi|168229156 NFKB activating protein [Homo sapiens] 45 1e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 44 3e-04
gi|4557509 cylicin 2 [Homo sapiens] 44 4e-04
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 43 6e-04
gi|35493853 otoferlin isoform c [Homo sapiens] 42 0.001
gi|35493868 otoferlin isoform b [Homo sapiens] 42 0.001
gi|35493860 otoferlin isoform d [Homo sapiens] 42 0.001
gi|34740331 otoferlin isoform a [Homo sapiens] 42 0.001
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 42 0.001
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 42 0.002
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 42 0.002
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 41 0.003
gi|239746922 PREDICTED: similar to cancer/testis antigen family ... 40 0.004
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 40 0.004
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 40 0.005
gi|55956788 nucleolin [Homo sapiens] 40 0.005
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 40 0.005
gi|4503337 dyskerin isoform 1 [Homo sapiens] 40 0.005
gi|215599015 dyskerin isoform 2 [Homo sapiens] 40 0.005
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006
gi|4507241 structure specific recognition protein 1 [Homo sapiens] 40 0.006
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 40 0.006
gi|223555917 metadherin [Homo sapiens] 39 0.008
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 39 0.008
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 39 0.008
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 39 0.008
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 39 0.008
>gi|5803092 methionyl aminopeptidase 2 [Homo sapiens]
Length = 478
Score = 987 bits (2551), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES 60
MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
Sbjct: 1 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES 60
Query: 61 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI 120
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
Sbjct: 61 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI 120
Query: 121 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR 180
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
Sbjct: 121 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR 180
Query: 181 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT 240
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
Sbjct: 181 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT 240
Query: 241 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV 300
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
Sbjct: 241 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV 300
Query: 301 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV 360
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
Sbjct: 301 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV 360
Query: 361 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL 420
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
Sbjct: 361 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL 420
Query: 421 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY 478
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
Sbjct: 421 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY 478
>gi|124494254 ErbB3-binding protein 1 [Homo sapiens]
Length = 394
Score = 107 bits (267), Expect = 2e-23
Identities = 78/327 (23%), Positives = 144/327 (44%), Gaps = 17/327 (5%)
Query: 153 EEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEK-----LEDCSRKL 207
+E++ A + + ++ + +V + ++ G++++ +CEK +E+ +
Sbjct: 5 DEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIF 64
Query: 208 IKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT-VLQYDDICKIDFGTHISGRIIDCAFT 266
KE + G+AFPT S+NNC H++P D +L+ D+ KID G H+ G I + A T
Sbjct: 65 KKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHT 124
Query: 267 VTFNPKYDTLLKAVK-DATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPI 325
+ T + K D CA +RL G +V E++ ++ PI
Sbjct: 125 FVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKV--AHSFNCTPI 182
Query: 326 RNLNGHSIGQYRIHAGKTV------PIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDME 379
+ H + Q+ I KT+ K E E EVYA++ S+G+G D +
Sbjct: 183 EGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQ 242
Query: 380 CSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLG 439
+ K +++ ++ + + F + F R + E K M +
Sbjct: 243 RTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFE--DEKKARMGVVECAKHE 300
Query: 440 IVDPYPPLCDIKGSYTAQFEHTILLRP 466
++ P+ L + +G + AQF+ T+LL P
Sbjct: 301 LLQPFNVLYEKEGEFVAQFKFTVLLMP 327
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/160 (25%), Positives = 66/160 (41%), Gaps = 18/160 (11%)
Query: 10 SGSHLNGDLDPDDREEGAASTAEEAAKKK----------RRKKKKSKGPSAAGEQEPDKE 59
S H + + + +AST+EE KKK RRKKK SK ++ D +
Sbjct: 157 SDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSD 216
Query: 60 SGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVP 119
S + D +R A + K++++ + KK KKK+ K+ K +D S
Sbjct: 217 SDSETDSSDEDNKRRAKKAKKKEKKKKH--------RSKKYKKKRSKKSRKESSDSSSKE 268
Query: 120 ICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALD 159
+ + + + E P G A TS++ K L+
Sbjct: 269 SQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLN 308
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/155 (21%), Positives = 59/155 (38%), Gaps = 30/155 (19%)
Query: 20 PDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDK 79
P + EE ST + ++ +KKK S+ + ++ K S ++ + ED
Sbjct: 162 PVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSS--------KRKHKKYSEDS 213
Query: 80 ERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPP 139
+ D D E D D KK KKK+K+ K + +Y
Sbjct: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKK----------------------KKHRSKKYKK 251
Query: 140 TQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAE 174
+ ++ + S K++ ++ E W D +A E
Sbjct: 252 KRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.1 bits (105), Expect = 1e-04
Identities = 23/91 (25%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 17 DLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSAL 76
+ + ++ +EG + +K++ KKKK+K E+ +KE + R+ ++
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTK----ETEKRKEKEEEEKKRKRKRKKKKEEE 73
Query: 77 EDKERDEDDEDGDGDGDGATGKKKKKKKKKR 107
E +E +E++E+ + + G+++KKKKK+R
Sbjct: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/89 (22%), Positives = 47/89 (52%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALED 78
+ ++ EE E+ +K++ K+KK K +E ++E + ++ E E+
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 79 KERDEDDEDGDGDGDGATGKKKKKKKKKR 107
+E +E++E + + + +KKKKK++++
Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/99 (23%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSAL-- 76
+ ++ EE +E +K++RK+K+ + +E +K +E R+ +R
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 77 -EDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTD 114
E++E +E++E+ + + + +++KKKKKR K + +
Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 39.7 bits (91), Expect = 0.006
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 10/76 (13%)
Query: 32 EEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGD 91
EE KK++RK+KK K E+E ++E +E R + + R E++E+
Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE---- 111
Query: 92 GDGATGKKKKKKKKKR 107
KKKK+++K +
Sbjct: 112 ------KKKKRRRKTK 121
Score = 35.8 bits (81), Expect = 0.088
Identities = 18/71 (25%), Positives = 38/71 (53%)
Query: 36 KKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGA 95
KKK++KKK+++ E E ++E E ++ + + K+ E ++ + + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 96 TGKKKKKKKKK 106
K+K+KKKK+
Sbjct: 61 KRKRKRKKKKE 71
Score = 29.3 bits (64), Expect = 8.2
Identities = 19/92 (20%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALED 78
+ + R+E + K+K++K+++ + E+E ++E +E + R +
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEER------EEEEEEEEEEKEEEEKEEGRRRKKKK 101
Query: 79 KERDEDDEDGDGDGDGATGKKKKKKKKKRGPK 110
K R +++E+ +KKKK+++K K
Sbjct: 102 KRRRKEEEE----------EKKKKRRRKTKKK 123
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 43.9 bits (102), Expect = 3e-04
Identities = 25/100 (25%), Positives = 53/100 (53%), Gaps = 7/100 (7%)
Query: 28 ASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVD-----EVARQLERSALEDKERD 82
A AE A ++++R+K++ + E+E ++E ++ E +R+ +R ++ERD
Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD 1298
Query: 83 EDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICD 122
D D D + D G+++ ++ KR + ++ S P+ D
Sbjct: 1299 RGDRDRDRERDRERGRERDRRDTKRHSRSRS--RSTPVRD 1336
Score = 33.5 bits (75), Expect = 0.44
Identities = 27/114 (23%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 8 AASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEV 67
++S S GD D + +G ++ ++ R K S+G A E+E + ++
Sbjct: 206 SSSISEEKGDSDDEKPRKGERRSSRV---RQARAAKLSEGSQPAEEEEDQETPSRNLRVR 262
Query: 68 ARQLERSALEDKERD---EDDEDGDGDGDGATGKKKK--KKKKKRGPKVQTDPP 116
A + ++ E++E + EDDE+ +GD +G ++ K+ K+ G ++ P
Sbjct: 263 ADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKP 316
Score = 33.5 bits (75), Expect = 0.44
Identities = 44/168 (26%), Positives = 72/168 (42%), Gaps = 32/168 (19%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
++ E + E+ A+++R +++ + S E+E D++ V E R RS D+ R
Sbjct: 1134 EQREQERAVREQWAEREREMERRERTRS---EREWDRDK---VREGPRSRSRS--RDRRR 1185
Query: 82 DEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEY--PP 139
E K K+KK ++ K Q +PP+ + DL+ K C Y P
Sbjct: 1186 KER-------------AKSKEKKSEKKEKAQEEPPAKLLDDLFRK---TKAAPCIYWLPL 1229
Query: 140 T-----QDGRTAAWRTTSEEKKALDQASEEIWNDFREA-AEAHRQVRK 181
T Q A R EK+ +Q EE +EA E +RQ+ +
Sbjct: 1230 TDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLER 1277
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 26/190 (13%)
Query: 5 EEVAASGSHLNGDLDPDDREEGAASTAEE--AAKKKRRKKKK--SKGPSAAGEQEPDKES 60
E++ A G D + ++ A + +E AKK +K KK +KG +A E E +K
Sbjct: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEK-G 211
Query: 61 GASVDEV-----ARQLERSALE------DKERDEDDEDGDGDGDGATGKKKKKKKKKRGP 109
G D +++ + SA+E D+++DED + GD + KK K+ K+G
Sbjct: 212 GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGK 271
Query: 110 KVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEE-----KKALDQASEE 164
K + P S + +E + T+D + A + T +E K A A ++
Sbjct: 272 KDKKKPSSTD-----SDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKD 326
Query: 165 IWNDFREAAE 174
D ++ A+
Sbjct: 327 AKKDAKKNAK 336
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
D E+G + K+ KK KG +A E E D++ GA D + + + +D
Sbjct: 146 DIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESE-DEKGGAKKDNKKDKKDSNKGKDSAT 204
Query: 82 DEDDEDGDGDGDGATGKKKKKKKKKRGPKVQ 112
+ + E G + D GKK KK K ++Q
Sbjct: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSAIELQ 235
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 2 AGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKK-----KRRKKKKSKGPSAAGEQEP 56
+G E S GD + D E+ ++ E+ ++ KR K+ SK + ++
Sbjct: 696 SGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDG 755
Query: 57 DKESGASVDEVARQLERSALEDKERDEDDE---DGDGDGDGATGKKKKKKKKKRGP 109
+KE+ S + E S++ED D + E + + + T +K+KK K+ R P
Sbjct: 756 EKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTP 811
Score = 30.8 bits (68), Expect = 2.8
Identities = 15/84 (17%), Positives = 36/84 (42%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
+ EE ++ ++ ++ + + + G+ D +S ++ + S LE+K
Sbjct: 680 EEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRT 739
Query: 82 DEDDEDGDGDGDGATGKKKKKKKK 105
+ + G D G+K+ +K K
Sbjct: 740 AKRNSKAKGKSDSEDGEKENEKSK 763
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 33 EAAKKKRRKKKKSKGPSAAGEQEPDKES--------GASVDEVARQLERSA-----LEDK 79
+ A++++ KKKK KG + E+E ES AS+D + QL + LE+K
Sbjct: 607 DVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEK 666
Query: 80 ERDEDDEDGDGDGDG-----ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQE 134
E ++ E G G A ++KKKK + G ++ P + V+PK E
Sbjct: 667 EEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELE 726
Query: 135 CEYPPTQD 142
E+ +D
Sbjct: 727 SEFDNFED 734
Score = 29.3 bits (64), Expect = 8.2
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 15/98 (15%)
Query: 17 DLDPDDREEGAASTAEEAAKKKRRKKKKSKGP-SAAGEQEPDKESGASVDEV---ARQLE 72
++D + +G+ E+A K KKKK++ S G + P+K+ +DE+ ++LE
Sbjct: 668 EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKK-PKIDELKVYPKELE 726
Query: 73 R--SALED--------KERDEDDEDGDGDGDGATGKKK 100
ED + + DDEDG + + G+ K
Sbjct: 727 SEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFK 764
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 33 EAAKKKRRKKKKSKGPSAAGEQEPDKES--------GASVDEVARQLERSA-----LEDK 79
+ A++++ KKKK KG + E+E ES AS+D + QL + LE+K
Sbjct: 530 DVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEK 589
Query: 80 ERDEDDEDGDGDGDG-----ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQE 134
E ++ E G G A ++KKKK + G ++ P + V+PK E
Sbjct: 590 EEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELE 649
Query: 135 CEYPPTQD 142
E+ +D
Sbjct: 650 SEFDNFED 657
Score = 29.3 bits (64), Expect = 8.2
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 15/98 (15%)
Query: 17 DLDPDDREEGAASTAEEAAKKKRRKKKKSKGP-SAAGEQEPDKESGASVDEV---ARQLE 72
++D + +G+ E+A K KKKK++ S G + P+K+ +DE+ ++LE
Sbjct: 591 EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKK-PKIDELKVYPKELE 649
Query: 73 R--SALED--------KERDEDDEDGDGDGDGATGKKK 100
ED + + DDEDG + + G+ K
Sbjct: 650 SEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFK 687
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 33 EAAKKKRRKKKKSKGPSAAGEQEPDKES--------GASVDEVARQLERSA-----LEDK 79
+ A++++ KKKK KG + E+E ES AS+D + QL + LE+K
Sbjct: 530 DVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEK 589
Query: 80 ERDEDDEDGDGDGDG-----ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQE 134
E ++ E G G A ++KKKK + G ++ P + V+PK E
Sbjct: 590 EEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELE 649
Query: 135 CEYPPTQD 142
E+ +D
Sbjct: 650 SEFDNFED 657
Score = 29.3 bits (64), Expect = 8.2
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 15/98 (15%)
Query: 17 DLDPDDREEGAASTAEEAAKKKRRKKKKSKGP-SAAGEQEPDKESGASVDEV---ARQLE 72
++D + +G+ E+A K KKKK++ S G + P+K+ +DE+ ++LE
Sbjct: 591 EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKK-PKIDELKVYPKELE 649
Query: 73 R--SALED--------KERDEDDEDGDGDGDGATGKKK 100
ED + + DDEDG + + G+ K
Sbjct: 650 SEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFK 687
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 33 EAAKKKRRKKKKSKGPSAAGEQEPDKES--------GASVDEVARQLERSA-----LEDK 79
+ A++++ KKKK KG + E+E ES AS+D + QL + LE+K
Sbjct: 1297 DVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEK 1356
Query: 80 ERDEDDEDGDGDGDG-----ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQE 134
E ++ E G G A ++KKKK + G ++ P + V+PK E
Sbjct: 1357 EEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELE 1416
Query: 135 CEYPPTQD 142
E+ +D
Sbjct: 1417 SEFDNFED 1424
Score = 29.3 bits (64), Expect = 8.2
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 15/98 (15%)
Query: 17 DLDPDDREEGAASTAEEAAKKKRRKKKKSKGP-SAAGEQEPDKESGASVDEV---ARQLE 72
++D + +G+ E+A K KKKK++ S G + P+K+ +DE+ ++LE
Sbjct: 1358 EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKK-PKIDELKVYPKELE 1416
Query: 73 R--SALED--------KERDEDDEDGDGDGDGATGKKK 100
ED + + DDEDG + + G+ K
Sbjct: 1417 SEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFK 1454
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 18/117 (15%)
Query: 3 GVEEVAASGSHLNGDLDPDDREEGAAST--------AEEAAKKKRRKKKKSKGPSAAGEQ 54
G EE G GD + ++ +EG E ++ RKK++ G GE+
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 55 EPDKESGASVDEVAR--------QLERSALED--KERDEDDEDGDGDGDGATGKKKK 101
E D+ G + R ++E +E+ ER+E++E+G+G+ + G++++
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Score = 37.0 bits (84), Expect = 0.039
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 21 DDREEGAASTAEEAAKKK-RRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDK 79
+++EEG E + K R++++ +G E E ++E G +E E+
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 80 ERDEDDEDGDGDGDGATGK 98
E +E+ E+G+G+G+ G+
Sbjct: 866 EGEEEGEEGEGEGEEEEGE 884
Score = 37.0 bits (84), Expect = 0.039
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 3 GVEEVAASGSHLNGDLDPDDRE-EGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESG 61
G EE G G+ + ++ E EG EE +++ +++ +G GE+E E G
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGE---GEEE---EEG 1019
Query: 62 ASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQ 112
EV + E++E +E+ E+ + +G+G ++ ++++++ K Q
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070
Score = 36.2 bits (82), Expect = 0.067
Identities = 21/87 (24%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
+ EEG EE + ++ + +G GE E ++E G E + E++E
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEE-GEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 82 DEDDEDGDGDGDGATGKKKKKKKKKRG 108
+ + EDG+G+G+ G+ + ++++ G
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEG 964
Score = 35.8 bits (81), Expect = 0.088
Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 22 DREEGAASTAE-EAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVAR-----QLERSA 75
+ EEG E E +++ K + +G GE+E ++ G +E + E
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEG 895
Query: 76 LEDKERDEDDEDGDGDGDGATGKKKKKKKKKRG 108
E++ E +E+G+G+G+ G+ K +++ + G
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
Score = 35.8 bits (81), Expect = 0.088
Identities = 23/109 (21%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 5 EEVAASGSHLNGDLDPDDRE-EGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGAS 63
E+ G G+ + ++ E EG E ++ + + + GE+E +E G
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 64 VDEVARQLERSALEDK----ERDEDDEDGDGDGDGATGKKKKKKKKKRG 108
E + E E++ E + + E+G+G+G+ G+++ ++++K G
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 14/112 (12%)
Query: 5 EEVAASGSHLNGDLDPDDR--------EEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEP 56
EEV G+ ++R EEG EE + R ++K+ G GE E
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821
Query: 57 DKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRG 108
K E + E E++E + ++E+G+G+ + GK +++ ++ G
Sbjct: 822 GK------GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867
Score = 34.7 bits (78), Expect = 0.20
Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 8/108 (7%)
Query: 3 GVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGA 62
G EE G G+ + ++ EG E +++ K + +G GE E ++ G
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEG------EGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940
Query: 63 SVDEVARQLERSALEDKERDEDDEDGD--GDGDGATGKKKKKKKKKRG 108
D E + E +E + +G+ G+G+G G+ + ++++ G
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Score = 34.3 bits (77), Expect = 0.26
Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 25 EGAASTAEEAAKKKR---RKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
EG AE+ KKR +++K + E+ + E G + + E E++E
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750
Query: 82 DEDDEDGDGDGDGATGKKKK----KKKKKRGPK 110
E + +G+G+ G+++K +KK++R K
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGK 783
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 16 GDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSA 75
G+ + + EEG EE + + + +G E+E ++E E + R
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Query: 76 LEDKERDED--DEDGDGDGDGATGKKKKKKKKKRG 108
E++E +E E G+ + + G++ KK K +G
Sbjct: 1059 REEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG 1093
Score = 30.4 bits (67), Expect = 3.7
Identities = 21/96 (21%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Query: 16 GDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSA 75
G+ + ++EE EE ++K R++ K + E+ ++E G +E + E
Sbjct: 692 GEKELAEKEEWKKRDGEEQ-EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750
Query: 76 LEDKERDEDD-EDGDGDGDGATGKKKKKKKKKRGPK 110
E + ++E + E+ +G+ + G++KK+++ + K
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Score = 30.4 bits (67), Expect = 3.7
Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPD--------------KESGASVDEV 67
D EE E+ +K+R ++ + G GE E + KE G +EV
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEG-EEV 764
Query: 68 ARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRG 108
+ E+ E K+ + ++ G+ +G G+ ++++ + RG
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 13/105 (12%)
Query: 14 LNGDLDP------DDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEV 67
LN L P +D EE + T E KK++K KK + P + KE +
Sbjct: 24 LNNSLPPPHPENEEDPEEDLSET-ETPKLKKKKKPKKPRDPKIPKSKRQKKERML----L 78
Query: 68 ARQLERSALEDKERDEDDEDGD--GDGDGATGKKKKKKKKKRGPK 110
RQL S+ E E E++E+ D +G+ KKKKKK GPK
Sbjct: 79 CRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPK 123
Score = 31.6 bits (70), Expect = 1.7
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 50 AAGEQEPDKESGASVDEVARQLERSALEDK--ERDEDDEDGDGDGDGATGKKKKKKKKKR 107
A+G P S S +E L ++L E +ED E+ + + KKKKK KK R
Sbjct: 2 ASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPR 61
Query: 108 GPKV 111
PK+
Sbjct: 62 DPKI 65
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 29/153 (18%)
Query: 21 DDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKE 80
DD E + ++ + R K K K P A G ++ K+ G+ D E
Sbjct: 212 DDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGS---------------DDE 256
Query: 81 RDEDDEDGDGDG-------DGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQ 133
ED +DGD +G DG++ +++ + K + P+ + P V +
Sbjct: 257 AFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVD-----EQSDSSEES 311
Query: 134 ECEYPPTQDGRTAAWR--TTSEEKKALDQASEE 164
E E PP +D + T +EKK +SEE
Sbjct: 312 EEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEE 344
Score = 32.3 bits (72), Expect = 0.97
Identities = 23/105 (21%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQ-------------EPDKESGASVDEVA 68
D +S+++E + K + ++ +GP EQ E DKE
Sbjct: 272 DYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPT 331
Query: 69 RQLERSALEDKERDEDDEDGDGDGDGATG----KKKKKKKKKRGP 109
Q ++ + E + E+ D D + ++ KKK K++R P
Sbjct: 332 PQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKP 376
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 32 EEAAKKKRRKKKKSKGPSA--AGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGD 89
EE + + ++ K + PS A E+E DKE A +E A + E + E +E E++E G+
Sbjct: 455 EETIEAAKAEEAKDEPPSEGEAEEEEKDKEE-AEEEEAAEEEEAAKEESEEAKEEEEGGE 513
Query: 90 GDGDGATGKKKKKKKKKRG 108
G+ T + ++++KK G
Sbjct: 514 GEEGEETKEAEEEEKKVEG 532
Score = 32.0 bits (71), Expect = 1.3
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 21/96 (21%)
Query: 5 EEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASV 64
+E + G + D ++ EE A+ EEAAK++ E+ ++E G
Sbjct: 468 DEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEE-------------SEEAKEEEEGGEG 514
Query: 65 DEVARQLERSALEDKERDEDDEDGDGDGDGATGKKK 100
+E E KE +E+++ +G G+ KKK
Sbjct: 515 EE--------GEETKEAEEEEKKVEGAGEEQAAKKK 542
>gi|239746922 PREDICTED: similar to cancer/testis antigen family
147, member B1 isoform 2 [Homo sapiens]
Length = 294
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 20 PDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQ--LERSALE 77
P D E A AEE A++K ++ + + +EP KE A+ +E A + E +A
Sbjct: 194 PADLAEMAREPAEEPAEEKPTEEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP 253
Query: 78 DKERDEDDEDGDGDGDGATGKKKKKKKKK 106
++ E D + A GK++K++K+K
Sbjct: 254 EEVTKYQHEKWDEEAQDAAGKEEKEEKEK 282
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 40.4 bits (93), Expect = 0.004
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 4/126 (3%)
Query: 11 GSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQ 70
G H + D + DR + KK +KKK+ G E E G Q
Sbjct: 939 GHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQ 998
Query: 71 LERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFP 130
++S + +++ + D D D ++ KKK+ R P + T V +C+ NG+
Sbjct: 999 KKKSIEKKRKKSKGDSD---ISDEEAAQQSKKKRGPRTPPITTKEELVEMCN-GKNGILE 1054
Query: 131 KGQECE 136
Q+ E
Sbjct: 1055 DSQKKE 1060
Score = 37.0 bits (84), Expect = 0.039
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 15/102 (14%)
Query: 15 NGDLDPDDREEGAA-----STAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVAR 69
N +L+ D+R E +E A+++ R++++ + E+E D+E E R
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER-----EKER 705
Query: 70 QLERSALEDKERDEDDE-----DGDGDGDGATGKKKKKKKKK 106
+LER ++ER+ + E D D D D +++++ ++K
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREK 747
Score = 30.0 bits (66), Expect = 4.8
Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 21/119 (17%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
DRE+ EE +++ R++++ + E+E ++E D+ R+ +R EDK++
Sbjct: 744 DREKEREREREERERERERERERER------ERERERERARERDK-ERERQRD-WEDKDK 795
Query: 82 DEDD--------EDGDGDGDGATGKKKKKKKKKRGPKVQTDPPS-----VPICDLYPNG 127
DD + DG +K KK+ + G P P D Y +G
Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSG 854
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALE- 77
+ D EE + E+ +K K+ K + GE +KE G ++ E +
Sbjct: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKG 193
Query: 78 DKERDEDDEDGDGDG-DGATGKKKKKKKKKRGPKVQTD 114
+ E++E+D GDG + GK+K KK+ + KV+ D
Sbjct: 194 EDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED 231
Score = 37.0 bits (84), Expect = 0.039
Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 21 DDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKE 80
+ +E AA E +K ++ +++ AG+++ D++ E E+ ED +
Sbjct: 114 EKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKG--EDAK 171
Query: 81 RDEDDEDG-DGDGDGATGKKKKKKKKKRGPKVQT 113
ED + G DG G+G GK+K + +K+ + +T
Sbjct: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Score = 34.3 bits (77), Expect = 0.26
Identities = 19/73 (26%), Positives = 35/73 (47%)
Query: 33 EAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDG 92
E A +K +KK++ E+E KE +E + + ++K ++ ED +G+
Sbjct: 106 EDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNE 165
Query: 93 DGATGKKKKKKKK 105
G K+K+ KK
Sbjct: 166 KGEDAKEKEDGKK 178
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/125 (21%), Positives = 50/125 (40%), Gaps = 13/125 (10%)
Query: 2 AGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDK--- 58
AG E+ G +G D + E+G + +E KK K + GE E ++
Sbjct: 144 AGKEDKDEKGEE-DGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDR 202
Query: 59 ---------ESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGP 109
E G + + ED++ ED ++ +G + GK+K+ K++
Sbjct: 203 KETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
Query: 110 KVQTD 114
K + +
Sbjct: 263 KEEDE 267
Score = 32.3 bits (72), Expect = 0.97
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKK--KKSKGPSAAGEQEPDKESGASVDEVARQLERSAL 76
+ +DR+E E K+K KK K K E+E KE +E A + +
Sbjct: 198 EEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLK 257
Query: 77 EDKERDEDDEDGDGDG 92
E++E E+DE + DG
Sbjct: 258 EEEEGKEEDEIKEDDG 273
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 40.0 bits (92), Expect = 0.005
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 24 EEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSAL------- 76
++GAA A+ AK + KK+ + E D+E DE ++E +A+
Sbjct: 124 KKGAAIPAK-GAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182
Query: 77 ----EDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPK 110
ED E DEDDED D D + + ++ + +G K
Sbjct: 183 ASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKK 220
Score = 38.9 bits (89), Expect = 0.010
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 2 AGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESG 61
A ++ AA+ + + D + D+ +E E+ ++++ + +KG AA + P K
Sbjct: 173 AAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAA-KVVPVKAKN 231
Query: 62 ASVDEVARQLERSALEDKERDEDDEDGDGDGDG-------------ATGKKKKKKKKKR 107
+ DE + + ED + DEDDED D + D A GK+KK+ K++
Sbjct: 232 VAEDEDEEEDDED--EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQK 288
Score = 36.6 bits (83), Expect = 0.052
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKS---KGPSAAGEQEPDKESGASVDEVARQLERSA 75
D DD E+ + A E K +K K K + A +++ +++ D+ E
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257
Query: 76 LEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQ 112
ED E +E++E+ + + +KK+ K+K P+ +
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK 294
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKK--------SKGPSAAGEQEPDKESGA---SVDEV 67
DP R + + ++KR++K+K GP+ + + +P+ ES + S E
Sbjct: 650 DPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSES 709
Query: 68 ARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPK 110
S +++++DED+E G G + + K+K KK+ P+
Sbjct: 710 GSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPE 752
Score = 36.6 bits (83), Expect = 0.052
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Query: 10 SGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKS----KGPSAAGEQEPDKESGASVD 65
S S + + +D E+G S +E++ + +RK KK KG +++ ++ D S +S
Sbjct: 714 SSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSES 773
Query: 66 EVARQLERSALE 77
E+ + E LE
Sbjct: 774 EMTSESEEEQLE 785
>gi|4503337 dyskerin isoform 1 [Homo sapiens]
Length = 514
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 27 AASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDE 86
A EAAK +RK++ E E D+ A+ + ++ ++S +DK+ E
Sbjct: 434 APQVVAEAAKTAKRKRES--------ESESDETPPAAPQLIKKEKKKSK-KDKKAKAGLE 484
Query: 87 DGDGDGDGATGKKKKKKKKKRGPKVQ 112
G GDG + KKKKKKK+ +V+
Sbjct: 485 SGAEPGDGDSDTTKKKKKKKKAKEVE 510
>gi|215599015 dyskerin isoform 2 [Homo sapiens]
Length = 509
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 27 AASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDE 86
A EAAK +RK++ E E D+ A+ + ++ ++S +DK+ E
Sbjct: 429 APQVVAEAAKTAKRKRES--------ESESDETPPAAPQLIKKEKKKSK-KDKKAKAGLE 479
Query: 87 DGDGDGDGATGKKKKKKKKKRGPKVQ 112
G GDG + KKKKKKK+ +V+
Sbjct: 480 SGAEPGDGDSDTTKKKKKKKKAKEVE 505
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/88 (26%), Positives = 47/88 (53%), Gaps = 9/88 (10%)
Query: 21 DDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKE 80
+ R+EG E K++R ++K+ + E+E +E G + R+ E + +
Sbjct: 46 ETRKEGKKERESERKKERREREKRKR----EREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 81 RDEDDEDGDGDGDGATGKKKKKKKKKRG 108
R++++++G+ K+KKK+KK+RG
Sbjct: 102 REKENKEGE-----EKEKRKKKEKKERG 124
Score = 36.2 bits (82), Expect = 0.067
Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 23 REEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALED---- 78
R E EE K+K+++KK+ S G++ KE + R+ ++ E
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 79 KERDEDDEDGDGDGDGATGKKKKKKKKKR 107
KER + + G+ + +K++K++KKR
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKR 189
Score = 36.2 bits (82), Expect = 0.067
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 32 EEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGD 91
EE K++ RK++K + GE+E +++ + R+ R KER ++ E +
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-----KERKKERERKERR 206
Query: 92 GDGATGKKKKKKKKKRGPKVQTD 114
KKK+++KK+R QT+
Sbjct: 207 ERKKERKKKEERKKERQKDRQTN 229
Score = 35.4 bits (80), Expect = 0.11
Identities = 18/89 (20%), Positives = 44/89 (49%)
Query: 22 DREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKER 81
+RE EE +++R+K+++ K ++ +++ +E ++ ER + +ER
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 82 DEDDEDGDGDGDGATGKKKKKKKKKRGPK 110
+ + + + +KK++KKK+ K
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKK 220
Score = 35.0 bits (79), Expect = 0.15
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 24 EEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVD----EVARQLERSALEDK 79
++G E KK+RR+K+ +G ++ +K+ E R+ ER E K
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 80 ERDEDDEDGDGDGDGATGKKKKKKK 104
ER+ E+ + + + KK+++K+
Sbjct: 146 ERERKKEEREKERERKERKKRERKQ 170
Score = 32.7 bits (73), Expect = 0.74
Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 8/85 (9%)
Query: 23 REEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERD 82
RE E +K+ R KK+ KG E+E K R+ E E+KE+
Sbjct: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRR--------REKENKEGEEKEKR 115
Query: 83 EDDEDGDGDGDGATGKKKKKKKKKR 107
+ E + GK++++K++++
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERK 140
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/84 (23%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 23 REEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERD 82
RE EE K+K RK++K + + E++ ++E + R+ ER E+++++
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRK-ERKKERERK---ERRERKKERKKKEERKKE 221
Query: 83 EDDEDGDGDGDGATGKKKKKKKKK 106
+ + GK+++K++KK
Sbjct: 222 RQKDRQTNWREKERGKRERKERKK 245
Score = 30.8 bits (68), Expect = 2.8
Identities = 20/84 (23%), Positives = 45/84 (53%), Gaps = 9/84 (10%)
Query: 23 REEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERD 82
+E+ EE +KKRR++K++K GE++ ++ + ++ R++ E KER+
Sbjct: 84 KEKKGERKKEERERKKRRREKENK----EGEEKEKRKK-----KEKKERGRTSKEGKERE 134
Query: 83 EDDEDGDGDGDGATGKKKKKKKKK 106
+E + KK++++K++
Sbjct: 135 RKEERKREERKERERKKEEREKER 158
Score = 29.6 bits (65), Expect = 6.3
Identities = 15/92 (16%), Positives = 43/92 (46%)
Query: 16 GDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSA 75
G + +E + +K+R +KK+ + ++ +E ++ + E+
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
Query: 76 LEDKERDEDDEDGDGDGDGATGKKKKKKKKKR 107
E K+R+ + ++ + + +++KK++KK+
Sbjct: 184 KERKKRERNRKERKKERERKERRERKKERKKK 215
Score = 29.3 bits (64), Expect = 8.2
Identities = 16/87 (18%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 21 DDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKE 80
+ +E G S + ++K +K++ + ++E +KE + ++ ER + +KE
Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER---KERKKRERKQVGEKE 175
Query: 81 RDEDDEDGDGDGDGATGKKKKKKKKKR 107
+ +++ +K++KK+++R
Sbjct: 176 EERKEKERKERKKRERNRKERKKERER 202
>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
Length = 709
Score = 39.7 bits (91), Expect = 0.006
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 34/145 (23%)
Query: 8 AASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKK----KKSKGPSA------------- 50
+AS S GD D D+++ A+ A +K RKK KK K P+A
Sbjct: 500 SASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLN 559
Query: 51 -AGEQEPDKESGASVDEVARQL---------------ERSALEDKERDEDDEDGDGDGDG 94
+ E+ G S+ +++++ +R A ED RD + + +G
Sbjct: 560 ASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKA-EDARRDYEKAMKEYEGGR 618
Query: 95 ATGKKKKKKKKKRGPKVQTDPPSVP 119
K+ K KKK+ KV+ + S P
Sbjct: 619 GESSKRDKSKKKKKVKVKMEKKSTP 643
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 12/106 (11%)
Query: 21 DDREEGAASTAEEAAKK---------KRRKKKKSKGPSAAGEQEPDKESGASVDEVARQL 71
D + E A E+A K+ KR K KK K E++ G+S +RQL
Sbjct: 597 DRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVKVKMEKKSTPSRGSSSKSSSRQL 656
Query: 72 ERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPS 117
S K ++ D G+ + KK+++ + ++ + PPS
Sbjct: 657 SESF---KSKEFVSSDESSSGENKSKKKRRRSEDSEEEELASTPPS 699
Score = 29.6 bits (65), Expect = 6.3
Identities = 33/165 (20%), Positives = 58/165 (35%), Gaps = 19/165 (11%)
Query: 19 DPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALED 78
D D+ + A + K R + + E + G ++VA + + +A
Sbjct: 443 DSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS 502
Query: 79 KERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPS--VPICDLYPNGVFPKGQECE 136
+E D D D +KK+K+ + K+ D S P+ KG++
Sbjct: 503 SSSNEGDSDRD----------EKKRKQLKKAKMAKDRKSRKKPV-------EVKKGKDPN 545
Query: 137 YPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRK 181
P W S EK D I + ++A E + + K
Sbjct: 546 APKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSK 590
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/82 (24%), Positives = 40/82 (48%)
Query: 26 GAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDD 85
G S++++ +KK+RKKK + S++ + S S DE +Q +R + +
Sbjct: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSS 142
Query: 86 EDGDGDGDGATGKKKKKKKKKR 107
+ + + + + KKKKK +
Sbjct: 143 QSSTHESESESKESVKKKKKSK 164
Score = 34.7 bits (78), Expect = 0.20
Identities = 18/92 (19%), Positives = 41/92 (44%)
Query: 23 REEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERD 82
RE+ + + K++R+KK+K K ++ S +S D + ++ K+++
Sbjct: 77 REKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKN 136
Query: 83 EDDEDGDGDGDGATGKKKKKKKKKRGPKVQTD 114
+ + + K+ KKK+ K +T+
Sbjct: 137 RSYKSSQSSTHESESESKESVKKKKKSKDETE 168
Score = 32.7 bits (73), Expect = 0.74
Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 31/121 (25%)
Query: 21 DDREEGAASTAEEAAKKKRRKKKKSKG--PSAAGEQEPDKESGASV-------DEVARQL 71
D + S EE + KRRKKKK++ S + E + ES SV DE ++
Sbjct: 112 DSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK 171
Query: 72 ERSALEDKER----------DEDDEDGDGDGDGATGKKK------------KKKKKKRGP 109
+ +L K + E + D + D KK+ KKKKKK+
Sbjct: 172 DVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK 231
Query: 110 K 110
K
Sbjct: 232 K 232
>gi|223555917 metadherin [Homo sapiens]
Length = 582
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 56 PDKESGASVDEVARQLERSA--LEDKERDEDDEDGDGDGDGATGKKKKKKKKKR 107
P +E G VDE L +S + D ++ DD+ G+G TGK KKKKKKK+
Sbjct: 397 PAEEWGNWVDEERASLLKSQEPIPDDQKVSDDDKEKGEGALPTGKSKKKKKKKK 450
Score = 30.8 bits (68), Expect = 2.8
Identities = 37/152 (24%), Positives = 57/152 (37%), Gaps = 21/152 (13%)
Query: 21 DDRE--EGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALED 78
DD+E EGA T + KKK++KK+ +A +E +KE + + S
Sbjct: 428 DDKEKGEGALPTGKSKKKKKKKKKQGEDNSTAQDTEELEKEIREDL-----PVNTSKTRP 482
Query: 79 KERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI----CDLYPNGVFPKGQE 134
K+ D A K + K P + PSV + D + V P QE
Sbjct: 483 KQEKAFSLKTISTSDPAEVLVKNSQPIKTLPPATSTEPSVILSKSDSDKSSSQVPPILQE 542
Query: 135 CE----------YPPTQDGRTAAWRTTSEEKK 156
+ PP+Q +W + + KK
Sbjct: 543 TDKSKSNTKQNSVPPSQTKSETSWESPKQIKK 574
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 6 EVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVD 65
E A SG+ + + D++EE + + K++ K++ + AG Q + E G D
Sbjct: 239 ERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD 298
Query: 66 EVARQLERSALEDKERDEDDEDGDGD---GDGATGKKKKKKKKKRGPKVQTD 114
E + + L K R E+ E + D +K++K++K PK T+
Sbjct: 299 EKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 6 EVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVD 65
E A SG+ + + D++EE + + K++ K++ + AG Q + E G D
Sbjct: 223 ERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD 282
Query: 66 EVARQLERSALEDKERDEDDEDGDGD---GDGATGKKKKKKKKKRGPKVQTD 114
E + + L K R E+ E + D +K++K++K PK T+
Sbjct: 283 EKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 334
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 12/114 (10%)
Query: 5 EEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKR--------RKKKKSKGPSAAGEQEP 56
EE+A S + + EE A E AAKK ++++ K E+E
Sbjct: 478 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 537
Query: 57 DKESGASVDEV----ARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKK 106
+++ GA D+ + + S E+ E++E + + + +G+ A K++KK ++K
Sbjct: 538 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591
Score = 35.4 bits (80), Expect = 0.11
Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 22/153 (14%)
Query: 4 VEEVAASGSHLNGDLDPDDREEGAAST-AEEAAKKKRRKKKKSKGPSAAGEQEPDKESGA 62
V+E G + ++ +EGA S AEE +K +K +G GE E + E
Sbjct: 520 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE- 578
Query: 63 SVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICD 122
E A E+K+ +E E+ + K +K +K + P VP
Sbjct: 579 ---------EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP--------VPKSP 621
Query: 123 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEK 155
+ G P + P + G++ ++ EEK
Sbjct: 622 VEEKGKSPVPKS---PVEEKGKSPVPKSPVEEK 651
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 12/114 (10%)
Query: 5 EEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKR--------RKKKKSKGPSAAGEQEP 56
EE+A S + + EE A E AAKK ++++ K E+E
Sbjct: 102 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 161
Query: 57 DKESGASVDEV----ARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKK 106
+++ GA D+ + + S E+ E++E + + + +G+ A K++KK ++K
Sbjct: 162 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215
Score = 35.4 bits (80), Expect = 0.11
Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 22/153 (14%)
Query: 4 VEEVAASGSHLNGDLDPDDREEGAAST-AEEAAKKKRRKKKKSKGPSAAGEQEPDKESGA 62
V+E G + ++ +EGA S AEE +K +K +G GE E + E
Sbjct: 144 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE- 202
Query: 63 SVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICD 122
E A E+K+ +E E+ + K +K +K + P VP
Sbjct: 203 ---------EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP--------VPKSP 245
Query: 123 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEK 155
+ G P + P + G++ ++ EEK
Sbjct: 246 VEEKGKSPVPKS---PVEEKGKSPVPKSPVEEK 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,666,202
Number of Sequences: 37866
Number of extensions: 1034387
Number of successful extensions: 9275
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 415
Number of HSP's that attempted gapping in prelim test: 5798
Number of HSP's gapped (non-prelim): 2574
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.