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Search of human proteins with 51093832
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
sapiens]
(1487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s... 2942 0.0
gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo ... 86 3e-16
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 58 8e-08
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 51 7e-06
gi|116089337 IQ motif containing GTPase activating protein 2 [Ho... 50 2e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 49 4e-05
gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 47 1e-04
gi|4557793 neurofibromin isoform 2 [Homo sapiens] 47 1e-04
gi|217330641 IWS1 homolog [Homo sapiens] 47 2e-04
gi|18466802 Ras and Rab interactor 2 [Homo sapiens] 46 2e-04
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] 46 3e-04
gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens] 46 3e-04
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens] 44 0.001
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 41 0.008
gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.010
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 40 0.022
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho... 40 0.022
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 39 0.037
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.037
gi|68989256 ras inhibitor RIN1 [Homo sapiens] 39 0.037
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 39 0.037
gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens] 39 0.049
gi|109826564 neurofibromin isoform 1 [Homo sapiens] 38 0.083
gi|5729812 elongation factor RNA polymerase II [Homo sapiens] 38 0.083
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi... 38 0.083
gi|8923771 ELG protein isoform b [Homo sapiens] 37 0.11
gi|166295179 ELG protein isoform a [Homo sapiens] 37 0.11
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 37 0.11
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 37 0.11
gi|112421108 capicua homolog [Homo sapiens] 37 0.14
>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
sapiens]
Length = 1487
Score = 2942 bits (7627), Expect = 0.0
Identities = 1487/1487 (100%), Positives = 1487/1487 (100%)
Query: 1 MVKLDIHTLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLII 60
MVKLDIHTLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLII
Sbjct: 1 MVKLDIHTLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLII 60
Query: 61 TSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSLVAGEKL 120
TSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSLVAGEKL
Sbjct: 61 TSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSLVAGEKL 120
Query: 121 NQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSI 180
NQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSI
Sbjct: 121 NQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSI 180
Query: 181 LFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGS 240
LFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGS
Sbjct: 181 LFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGS 240
Query: 241 DRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVG 300
DRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVG
Sbjct: 241 DRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVG 300
Query: 301 EVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGD 360
EVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGD
Sbjct: 301 EVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGD 360
Query: 361 PRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYITYSQLITLVNF 420
PRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYITYSQLITLVNF
Sbjct: 361 PRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYITYSQLITLVNF 420
Query: 421 MKSVMSGDQLREDRMALDNLLANLPPAKPGKSSSLEMTPYNTPQLSPATTPANKKNRLPI 480
MKSVMSGDQLREDRMALDNLLANLPPAKPGKSSSLEMTPYNTPQLSPATTPANKKNRLPI
Sbjct: 421 MKSVMSGDQLREDRMALDNLLANLPPAKPGKSSSLEMTPYNTPQLSPATTPANKKNRLPI 480
Query: 481 ATRSRSRTNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNMQL 540
ATRSRSRTNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNMQL
Sbjct: 481 ATRSRSRTNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNMQL 540
Query: 541 SDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVSELG 600
SDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVSELG
Sbjct: 541 SDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVSELG 600
Query: 601 AGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVL 660
AGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVL
Sbjct: 601 AGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVL 660
Query: 661 GSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWSVEVL 720
GSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWSVEVL
Sbjct: 661 GSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWSVEVL 720
Query: 721 PSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIPN 780
PSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIPN
Sbjct: 721 PSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIPN 780
Query: 781 KIEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQLSSSAHQ 840
KIEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQLSSSAHQ
Sbjct: 781 KIEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQLSSSAHQ 840
Query: 841 LTSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPN 900
LTSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPN
Sbjct: 841 LTSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPN 900
Query: 901 FGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAA 960
FGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAA
Sbjct: 901 FGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAA 960
Query: 961 AIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPF 1020
AIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPF
Sbjct: 961 AIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPF 1020
Query: 1021 RKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANY 1080
RKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANY
Sbjct: 1021 RKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANY 1080
Query: 1081 ESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKKLRLALCSA 1140
ESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKKLRLALCSA
Sbjct: 1081 ESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKKLRLALCSA 1140
Query: 1141 DSVAFPVLTHSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMRCVCRF 1200
DSVAFPVLTHSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMRCVCRF
Sbjct: 1141 DSVAFPVLTHSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMRCVCRF 1200
Query: 1201 DNRTCRKLLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTT 1260
DNRTCRKLLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTT
Sbjct: 1201 DNRTCRKLLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTT 1260
Query: 1261 VCVRLLLESKEKKIREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQ 1320
VCVRLLLESKEKKIREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQ
Sbjct: 1261 VCVRLLLESKEKKIREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQ 1320
Query: 1321 DAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLRE 1380
DAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLRE
Sbjct: 1321 DAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLRE 1380
Query: 1381 APWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLI 1440
APWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLI
Sbjct: 1381 APWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLI 1440
Query: 1441 KANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTIDDRK 1487
KANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTIDDRK
Sbjct: 1441 KANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTIDDRK 1487
>gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo
sapiens]
Length = 491
Score = 85.5 bits (210), Expect = 3e-16
Identities = 49/176 (27%), Positives = 92/176 (52%), Gaps = 15/176 (8%)
Query: 1317 EQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKV------VTANHRA 1370
E+++ IE+ +M R++K F P D +D + + I+ L V V N
Sbjct: 202 ERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDI 261
Query: 1371 LQIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADD 1430
++ ++ ++ A ++I + + + PRDK+ CI + I N + + + ADD
Sbjct: 262 PEVSDMVVK------AITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPA-SADD 314
Query: 1431 FVPVLVFVLIKANPPCLLSTVQYISSFY--ASCLSGEESYWWMQFTAAVEFIKTID 1484
F+P L+++++K NPP L S +QYI+ F + ++GE+ Y++ AV FI+ +D
Sbjct: 315 FLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLD 370
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 57.8 bits (138), Expect = 8e-08
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 1342 NQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLREAPWPSAQSEIRTISAYKTPRD 1401
++DG + Q+ + L+ T +PEV + E S + S P
Sbjct: 704 SKDGSL--QQLKENQLVILATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYS----PEK 757
Query: 1402 KVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSFYASC 1461
K+ +L+ C I + ++L N GADDF+PVL++VL ++N +L V+Y+
Sbjct: 758 KISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPA 817
Query: 1462 LS-GEESYWWMQFTAAVEFIKTID 1484
L GE SY+ A+E IK+ D
Sbjct: 818 LQLGEGSYYLTTTYGALEHIKSYD 841
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 51.2 bits (121), Expect = 7e-06
Identities = 87/424 (20%), Positives = 174/424 (41%), Gaps = 49/424 (11%)
Query: 20 VNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLIITSAEASPAECCQHAKILED 79
+ S +QL Q LN +K + + RI L ++ + + ++ + L D
Sbjct: 885 IRSNQQLEQDLNIMDIKIG--------LLVKNRITLQEVVSHCKKLTK----RNKEQLSD 932
Query: 80 TQFVD---GYKQLGFQET----AYGEFLSRLRENPRLIASSLVAGEKLNQENTQSVIYTV 132
+D G K L ++ AY L+ P +A + ++ Q T + V
Sbjct: 933 MMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAKLIF---QMPQNKTTKFMEAV 989
Query: 133 FTSLYGNCIMQEDESYLLQVLRYLIEFELKES-DNPRRLLRRGTCAFSILFKLFSEGLFS 191
SLY + + LLQ+ + ++ E+K + P+ ++ ++ + + G
Sbjct: 990 IFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNG--R 1047
Query: 192 AKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRF-------- 243
+ L L + I +L + + TDP L + + +Q E G++ +
Sbjct: 1048 GQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWI-NQTEAQTGQRSHLPYDVTPEQAL 1106
Query: 244 -RQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLS--CVDRLEVG 300
+VQ ++ L+A+ +KF+ + + P+ +R++ + TL+ D +
Sbjct: 1107 SHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATD-S 1165
Query: 301 EVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVA---RFNLMQVGRLLQQLAMTGSE 357
EV + +LL F+ PAVV P+ + I++ A +A R L V +LLQ A +
Sbjct: 1166 EVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAF 1225
Query: 358 EGDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETP------PLSSVNLLEGLSRTVVYITY 411
G + L + + F + RA + P + + + +++ +VYIT
Sbjct: 1226 SGQSQHLRVLNDYLEETHLKFRKFI--HRACQVPEPEERFAVDEYSDMVAVAKPMVYITV 1283
Query: 412 SQLI 415
+L+
Sbjct: 1284 GELV 1287
>gi|116089337 IQ motif containing GTPase activating protein 2 [Homo
sapiens]
Length = 1575
Score = 50.1 bits (118), Expect = 2e-05
Identities = 70/340 (20%), Positives = 142/340 (41%), Gaps = 26/340 (7%)
Query: 96 YGEFLSRLRENPRLIASSLVAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRY 155
Y + L+ NP +A + ++ Q + + TV +LY Q +E LL++ +
Sbjct: 885 YQQLFYLLQTNPLYLAKLIF---QMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKT 941
Query: 156 LIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDED-H 214
+E E+K + + + G + F+ G L P+++ +++D+
Sbjct: 942 ALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTL--RQLLAPVVKEIIDDKSLI 999
Query: 215 LETDPNKLIERFSPSQQEKLFGEKGSDRF---------RQKVQEMVESNEAKLVALVNKF 265
+ T+P ++ + + +Q E GE + +V+ +E++ L + +K
Sbjct: 1000 INTNPVEVYKAW-VNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKV 1058
Query: 266 IGYLKQNTYCFPHSLRWIVSQMYKTL--SCVDRLEVGEVRAMCTDLLLACFICPAVVNPE 323
+ + + P+ LR+I + ++ D E E+ + +LL ++ PA+V P+
Sbjct: 1059 LNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATE-DELLKIVGNLLYYRYMNPAIVAPD 1117
Query: 324 QYGII---SDAPINEVARFNLMQVGRLLQQLAMTGSEEGDPRTKSSLGKFDKSCVAAFLD 380
+ II + IN R NL V ++LQ A EG+ SS+ + F
Sbjct: 1118 GFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRK 1177
Query: 381 VVIGGRAVETPP----LSSVNLLEGLSRTVVYITYSQLIT 416
V P + L +S+ V+YI+ ++I+
Sbjct: 1178 YFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIIS 1217
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 48.9 bits (115), Expect = 4e-05
Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Query: 1384 PSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKAN 1443
P A+ E+ ++ +P+ K+ C+ ++ I S ADD + VL+++L+K
Sbjct: 265 PRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLLYLLVKTE 324
Query: 1444 PPCLLSTVQYISSFYASCLSGEE-SYWWMQFTAAVEFIK 1481
P ++ + YI +F S L+ +E Y F AA+E+I+
Sbjct: 325 IPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYIR 363
>gi|4506787 IQ motif containing GTPase activating protein 1 [Homo
sapiens]
Length = 1657
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/342 (19%), Positives = 145/342 (42%), Gaps = 30/342 (8%)
Query: 95 AYGEFLSRLRENPRLIASSLVAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLR 154
AY L+ NP +A + ++ Q + + +V +LY Q +E LL++ +
Sbjct: 971 AYQHLFYLLQTNPTYLAKLIF---QMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFK 1027
Query: 155 YLIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDED- 213
++ E+K + + + G + F+ G + P+++ +++D+
Sbjct: 1028 TALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNAL--RQILAPVVKEIMDDKSL 1085
Query: 214 HLETDPNKLIERFSPSQQEKLFGEKGSDRF---------RQKVQEMVESNEAKLVALVNK 264
+++TDP + + + +Q E GE + ++V+ ++S+ + A+ +K
Sbjct: 1086 NIKTDPVDIYKSW-VNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDK 1144
Query: 265 FIGYLKQNTYCFPHSLRWIVSQMYKTL--SCVDRLEVGEVRAMCTDLLLACFICPAVVNP 322
F+ + + P+ +R+I + +L D E E+ + +LL ++ PA+V P
Sbjct: 1145 FLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGE-DELLKIIGNLLYYRYMNPAIVAP 1203
Query: 323 EQYGII---SDAPINEVARFNLMQVGRLLQQLAMTGSEEGDPRTKSSLGKFDKSCVAAFL 379
+ + II + + R NL + ++LQ A GD S + ++ F
Sbjct: 1204 DAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFR 1263
Query: 380 DVVIGGRAVETPPL------SSVNLLEGLSRTVVYITYSQLI 415
A + P L + L L++ V+YI+ ++I
Sbjct: 1264 RFF--QTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEII 1303
>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
Length = 2818
Score = 47.0 bits (110), Expect = 1e-04
Identities = 61/260 (23%), Positives = 108/260 (41%), Gaps = 51/260 (19%)
Query: 149 LLQVLRYLIEFELKESDNPRRLLRRGTCAFSIL---FKLFSEGLFSAKLFLTATLHEPIM 205
L Q+L + E++ +D+ + L R + A I+ FK++ L +P++
Sbjct: 1253 LYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLL-------DPLL 1305
Query: 206 QLLVEDED----HLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVAL 261
++++ D E DP +L PS E +E N+ L+ +
Sbjct: 1306 RIVITSSDWQHVSFEVDPTRL----EPS-------------------ESLEENQRNLLQM 1342
Query: 262 VNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVN 321
KF + ++ FP LR + +Y+ +S R + A+ + + L FI PA+V+
Sbjct: 1343 TEKFFHAIISSSSEFPPQLRSVCHCLYQVVS--QRFPQNSIGAVGSAMFLR-FINPAIVS 1399
Query: 322 PEQYGIISDAPINEVARFNLMQVGRLLQQLA----MTGSEEGDPRTKSSLGKFDKSCVAA 377
P + GI+ P + R L + ++LQ +A T E P FD +
Sbjct: 1400 PYEAGILDKKPPPRIER-GLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFD-AARRF 1457
Query: 378 FLDVVIGGRAVETPPLSSVN 397
FLD+ A + P +VN
Sbjct: 1458 FLDI-----ASDCPTSDAVN 1472
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 46.6 bits (109), Expect = 2e-04
Identities = 72/332 (21%), Positives = 124/332 (37%), Gaps = 51/332 (15%)
Query: 722 SDSEAPDL--KQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIP 779
SDSE+ +L +++ + E S S++ DV + S + + G + +E++
Sbjct: 80 SDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELL 139
Query: 780 N------KIEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQ 833
N + ED+ +SD ++ SP D T D L K E+E R Q
Sbjct: 140 NGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDAL-----KPQISDSESEEPPRHQ 194
Query: 834 LSSSAHQLTSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGG 893
S S ++ P S+S + + +P+V + PP A
Sbjct: 195 ASDSENEEPPKPRMSDS------------ESEELPKPQVSDSESEEPPRHQ-----ASDS 237
Query: 894 NEARLPNFGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEE 953
LP + + S E L + R SD S DP N+ +E
Sbjct: 238 ENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESE------DPPRNQASDSEN 291
Query: 954 RELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRP---------- 1003
ELP + S +S S ++D+SR + + D D ++ ++
Sbjct: 292 EELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHS 351
Query: 1004 ---WWRKRFVSAMPKAPIPFRKKEKQEKDKDD 1032
RK+F S+ + KK+K + D+D+
Sbjct: 352 DSHMDRKKFHSS--DSEEEEHKKQKMDSDEDE 381
>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
Length = 895
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 1392 TISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTV 1451
T+ +P KV +LR+C I ++ N + GADDF+PVL +V+ + + L + +
Sbjct: 660 TMQKMYSPEKKVMLLLRVCKLIYTVME-NNSGRMYGADDFLPVLTYVIAQCDMLELDTEI 718
Query: 1452 QYISSFY-ASCLSGEESYWWMQFTAAVEFIKTIDDRK 1487
+Y+ S L GE Y+ A+ IK + +
Sbjct: 719 EYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQ 755
>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
Length = 1047
Score = 45.8 bits (107), Expect = 3e-04
Identities = 58/249 (23%), Positives = 105/249 (42%), Gaps = 36/249 (14%)
Query: 146 ESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIM 205
ES LL L + E+ D L R T A +++ + +A F+ L + I+
Sbjct: 766 ESLLLCTLN---DREISMEDEATTLFRATTLASTLMEQYMKA---TATQFVHHALKDSIL 819
Query: 206 QLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKF 265
+++ E + E P+KL EK D V +N L+ ++++
Sbjct: 820 KIM-ESKQSCELSPSKL--------------EKNED---------VNTNLTHLLNILSEL 855
Query: 266 IGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQY 325
+ + + P +LR+I + K++ + + + ICPA++NP +
Sbjct: 856 VEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMF 915
Query: 326 GIISDAPINEVARFNLMQVGRLLQQLAMT---GSEEGDPRTKSSLGKFDKSCVAAFLDVV 382
IISD+P + +A L+ V + +Q LA G++E + K +K + FLD +
Sbjct: 916 NIISDSP-SPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDEL 974
Query: 383 IGGRAVETP 391
G E P
Sbjct: 975 --GNVPELP 981
>gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]
Length = 870
Score = 45.8 bits (107), Expect = 3e-04
Identities = 58/249 (23%), Positives = 105/249 (42%), Gaps = 36/249 (14%)
Query: 146 ESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIM 205
ES LL L + E+ D L R T A +++ + +A F+ L + I+
Sbjct: 589 ESLLLCTLN---DREISMEDEATTLFRATTLASTLMEQYMKA---TATQFVHHALKDSIL 642
Query: 206 QLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKF 265
+++ E + E P+KL EK D V +N L+ ++++
Sbjct: 643 KIM-ESKQSCELSPSKL--------------EKNED---------VNTNLTHLLNILSEL 678
Query: 266 IGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQY 325
+ + + P +LR+I + K++ + + + ICPA++NP +
Sbjct: 679 VEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMF 738
Query: 326 GIISDAPINEVARFNLMQVGRLLQQLAMT---GSEEGDPRTKSSLGKFDKSCVAAFLDVV 382
IISD+P + +A L+ V + +Q LA G++E + K +K + FLD +
Sbjct: 739 NIISDSP-SPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDEL 797
Query: 383 IGGRAVETP 391
G E P
Sbjct: 798 --GNVPELP 804
>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
Length = 631
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 23/121 (19%)
Query: 1382 PWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVP--------------- 1426
P+ +A E+ + P+ K++CI+R + ++ + ED P
Sbjct: 508 PYCAAAQELGLLVLESCPQKKLECIVRT----LRIICVCAEDYCPTPEATPQAGPPPIAA 563
Query: 1427 ---GADDFVPVLVFVLIKANPPCLLSTVQYISSF-YASCLSGEESYWWMQFTAAVEFIKT 1482
GADD +P+L FV++++ P L+S + F + L GEE Y +A+ +++
Sbjct: 564 AAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVEL 623
Query: 1483 I 1483
+
Sbjct: 624 L 624
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 41.2 bits (95), Expect = 0.008
Identities = 62/322 (19%), Positives = 110/322 (34%), Gaps = 56/322 (17%)
Query: 722 SDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIPNK 781
S+ E P + L+EL+ L + +D+ T L+ S E N
Sbjct: 289 SEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN----FSDDDEQGSNS 344
Query: 782 IEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQLSSSAHQL 841
++ SE +++ + DE+++ + S+ Q+
Sbjct: 345 PKENNSEDQGSKASENNENKKETDEVSN-------------------------TKSSSQI 379
Query: 842 TSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPNF 901
+ PS ++ + G S+ + P HPPPD + G G F
Sbjct: 380 PAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPG-------PF 432
Query: 902 GSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPA-- 959
S E E +KQR R + S+I ++V R R E+R+ A
Sbjct: 433 PSKQQVADEDEIWKQR--------RRQQSEISAAVERARKRREEEERRMEEQRKAACAEK 484
Query: 960 -----AAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEK-----SDRNRPWWRKRF 1009
+G +P + E E K+ + E+ DR R +++
Sbjct: 485 LKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKE 544
Query: 1010 VSAMPKAPIPFRKKEKQEKDKD 1031
+ + K+ KQEK+K+
Sbjct: 545 LEKEQEKQREMEKERKQEKEKE 566
Score = 33.9 bits (76), Expect = 1.2
Identities = 51/240 (21%), Positives = 87/240 (36%), Gaps = 30/240 (12%)
Query: 773 ATSEDIPNKIEDLRSECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRI 832
AT+ + ED+RSE + D ++ +T+ + H+ L PK F +EA ++
Sbjct: 820 ATTPKATEEPEDVRSEAALD---QEQITAAY--SVEHNQLEA-HPKADFIRESSEAQVQK 873
Query: 833 QLSSSAHQLTSPPSQSESLLAMFDP-------LSSHEGASAVVRPKVHYARPSH-----P 880
LS S + + + + A F+ E SAV SH
Sbjct: 874 FLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQ 933
Query: 881 PPDPPILEGAVGGNEARLPNFGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPM 940
PD E + G +P S + E + E +RS V +
Sbjct: 934 KPDEQRSEPSAG-----IPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSK 988
Query: 941 SDPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDR 1000
S+ W RP + RE + + + P + E E+RK+ + EK+++
Sbjct: 989 SETRWGPRPSSNRREEVNDRPVRRSGPI-------KKPVLRDMKEEREQRKEKEGEKAEK 1041
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 40.8 bits (94), Expect = 0.010
Identities = 78/340 (22%), Positives = 130/340 (38%), Gaps = 37/340 (10%)
Query: 561 KTLRFSLCSDNLEGISEGPSNRSNS-----VSSLDLEGESVSELGAGPS--GSNGVE-AL 612
K LR S D + SE +R + ++ D +G V A P S G E
Sbjct: 979 KRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEK 1038
Query: 613 QLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDR 672
+ L EQ +T++ + + + E D +DDRD SE E + + + DE+
Sbjct: 1039 ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Query: 673 LQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWSVEVLPSDSEAPDLKQE 732
I + AE S S S + + S+ S + E EV+ + E + ++E
Sbjct: 1099 TVSIVTSKAEATSSS----ESSESSEFESSSESSPSSSEDEE---EVVAREEE--EEEEE 1149
Query: 733 ERLQELESCSGLGSTSDDTDVREVSSRPSTP---GLSVVSGISATSEDI-PNKIEDLRSE 788
E + ES + G + D E + P P L + + +E + P + + E
Sbjct: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE 1209
Query: 789 CSSDFGGK---DSVTSPDMDEITHDFLYILQPKQHFQHIEAEADMRIQLSSSAHQLTSPP 845
G + DS P+ ++ + +L P+ + +EA + + + H L P
Sbjct: 1210 PPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE-RAPEHDLEVEP 1268
Query: 846 SQSESL-LAMFDPLSSHEGASAVVRPKVHYARPSHPPPDP 884
L L + PL P RP PPP+P
Sbjct: 1269 EPPMMLPLPLQPPL-----------PPPRPPRPPSPPPEP 1297
Score = 34.3 bits (77), Expect = 0.92
Identities = 31/140 (22%), Positives = 54/140 (38%), Gaps = 23/140 (16%)
Query: 962 IGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPFR 1021
+G A P S +D +EE++ +++E+
Sbjct: 1017 VGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAE--------------------- 1055
Query: 1022 KKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMA--N 1079
++E++E D DD DR + DD LS ++ E D+ TS ++ + +
Sbjct: 1056 EEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES 1115
Query: 1080 YESTEVMGDGESAHDSPRDE 1099
ES+E ES+ S DE
Sbjct: 1116 SESSEFESSSESSPSSSEDE 1135
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 39.7 bits (91), Expect = 0.022
Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 33/189 (17%)
Query: 165 DNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIE 224
DN + R T A + + + +L L E ++ L E +++ E DP+K
Sbjct: 282 DNEHLIFRENTLATKAIEEYLK---LVGQKYLQDALGE-FIKALYESDENCEVDPSKCSA 337
Query: 225 RFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYC-FPHSLRWI 283
P Q L + E K++ N+YC FP L+ +
Sbjct: 338 ADLPEHQGNL-------------KMCCELAFCKII------------NSYCVFPRELKEV 372
Query: 284 VSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQ 343
+ + S R ++ E R + L L F+CPA+++P + ++ + P + AR L
Sbjct: 373 FASWRQECSSRGRPDISE-RLISASLFLR-FLCPAIMSPSLFNLLQEYPDDRTAR-TLTL 429
Query: 344 VGRLLQQLA 352
+ ++ Q LA
Sbjct: 430 IAKVTQNLA 438
>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
sapiens]
Length = 1132
Score = 39.7 bits (91), Expect = 0.022
Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 33/189 (17%)
Query: 165 DNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIE 224
DN + R T A + + + +L L E ++ L E +++ E DP+K
Sbjct: 378 DNEHLIFRENTLATKAIEEYLK---LVGQKYLQDALGE-FIKALYESDENCEVDPSKCSA 433
Query: 225 RFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYC-FPHSLRWI 283
P Q L + E K++ N+YC FP L+ +
Sbjct: 434 ADLPEHQGNL-------------KMCCELAFCKII------------NSYCVFPRELKEV 468
Query: 284 VSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQ 343
+ + S R ++ E R + L L F+CPA+++P + ++ + P + AR L
Sbjct: 469 FASWRQECSSRGRPDISE-RLISASLFLR-FLCPAIMSPSLFNLLQEYPDDRTAR-TLTL 525
Query: 344 VGRLLQQLA 352
+ ++ Q LA
Sbjct: 526 IAKVTQNLA 534
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 38.9 bits (89), Expect = 0.037
Identities = 52/231 (22%), Positives = 84/231 (36%), Gaps = 9/231 (3%)
Query: 576 SEGPSNRSNSVSSLDLEGESVSELGAGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEI 635
S S+ S+S +S D S S G+ SN ++ + ++ N D +
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 636 RDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSG 695
+ +D D S + S++ S+D S + + +++N S
Sbjct: 886 NESSNSSDSSDSSNS-SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 696 SVLLDPCTGSTISETTSEAWSVEVLPSDSEAPDLKQEERLQELESCSGLGSTSDDTDVRE 755
S D S S ++ + S + SDS + D + S +SD +D
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSD--SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD--- 999
Query: 756 VSSRPSTPGLSVVSGISATSEDIPNKIEDLRSECSSDFGGKDSVTSPDMDE 806
SS S S S S+ S D N + S SSD DS S D +
Sbjct: 1000 -SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD--SSDSSDSSDSSD 1047
Score = 36.6 bits (83), Expect = 0.19
Identities = 59/270 (21%), Positives = 100/270 (37%), Gaps = 17/270 (6%)
Query: 541 SDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLE-GESVSEL 599
SD D + N + DK+ SD+ + S SN S+S S D + +S S
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578
Query: 600 GAGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDV 659
+ S S+ ++ + + + D+ D D +D D S++ S++ ++
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSS-------DSSDSSDSSDSSDSKSDSSKSES 631
Query: 660 LGSDFD---PNIDEDRLQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWS 716
SD D + D + + + + S S S + S+ S +S++
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 717 VEVLPSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSE 776
+ SE+ D +S S S D+D SS S S S S+ S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD----SSNSSDSSDSSNSSDSSDSS 747
Query: 777 DIPNKIEDLRSECSSDFGGKDSVTSPDMDE 806
D N + S+ S DS S D +
Sbjct: 748 DSSNSSDS--SDSSDSSNSSDSSDSSDSSD 775
Score = 33.9 bits (76), Expect = 1.2
Identities = 40/199 (20%), Positives = 70/199 (35%), Gaps = 25/199 (12%)
Query: 927 SRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGE 986
S SSD S SD + + + + + ++ ++ + SS SS S DSS
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--- 614
Query: 987 TEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPFRKKEKQEKDKDDLGPDRFSTLTDDPS 1046
+ DS D KSD + K E D D S +D
Sbjct: 615 --DSSDSSDSKSDSS--------------------KSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 1047 PRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANYESTEVMGDGESAHDSPRDEALQNISA 1106
S+ + + + D ++ S S +N + D ++ +S + +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712
Query: 1107 DDLPDSASQAAHPQDSAFS 1125
D DS++ + DS+ S
Sbjct: 713 SDSSDSSNSNSSDSDSSNS 731
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 38.9 bits (89), Expect = 0.037
Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 6/118 (5%)
Query: 921 PERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPA--AAIGATSLVAAPHSSSSSP 978
PER +++ + ++ S S + EE + PPA AA+ A + P +++
Sbjct: 64 PERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKA 123
Query: 979 SKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPFRKKEKQEKDKDDLGPD 1036
S+ SS +EE D DDE+ + +P +K A P +K + + D D D
Sbjct: 124 SESSS---SEESSDDDDEEDQKKQP-VQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Score = 35.4 bits (80), Expect = 0.41
Identities = 45/189 (23%), Positives = 69/189 (36%), Gaps = 23/189 (12%)
Query: 921 PERLVRSRSSDIVSSVRRPMSDPSWNRRPG------NEERELPPAAAIGATSLVAAPHSS 974
P + +S SD SS +P N++P + + PP A A + +S
Sbjct: 160 PPKKAKSSDSDSDSSSE---DEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAAS 216
Query: 975 SSSPSKDSSRGETEERKDSDDEK--SDRNRPWWRKRFVSAMP--KAPIPFRKKEKQEKDK 1030
SSS S SS + DS++EK + + +K+ V+ P A P RK E
Sbjct: 217 SSSSSSSSSSSD-----DSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSS 271
Query: 1031 DDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANYESTEVMGDGE 1090
D ++ + + P P S A T P A+ + E D
Sbjct: 272 SDEEEEQKKPMKNKPGPYSSVPPPSAPP-----PKKSLGTQPPKKAVEKQQPVESSEDSS 326
Query: 1091 SAHDSPRDE 1099
DS +E
Sbjct: 327 DESDSSSEE 335
Score = 35.4 bits (80), Expect = 0.41
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 23/246 (9%)
Query: 903 SHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAAAI 962
S V P+ K + P + + + SS D S +EE + PP A+
Sbjct: 290 SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS-----EDSSDESDSSSEEEKKPPTKAV 344
Query: 963 GATSLVAAP------HSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRF----VSA 1012
+ + P SSS S DSS + K + K+ N+P + +A
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAA 404
Query: 1013 MPKAPIP------FRKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNA 1066
PK P+ RK + +++ + T + + A A+ A + K
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ 464
Query: 1067 IKRTSPSDGAMANYESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSY 1126
R S SD ++ E E + P+ A +A P SA + ++ S
Sbjct: 465 GSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA--GGAAPSKPASAKKGKAESSNSSSS 522
Query: 1127 RDAKKK 1132
D+ ++
Sbjct: 523 DDSSEE 528
Score = 35.0 bits (79), Expect = 0.54
Identities = 81/414 (19%), Positives = 146/414 (35%), Gaps = 45/414 (10%)
Query: 740 SCSGLGSTSDDTDVREVSSRP--STPGLSVVSGI-----------SATSEDIPNKIEDLR 786
S S S+SDD++ + ++ P + P VV+ S++SED + E+ +
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ 278
Query: 787 SECSSDFGGKDSVTSPDMDEITHDFLYILQPKQHF---QHIEAEADMRIQLSSSAHQLTS 843
+ + G S P L PK+ Q +E+ D + SS+ +
Sbjct: 279 KKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKK 338
Query: 844 PPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPNFGS 903
PP+++ A P + + A + + P P N+ + S
Sbjct: 339 PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTT-KS 397
Query: 904 HVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAAAIG 963
+ PA A KQ ++L+ ++ D S + + E +
Sbjct: 398 PAVKPAA--APKQPVGGGQKLLTRKA------------DSSSSEEESSSSEEEKTKKMVA 443
Query: 964 ATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPFRKK 1023
T A ++ S P+K + +G + DSD S+ K V P+
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503
Query: 1024 EKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANYEST 1083
K K S+ +DD S E+ +K + K + AN S
Sbjct: 504 SKPASAKKGKAESSNSSSSDDSS----------EEEEEKLKG--KGSPRPQAPKANGTSA 551
Query: 1084 EVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDA--KKKLRL 1135
+G++A +S +E + +A + S S Q+ A + KK++L
Sbjct: 552 LTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKL 605
Score = 34.7 bits (78), Expect = 0.71
Identities = 69/338 (20%), Positives = 113/338 (33%), Gaps = 51/338 (15%)
Query: 843 SPPSQSESLLAMFDPLSSHE---GASAVVRPKVHYARPSHPPPD----PPILEGAVGGNE 895
+PP +++S + D S E + P A+ PP P I G +
Sbjct: 159 APPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSS 218
Query: 896 ARLPNFGSHVLTPAEMEAFKQRHSYPERLV--------------RSRSSDIVSSVRRPMS 941
+ + S + E A + + P++ V +S SS+ SS
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ 278
Query: 942 DPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRN 1001
+PG PP+A SL P + K +E+ D D S+
Sbjct: 279 KKPMKNKPGPYSSVPPPSAPPPKKSLGTQP--PKKAVEKQQPVESSEDSSDESDSSSEEE 336
Query: 1002 RPWWRKRFVSAMPKAPIPFRKKEKQEKD-------KDDLGPDRFSTLTDDPS-------- 1046
+ K VS P P +K + D +DD P + + T + S
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTK 396
Query: 1047 -----PRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANYESTEVM-------GDGESAHD 1094
P + + V R A +S + + + E T+ M ++A
Sbjct: 397 SPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALS 456
Query: 1095 SPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKK 1132
P +A Q S D DS S ++ ++ S KKK
Sbjct: 457 LPAKQAPQG-SRDSSSDSDSSSSEEEEEKTSKSAVKKK 493
>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
Length = 783
Score = 38.9 bits (89), Expect = 0.037
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 1398 TPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF 1457
+P +V+ +L+ C + L E GAD+F+P+L VL + P LL +Y+S
Sbjct: 507 SPSAQVKRLLQACKLLYMALR-TQEGEGAGADEFLPLLSLVLAHCDLPELLLEAEYMSEL 565
Query: 1458 Y-ASCLSGEESYWWMQFTAAVEFI 1480
S L+GE Y+ +A++ +
Sbjct: 566 LEPSLLTGEGGYYLTSLSASLALL 589
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 38.9 bits (89), Expect = 0.037
Identities = 70/295 (23%), Positives = 117/295 (39%), Gaps = 21/295 (7%)
Query: 718 EVLPSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSED 777
EV S+ + D + EE + LE + D +V E + S V + S++
Sbjct: 371 EVRESEKQQ-DSQPEEVMDVLEMVENVKHVIADQEVMETNRVES-----VEPSENEASKE 424
Query: 778 IPNKIE---DLRSECSSDFGGKDSVTSPDMD---EITHDFLYILQPKQHFQ-HIEAEADM 830
+ ++E + EC S GK++V++ DM+ E + QP+ Q +++ +
Sbjct: 425 LEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQL 484
Query: 831 RIQLSSSAHQLTSPPSQSESL-LAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEG 889
++Q S + PPSQ E L LA+ P + P+ R P + E
Sbjct: 485 QLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPE----RKDFPVESVKLTEV 540
Query: 890 AVGGNEARLPNFGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRP 949
V P S T + + R+ + RS SS SS S S +
Sbjct: 541 PVEPVLTVHPESKSKTKTRSRSRG-RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSG 599
Query: 950 GNEERELPPAAAI--GATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNR 1002
+ R +++ G++S ++ +SSSS S+ SRG R DR R
Sbjct: 600 SSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKR 654
>gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]
Length = 1024
Score = 38.5 bits (88), Expect = 0.049
Identities = 48/169 (28%), Positives = 64/169 (37%), Gaps = 28/169 (16%)
Query: 877 PSHPPPDPPILEGAVGGNEA--RLPNFGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVS 934
P PP PP + G A R + L + +++ E L +D S
Sbjct: 257 PEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRET-DIDEVLAEREEAD--S 313
Query: 935 SVRRPMSDPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSD 994
++ S PS PG PPA G + PH S S ++D E +D D
Sbjct: 314 AIE---SQPSSEGPPGTA---YPPAPRPGP---LPGPHPSLGSGNEDEDDDEAGGEEDVD 364
Query: 995 D---EKSDRNRPWWRKRFVSAMP-KAPIPFRKKEKQEKDKDDLGPDRFS 1039
D E S+ RP S MP K+P+PF D GPD FS
Sbjct: 365 DEVFEASEGARPG------SRMPLKSPVPFLPGTSPSAD----GPDSFS 403
>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
Length = 2839
Score = 37.7 bits (86), Expect = 0.083
Identities = 62/279 (22%), Positives = 111/279 (39%), Gaps = 68/279 (24%)
Query: 149 LLQVLRYLIEFELKESDNPRRLLRRGTCAFSIL---FKLFSEGLFSAKLFLTATLHEPIM 205
L Q+L + E++ +D+ + L R + A I+ FK++ L +P++
Sbjct: 1253 LYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLL-------DPLL 1305
Query: 206 QLLVEDED----HLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVAL 261
++++ D E DP +L PS E +E N+ L+ +
Sbjct: 1306 RIVITSSDWQHVSFEVDPTRL----EPS-------------------ESLEENQRNLLQM 1342
Query: 262 VNKFIGYLKQNTYCFPHSLRWIVSQMYKTL--SCVDRLEVGE-----------------V 302
KF + ++ FP LR + +Y+ S +++ V E +
Sbjct: 1343 TEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSI 1402
Query: 303 RAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLA----MTGSEE 358
A+ + + L FI PA+V+P + GI+ P + R L + ++LQ +A T E
Sbjct: 1403 GAVGSAMFLR-FINPAIVSPYEAGILDKKPPPRIER-GLKLMSKILQSIANHVLFTKEEH 1460
Query: 359 GDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVN 397
P FD + FLD+ A + P +VN
Sbjct: 1461 MRPFNDFVKSNFD-AARRFFLDI-----ASDCPTSDAVN 1493
>gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
Length = 621
Score = 37.7 bits (86), Expect = 0.083
Identities = 38/163 (23%), Positives = 64/163 (39%), Gaps = 17/163 (10%)
Query: 843 SPPSQSESLLAMFDPLSSHEGASAVVRPKV-HYARPSHPPPDPPILEGAVGGNEARLPNF 901
SPP + DPL++ +P++ H+ + + P + + G G EA LP
Sbjct: 319 SPPQKRLQPPDFIDPLANK-------KPRISHFTQRAQPAVNGKL--GVPNGREALLPTP 369
Query: 902 GSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAAA 961
G PA + P RL R+ D ++ V + + G E P
Sbjct: 370 GP----PASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHG-EAAAPAPTVR 424
Query: 962 IGATSLV--AAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNR 1002
+G L A P SPS+ + ++++ KD + D+ R
Sbjct: 425 LGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPR 467
>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo
sapiens]
Length = 1343
Score = 37.7 bits (86), Expect = 0.083
Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 272 NTYC-FPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISD 330
N++C FP L+ + + L C +R + + L F+CPA+++P +G++ +
Sbjct: 556 NSHCVFPRELKEVFASW--RLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQE 613
Query: 331 APINEVARFNLMQVGRLLQQLA 352
P + +R L + +++Q LA
Sbjct: 614 YPDEQTSR-TLTLIAKVIQNLA 634
>gi|8923771 ELG protein isoform b [Homo sapiens]
Length = 340
Score = 37.4 bits (85), Expect = 0.11
Identities = 36/176 (20%), Positives = 63/176 (35%), Gaps = 17/176 (9%)
Query: 965 TSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSA-MPKAPIPFRKK 1023
+ LV P ++ E EE +D D + DR + + + P+ R+
Sbjct: 53 SGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS 112
Query: 1024 EKQEKDKDDLGPDRFSTLTDDPSPRLSAQ----AQVAEDILDKYRNAIKRTSPSDGAMAN 1079
D D++ D + PSP+ S + A E L RN+++ S S + N
Sbjct: 113 SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKN 172
Query: 1080 ----------YESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFS 1125
+ + D + H PR + + D+ + H + AFS
Sbjct: 173 RIGNKLPPEKFADVRHLLDEKRQHSRPRPPV--SSTKSDIRQRLGKRPHSPEKAFS 226
>gi|166295179 ELG protein isoform a [Homo sapiens]
Length = 620
Score = 37.4 bits (85), Expect = 0.11
Identities = 36/176 (20%), Positives = 63/176 (35%), Gaps = 17/176 (9%)
Query: 965 TSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSA-MPKAPIPFRKK 1023
+ LV P ++ E EE +D D + DR + + + P+ R+
Sbjct: 333 SGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS 392
Query: 1024 EKQEKDKDDLGPDRFSTLTDDPSPRLSAQ----AQVAEDILDKYRNAIKRTSPSDGAMAN 1079
D D++ D + PSP+ S + A E L RN+++ S S + N
Sbjct: 393 SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKN 452
Query: 1080 ----------YESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFS 1125
+ + D + H PR + + D+ + H + AFS
Sbjct: 453 RIGNKLPPEKFADVRHLLDEKRQHSRPRPPV--SSTKSDIRQRLGKRPHSPEKAFS 506
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 37.4 bits (85), Expect = 0.11
Identities = 56/246 (22%), Positives = 84/246 (34%), Gaps = 18/246 (7%)
Query: 957 PPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKA 1016
PP ATSL SS PS D + + S+ KS P + + + A A
Sbjct: 809 PPGPITTATSLY------SSDPSADLKKASSSNAAKSNLPKSGLRPPGYSR--LPAAKLA 860
Query: 1017 PIPFRKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGA 1076
F + D P+ R S + +L K K T G
Sbjct: 861 AFGFVRSSSVSSVSSTQSGDSAQPEQGRPATR-STFGNEEQPVL-KASLPSKDTPKGAGR 918
Query: 1077 MANYESTEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKKLRLA 1136
+A S+ V S +P+ S + A QD+ + K++ +
Sbjct: 919 VAPPASSSVTAPRRSLLPAPK-------STSTPAGTKKDAQKDQDTNKPAVSSPKRVAAS 971
Query: 1137 LCSADSVAFPVL-THSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMR 1195
S +P T + RNG P DP+ E L +++ E Q + L E R
Sbjct: 972 TTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKR 1031
Query: 1196 CVCRFD 1201
+C FD
Sbjct: 1032 AICGFD 1037
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 37.4 bits (85), Expect = 0.11
Identities = 55/214 (25%), Positives = 80/214 (37%), Gaps = 27/214 (12%)
Query: 939 PMSDPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKS 998
P P+W R + R P + ++ P S+S+SP S + R E+
Sbjct: 330 PGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERG 389
Query: 999 DRNRP--WWRKRFVSAMPKAPIPFRKKEKQ------EKDKDDLGPDRF----STLTDDPS 1046
+R +P V P+A P +KKEK+ EK+K L +R +L P
Sbjct: 390 ERRKPNAGGSPAPVRRRPEAS-PVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPR 448
Query: 1047 PRLSAQAQVAEDILDKYRNAIKRTS--------PSDGAMANYESTEVMGDGESAHDSPRD 1098
RLSA K R + TS PS G G +A SP+
Sbjct: 449 ARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTA--SPKG 506
Query: 1099 EALQNISADDLPDSASQAAHPQDSAFSYRDAKKK 1132
+ A + P AA P+D + S R A +
Sbjct: 507 RVRRKEEAKESP----SAAGPEDKSQSKRRASNE 536
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 37.0 bits (84), Expect = 0.14
Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 10/141 (7%)
Query: 939 PMSDPSWNRRPGN--EERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKD-SDD 995
P S W R PG E R PP A + AP SS S S + G+T ERK+ +
Sbjct: 1270 PSSSSDW-RVPGQGLENRGEPPTPPSPAPAPAVAPGGSSES-SSGRAAGDTPERKEAAGT 1327
Query: 996 EKSDRNRPWWRKRFVSAMPKAPIPFRKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQV 1055
K + RP K+ ++ + E++ + + P+ PSP L + A
Sbjct: 1328 GKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVL-----PSPTLQSLATS 1382
Query: 1056 AEDILDKYRNAIKRTSPSDGA 1076
IL YR K ++ D A
Sbjct: 1383 PRAILGSYRKKRKNSTDLDSA 1403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,921,907
Number of Sequences: 37866
Number of extensions: 2652199
Number of successful extensions: 11848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 11336
Number of HSP's gapped (non-prelim): 605
length of query: 1487
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1372
effective length of database: 13,892,928
effective search space: 19061097216
effective search space used: 19061097216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.