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Search of human proteins with 54607064
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i... 1030 0.0
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i... 988 0.0
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i... 936 0.0
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ... 857 0.0
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ... 657 0.0
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ... 636 0.0
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i... 636 0.0
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ... 631 0.0
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ... 631 0.0
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i... 629 e-180
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i... 627 e-180
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ... 617 e-177
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i... 617 e-177
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ... 613 e-176
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [... 602 e-172
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i... 596 e-170
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 52 1e-06
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 50 4e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 49 9e-06
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 44 3e-04
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 44 3e-04
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 44 5e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 41 0.002
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 41 0.002
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 40 0.004
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 40 0.004
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 39 0.009
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 37 0.033
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 36 0.097
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 36 0.097
>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
Length = 520
Score = 1030 bits (2664), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1 MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
Query: 61 DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61 DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
Query: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420
LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS
Sbjct: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420
Query: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480
TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH
Sbjct: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480
Query: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
isoform c [Homo sapiens]
Length = 502
Score = 988 bits (2554), Expect = 0.0
Identities = 499/499 (100%), Positives = 499/499 (100%)
Query: 22 VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 81
VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA
Sbjct: 4 VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 63
Query: 82 AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 141
AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL
Sbjct: 64 AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 123
Query: 142 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 201
VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK
Sbjct: 124 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 183
Query: 202 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 261
QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA
Sbjct: 184 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 243
Query: 262 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 321
DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ
Sbjct: 244 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 303
Query: 322 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE 381
LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE
Sbjct: 304 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE 363
Query: 382 NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS 441
NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS
Sbjct: 364 NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS 423
Query: 442 NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 501
NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK
Sbjct: 424 NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 483
Query: 502 PHRNRGSPGGYSHDSRHRL 520
PHRNRGSPGGYSHDSRHRL
Sbjct: 484 PHRNRGSPGGYSHDSRHRL 502
>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
Length = 486
Score = 936 bits (2420), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 169
DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135
Query: 170 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 229
RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195
Query: 230 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 289
KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255
Query: 290 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 349
AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315
Query: 350 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 409
GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP
Sbjct: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375
Query: 410 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 469
MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK
Sbjct: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435
Query: 470 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486
>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
Length = 458
Score = 857 bits (2213), Expect = 0.0
Identities = 451/520 (86%), Positives = 452/520 (86%), Gaps = 62/520 (11%)
Query: 1 MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1 MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
Query: 61 DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61 DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
Query: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420
LVAADKLAQCPP R H+ ST
Sbjct: 361 LVAADKLAQCPPSQ-------------------------RMRHSNHST------------ 383
Query: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480
ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH
Sbjct: 384 -------------------------ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 418
Query: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 419 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458
>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
Length = 622
Score = 657 bits (1695), Expect = 0.0
Identities = 355/524 (67%), Positives = 409/524 (78%), Gaps = 34/524 (6%)
Query: 29 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
R++R K SDGST TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 48 RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
Query: 85 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
LE+AK+KPVAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
GCEIGFIPSP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+AKQ
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226
Query: 203 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 262
KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286
Query: 263 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 322
ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346
Query: 323 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDEN 382
KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDEN
Sbjct: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406
Query: 383 QLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ-------- 434
QLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT S Q
Sbjct: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466
Query: 435 --SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRD 483
S +R ++ + E +E + +S +HN R+ SR S +Q SRD
Sbjct: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526
Query: 484 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
Y +EDY + D Y HR+ GS +SRHR
Sbjct: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570
>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
Length = 608
Score = 636 bits (1641), Expect = 0.0
Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)
Query: 29 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
R++R K SDGST TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 20 RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78
Query: 85 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
LE+AK+KPVAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138
Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
GCEIGFIPSP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+ +
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198
Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258
Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318
Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378
Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 428
QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438
Query: 429 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 471
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498
Query: 472 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
isoform 4 [Homo sapiens]
Length = 636
Score = 636 bits (1641), Expect = 0.0
Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)
Query: 29 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
R++R K SDGST TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 48 RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
Query: 85 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
LE+AK+KPVAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
GCEIGFIPSP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+ +
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 226
Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 227 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 286
Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 287 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 346
Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 347 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 406
Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 428
QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 407 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 466
Query: 429 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 471
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 467 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 526
Query: 472 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 527 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 584
>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
isoform 6 [Homo sapiens]
Length = 632
Score = 631 bits (1628), Expect = 0.0
Identities = 353/562 (62%), Positives = 409/562 (72%), Gaps = 72/562 (12%)
Query: 29 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
R++R K SDGST TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 20 RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78
Query: 85 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
LE+AK+KPVAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138
Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
GCEIGFIPSP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 198
Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
K+K+ K TEH PPYDVVPSMRPVVL
Sbjct: 199 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 258
Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 259 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 318
Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 319 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 378
Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHT 404
LIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH
Sbjct: 379 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 438
Query: 405 TSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE--- 451
SS+ PLL R L +++L PT S Q S +R ++ + E +E
Sbjct: 439 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 498
Query: 452 -RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHR 504
+ +S +HN R+ SR S +Q SRD Y +EDY + D Y HR
Sbjct: 499 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 558
Query: 505 N-------RGSPGGYSHDSRHR 519
+ GS +SRHR
Sbjct: 559 DHNHRDETHGSSDHRHRESRHR 580
>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
isoform 2 [Homo sapiens]
Length = 660
Score = 631 bits (1628), Expect = 0.0
Identities = 353/562 (62%), Positives = 409/562 (72%), Gaps = 72/562 (12%)
Query: 29 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
R++R K SDGST TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 48 RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
Query: 85 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
LE+AK+KPVAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
GCEIGFIPSP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 226
Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
K+K+ K TEH PPYDVVPSMRPVVL
Sbjct: 227 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 286
Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 287 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 346
Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 347 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 406
Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHT 404
LIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH
Sbjct: 407 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 466
Query: 405 TSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE--- 451
SS+ PLL R L +++L PT S Q S +R ++ + E +E
Sbjct: 467 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 526
Query: 452 -RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHR 504
+ +S +HN R+ SR S +Q SRD Y +EDY + D Y HR
Sbjct: 527 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 586
Query: 505 N-------RGSPGGYSHDSRHR 519
+ GS +SRHR
Sbjct: 587 DHNHRDETHGSSDHRHRESRHR 608
>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
Length = 598
Score = 629 bits (1621), Expect = e-180
Identities = 322/463 (69%), Positives = 376/463 (81%), Gaps = 16/463 (3%)
Query: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
Query: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242
Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302
Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362
Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
QSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP P
Sbjct: 363 QSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNP 422
Query: 413 LLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSL 455
LL R + + AL+ P +S LQ + + E + E S+
Sbjct: 423 LLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASM 465
>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
isoform 3 [Homo sapiens]
Length = 478
Score = 627 bits (1617), Expect = e-180
Identities = 320/444 (72%), Positives = 370/444 (83%), Gaps = 16/444 (3%)
Query: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
Query: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242
Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302
Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362
Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
QSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP P
Sbjct: 363 QSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNP 422
Query: 413 LLGRNLGSTALSPYPTAISGLQSQ 436
LL R + + AL+ P +S LQ Q
Sbjct: 423 LLNRTMATAALAASPAPVSNLQVQ 446
>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
isoform 3 [Homo sapiens]
Length = 606
Score = 617 bits (1592), Expect = e-177
Identities = 341/544 (62%), Positives = 396/544 (72%), Gaps = 67/544 (12%)
Query: 43 TSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVS 102
T +I+ GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVS
Sbjct: 11 TKYIIPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVS 70
Query: 103 YCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRI 162
Y A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+
Sbjct: 71 YSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRL 130
Query: 163 QQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-------------------- 200
Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 131 QHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHR 190
Query: 201 --------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 242
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 191 SPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 250
Query: 243 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFEL 302
FDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 251 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 310
Query: 303 ARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLV 362
AR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+V
Sbjct: 311 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 370
Query: 363 AADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTA 422
AADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++
Sbjct: 371 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 430
Query: 423 LSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERAR 468
L PT S Q S +R ++ + E +E + +S +HN R+
Sbjct: 431 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 490
Query: 469 KSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHD 515
SR S +Q SRD Y +EDY + D Y HR+ GS +
Sbjct: 491 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 550
Query: 516 SRHR 519
SRHR
Sbjct: 551 SRHR 554
>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
isoform 7 [Homo sapiens]
Length = 612
Score = 617 bits (1591), Expect = e-177
Identities = 345/554 (62%), Positives = 399/554 (72%), Gaps = 69/554 (12%)
Query: 33 LKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKP 92
LKR+ G S I GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KP
Sbjct: 9 LKRAKGGRLKNSDIC--GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP 66
Query: 93 VAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIP 152
VAFAV+TNVSY A ++DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIP
Sbjct: 67 VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP 126
Query: 153 SPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA---------- 200
SP++LEN+R+Q EQ K+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 127 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA 186
Query: 201 ------------------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGY
Sbjct: 187 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY 246
Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
EVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEV
Sbjct: 247 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV 306
Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
QSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKS
Sbjct: 307 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS 366
Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
Q+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ P
Sbjct: 367 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP 426
Query: 413 LLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTS 458
LL R L +++L PT S Q S +R ++ + E +E + +S
Sbjct: 427 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS 486
Query: 459 DENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN------- 505
+HN R+ SR S +Q SRD Y +EDY + D Y HR+
Sbjct: 487 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET 546
Query: 506 RGSPGGYSHDSRHR 519
GS +SRHR
Sbjct: 547 HGSSDHRHRESRHR 560
>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
Length = 605
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 17 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 167
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 77 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
Query: 168 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 200
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
Query: 201 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 249
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
Query: 250 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 309
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
Query: 310 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
Query: 370 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 429
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
Query: 430 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 471
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
Query: 472 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
Length = 484
Score = 602 bits (1551), Expect = e-172
Identities = 331/474 (69%), Positives = 368/474 (77%), Gaps = 33/474 (6%)
Query: 50 GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 108
GSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 168
E+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK
Sbjct: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
Query: 169 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
R SGN SS L ++ G R+ P S AKQKQK EH+PPYDVVPSMRPVVLVGPS
Sbjct: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186
Query: 229 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 288
LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
Query: 289 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 348
+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306
Query: 349 RGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSST 408
RGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL EYLE YWRATH +
Sbjct: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366
Query: 409 PMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERAR 468
P LLG P+AI GLQ+Q++ E+SP+ER SLM SD E +
Sbjct: 367 P--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERDSLMPSD-----EASE 408
Query: 469 KSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 520
SR + SSQ S H +EEDY D+YQD Y+PHR G P HD + RL
Sbjct: 409 SSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459
>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
Length = 523
Score = 596 bits (1537), Expect = e-170
Identities = 315/489 (64%), Positives = 366/489 (74%), Gaps = 61/489 (12%)
Query: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
Query: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ---------------------------- 204
KS NSSSSLG++V+GT R TP ++ +
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTS 242
Query: 205 -----------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLK 247
K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLK
Sbjct: 243 VSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLK 302
Query: 248 HRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQ 307
HRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFELAR+LQ
Sbjct: 303 HRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 362
Query: 308 LVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKL 367
LV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KL
Sbjct: 363 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKL 422
Query: 368 AQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYP 427
AQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP PLL R + + AL+ P
Sbjct: 423 AQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASP 482
Query: 428 TAISGLQSQ 436
+S LQ Q
Sbjct: 483 APVSNLQVQ 491
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/301 (22%), Positives = 121/301 (40%), Gaps = 29/301 (9%)
Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQEQ 166
D +PS +SF D LH+ +++WW RLV E +IG IPS R+E + +
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK-KERARL 575
Query: 167 KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRPVVLV 225
K +FH S+ + + A + Q+ + + P + RPV+++
Sbjct: 576 KTVKFHARTGMIESNRDFPGLSDDYYGA--KNLKGQEDAILSYEPVTRQEIHYARPVIIL 633
Query: 226 GPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTAD---------ISLAKRSVLNNPS 275
GP + D + L H+F + TR D +++ + +
Sbjct: 634 GP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQ 687
Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
IE +L + I+ + +A + +LD N +L + L PI + +K
Sbjct: 688 DNKFIEAGQFNDNL--YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK 744
Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
PK ++ L++ + + N A KL Q E F I+ + LE+ + + +
Sbjct: 745 ---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQII 801
Query: 396 E 396
E
Sbjct: 802 E 802
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 50.4 bits (119), Expect = 4e-06
Identities = 72/330 (21%), Positives = 130/330 (39%), Gaps = 55/330 (16%)
Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLE-------- 158
D +PS +SF D LH+ +++WW RLV E +IG IPS R+E
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLK 239
Query: 159 -------------NIRIQQEQKRG-------RFHGGKSSGNSSSSLGEM-VSGTFRATPT 197
N I+ ++K+ F+ K + SS+ E V+ + +
Sbjct: 240 TVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSES 299
Query: 198 STAKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 255
S+ Q+ + + P + RPV+++GP + D + L H+F +
Sbjct: 300 SSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPH 353
Query: 256 ITRVTAD---------ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSL 306
TR D +++ + + IE +L + I+ + +A
Sbjct: 354 TTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL--YGTSIQSVRAVAERG 411
Query: 307 QLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADK 366
+ +LD N +L + L PI + +K PK ++ L++ + + N A K
Sbjct: 412 KHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMK 467
Query: 367 LAQCPPEMFDVILDENQLEDACEHLGEYLE 396
L Q E F I+ + LE+ + + +E
Sbjct: 468 LEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 49.3 bits (116), Expect = 9e-06
Identities = 63/307 (20%), Positives = 122/307 (39%), Gaps = 32/307 (10%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
+D +PS ++F D LH+ +++WW R V E E+G IPS R+E + +
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK-KERAR 654
Query: 166 QKRGRFHG-GKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSM----- 219
K +F+ + G +G + + + + E++ Y+ V
Sbjct: 655 LKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYT 714
Query: 220 RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL---------AKRS 269
RPV+++GP + D + L +F + TR D + ++
Sbjct: 715 RPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQ 768
Query: 270 VLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAP 329
+ + + IE + L + ++ + E+A + +LD N +L L P
Sbjct: 769 MEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLYP 825
Query: 330 IIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACE 389
I + +K PK ++ +++ + + A KL Q E F I+ + LED
Sbjct: 826 ISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYN 882
Query: 390 HLGEYLE 396
+ + +E
Sbjct: 883 QVKQIIE 889
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)
Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
S A+SF D LH+ + + +WW R V E +IGFIPS R+E ++E R +
Sbjct: 492 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 546
Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 231
K G+SS S G S T T V RP++++GP+ K
Sbjct: 547 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 588
Query: 232 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 275
D++ + F ++ DGR S ++ DI K
Sbjct: 589 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 640
Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
IE S L + ++ + E+A + +LD + N +L L PI + ++
Sbjct: 641 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 694
Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
P+ L+ +++ + + A KL Q E F I++ + E+ + +
Sbjct: 695 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 751
Query: 396 E 396
E
Sbjct: 752 E 752
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)
Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
S A+SF D LH+ + + +WW R V E +IGFIPS R+E ++E R +
Sbjct: 446 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 500
Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 231
K G+SS S G S T T V RP++++GP+ K
Sbjct: 501 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 542
Query: 232 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 275
D++ + F ++ DGR S ++ DI K
Sbjct: 543 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 594
Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
IE S L + ++ + E+A + +LD + N +L L PI + ++
Sbjct: 595 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 648
Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
P+ L+ +++ + + A KL Q E F I++ + E+ + +
Sbjct: 649 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 705
Query: 396 E 396
E
Sbjct: 706 E 706
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 43.5 bits (101), Expect = 5e-04
Identities = 67/328 (20%), Positives = 127/328 (38%), Gaps = 52/328 (15%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRL---ENIRI 162
+D +PS ++F D LH+ +++WW R V E E+G IPS R+ E R+
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARL 655
Query: 163 Q------QEQKRGRFHGGKSSGN-----------------SSSSLGEMVSGTFRATPTST 199
+ + + +G+ K N +S + V+ + +S
Sbjct: 656 KTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSY 715
Query: 200 AKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SIT 257
Q++ V + P V RPV+++GP + D + L +F + T
Sbjct: 716 RGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTT 769
Query: 258 RVTADISL---------AKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
R D + ++ + + + IE + L + ++ + E+A +
Sbjct: 770 RPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKH 827
Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
+LD N +L L PI + +K PK ++ +++ + + A KL
Sbjct: 828 CILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLE 883
Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLE 396
Q E F I+ + LED + + +E
Sbjct: 884 QEFTEHFTAIVQGDTLEDIYNQVKQIIE 911
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 448 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 506
Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
K +F+ G S LG+ GT + Q+ + + P + RP
Sbjct: 507 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 561
Query: 222 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 271
V+++GP + D + L +F + TR D +++ +
Sbjct: 562 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 615
Query: 272 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 331
+ + IE +L + ++ + +A + +LD N +L L PI
Sbjct: 616 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 672
Query: 332 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 386
+ +K S + L + K + Q+K + + KL Q E F I+ + LED
Sbjct: 673 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 724
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 33 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 91
Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
K +F+ G S LG+ GT + Q+ + + P + RP
Sbjct: 92 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 146
Query: 222 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 271
V+++GP + D + L +F + TR D +++ +
Sbjct: 147 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 200
Query: 272 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 331
+ + IE +L + ++ + +A + +LD N +L L PI
Sbjct: 201 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 257
Query: 332 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 386
+ +K S + L + K + Q+K + + KL Q E F I+ + LED
Sbjct: 258 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 309
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 40.4 bits (93), Expect = 0.004
Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 656 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 714
Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
K +F+ +S S + +F + T+ ++ + I Y
Sbjct: 715 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 774
Query: 214 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 264
+ V RPV+++GP + D + L +F + TR D
Sbjct: 775 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 828
Query: 265 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 318
+++ + + + IE +L + ++ + +A + +LD N
Sbjct: 829 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 885
Query: 319 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 378
+L L PI + +K S + L + K + Q+K + + KL Q E F I
Sbjct: 886 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 942
Query: 379 LDENQLED 386
+ + LED
Sbjct: 943 VQGDTLED 950
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 40.4 bits (93), Expect = 0.004
Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)
Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 551 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 609
Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
K +F+ +S S + +F + T+ ++ + I Y
Sbjct: 610 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 669
Query: 214 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 264
+ V RPV+++GP + D + L +F + TR D
Sbjct: 670 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 723
Query: 265 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 318
+++ + + + IE +L + ++ + +A + +LD N
Sbjct: 724 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 780
Query: 319 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 378
+L L PI + +K S + L + K + Q+K + + KL Q E F I
Sbjct: 781 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 837
Query: 379 LDENQLED 386
+ + LED
Sbjct: 838 VQGDTLED 845
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 39.3 bits (90), Expect = 0.009
Identities = 70/332 (21%), Positives = 129/332 (38%), Gaps = 37/332 (11%)
Query: 84 QLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK 143
Q++ +K VK + Y + D VP +SF D LH+ + + +WW + +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394
Query: 144 EGCE-----IGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTS 198
EG E G +P ++ + Q+E + K S + R
Sbjct: 395 EGDEDNQPLAGLVPG----KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
Query: 199 TA-KQKQKVTEHIPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF 250
A K E I Y+ + RP++L+GP G + +++ L + K RF
Sbjct: 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRF 507
Query: 251 DGRI-SITRVTADISLAKRSVLNNPSKRA---------IIERSNTRSSLAEVQSEIERIF 300
+ TR D +A R + S++A IE +L + I+ +
Sbjct: 508 ASAVPHTTRSRRDQEVAGRD-YHFVSRQAFEADIAAGKFIEHGEFEKNL--YGTSIDSVR 564
Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS-QSKHLNV 359
++ S ++ +L T L + L P I+ + S + L+ L+ GK+ + + L
Sbjct: 565 QVINSGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELRE 623
Query: 360 QLVAADKLAQCPPEMFDVILDENQLEDACEHL 391
+ ++ Q FD + + L+ A + L
Sbjct: 624 IIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 37.4 bits (85), Expect = 0.033
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 14/140 (10%)
Query: 92 PVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFI 151
P VK + Y D +P + F + L I + + +WW VKEG G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274
Query: 152 PSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP 211
PS E+KR F + NS G + S + T + + I
Sbjct: 275 PSQF--------LEEKRKAF-VRRDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHEIQ 325
Query: 212 PYDVVPSMRP-----VVLVG 226
Y+ V M P +VL+G
Sbjct: 326 IYEEVAKMPPFQRKTLVLIG 345
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 35.8 bits (81), Expect = 0.097
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 97 VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
V+ Y A D+ +P I F D + I K +++WW G+L + G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 35.8 bits (81), Expect = 0.097
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 97 VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
V+ Y A D+ +P I F D + I K +++WW G+L + G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,537,025
Number of Sequences: 37866
Number of extensions: 855867
Number of successful extensions: 3376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 3274
Number of HSP's gapped (non-prelim): 116
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.