Guide to the Human Genome
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Name: NEFL Sequence: fasta or formatted (543aa) NCBI GI: 105990539
Description:

neurofilament, light polypeptide 68kDa

Referenced in:

Cytoskeleton
Neurons

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.0         60           2
 C cysteine            0.2          1           1
 D aspartate           4.2         23           1
 E glutamate          18.2         99           4
 F phenylalanine       1.8         10           1
 G glycine             3.7         20           2
 H histidine           0.9          5           1
 I isoleucine          3.5         19           1
 K lysine              7.0         38           3
 L leucine             8.8         48           2
 M methionine          2.0         11           1
 N asparagine          2.6         14           1
 P proline             1.7          9           2
 Q glutamine           5.2         28           2
 R arginine            6.4         35           2
 S serine             10.5         57           4
 T threonine           4.1         22           2
 V valine              4.1         22           1
 W tryptophan          0.2          1           1
 Y tyrosine            3.9         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neurofilament, light polypeptide 68kDa 
NEFM                  0.376   neurofilament, medium polypeptide 150kDa isoform 1 ...
INA                   0.371   internexin neuronal intermediate filament protein, a...
VIM                   0.329   vimentin 
DES                   0.322   desmin 
PRPH                  0.311   peripherin 
GFAP                  0.292   glial fibrillary acidic protein isoform 2 
GFAP                  0.292   glial fibrillary acidic protein isoform 1 
NEFH                  0.279   neurofilament, heavy polypeptide 200kDa 
KRT8                  0.217   keratin 8 
KRT7                  0.206   keratin 7 
KRT5                  0.204   keratin 5 
KRT6A                 0.200   keratin 6A 
KRT6C                 0.200   keratin 6C 
KRT6B                 0.198   keratin 6B 
KRT75                 0.197   keratin 75 
KRT84                 0.195   keratin, hair, basic, 4 
KRT76                 0.188   keratin 76 
KRT85                 0.188   keratin 85 
KRT73                 0.187   keratin 73 
KRT3                  0.186   keratin 3 
KRT4                  0.186   keratin 4 
LOC100293351          0.185   PREDICTED: hypothetical protein isoform 2 
LOC100293351          0.185   PREDICTED: hypothetical protein isoform 1 
LOC100293351          0.185   PREDICTED: hypothetical protein isoform 3 
KRT86                 0.185   keratin 86 
KRT81                 0.182   keratin, hair, basic, 1 
KRT83                 0.181   keratin 83 
KRT1                  0.181   keratin 1 
KRT82                 0.177   keratin 82 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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