Guide to the Human Genome
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Name: NF1 Sequence: fasta or formatted (2839aa) NCBI GI: 109826564
Description:

neurofibromin isoform 1

Referenced in:

Adrenals
Ras
RNA Metabolism

Other entries for this name:
alt prot [593aa] neurofibromin isoform 3
alt prot [2818aa] neurofibromin isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6        188           2
 C cysteine            2.2         63           1
 D aspartate           4.5        129           3
 E glutamate           6.1        172           2
 F phenylalanine       4.2        119           2
 G glycine             4.2        120           3
 H histidine           3.1         88           2
 I isoleucine          5.2        148           2
 K lysine              6.2        175           2
 L leucine            12.5        355           3
 M methionine          2.9         82           2
 N asparagine          4.6        132           2
 P proline             4.2        120           3
 Q glutamine           4.5        127           2
 R arginine            4.3        121           2
 S serine              8.6        243           4
 T threonine           6.2        176           2
 V valine              6.3        180           2
 W tryptophan          1.1         32           2
 Y tyrosine            2.4         69           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neurofibromin isoform 1 
NF1                   0.990   neurofibromin isoform 2 
NF1                   0.201   neurofibromin isoform 3 
DAB2IP                0.015   disabled homolog 2 interacting protein isoform 2 [Ho...
DAB2IP                0.015   disabled homolog 2 interacting protein isoform 1 [Ho...
RASA1                 0.014   RAS p21 protein activator 1 isoform 1 
RASA1                 0.014   RAS p21 protein activator 1 isoform 2 
RASAL2                0.014   RAS protein activator like 2 isoform 2 
RASAL2                0.014   RAS protein activator like 2 isoform 1 
RASA3                 0.013   RAS p21 protein activator 3 
SYNGAP1               0.012   synaptic Ras GTPase activating protein 1 
RASA2                 0.011   RAS p21 protein activator 2 
RASAL3                0.011   RAS protein activator like 3 
RASAL1                0.009   RAS protein activator like 1 
RASA4                 0.008   RAS p21 protein activator 4 isoform 2 
RASA4                 0.008   RAS p21 protein activator 4 isoform 1 
LOC100132214          0.008   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.008   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.008   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.008   PREDICTED: similar to calcium-promoted Ras inactiva...
IQGAP2                0.007   IQ motif containing GTPase activating protein 2 [Ho...
IQGAP1                0.007   IQ motif containing GTPase activating protein 1 [Homo...
IQGAP3                0.006   IQ motif containing GTPase activating protein 3 [Hom...
GDAP2                 0.003   ganglioside induced differentiation associated prot...
GDAP2                 0.002   ganglioside induced differentiation associated protei...
GAPVD1                0.002   GTPase activating protein and VPS9 domains 1 
ABCA13                0.002   ATP binding cassette, sub-family A (ABC1), member 13...
FRY                   0.001   furry homolog 
FRYL                  0.001   furry-like 
TNS1                  0.001   tensin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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