Search of human proteins with 53988380

Search of human proteins with 53988380

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]
         (630 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]        1258   0.0  
gi|53988378 mesothelin isoform 1 preproprotein [Homo sapiens]        1233   0.0  
gi|68448528 mesothelin-like [Homo sapiens]                            158   1e-38
gi|194440719 chondroadherin-like [Homo sapiens]                        42   0.002
gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i...    32   1.4  
gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i...    32   1.4  
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...    31   3.9  
gi|239757315 PREDICTED: hypothetical protein [Homo sapiens]            31   3.9  
gi|239751820 PREDICTED: hypothetical protein [Homo sapiens]            31   3.9  
gi|239746311 PREDICTED: hypothetical protein XP_002343692 [Homo ...    31   3.9  
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]          31   3.9  
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]           31   3.9  
gi|41350201 epsin 1 isoform c [Homo sapiens]                           30   5.2  
gi|194248095 epsin 1 isoform b [Homo sapiens]                          30   5.2  
gi|194272148 epsin 1 isoform a [Homo sapiens]                          30   5.2  
gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ...    30   5.2  
gi|23943862 N-acetyltransferase 14 [Homo sapiens]                      30   6.7  
gi|5730021 regulatory solute carrier protein, family 1, member 1...    30   6.7  
gi|13491166 pumilio 1 isoform 2 [Homo sapiens]                         30   8.8  
gi|66932909 pumilio 1 isoform 1 [Homo sapiens]                         30   8.8  
gi|169209574 PREDICTED: hypothetical protein LOC400558 [Homo sap...    30   8.8  
gi|169210581 PREDICTED: hypothetical protein LOC400558 [Homo sap...    30   8.8  
gi|169210101 PREDICTED: hypothetical protein LOC400558 [Homo sap...    30   8.8  
gi|164519122 LGN protein [Homo sapiens]                                30   8.8  

>gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]
          Length = 630

 Score = 1258 bits (3254), Expect = 0.0
 Identities = 630/630 (100%), Positives = 630/630 (100%)

Query: 1   MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 60
           MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS
Sbjct: 1   MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 60

Query: 61  LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 120
           LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL
Sbjct: 61  LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 120

Query: 121 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 180
           DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA
Sbjct: 121 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 180

Query: 181 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 240
           DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW
Sbjct: 181 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 240

Query: 241 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 300
           SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT
Sbjct: 241 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 300

Query: 301 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 360
           ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY
Sbjct: 301 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 360

Query: 361 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVA 420
           PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVA
Sbjct: 361 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVA 420

Query: 421 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ 480
           TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ
Sbjct: 421 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ 480

Query: 481 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL 540
           LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL
Sbjct: 481 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL 540

Query: 541 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS 600
           PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS
Sbjct: 541 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS 600

Query: 601 MQEALSGTPCLLGPGPVLTVLALLLASTLA 630
           MQEALSGTPCLLGPGPVLTVLALLLASTLA
Sbjct: 601 MQEALSGTPCLLGPGPVLTVLALLLASTLA 630


>gi|53988378 mesothelin isoform 1 preproprotein [Homo sapiens]
          Length = 622

 Score = 1233 bits (3191), Expect = 0.0
 Identities = 622/630 (98%), Positives = 622/630 (98%), Gaps = 8/630 (1%)

Query: 1   MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 60
           MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS
Sbjct: 1   MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 60

Query: 61  LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 120
           LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL
Sbjct: 61  LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 120

Query: 121 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 180
           DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA
Sbjct: 121 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 180

Query: 181 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 240
           DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW
Sbjct: 181 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 240

Query: 241 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 300
           SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT
Sbjct: 241 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 300

Query: 301 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 360
           ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY
Sbjct: 301 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 360

Query: 361 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVA 420
           PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMS        PQVA
Sbjct: 361 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMS--------PQVA 412

Query: 421 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ 480
           TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ
Sbjct: 413 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ 472

Query: 481 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL 540
           LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL
Sbjct: 473 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL 532

Query: 541 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS 600
           PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS
Sbjct: 533 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS 592

Query: 601 MQEALSGTPCLLGPGPVLTVLALLLASTLA 630
           MQEALSGTPCLLGPGPVLTVLALLLASTLA
Sbjct: 593 MQEALSGTPCLLGPGPVLTVLALLLASTLA 622


>gi|68448528 mesothelin-like [Homo sapiens]
          Length = 1053

 Score =  158 bits (400), Expect = 1e-38
 Identities = 151/552 (27%), Positives = 233/552 (42%), Gaps = 77/552 (13%)

Query: 100 QLRCLAHRLSEP--PEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAP 157
           QL CLA+  S     +D    P +LLLF N         C  F  R  + +V+LL     
Sbjct: 419 QLSCLANLASRCGLQDDFTLHPPNLLLFYNLSQVREAD-CRAFIRRAAQGDVELLSHLPD 477

Query: 158 ERQRLLPAALAC-----WG----VRGSL----------------LSEADVRALGGLACDL 192
           +R  L  AA+AC     WG    + GSL                LS +D + LG L CD+
Sbjct: 478 QRVALWRAAVACLVGAGWGWARCIGGSLPLGADLLALQGVARLRLSASDQQLLGALVCDM 537

Query: 193 PGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLL 252
               +  +   +L  L  CP  L   Q+ A  + L GG    GPP +W++  + AL  L 
Sbjct: 538 DASSIGAADPHMLENLRRCPR-LTAAQRIALNSLLAGGKTSLGPPGSWTLEGLQALGPLA 596

Query: 253 PVLGQPIIRSIPQGI-------------VAAWRQRSSRD--PSWRQPERTILRPRFRREV 297
             +   +   + + +             V    QR +R    S+ + +    +P   R  
Sbjct: 597 TYISPHLWAQVQEAVGLGFFRSVVASCQVGRLGQREARCFVTSFLESKT---KPVSSRPR 653

Query: 298 EKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLD 357
             T   +    R+ D  L+ Y   ELE+C+D  +L T +D +       E   V+K KL 
Sbjct: 654 LSTGNITAATLRD-DLFLVHYDCAELESCLDGCILRTNLDTLLQHLLPTECQHVVKAKLA 712

Query: 358 ELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLP 417
           ++YPQG PE  ++ +  L    S  +I +W++TS +T+ ALL  +   E   +A      
Sbjct: 713 QIYPQGLPEDQLRLITSLVYLYSRTEIGQWSITSQDTVMALLASDVALENQTEA------ 766

Query: 418 QVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCD 477
               ++ +F++  G +       L A     LC +SP ++ ++ P  +      DL +C 
Sbjct: 767 ----VLQKFLEHNGTVSG---ALLLAIGGTRLCWMSPHQIQTIHPQELRLAGALDLSSCP 819

Query: 478 PRQLDVLYPKARLAFQNMNG-SEYFVKIQSFL---------------GGAPTEDLKALSQ 521
             + DVLY KA   F +    + Y+  ++ +L               GGAP E+L+ L+ 
Sbjct: 820 QSRKDVLYTKAHETFGSSGTLAAYYRLMRPYLGGSPGGAQPPSPVPPGGAPVEELRHLAH 879

Query: 522 QNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDT 581
            N+SMD+ TF  L    +  L V  V  LLG +V  L+    H  VR W+       L  
Sbjct: 880 ANISMDIDTFTSLNPLELQSLDVGNVTALLGHNVGDLQKARSHPTVRAWLRSLNSSTLGQ 939

Query: 582 LGLGLQGGIPNG 593
           LGL      P G
Sbjct: 940 LGLDASPTSPTG 951


>gi|194440719 chondroadherin-like [Homo sapiens]
          Length = 762

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/196 (29%), Positives = 81/196 (41%), Gaps = 21/196 (10%)

Query: 58  ISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDA 117
           +S L+P  L G P      L    ++ L   +  +   L+  +L    H       + D 
Sbjct: 194 LSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLEL---GHNPLTYAGEEDG 250

Query: 118 LPLDLL--LFLNPDAFS--GPQA---CTRFFSRITKAN-VDLLPR----GAPERQRLLPA 165
           L L  L  L L+  A    GP+A   C R  +   + N +D LP     G   R RL   
Sbjct: 251 LALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGN 310

Query: 166 ALACWGVRGSLL---SEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEA 222
            L C      LL   + A VR+ G  AC  P R   E+ + L P  + CPG   Q+++E 
Sbjct: 311 PLWCGCQARPLLEWLARARVRSDG--ACQGPRRLRGEALDALRPWDLRCPGDAAQEEEEL 368

Query: 223 ARAALQG-GGPPYGPP 237
              A+ G   PP GPP
Sbjct: 369 EERAVAGPRAPPRGPP 384


>gi|222537739 ER degradation enhancer, mannosidase alpha-like 2
           isoform 2 [Homo sapiens]
          Length = 541

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 179 EADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPS 238
           E ++R +GGL   L    +++ A V +     C GPL +  +EAAR  L    P +  P+
Sbjct: 80  ETNIRVVGGL---LSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLL----PAFQTPT 132

Query: 239 TWSVSTMDALRGLLP 253
                T++ L G+ P
Sbjct: 133 GMPYGTVNLLHGVNP 147


>gi|222537737 ER degradation enhancer, mannosidase alpha-like 2
           isoform 1 [Homo sapiens]
          Length = 578

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 179 EADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPS 238
           E ++R +GGL   L    +++ A V +     C GPL +  +EAAR  L    P +  P+
Sbjct: 117 ETNIRVVGGL---LSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLL----PAFQTPT 169

Query: 239 TWSVSTMDALRGLLP 253
                T++ L G+ P
Sbjct: 170 GMPYGTVNLLHGVNP 184


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
            sapiens]
          Length = 1560

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 202  EVLLPRLVSCPGPLDQDQQEAARAALQGGG--PPYGPPSTWSVSTMDALRGLLPVLG 256
            E L P+ V   GP  ++ QE      + GG  PP   P+T S ST +   GL P  G
Sbjct: 1475 EELEPKRVRSSGPEAEEVQEEEELEEETGGEGPPAPIPTTGSPSTQENQNGLEPAEG 1531


>gi|239757315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 144

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 4/52 (7%)

Query: 232 PPYGPPSTWSVSTMDALRGLLPVLGQPI-IRSIPQGIVAAWRQRSSRDPSWR 282
           PP GPP+   V+   A     P  G+P+  RS P   V+  + RSS D S+R
Sbjct: 12  PPLGPPARLPVT---AAAAPAPTRGRPLPYRSCPTNWVSPLQYRSSEDVSYR 60


>gi|239751820 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 144

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 4/52 (7%)

Query: 232 PPYGPPSTWSVSTMDALRGLLPVLGQPI-IRSIPQGIVAAWRQRSSRDPSWR 282
           PP GPP+   V+   A     P  G+P+  RS P   V+  + RSS D S+R
Sbjct: 12  PPLGPPARLPVT---AAAAPAPTRGRPLPYRSCPTNWVSPLQYRSSEDVSYR 60


>gi|239746311 PREDICTED: hypothetical protein XP_002343692 [Homo
           sapiens]
          Length = 144

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 4/52 (7%)

Query: 232 PPYGPPSTWSVSTMDALRGLLPVLGQPI-IRSIPQGIVAAWRQRSSRDPSWR 282
           PP GPP+   V+   A     P  G+P+  RS P   V+  + RSS D S+R
Sbjct: 12  PPLGPPARLPVT---AAAAPAPTRGRPLPYRSCPTNWVSPLQYRSSEDVSYR 60


>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 399 LEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELS 458
           L+  +G  +  Q P RPLP  A ++   V G G L   TL  L          L  E L+
Sbjct: 46  LKEGQGTSVVAQGPSRPLPSTANVV---VIGGGSLGCQTLYHLAKLGMSGAVLLERERLT 102

Query: 459 S----VPPSSIWAVRPQDLD 474
           S         +W +RP D++
Sbjct: 103 SGTTWHTAGLLWQLRPSDVE 122


>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 399 LEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELS 458
           L+  +G  +  Q P RPLP  A ++   V G G L   TL  L          L  E L+
Sbjct: 46  LKEGQGTSVVAQGPSRPLPSTANVV---VIGGGSLGCQTLYHLAKLGMSGAVLLERERLT 102

Query: 459 S----VPPSSIWAVRPQDLD 474
           S         +W +RP D++
Sbjct: 103 SGTTWHTAGLLWQLRPSDVE 122


>gi|41350201 epsin 1 isoform c [Homo sapiens]
          Length = 550

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 20/134 (14%)

Query: 149 VDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGR------FVAESAE 202
           ++LL    P R    P A    GVRGSL                P        F+  +A 
Sbjct: 398 LELLAGEVPARS---PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 454

Query: 203 VL-LPRLVSCPGPLDQDQQEAARAALQGGGPPYGP-------PSTWSVSTMDALR--GLL 252
           ++ L  LVS PGP     + A+   L GGGP  GP       P+  +  T++ LR   + 
Sbjct: 455 LVDLDSLVSRPGPTPPGAK-ASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 513

Query: 253 PVLGQPIIRSIPQG 266
           PV G P     P G
Sbjct: 514 PVPGAPPTYISPLG 527


>gi|194248095 epsin 1 isoform b [Homo sapiens]
          Length = 576

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 20/134 (14%)

Query: 149 VDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGR------FVAESAE 202
           ++LL    P R    P A    GVRGSL                P        F+  +A 
Sbjct: 424 LELLAGEVPARS---PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480

Query: 203 VL-LPRLVSCPGPLDQDQQEAARAALQGGGPPYGP-------PSTWSVSTMDALR--GLL 252
           ++ L  LVS PGP     + A+   L GGGP  GP       P+  +  T++ LR   + 
Sbjct: 481 LVDLDSLVSRPGPTPPGAK-ASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 539

Query: 253 PVLGQPIIRSIPQG 266
           PV G P     P G
Sbjct: 540 PVPGAPPTYISPLG 553


>gi|194272148 epsin 1 isoform a [Homo sapiens]
          Length = 662

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 20/134 (14%)

Query: 149 VDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGR------FVAESAE 202
           ++LL    P R    P A    GVRGSL                P        F+  +A 
Sbjct: 510 LELLAGEVPARS---PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 566

Query: 203 VL-LPRLVSCPGPLDQDQQEAARAALQGGGPPYGP-------PSTWSVSTMDALR--GLL 252
           ++ L  LVS PGP     + A+   L GGGP  GP       P+  +  T++ LR   + 
Sbjct: 567 LVDLDSLVSRPGPTPPGAK-ASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 625

Query: 253 PVLGQPIIRSIPQG 266
           PV G P     P G
Sbjct: 626 PVPGAPPTYISPLG 639


>gi|41281805 regulator of G-protein signaling 20 isoform a [Homo
           sapiens]
          Length = 388

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 40/143 (27%), Positives = 57/143 (39%), Gaps = 21/143 (14%)

Query: 106 HRLSEPPEDLDALPLDLLLFLN---PDAFSGPQ----------ACTRFFSRITKANVDLL 152
           H+++E   DL A+P D+  F     PD+ + P+          +  RFFS + +      
Sbjct: 39  HQITENEGDLRAVP-DIKSFPPAQLPDSPAAPKLFGLLSSPLSSLARFFSHLLRRPPPEA 97

Query: 153 PRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCP 212
           PR   +   LLPA  A    RG       +  L G A  LPGR        L P     P
Sbjct: 98  PRRRLDFSPLLPALPAARLSRGHEELPGRLSLLLGAALALPGR--PSGGRPLRP-----P 150

Query: 213 GPLDQDQQEAARAALQGGGPPYG 235
            P+ + ++E A A      P  G
Sbjct: 151 HPVAKPREEDATAGQSSPMPQMG 173


>gi|23943862 N-acetyltransferase 14 [Homo sapiens]
          Length = 206

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 155 GAPERQRLLPAALACWGVRGSLLSEADVRALGGLAC 190
           G P  + ++P A+A WGV G +L     +A GG  C
Sbjct: 159 GEPRARLVVPVAVAAWGV-GGMLEGCGYQAEGGWGC 193


>gi|5730021 regulatory solute carrier protein, family 1, member 1
           [Homo sapiens]
          Length = 617

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 8/92 (8%)

Query: 453 SPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQ------S 506
           +P  L+    +S+  ++P D D  +P+ +  L  KA   FQ  +  +  + +Q      S
Sbjct: 25  NPMSLARSVSASVCPIKPSDSDRIEPKAVKAL--KASAEFQLNSEKKEHLSLQDLSDHAS 82

Query: 507 FLGGAPTEDLKALSQQNVSMDLATFMKLRTDA 538
               APT+   A+  QN S ++     L   A
Sbjct: 83  SADHAPTDQSPAMPMQNSSEEITVAGNLEKSA 114


>gi|13491166 pumilio 1 isoform 2 [Homo sapiens]
          Length = 1186

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 13/34 (38%), Positives = 18/34 (52%)

Query: 494 NMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMD 527
           N NGSE   ++ S  G  P ED   +  Q+V +D
Sbjct: 315 NQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLD 348


>gi|66932909 pumilio 1 isoform 1 [Homo sapiens]
          Length = 1188

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 13/34 (38%), Positives = 18/34 (52%)

Query: 494 NMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMD 527
           N NGSE   ++ S  G  P ED   +  Q+V +D
Sbjct: 315 NQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLD 348


>gi|169209574 PREDICTED: hypothetical protein LOC400558 [Homo
           sapiens]
          Length = 241

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 213 GPLDQDQQEAARAALQGGG----PPY---GPPSTWSVSTMDALRGLLPVLGQP 258
           GP  Q Q  A R  L+G G     P+    PP T SV T   L GL+  L  P
Sbjct: 38  GPTTQSQPHALRPGLRGRGGWWPQPFWIHSPPLTHSVGTFICLDGLVCALKAP 90


>gi|169210581 PREDICTED: hypothetical protein LOC400558 [Homo
           sapiens]
          Length = 241

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 213 GPLDQDQQEAARAALQGGG----PPY---GPPSTWSVSTMDALRGLLPVLGQP 258
           GP  Q Q  A R  L+G G     P+    PP T SV T   L GL+  L  P
Sbjct: 38  GPTTQSQPHALRPGLRGRGGWWPQPFWIHSPPLTHSVGTFICLDGLVCALTAP 90


>gi|169210101 PREDICTED: hypothetical protein LOC400558 [Homo
           sapiens]
          Length = 241

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 213 GPLDQDQQEAARAALQGGG----PPY---GPPSTWSVSTMDALRGLLPVLGQP 258
           GP  Q Q  A R  L+G G     P+    PP T SV T   L GL+  L  P
Sbjct: 38  GPTTQSQPHALRPGLRGRGGWWPQPFWIHSPPLTHSVGTFICLDGLVCALTAP 90


>gi|164519122 LGN protein [Homo sapiens]
          Length = 684

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 45/181 (24%), Positives = 66/181 (36%), Gaps = 44/181 (24%)

Query: 377 LKMSPEDIRKWNVTSLETLK--------ALLEVN--KGHEMSPQAPRRPLPQVATLID-R 425
           +K++PE ++ WN   L   K         LL VN  KG +    +  + L   +  ID R
Sbjct: 415 MKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDASNSIDHR 474

Query: 426 FVKGRGQLDKDTL------DTLTAFYPGYL-----------CSLSPEELSSVPP------ 462
               + ++  DT+      D L+ F    +           C  +    SS PP      
Sbjct: 475 IPNSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHTASTTTSSTPPKMMLKT 534

Query: 463 SSIWAVRPQD------LDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDL 516
           SS+  V P        L +   R+LD      R +F N+ G       QS L    T D 
Sbjct: 535 SSVPVVSPNTDEFLDLLASSQSRRLD----DQRASFSNLPGLRLTQNSQSVLSHLMTNDN 590

Query: 517 K 517
           K
Sbjct: 591 K 591


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,942,712
Number of Sequences: 37866
Number of extensions: 1347370
Number of successful extensions: 3569
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3554
Number of HSP's gapped (non-prelim): 25
length of query: 630
length of database: 18,247,518
effective HSP length: 108
effective length of query: 522
effective length of database: 14,157,990
effective search space: 7390470780
effective search space used: 7390470780
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.