Guide to the Human Genome
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Name: LMNA Sequence: fasta or formatted (572aa) NCBI GI: 5031875
Description:

lamin A/C isoform 2

Referenced in:

Cytoskeleton
Nucleus and Nucleolus
Prenylation and Related Modifications

Other entries for this name:
alt prot [664aa] lamin A/C isoform 1 precursor
alt prot [634aa] lamin A/C isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.3         53           2
 C cysteine            0.2          1           1
 D aspartate           5.8         33           2
 E glutamate          12.2         70           3
 F phenylalanine       1.2          7           1
 G glycine             4.7         27           3
 H histidine           2.1         12           4
 I isoleucine          2.4         14           1
 K lysine              6.8         39           2
 L leucine            11.9         68           2
 M methionine          1.6          9           1
 N asparagine          3.0         17           1
 P proline             1.7         10           2
 Q glutamine           6.3         36           3
 R arginine           10.5         60           2
 S serine              8.4         48           2
 T threonine           5.2         30           1
 V valine              4.5         26           2
 W tryptophan          0.7          4           1
 Y tyrosine            1.4          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lamin A/C isoform 2 
LMNA                  0.991   lamin A/C isoform 1 precursor 
LMNA                  0.933   lamin A/C isoform 3 
LMNB1                 0.545   lamin B1 
LMNB2                 0.536   lamin B2 
DES                   0.136   desmin 
PRPH                  0.132   peripherin 
VIM                   0.129   vimentin 
NEFL                  0.121   neurofilament, light polypeptide 68kDa 
GFAP                  0.117   glial fibrillary acidic protein isoform 1 
NEFM                  0.116   neurofilament, medium polypeptide 150kDa isoform 1 ...
INA                   0.114   internexin neuronal intermediate filament protein, a...
GFAP                  0.114   glial fibrillary acidic protein isoform 2 
KRT8                  0.110   keratin 8 
KRT18                 0.110   keratin 18 
KRT18                 0.110   keratin 18 
KRT75                 0.106   keratin 75 
NEFH                  0.103   neurofilament, heavy polypeptide 200kDa 
KRT5                  0.102   keratin 5 
KRT6C                 0.099   keratin 6C 
KRT3                  0.098   keratin 3 
KRT6A                 0.097   keratin 6A 
KRT6B                 0.096   keratin 6B 
KRT4                  0.096   keratin 4 
KRT16                 0.096   keratin 16 
KRT78                 0.095   keratin 5b 
KRT1                  0.093   keratin 1 
KRT7                  0.093   keratin 7 
KRT14                 0.092   keratin 14 
KRT80                 0.091   keratin 80 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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