BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4826694 integral membrane protein DGCR2 [Homo sapiens] (550 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4826694 integral membrane protein DGCR2 [Homo sapiens] 1175 0.0 gi|119709832 low density lipoprotein receptor-related protein 5 ... 65 1e-10 gi|148727288 low density lipoprotein receptor-related protein 6 ... 63 8e-10 gi|144446030 lymphocyte antigen 75 [Homo sapiens] 56 1e-07 gi|61744471 low density lipoprotein receptor-related protein 8 i... 51 2e-06 gi|65301119 low density lipoprotein receptor-related protein 8 i... 51 2e-06 gi|28557796 low density lipoprotein receptor class A domain cont... 51 3e-06 gi|4504975 low density lipoprotein receptor precursor [Homo sapi... 50 4e-06 gi|11415040 matriptase [Homo sapiens] 50 5e-06 gi|46410931 attractin-like 1 [Homo sapiens] 50 7e-06 gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 48 2e-05 gi|29244926 corin [Homo sapiens] 48 2e-05 gi|65301164 very low density lipoprotein receptor isoform b [Hom... 48 2e-05 gi|65301167 very low density lipoprotein receptor isoform a [Hom... 48 2e-05 gi|157384998 low density lipoprotein receptor-related protein 4 ... 48 3e-05 gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 48 3e-05 gi|134031945 SCO-spondin [Homo sapiens] 47 5e-05 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 47 6e-05 gi|61744467 low density lipoprotein receptor-related protein 8 i... 45 2e-04 gi|66082554 low density lipoprotein receptor-related protein 8 i... 45 2e-04 gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho... 45 2e-04 gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho... 45 2e-04 gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho... 45 2e-04 gi|93102379 low density lipoprotein-related protein 1B precursor... 45 2e-04 gi|167555125 low density lipoprotein receptor-related protein 3 ... 44 4e-04 gi|4507157 sortilin-related receptor containing LDLR class A rep... 44 4e-04 gi|7706111 8D6 antigen [Homo sapiens] 44 4e-04 gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom... 43 7e-04 gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom... 43 7e-04 gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 43 7e-04 >gi|4826694 integral membrane protein DGCR2 [Homo sapiens] Length = 550 Score = 1175 bits (3040), Expect = 0.0 Identities = 550/550 (100%), Positives = 550/550 (100%) Query: 1 MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDE 60 MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDE Sbjct: 1 MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDE 60 Query: 61 SDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWH 120 SDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWH Sbjct: 61 SDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWH 120 Query: 121 HYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKD 180 HYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKD Sbjct: 121 HYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKD 180 Query: 181 QRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFH 240 QRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFH Sbjct: 181 QRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFH 240 Query: 241 FPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHG 300 FPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHG Sbjct: 241 FPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHG 300 Query: 301 GEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLI 360 GEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLI Sbjct: 301 GEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLI 360 Query: 361 LSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGE 420 LSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGE Sbjct: 361 LSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGE 420 Query: 421 GGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAP 480 GGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAP Sbjct: 421 GGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAP 480 Query: 481 GDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGR 540 GDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGR Sbjct: 481 GDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGR 540 Query: 541 HSRSSLNTVV 550 HSRSSLNTVV Sbjct: 541 HSRSSLNTVV 550 >gi|119709832 low density lipoprotein receptor-related protein 5 [Homo sapiens] Length = 1615 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Query: 3 PKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESD 62 P+ L+L +LT EP C+P QFAC +G I CIP W+CDG+ C+D+SD Sbjct: 1236 PRCSCPVHLVLLQNLLTCGEPPT----CSPDQFACATGEIDCIPGAWRCDGFPECDDQSD 1291 Query: 63 EANCPEVTGEVRPHHGKEAVDPR 85 E CP + P + VD R Sbjct: 1292 EEGCPVCSAAQFPCARGQCVDLR 1314 Score = 40.0 bits (92), Expect = 0.006 Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 3/41 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C P QF C SG QC+ + QCD + C D SDE C E+T Sbjct: 1336 CLPNQFRCASG--QCVLIKQQCDSFPDCIDGSDELMC-EIT 1373 >gi|148727288 low density lipoprotein receptor-related protein 6 [Homo sapiens] Length = 1613 Score = 62.8 bits (151), Expect = 8e-10 Identities = 23/38 (60%), Positives = 28/38 (73%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C+P QF C +G I CIP+ W+CDG+ CED SDE NCP Sbjct: 1249 CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCP 1286 Score = 33.9 bits (76), Expect = 0.40 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 27 ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E+ C QF C +G QCI +CD C D+SDE +C Sbjct: 1323 EVLCLIDQFRCANG--QCIGKHKKCDHNVDCSDKSDELDC 1360 >gi|144446030 lymphocyte antigen 75 [Homo sapiens] Length = 1722 Score = 55.8 bits (133), Expect = 1e-07 Identities = 42/162 (25%), Positives = 69/162 (42%), Gaps = 27/162 (16%) Query: 115 CPTGWHHYEGTASCYRVY-----LSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEW 169 CP GW + + SCY+V+ + N+ +A + CQ L L++FS E++ L Sbjct: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702 Query: 170 DQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSEND 229 DQ + Q LW+G + R+ L+G W+ + + + P+ + D Sbjct: 703 DQ------FSGQHWLWIG----LNKRSPDLQGSWQWSDRTPVSTIIMPNEF----QQDYD 748 Query: 230 NVFCAQLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTC 271 CA ++ FH P R WH Y+ F+ R C Sbjct: 749 IRDCAAVKVFHRPWRR-----GWH---FYDDREFIYLRPFAC 782 >gi|61744471 low density lipoprotein receptor-related protein 8 isoform 1 precursor [Homo sapiens] Length = 963 Score = 51.2 bits (121), Expect = 2e-06 Identities = 22/42 (52%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P QFACRSG +C+ L W+CDG C+D+SDEA+CP Sbjct: 256 PAACATASQFACRSG--ECVHLGWRCDGDRDCKDKSDEADCP 295 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 9 AFLLLFLLVLTV---------TEPLR----PELRCNPGQFACRSGTIQCIPLPWQCDGWA 55 A LLL LL+L + +PL P C QF CR+ +CIP W+CD Sbjct: 13 ALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNE--RCIPSVWRCDEDD 70 Query: 56 TCEDESDEANCPEVT 70 C D SDE +CP+ T Sbjct: 71 DCLDHSDEDDCPKKT 85 Score = 39.3 bits (90), Expect = 0.009 Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C + +C + +C+P W+CDG CE +DEA C Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163 Score = 37.7 bits (86), Expect = 0.027 Identities = 18/36 (50%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 30 CNPGQFACRS-GTIQCIPLPWQCDGWATCEDESDEA 64 C P +F C G CIP W CD CED SDEA Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEA 241 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 P+ C F C +G CI W+CDG C D SDE+ Sbjct: 82 PKKTCADSDFTCDNG--HCIHERWKCDGEEECPDGSDES 118 Score = 33.1 bits (74), Expect = 0.68 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 14/64 (21%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGRA 89 C P +F C G C+ + CDG C D SDE C + A PR+ R Sbjct: 167 CAPHEFQC--GNRSCLAAVFVCDGDDDCGDGSDERGCAD-----------PACGPREFRC 213 Query: 90 RGGD 93 GGD Sbjct: 214 -GGD 216 Score = 30.0 bits (66), Expect = 5.7 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHG 78 C +F C GT C+ C+ C D SDEA C + E ++G Sbjct: 299 CRGDEFQCGDGT--CVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNG 345 >gi|65301119 low density lipoprotein receptor-related protein 8 isoform 4 precursor [Homo sapiens] Length = 904 Score = 51.2 bits (121), Expect = 2e-06 Identities = 22/42 (52%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P QFACRSG +C+ L W+CDG C+D+SDEA+CP Sbjct: 256 PAACATASQFACRSG--ECVHLGWRCDGDRDCKDKSDEADCP 295 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 9 AFLLLFLLVLTV---------TEPLR----PELRCNPGQFACRSGTIQCIPLPWQCDGWA 55 A LLL LL+L + +PL P C QF CR+ +CIP W+CD Sbjct: 13 ALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNE--RCIPSVWRCDEDD 70 Query: 56 TCEDESDEANCPEVT 70 C D SDE +CP+ T Sbjct: 71 DCLDHSDEDDCPKKT 85 Score = 39.3 bits (90), Expect = 0.009 Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C + +C + +C+P W+CDG CE +DEA C Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163 Score = 37.7 bits (86), Expect = 0.027 Identities = 18/36 (50%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 30 CNPGQFACRS-GTIQCIPLPWQCDGWATCEDESDEA 64 C P +F C G CIP W CD CED SDEA Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEA 241 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 P+ C F C +G CI W+CDG C D SDE+ Sbjct: 82 PKKTCADSDFTCDNG--HCIHERWKCDGEEECPDGSDES 118 Score = 33.1 bits (74), Expect = 0.68 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 14/64 (21%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGRA 89 C P +F C G C+ + CDG C D SDE C + A PR+ R Sbjct: 167 CAPHEFQC--GNRSCLAAVFVCDGDDDCGDGSDERGCAD-----------PACGPREFRC 213 Query: 90 RGGD 93 GGD Sbjct: 214 -GGD 216 Score = 30.0 bits (66), Expect = 5.7 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHG 78 C +F C GT C+ C+ C D SDEA C + E ++G Sbjct: 299 CRGDEFQCGDGT--CVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNG 345 >gi|28557796 low density lipoprotein receptor class A domain containing 3 [Homo sapiens] Length = 345 Score = 50.8 bits (120), Expect = 3e-06 Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 3/47 (6%) Query: 30 CN-PGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRP 75 CN PG F C +G +CIP WQCDG C D+SDE CP+ + P Sbjct: 29 CNIPGNFMCSNG--RCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGP 73 Score = 39.3 bits (90), Expect = 0.009 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 +C P F C SG I CI ++C+G+ C D SDE NC Sbjct: 70 KCGPTFFPCASG-IHCIIGRFRCNGFEDCPDGSDEENC 106 Score = 36.2 bits (82), Expect = 0.080 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 L C+ ++ C++G CI + CDG C+D SDE +C Sbjct: 111 LLCSTARYHCKNGL--CIDKSFICDGQNNCQDNSDEESC 147 >gi|4504975 low density lipoprotein receptor precursor [Homo sapiens] Length = 860 Score = 50.4 bits (119), Expect = 4e-06 Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT---GEVRPHHGK 79 C G F+C +CIP W+CDG C++ SDE CP T E R H GK Sbjct: 68 CKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGK 120 Score = 44.3 bits (103), Expect = 3e-04 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C+ +F C SG +CI W+CDG C+D+SDE NC T Sbjct: 197 CSAFEFHCLSG--ECIHSSWRCDGGPDCKDKSDEENCAVAT 235 Score = 43.5 bits (101), Expect = 5e-04 Identities = 20/38 (52%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 P L C P F C S T CIP W CD CED SDE Sbjct: 144 PVLTCGPASFQCNSST--CIPQLWACDNDPDCEDGSDE 179 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 4/44 (9%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA--NCPEVT 70 RC +F C+ G +CI W CDG A C+D SDE+ C VT Sbjct: 26 RCERNEFQCQDG--KCISYKWVCDGSAECQDGSDESQETCLSVT 67 Score = 38.5 bits (88), Expect = 0.016 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 P C+ +F C G +CI + CD C D SDEA+CP +T Sbjct: 105 PPKTCSQDEFRCHDG--KCISRQFVCDSDRDCLDGSDEASCPVLT 147 Score = 36.6 bits (83), Expect = 0.061 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 2/41 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C P +F C G CI QCD C+D SDE C VT Sbjct: 236 CRPDEFQCSDGN--CIHGSRQCDREYDCKDMSDEVGCVNVT 274 >gi|11415040 matriptase [Homo sapiens] Length = 855 Score = 50.1 bits (118), Expect = 5e-06 Identities = 21/35 (60%), Positives = 24/35 (68%), Gaps = 2/35 (5%) Query: 32 PGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 PGQF CR+G +CI +CDGWA C D SDE NC Sbjct: 454 PGQFTCRTG--RCIRKELRCDGWADCTDHSDELNC 486 Score = 36.6 bits (83), Expect = 0.061 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEV 69 C F C +G +C+ QC+G C D SDEA+CP+V Sbjct: 525 CPAQTFRCSNG--KCLSKSQQCNGKDDCGDGSDEASCPKV 562 Score = 35.8 bits (81), Expect = 0.10 Identities = 30/102 (29%), Positives = 40/102 (39%), Gaps = 5/102 (4%) Query: 30 CNPG-QFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQ-- 86 C+ G QF C++ C PL W CD C D SDE C R +GK +Q Sbjct: 488 CDAGHQFTCKNKF--CKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQCN 545 Query: 87 GRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWHHYEGTASC 128 G+ GD S + V + +C G +G C Sbjct: 546 GKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPEC 587 >gi|46410931 attractin-like 1 [Homo sapiens] Length = 1379 Score = 49.7 bits (117), Expect = 7e-06 Identities = 41/127 (32%), Positives = 60/127 (47%), Gaps = 27/127 (21%) Query: 115 CPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVL--AQEWDQP 172 C GW H +C RV S ENY +A C L+G+LA+ +T +E+ FVL Q++ Q Sbjct: 748 CGEGWSHIGD--ACLRVNSSRENYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTQQ 805 Query: 173 ERSFGWKDQRKLWVGYQYVITGRNRSLEGRWE--VAFKGSSEVFLPPDPIFASAMSENDN 230 + S W RK+ + Y WE F ++ +LP +P ND+ Sbjct: 806 KVS-PWVGLRKINISY------------WGWEDMSPFTNTTLQWLPGEP--------NDS 844 Query: 231 VFCAQLQ 237 FCA L+ Sbjct: 845 GFCAYLE 851 >gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens] Length = 4544 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/60 (46%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 11 LLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEAN--CPE 68 LLL LL V + C+P QFACR I CI W+CDG C D SDEA CP+ Sbjct: 8 LLLPLLSALVAAAIDAPKTCSPKQFACRD-QITCISKGWRCDGERDCPDGSDEAPEICPQ 66 Score = 47.8 bits (112), Expect = 3e-05 Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Query: 25 RPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 RP C+ +F CR + CIPL W+CDG C D SDE +C VT Sbjct: 1057 RPPGGCHTDEFQCRLDGL-CIPLRWRCDGDTDCMDSSDEKSCEGVT 1101 Score = 47.8 bits (112), Expect = 3e-05 Identities = 21/41 (51%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 PE +C PGQF C +G C + CDG C+D SDEANC Sbjct: 3370 PEFKCRPGQFQCSTGI--CTNPAFICDGDNDCQDNSDEANC 3408 Score = 47.0 bits (110), Expect = 5e-05 Identities = 21/38 (55%), Positives = 24/38 (63%), Gaps = 2/38 (5%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 RC+ QF C+SG CIPL W+CD A C D SDE C Sbjct: 3612 RCDMDQFQCKSG--HCIPLRWRCDADADCMDGSDEEAC 3647 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPEVT 70 PE+ C P QF C S T +CIP W CD C D SDE ANC ++T Sbjct: 3449 PEVTCAPNQFQC-SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMT 3493 Score = 44.3 bits (103), Expect = 3e-04 Identities = 20/41 (48%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C P QF C + T +CIP ++C+G C D DE +CPEVT Sbjct: 3413 CLPSQFKC-TNTNRCIPGIFRCNGQDNCGDGEDERDCPEVT 3452 Score = 42.7 bits (99), Expect = 9e-04 Identities = 19/39 (48%), Positives = 24/39 (61%), Gaps = 2/39 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 P +C PG+FAC + +CI W+CDG C D SDEA Sbjct: 850 PPPQCQPGEFACANS--RCIQERWKCDGDNDCLDNSDEA 886 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/38 (52%), Positives = 24/38 (63%), Gaps = 3/38 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANC 66 C P QF+C SG +CIP+ W CD C D SDE A+C Sbjct: 936 CPPNQFSCASG--RCIPISWTCDLDDDCGDRSDESASC 971 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVR 74 RC FAC SG +CIP+ W CD CE DE +C + E + Sbjct: 2695 RCPLNYFACPSG--RCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQ 2738 Score = 41.6 bits (96), Expect = 0.002 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 27 ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E C P QF C++ +C+P WQCD C D SDE +C Sbjct: 3533 ERTCEPYQFRCKNN--RCVPGRWQCDYDNDCGDNSDEESC 3570 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/39 (53%), Positives = 23/39 (58%), Gaps = 4/39 (10%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE--ANC 66 C+ QF C SG +CIP W CDG C D SDE ANC Sbjct: 1015 CSSTQFKCNSG--RCIPEHWTCDGDNDCGDYSDETHANC 1051 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 2/38 (5%) Query: 30 CNPG-QFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+P +F C+ +CI W CDG CED SDE NC Sbjct: 1104 CDPSVKFGCKDSA-RCISKAWVCDGDNDCEDNSDEENC 1140 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C G+F CR GT CI +C+ + CED SDE NC Sbjct: 2605 CGVGEFRCRDGT--CIGNSSRCNQFVDCEDASDEMNC 2639 Score = 39.3 bits (90), Expect = 0.009 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPE 68 C QF C++ +CIP W+CD C D SDE +CPE Sbjct: 3334 CTASQFVCKND--KCIPFWWKCDTEDDCGDHSDEPPDCPE 3371 Score = 38.9 bits (89), Expect = 0.012 Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+ +F+C +G +CI W+CDG C D SDE +C Sbjct: 3575 CSESEFSCANG--RCIAGRWKCDGDHDCADGSDEKDC 3609 Score = 38.5 bits (88), Expect = 0.016 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C P F+C GT C+P W CDG C D +DE+ Sbjct: 2774 CGPSSFSC-PGTHVCVPERWLCDGDKDCADGADES 2807 Score = 38.1 bits (87), Expect = 0.021 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 2/33 (6%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 QF C +G +CI + W+CD C D SDEA C Sbjct: 981 QFTCNNG--RCININWRCDNDNDCGDNSDEAGC 1011 Score = 38.1 bits (87), Expect = 0.021 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 27 ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE--ANCPEVTGE 72 ++ C +F C+ +CIP W+CDG C D SDE C E T E Sbjct: 3491 QMTCGVDEFRCKDSG-RCIPARWKCDGEDDCGDGSDEPKEECDERTCE 3537 Score = 37.4 bits (85), Expect = 0.036 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 3/36 (8%) Query: 30 CNPGQFACRSGTIQCIPL-PWQCDGWATCEDESDEA 64 C P +F C +G +C+ W+CDG C D+SDEA Sbjct: 2858 CGPSEFRCANG--RCLSSRQWECDGENDCHDQSDEA 2891 Score = 35.4 bits (80), Expect = 0.14 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA-NCPEVTG 71 RC P + C GT C+P+ C+G C D SDE +C E+ G Sbjct: 71 RCQPNEHNCL-GTELCVPMSRLCNGVQDCMDGSDEGPHCRELQG 113 Score = 35.0 bits (79), Expect = 0.18 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C+ QF C++ +CI W CDG C D SDEA Sbjct: 2734 CSEAQFECQNH--RCISKQWLCDGSDDCGDGSDEA 2766 Score = 33.5 bits (75), Expect = 0.52 Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 C +F C + C PL W+CDG C D SDE Sbjct: 3654 CPLDEFQCNNTL--CKPLAWKCDGEDDCGDNSDE 3685 Score = 33.1 bits (74), Expect = 0.68 Identities = 15/36 (41%), Positives = 17/36 (47%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 L C P C + T C+P CDG C D SDE Sbjct: 1143 LACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDE 1178 Score = 32.7 bits (73), Expect = 0.88 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 2/36 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEAN 65 C +F C + +CIP W CDG C + DE+N Sbjct: 895 CPSDRFKCENN--RCIPNRWLCDGDNDCGNSEDESN 928 Score = 32.3 bits (72), Expect = 1.2 Identities = 14/29 (48%), Positives = 15/29 (51%) Query: 41 TIQCIPLPWQCDGWATCEDESDEANCPEV 69 T C W CDG C D SDE +CP V Sbjct: 2663 TSLCYAPSWVCDGANDCGDYSDERDCPGV 2691 Score = 32.3 bits (72), Expect = 1.2 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 27 ELRCNPG-QFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E +CN QF C SG +C+ C+G C D SDE C Sbjct: 2901 EHKCNASSQFLCSSG--RCVAEALLCNGQDDCGDSSDERGC 2939 Score = 30.8 bits (68), Expect = 3.4 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Query: 30 CNPGQ-FACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C P + F C++ + C+ + QCDG C D +DE +C T Sbjct: 3695 CPPNRPFRCKNDRV-CLWIGRQCDGTDNCGDGTDEEDCEPPT 3735 Score = 30.0 bits (66), Expect = 5.7 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA-NCPEVT---GEVRPHHGKEAVDPR 85 C+ +F C++ QCIP + CD C D SDE+ C T E R +G+ + R Sbjct: 2818 CDDREFMCQNR--QCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGR-CLSSR 2874 Query: 86 QGRARGGDPSH 96 Q G + H Sbjct: 2875 QWECDGENDCH 2885 Score = 29.6 bits (65), Expect = 7.5 Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 2/30 (6%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDE 63 +F C +G +CI CDG C+D+SDE Sbjct: 2529 EFECANG--ECINFSLTCDGVPHCKDKSDE 2556 >gi|29244926 corin [Homo sapiens] Length = 1042 Score = 48.1 bits (113), Expect = 2e-05 Identities = 20/37 (54%), Positives = 25/37 (67%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+P F CRSG QC+ +CDG A C+D+SDE NC Sbjct: 580 CSPSHFKCRSG--QCVLASRRCDGQADCDDDSDEENC 614 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 5/43 (11%) Query: 27 ELRCN---PGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E+ C+ G CR+G QCIP +QCDG C+D SDE NC Sbjct: 374 EVNCSCHSQGLVECRNG--QCIPSTFQCDGDEDCKDGSDEENC 414 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 27 ELRCNPGQ-FACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGK 79 +L C G+ F C SG CIP QC+G+ C+D SDEA+C H GK Sbjct: 266 QLLCGRGENFLCASGI--CIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGK 317 Score = 38.9 bits (89), Expect = 0.012 Identities = 18/37 (48%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 CNP R G +CI + W CDG C D+SDE NC Sbjct: 342 CNPTT-EHRCGDGRCIAMEWVCDGDHDCVDKSDEVNC 377 Score = 34.3 bits (77), Expect = 0.30 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+ F C +G +C+ CDG+ C D SDE NC Sbjct: 306 CSENLFHCHTG--KCLNYSLVCDGYDDCGDLSDEQNC 340 Score = 29.3 bits (64), Expect = 9.8 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C + C + C+ CDG A C D SDE +C Sbjct: 655 CQDDELECANHA--CVSRDLWCDGEADCSDSSDEWDC 689 >gi|65301164 very low density lipoprotein receptor isoform b [Homo sapiens] Length = 845 Score = 48.1 bits (113), Expect = 2e-05 Identities = 21/42 (50%), Positives = 26/42 (61%), Gaps = 2/42 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 +C P QF C +G +CI L W+CDG C D SDE NC + T Sbjct: 32 KCEPSQFQCTNG--RCITLLWKCDGDEDCVDGSDEKNCVKKT 71 Score = 45.1 bits (105), Expect = 2e-04 Identities = 16/41 (39%), Positives = 24/41 (58%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C + +C + + QCIP+ W+CDG C+ DE NC +T Sbjct: 113 CRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNIT 153 Score = 44.3 bits (103), Expect = 3e-04 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 +C + C SG +CI W+CDG C+D SDE NCP T Sbjct: 238 KCPASEIQCGSG--ECIHKKWRCDGDPDCKDGSDEVNCPSRT 277 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/35 (48%), Positives = 21/35 (60%), Gaps = 2/35 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C F C +G QC+P W+CDG CED SDE+ Sbjct: 72 CAESDFVCNNG--QCVPSRWKCDGDPDCEDGSDES 104 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEV 69 P C P QF C G+ CI QC+G C D SDE NC V Sbjct: 274 PSRTCRPDQFECEDGS--CIHGSRQCNGIRDCVDGSDEVNCKNV 315 Score = 38.5 bits (88), Expect = 0.016 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C +F C T CIP+ W CD A C D+SDE+ Sbjct: 193 CGAHEFQC--STSSCIPISWVCDDDADCSDQSDES 225 Score = 38.1 bits (87), Expect = 0.021 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 + C+P +F C SG +CI + C+G C D SDE +C T Sbjct: 152 ITCSPDEFTCSSG--RCISRNFVCNGQDDCSDGSDELDCAPPT 192 Score = 31.6 bits (70), Expect = 2.0 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 32 PGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 PG+F CRSG +CI + C+ C D SDE Sbjct: 321 PGKFKCRSG--ECIDISKVCNQEQDCRDWSDE 350 >gi|65301167 very low density lipoprotein receptor isoform a [Homo sapiens] Length = 873 Score = 48.1 bits (113), Expect = 2e-05 Identities = 21/42 (50%), Positives = 26/42 (61%), Gaps = 2/42 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 +C P QF C +G +CI L W+CDG C D SDE NC + T Sbjct: 32 KCEPSQFQCTNG--RCITLLWKCDGDEDCVDGSDEKNCVKKT 71 Score = 45.1 bits (105), Expect = 2e-04 Identities = 16/41 (39%), Positives = 24/41 (58%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C + +C + + QCIP+ W+CDG C+ DE NC +T Sbjct: 113 CRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNIT 153 Score = 44.3 bits (103), Expect = 3e-04 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 +C + C SG +CI W+CDG C+D SDE NCP T Sbjct: 238 KCPASEIQCGSG--ECIHKKWRCDGDPDCKDGSDEVNCPSRT 277 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/35 (48%), Positives = 21/35 (60%), Gaps = 2/35 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C F C +G QC+P W+CDG CED SDE+ Sbjct: 72 CAESDFVCNNG--QCVPSRWKCDGDPDCEDGSDES 104 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEV 69 P C P QF C G+ CI QC+G C D SDE NC V Sbjct: 274 PSRTCRPDQFECEDGS--CIHGSRQCNGIRDCVDGSDEVNCKNV 315 Score = 38.5 bits (88), Expect = 0.016 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 C +F C T CIP+ W CD A C D+SDE+ Sbjct: 193 CGAHEFQC--STSSCIPISWVCDDDADCSDQSDES 225 Score = 38.1 bits (87), Expect = 0.021 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 + C+P +F C SG +CI + C+G C D SDE +C T Sbjct: 152 ITCSPDEFTCSSG--RCISRNFVCNGQDDCSDGSDELDCAPPT 192 Score = 31.6 bits (70), Expect = 2.0 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 32 PGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 PG+F CRSG +CI + C+ C D SDE Sbjct: 321 PGKFKCRSG--ECIDISKVCNQEQDCRDWSDE 350 >gi|157384998 low density lipoprotein receptor-related protein 4 [Homo sapiens] Length = 1905 Score = 47.8 bits (112), Expect = 3e-05 Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C G+F C SG CI W+CDG A C+D+SDE NC Sbjct: 231 CRSGEFMCDSGL--CINAGWRCDGDADCDDQSDERNC 265 Score = 45.8 bits (107), Expect = 1e-04 Identities = 22/42 (52%), Positives = 25/42 (59%), Gaps = 3/42 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTG 71 C QF C SG +C+ L W+CDG C D SDE NC E TG Sbjct: 270 CTAEQFRCHSG--RCVRLSWRCDGEDDCADNSDEENC-ENTG 308 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 14/112 (12%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT-------GEVRPHHGKEA 81 +C+ +F C G+ CI W CDG C+D SDE NCP E + +G+ Sbjct: 147 KCSDKEFRCSDGS--CIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCI 204 Query: 82 VD--PRQGRARGGDPSHFHAVNVAQPVRFSSFL---GKCPTGWHHYEGTASC 128 +D G GD S + QP R F+ G C +G A C Sbjct: 205 LDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADC 256 Score = 44.3 bits (103), Expect = 3e-04 Identities = 19/38 (50%), Positives = 24/38 (63%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C+P F C +G +CI W CDG CED+SDE +CP Sbjct: 71 CSPLDFHCDNG--KCIRRSWVCDGDNDCEDDSDEQDCP 106 Score = 43.5 bits (101), Expect = 5e-04 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%) Query: 26 PELRCNPGQFACRS---GTIQCIPLPWQCDGWATCEDESDEANC 66 PE C F C G CIP WQCDG C D SDE C Sbjct: 23 PECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGC 66 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 P C +F C++G CI W CDG C D SDE Sbjct: 106 PPRECEEDEFPCQNG--YCIRSLWHCDGDNDCGDNSDE 141 Score = 32.0 bits (71), Expect = 1.5 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA---NCPEVTGEVRPHHGKEAVDPR 85 +C QF C +G +CI C+G C D SDE+ NC TGE + + Sbjct: 311 QCALDQFLCWNG--RCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQK 368 Query: 86 QGRARGGDPSHFHA-------VNVAQPVRFSSFLGKCPTGWHHYEGTASCY 129 RG H + Q V + G C G + EG C+ Sbjct: 369 CQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCW 419 >gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens] Length = 4655 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 6 DSGAFLLLFLLVLTVTEPLRPEL--RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 D G + L+L + L P C+ F C SG CIP W+CDG C D++DE Sbjct: 2 DRGPAAVACTLLLALVACLAPASGQECDSAHFRCGSG--HCIPADWRCDGTKDCSDDADE 59 Query: 64 ANCPEVT 70 C VT Sbjct: 60 IGCAVVT 66 Score = 47.4 bits (111), Expect = 3e-05 Identities = 22/41 (53%), Positives = 25/41 (60%), Gaps = 3/41 (7%) Query: 27 ELRCNP-GQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E C+P G F C++ CIPL WQCDG C D SDE NC Sbjct: 3716 ERTCHPVGDFRCKNH--HCIPLRWQCDGQNDCGDNSDEENC 3754 Score = 43.5 bits (101), Expect = 5e-04 Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 L C QF C SG +CI + +CDG C D SDEA CP Sbjct: 1185 LNCTASQFKCASGD-KCIGVTNRCDGVFDCSDNSDEAGCP 1223 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C+P F C SG C+ +CDG A C D SDEA+CP Sbjct: 3798 CHPEYFQCTSG--HCVHSELKCDGSADCLDASDEADCP 3833 Score = 42.0 bits (97), Expect = 0.001 Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C+ F C G +CIP W+CD C D SDE NCP Sbjct: 1067 CSSSAFTCGHG--ECIPAHWRCDKRNDCVDGSDEHNCP 1102 Score = 42.0 bits (97), Expect = 0.001 Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 C PGQF C +G +CIP W+CD C D SDE Sbjct: 3635 CRPGQFRCANG--RCIPQAWKCDVDNDCGDHSDE 3666 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 2/40 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPE 68 C+ QF C + +CIP+ W+CDG C D SDE A CP+ Sbjct: 3512 CSSTQFLCANNE-KCIPIWWKCDGQKDCSDGSDELALCPQ 3550 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGR 88 C QF C SG +CI W CDG C+D DE C +V +E P GR Sbjct: 222 CGGYQFTCPSG--RCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGR 278 Score = 38.9 bits (89), Expect = 0.012 Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEAN 65 P RP C+ +F C+ I CIP W+CDG C SDE N Sbjct: 1223 PTRPPGMCHSDEFQCQEDGI-CIPNFWECDGHPDCLYGSDEHN 1264 Score = 37.4 bits (85), Expect = 0.036 Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+P F C +G +C+ ++CD + C D SDEA C Sbjct: 2741 CSPTAFTCANG--RCVQYSYRCDYYNDCGDGSDEAGC 2775 Score = 37.4 bits (85), Expect = 0.036 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 3/38 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANC 66 C+ +F C SG +CIP W CD C D SDE A+C Sbjct: 2864 CSSSEFQCASG--RCIPQHWYCDQETDCFDASDEPASC 2899 Score = 37.4 bits (85), Expect = 0.036 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRP 75 C+ ++ C + +CIP WQCD + CED SDE + + RP Sbjct: 3594 CDSNEWQCANK--RCIPESWQCDTFNDCEDNSDEDSSHCASRTCRP 3637 Score = 37.4 bits (85), Expect = 0.036 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C +F C + QCIP W CD + C D SDE +C Sbjct: 3759 CTESEFRCVNQ--QCIPSRWICDHYNDCGDNSDERDC 3793 Score = 37.0 bits (84), Expect = 0.047 Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPEVT 70 C G F C+S QCIP W CD C+D SDE +C + T Sbjct: 67 CQQGYFKCQSEG-QCIPNSWVCDQDQDCDDGSDERQDCSQST 107 Score = 36.6 bits (83), Expect = 0.061 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C P QF C + +CI L + CDG C D SDE C Sbjct: 1149 CQPSQFNCPNH--RCIDLSFVCDGDKDCVDGSDEVGC 1183 Score = 35.8 bits (81), Expect = 0.10 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGE 72 C+ Q C +G QCIP ++CD C D +DE +C T E Sbjct: 108 CSSHQITCSNG--QCIPSEYRCDHVRDCPDGADENDCQYPTCE 148 Score = 35.8 bits (81), Expect = 0.10 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P +C F C++G +C+P + CDG C D SDE C Sbjct: 1022 PTEQCGLFSFPCKNG--RCVPNYYLCDGVDDCHDNSDEQLC 1060 Score = 35.0 bits (79), Expect = 0.18 Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 27 ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 E C +F C G +CIP W CDG C D SDE Sbjct: 2903 ERTCLADEFKCDGG--RCIPSEWICDGDNDCGDMSDE 2937 Score = 33.9 bits (76), Expect = 0.40 Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 RC F C +G +CI W+CD C D SDE Sbjct: 2699 RCGASSFTCSNG--RCISEEWKCDNDNDCGDGSDE 2731 Score = 33.9 bits (76), Expect = 0.40 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 P+ C G C + I CIP + CDG C D SDE Sbjct: 2818 PDRTCQSGYTKCHNSNI-CIPRVYLCDGDNDCGDNSDE 2854 Score = 33.9 bits (76), Expect = 0.40 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 4/45 (8%) Query: 30 CNPGQFAC---RSGTIQCIPLPWQCDGWATCEDESDE-ANCPEVT 70 C+ +F C R +CIP W CDG C D DE NC T Sbjct: 2948 CSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRT 2992 Score = 33.5 bits (75), Expect = 0.52 Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C F C +G CI W CD C D SDE +CP Sbjct: 1271 CPSSYFHCDNGN--CIHRAWLCDRDNDCGDMSDEKDCP 1306 Score = 33.1 bits (74), Expect = 0.68 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C +F+C +G +CIP + CD C+D SDE C Sbjct: 183 CLHNEFSCGNG--ECIPRAYVCDHDNDCQDGSDEHAC 217 Score = 33.1 bits (74), Expect = 0.68 Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P C Q+ C + QCI W CD C D SDE NC Sbjct: 1102 PTHAPASCLDTQYTCDNH--QCISKNWVCDTDNDCGDGSDEKNC 1143 Score = 33.1 bits (74), Expect = 0.68 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 PE C P +F C +G +CI + C+ C D SDE C Sbjct: 3071 PEPTCPPHEFKCDNG--RCIEMMKLCNHLDDCLDNSDEKGC 3109 Score = 33.1 bits (74), Expect = 0.68 Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 C F C++ CIP W+CDG C D SDE Sbjct: 3842 CQATMFECKNHV--CIPPYWKCDGDDDCGDGSDE 3873 Score = 32.7 bits (73), Expect = 0.88 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+ +F C G CIP ++CD C D SDE C Sbjct: 2993 CSENEFTCGYGL--CIPKIFRCDRHNDCGDYSDERGC 3027 Score = 32.3 bits (72), Expect = 1.2 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 +F+C++ +CIP C+G C D SDE C E T Sbjct: 3683 EFSCKTN-YRCIPKWAVCNGVDDCRDNSDEQGCEERT 3718 Score = 32.0 bits (71), Expect = 1.5 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDE--SDEANCPEVT 70 +F C + +CIP + C+G C D SDE NCP+ T Sbjct: 2785 EFMCNNR--RCIPREFICNGVDNCHDNNTSDEKNCPDRT 2821 Score = 31.2 bits (69), Expect = 2.6 Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEV 69 Q C +G C +CD C D SDE NC E+ Sbjct: 149 QLTCDNGA--CYNTSQKCDWKVDCRDSSDEINCTEI 182 Score = 29.6 bits (65), Expect = 7.5 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 8/54 (14%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE----ANCPEVTGEVRPHHGK 79 C QF C++G +CI + CD C D SDE + PE T PH K Sbjct: 3032 CQQNQFTCQNG--RCISKTFVCDEDNDCGDGSDELMHLCHTPEPT--CPPHEFK 3081 >gi|134031945 SCO-spondin [Homo sapiens] Length = 5147 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/76 (38%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 19 TVTEPLR---PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRP 75 T + PL P C P +F C SG +C P W+CD C D SDE C G P Sbjct: 1551 TASSPLASASPAPPCGPFEFRCGSG--ECTPRGWRCDQEEDCADGSDERGC---GGPCAP 1605 Query: 76 HH-----GKEAVDPRQ 86 HH G V P Q Sbjct: 1606 HHAPCARGPHCVSPEQ 1621 Score = 36.2 bits (82), Expect = 0.080 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P ++C PGQ C + C+ CDG C D SDE +C Sbjct: 2387 PPVQCGPGQTPCE--VLGCVEQAQVCDGREDCLDGSDERHC 2425 Score = 35.0 bits (79), Expect = 0.18 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P C G AC G +C+P CDG C D +DE +C Sbjct: 1448 PSYPCPQGLLACADG--RCLPPALLCDGHPDCLDAADEESC 1486 Score = 35.0 bits (79), Expect = 0.18 Identities = 23/56 (41%), Positives = 27/56 (48%), Gaps = 6/56 (10%) Query: 112 LGKCPTGWHHYEGTA-SCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLA 166 LG CP GW EGT SC L GEN QT Q + A + ++RF LA Sbjct: 2004 LGSCPQGWVLVEGTGESCCHCALPGEN-----QTVQPMATPAAAPAPSPQIRFPLA 2054 Score = 34.7 bits (78), Expect = 0.23 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C+P Q +C SG +C+ +CD C+D SDE C Sbjct: 2464 CSPSQLSCGSG--ECLSAERRCDLRPDCQDGSDEDGC 2498 Score = 34.3 bits (77), Expect = 0.30 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C GQ C SG C+PL CD C D +DE + P Sbjct: 1416 CGEGQMTCSSG--HCLPLALLCDRQDDCGDGTDEPSYP 1451 Score = 34.3 bits (77), Expect = 0.30 Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 16/63 (25%) Query: 23 PLRPELR-CNPGQ----------FACRSGTIQCIPLPWQCDGWATCEDESDEANC---PE 68 PL+ EL C PG C SG +C+ CDG CED SDE C PE Sbjct: 2216 PLQVELLGCEPGSPPAPLCPGVGLRCASG--ECVLRGGPCDGVLDCEDGSDEEGCVLLPE 2273 Query: 69 VTG 71 TG Sbjct: 2274 GTG 2276 Score = 33.1 bits (74), Expect = 0.68 Identities = 14/37 (37%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C G+ C+ C+P W CD C D SDE C Sbjct: 1376 CAEGEALCQENG-HCVPHGWLCDNQDDCGDGSDEEGC 1411 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 46.6 bits (109), Expect = 6e-05 Identities = 20/42 (47%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P C P +F C +G C W+CDG CED +DEANCP Sbjct: 321 PPPPCEPNEFPCGNG--HCALKLWRCDGDFDCEDRTDEANCP 360 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/49 (46%), Positives = 28/49 (57%), Gaps = 6/49 (12%) Query: 22 EPLRP----ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 +PL P L C P + ACR+G CIP + CDG CED SDE +C Sbjct: 273 QPLLPGSVRPLPCGPQEAACRNG--HCIPRDYLCDGQEDCEDGSDELDC 319 Score = 43.1 bits (100), Expect = 7e-04 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 25 RPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 RPE C P QF C S T CIP + CD + C D SDE C Sbjct: 363 RPEEVCGPTQFRCVS-TNMCIPASFHCDEESDCPDRSDEFGC 403 Score = 40.0 bits (92), Expect = 0.006 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRP 75 C +FAC S +C+ L ++CD C D SDE NC E + P Sbjct: 199 CTEAEFACHSYN-ECVALEYRCDRRPDCRDMSDELNCEEPVLGISP 243 >gi|61744467 low density lipoprotein receptor-related protein 8 isoform 3 precursor [Homo sapiens] Length = 700 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 9 AFLLLFLLVLTV---------TEPLR----PELRCNPGQFACRSGTIQCIPLPWQCDGWA 55 A LLL LL+L + +PL P C QF CR+ +CIP W+CD Sbjct: 13 ALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNE--RCIPSVWRCDEDD 70 Query: 56 TCEDESDEANCPEVT 70 C D SDE +CP+ T Sbjct: 71 DCLDHSDEDDCPKKT 85 Score = 40.8 bits (94), Expect = 0.003 Identities = 16/45 (35%), Positives = 23/45 (51%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVR 74 C + +C + +C+P W+CDG CE +DEA C G R Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATSLGTCR 171 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 P+ C F C +G CI W+CDG C D SDE+ Sbjct: 82 PKKTCADSDFTCDNG--HCIHERWKCDGEEECPDGSDES 118 Score = 30.0 bits (66), Expect = 5.7 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHG 78 C +F C GT C+ C+ C D SDEA C + E ++G Sbjct: 170 CRGDEFQCGDGT--CVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNG 216 >gi|66082554 low density lipoprotein receptor-related protein 8 isoform 2 precursor [Homo sapiens] Length = 793 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 9 AFLLLFLLVLTV---------TEPLR----PELRCNPGQFACRSGTIQCIPLPWQCDGWA 55 A LLL LL+L + +PL P C QF CR+ +CIP W+CD Sbjct: 13 ALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNE--RCIPSVWRCDEDD 70 Query: 56 TCEDESDEANCPEVT 70 C D SDE +CP+ T Sbjct: 71 DCLDHSDEDDCPKKT 85 Score = 40.0 bits (92), Expect = 0.006 Identities = 16/49 (32%), Positives = 25/49 (51%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHG 78 C + +C + +C+P W+CDG CE +DEA C E ++G Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATWLNECLHNNG 175 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 P+ C F C +G CI W+CDG C D SDE+ Sbjct: 82 PKKTCADSDFTCDNG--HCIHERWKCDGEEECPDGSDES 118 >gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1542 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P++P C QF+C T+QC+PL +CDG C D SDE +CP Sbjct: 1332 PVQPS-PCEADQFSCIY-TLQCVPLSGKCDGHEDCIDGSDEMDCP 1374 Score = 34.7 bits (78), Expect = 0.23 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P C +F CRS CI +CD C D+SDEA+C Sbjct: 411 PPHNCTDNEFICRSDG-HCIEKMQKCDFKYDCPDKSDEASC 450 Score = 34.7 bits (78), Expect = 0.23 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCED-ESDEANCPE 68 C+ G C S CIP +CDG+A C D + DE++C + Sbjct: 1421 CSNGALVCASSN-SCIPAHQRCDGFADCMDFQLDESSCSD 1459 >gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1817 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P++P C QF+C T+QC+PL +CDG C D SDE +CP Sbjct: 1607 PVQPS-PCEADQFSCIY-TLQCVPLSGKCDGHEDCIDGSDEMDCP 1649 Score = 34.7 bits (78), Expect = 0.23 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P C +F CRS CI +CD C D+SDEA+C Sbjct: 686 PPHNCTDNEFICRSDG-HCIEKMQKCDFKYDCPDKSDEASC 725 Score = 34.7 bits (78), Expect = 0.23 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCED-ESDEANCPE 68 C+ G C S CIP +CDG+A C D + DE++C + Sbjct: 1696 CSNGALVCASSN-SCIPAHQRCDGFADCMDFQLDESSCSD 1734 Score = 33.1 bits (74), Expect = 0.68 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 C+ +F C SG QCI CD C DESDE Sbjct: 74 CSADEFPCTSG--QCIAKESVCDSRQDCSDESDE 105 >gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo sapiens] Length = 1817 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 P++P C QF+C T+QC+PL +CDG C D SDE +CP Sbjct: 1607 PVQPS-PCEADQFSCIY-TLQCVPLSGKCDGHEDCIDGSDEMDCP 1649 Score = 34.7 bits (78), Expect = 0.23 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P C +F CRS CI +CD C D+SDEA+C Sbjct: 686 PPHNCTDNEFICRSDG-HCIEKMQKCDFKYDCPDKSDEASC 725 Score = 34.7 bits (78), Expect = 0.23 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCED-ESDEANCPE 68 C+ G C S CIP +CDG+A C D + DE++C + Sbjct: 1696 CSNGALVCASSN-SCIPAHQRCDGFADCMDFQLDESSCSD 1734 Score = 33.1 bits (74), Expect = 0.68 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 C+ +F C SG QCI CD C DESDE Sbjct: 74 CSADEFPCTSG--QCIAKESVCDSRQDCSDESDE 105 >gi|93102379 low density lipoprotein-related protein 1B precursor [Homo sapiens] Length = 4599 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Query: 11 LLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA--NCPE 68 LL VLTV R + C+PG+F C + C+ W CDG C D+SDE+ CPE Sbjct: 14 LLPIARVLTVGAD-RDQQLCDPGEFLCHDH-VTCVSQSWLCDGDPDCPDDSDESLDTCPE 71 Score = 44.3 bits (103), Expect = 3e-04 Identities = 21/45 (46%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 PE C+P F C++ T CI W CD C D SDEANC + T Sbjct: 3432 PENSCSPDYFQCKT-TKHCISKLWVCDEDPDCADASDEANCDKKT 3475 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/41 (51%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 26 PELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 PE RC PG+F C GT C + CDG C D SDE NC Sbjct: 3353 PEFRCQPGRFQC--GTGLCALPAFICDGENDCGDNSDELNC 3391 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C P +F C++ CIP W+CD C D SDE NC T Sbjct: 3476 CGPHEFQCKNNN--CIPDHWRCDSQNDCSDNSDEENCKPQT 3514 Score = 43.1 bits (100), Expect = 7e-04 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 27 ELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E C+ QF C +G QCIP W+CDG C+ DE +C Sbjct: 3550 ETSCSKDQFRCSNG--QCIPAKWKCDGHEDCKYGEDEKSC 3587 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/37 (48%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C QF C++ CIP+ W CDG C D SDE NC Sbjct: 3632 CKEDQFRCKNKA-HCIPIRWLCDGIHDCVDGSDEENC 3667 Score = 41.6 bits (96), Expect = 0.002 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPE 68 C GQF C +CIP+ +C+G C DE DE +CPE Sbjct: 3396 CLSGQFKCTKNQ-KCIPVNLRCNGQDDCGDEEDERDCPE 3433 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 22 EPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 E + CN +F C C+P W+CDG CED SDE C Sbjct: 1045 EEIHSPAGCNGNEFQCHPDG-NCVPDLWRCDGEKDCEDGSDEKGC 1088 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 P++ + +C F+C SG +CI W CDG CED DE +C Sbjct: 2675 PVQNKHKCEENYFSCPSG--RCILNTWICDGQKDCEDGRDEFHC 2716 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA--NC 66 C QF C SG +CIP W CDG C D SDEA NC Sbjct: 1006 CFDNQFRCSSG--RCIPGHWACDGDNDCGDFSDEAQINC 1042 Score = 38.9 bits (89), Expect = 0.012 Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA-NCPE 68 C QF C+ T +CIP W+CD C D SDE +CPE Sbjct: 3317 CTASQFRCK--TDKCIPFWWKCDTVDDCGDGSDEPDDCPE 3354 Score = 38.1 bits (87), Expect = 0.021 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%) Query: 23 PLRPELR-----CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 PL P+ + CN F C++G +CIP CD C D SDE NC Sbjct: 2879 PLNPKCKSAEQSCNSSFFMCKNG--RCIPSGGLCDNKDDCGDGSDERNC 2925 Score = 37.4 bits (85), Expect = 0.036 Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 3/38 (7%) Query: 30 CNP-GQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C P QF C+SG +CI W CD C D SDE C Sbjct: 967 CEPLTQFVCKSG--RCISSKWHCDSDDDCGDGSDEVGC 1002 Score = 37.4 bits (85), Expect = 0.036 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 +F+C S T +CI W CDG CED+SDE +C Sbjct: 1100 KFSCWS-TGRCINKAWVCDGDIDCEDQSDEDDC 1131 Score = 36.6 bits (83), Expect = 0.061 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 3/44 (6%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPEVTGE 72 C QF+C +G +CIP W CD C D++DE A+C T E Sbjct: 927 CQVDQFSCGNG--RCIPRAWLCDREDDCGDQTDEMASCEFPTCE 968 Score = 35.8 bits (81), Expect = 0.10 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 + C F+C+ G+ C+P W CDG C D SDE Sbjct: 2759 ITCAADMFSCQ-GSRACVPRHWLCDGERDCPDGSDE 2793 Score = 35.4 bits (80), Expect = 0.14 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE--ANC 66 C G+F C++ CI W+CDG C D SDE NC Sbjct: 845 CKAGEFRCKNR--HCIQARWKCDGDDDCLDGSDEDSVNC 881 Score = 35.4 bits (80), Expect = 0.14 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C +FAC + +CIP+ QCD C D SDE C Sbjct: 3762 CKKDEFACSNK--KCIPMDLQCDRLDDCGDGSDEQGC 3796 Score = 35.0 bits (79), Expect = 0.18 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEAN 65 C QF C++ +CIP W CDG C DE+N Sbjct: 886 CPDDQFKCQNN--RCIPKRWLCDGANDCGSNEDESN 919 Score = 33.9 bits (76), Expect = 0.40 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEA 64 +C +F+C G + WQCDG C D SDEA Sbjct: 2844 QCGTEEFSCADGRC-LLNTQWQCDGDFDCPDHSDEA 2878 Score = 33.5 bits (75), Expect = 0.52 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C +F C GT CIP +C+ C D SDE NC Sbjct: 2591 CATVEFRCADGT--CIPRSARCNQNIDCADASDEKNC 2625 Score = 32.7 bits (73), Expect = 0.88 Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 33 GQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 G C S ++ C+ W CDG C D SDE CP Sbjct: 2642 GFIRCNSTSL-CVLPTWICDGSNDCGDYSDELKCP 2675 Score = 32.3 bits (72), Expect = 1.2 Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C F C +G C+ + CDG C D SDE NC Sbjct: 3515 CTLKDFLCANG--DCVSSRFWCDGDFDCADGSDERNC 3549 Score = 32.0 bits (71), Expect = 1.5 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEAN--CPEVT--GEVRPHHGKEAVDPR 85 C+ QFAC + +CI W CDG C D DE++ C +T ++ G A PR Sbjct: 2720 CSWNQFACSAQ--KCISKHWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPR 2777 Score = 30.8 bits (68), Expect = 3.4 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 21 TEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE-ANCPEV 69 T P E++C AC GT +C+ L C+G C D DE +C E+ Sbjct: 68 TCPEEVEIKCPLNHIACL-GTNKCVHLSQLCNGVLDCPDGYDEGVHCQEL 116 Score = 30.0 bits (66), Expect = 5.7 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 30 CNP-GQFACRSGTIQCIPLPWQCDGWATCEDESDE 63 CN +F C +G +CI CDG C+D+SDE Sbjct: 2510 CNAYSEFECGNG--ECIDYQLTCDGIPHCKDKSDE 2542 Score = 30.0 bits (66), Expect = 5.7 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 82 VDPRQGRARGGDPSHFHAVNVAQPVRFSSFL-GKCPTGWHHYEGTASCYRVYLSGEN 137 +DP + R GG PS F + A P+ +S L G G +Y ++Y+ G+N Sbjct: 4516 IDPTKARYIGGGPSAFKLPHTAPPIYLNSDLKGPLTAGPTNYSNPVYA-KLYMDGQN 4571 Score = 29.6 bits (65), Expect = 7.5 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%) Query: 22 EPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 EP P C+ ++ C S CI +C+G C D SDE +C Sbjct: 3588 EPASPT--CSSREYICASDG--CISASLKCNGEYDCADGSDEMDC 3628 Score = 29.3 bits (64), Expect = 9.8 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 5/36 (13%) Query: 36 ACRSG-----TIQCIPLPWQCDGWATCEDESDEANC 66 +CR G +CIP CDG C D SDE +C Sbjct: 2551 SCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 2586 >gi|167555125 low density lipoprotein receptor-related protein 3 [Homo sapiens] Length = 770 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 26 PELRCNPGQFACRSG-TIQCIPLPWQCDGWATCEDESDEANCPEVT--GEVRPHHGKEAV 82 P C G F C + +C+P+ +CDG C D SDEA CP++ + +G A Sbjct: 208 PGSLCPGGTFPCSGARSTRCLPVERRCDGLQDCGDGSDEAGCPDLACGRRLGSFYGSFAS 267 Query: 83 DPRQGRARGGDPSHFH 98 G ARG PS H Sbjct: 268 PDLFGAARG--PSDLH 281 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C PG F C GT CI W+CDG C+D SDE C Sbjct: 455 CQPGTFHC--GTNLCIFETWRCDGQEDCQDGSDEHGC 489 Score = 42.0 bits (97), Expect = 0.001 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGE 72 C +F C +G +C+P PWQC+ C D SDE NC E Sbjct: 166 CQADEFRCDNG--KCLPGPWQCNTVDECGDGSDEGNCSAPASE 206 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C P Q+ C G+ C +C+ +C D +DE NC Sbjct: 416 CPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNC 452 Score = 32.3 bits (72), Expect = 1.2 Identities = 13/35 (37%), Positives = 15/35 (42%) Query: 44 CIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHG 78 C P +CDGW C DE CP + P G Sbjct: 391 CFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEG 425 >gi|4507157 sortilin-related receptor containing LDLR class A repeats preproprotein [Homo sapiens] Length = 2214 Score = 43.9 bits (102), Expect = 4e-04 Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVT 70 C+ F C++G CI L W+CDG C D SDEANC T Sbjct: 1325 CDEFGFQCQNGV--CISLIWKCDGMDDCGDYSDEANCENPT 1363 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 C P + C SGT C+ W CDG+ C D SDE CP Sbjct: 1419 CLPNYYRCSSGT--CVMDTWVCDGYRDCADGSDEEACP 1454 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 4/51 (7%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDE--ANCPEVTGEVRPHHG 78 C F CR+G CIP W CDG C+D SDE NC + R +G Sbjct: 1199 CEASNFQCRNG--HCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNG 1247 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEV 69 +C ++ C SG CI W CDG C D SDEANC + Sbjct: 1157 QCRSDEYNCSSG--MCIRSSWVCDGDNDCRDWSDEANCTAI 1195 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 23 PLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPE 68 P L C +F C G CI L +CDG+ C DESDE C + Sbjct: 1507 PTHSTLTCMSREFQCEDGEA-CIVLSERCDGFLDCSDESDEKACSD 1551 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 4/45 (8%) Query: 22 EPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 +P+ E +CN F C +GT CIP CDG C D SDE +C Sbjct: 1231 DPVNCEKKCNG--FRCPNGT--CIPSSKHCDGLRDCSDGSDEQHC 1271 Score = 38.9 bits (89), Expect = 0.012 Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 29 RCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 RC+ +F C CIP +CDG C+D DEANCP Sbjct: 1470 RCDRFEFECHQPKT-CIPNWKRCDGHQDCQDGRDEANCP 1507 Score = 36.6 bits (83), Expect = 0.061 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 24 LRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCP 67 ++ E C Q+ C +G CI W CD C D SDE NCP Sbjct: 1072 VKEENTCLRNQYRCSNGN--CINSIWWCDFDNDCGDMSDERNCP 1113 Score = 35.8 bits (81), Expect = 0.10 Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 2/33 (6%) Query: 34 QFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 QF C +G CIP W+CD C D SDE +C Sbjct: 1373 QFRCENG--HCIPNRWKCDRENDCGDWSDEKDC 1403 Score = 35.4 bits (80), Expect = 0.14 Identities = 18/34 (52%), Positives = 23/34 (67%), Gaps = 3/34 (8%) Query: 34 QFACR-SGTIQCIPLPWQCDGWATCEDESDEANC 66 QF C+ SGT CIPL ++CD C D SDE++C Sbjct: 1122 QFRCQESGT--CIPLSYKCDLEDDCGDNSDESHC 1153 >gi|7706111 8D6 antigen [Homo sapiens] Length = 282 Score = 43.9 bits (102), Expect = 4e-04 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 28 LRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDP 84 L C G+ C CIPL W+CDG C D SDE C T E+ P + P Sbjct: 130 LACLAGELRCTLSD-DCIPLTWRCDGHPDCPDSSDELGCG--TNEILPEGDATTMGP 183 Score = 42.4 bits (98), Expect = 0.001 Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 30 CNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANC 66 C P +F CR+ + C+PL W+CD C D SDE C Sbjct: 54 CPPTKFQCRTSGL-CVPLTWRCDRDLDCSDGSDEEEC 89 >gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo sapiens] Length = 1324 Score = 43.1 bits (100), Expect = 7e-04 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 115 CPTGWHHYEGTASCYRVY-----LSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEW 169 C W G ASC++V+ L + +A C+ LA+F+ +E FV Sbjct: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVN---- 719 Query: 170 DQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWE 204 + F W ++R+ W+G+ RN G WE Sbjct: 720 ELLHSKFNWTEERQFWIGF----NKRNPLNAGSWE 750 Score = 36.6 bits (83), Expect = 0.061 Identities = 32/170 (18%), Positives = 72/170 (42%), Gaps = 29/170 (17%) Query: 115 CPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPER 174 C GW+ Y +CY++ + + +A ++CQ N +L ++ E+ F++ Sbjct: 378 CEPGWNPYN--RNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVT-------- 427 Query: 175 SFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCA 234 G ++ + W+G + V+F+ S++ IF + + ++F Sbjct: 428 LLGDENASETWIGLS----------SNKIPVSFEWSND----SSVIFTNWHTLEPHIFPN 473 Query: 235 QLQ-CFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGF 283 + Q C H W ++C E+ ++CK++ + ++ EG+ Sbjct: 474 RSQLCVSAEQSEGH----WKVKNCEERLFYICKKAGHVLSDAESGCQEGW 519 >gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo sapiens] Length = 1463 Score = 43.1 bits (100), Expect = 7e-04 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 115 CPTGWHHYEGTASCYRVY-----LSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEW 169 C W G ASC++V+ L + +A C+ LA+F+ +E FV Sbjct: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVN---- 719 Query: 170 DQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWE 204 + F W ++R+ W+G+ RN G WE Sbjct: 720 ELLHSKFNWTEERQFWIGF----NKRNPLNAGSWE 750 Score = 36.6 bits (83), Expect = 0.061 Identities = 32/170 (18%), Positives = 72/170 (42%), Gaps = 29/170 (17%) Query: 115 CPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPER 174 C GW+ Y +CY++ + + +A ++CQ N +L ++ E+ F++ Sbjct: 378 CEPGWNPYN--RNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVT-------- 427 Query: 175 SFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCA 234 G ++ + W+G + V+F+ S++ IF + + ++F Sbjct: 428 LLGDENASETWIGLS----------SNKIPVSFEWSND----SSVIFTNWHTLEPHIFPN 473 Query: 235 QLQ-CFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGF 283 + Q C H W ++C E+ ++CK++ + ++ EG+ Sbjct: 474 RSQLCVSAEQSEGH----WKVKNCEERLFYICKKAGHVLSDAESGCQEGW 519 >gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] Length = 1321 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 30/153 (19%) Query: 115 CPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPER 174 C GWH ++G CYR + + DA + C+R +G L + + +E F+ Sbjct: 1088 CDRGWHKFQG--HCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFI---------N 1136 Query: 175 SFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCA 234 SFG W+G I R+ + F+ E ++ DN F Sbjct: 1137 SFG---HENTWIGLNDRIVERDFQWTDNTGLQFENWRE-------------NQPDNFFAG 1180 Query: 235 QLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKR 267 C + H+ W+ C ++CK+ Sbjct: 1181 GEDCV---VMVAHESGRWNDVPCNYNLPYVCKK 1210 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.453 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,733,947 Number of Sequences: 37866 Number of extensions: 1608048 Number of successful extensions: 6146 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 211 Number of HSP's that attempted gapping in prelim test: 5541 Number of HSP's gapped (non-prelim): 777 length of query: 550 length of database: 18,247,518 effective HSP length: 107 effective length of query: 443 effective length of database: 14,195,856 effective search space: 6288764208 effective search space used: 6288764208 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.